Редактирование: FGL2

Fibroleukin precursor (Fibrinogen-like protein 2) (pT49)

==Publications==

{{medline-entry
|title=Developmental expression of B cell molecules in equine lymphoid tissues.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28063478
|abstract=Identification and classification of B cell subpopulations has been shown to be challenging and inconsistent among different species. Our study tested aspects of ontogeny, phenotype, tissue distribution, and function of equine [[CD5]]  B cells, which represented a greater proportion of B cells early in development and in the peritoneal cavity. [[CD5]]  and [[CD5]]  B cells differentially expressed B cell markers (CD2, CD21, IgM) measured using flow cytometry, but similar mRNA expression of signature genes (DGKA, [[FGL2]], [[PAX5]], [[IGHM]], IL10) measured using quantitative RT-PCR. Sequencing lambda light chain segments revealed that [[CD5]]  B cells generated diverse immunoglobulin repertoires, and more frequently bound to fluorescence-labeled phosphorylcholine. This study shows developmental characteristics and tissue distribution of a newly described subpopulation of B cells in the horse.
|mesh-terms=* Aging
* Animals
* B-Lymphocyte Subsets
* B-Lymphocytes
* CD5 Antigens
* Flow Cytometry
* Horses
* Immunoglobulin Light Chains
* Immunophenotyping
* Lymphoid Tissue
* Phosphorylcholine
|keywords=* B cell
* CD5
* Development
* Equine
* Immunoglobulin repertoire
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267323
}}