Rodion: Новая страница: «The 21st Century Medicine logo '''21st Century Medicine''' ('''21CM''') is an American for-profit cryobiological research company. It has as its primary focus the development of perfusates and protocols for viable long-term cryopreservation of mammalian and human organs, tissues, and cells through the use of vitrification. With its offices and laboratories in Fontana, California, 21CM w...»

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Новая страница: «thumb|right|The 21st Century Medicine logo '''21st Century Medicine''' ('''21CM''') is an American for-profit cryobiological research company. It has as its primary focus the development of perfusates and protocols for viable long-term cryopreservation of mammalian and human organs, tissues, and cells through the use of vitrification. With its offices and laboratories in Fontana, California, 21CM w...»

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[[File:21CM logo.jpg|thumb|right|The 21st Century Medicine logo]]
'''21st Century Medicine''' ('''21CM''') is an American for-profit [[Cryobiology|cryobiological]] research company. It has as its primary focus the development of [[Perfusion|perfusates]] and protocols for viable long-term [[cryopreservation]] of mammalian and human organs, tissues, and cells through the use of [[vitrification]]. With its offices and laboratories in Fontana, California, 21CM was founded in 1993.<ref>[https://www.21cm.com/our_company.html Our Company]. 21cm.com</ref><ref>[https://www.crunchbase.com/organization/21st-century-medicine 21st Century Medicine]. crunchbase.com</ref>

21CM developed [[cryoprotectant]]s [[B1C]], [[B2C]], and [[M22]] that the [[Alcor Life Extension Foundation]] has used in vitrification of [[cryonics]] patients.<ref name="Human p. 554">[https://www.alcor.org/docs/cryopreservation-procedures-book.pdf Human Cryopreservation Procedures] (page 554)</ref> People employed at 21CM include or included [[Greg Fahy]], [[Aurelia Song]], and [[Brian Wowk]].

== History ==
In 2004, 21CM received a $900,000 grant from the U.S. National Institutes of Health (NIH) to study a preservation solution developed by the University of Rochester in New York for extending simple cold storage time of human hearts removed for [[Organ transplantation|transplant]].<ref>[https://web.archive.org/web/20160305034109/https://www.thefreelibrary.com/21st+Century+Medicine+Receives+NIH+Grant+to+Pursue+Heart+Preservation.-a0122727566 21st Century Medicine Receives NIH Grant to Pursue Heart Preservation.]. ''Business Wire''. September 30, 2004</ref>

At the July 2005 annual conference of the [[Society for Cryobiology]], 21CM announced the [[Cryopreservation of rabbit kidneys|vitrification of a rabbit kidney]] to −135 °C with their vitrification mixture. The kidney was successfully transplanted upon rewarming to a rabbit, the rabbit being euthanized on the 48th day for histological follow-up.<ref>[https://web.archive.org/web/20060830143259/http://www.me.umn.edu/events/cryo2005/program.html Plenary Session: Fundamentals of Biopreservation]. July 24, 2005</ref><ref>[[Greg Fahy|Fahy GM]], [[Brian Wowk|Wowk B]], Pagotan R, Chang A, Phan J, Thomson B, Phan L (2009). "[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781097 Physical and biological aspects of renal vitrification]". ''Organogenesis''. '''5''' (3): 167–175. doi:[https://doi.org/10.4161%2Forg.5.3.9974 10.4161/org.5.3.9974]. PMC [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781097 2781097]. PMID [https://pubmed.ncbi.nlm.nih.gov/20046680 20046680]. "After ensuring that the animal appeared capable of living indefinitely using the vitrified kidney as the sole renal support, it was euthanized for histological follow-up on day 48."</ref>

On February 9, 2016, 21CM won the [[Brain Preservation Foundation]]'s Small Mammal Brain Preservation Prize.<ref>[https://www.brainpreservation.org/small-mammal-announcement/ SMALL MAMMAL BPF PRIZE WINNING ANNOUNCEMENT]. brainpreservation.org</ref><ref>[https://www.newscientist.com/article/2077140-mammal-brain-frozen-and-thawed-out-perfectly-for-first-time/ Mammal brain frozen and thawed out perfectly for first time]. Helen Thomson. ''New Scientist''. February 11, 2016</ref> On March 13, 2018, 21CM won the Large Mammal Brain Preservation Prize.<ref>[https://www.brainpreservation.org/large-mammal-announcement/ LARGE MAMMAL BPF PRIZE WINNING ANNOUNCEMENT]. brainpreservation.org</ref><ref>[https://web.archive.org/web/20180316034524/https://gizmodo.com/new-brain-preservation-technique-could-be-a-path-to-min-1823741147 New Brain Preservation Technique Could Be a Path to Mind Uploading]. George Dvorsky. ''Gizmodo''. March 14, 2018</ref> [[Aldehyde-stabilized cryopreservation]] was used in both cases.

== Sources ==
<references/>

== External links ==
* [https://www.21cm.com/ Official website]
* Wikipedia: [https://en.wikipedia.org/wiki/21st_Century_Medicine 21st Century Medicine]
* [https://www.alcor.org/docs/cryonics-magazine-2015-04.pdf 21st Century Medicine]. ''[[Cryonics (magazine)|Cryonics]]'' 2015 #4 (pages 13–15)

[[Category:Cryonics]]
[[Category:Organizations]]
[[Category:Research]]

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