Редактирование: MT4

Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV)

==Publications==

{{medline-entry
|title=Expression pattern of four membrane-type matrix metalloproteinases in the normal and diseased mouse mammary gland.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/15895410
|abstract=Both mammary gland development and mammary carcinogenesis involve extensive remodeling of the mammary gland extracellular matrix. The expression of four membrane-type matrix metalloproteinases (MT-MMPs) with matrix remodeling potential in development and tumorigenesis was evaluated by in-situ hybridization on mouse mammary gland sections. MT1-MMP and [[MT3]]-MMP were found in the mammary stroma mainly around epithelial structures in both developing and mature mammary gland. In contrast, MT2-MMP was found exclusively in the mammary epithelium. Lactating gland expressed none of the examined MT-MMPs. Mammary gland tumors expressed MT1-MMP, MT2-MMP, and [[MT3]]-MMP while [[MT4]]-MMP was not expressed in any developmental or cancerous stage analyzed here. Our results suggest that MT1-MMP, MT2-MMP, and [[MT3]]-MMP may be involved in remodeling of both the normal and diseased mammary gland either directly or indirectly by activation of other MMPs.
|mesh-terms=* Aging
* Animals
* Female
* Gene Expression Profiling
* Gene Expression Regulation, Enzymologic
* Health
* Lactation
* Mammary Glands, Animal
* Mammary Neoplasms, Animal
* Matrix Metalloproteinase 14
* Matrix Metalloproteinase 15
* Matrix Metalloproteinase 16
* Matrix Metalloproteinases, Membrane-Associated
* Metalloendopeptidases
* Mice
* Pregnancy

|full-text-url=https://sci-hub.do/10.1002/jcp.20385
}}