Редактирование: LRPAP1

Alpha-2-macroglobulin receptor-associated protein precursor (Alpha-2-MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP) [A2MRAP]

==Publications==

{{medline-entry
|title=Allelic frequencies at the [[ACE]] and [[LRPAP1]] loci suggest age-related relationships in a northern Italian population.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/17536759
|abstract=The present work attempts to determine the distribution of [[ACE]] and [[LRPAP1]] genotypes and allele frequencies in a sample of the population of north-western Italy and to examine the age-related association of these polymorphisms. [[ACE]] D allele frequency found in this work further confirms data obtained in previous studies of Northern Italian populations. Regarding the [[LRPAP1]] gene, high frequencies of the deleted allele in European populations were also confirmed. In order to analyse the relationship between [[ACE]] and [[LRPAP1]] gene polymorphisms and age, the sample was subdivided into four age groups: 1-30 (n= 99), 31-50 (n= 165), 51-79 (n= 146) and 80-100 years old (n= 57). For the [[ACE]] gene, significant difference in D/D genotype frequency was found only between the younger and the 51-79 age groups (p<0.05), the latter showing the lower frequency value. Significant differences were found, for both the I/D and D/D [[LRPAP1]] genotypes, between the first and the second age group (p < 0.02) and between the first and the third age group (p < 0.01), with the 51-79 age group showing the higher D/D and the lower I/D genotype frequency values.
|mesh-terms=* Adolescent
* Adult
* Aged
* Aged, 80 and over
* Aging
* Alzheimer Disease
* Child
* Child, Preschool
* Coronary Artery Disease
* European Continental Ancestry Group
* Female
* Gene Frequency
* Genotype
* Humans
* Infant
* Italy
* LDL-Receptor Related Protein-Associated Protein
* Male
* Middle Aged
* Peptidyl-Dipeptidase A
* Polymorphism, Genetic

|full-text-url=https://sci-hub.do/10.1080/03014460601079845
}}
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