Редактирование: MRO

Protein maestro (Male-specific transcription in the developing reproductive organs) (Protein B29) [B29] [C18orf3]

==Publications==

{{medline-entry
|title=[Effects of different intensities exercise combined with resveratrol on [[RBP4]] in aged obese rats].
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29926594
|abstract=To investigate the effects of different intensity exercise combined with resveratrol on retinol binding protein 4([[RBP4]]) mRNA and protein expression in visceral adipose tissue and plasma [[RBP4]] concentration of aged obese rats. Eighty male SD rats aged 3 weeks were randomly divided into the control group and the experimental group. Rats of the control group(C) were fed with ordinary feed of 6% fat ([i]n[/i]=12). The experimental group consisted of 68 rats, which were fed with 36%~40% high fat feed in three stages. The rat model of elderly obesity was established successfully. Twenty-four obese rats were selected and randomly divided into 4 groups, including obese group (CO), resveratrol obese group (RO), low intensity exercise combined with resveratrol group (LRO) and moderate intensity exercise combined with resveratrol group ([[MRO]]). There were 6 rats in each group. The exercise intensities of the LRO group and [[MRO]] group were (12 m/min×15 min) and (15 m/min×15 min). Every day was exercised for 60 minutes. The rats in RO, LRO or [[MRO]] were treated with resveratrol at the dose of 52.5 mg/kg·d, while the rats in the control group were fed with the same amount of purified water, continued intervention for 8 weeks. After 8 weeks, samples of blood, adipose tissue of around the kidney, testicle, vessel and visceral were collected. Blood glucose and plasma [[RBP4]] concentration were measured. Insulin sensitivity(ISI) was calculated. The expressions of [[RBP4]] mRNA and protein were also determined. Compared with normal (C) group, the expressions of [[RBP4]] mRNA and protein and plasma concentration and plasma glucose of the model (CO) group were increased obviously ([i]P[/i]<0.05, [i]P[/i]<0.01). ISI was decreased obviously ([i]P[/i]<0.05). Compared with model (CO) group, the expressions of [[RBP4]] mRNA and protein and plasma concentration and plasma glucose of the RO and LRO and [[MRO]] groups were decreased significantly([i]P[/i]<0.05, [i]P[/i]<0.01), while ISI was increased markedly ([i]P[/i]<0.05). Compared with the RO and LRO groups, the expressions of [[RBP4]] mRNA and protein and plasma concentration and plasma glucose of the [[MRO]] group were decreased, while ISI was increased, but there was no significant difference. Different intensities exercise combined with resveratrol could reduce the [[RBP4]] mRNA and protein expression in visceral adipose tissue and plasma [[RBP4]] concentrations of aged obese rats, but less affected by exercise intensity.
|mesh-terms=* Aging
* Animals
* Insulin Resistance
* Male
* Obesity
* Physical Conditioning, Animal
* Random Allocation
* Rats
* Rats, Sprague-Dawley
* Resveratrol
* Retinol-Binding Proteins, Plasma
* Stilbenes
|keywords=* aged obesity
* exercise intensity
* resveratrol
* retinol binding protein 4
|full-text-url=https://sci-hub.do/10.12047/j.cjap.5527.2017.110
}}