Редактирование: RGS5

Regulator of G-protein signaling 5 (RGS5)

==Publications==

{{medline-entry
|title=Cardiac myocytes express mRNA for ten RGS proteins: changes in RGS mRNA expression in ventricular myocytes and cultured atria.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/9827562
|abstract=Regulators of G-protein signalling (RGS) are recently identified proteins that shorten the lifetime of the activated G protein. We now show that rat cardiac myocytes express mRNA for at least 10 RGS. The mRNA for RGS-r is barely detectable in rat ventricles, but increases more than 20-fold during the 60- to 90-min process of isolating ventricular myocytes, and after 90 min of culture of atrial pieces in medium with Ca2 . Both in myocytes and in atria, the rise in RGS-r is transient. The mRNA for cardiac [[RGS5]], but not RGS-r, is developmentally regulated. These studies suggest that rapid regulation of RGS levels may be a new mechanism that governs how signals are transmitted across the cardiac cell membrane.
|mesh-terms=* Aging
* Animals
* Animals, Newborn
* Cell Membrane
* Cells, Cultured
* Eye Proteins
* GTP-Binding Proteins
* GTPase-Activating Proteins
* Gene Expression Regulation
* Heart
* Heart Atria
* Heart Ventricles
* Kinetics
* Myocardium
* Organ Specificity
* Protein Biosynthesis
* Proteins
* RGS Proteins
* RNA, Messenger
* Rats
* Reverse Transcriptase Polymerase Chain Reaction
* Signal Transduction
* Transcription, Genetic

|full-text-url=https://sci-hub.do/10.1016/s0014-5793(98)01319-2
}}