Редактирование: VTN

Vitronectin precursor (VN) (S-protein) (Serum-spreading factor) (V75) [Contains: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin-B]

==Publications==

{{medline-entry
|title=Sleep-related increase in activity of mesopontine neurons in old rats.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/12009510
|abstract=Relationships between age-related changes in sleep patterns and neuronal activity have received scant attention. In the present study, reticularis pontis oralis (RPO) and ventral tegmental nucleus of Gudden ([[VTN]]) neurons were recorded in unanesthetized restrained young (3 months) and old (23 months) Sprague-Dawley rats during wakefulness (W), slow wave sleep (SWS) and rapid eye movement (REM) sleep. All RPO neurons displayed a tonic activity. Firing rates were similar during W in young and old rats. In contrast, firing rates were higher during SWS in old rats (P < 0.001). In both young and old rats, firing rates increased significantly during REM sleep as compared to W and SWS but this increase was markedly greater in old rats. Neurons recorded from [[VTN]] displayed bursting activity at theta frequencies during W and REM sleep. The frequency of [[VTN]] bursting neurons was higher during REM sleep as compared to W in both groups of age. This difference was significantly more pronounced in old as compared to young rats (P < 0.001). Sleep-related hyperactivity of pontine neurons is discussed in terms of a possible deficit in inhibitory processes in old rats.
|mesh-terms=* Aging
* Animals
* Electroencephalography
* Electromyography
* Electrophysiology
* Male
* Neurons
* Pons
* Rats
* Rats, Sprague-Dawley
* Sleep
* Sleep, REM
* Stereotaxic Techniques
* Ventral Tegmental Area

|full-text-url=https://sci-hub.do/10.1016/s0197-4580(01)00339-6
}}