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Aging genes 80-89
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__NOTOC__ * [[Aging genes 300|Genes with 300 and more publications]] * [[Aging genes 200-299|Genes with 200-299 publications]] * [[Aging genes 100-199|Genes with 100-199 publications]] * [[Aging genes 90-99|Genes with 90-99 publications]] * [[Aging genes 80-89|Genes with 80-89 publications]] * [[Aging genes 70-79|Genes with 70-79 publications]] * [[Aging genes 60-69|Genes with 60-69 publications]] * [[Aging genes 50-59|Genes with 50-59 publications]] * [[Aging genes 40-49|Genes with 40-49 publications]] * [[Aging genes 30-39|Genes with 30-39 publications]] * [[Aging genes 20-29|Genes with 20-29 publications]] * [[Aging genes 10-19|Genes with 10-19 publications]] * [[Aging genes 5-9|Genes with 5-9 publications]] * [[Aging genes 3-4|Genes with 3-4 publications]] * [[Aging genes 1-2|Genes with 1-2 publications]] * [[Aging_genes_A-Z_table]] ==AR== * {{medline-title |title=Mechanisms of Androgen Receptor Agonist- and Antagonist-Mediated Cellular Senescence in Prostate Cancer. |date=08.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32650419 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408918 }} * {{medline-title |title=Interleukin-23 Represses the Level of Cell Senescence Induced by the Androgen Receptor Antagonists Enzalutamide and Darolutamide in Castration-Resistant Prostate Cancer Cells. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32562083 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335377 }} * {{medline-title |title=A Landscape of Murine Long Non-Coding RNAs Reveals the Leading Transcriptome Alterations in Adipose Tissue during Aging. |date=26.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32460027 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603645 }} * {{medline-title |title=Senolytic compounds control a distinct fate of androgen receptor agonist- and antagonist-induced cellular senescent LNCaP prostate cancer cells. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32351687 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183592 }} * {{medline-title |title=Accelerated aging of rice by controlled microwave treatment. |date=18.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32339762 |full-text-url=https://sci-hub.do/10.1016/j.foodchem.2020.126853 }} * {{medline-title |title=Role of gut microbiota in sex- and diet-dependent metabolic disorders that lead to early mortality of androgen receptor-deficient male mice. |date=01.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32017595 |full-text-url=https://sci-hub.do/10.1152/ajpendo.00461.2019 }} * {{medline-title |title=A jaboticaba extract prevents prostatic damage associated with aging and high-fat diet intake. |date=26.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32003372 |full-text-url=https://sci-hub.do/10.1039/c9fo02621e }} * {{medline-title |title=[[TGFB1]]-Mediated Gliosis in Multiple Sclerosis Spinal Cords Is Favored by the Regionalized Expression of [[HOXA5]] and the Age-Dependent Decline in Androgen Receptor Ligands. |date=26.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31779094 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928867 }} * {{medline-title |title=Identifying blood-specific age-related DNA methylation markers on the Illumina MethylationEPIC® BeadChip. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31546163 |full-text-url=https://sci-hub.do/10.1016/j.forsciint.2019.109944 }} * {{medline-title |title=Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging. |date=05.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31303548 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739444 }} * {{medline-title |title=Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing. |date=18.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31320667 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639311 }} * {{medline-title |title=Enhanced beta-1 adrenergic receptor responsiveness in coronary arterioles following intravenous stromal vascular fraction therapy in aged rats. |date=11.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31296794 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660031 }} * {{medline-title |title=Older Adults Exhibit Greater Visual Cortex Inhibition and Reduced Visual Cortex Plasticity Compared to Younger Adults. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31249506 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582629 }} * {{medline-title |title=Loss of Prefrontal Cortical Higher Cognition with Uncontrollable Stress: Molecular Mechanisms, Changes with Age, and Relevance to Treatment. |date=17.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31108855 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562841 }} * {{medline-title |title=Study on neuroendocrine-immune function of Phenylethanoid Glycosides of Desertliving Cistanche herb in perimenopausal rat model. |date=28.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30995546 |full-text-url=https://sci-hub.do/10.1016/j.jep.2019.111884 }} * {{medline-title |title=Vitamin D3 mediated regulation of steroidogenesis mitigates testicular activity in an aged rat model. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30923019 |full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2019.03.016 }} * {{medline-title |title=Androgens Ameliorate Impaired Ischemia-Induced Neovascularization Due to Aging in Male Mice. |date=01.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30830222 |full-text-url=https://sci-hub.do/10.1210/en.2018-00951 }} * {{medline-title |title=Halogen-substituted anthranilic acid derivatives provide a novel chemical platform for androgen receptor antagonists. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30615932 |full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2018.12.005 }} * {{medline-title |title=ERK mediated survival signaling is dependent on the Gq-G-protein coupled receptor type and subcellular localization in adult cardiac myocytes. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30528765 |full-text-url=https://sci-hub.do/10.1016/j.yjmcc.2018.11.020 }} * {{medline-title |title=Impaired enzymatic reactive aldehyde-detoxifying capacity and glutathione peroxidase activity in the aged human arterial tissue. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30472277 |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.013 }} * {{medline-title |title=Androgen Receptor in Neurons Slows Age-Related Cortical Thinning in Male Mice. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30496619 |full-text-url=https://sci-hub.do/10.1002/jbmr.3625 }} * {{medline-title |title=The presbycardia phenotype: Cardiac remodeling and valvular degeneration in nonagenarians. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30431175 |full-text-url=https://sci-hub.do/10.1111/echo.14160 }} * {{medline-title |title=The androgen receptor is required for maintenance of bone mass in adult male mice. |date=05.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30308267 |full-text-url=https://sci-hub.do/10.1016/j.mce.2018.10.008 }} * {{medline-title |title=Sympathetic neurotransmission in spleens from aging Brown-Norway rats subjected to reduced sympathetic tone. |date=15.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30195094 |full-text-url=https://sci-hub.do/10.1016/j.jneuroim.2018.08.010 }} * {{medline-title |title=Assessment of the Aging of the Brown Adipose Tissue by F-FDG PET/CT Imaging in the Progeria Mouse Model Lmna . |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30116163 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079616 }} * {{medline-title |title=Staging of amyloid β, t-tau, regional atrophy rates, and cognitive change in a nondemented cohort: Results of serial mediation analyses. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29984299 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031152 }} * {{medline-title |title=Aging of human alpha rhythm. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29920435 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.05.018 }} * {{medline-title |title=Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction. |date=01.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809168 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063498 }} * {{medline-title |title=Dexmedetomidine attenuates renal fibrosis via α2-adrenergic receptor-dependent inhibition of cellular senescence after renal ischemia/reperfusion. |date=15.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29729264 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2018.05.003 }} * {{medline-title |title=Cross talk between androgen and Wnt signaling potentially contributes to age-related skeletal muscle atrophy in rats. |date=01.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29722624 |full-text-url=https://sci-hub.do/10.1152/japplphysiol.00768.2017 }} * {{medline-title |title=Increase in random component of heart rate variability coinciding with developmental and degenerative stages of life. |date=25.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29693554 |full-text-url=https://sci-hub.do/10.1088/1361-6579/aac007 }} * {{medline-title |title=Relationship between morphological development and sex hormone receptor expression of mammary glands with age in male rats. |date=30.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29526866 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083026 }} * {{medline-title |title=Altered expression of hepatic β-adrenergic receptors in aging rats: implications for age-related metabolic dysfunction in liver. |date=01.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29212811 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712558 }} * {{medline-title |title=Reproductive aging in male dogs: The epididymal sperm defects and expression of androgen receptor in reproductive tissues. |date=01.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29197295 |full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2017.11.011 }} * {{medline-title |title=Iron status and oxidative stress in the aged rabbit heart. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29180047 |full-text-url=https://sci-hub.do/10.1016/j.yjmcc.2017.11.016 }} * {{medline-title |title=Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063982 |full-text-url=https://sci-hub.do/10.1007/s10571-017-0557-2 }} * {{medline-title |title=Impact of HPV vaccination: health gains in the Italian female population. |date=29.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28962572 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622511 }} * {{medline-title |title=The prevalence and progression of mild cognitive impairment among clinic and community populations: a systematic review and meta-analysis. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28884657 |full-text-url=https://sci-hub.do/10.1017/S1041610217000473 }} * {{medline-title |title=Age-related changes in sexual function and steroid-hormone receptors in the medial preoptic area of male rats. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28882473 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722693 }} * {{medline-title |title=Amalaki rasayana, a traditional Indian drug enhances cardiac mitochondrial and contractile functions and improves cardiac function in rats with hypertrophy. |date=17.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28819266 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561106 }} * {{medline-title |title=The biological and clinical advances of androgen receptor function in age-related diseases and cancer [Review]. |date=28.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28824023 |full-text-url=https://sci-hub.do/10.1507/endocrj.EJ17-0328 }} * {{medline-title |title=Local Allergic Rhinitis in Adult Patients with Chronic Nasal Symptoms. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28787729 |full-text-url=https://sci-hub.do/10.1159/000478656 }} * {{medline-title |title=Effect of Suo Quan Wan on the bladder function of aging rats based on the β-adrenoceptor. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28587421 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450672 }} * {{medline-title |title=Effect of early life physical growth on midlife vertebral dimensions - The Northern Finland Birth Cohort 1966 study. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28479496 |full-text-url=https://sci-hub.do/10.1016/j.bone.2017.05.006 }} * {{medline-title |title=Estrogen receptor β, a regulator of androgen receptor signaling in the mouse ventral prostate. |date=09.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28439009 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441728 }} * {{medline-title |title=Gonad-related factors promote muscle performance gain during postnatal development in male and female mice. |date=01.07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28351832 |full-text-url=https://sci-hub.do/10.1152/ajpendo.00446.2016 }} * {{medline-title |title=Inter-Regional Variations in Gene Expression and Age-Related Cortical Thinning in the Adolescent Brain. |date=01.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28334178 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093352 }} * {{medline-title |title=Glutathione metabolic status in the aged rabbit aorta. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28188813 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.02.003 }} * {{medline-title |title=The link between vascular dysfunction, bladder ischemia, and aging bladder dysfunction. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28042309 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167073 }} * {{medline-title |title=Expression of β1- and β2-adrenergic receptors in the lungs and changes in the levels of corresponding autoantibodies in an aged rat model of heart failure. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27779651 |full-text-url=https://sci-hub.do/10.3892/ijmm.2016.2786 }} * {{medline-title |title=Anabolic resistance assessed by oral stable isotope ingestion following bed rest in young and older adult volunteers: Relationships with changes in muscle mass. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27742138 |full-text-url=https://sci-hub.do/10.1016/j.clnu.2016.09.019 }} * {{medline-title |title=ADP-Induced Ca Signaling and Proliferation of Rat Ventricular Myofibroblasts Depend on Phospholipase C-Linked TRP Channels Activation Within Lipid Rafts. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27755650 |full-text-url=https://sci-hub.do/10.1002/jcp.25656 }} * {{medline-title |title=Structural and Histochemical Alterations in the Aortic Valves of Elderly Patients: A Comparative Study of Aortic Stenosis, Aortic Regurgitation, and Normal Valves. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27747234 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056004 }} * {{medline-title |title=Preventive effects of dexmedetomidine on the development of cognitive dysfunction following systemic inflammation in aged rats. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27738803 |full-text-url=https://sci-hub.do/10.1007/s00540-016-2264-4 }} * {{medline-title |title=Autosomal recessive brachyolmia: early radiological findings. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27544198 |full-text-url=https://sci-hub.do/10.1007/s00256-016-2458-8 }} * {{medline-title |title=Morphological and molecular aspects of immobilization-induced muscle atrophy in rats at different stages of postnatal development: the role of autophagy. |date=01.09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27445301 |full-text-url=https://sci-hub.do/10.1152/japplphysiol.00687.2015 }} * {{medline-title |title=The Long-Term Outcome of Boys With Partial Androgen Insensitivity Syndrome and a Mutation in the Androgen Receptor Gene. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27403927 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095251 }} * {{medline-title |title=Exacerbated cardiac fibrosis induced by β-adrenergic activation in old mice due to decreased AMPK activity. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27389807 |full-text-url=https://sci-hub.do/10.1111/1440-1681.12622 }} * {{medline-title |title=The activation of [[OR51E1]] causes growth suppression of human prostate cancer cells. |date=26.07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27374083 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217014 }} * {{medline-title |title=Role of androgens in dhea-induced rack1 expression and cytokine modulation in monocytes. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27239218 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884617 }} * {{medline-title |title=Aging up-regulates [[AR]]A55 in stromal cells, inducing androgen-mediated prostate cancer cell proliferation and migration. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27178620 |full-text-url=https://sci-hub.do/10.1007/s10735-016-9679-y }} * {{medline-title |title=Serum allergen-specific IgE, allergic rhinitis severity, and age. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27119121 |full-text-url=https://sci-hub.do/10.4193/Rhin15.300 }} * {{medline-title |title=The tumor suppressor [[ING1]]b is a novel corepressor for the androgen receptor and induces cellular senescence in prostate cancer cells. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26993046 |full-text-url=https://sci-hub.do/10.1093/jmcb/mjw007 }} * {{medline-title |title=β2-Adrenergic receptor ablation modulates hepatic lipid accumulation and glucose tolerance in aging mice. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26952573 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.03.005 }} * {{medline-title |title=Pubertal exposure to ethinylestradiol promotes different effects on the morphology of the prostate of the male and female gerbil during aging. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26945824 |full-text-url=https://sci-hub.do/10.1002/tox.22252 }} * {{medline-title |title=Changes in rat testis morphology and androgen receptor expression around the age of puberty. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26854979 |full-text-url=https://sci-hub.do/10.1016/j.aanat.2016.01.003 }} * {{medline-title |title=Prenatal exposure to ethinylestradiol alters the morphologic patterns and increases the predisposition for prostatic lesions in male and female gerbils during ageing. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26852889 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840244 }} * {{medline-title |title=Testosterone enables growth and hypertrophy in fusion impaired myoblasts that display myotube atrophy: deciphering the role of androgen and IGF-I receptors. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26538344 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889645 }} * {{medline-title |title=The interaction of serum testosterone levels and androgen receptor CAG repeat polymorphism on the risk of erectile dysfunction in aging Taiwanese men. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26216079 |full-text-url=https://sci-hub.do/10.1111/andr.12068 }} * {{medline-title |title=Developing a DNA methylation assay for human age prediction in blood and bloodstain. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25979242 |full-text-url=https://sci-hub.do/10.1016/j.fsigen.2015.05.007 }} * {{medline-title |title=Suppression of induced but not developmental apoptosis in Drosophila by Ayurvedic Amalaki Rasayana and Rasa-Sindoor. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25963257 |full-text-url=https://sci-hub.do/10.1007/s12038-015-9521-9 }} * {{medline-title |title=Effects of long-term resveratrol-induced [[SIRT1]] activation on insulin and apoptotic signalling in aged skeletal muscle. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25959421 |full-text-url=https://sci-hub.do/10.1007/s00592-015-0767-3 }} * {{medline-title |title=Hypothalamic expression of oestrogen receptor α and androgen receptor is sex-, age- and region-dependent in mice. |date=04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25599767 |full-text-url=https://sci-hub.do/10.1111/jne.12258 }} * {{medline-title |title=Species differences in androgen receptor expression in the medial preoptic and anterior hypothalamic areas of adult male and female rodents. |date=22.01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25446364 |full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2014.11.003 }} * {{medline-title |title=β-Adrenergic receptor blockade impairs coronary exercise hyperemia in young men but not older men. |date=15.11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25239806 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233304 }} * {{medline-title |title=Testosterone increases renal anti-aging klotho gene expression via the androgen receptor-mediated pathway. |date=01.12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25163025 |full-text-url=https://sci-hub.do/10.1042/BJ20140739 }} * {{medline-title |title=Aging impairs VEGF-mediated, androgen-dependent regulation of angiogenesis. |date=09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25058601 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154238 }} * {{medline-title |title=Augmented reality cues to assist older drivers with gap estimation for left-turns. |date=10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24950128 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104258 }} * {{medline-title |title=Cytomegalovirus infection after acute rejection therapy in seropositive kidney transplant recipients. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24810355 |full-text-url=https://sci-hub.do/10.1111/tid.12227 }} * {{medline-title |title=Antiangiogenic and finasteride therapies: responses of the prostate microenvironment in elderly mice. |date=13.06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24792519 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2014.04.027 }} * {{medline-title |title=Distinct roles of age and abdominal visceral fat in reducing androgen receptor-dependent negative feedback on LH secretion in healthy men. |date=07.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24782426 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069241 }} * {{medline-title |title=Pectinase-treated Panax ginseng extract (GINST) rescues testicular dysfunction in aged rats via redox-modulating proteins. |date=05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24594315 |full-text-url=https://sci-hub.do/10.1016/j.exger.2014.02.012 }} * {{medline-title |title=Differential impact of the expression of the androgen receptor by age in estrogen receptor-positive breast cancer. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24403250 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892381 }} * {{medline-title |title=Prostatic microenvironment in senescence: fibroblastic growth factors × hormonal imbalance. |date=05.2014 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|title=The effect of five kinds of surface treatment agents on the bond strength to various ceramics with thermocycle aging. |date=29.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28701640 |full-text-url=https://sci-hub.do/10.4012/dmj.2016-383 }} * {{medline-title |title=Diffusion-weighted magnetic resonance imaging in the assessment of choroid plexus aging. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28644061 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602337 }} * {{medline-title |title=Prenatal ethanol exposure modifies locomotor activity and induces selective changes in Met-enk expression in adolescent rats. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27889070 |full-text-url=https://sci-hub.do/10.1016/j.npep.2016.11.006 }} * {{medline-title |title=Fatigue and its relationship with physical activity, age, and body composition in adults with cerebral palsy. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27861776 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{{medline-title |title=Effects of chronic exposure to 950 MHz ultra-high-frequency electromagnetic radiation on reactive oxygen species metabolism in the right and left cerebral cortex of young rats of different ages. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26272641 |full-text-url=https://sci-hub.do/10.3109/09553002.2015.1083629 }} * {{medline-title |title=Broiler responses to digestible threonine at different ages: a neural networks approach. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26249314 |full-text-url=https://sci-hub.do/10.1111/jpn.12373 }} * {{medline-title |title=Effect of feeding guanidinoacetic acid and L-arginine on the fertility rate and sperm penetration in the perivitelline layer of aged broiler breeder hens. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26216477 |full-text-url=https://sci-hub.do/10.1111/jpn.12372 }} * {{medline-title |title=Does low serum TSH within the normal range have negative impact on physical exercise 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|title=Senescence Reprogramming by [[TIMP1]] Deficiency Promotes Prostate Cancer Metastasis. |date=26.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33186519 |full-text-url=https://sci-hub.do/10.1016/j.ccell.2020.10.012 }} * {{medline-title |title=Alterations in Mitochondrial Dynamic-related Genes in the Peripheral Blood of Alzheimer's Disease Patients. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33023448 |full-text-url=https://sci-hub.do/10.2174/1567205017666201006162538 }} * {{medline-title |title=Data mining of human plasma proteins generates a multitude of highly predictive aging clocks that reflect different aspects of aging. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33031577 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681068 }} * {{medline-title |title=Human ESC-sEVs alleviate age-related bone loss by rejuvenating senescent bone marrow-derived mesenchymal stem cells. |date=10.08.2020 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{{medline-title |title=Loss of [[PTEN]] induces lung fibrosis via alveolar epithelial cell senescence depending on NF-κB activation. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30548445 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351835 }} * {{medline-title |title=Increased susceptibility of aging gastric mucosa to injury and delayed healing: Clinical implications. |date=14.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30479459 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235800 }} * {{medline-title |title=[[PRKN]]-regulated mitophagy and cellular senescence during COPD pathogenesis. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30290714 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351145 }} * {{medline-title |title=[[MCL1]] gene silencing promotes senescence and apoptosis of glioma cells via inhibition of the PI3K/Akt signaling pathway. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30296359 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|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607034 }} * {{medline-title |title=[[PTEN]] in cancer, metabolism, and aging. |date=04.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23245767 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836169 }} ==SIRT6== * {{medline-title |title=Association between [[SIRT6]] Methylation and Human Longevity in a Chinese Population. |date=25.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33238266 |full-text-url=https://sci-hub.do/10.1159/000508832 }} * {{medline-title |title=Sirtuin 6 deficiency induces endothelial cell senescence via downregulation of forkhead box M1 expression. |date=10.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33171439 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695388 }} * {{medline-title |title=Melatonin and Sirtuins in Buccal Epithelium: Potential Biomarkers of Aging and Age-Related Pathologies. |date=30.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143333 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662974 }} * {{medline-title |title=The [[SIRT6]] activator MDL-800 improves genomic stability and pluripotency of old murine-derived iPS cells. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33089974 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431819 }} * {{medline-title |title=Sirtuins as Possible Predictors of Aging and Alzheimer's Disease Development: Verification in the Hippocampus and Saliva. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33098511 |full-text-url=https://sci-hub.do/10.1007/s10517-020-04986-4 }} * {{medline-title |title=[[FGFR4]] Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer. |date=14.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066597 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602396 }} * {{medline-title |title=The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32919015 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111090 }} * {{medline-title |title=Intrinsic Type 1 Interferon (IFN1) Profile of Uncultured Human Bone Marrow CD45 CD271 Multipotential Stromal Cells (BM-[[MSC]]s): The Impact of Donor Age, Culture Expansion and IFNα and IFNβ Stimulation. |date=15.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32679782 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399891 }} * {{medline-title |title=Age-related epigenetic drift deregulates [i][[SIRT6]][/i] expression and affects its downstream genes in human peripheral blood mononuclear cells. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32573339 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678931 }} * {{medline-title |title=[[SIRT6]] mono-ADP ribosylates [[KDM2A]] to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair. |date=25.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32584788 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343504 }} * {{medline-title |title=Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators. |date=07.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32518153 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415977 }} * {{medline-title |title=Age-dependent role of [[SIRT6]] in jawbone via regulating senescence and autophagy of bone marrow stromal cells. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32002721 |full-text-url=https://sci-hub.do/10.1007/s10735-020-09857-w }} * {{medline-title |title=The effect of high glucose on the biological characteristics of nucleus pulposus-derived mesenchymal stem cells. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31957071 |full-text-url=https://sci-hub.do/10.1002/cbf.3441 }} * {{medline-title |title=Mechanism of activation for the sirtuin 6 protein deacylase. |date=31.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31822559 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996886 }} * {{medline-title |title=Sirtuin 6 deficiency transcriptionally up-regulates TGF-β signaling and induces fibrosis in mice. |date=10.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31744885 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956532 }} * {{medline-title |title=Proteomics of Long-Lived Mammals. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31737995 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117992 }} * {{medline-title |title=Sirtuins and [[SIRT6]] in Carcinogenesis and in Diet. |date=07.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31591350 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801518 }} * {{medline-title |title=Plasma exosomes in OSA patients promote endothelial senescence: effect of long-term adherent continuous positive airway pressure. |date=13.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31552414 |full-text-url=https://sci-hub.do/10.1093/sleep/zsz217 }} * {{medline-title |title=[[SIRT6]]-mediated transcriptional suppression of MALAT1 is a key mechanism for endothelial to mesenchymal transition. |date=15.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31399301 |full-text-url=https://sci-hub.do/10.1016/j.ijcard.2019.07.082 }} * {{medline-title |title=[[SIRT6]] Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. |date=18.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31002797 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499390 }} * {{medline-title |title=[[SIRT6]] participates in the quality control of aged oocytes via modulating telomere function. |date=29.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30926765 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deposition induced by metabolic disorder. |date=18.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30227388 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188481 }} * {{medline-title |title=MiR-125b attenuates human hepatocellular carcinoma malignancy through targeting [[SIRT6]]. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30034937 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048406 }} * {{medline-title |title=Role of accelerated aging in limb muscle wasting of patients with COPD. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29970961 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022820 }} * {{medline-title |title=A Review of the Recent Advances Made with [[SIRT6]] and its Implications on Aging Related Processes, Major Human Diseases, and Possible Therapeutic Targets. |date=29.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966233 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164879 }} * {{medline-title |title=Application of multivariate longitudinal models in [[SIRT6]], FBS, and BMI analysis of the elderly. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29901417 |full-text-url=https://sci-hub.do/10.1080/13685538.2018.1477933 }} * {{medline-title |title=Sirtuins in Renal Health and Disease. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29712732 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050939 }} * {{medline-title |title=Boosting [[ATM]] activity alleviates aging and extends lifespan in a mouse model of progeria. |date=02.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29717979 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957528 }} * {{medline-title |title=High expression of CPT1b in skeletal muscle in metabolically healthy older subjects. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29657112 |full-text-url=https://sci-hub.do/10.1016/j.diabet.2018.01.018 }} * {{medline-title |title=Haploinsufficiency of [i]Trp53[/i] dramatically extends the lifespan of Sirt6-deficient mice. |date=23.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29474172 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825207 }} * {{medline-title |title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 }} * {{medline-title |title=Stem Cells and Progenitors in Human Peripheral Blood Get Activated by Extremely Active Resveratrol (XAR™). |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177909 |full-text-url=https://sci-hub.do/10.1007/s12015-017-9784-7 }} * {{medline-title |title=Aging as an Epigenetic Phenomenon. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081695 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635645 }} * {{medline-title |title=Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28767699 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540417 }} * {{medline-title |title=[[SIRT1]] and [[SIRT6]] Signaling Pathways in Cardiovascular Disease Protection. |date=10.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28661724 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824538 }} * {{medline-title |title=Ursolic Acid Mediates Hepatic Protection through Enhancing of anti-aging Biomarkers. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28558631 |full-text-url=https://sci-hub.do/10.2174/1874609810666170531103140 }} * {{medline-title |title=Characterization of physiological defects in adult [[SIRT6]]-/- mice. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28448551 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407791 }} * {{medline-title |title=Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts. |date=01.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28385812 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495944 }} * {{medline-title |title=[[SIRT6]] polymorphism rs117385980 is associated with longevity and healthy aging in Finnish men. |date=11.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28399814 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387321 }} * {{medline-title |title=Neuroprotective Functions for the Histone Deacetylase [[SIRT6]]. |date=28.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28355558 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389893 }} * {{medline-title |title=Cosmeceutical product consisting of biomimetic peptides: antiaging effects in vivo and in vitro. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28123310 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234555 }} * {{medline-title |title=Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27882448 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357501 }} * {{medline-title |title=[[SIRT6]]: Novel Mechanisms and Links to Aging and Disease. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27836583 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326594 }} * {{medline-title |title=Multiple pathways of [[SIRT6]] at the crossroads in the control of longevity, cancer, and cardiovascular diseases. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27829173 |full-text-url=https://sci-hub.do/10.1016/j.arr.2016.10.008 }} * {{medline-title |title=[[SIRT6]] delays cellular senescence by promoting p27Kip1 ubiquitin-proteasome degradation. |date=16.09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27794562 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115890 }} * {{medline-title |title=The protein-interaction network with functional roles in tumorigenesis, neurodegeneration, and aging. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27699588 |full-text-url=https://sci-hub.do/10.1007/s11010-016-2836-5 }} * {{medline-title |title=[[SIRT6]] Overexpression Improves Various Aspects of Mouse Healthspan. |date=01.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27519885 |full-text-url=https://sci-hub.do/10.1093/gerona/glw152 }} * {{medline-title |title=Slowing ageing by design: the rise of NAD and sirtuin-activating compounds. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27552971 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107309 }} * {{medline-title |title=Ursolic acid regulates aging process through enhancing of metabolic sensor proteins level. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27470332 |full-text-url=https://sci-hub.do/10.1016/j.biopha.2016.04.047 }} * {{medline-title |title=Ergothioneine oxidation in the protection against high-glucose induced endothelial senescence: Involvement of [[SIRT1]] and [[SIRT6]]. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27101740 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2016.04.013 }} * {{medline-title |title=Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins. |date=15.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27038700 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.03.015 }} * {{medline-title |title=AMPK/Snf1 signaling regulates histone acetylation: Impact on gene expression and epigenetic functions. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27010499 |full-text-url=https://sci-hub.do/10.1016/j.cellsig.2016.03.009 }} * {{medline-title |title=Calorie restriction-induced [[SIRT6]] activation delays aging by suppressing NF-κB signaling. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26940461 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889297 }} * {{medline-title |title=Sirtuins, Cell Senescence, and Vascular Aging. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26948035 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848124 }} * {{medline-title |title=Lack of association between polymorphisms in the [[SIRT6]] gene and longevity in a Chinese population. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26802595 |full-text-url=https://sci-hub.do/10.1016/j.mcp.2016.01.005 }} * {{medline-title |title=[[SIRT6]], oxidative stress, and aging. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26780861 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746614 }} * {{medline-title |title=Sirt6 regulates dendritic cell differentiation, maturation, and function. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26761436 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761712 }} * {{medline-title |title=The complex role of [[SIRT6]] in carcinogenesis. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26717993 |full-text-url=https://sci-hub.do/10.1093/carcin/bgv167 }} * {{medline-title |title=The expression levels of the sirtuins in patients with BCC. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26631040 |full-text-url=https://sci-hub.do/10.1007/s13277-015-4522-8 }} * {{medline-title |title=Localization of sirtuins ([[SIRT1]]-7) in the aged mouse inner ear. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26472659 |full-text-url=https://sci-hub.do/10.3109/00016489.2015.1093172 }} * {{medline-title |title=Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26471901 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792692 }} * {{medline-title |title=Are sirtuins markers of ovarian aging? |date=10.01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26403315 |full-text-url=https://sci-hub.do/10.1016/j.gene.2015.09.043 }} * {{medline-title |title=Sirtuin-dependent clock control: new advances in metabolism, aging and cancer. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26335311 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610809 }} * {{medline-title |title=[[SIRT6]]/NF-κB signaling axis in ginsenoside Rg1-delayed hematopoietic stem/progenitor cell senescence. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26191269 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503140 }} * {{medline-title |title=Differential expression of sirtuins in the aging rat brain. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26005404 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424846 }} * {{medline-title |title=Scopoletin has a potential activity for anti-aging via autophagy in human lung fibroblasts. |date=15.03.2015 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{{medline-title |title=Toll-like receptor 4 differentially regulates adult hippocampal neurogenesis in an age- and sex-dependent manner. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32343455 |full-text-url=https://sci-hub.do/10.1002/hipo.23209 }} * {{medline-title |title=Aerobic Training Down-Regulates Pentraxin 3 and Pentraxin 3/Toll-Like Receptor 4 Ratio, Irrespective of Oxidative Stress Response, in Elderly Subjects. |date=27.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32012711 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070734 }} * {{medline-title |title=Aging-associated immunosenescence via alterations in splenic immune cell populations in rat. |date=15.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31838133 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.117168 }} * {{medline-title |title=Leptin induces immunosenescence in human B cells. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31831137 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002206 }} * {{medline-title |title=Cellular senescence induced by [[S100A9]] in mesenchymal stromal cells through [[NLRP3]] inflammasome activation. |date=14.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31727865 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874461 }} * {{medline-title |title=Biomarkers for vascular ageing in aorta tissues and blood samples. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31648011 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110741 }} * {{medline-title |title=Accelerated decline in cognition in a mouse model of increased oxidative stress. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31641924 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885085 }} * {{medline-title |title=Genetic Variation in the Magnitude and Longevity of the IgG Subclass Response to a Diphtheria-Tetanus-Acellular Pertussis (DTaP) Vaccine in Mice. |date=20.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31547158 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963843 }} * {{medline-title |title=Rapamycin improves sevoflurane‑induced cognitive dysfunction in aged rats by mediating autophagy through the [[TLR4]]/MyD88/NF‑κB signaling pathway. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31432123 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755174 }} * {{medline-title |title=Targeting [[HMGB1]] by ethyl pyruvate ameliorates systemic lupus erythematosus and reverses the senescent phenotype of bone marrow-mesenchymal stem cells. |date=14.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31303606 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660056 }} * {{medline-title |title=Age-dependent effect between [[MARCO]] and [[TLR4]] on PMMA particle phagocytosis by macrophages. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225947 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653467 }} * {{medline-title |title=Regulation of Toll-Like Receptor (TLR) Signaling Pathway by Polyphenols in the Treatment of Age-Linked Neurodegenerative Diseases: Focus on [[TLR4]] Signaling. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31134076 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522942 }} * {{medline-title |title=[[TLR4]] Promotes and DAP12 Limits Obesity-Induced Osteoarthritis in Aged Female Mice. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31044181 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478583 }} * {{medline-title |title=Novel Chitohexaose Analog Protects Young and Aged mice from CLP Induced Polymicrobial Sepsis. |date=27.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30814582 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393422 }} * {{medline-title |title=Endothelial toll-like receptor 4 maintains lung integrity via epigenetic suppression of p16 . |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30790400 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516428 }} * {{medline-title |title=Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30659954 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.016 }} * {{medline-title |title=Aging leads to dysfunctional innate immune responses to [[TLR2]] and [[TLR4]] agonists. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30402800 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504629 }} * {{medline-title |title=Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30128650 |full-text-url=https://sci-hub.do/10.1007/s12035-018-1307-2 }} * {{medline-title |title=Ablation of toll-like receptor 4 attenuates aging-induced myocardial remodeling and contractile dysfunction through NCoRI-[[HDAC1]]-mediated regulation of autophagy. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29660306 |full-text-url=https://sci-hub.do/10.1016/j.yjmcc.2018.04.009 }} * {{medline-title |title=Cryopreserved whole blood for the quantification of monocyte, T-cell and NK-cell subsets, and monocyte receptor expression by multi-color flow cytometry: A methodological study based on participants from the canadian longitudinal study on aging. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29624852 |full-text-url=https://sci-hub.do/10.1002/cyto.a.23372 }} * {{medline-title |title=Inflammation, insulin signaling and cognitive function in aged APP/PS1 mice. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29604345 |full-text-url=https://sci-hub.do/10.1016/j.bbi.2018.03.032 }} * {{medline-title |title=Repeated stimulation by LPS promotes the senescence of DPSCs via [[TLR4]]/MyD88-NF-κB-p53/p21 signaling. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29480340 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021280 }} * {{medline-title |title=Ageing potentiates diet-induced glucose intolerance, β-cell failure and tissue inflammation through [[TLR4]]. |date=09.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29426925 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807311 }} * {{medline-title |title=Fibronectin Containing Extra Domain A Induces Plaque Destabilization in the Innominate Artery of Aged Apolipoprotein E-Deficient Mice. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29326316 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823768 }} * {{medline-title |title=Granzyme A in Human Platelets Regulates the Synthesis of Proinflammatory Cytokines by Monocytes in Aging. |date=01.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29167233 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736423 }} * {{medline-title |title=[[TLR4]] and [[TLR2]] activation is differentially associated with age during Parkinson's disease. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29077524 |full-text-url=https://sci-hub.do/10.1080/08820139.2017.1379024 }} * {{medline-title |title=Toll-like receptor 4 ([[TLR4]]) deficient mice are protected from adipose tissue inflammation in aging. |date=07.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28898202 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636669 }} * {{medline-title |title=Role of pattern recognition receptors of the neurovascular unit in inflamm-aging. |date=01.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28801521 |full-text-url=https://sci-hub.do/10.1152/ajpheart.00106.2017 }} * {{medline-title |title=Exenatide mitigated diet-induced vascular aging and atherosclerotic plaque growth in ApoE-deficient mice under chronic stress. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28734203 |full-text-url=https://sci-hub.do/10.1016/j.atherosclerosis.2017.07.014 }} * {{medline-title |title=Human Monocyte Subsets Are Transcriptionally and Functionally Altered in Aging in Response to Pattern Recognition Receptor Agonists. |date=15.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28696254 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548610 }} * {{medline-title |title=A dual agonist of farnesoid X receptor (FXR) and the G protein-coupled receptor TGR5, INT-767, reverses age-related kidney disease in mice. |date=21.07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28596381 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519354 }} * {{medline-title |title=The critical role played by endotoxin-induced liver autophagy in the maintenance of lipid metabolism during sepsis. |date=03.07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28575583 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529074 }} * {{medline-title |title=Growth performance, reproductive traits and offspring survivability of genetically modified rams overexpressing toll-like receptor 4. |date=01.07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28532825 |full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2017.04.006 }} * {{medline-title |title=Increased dipeptidyl peptidase-4 accelerates diet-related vascular aging and atherosclerosis in ApoE-deficient mice under chronic stress. |date=15.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28549747 |full-text-url=https://sci-hub.do/10.1016/j.ijcard.2017.05.062 }} * {{medline-title |title=Age-related changes and distribution of T cell markers (CD3 and [[CD4]]) and toll-like receptors(TLR2, [[TLR3]],[[TLR4]] and [[TLR7]]) in the duck lymphoid organs. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28356195 |full-text-url=https://sci-hub.do/10.1016/j.imbio.2017.01.004 }} * {{medline-title |title=Aging and amyloid β oligomers enhance [[TLR4]] expression, LPS-induced Ca responses, and neuron cell death in cultured rat hippocampal neurons. |date=31.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28143556 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282876 }} * {{medline-title |title=Attenuated recovery of contractile function in aging hearts following global ischemia/reperfusion: Role of extracellular HSP27 and [[TLR4]]. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28079228 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5263054 }} * {{medline-title |title=Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27845246 |full-text-url=https://sci-hub.do/10.1016/j.bbalip.2016.11.003 }} * {{medline-title |title=Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization. |date=01.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27793997 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386828 }} * {{medline-title |title=Strain-dependent response to stimulation in middle-aged rat macrophages: A quest after a useful indicator of healthy aging. |date=01.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27756630 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.10.005 }} * {{medline-title |title=Microglial response to LPS increases in wild-type mice during aging but diminishes in an Alzheimer's mouse model: Implication of [[TLR4]] signaling in disease progression. |date=14.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27641666 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048480 }} * {{medline-title |title=Aging increases the susceptibility of hepatic inflammation, liver fibrosis and aging in response to high-fat diet in mice. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27578257 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061686 }} * {{medline-title |title=Modulation of Macrophage Polarization and [[HMGB1]]-TLR2/[[TLR4]] Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27070323 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829159 }} * {{medline-title |title=In vitro cytokine induction by TLR-activating vaccine adjuvants in human blood varies by age and adjuvant. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27081760 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906944 }} * {{medline-title |title=Effects of aerobic training on markers of autophagy in the elderly. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26940016 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005904 }} * {{medline-title |title=Reduced levels of cytosolic DNA sensor [[AIM2]] are associated with impaired cytokine responses in healthy elderly. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26944367 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.02.016 }} * {{medline-title |title=Bone biology-related gingival transcriptome in ageing and periodontitis in non-human primates. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26859687 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844783 }} * {{medline-title |title=Gut microbiota lipopolysaccharide accelerates inflamm-aging in mice. |date=16.01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26772806 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715324 }} * {{medline-title |title=Direct Regulation of [[TLR5]] Expression by Caveolin-1. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26615831 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697003 }} * {{medline-title |title=Anti-Inflamm-Aging Effects of Long-Term Caloric Restriction via Overexpression of [[SIGIRR]] to Inhibit NF-κB Signaling Pathway. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26431348 |full-text-url=https://sci-hub.do/10.1159/000430248 }} * {{medline-title |title=Lead exposure induced microgliosis and astrogliosis in hippocampus of young mice potentially by triggering [[TLR4]]-MyD88-NFκB signaling cascades. |date=03.12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26386401 |full-text-url=https://sci-hub.do/10.1016/j.toxlet.2015.09.015 }} * {{medline-title |title=Monocyte Phenotype and Polyfunctionality Are Associated With Elevated Soluble Inflammatory Markers, Cytomegalovirus Infection, and Functional and Cognitive Decline in Elderly Adults. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26286603 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007736 }} * {{medline-title |title=Flagellin-dependent [[TLR5]]/caveolin-1 as a promising immune activator in immunosenescence. |date=10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26223660 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* {{medline-title |title=Aging does not affect the ability of human monocyte-derived dendritic cells to phagocytose Candida albicans. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25783173 |full-text-url=https://sci-hub.do/10.1007/s40520-015-0344-1 }} * {{medline-title |title=Aging oppositely affects [[TNF]]-α and IL-10 production by macrophages from different rat strains. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25009084 |full-text-url=https://sci-hub.do/10.1007/s10522-014-9513-4 }} * {{medline-title |title=Bacteria and Toll-like receptor and cytokine mRNA expression profiles associated with canine arthritis. |date=15.08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24856731 |full-text-url=https://sci-hub.do/10.1016/j.vetimm.2014.04.004 }} * {{medline-title |title=Elevated muscle [[TLR4]] expression and metabolic endotoxemia in human aging. |date=02.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24846769 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311182 }} * {{medline-title |title=Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24779584 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326942 }} * {{medline-title |title=Hip fracture aggravates systemic inflammation and lung injury in aged chronic cigarette smoke exposed rats. |date=01.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24115247 |full-text-url=https://sci-hub.do/10.1002/jor.22491 }} * {{medline-title |title=Carbocysteine regulates innate immune responses and senescence processes in cigarette smoke stimulated bronchial epithelial cells. |date=25.11.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24076166 |full-text-url=https://sci-hub.do/10.1016/j.toxlet.2013.09.013 }} * {{medline-title |title=Dendritic cells from the elderly display an intrinsic defect in the production of IL-10 in response to lithium chloride. |date=11.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23988651 |full-text-url=https://sci-hub.do/10.1016/j.exger.2013.08.006 }} * {{medline-title |title=[Effects of total paeony glucosides on mRNA expressions of Toll receptors and interleukin-33 in the brain tissue of D-galactose induced aging rats: an experimental research]. |date=06.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23980368 }} * {{medline-title |title=Short-term bed rest increases [[TLR4]] and IL-6 expression in skeletal muscle of older adults. |date=01.08.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23761639 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743002 }} * {{medline-title |title=Microglia express distinct M1 and M2 phenotypic markers in the postnatal and adult central nervous system in male and female mice. |date=09.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23686747 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715560 }} * {{medline-title |title=Repairing DNA damage by [[XRCC6]]/KU70 reverses [[TLR4]]-deficiency-worsened HCC development via restoring senescence and autophagic flux. |date=01.06.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23518600 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672303 }} ==CGA== * {{medline-title |title=Safety and efficacy of preoperative chemoradiotherapy in fit older patients with intermediate or locally advanced rectal cancer evaluated by comprehensive geriatric assessment: A planned interim analysis of a multicenter, phase II trial. |date=04.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33160954 |full-text-url=https://sci-hub.do/10.1016/j.jgo.2020.10.016 }} * {{medline-title |title=The Protective Effect of Chlorogenic Acid on Vascular Senescence via the Nrf2/HO-1 Pathway. |date=25.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32630570 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350250 }} * {{medline-title |title=Association between comprehensive geriatric assessment and short-term outcomes among older adult patients with stroke: A nationwide retrospective cohort study using propensity score and instrumental variable methods. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32566923 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298723 }} * {{medline-title |title=Interventions to Improve Clinical Outcomes in Older Adults Admitted to a Surgical Service: A Systematic Review and Meta-analysis. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32417101 |full-text-url=https://sci-hub.do/10.1016/j.jamda.2020.03.023 }} * {{medline-title |title=A Computerized Frailty Assessment Tool at Points-of-Care: Development of a Standalone Electronic Comprehensive Geriatric Assessment/Frailty Index (eFI-[[CGA]]). |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32296673 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137764 }} * {{medline-title |title=Allocating patients to geriatric medicine wards in a tertiary university hospital in England: A service evaluation of the Specialist Advice for the Frail Elderly (SAFE) team. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31942488 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880728 }} * {{medline-title |title=Role of Frailty on Risk Stratification in Cardiac Surgery and Procedures. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31894551 |full-text-url=https://sci-hub.do/10.1007/978-3-030-33330-0_11 }} * {{medline-title |title=Developing an objective structured clinical examination in comprehensive geriatric assessment - A pilot study. |date=05-08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31745004 |full-text-url=https://sci-hub.do/10.4103/efh.EfH_111_18 }} * {{medline-title |title=How do doctors choose treatment for older gynecological cancer patients? A Japanese Gynecologic Oncology Group survey of gynecologic oncologists. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31728682 |full-text-url=https://sci-hub.do/10.1007/s10147-019-01574-z }} * {{medline-title |title=Validation of the Pictorial Fit-Frail Scale in a memory clinic setting. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31524122 |full-text-url=https://sci-hub.do/10.1017/S1041610219000905 }} * {{medline-title |title=Impact of Resolution of Hyponatremia on Neurocognitive and Motor Performance in Geriatric Patients. |date=29.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31467370 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715723 }} * {{medline-title |title=Health outcome of older hospitalized patients in internal medicine environments evaluated by Identification of Seniors at Risk (ISAR) screening and geriatric assessment. |date=14.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31412787 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694685 }} * {{medline-title |title=What will perioperative geriatric assessment for older cancer patients look like in 2025? Advantages and limitations of new technologies in geriatric assessment. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31371102 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374764 }} * {{medline-title |title=Impact of comprehensive geriatric assessment on short-term mortality in older patients with cancer-a follow-up study. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31163339 |full-text-url=https://sci-hub.do/10.1016/j.ejca.2019.05.003 }} * {{medline-title |title=Comprehensive Geriatric Assessment in the perioperative setting; where next? |date=01.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31147709 |full-text-url=https://sci-hub.do/10.1093/ageing/afz069 }} * {{medline-title |title=Use of comprehensive geriatric assessment ([[CGA]]) to define frailty in geriatric oncology: Searching for the best threshold. Cross-sectional study of 418 old patients with cancer evaluated in the Geriatric Frailty Clinic (G.F.C.) of Toulouse (France). |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30956134 |full-text-url=https://sci-hub.do/10.1016/j.jgo.2019.03.011 }} * {{medline-title |title=The prognostic significance of geriatric syndromes and resources. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30911909 |full-text-url=https://sci-hub.do/10.1007/s40520-019-01168-9 }} * {{medline-title |title=Functional status in a geriatric oncology setting: A review. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30824222 |full-text-url=https://sci-hub.do/10.1016/j.jgo.2019.02.004 }} * {{medline-title |title=Changes in the Use of Comprehensive Geriatric Assessment in Clinical Trials for Older Patients with Cancer over Time. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30710065 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693722 }} * {{medline-title |title=Predictive values of two frailty screening tools in older patients with solid cancer: a comparison of SAOP2 and G8. |date=12.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30416679 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205549 }} * {{medline-title |title=New associations of the Multidimensional Prognostic Index. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30406302 |full-text-url=https://sci-hub.do/10.1007/s00391-018-01471-6 }} * {{medline-title |title=Is care based on comprehensive geriatric assessment with mobile teams better than usual care? 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An umbrella review. |date=01.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29206906 |full-text-url=https://sci-hub.do/10.1093/ageing/afx166 }} * {{medline-title |title=[Geriatric assessment and prognostic scores in older cancer patient: Additional support to the therapeutic decision?] |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29150094 |full-text-url=https://sci-hub.do/10.1016/j.bulcan.2017.10.004 }} * {{medline-title |title=Preadmission Functional Decline Predicts Functional Improvement Among Older Patients Admitted to Acute Care Hospital. |date=11.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29087448 |full-text-url=https://sci-hub.do/10.1093/gerona/glx211 }} * {{medline-title |title=Towards a biological geriatric assessment. |date=01.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28964828 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.017 }} * {{medline-title |title=The potential clinical benefits of medicines optimisation through comprehensive geriatric assessment, carried out by secondary care geriatricians, in a general practice care setting in North Staffordshire, UK: a feasibility study. |date=28.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28963282 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640128 }} * {{medline-title |title=New horizons in comprehensive geriatric assessment. |date=01.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28874007 |full-text-url=https://sci-hub.do/10.1093/ageing/afx104 }} * {{medline-title |title=Acute geriatrics at the front door. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28765414 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297644 }} * {{medline-title |title=Assessment and management of radiotherapy induced toxicity in older patients. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28739158 |full-text-url=https://sci-hub.do/10.1016/j.jgo.2017.07.001 }} * {{medline-title |title=Hospital-at-home Integrated Care Programme for the management of disabling health crises in older patients: comparison with bed-based Intermediate Care. |date=01.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28655169 |full-text-url=https://sci-hub.do/10.1093/ageing/afx099 }} * {{medline-title |title=Arginine [[CGA]] codons as a source of nonsense mutations: a possible role in multivariant gene expression, control of mRNA quality, and aging. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28523359 |full-text-url=https://sci-hub.do/10.1007/s00438-017-1328-y }} * {{medline-title |title=The growing challenge of major trauma in older people: a role for comprehensive geriatric assessment? |date=01.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28338866 |full-text-url=https://sci-hub.do/10.1093/ageing/afx035 }} * {{medline-title |title=Modeling individual and relative accuracy of screening tools in geriatric oncology. |date=01.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28327973 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834042 }} * {{medline-title |title=[Geriatric inpatients with iron deficiency-associated Restless Legs Syndrome. A retrospective analysis]. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28244024 |full-text-url=https://sci-hub.do/10.1007/s15006-017-9294-1 }} * {{medline-title |title=Frailty affects the initial treatment response and time to recovery of mobility in acutely ill older adults admitted to hospital. |date=01.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28104595 |full-text-url=https://sci-hub.do/10.1093/ageing/afw257 }} * {{medline-title |title=Three Decades of Comprehensive Geriatric Assessment: Evidence Coming From Different Healthcare Settings and Specific Clinical Conditions. |date=01.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28049616 |full-text-url=https://sci-hub.do/10.1016/j.jamda.2016.11.004 }} * {{medline-title |title=Interventions to prevent or reduce the level of frailty in community-dwelling older adults: a scoping review of the literature and international policies. |date=01.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28064173 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405756 }} * {{medline-title |title=Can consultant geriatrician led comprehensive geriatric assessment in the emergency department reduce hospital admission rates? A systematic review. |date=01.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27940568 |full-text-url=https://sci-hub.do/10.1093/ageing/afw231 }} * {{medline-title |title=Assessment of frailty in aged dogs. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27901392 |full-text-url=https://sci-hub.do/10.2460/ajvr.77.12.1357 }} * {{medline-title |title=Asymptomatic and yet C. difficile-toxin positive? Prevalence and risk factors of carriers of toxigenic Clostridium difficile among geriatric in-patients. |date=15.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27846818 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111236 }} * {{medline-title |title=Palliative Care of Cancer in the Older Patient. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27812859 |full-text-url=https://sci-hub.do/10.1007/s11912-016-0557-2 }} * {{medline-title |title=Comprehensive geriatric assessment: recognition of identified geriatric conditions by community-dwelling older persons. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27614077 |full-text-url=https://sci-hub.do/10.1093/ageing/afw157 }} * {{medline-title |title=Frailty as determined by a comprehensive geriatric assessment-derived deficit-accumulation index in older patients with cancer who receive chemotherapy. |date=15.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27529755 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|title=Neuroticism predicts all-cause mortality over 19-years: The moderating effects on functional status, and the angiotensin-converting enzyme. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29764603 |full-text-url=https://sci-hub.do/10.1016/j.jpsychores.2018.04.013 }} * {{medline-title |title=Adverse Childhood Experiences among a Community of Resilient Centenarians and Seniors: Implications for a Chronic Disease Prevention Framework. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29702049 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922855 }} * {{medline-title |title=Adverse Childhood Experiences and Young Adult Health Outcomes Among Youth Aging Out of Foster Care. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29709622 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035089 }} * {{medline-title |title=Sex differences in transcriptomic profiles in aged kidney cells of renin lineage. |date=18.04.2018 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* {{medline-title |title=Type 1 diabetes in older adults: Comparing treatments and chronic complications in the United States T1D Exchange and the German/Austrian DPV registries. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27764721 |full-text-url=https://sci-hub.do/10.1016/j.diabres.2016.09.024 }} * {{medline-title |title=Association of adverse childhood experiences with lifetime mental and substance use disorders among men and women aged 50 years. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27780491 |full-text-url=https://sci-hub.do/10.1017/S1041610216001800 }} * {{medline-title |title=Bioactive peptides in beef: Endogenous generation through postmortem aging. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27710773 |full-text-url=https://sci-hub.do/10.1016/j.meatsci.2016.09.015 }} * {{medline-title |title=Angiotensin-Converting Enzyme Inhibitors and Parameters of Sarcopenia: Relation to Muscle Mass, Strength and Function: Data from the Berlin 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Nigeria: A cross sectional study. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25810358 |full-text-url=https://sci-hub.do/10.1002/pbc.25503 }} * {{medline-title |title=Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53. |date=03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25790137 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366240 }} * {{medline-title |title=Cognitive frailty, a novel target for the prevention of elderly dependency. |date=03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25555677 |full-text-url=https://sci-hub.do/10.1016/j.arr.2014.12.004 }} * {{medline-title |title=Attention capacity and self-report of subjective cognitive decline: a P3 ERP study. |date=12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25204705 |full-text-url=https://sci-hub.do/10.1016/j.biopsycho.2014.08.016 }} * {{medline-title |title=Cold hypersensitivity increases with age in mice with sickle cell disease. 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