Редактирование: SSTR5

Somatostatin receptor type 5 (SS-5-R) (SS5-R) (SS5R)

==Publications==

{{medline-entry
|title=The effect of global [[SSTR5]] gene ablation on the endocrine pancreas and glucose regulation in aging mice.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/16026801
|abstract=The purpose of this study was to examine the effect of global gene ablation of [[SSTR5]] on the endocrine pancreas, insulin secretion, and glucose tolerance in aging mice, as [[SSTR5]] is a primary regulator of insulin secretion in the mouse pancreas. Global [[SSTR5]]-/- mice were generated and genotypes were verified using Southern blot and RT-PCR. Glucose tolerance and in vivo insulin secretion in [[SSTR5]]-/- and WT mice were examined using intraperitoneal glucose tolerance test (IPGTT;1.2-2.0 mg/kg) at 3 and 12 months of age (n = 8 per group). Basal and glucose-stimulated insulin secretion in vitro was studied using the isolated perfused mouse pancreas model at 3 and 12 months. Pancreata were removed and levels of insulin, glucagon, somatostatin, and [[SSTR1]] were studied using immunohistochemical analysis along with H