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Aging genes 90-99
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__NOTOC__ * [[Aging genes 300|Genes with 300 and more publications]] * [[Aging genes 200-299|Genes with 200-299 publications]] * [[Aging genes 100-199|Genes with 100-199 publications]] * [[Aging genes 90-99|Genes with 90-99 publications]] * [[Aging genes 80-89|Genes with 80-89 publications]] * [[Aging genes 70-79|Genes with 70-79 publications]] * [[Aging genes 60-69|Genes with 60-69 publications]] * [[Aging genes 50-59|Genes with 50-59 publications]] * [[Aging genes 40-49|Genes with 40-49 publications]] * [[Aging genes 30-39|Genes with 30-39 publications]] * [[Aging genes 20-29|Genes with 20-29 publications]] * [[Aging genes 10-19|Genes with 10-19 publications]] * [[Aging genes 5-9|Genes with 5-9 publications]] * [[Aging genes 3-4|Genes with 3-4 publications]] * [[Aging genes 1-2|Genes with 1-2 publications]] * [[Aging_genes_A-Z_table]] ==SIRT3== * {{medline-title |title=[[SIRT3]] protects endothelial cells from high glucose-induced senescence and dysfunction via the p53 pathway. |date=05.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33160987 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118724 }} * {{medline-title |title=Melatonin and Sirtuins in Buccal Epithelium: Potential Biomarkers of Aging and Age-Related Pathologies. |date=30.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143333 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662974 }} * {{medline-title |title=Sirtuins as Possible Predictors of Aging and Alzheimer's Disease Development: Verification in the Hippocampus and Saliva. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33098511 |full-text-url=https://sci-hub.do/10.1007/s10517-020-04986-4 }} * {{medline-title |title=The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32919015 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111090 }} * {{medline-title |title=Ginsenoside Rg1 protects against Sca-1 HSC/HPC cell aging by regulating the [[SIRT1]]-[[FOXO3]] and [[SIRT3]]-[[SOD2]] signaling pathways in a γ-ray irradiation-induced aging mice model. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32765665 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388550 }} * {{medline-title |title=[i][[SIRT3]][/i] Transfection of Aged Human Bone Marrow-Derived Mesenchymal Stem Cells Improves Cell Therapy-Mediated Myocardial Repair. |date=28.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32228121 |full-text-url=https://sci-hub.do/10.1089/rej.2019.2260 }} * {{medline-title |title=17β-estradiol inhibits H O -induced senescence in HUVEC cells through upregulating [[SIRT3]] expression and promoting autophagy. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32172411 |full-text-url=https://sci-hub.do/10.1007/s10522-020-09868-w }} * {{medline-title |title=CR6 interacting factor 1 deficiency induces premature senescence via [[SIRT3]] inhibition in endothelial cells. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32109515 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2020.02.017 }} * {{medline-title |title=[Metabolic Alteration in Aging Process: Metabolic Remodeling in White Adipose Tissue by Caloric Restriction]. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32115557 |full-text-url=https://sci-hub.do/10.1248/yakushi.19-00193-2 }} * {{medline-title |title=Glucose-induced oxidative stress and accelerated aging in endothelial cells are mediated by the depletion of mitochondrial SIRTs. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32026628 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002531 }} * {{medline-title |title=Mitochondrial function in skeletal myofibers is controlled by a TRF2-[[SIRT3]] axis over lifetime. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31991048 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059141 }} * {{medline-title |title=Context-Dependent Roles for [[SIRT2]] and [[SIRT3]] in Tumor Development Upon Calorie Restriction or High Fat Diet. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31970087 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960403 }} * {{medline-title |title=The yin and yang faces of the mitochondrial deacetylase sirtuin 3 in age-related disorders. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31740222 |full-text-url=https://sci-hub.do/10.1016/j.arr.2019.100983 }} * {{medline-title |title=Inhibition of Mitochondrial Calcium Overload by [[SIRT3]] Prevents Obesity- or Age-Related Whitening of Brown Adipose Tissue. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31712319 |full-text-url=https://sci-hub.do/10.2337/db19-0526 }} * {{medline-title |title=Lysine malonylation and propionylation are prevalent in human lens proteins. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31678036 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957740 }} * {{medline-title |title=Metabolism and biochemical properties of nicotinamide adenine dinucleotide (NAD) analogs, nicotinamide guanine dinucleotide (NGD) and nicotinamide hypoxanthine dinucleotide (NHD). |date=11.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31511627 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739475 }} * {{medline-title |title=[i]Sirt3[/i] Deficiency Shortens Life Span and Impairs Cardiac Mitochondrial Function Rescued by [i]Opa1[/i] Gene Transfer. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31269804 |full-text-url=https://sci-hub.do/10.1089/ars.2018.7703 }} * {{medline-title |title=Low-Dose Pesticide Mixture Induces Accelerated Mesenchymal Stem Cell Aging In Vitro. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30977188 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850038 }} * {{medline-title |title=[[NLRP3]]/IL1β inflammasome associated with the aging bladder triggers bladder dysfunction in female rats. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30720125 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423574 }} * {{medline-title |title=Targeted Mitochondrial COQ Delivery Attenuates Antiretroviral-Drug-Induced Senescence of Neural Progenitor Cells. |date=04.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30592424 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364271 }} * {{medline-title |title=Caffeine Protects Skin from Oxidative Stress-Induced Senescence through the Activation of Autophagy. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30555576 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276298 }} * {{medline-title |title=The pathophysiological importance and therapeutic potential of NAD' biosynthesis and mitochondrial sirtuin [[SIRT3]] in age-associated diseases. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30557475 }} * {{medline-title |title=Aging-Related Overactivity of the Angiotensin/AT1 Axis Decreases Sirtuin 3 Levels in the Substantia Nigra, Which Induces Vulnerability to Oxidative Stress and Neurodegeneration. |date=14.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30412227 |full-text-url=https://sci-hub.do/10.1093/gerona/gly259 }} * {{medline-title |title=6-gingerol ameliorates age-related hepatic steatosis: Association with regulating lipogenesis, fatty acid oxidation, oxidative stress and mitochondrial dysfunction. |date=01.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30408433 |full-text-url=https://sci-hub.do/10.1016/j.taap.2018.11.001 }} * {{medline-title |title=Sirtuins and NAD in the Development and Treatment of Metabolic and Cardiovascular Diseases. |date=14.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30355082 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206880 }} * {{medline-title |title=Moderate calorie restriction attenuates age‑associated alterations and improves cardiac function by increasing [[SIRT1]] and [[SIRT3]] expression. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30132522 |full-text-url=https://sci-hub.do/10.3892/mmr.2018.9390 }} * {{medline-title |title=Melatonin Mitigates Mitochondrial Meltdown: Interactions with [[SIRT3]]. |date=18.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30126181 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121285 }} * {{medline-title |title=Master athletes have higher miR-7, [[SIRT3]] and [[SOD2]] expression in skeletal muscle than age-matched sedentary controls. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30107294 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092475 }} * {{medline-title |title=Sirtuin3 protects aged human mesenchymal stem cells against oxidative stress and enhances efficacy of cell therapy for ischaemic heart diseases. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30091830 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201360 }} * {{medline-title |title=Sirtuins in Renal Health and Disease. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29712732 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050939 }} * {{medline-title |title=Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29654651 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052469 }} * {{medline-title |title=Physical Exercise Improves Aging-Related Changes in Angiotensin, IGF-1, [[SIRT1]], [[SIRT3]], and VEGF in the Substantia Nigra. |date=10.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659739 |full-text-url=https://sci-hub.do/10.1093/gerona/gly072 }} * {{medline-title |title=Differential gene expression of sirtuins between somatotropinomas and nonfunctioning pituitary adenomas. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29564694 |full-text-url=https://sci-hub.do/10.1007/s11102-018-0881-7 }} * {{medline-title |title=NAD supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency. |date=20.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29432159 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828618 }} * {{medline-title |title=Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29366775 |full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.01.018 }} * {{medline-title |title=Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of [[SIRT3]]. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29289557 |full-text-url=https://sci-hub.do/10.1016/j.mad.2017.12.005 }} * {{medline-title |title=Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063982 |full-text-url=https://sci-hub.do/10.1007/s10571-017-0557-2 }} * {{medline-title |title=[Protective effect of total saponins of Panax notoginseng combined with total flavonoids of epimedium on D-galactose-incuced senescence of H9c2 cell]. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28952264 |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.2017.0012 }} * {{medline-title |title=Obesity and aging diminish sirtuin 1 ([[SIRT1]])-mediated deacetylation of [[SIRT3]], leading to hyperacetylation and decreased activity and stability of [[SIRT3]]. |date=20.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28808064 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655509 }} * {{medline-title |title=miR-34a and miR-9 are overexpressed and SIRT genes are downregulated in peripheral blood mononuclear cells of aging humans. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28699360 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544174 }} * {{medline-title |title=EphB2 signaling-mediated Sirt3 expression reduces [[MSC]] senescence by maintaining mitochondrial ROS homeostasis. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28687409 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2017.07.001 }} * {{medline-title |title=Upregulation of mitochondrial NAD levels impairs the clonogenicity of SSEA1 glioblastoma tumor-initiating cells. |date=09.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28604662 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519015 }} * {{medline-title |title=Identification of tissue-specific transcriptional markers of caloric restriction in the mouse and their use to evaluate caloric restriction mimetics. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28556428 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506434 }} * {{medline-title |title=Longevity and healthy ageing genes FOXO3A and [[SIRT3]]: Serum protein marker and new road map to burst oxidative stress by Withania somnifera. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28526626 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.05.013 }} * {{medline-title |title=Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts. |date=01.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28385812 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495944 }} * {{medline-title |title=Mitochondrial Sirtuins and Molecular Mechanisms of Aging. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28285806 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713479 }} * {{medline-title |title=Melatonin and sirtuins: A "not-so unexpected" relationship. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28109165 |full-text-url=https://sci-hub.do/10.1111/jpi.12391 }} * {{medline-title |title=[[SIRT3]] mediates decrease of oxidative damage and prevention of ageing in porcine fetal fibroblasts. |date=15.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28131761 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2017.01.010 }} * {{medline-title |title=The Role of Mitochondrial Non-Enzymatic Protein Acylation in Ageing. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28033361 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199114 }} * {{medline-title |title=Melatonin improves age-induced fertility decline and attenuates ovarian mitochondrial oxidative stress in mice. |date=12.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27731402 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059725 }} * {{medline-title |title=Gardenia jasminoides extract-capped gold nanoparticles reverse hydrogen peroxide-induced premature senescence. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27693841 |full-text-url=https://sci-hub.do/10.1016/j.jphotobiol.2016.09.033 }} * {{medline-title |title=Function of the [[SIRT3]] mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative disease. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27686535 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242307 }} * {{medline-title |title=Sirtuin 3 Deregulation Promotes Pulmonary Fibrosis. |date=01.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27522058 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964739 }} * {{medline-title |title=Effects of Grape Skin Extract on Age-Related Mitochondrial Dysfunction, Memory and Life Span in C57BL/6J Mice. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27455862 |full-text-url=https://sci-hub.do/10.1007/s12017-016-8428-4 }} * {{medline-title |title=Restoration of Mitochondrial NAD Levels Delays Stem Cell Senescence and Facilitates Reprogramming of Aged Somatic Cells. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27428041 |full-text-url=https://sci-hub.do/10.1002/stem.2460 }} * {{medline-title |title=Mitochondrial Sirtuin 3 and Renal Diseases. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27362524 |full-text-url=https://sci-hub.do/10.1159/000444370 }} * {{medline-title |title=[[CD38]] Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an [[SIRT3]]-Dependent Mechanism. |date=14.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27304511 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911708 }} * {{medline-title |title=The role of mitochondrial sirtuins in health and disease. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27164052 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2016.04.197 }} * {{medline-title |title=Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins. |date=15.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27038700 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.03.015 }} * {{medline-title |title=Manganese Superoxide Dismutase Acetylation and Dysregulation, Due to Loss of [[SIRT3]] Activity, Promote a Luminal B-Like Breast Carcinogenic-Permissive Phenotype. |date=20.08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26935174 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991597 }} * {{medline-title |title=Sirtuins, Cell Senescence, and Vascular Aging. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26948035 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848124 }} * {{medline-title |title=[[SIRT3]] Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3β. |date=14.12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26667039 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760222 }} * {{medline-title |title=The expression levels of the sirtuins in patients with BCC. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26631040 |full-text-url=https://sci-hub.do/10.1007/s13277-015-4522-8 }} * {{medline-title |title=Effects of Aging and Cardiovascular Disease Risk Factors on the Expression of Sirtuins in the Human Corpus Cavernosum. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26556180 |full-text-url=https://sci-hub.do/10.1111/jsm.13035 }} * {{medline-title |title=Localization of sirtuins ([[SIRT1]]-7) in the aged mouse inner ear. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26472659 |full-text-url=https://sci-hub.do/10.3109/00016489.2015.1093172 }} * {{medline-title |title=Are sirtuins markers of ovarian aging? |date=10.01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26403315 |full-text-url=https://sci-hub.do/10.1016/j.gene.2015.09.043 }} * {{medline-title |title=The Role of Mitochondrial DNA in Mediating Alveolar Epithelial Cell Apoptosis and Pulmonary Fibrosis. |date=07.09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26370974 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613264 }} * {{medline-title |title=Sirtuin-dependent clock control: new advances in metabolism, aging and cancer. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26335311 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610809 }} * {{medline-title |title=Mitochondrial Aging and Physical Decline: Insights From Three Generations of Women. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26297939 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675931 }} * {{medline-title |title=Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating Sirtuin. |date=08.07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26153625 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648391 }} * {{medline-title |title=[[SIRT3]] regulates progression and development of diseases of aging. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26138757 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558250 }} * {{medline-title |title=Sirtuin Functions in Female Fertility: Possible Role in Oxidative Stress and Aging. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26075037 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436464 }} * {{medline-title |title=Differential expression of sirtuins in the aging rat brain. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26005404 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424846 }} * {{medline-title |title=A conserved transcriptional signature of delayed aging and reduced disease vulnerability is partially mediated by [[SIRT3]]. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25830335 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382298 }} * {{medline-title |title=Expression of [[SIRT1]] and [[SIRT3]] varies according to age in mice. |date=03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25806122 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371181 }} * {{medline-title |title=Practicality of intermittent fasting in humans and its effect on oxidative stress and genes related to aging and metabolism. |date=04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25546413 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403246 }} * {{medline-title |title=Differential Effect of Endurance Training on Mitochondrial Protein Damage, Degradation, and Acetylation in the Context of Aging. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25504576 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612384 }} * {{medline-title |title=Decreased [[SIRT3]] in aged human mesenchymal stromal/stem cells increases cellular susceptibility to oxidative stress. |date=11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25210848 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224562 }} * {{medline-title |title=Sirtuins: guardians of mammalian healthspan. |date=07.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24877878 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077918 }} * {{medline-title |title=[[SIRT3]] deficiency exacerbates ischemia-reperfusion injury: implication for aged hearts. |date=15.06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24748594 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059981 }} * {{medline-title |title=Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and aging. |date=17.01.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24436432 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228987 }} * {{medline-title |title=Partial reversal of skeletal muscle aging by restoration of normal NAD⁺ levels. |date=02.2014 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A critical review on its relevance to the longevity effect induced by calorie restriction. |date=06.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23661364 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887872 }} * {{medline-title |title=[[SIRT3]] overexpression antagonizes high glucose accelerated cellular senescence in human diploid fibroblasts via the [[SIRT3]]-[[FOXO1]] signaling pathway. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23494737 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825003 }} ==SOD2== * {{medline-title |title=Astaxanthin Counteracts Vascular Calcification In Vitro Through an Early Up-Regulation of [[SOD2]] Based on a Transcriptomic Approach. |date=12.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33198315 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698184 }} * {{medline-title |title=Alginate Oligosaccharide Prevents against D-galactose-mediated Cataract in C57BL/6J Mice via Regulating Oxidative 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p53 and mTOR/AKT promote an in vivo switch from apoptosis to senescence upon telomere shortening in zebrafish. |date=19.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32427102 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237213 }} * {{medline-title |title=Aging alters acetylation status in skeletal and cardiac muscles. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32300965 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286993 }} * {{medline-title |title=Doxorubicin-induced normal breast epithelial cellular aging and its related breast cancer growth through mitochondrial autophagy and oxidative stress mitigated by ginsenoside Rh2. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32100342 |full-text-url=https://sci-hub.do/10.1002/ptr.6636 }} * {{medline-title |title=Bioactive peptides derived from crimson snapper and in vivo anti-aging effects on fat diet-induced high fat Drosophila melanogaster. |date=29.01.2020 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of Rat Heart. |date=30.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31647296 |full-text-url=https://sci-hub.do/10.33549/physiolres.934170 }} * {{medline-title |title=Impact of curcumin on replicative and chronological aging in the Saccharomyces cerevisiae yeast. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31659616 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942599 }} * {{medline-title |title=[[CD38]] Deficiency Alleviates D-Galactose-Induced Myocardial Cell Senescence Through NAD /Sirt1 Signaling Pathway. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31551807 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735286 }} * {{medline-title |title=MicroRNA-34a (miR-34a) Mediates Retinal Endothelial Cell Premature Senescence through Mitochondrial Dysfunction and Loss of Antioxidant Activities. |date=22.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31443378 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769710 }} * {{medline-title |title=Age-Dependent Oxidative Stress Elevates Arginase 1 and Uncoupled Nitric Oxide Synthesis in Skeletal Muscle of Aged Mice. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31205583 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530149 }} * {{medline-title |title=Age-Related Oxidative Changes in Primary Porcine Fibroblasts Expressing Mutated Huntingtin. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31167196 |full-text-url=https://sci-hub.do/10.1159/000500091 }} * {{medline-title |title=Preventive effect of Lactobacillus plantarum KSFY02 isolated from naturally fermented yogurt from Xinjiang, China, on d-galactose-induced oxidative aging in mice. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31103296 |full-text-url=https://sci-hub.do/10.3168/jds.2018-16033 }} * {{medline-title |title=Protective effects of pyrroloquinoline quinine against oxidative stress-induced cellular senescence and inflammation in human renal tubular 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age-related changes in the experimental Trypanosoma cruzi infection: Age-related thymic dysfunctions and Trypanosoma cruzi infection. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30130728 |full-text-url=https://sci-hub.do/10.1016/j.cyto.2018.08.004 }} * {{medline-title |title=Mitohormesis in Mice via Sustained Basal Activation of Mitochondrial and Antioxidant Signaling. |date=06.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30122556 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221994 }} * {{medline-title |title=Master athletes have higher miR-7, [[SIRT3]] and [[SOD2]] expression in skeletal muscle than age-matched sedentary controls. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30107294 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092475 }} * {{medline-title |title=Age-related changes in vascular responses to angiotensin-(1-7) in female mice. |date=07-09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30024321 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053867 }} * {{medline-title |title=Effect of β-D-Mannuronic Acid (M2000) on Oxidative Stress Enzymes' Gene Using Healthy Donor Peripheral Blood Mononuclear Cells for Evaluating the Anti-Aging Property. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29766814 |full-text-url=https://sci-hub.do/10.2174/1570163815666180515122834 }} * {{medline-title |title=The impact of preserved Klotho gene expression on antioxidative stress activity in healthy kidney. |date=01.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29693450 |full-text-url=https://sci-hub.do/10.1152/ajprenal.00486.2017 }} * {{medline-title |title=Age-related NMDA signaling alterations in [[SOD2]] deficient mice. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577983 |full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.03.019 }} * {{medline-title |title=Inhibition of oxidative stress in cholinergic projection neurons fully rescues 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|title=Time-response characteristic and potential biomarker identification of heavy metal induced toxicity in zebrafish. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29111395 |full-text-url=https://sci-hub.do/10.1016/j.fsi.2017.10.047 }} * {{medline-title |title=Dietary supplementation with acetyl-l-carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807823 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.017 }} * {{medline-title |title=Aerobic exercise prevents rarefaction of pial collaterals and increased stroke severity that occur with aging. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28685617 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669350 }} * {{medline-title |title=Betaine promotes cell differentiation of human osteoblasts in primary culture. |date=07.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28592272 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463390 }} * {{medline-title |title=Vulnerability of white matter tracts and cognition to the [[SOD2]] polymorphism: A preliminary study of antioxidant defense genes in brain aging. |date=30.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28457881 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515475 }} * {{medline-title |title=Age-related reduction in the expression of FOXO transcription factors and correlations with intervertebral disc degeneration. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28430387 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650945 }} * {{medline-title |title=Ionizing radiation induces long-term senescence in endothelial cells through mitochondrial respiratory complex II dysfunction and superoxide generation. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28431961 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2017.04.019 }} * {{medline-title |title=An in vitro evaluation of anti-aging effect of guluronic acid (G2013) based on enzymatic oxidative stress gene expression using healthy individuals PBMCs. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28364598 |full-text-url=https://sci-hub.do/10.1016/j.biopha.2017.03.066 }} * {{medline-title |title=The In Vitro Influence of a Genetic Superoxide-Hydrogen Peroxide Imbalance on Immunosenescence. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28285577 |full-text-url=https://sci-hub.do/10.1089/rej.2016.1892 }} * {{medline-title |title=Anti-aging effects of M2000 (β-D-mannuronic acid) as a novel immunosuppressive drug on the enzymatic and non-enzymatic oxidative stress parameters in an experimental model. |date=01.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28207414 |full-text-url=https://sci-hub.do/10.1515/jbcpp-2016-0092 }} * {{medline-title |title=Expression of cellular protective proteins [[SIRT1]], HSP70 and [[SOD2]] correlates with age and is significantly higher in NK cells of the oldest seniors. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28127381 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259875 }} * {{medline-title |title=[[SIRT3]] mediates decrease of oxidative damage and prevention of ageing in porcine fetal fibroblasts. |date=15.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28131761 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2017.01.010 }} * {{medline-title |title=Loss of BOSS Causes Shortened Lifespan with Mitochondrial Dysfunction in Drosophila. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28045997 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207625 }} * {{medline-title |title=Altered S-nitrosylation of p53 is responsible for impaired antioxidant response in skeletal muscle during aging. |date=20.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28025407 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{{medline-title |title=Exercise-Mediated Increase in Nigral Tyrosine Hydroxylase Is Accompanied by Increased Nigral GFR-α1 and EAAC1 Expression in Aging Rats. |date=17.02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26599339 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926611 }} * {{medline-title |title=Differences in Mouse Hepatic Thyroid Hormone Transporter Expression with Age and Hyperthyroidism. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26601077 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640301 }} * {{medline-title |title=Influence of caffeine on 3,4-methylenedioxymethamphetamine-induced dopaminergic neuron degeneration and neuroinflammation is age-dependent. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26442661 |full-text-url=https://sci-hub.do/10.1111/jnc.13377 }} * {{medline-title |title=Reduction in [[NPY]]-positive neurons and dysregulation of excitability in young senescence-accelerated mouse prone 8 (SAMP8) hippocampus precede the onset of cognitive impairment. |date=10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26250996 |full-text-url=https://sci-hub.do/10.1111/jnc.13274 }} * {{medline-title |title=Familial Longevity Is Associated With Higher TSH Secretion and Strong TSH-fT3 Relationship. |date=10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26230295 |full-text-url=https://sci-hub.do/10.1210/jc.2015-2624 }} * {{medline-title |title=Human longevity is characterised by high thyroid stimulating hormone secretion without altered energy metabolism. |date=19.06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26089239 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473605 }} * {{medline-title |title=Circulating sclerostin and dickkopf-1 levels in ossification of the posterior longitudinal ligament of the spine. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26040409 |full-text-url=https://sci-hub.do/10.1007/s00774-015-0671-5 }} * {{medline-title |title=Improving effect of chronic resveratrol treatment on central monoamine synthesis and cognition in aged rats. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25895558 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404420 }} * {{medline-title |title=The gender-differentiated antioxidant effects of a lutein-containing supplement in the aqueous humor of patients with senile cataracts. |date=12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25305576 |full-text-url=https://sci-hub.do/10.1016/j.exer.2014.10.009 }} * {{medline-title |title=Oxidative stress associated with middle aging leads to sympathetic hyperactivity and downregulation of soluble guanylyl cyclase in corpus cavernosum. |date=15.11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25217652 |full-text-url=https://sci-hub.do/10.1152/ajpheart.00708.2013 }} * {{medline-title |title=Bone turnover markers predict hip bone loss in elderly European men: results of the European Male Ageing Study (EMAS). 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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32785991 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534619 }} * {{medline-title |title=[[ATM]]-deficient neural precursors develop senescence phenotype with disturbances in autophagy. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32621937 |full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111296 }} * {{medline-title |title=[[ATM]] is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging. |date=22.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32201398 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138542 }} * {{medline-title |title=[[ATM]] suppresses leaf senescence triggered by DNA double-strand break through epigenetic control of senescence-associated genes in Arabidopsis. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32163596 |full-text-url=https://sci-hub.do/10.1111/nph.16535 }} * {{medline-title |title=Glioblastoma Cells Do Not Affect Axitinib-Dependent Senescence of HUVECs in a Transwell Coculture Model. |date=21.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32098270 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073100 }} * {{medline-title |title=Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. |date=05.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32109421 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058826 }} * {{medline-title |title=Declining BRCA-Mediated DNA Repair in Sperm Aging and its Prevention by Sphingosine-1-Phosphate. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31916095 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065969 }} * {{medline-title |title=BRCA-related [[ATM]]-mediated DNA double-strand break repair and ovarian aging. |date=01.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31822904 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935693 }} * {{medline-title |title=[[ATM]] Deficiency Accelerates DNA Damage, Telomere Erosion, and Premature T Cell Aging in HIV-Infected Individuals on Antiretroviral Therapy. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31781094 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856652 }} * {{medline-title |title=NF-κB signaling in skin aging. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31634486 |full-text-url=https://sci-hub.do/10.1016/j.mad.2019.111160 }} * {{medline-title |title=[[SMG1]] heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31565865 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850945 }} * {{medline-title |title=LncRNA RP11-670E13.6, interacted with hnRNPH, delays cellular senescence by sponging microRNA-663a in UVB damaged dermal fibroblasts. |date=23.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31444317 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738423 }} * {{medline-title |title=Phosphoproteomic analysis reveals plant DNA damage signalling pathways with a functional role for histone [[H2AX]] phosphorylation in plant growth under genotoxic stress. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31410901 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900162 }} * {{medline-title |title=Tel1/[[ATM]] Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31391264 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781906 }} * {{medline-title |title=Curcumin induces multiple signaling pathways leading to vascular smooth muscle cell senescence. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31372798 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790191 }} * {{medline-title |title=Long-term culture of mesenchymal stem cells impairs [[ATM]]-dependent recognition of DNA breaks and increases genetic instability. |date=29.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31358047 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664790 }} * {{medline-title |title=Genetic background, epigenetic factors and dietary interventions which influence human longevity. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31309340 |full-text-url=https://sci-hub.do/10.1007/s10522-019-09824-3 }} * {{medline-title |title=Repair-independent functions of DNA-PKcs protect irradiated cells from mitotic slippage and accelerated senescence. |date=01.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31189537 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633392 }} * {{medline-title |title=Meeting report of the 14th Japan-Korea joint symposium on cancer and aging research: current status of translational research and approaches to precision medicine. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30859317 |full-text-url=https://sci-hub.do/10.1007/s00432-019-02887-2 }} * {{medline-title |title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287 }} * {{medline-title |title=Alleviation of Senescence via [[ATM]] Inhibition in Accelerated Aging Models. |date=31.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30726661 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449716 }} * {{medline-title |title=Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence. |date=01.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30735837 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2019.02.005 }} * {{medline-title |title=Genomic insult oriented mitochondrial instability and proliferative hindrance in the bone marrow of aplastic mice including stem/progenitor population. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30683472 |full-text-url=https://sci-hub.do/10.1016/j.prp.2019.01.028 }} * {{medline-title |title=N-Myc promotes therapeutic resistance development of neuroendocrine prostate cancer by differentially regulating miR-421/[[ATM]] pathway. |date=18.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30657058 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337850 }} * {{medline-title |title=Hydrogen Indirectly Suppresses Increases in Hydrogen Peroxide in Cytoplasmic Hydroxyl Radical-Induced Cells and Suppresses Cellular Senescence. |date=21.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30669692 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359316 }} * {{medline-title |title=Low dose dinaciclib enhances doxorubicin-induced senescence in myeloma RPMI8226 cells by transformation of the p21 and p16 pathways. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30405800 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202540 }} * {{medline-title |title=The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30235328 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147527 }} * {{medline-title |title=Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells. |date=05.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30194939 |full-text-url=https://sci-hub.do/10.1016/j.ejphar.2018.09.005 }} * {{medline-title |title=The SCF ubiquitin ligase complex mediates degradation of the tumor suppressor [[FBXO31]] and thereby prevents premature cellular senescence. |date=19.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171069 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200945 }} * {{medline-title |title=Defenses against Pro-oxidant Forces - Maintenance of Cellular and Genomic Integrity and Longevity. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040046 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203329 }} * {{medline-title |title=The ING1a model of rapid cell senescence. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29928906 |full-text-url=https://sci-hub.do/10.1016/j.mad.2018.06.004 }} * {{medline-title |title=Human electronegative LDL induces mitochondrial dysfunction and premature senescence of vascular cells in vivo. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29923368 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052487 }} * {{medline-title |title=Boosting [[ATM]] activity alleviates aging and extends lifespan in a mouse model of progeria. |date=02.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29717979 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957528 }} * {{medline-title |title=Inflammation, a significant player of Ataxia-Telangiectasia pathogenesis? |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29582093 |full-text-url=https://sci-hub.do/10.1007/s00011-018-1142-y }} * {{medline-title |title=Transcriptional Repression of High-Mobility Group Box 2 by p21 in Radiation-Induced Senescence. |date=30.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487276 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935093 }} * {{medline-title |title=Senescence-messaging secretome factors trigger premature senescence in human endometrium-derived stem cells. |date=19.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397942 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.01.163 }} * {{medline-title |title=Bisphenol A induces DSB-[[ATM]]-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29275510 |full-text-url=https://sci-hub.do/10.1007/s00204-017-2150-3 }} * {{medline-title |title=Global mapping of transcription factor motifs in human aging. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29293662 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749797 }} * {{medline-title |title=Ataxia-Telangiectasia Mutated Modulation of Carbon Metabolism in Cancer. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29238697 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712564 }} * {{medline-title |title=DNA damage, metabolism and aging in pro-inflammatory T cells: Rheumatoid arthritis as a model system. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29101015 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871568 }} * {{medline-title |title=Genetic interrogation of replicative senescence uncovers a dual role for [[USP28]] in coordinating the p53 and [[GATA4]] branches of the senescence program. |date=01.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29089421 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710139 }} * {{medline-title |title=A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress. |date=10.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28797244 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553741 }} * {{medline-title |title=Haplodeficiency of Ataxia Telangiectasia Mutated Accelerates Heart Failure After Myocardial Infarction. |date=19.07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28724653 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586323 }} * {{medline-title |title=iTRAQ-based proteomic profiling of granulosa cells from lamb and ewe after superstimulation. |date=01.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28708522 |full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2017.06.014 }} * {{medline-title |title=[The Role of DNA Double-strain Damage Repairing Mechanisms in Diabetic Atheroscolersis]. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28612525 }} * {{medline-title |title=The DNA Damage Response in Neurons: Die by Apoptosis or Survive in a Senescence-Like State? |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28436392 |full-text-url=https://sci-hub.do/10.3233/JAD-161221 }} * {{medline-title |title=Chemical screening identifies [[ATM]] as a target for alleviating senescence. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28346404 |full-text-url=https://sci-hub.do/10.1038/nchembio.2342 }} * {{medline-title |title=Age and Adaptation: Stronger Decision Updating about Real World Risks in Older Age. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28095602 |full-text-url=https://sci-hub.do/10.1111/risa.12710 }} * {{medline-title |title=Accumulation of spontaneous γH2AX foci in long-term cultured mesenchymal stromal cells. |date=11.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27959319 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270682 }} * {{medline-title |title=Calcium alterations signal either to senescence or to autophagy induction in stem cells upon oxidative stress. |date=08.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27941214 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270676 }} * {{medline-title |title=Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27895165 |full-text-url=https://sci-hub.do/10.1189/jlb.4VMA0716-316R }} * {{medline-title |title=[[ATM]]-ROS-iNOS axis regulates nitric oxide mediated cellular senescence. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27845209 |full-text-url=https://sci-hub.do/10.1016/j.bbamcr.2016.11.008 }} * {{medline-title |title=NAD Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair. |date=11.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27732836 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777858 }} * {{medline-title |title=Overcoming [[ATM]] Deficiency by Activating the NAD /[[SIRT1]] Axis. |date=11.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27732834 |full-text-url=https://sci-hub.do/10.1016/j.cmet.2016.09.019 }} * {{medline-title |title=Perturbed hematopoiesis in mice lacking [[ATM]]IN. |date=20.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27581360 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147016 }} * {{medline-title |title=BRCA-1 Gene Expression and Comparative Proteomic Profile of Primordial Follicles from Young and Adult Buffalo (Bubalus bubalis) Ovaries. |date=03.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27552356 |full-text-url=https://sci-hub.do/10.1080/10495398.2016.1210613 }} * {{medline-title |title=[[IFI16]], an amplifier of DNA-damage response: Role in cellular senescence and aging-associated inflammatory diseases. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27063514 |full-text-url=https://sci-hub.do/10.1016/j.arr.2016.04.002 }} * {{medline-title |title=Transcription factor Sp1 prevents TRF2(ΔBΔM)-induced premature senescence in human diploid fibroblasts. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26906205 |full-text-url=https://sci-hub.do/10.1007/s11010-016-2672-7 }} * {{medline-title |title=Mitochondria are required for pro-ageing features of the senescent phenotype. |date=01.04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26848154 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818766 }} * {{medline-title |title=Induction of DNA double-strand breaks and cellular senescence by human respiratory syncytial virus. |date=18.05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26809688 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871660 }} * {{medline-title |title=A gain-of-function senescence bypass screen identifies the homeobox transcription factor [[DLX2]] as a regulator of [[ATM]]-p53 signaling. |date=01.02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26833729 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743059 }} * {{medline-title |title=Tetraploidization or autophagy: The ultimate fate of senescent human endometrial stem cells under [[ATM]] or p53 inhibition. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26636375 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825783 }} * {{medline-title |title=Health risks for ataxia-telangiectasia mutated heterozygotes: a systematic review, meta-analysis and evidence-based guideline. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26662178 |full-text-url=https://sci-hub.do/10.1111/cge.12710 }} * {{medline-title |title=The DNA damage response induces inflammation and senescence by inhibiting autophagy of [[GATA4]]. |date=25.09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26404840 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942138 }} * {{medline-title |title=BRCA Mutations, DNA Repair Deficiency, and Ovarian Aging. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26224004 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710189 }} * {{medline-title |title=[Advances of Research on Ataxia Telangiectasia Mutated Gene and Risk Factors of Cardiovascular Disease]. |date=04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26211275 }} * {{medline-title |title=Requirement of [[ATR]] for maintenance of intestinal stem cells in aging Drosophila. |date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26000719 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468312 }} * {{medline-title |title=Temporally distinct roles of [[ATM]] and ROS in genotoxic-stress-dependent induction and maintenance of cellular senescence. |date=15.01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25416819 |full-text-url=https://sci-hub.do/10.1242/jcs.159517 }} * {{medline-title |title=Selenoprotein H suppresses cellular senescence through genome maintenance and redox regulation. |date=05.12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25336634 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256366 }} * {{medline-title |title=A switch-like dynamic mechanism for the initiation of replicative senescence. |date=28.11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25315415 |full-text-url=https://sci-hub.do/10.1016/j.febslet.2014.09.043 }} * {{medline-title |title=Autophagy inhibition switches low-dose camptothecin-induced premature senescence to apoptosis in human colorectal cancer cells. |date=01.08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24858802 |full-text-url=https://sci-hub.do/10.1016/j.bcp.2014.05.009 }} * {{medline-title |title=Fullerenol protects retinal pigment epithelial cells from oxidative stress-induced premature senescence via activating [[SIRT1]]. |date=20.05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24845634 |full-text-url=https://sci-hub.do/10.1167/iovs.13-13732 }} * {{medline-title |title=Essential role for the TRF2 telomere protein in adult skin homeostasis. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24725274 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326939 }} * {{medline-title |title=Wild-type p53-induced phosphatase 1 (Wip1) forestalls cellular premature senescence at physiological oxygen levels by regulating DNA damage response signaling during DNA replication. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24552809 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984300 }} * {{medline-title |title=Molecular characterization of collaborator of ARF ([[CARF]]) as a DNA damage response and cell cycle checkpoint regulatory protein. |date=01.04.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24485912 |full-text-url=https://sci-hub.do/10.1016/j.yexcr.2014.01.022 }} * {{medline-title |title=The thyroid hormone receptor β induces DNA damage and premature senescence. |date=06.01.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24395638 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882795 }} * {{medline-title |title=Novel delivery system for T-oligo using a nanocomplex formed with an alpha helical peptide for melanoma therapy. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24391441 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879016 }} * {{medline-title |title=Dysfunction of endothelial progenitor cells from smokers and chronic obstructive pulmonary disease patients due to increased DNA damage and senescence. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23897750 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377082 }} * {{medline-title |title=Maternal embryonic leucine zipper kinase ([[MELK]]) reduces replication stress in glioblastoma cells. |date=16.08.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23836907 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745365 }} * {{medline-title |title=Epigenetic silencing mediates mitochondria stress-induced longevity. |date=04.06.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23747251 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694503 }} * {{medline-title |title=Changes in splicing factor expression are associated with advancing age in man. |date=09.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23747814 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863542 }} * {{medline-title |title=The role of [[ATM]] and DNA damage in neurons: upstream and downstream connections. |date=08.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23680599 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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23502677 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632461 }} * {{medline-title |title=Impairment of [[BRCA1]]-related DNA double-strand break repair leads to ovarian aging in mice and humans. |date=13.02.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23408054 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130338 }}
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