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Aging genes 60-99
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__NOTOC__ * [[Aging genes 100|Genes with 100 and more publications]] * [[Aging genes 60-99|Genes with 60-99 publications]] * [[Aging genes 30-59|Genes with 30-59 publications]] * [[Aging genes 10-29|Genes with 10-29 publications]] * [[Aging genes 3-9|Genes with 3-9 publications]] * [[Aging genes 1-2|Genes with 1-2 publications]] ==CD28== * {{medline-title |title=Premature CD4 T Cells Senescence Induced by Chronic Infection in Patients with Acute Coronary Syndrome. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33269101 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673853 }} * {{medline-title |title=The IMMENSE Study: The Interplay Between iMMune and ENdothelial Cells in Mediating Cardiovascular Risk in Systemic Lupus Erythematosus. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33193356 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658008 }} * {{medline-title |title=Emergence of T cell immunosenescence in diabetic chronic kidney disease. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33088331 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574244 }} * {{medline-title |title=The relationship between Chlamydia pneumoniae infection and CD4/CD8 ratio, lymphocyte subsets in middle-aged and elderly individuals. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33068732 |full-text-url=https://sci-hub.do/10.1016/j.micpath.2020.104541 }} * {{medline-title |title=Next steps in mechanisms of inflammaging. |date=22.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32960694 |full-text-url=https://sci-hub.do/10.1080/15548627.2020.1822089 }} * {{medline-title |title=A randomized pilot trial to evaluate the benefit of the concomitant use of atorvastatin and Raltegravir on immunological markers in protease-inhibitor-treated subjects living with HIV. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32941476 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498036 }} * {{medline-title |title=Aging affects responsiveness of peripheral blood mononuclear cells to immunosuppression of periodontal ligament stem cells. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32663414 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364836 }} * {{medline-title |title=Comparison of Donepezil, Memantine, Melatonin, and Liuwei Dihuang Decoction on Behavioral and Immune Endocrine Responses of Aged Senescence-Accelerated Mouse Resistant 1 Mice. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32477103 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241684 }} * {{medline-title |title=Immunosenescent characteristics of T cells in young patients following haploidentical haematopoietic stem cell transplantation from parental donors. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32280463 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142179 }} * {{medline-title |title=Diagnosis-independent loss of T-cell costimulatory molecules in individuals with cytomegalovirus infection. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32209361 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594105 }} * {{medline-title |title=Accelerated immunosenescence in rheumatoid arthritis: impact on clinical progression. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32190092 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068869 }} * {{medline-title |title=Accelerated immune aging was correlated with lupus-associated brain fog in reproductive-age systemic lupus erythematosus patients. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32107852 |full-text-url=https://sci-hub.do/10.1111/1756-185X.13816 }} * {{medline-title |title=T cells, aging and senescence. |date=22.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32092501 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110887 }} * {{medline-title |title=Liver fibrosis and accelerated immune dysfunction (immunosenescence) among HIV-infected Russians with heavy alcohol consumption - an observational cross-sectional study. |date=31.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31892306 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938606 }} * {{medline-title |title=Effect of Allogenic Bone Marrow Mesenchymal Stem Cell Transplantation on T Cells of Old Mice. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31895587 |full-text-url=https://sci-hub.do/10.1089/cell.2019.0055 }} * {{medline-title |title=Peripheral antibody concentrations are associated with highly differentiated T cells and inflammatory processes in the human bone marrow. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31462901 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706884 }} * {{medline-title |title=Collaboration of [[MYC]] and [[RUNX2]] in lymphoma simulates T-cell receptor signaling and attenuates p53 pathway activity. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31257681 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772115 }} * {{medline-title |title=The Evolving Role of CD8 [[CD28]] Immunosenescent T Cells in Cancer Immunology. |date=08.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31181772 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600236 }} * {{medline-title |title=Are skin senescence and immunosenescence linked within individuals? |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31062498 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612632 }} * {{medline-title |title=Expanded peripheral [[CD4]] [[CD28]] T cells and its association with atherosclerotic changes in patients with end stage renal disease on hemodialysis. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30853362 |full-text-url=https://sci-hub.do/10.1016/j.humimm.2019.03.008 }} * {{medline-title |title=Impact of aging on inflammatory and immune responses during elastin peptide-induced murine emphysema. |date=01.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30675803 |full-text-url=https://sci-hub.do/10.1152/ajplung.00402.2018 }} * {{medline-title |title=Low DNA damage in peripheral lymphocytes of healthy elderly individuals with inverted CD4:CD8 ratio. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30599400 |full-text-url=https://sci-hub.do/10.1016/j.intimp.2018.12.060 }} * {{medline-title |title=Post-thymic [[CD4]] positive cytotoxic T cell infiltrates of the skin: A clinical and histomorphologic spectrum of the unique [[CD4]] positive T cell of immunosenescence. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30572149 |full-text-url=https://sci-hub.do/10.1016/j.anndiagpath.2018.10.010 }} * {{medline-title |title=Immune Response-Dependent Assembly of IMP Dehydrogenase Filaments. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30555474 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283036 }} * {{medline-title |title=Reduced expression of the lncRNA NRON is a potential hallmark of the CMV-amplified CD8 T cell accumulations commonly seen in older humans. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30415066 |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.004 }} * {{medline-title |title=Low IL-2 Expressing T Cells in Thalassemia Major Patients: Is It Immune Aging. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30369736 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186253 }} * {{medline-title |title=[[CD28]] pro-atherogenic [[CD4]] T-cells explain the link between CMV infection and an increased risk of cardiovascular death. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30214635 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134924 }} * {{medline-title |title=Senescence markers: Predictive for response to checkpoint inhibitors. |date=01.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30151962 |full-text-url=https://sci-hub.do/10.1002/ijc.31763 }} * {{medline-title |title=An imbalance in the T-helper phenotypes displayed by senescent [[CD4]] [[CD28]] T cells is associated with erosive arthritis (rhupus syndrome) in systemic lupus erythematosus. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30111238 |full-text-url=https://sci-hub.do/10.1177/0961203318793715 }} * {{medline-title |title=Features of Immunosenescence in Women Newly Diagnosed With Breast Cancer. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30061900 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055359 }} * {{medline-title |title=Innate and adaptive immune dysregulation in critically ill ICU patients. |date=05.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29976949 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033948 }} * {{medline-title |title=Is Chronic Exposure to Low-Dose Organochlorine Pesticides a New Risk Factor of T-cell Immunosenescence? |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29991517 |full-text-url=https://sci-hub.do/10.1158/1055-9965.EPI-17-0799 }} * {{medline-title |title=Involvement of MicroRNAs in the Aging-Related Decline of [[CD28]] Expression by Human T Cells. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29967621 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015875 }} * {{medline-title |title=Older men display elevated levels of senescence-associated exercise-responsive [[CD28]] angiogenic T cells compared with younger men. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29939490 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016626 }} * {{medline-title |title=Multi-color flow cytometry for evaluating age-related changes in memory lymphocyte subsets in dogs. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29859828 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197816 }} * {{medline-title |title=Abnormalities of age-related T cell senescence in Parkinson's disease. |date=28.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29807534 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972443 }} * {{medline-title |title=CD57 identifies T cells with functional senescence before terminal differentiation and relative telomere shortening in patients with activated [[PI3]] kinase delta syndrome. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29790605 |full-text-url=https://sci-hub.do/10.1111/imcb.12169 }} * {{medline-title |title=Low cytomegalovirus seroprevalence in early multiple sclerosis: a case for the 'hygiene hypothesis'? |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29528545 |full-text-url=https://sci-hub.do/10.1111/ene.13622 }} * {{medline-title |title=Senescent T-Cells Promote Bone Loss in Rheumatoid Arthritis. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29472917 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810289 }} * {{medline-title |title=T-cell Immunoglobulin and ITIM Domain Contributes to CD8 T-cell Immunosenescence. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29349889 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847879 }} * {{medline-title |title=Signal transduction changes in [[CD4]] and CD8 T cell subpopulations with aging. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29307735 |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.01.005 }} * {{medline-title |title=Increased senescent CD8 T cells in the peripheral blood mononuclear cells of Behçet's disease patients. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29255925 |full-text-url=https://sci-hub.do/10.1007/s00403-017-1802-8 }} * {{medline-title |title=Immune parameters associated with mortality in the elderly are context-dependent: lessons from Sweden, Holland and Belgium. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29185165 |full-text-url=https://sci-hub.do/10.1007/s10522-017-9739-z }} * {{medline-title |title=T-cell differentiation and CD56 levels in polypoidal choroidal vasculopathy and neovascular age-related macular degeneration. |date=20.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29165313 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723695 }} * {{medline-title |title=[Effects of serums containing Buzhong Yiqi decoction with Astragalus Radix or Hedysari Radix on anti-immunosenescence in spleen lymphocytes of SAMP8 mice]. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28914034 |full-text-url=https://sci-hub.do/10.4268/cjcmm20161524 }} * {{medline-title |title=Arterial Stiffness Is Associated With Cytomegalovirus-Specific Senescent CD8 T Cells. |date=28.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847915 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634298 }} * {{medline-title |title=Human endogenous retrovirus HERV-K(HML-2) env expression is not associated with markers of immunosenescence. |date=15.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28774724 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.07.019 }} * {{medline-title |title=Assessing inflammageing. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28768292 |full-text-url=https://sci-hub.do/10.1097/MCO.0000000000000391 }} * {{medline-title |title=Immunosenescence Induced by Plasma from Individuals with Obesity Caused Cell Signaling Dysfunction and Inflammation. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28707376 |full-text-url=https://sci-hub.do/10.1002/oby.21888 }} * {{medline-title |title=Increased IL-15 Production and Accumulation of Highly Differentiated CD8 Effector/Memory T Cells in the Bone Marrow of Persons with Cytomegalovirus. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28674537 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474847 }} * {{medline-title |title=Structural characterization of a pectic polysaccharide from Codonopsis pilosula and its immunomodulatory activities in vivo and in vitro. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28600205 |full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2017.06.023 }} * {{medline-title |title=Impact of age and cytomegalovirus on CD8 T-cell compartment remodeling after solid organ transplantation: A one-year follow-up study. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28465043 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.04.011 }} * {{medline-title |title=Long-term calorie restriction in humans is not associated with indices of delayed immunologic aging: A descriptive study. |date=31.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28447069 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389018 }} * {{medline-title |title=Novel Senescent Regulatory T-Cell Subset with Impaired Suppressive Function in Rheumatoid Arthritis. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28373873 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357868 }} * {{medline-title |title=Melatonin: Antioxidant and modulatory properties in age-related changes during Trypanosoma cruzi infection. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28370218 |full-text-url=https://sci-hub.do/10.1111/jpi.12409 }} * {{medline-title |title=Consumption of green tea epigallocatechin-3-gallate enhances systemic immune response, antioxidative capacity and HPA axis functions in aged male swiss albino mice. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28341876 |full-text-url=https://sci-hub.do/10.1007/s10522-017-9696-6 }} * {{medline-title |title=Lymph node and circulating T cell characteristics are strongly correlated in end-stage renal disease patients, but highly differentiated T cells reside within the circulation. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28142201 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383449 }} * {{medline-title |title=Therapeutic effect of human ghrelin and growth hormone: Attenuation of immunosuppression in septic aged rats. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28115288 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519455 }} * {{medline-title |title=Mechanisms Underlying T Cell Immunosenescence: Aging and Cytomegalovirus Infection. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28082969 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5186782 }} * {{medline-title |title=The influences of age on T lymphocyte subsets in C57BL/6 mice. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28053579 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198989 }} * {{medline-title |title=Adaptive Memory of Human NK-like CD8 T-Cells to Aging, and Viral and Tumor Antigens. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28066426 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165258 }} * {{medline-title |title="Inflamm-aging" influences immune cell survival factors in human bone marrow. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27995612 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434810 }} * {{medline-title |title=Circulating T Cells of Patients with Nijmegen Breakage Syndrome Show Signs of Senescence. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28000062 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325864 }} * {{medline-title |title=Phenotypic characteristics of aged [[CD4]] [[CD28]] T lymphocytes are determined by changes in the whole-genome DNA methylation pattern. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28026094 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334526 }} * {{medline-title |title=Age-related changes in the gene expression profile of antigen-specific mouse CD8 T cells can be partially reversed by blockade of the BTLA/[[CD160]] pathways during vaccination. |date=09.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27922818 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270668 }} * {{medline-title |title=Effects of Physical Exercise on Markers of Cellular Immunosenescence: A Systematic Review. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27866236 |full-text-url=https://sci-hub.do/10.1007/s00223-016-0212-9 }} * {{medline-title |title=Immunosenescence-Related Transcriptomic and Immunologic Changes in Older Individuals Following Influenza Vaccination. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27853459 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089977 }} * {{medline-title |title=T cells in multiple myeloma display features of exhaustion and senescence at the tumor site. |date=03.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27809856 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093947 }} * {{medline-title |title=Steroid resistance in COPD is associated with impaired molecular chaperone Hsp90 expression by pro-inflammatory lymphocytes. |date=21.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27769261 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075183 }} * {{medline-title |title=Impact of aging on host immune response and survival in melanoma: an analysis of 3 patient cohorts. |date=19.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27760559 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070187 }} * {{medline-title |title=Pharmacological advantages of melatonin in immunosenescence by improving activity of T lymphocytes. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27533940 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946322 }} * {{medline-title |title=T Cells Going Innate. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27402226 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633931 }} * {{medline-title |title=Effects of Heavy Drinking on T-Cell Phenotypes Consistent with Immunosenescence in Untreated HIV Infection. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27388907 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070699 }} * {{medline-title |title=Inflammatory and immune markers associated with physical frailty syndrome: findings from Singapore longitudinal aging studies. |date=17.05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27119508 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045356 }} * {{medline-title |title=Alteration of T Cell Subtypes in Beta-Thalassaemia Major: Impact of Ferritin Level. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27042462 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800527 }} * {{medline-title |title=Aging of immune system: Immune signature from peripheral blood lymphocyte subsets in 1068 healthy adults. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26886066 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931839 }} * {{medline-title |title=PTSD is associated with an increase in aged T cell phenotypes in adults living in Detroit. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26894484 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826331 }} * {{medline-title |title=Genetic Influence on the Peripheral Blood [[CD4]] T-cell Differentiation Status in CMV Infection. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26755680 |full-text-url=https://sci-hub.do/10.1093/gerona/glv230 }} * {{medline-title |title=Shifts in subsets of CD8 T-cells as evidence of immunosenescence in patients with cancers affecting the lungs: an observational case-control study. |date=28.12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26711627 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692066 }} * {{medline-title |title=Biomarkers related to immunosenescence: relationships with therapy and survival in lung cancer patients. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26589409 |full-text-url=https://sci-hub.do/10.1007/s00262-015-1773-6 }} * {{medline-title |title=Poor survival in glioblastoma patients is associated with early signs of immunosenescence in the [[CD4]] T-cell compartment after surgery. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26405601 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570117 }} * {{medline-title |title=Aging-associated subpopulations of human CD8 T-lymphocytes identified by their [[CD28]] and CD57 phenotypes. |date=11-12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26277688 |full-text-url=https://sci-hub.do/10.1016/j.archger.2015.08.007 }} * {{medline-title |title=Senescent profile of angiogenic T cells from systemic lupus erythematosus patients. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26232454 |full-text-url=https://sci-hub.do/10.1189/jlb.5HI0215-042R }} * {{medline-title |title=Cardio-metabolic and immunological impacts of extra virgin olive oil consumption in overweight and obese older adults: a randomized controlled trial. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26251666 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527272 }} * {{medline-title |title=CD4⁺[[CD28]]null T lymphocytes resemble CD8⁺[[CD28]]null T lymphocytes in their responses to IL-15 and IL-21 in HIV-infected patients. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26034206 |full-text-url=https://sci-hub.do/10.1189/jlb.1A0514-276RR }} * {{medline-title |title=Activation-induced and damage-induced cell death in aging human T cells. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25843236 |full-text-url=https://sci-hub.do/10.1016/j.mad.2015.03.011 }} * {{medline-title |title=The impact of immunosenescence on humoral immune response variation after influenza A/H1N1 vaccination in older subjects. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25816015 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|full-text-url=https://sci-hub.do/10.1016/S0004-9514(14)60422-0 }} * {{medline-title |title=Amyloid-beta transporter expression at the choroid plexus in normal aging: the possibility of reduced resistance to oxidative stress insults. |date=25.04.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24777406 }} * {{medline-title |title=Randomized phase II trial comparing carboplatin plus weekly paclitaxel and docetaxel alone in elderly patients with advanced non-small cell lung cancer: north japan lung cancer group trial 0801. |date=04.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24682465 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983823 }} ==ATM== * {{medline-title |title=S[[ATM]]F Suppresses the Premature Senescence Phenotype of the [[ATM]] Loss-of-Function Mutant and Improves Its Fertility in [i]Arabidopsis[/i]. |date=30.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143308 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662627 }} * {{medline-title |title=[[ATM]] mediated-p53 signaling pathway forms a novel axis for senescence control. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32949791 |full-text-url=https://sci-hub.do/10.1016/j.mito.2020.09.002 }} * {{medline-title |title=Non-canonical [[ATM]]/MRN activities temporally define the senescence secretory program. |date=05.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32785991 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534619 }} * {{medline-title |title=[[ATM]] is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging. |date=22.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32201398 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138542 }} * {{medline-title |title=[[ATM]] suppresses leaf senescence triggered by DNA double-strand break through epigenetic control of senescence-associated genes in Arabidopsis. |date=07.2020 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HIV-Infected Individuals on Antiretroviral Therapy. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31781094 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856652 }} * {{medline-title |title=SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31565865 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850945 }} * {{medline-title |title=LncRNA RP11-670E13.6, interacted with hnRNPH, delays cellular senescence by sponging microRNA-663a in UVB damaged dermal fibroblasts. |date=23.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31444317 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738423 }} * {{medline-title |title=Tel1/[[ATM]] Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31391264 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accelerated senescence. |date=01.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31189537 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633392 }} * {{medline-title |title=Meeting report of the 14th Japan-Korea joint symposium on cancer and aging research: current status of translational research and approaches to precision medicine. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30859317 |full-text-url=https://sci-hub.do/10.1007/s00432-019-02887-2 }} * {{medline-title |title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287 }} * {{medline-title |title=Alleviation of Senescence via [[ATM]] Inhibition in Accelerated Aging Models. |date=31.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30726661 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449716 }} * {{medline-title |title=Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence. |date=01.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30735837 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2019.02.005 }} * {{medline-title |title=Genomic insult oriented mitochondrial instability and proliferative hindrance in the bone marrow of aplastic mice including stem/progenitor population. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30683472 |full-text-url=https://sci-hub.do/10.1016/j.prp.2019.01.028 }} * {{medline-title |title=N-Myc promotes therapeutic resistance development of neuroendocrine prostate cancer by differentially regulating miR-421/[[ATM]] pathway. |date=18.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30657058 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337850 }} * {{medline-title |title=Hydrogen Indirectly Suppresses Increases in Hydrogen Peroxide in Cytoplasmic Hydroxyl Radical-Induced 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dysfunction and premature senescence of vascular cells in vivo. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29923368 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052487 }} * {{medline-title |title=Boosting [[ATM]] activity alleviates aging and extends lifespan in a mouse model of progeria. |date=02.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29717979 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957528 }} * {{medline-title |title=Inflammation, a significant player of Ataxia-Telangiectasia pathogenesis? |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29582093 |full-text-url=https://sci-hub.do/10.1007/s00011-018-1142-y }} * {{medline-title |title=Transcriptional Repression of High-Mobility Group Box 2 by p21 in Radiation-Induced Senescence. |date=30.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487276 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935093 }} * {{medline-title |title=Senescence-messaging secretome factors trigger premature senescence in human endometrium-derived stem cells. |date=19.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397942 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.01.163 }} * {{medline-title |title=Bisphenol A induces DSB-[[ATM]]-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29275510 |full-text-url=https://sci-hub.do/10.1007/s00204-017-2150-3 }} * {{medline-title |title=Global mapping of transcription factor motifs in human aging. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29293662 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749797 }} * {{medline-title |title=Ataxia-Telangiectasia Mutated Modulation of Carbon Metabolism in Cancer. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29238697 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712564 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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30873018 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403180 }} * {{medline-title |title=Neuron-targeted caveolin-1 improves neuromuscular function and extends survival in [[SOD1]] mice. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30894019 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529340 }} * {{medline-title |title=A Combination of Intrathecal and Intramuscular Application of Human Mesenchymal Stem Cells Partly Reduces the Activation of Necroptosis in the Spinal Cord of [[SOD1]] Rats. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30802001 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525562 }} * {{medline-title |title=Curcumin supplementation increases survival and lifespan in Drosophila under heat stress conditions. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30488487 |full-text-url=https://sci-hub.do/10.1002/biof.1454 }} * {{medline-title |title=[i]Lactobacillus plantarum[/i] CQPC11 Isolated from Sichuan Pickled Cabbages Antagonizes d-galactose-Induced Oxidation and Aging in Mice. |date=20.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463304 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278364 }} * {{medline-title |title=Antioxidant hesperetin improves the quality of porcine oocytes during aging in vitro. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30358012 |full-text-url=https://sci-hub.do/10.1002/mrd.23079 }} * {{medline-title |title=[[SIRT1]] deacetylase in aging-induced neuromuscular degeneration and amyotrophic lateral sclerosis. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30295421 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260920 }} * {{medline-title |title=Superoxide dismutase activity is significantly lower in end-stage osteoarthritic cartilage than non-osteoarthritic cartilage. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30222787 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in a [[SOD1]] -expressing ALS mouse model. |date=29.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29843805 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975400 }} * {{medline-title |title=Resveratrol improves in vitro maturation of oocytes in aged mice and humans. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29778389 |full-text-url=https://sci-hub.do/10.1016/j.fertnstert.2018.01.020 }} * {{medline-title |title=Onjisaponin B prevents cognitive impairment in a rat model of D-galactose-induced aging. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29329033 |full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.01.006 }} * {{medline-title |title=Riluzole does not improve lifespan or motor function in three ALS mouse models. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29221425 |full-text-url=https://sci-hub.do/10.1080/21678421.2017.1407796 }} * {{medline-title |title=Environment-transformable sequence-structure relationship: a 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|full-text-url=https://sci-hub.do/10.1089/ars.2017.7054 }} * {{medline-title |title=Circulating extracellular vesicles in the aging process: impact of aerobic exercise. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28819811 |full-text-url=https://sci-hub.do/10.1007/s11010-017-3160-4 }} * {{medline-title |title=Diversity of astroglial responses across human neurodegenerative disorders and brain aging. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28804999 |full-text-url=https://sci-hub.do/10.1111/bpa.12538 }} * {{medline-title |title=Age-associated intracellular superoxide dismutase deficiency potentiates dermal fibroblast dysfunction during wound healing. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28677217 |full-text-url=https://sci-hub.do/10.1111/exd.13404 }} * {{medline-title |title=Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice. |date=20.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28405022 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642042 }} * {{medline-title |title=Differential menopause- versus aging-induced changes in oxidative stress and circadian rhythm gene markers. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28408140 |full-text-url=https://sci-hub.do/10.1016/j.mad.2017.04.002 }} * {{medline-title |title=Superoxide dismutase 1 is positively selected to minimize protein aggregation in great apes. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28389720 |full-text-url=https://sci-hub.do/10.1007/s00018-017-2519-8 }} * {{medline-title |title=Identification of the isomer of methionine sulfoximine that extends the lifespan of the [[SOD1]] G93A mouse. |date=24.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28323087 |full-text-url=https://sci-hub.do/10.1016/j.neulet.2017.03.029 }} * {{medline-title |title=Intermittent vibration protects aged muscle from mechanical and oxidative damage under prolonged compression. |date=11.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28314562 |full-text-url=https://sci-hub.do/10.1016/j.jbiomech.2017.02.023 }} * {{medline-title |title=Anti-Aging Effect of Riboflavin Via Endogenous Antioxidant in Fruit fly Drosophila Melanogaster. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28244572 |full-text-url=https://sci-hub.do/10.1007/s12603-016-0752-8 }} * {{medline-title |title=Transforming Cytosolic Proteins into "Insoluble" and Membrane-toxic Forms Triggering Diseases/Aging by Genetic, Pathological or Environmental Factors. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28190398 |full-text-url=https://sci-hub.do/10.2174/0929866524666170209154001 }} * {{medline-title |title=Maternal obesity in the rat impairs male offspring aging of the testicular antioxidant defence system. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28063465 |full-text-url=https://sci-hub.do/10.1071/RD16277 }} * {{medline-title |title=Muscle Fibers Secrete 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|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125956 }} * {{medline-title |title=Protective Effects of Hydrogen Sulfide in the Ageing Kidney. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27882191 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108860 }} * {{medline-title |title=VAChT overexpression increases acetylcholine at the synaptic cleft and accelerates aging of neuromuscular junctions. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27713817 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050580 }} * {{medline-title |title=Endogenous macrophage migration inhibitory factor reduces the accumulation and toxicity of misfolded [[SOD1]] in a mouse model of ALS. |date=06.09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27551074 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018779 }} * {{medline-title |title=Blackberry, raspberry and black raspberry polyphenol extracts attenuate angiotensin II-induced senescence 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|date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27109910 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2016.04.024 }} * {{medline-title |title=Age-dependent changes of the antioxidant system in rat livers are accompanied by altered MAPK activation and a decline in motor signaling. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27004051 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800781 }} * {{medline-title |title=Effects of Cellular Pathway Disturbances on Misfolded Superoxide Dismutase-1 in Fibroblasts Derived from ALS Patients. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26919046 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769150 }} * {{medline-title |title=Drivers: A Biologically Contextualized, Cross-Inferential View of the Epidemiology of Neurodegenerative Disorders. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26923014 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927850 }} * {{medline-title |title=Liver specific expression of Cu/ZnSOD extends the lifespan of Sod1 null mice. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26839948 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855307 }} * {{medline-title |title=Targeting genes in insulin-associated signalling pathway, DNA damage, cell proliferation and cell differentiation pathways by tocotrienol-rich fraction in preventing cellular senescence of human diploid fibroblasts. |date=11-12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26794818 |full-text-url=https://sci-hub.do/10.7417/T.2015.1902 }} * {{medline-title |title=Loss of RAD-23 Protects Against Models of Motor Neuron Disease by Enhancing Mutant Protein Clearance. |date=21.10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26490867 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683688 }} * {{medline-title |title=Mechanisms of Muscle Denervation in Aging: Insights from a Mouse Model of Amyotrophic Lateral Sclerosis. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26425392 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567220 }} * {{medline-title |title=Age-Related Changes in Pre- and Postsynaptic Partners of the Cholinergic C-Boutons in Wild-Type and [[SOD1]]G93A Lumbar Motoneurons. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26305672 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549056 }} * {{medline-title |title=Cordyceps sinensis oral liquid prolongs the lifespan of the fruit fly, Drosophila melanogaster, by inhibiting oxidative stress. |date=10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26239097 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564082 }} * {{medline-title |title=Cranberry anthocyanin extract prolongs lifespan of fruit flies. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26159161 |full-text-url=https://sci-hub.do/10.1016/j.exger.2015.06.021 }} * {{medline-title |title=Postactivation depression of the Ia EPSP in motoneurons is reduced in both the G127X [[SOD1]] model of amyotrophic lateral sclerosis and in aged mice. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26084911 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725116 }} * {{medline-title |title=Enhanced tethered-flight duration and locomotor activity by overexpression of the human gene [[SOD1]] in Drosophila motorneurons. |date=03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25983632 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415569 }} * {{medline-title |title=Effects of a recombinant complement component [[C3]]b functional fragment α2MR (α2-macroglobulin receptor) additive on the immune response of juvenile orange-spotted grouper (Epinephelus coioides) after the exposure to cold shock challenge. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25917969 |full-text-url=https://sci-hub.do/10.1016/j.fsi.2015.04.019 }} * {{medline-title |title=Endogenous ROS levels are increased in replicative senescence in human bone marrow mesenchymal stromal cells. |date=15.05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25839657 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.03.136 }} * {{medline-title |title=A correlation of reactive oxygen species accumulation by depletion of superoxide dismutases with age-dependent impairment in the nervous system and muscles of Drosophila adults. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25801590 |full-text-url=https://sci-hub.do/10.1007/s10522-015-9570-3 }} * {{medline-title |title=Ex vivo effects of ibogaine on the activity of antioxidative enzymes in human erythrocytes. |date=22.04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25660330 |full-text-url=https://sci-hub.do/10.1016/j.jep.2015.01.037 }} * {{medline-title |title=Early-stage treatment with Withaferin A reduces levels of misfolded superoxide dismutase 1 and extends lifespan in a mouse model of amyotrophic lateral sclerosis. |date=01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25404049 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322065 }} * {{medline-title |title=Senescence marker protein-30/superoxide dismutase 1 double knockout mice exhibit increased oxidative stress and hepatic steatosis. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25003023 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081155 }} * {{medline-title |title=A major QTL on mouse chromosome 17 resulting in lifespan variability in [[SOD1]]-G93A transgenic mouse models of amyotrophic lateral sclerosis. |date=12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25008789 |full-text-url=https://sci-hub.do/10.3109/21678421.2014.932381 }} * {{medline-title |title=Phenotype of transgenic mice carrying a very low copy number of the mutant human G93A superoxide dismutase-1 gene associated with amyotrophic lateral sclerosis. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24945277 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063781 }} * {{medline-title |title=Neophobia, [[NQO1]] and [[SIRT1]] as premorbid and prodromal indicators of AD in 3xTg-AD mice. |date=01.09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24837743 |full-text-url=https://sci-hub.do/10.1016/j.bbr.2014.04.055 }} * {{medline-title |title=Increased production of mitochondrial reactive oxygen species and reduced adult life span in an insecticide-resistant strain of Anopheles gambiae. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24555527 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008687 }} * {{medline-title |title=Lifelong training preserves some redox-regulated adaptive responses after an acute exercise stimulus in aged human skeletal muscle. |date=05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24525000 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2014.02.004 }} * {{medline-title |title=Absence of superoxide dismutase activity causes nuclear DNA fragmentation during the aging process. |date=07.02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462872 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2014.01.056 }} * {{medline-title |title=Role of antioxidant enzymes in redox regulation of N-methyl-D-aspartate receptor function and memory in middle-aged rats. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24388786 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961498 }} ==SIRT3== * {{medline-title |title=[[SIRT3]] protects endothelial cells from high glucose-induced senescence and dysfunction via the p53 pathway. |date=05.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33160987 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118724 }} * {{medline-title |title=Melatonin and Sirtuins in Buccal Epithelium: Potential Biomarkers of Aging and Age-Related Pathologies. |date=30.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143333 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662974 }} * {{medline-title |title=[i][[SIRT3]][/i] Transfection of Aged Human Bone Marrow-Derived Mesenchymal Stem Cells Improves Cell Therapy-Mediated Myocardial Repair. |date=28.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32228121 |full-text-url=https://sci-hub.do/10.1089/rej.2019.2260 }} * {{medline-title |title=17β-estradiol inhibits H O -induced senescence in HUVEC cells through upregulating [[SIRT3]] expression and promoting autophagy. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32172411 |full-text-url=https://sci-hub.do/10.1007/s10522-020-09868-w }} * {{medline-title |title=CR6 interacting factor 1 deficiency induces premature senescence via [[SIRT3]] inhibition in endothelial cells. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32109515 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2020.02.017 }} * {{medline-title |title=Mitochondrial function in skeletal myofibers is controlled by a TRF2-[[SIRT3]] axis over lifetime. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31991048 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059141 }} * {{medline-title |title=Context-Dependent Roles for SIRT2 and [[SIRT3]] in Tumor Development Upon Calorie Restriction or High Fat Diet. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31970087 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960403 }} * {{medline-title |title=The yin and yang faces of the mitochondrial deacetylase sirtuin 3 in age-related disorders. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31740222 |full-text-url=https://sci-hub.do/10.1016/j.arr.2019.100983 }} * {{medline-title |title=[i]Sirt3[/i] Deficiency Shortens Life Span and Impairs Cardiac Mitochondrial Function Rescued by [i]Opa1[/i] Gene Transfer. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31269804 |full-text-url=https://sci-hub.do/10.1089/ars.2018.7703 }} * {{medline-title |title=Low-Dose Pesticide Mixture Induces Accelerated Mesenchymal Stem Cell Aging In Vitro. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30977188 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850038 }} * {{medline-title |title=[[NLRP3]]/IL1β inflammasome associated with the aging bladder triggers bladder dysfunction in female rats. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30720125 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423574 }} * {{medline-title |title=Targeted Mitochondrial COQ Delivery Attenuates Antiretroviral-Drug-Induced Senescence of Neural Progenitor Cells. |date=04.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30592424 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364271 }} * {{medline-title |title=Caffeine Protects Skin from Oxidative Stress-Induced Senescence through the Activation of Autophagy. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30555576 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276298 }} * {{medline-title |title=The pathophysiological importance and therapeutic potential of NAD' biosynthesis and mitochondrial sirtuin [[SIRT3]] in age-associated diseases. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30557475 }} * {{medline-title |title=Aging-Related Overactivity of the Angiotensin/AT1 Axis Decreases Sirtuin 3 Levels in the Substantia Nigra, Which Induces Vulnerability to Oxidative Stress and Neurodegeneration. |date=14.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30412227 |full-text-url=https://sci-hub.do/10.1093/gerona/gly259 }} * {{medline-title |title=6-gingerol ameliorates age-related hepatic steatosis: Association with regulating lipogenesis, fatty acid oxidation, oxidative stress and mitochondrial dysfunction. |date=01.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30408433 |full-text-url=https://sci-hub.do/10.1016/j.taap.2018.11.001 }} * {{medline-title |title=Sirtuins and NAD in the Development and Treatment of Metabolic and Cardiovascular Diseases. |date=14.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30355082 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206880 }} * {{medline-title |title=Moderate calorie restriction attenuates age‑associated alterations and improves cardiac function by increasing [[SIRT1]] and [[SIRT3]] expression. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30132522 |full-text-url=https://sci-hub.do/10.3892/mmr.2018.9390 }} * {{medline-title |title=Melatonin Mitigates Mitochondrial Meltdown: Interactions with [[SIRT3]]. |date=18.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30126181 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121285 }} * {{medline-title |title=Master athletes have higher miR-7, [[SIRT3]] and [[SOD2]] expression in skeletal muscle than age-matched sedentary controls. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30107294 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092475 }} * {{medline-title |title=Sirtuin3 protects aged human mesenchymal stem cells against oxidative stress and enhances efficacy of cell therapy for ischaemic heart diseases. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30091830 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201360 }} * {{medline-title |title=Sirtuins in Renal Health and Disease. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29712732 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050939 }} * {{medline-title |title=Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29654651 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052469 }} * {{medline-title |title=Physical Exercise Improves Aging-Related Changes in Angiotensin, IGF-1, [[SIRT1]], [[SIRT3]], and VEGF in the Substantia Nigra. |date=10.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659739 |full-text-url=https://sci-hub.do/10.1093/gerona/gly072 }} * {{medline-title |title=Differential gene expression of sirtuins between somatotropinomas and nonfunctioning pituitary adenomas. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29564694 |full-text-url=https://sci-hub.do/10.1007/s11102-018-0881-7 }} * {{medline-title |title=NAD supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency. |date=20.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29432159 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828618 }} * {{medline-title |title=Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29366775 |full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.01.018 }} * {{medline-title |title=Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of [[SIRT3]]. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29289557 |full-text-url=https://sci-hub.do/10.1016/j.mad.2017.12.005 }} * {{medline-title |title=Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063982 |full-text-url=https://sci-hub.do/10.1007/s10571-017-0557-2 }} * {{medline-title |title=[Protective effect of total saponins of Panax notoginseng combined with total flavonoids of epimedium on D-galactose-incuced senescence of H9c2 cell]. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28952264 |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.2017.0012 }} * {{medline-title |title=Obesity and aging diminish sirtuin 1 ([[SIRT1]])-mediated deacetylation of [[SIRT3]], leading to hyperacetylation and decreased activity and stability of [[SIRT3]]. |date=20.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28808064 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655509 }} * {{medline-title |title=miR-34a and miR-9 are overexpressed and SIRT genes are downregulated in peripheral blood mononuclear cells of aging humans. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28699360 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544174 }} * {{medline-title |title=EphB2 signaling-mediated Sirt3 expression reduces [[MSC]] senescence by maintaining mitochondrial ROS homeostasis. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28687409 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2017.07.001 }} * {{medline-title |title=Upregulation of mitochondrial NAD levels impairs the clonogenicity of SSEA1 glioblastoma tumor-initiating cells. |date=09.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28604662 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519015 }} * {{medline-title |title=Identification of tissue-specific transcriptional markers of caloric restriction in the mouse and their use to evaluate caloric restriction mimetics. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28556428 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506434 }} * {{medline-title |title=Longevity and healthy ageing genes FOXO3A and [[SIRT3]]: Serum protein marker and new road map to burst oxidative stress by Withania somnifera. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28526626 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.05.013 }} * {{medline-title |title=Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts. |date=01.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28385812 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495944 }} * {{medline-title |title=Mitochondrial Sirtuins and Molecular Mechanisms of Aging. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28285806 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713479 }} * {{medline-title |title=Melatonin and sirtuins: A "not-so unexpected" relationship. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28109165 |full-text-url=https://sci-hub.do/10.1111/jpi.12391 }} * {{medline-title |title=[[SIRT3]] mediates decrease of oxidative damage and prevention of ageing in porcine fetal fibroblasts. |date=15.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28131761 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2017.01.010 }} * {{medline-title |title=The Role of Mitochondrial Non-Enzymatic Protein Acylation in Ageing. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28033361 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199114 }} * {{medline-title |title=Melatonin improves age-induced fertility decline and attenuates ovarian mitochondrial oxidative stress in mice. |date=12.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27731402 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059725 }} * {{medline-title |title=Gardenia jasminoides extract-capped gold nanoparticles reverse hydrogen peroxide-induced premature senescence. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27693841 |full-text-url=https://sci-hub.do/10.1016/j.jphotobiol.2016.09.033 }} * {{medline-title |title=Function of the [[SIRT3]] mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative disease. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27686535 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242307 }} * {{medline-title |title=Sirtuin 3 Deregulation Promotes Pulmonary Fibrosis. |date=01.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27522058 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964739 }} * {{medline-title |title=Effects of Grape Skin Extract on Age-Related Mitochondrial Dysfunction, Memory and Life Span in C57BL/6J Mice. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27455862 |full-text-url=https://sci-hub.do/10.1007/s12017-016-8428-4 }} * {{medline-title |title=Restoration of Mitochondrial NAD Levels Delays Stem Cell Senescence and Facilitates Reprogramming of Aged Somatic Cells. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27428041 |full-text-url=https://sci-hub.do/10.1002/stem.2460 }} * {{medline-title |title=Mitochondrial Sirtuin 3 and Renal Diseases. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27362524 |full-text-url=https://sci-hub.do/10.1159/000444370 }} * {{medline-title |title=[[CD38]] Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an [[SIRT3]]-Dependent Mechanism. |date=14.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27304511 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911708 }} * {{medline-title |title=The role of mitochondrial sirtuins in health and disease. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27164052 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2016.04.197 }} * {{medline-title |title=Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins. |date=15.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27038700 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.03.015 }} * {{medline-title |title=Manganese Superoxide Dismutase Acetylation and Dysregulation, Due to Loss of [[SIRT3]] Activity, Promote a Luminal B-Like Breast Carcinogenic-Permissive Phenotype. |date=20.08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26935174 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991597 }} * {{medline-title |title=Sirtuins, Cell Senescence, and Vascular Aging. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26948035 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848124 }} * {{medline-title |title=[[SIRT3]] Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3β. |date=14.12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26667039 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760222 }} * {{medline-title |title=The expression levels of the sirtuins in patients with BCC. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26631040 |full-text-url=https://sci-hub.do/10.1007/s13277-015-4522-8 }} * {{medline-title |title=Effects of Aging and Cardiovascular Disease Risk Factors on the Expression of Sirtuins in the Human Corpus Cavernosum. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26556180 |full-text-url=https://sci-hub.do/10.1111/jsm.13035 }} * {{medline-title |title=Localization of sirtuins ([[SIRT1]]-7) in the aged mouse inner ear. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26472659 |full-text-url=https://sci-hub.do/10.3109/00016489.2015.1093172 }} * {{medline-title |title=Are sirtuins markers of ovarian aging? |date=10.01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26403315 |full-text-url=https://sci-hub.do/10.1016/j.gene.2015.09.043 }} * {{medline-title |title=The Role of Mitochondrial DNA in Mediating Alveolar Epithelial Cell Apoptosis and Pulmonary Fibrosis. |date=07.09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26370974 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613264 }} * {{medline-title |title=Sirtuin-dependent clock control: new advances in metabolism, aging and cancer. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26335311 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610809 }} * {{medline-title |title=Mitochondrial Aging and Physical Decline: Insights From Three Generations of Women. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26297939 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675931 }} * {{medline-title |title=Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating Sirtuin. |date=08.07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26153625 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648391 }} * {{medline-title |title=[[SIRT3]] regulates progression and development of diseases of aging. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26138757 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558250 }} * {{medline-title |title=Sirtuin Functions in Female Fertility: Possible Role in Oxidative Stress and Aging. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26075037 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436464 }} * {{medline-title |title=Differential expression of sirtuins in the aging rat brain. |date=2015 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{{medline-title |title=Lisinopril Preserves Physical Resilience and Extends Life Span in a Genotype-Specific Manner in Drosophila melanogaster. |date=13.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31197356 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329186 }} * {{medline-title |title=Age-dependent differences in pulmonary host responses in ARDS: a prospective observational cohort study. |date=14.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31089908 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517452 }} * {{medline-title |title=Identifying the lifetime cognitive and socioeconomic antecedents of cognitive state: seven decades of follow-up in a British birth cohort study. |date=24.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31023749 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502022 }} * {{medline-title |title=Association between Adverse Childhood Experiences and Muscle Strength in Older Age. |date=2019 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{{medline-title |title=Newly manufactured Marukome MK-34-1 miso with angiotensin-converting enzyme inhibitory activity and its antihypertensive effects in genetic hypertensive rat models. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30631160 |full-text-url=https://sci-hub.do/10.1038/s41440-018-0197-z }} * {{medline-title |title=Impact of resilience on health in older adults: a cross-sectional analysis from the International Mobility in Aging Study (IMIAS). |date=28.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30498045 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278794 }} * {{medline-title |title=Age-related impairment in Addenbrooke's cognitive examination revised scores in patients with amyotrophic lateral sclerosis. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30379106 |full-text-url=https://sci-hub.do/10.1080/21678421.2018.1510009 }} * {{medline-title |title=The Edinburgh Cognitive and Behavioral ALS screen: relationship to age, 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|title=Age differences in arterial and venous extra-cerebral blood flow in healthy adults: contributions of vascular risk factors and genetic variants. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28120105 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548544 }} * {{medline-title |title=Participant and Public Involvement in Refining a Peer-Volunteering Active Aging Intervention: Project [[ACE]] (Active, Connected, Engaged). |date=19.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27927733 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946893 }} * {{medline-title |title=Inverse relationship between Alzheimer's disease and cancer, and other factors contributing to Alzheimer's disease: a systematic review. |date=22.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27875990 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120447 }} * {{medline-title |title=Chymase-dependent production of angiotensin II: an old enzyme in old hearts. 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|title=Angiotensin-Converting Enzyme Inhibitors and Parameters of Sarcopenia: Relation to Muscle Mass, Strength and Function: Data from the Berlin Aging Study-II (BASE-II). |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27665105 |full-text-url=https://sci-hub.do/10.1007/s40266-016-0396-8 }} * {{medline-title |title=Combined statin and angiotensin-converting enzyme ([[ACE]]) inhibitor treatment increases the lifespan of long-lived F1 male mice. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27590905 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266223 }} * {{medline-title |title=Establishing in-hospital geriatrics services in Africa: Insights from the University of Benin Teaching Hospital geriatrics project. |date=07-09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27549420 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402812 }} * {{medline-title |title=Age-Associated Changes in the Vascular Renin-Angiotensin System in Mice. 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|title=Part 4. Assessment of plasma markers and cardiovascular responses in rats after chronic exposure to new-technology diesel exhaust in the [[ACE]]S bioassay. |date=01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25842618 }} * {{medline-title |title=In vivo visualization of the antialbuminuric effects of the angiotensin-converting enzyme inhibitor enalapril. |date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25680709 |full-text-url=https://sci-hub.do/10.1124/jpet.114.222125 }} * {{medline-title |title=Embodiment effects and language comprehension in Alzheimer's disease. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25332184 |full-text-url=https://sci-hub.do/10.1111/cogs.12187 }} * {{medline-title |title=[[ACE]] polymorphism and use of [[ACE]] inhibitors: effects on memory performance. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24696269 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082601 }} * {{medline-title |title=[[ACE]] inhibitors, statins and thiazides: no association with change in grip strength among community dwelling older men and women from the Hertfordshire Cohort Study. |date=09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24522120 |full-text-url=https://sci-hub.do/10.1093/ageing/afu008 }} * {{medline-title |title=Genetic influence on exercise-induced changes in physical function among mobility-limited older adults. |date=01.03.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24423970 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949106 }} ==SOD2== * {{medline-title |title=Astaxanthin Counteracts Vascular Calcification In Vitro Through an Early Up-Regulation of [[SOD2]] Based on a Transcriptomic Approach. |date=12.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33198315 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698184 }} * {{medline-title |title=Alginate Oligosaccharide Prevents against D-galactose-mediated Cataract in C57BL/6J Mice via Regulating Oxidative Stress and Antioxidant System. |date=06.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33153341 |full-text-url=https://sci-hub.do/10.1080/02713683.2020.1842456 }} * {{medline-title |title=Protoflavones in melanoma therapy: Prooxidant and pro-senescence effect of protoapigenone and its synthetic alkyl derivative in A375 cells. |date=01.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32931795 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118419 }} * {{medline-title |title=Ginsenoside Rg1 protects against Sca-1 HSC/HPC cell aging by regulating the SIRT1-FOXO3 and SIRT3-[[SOD2]] signaling pathways in a γ-ray irradiation-induced aging mice model. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32765665 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388550 }} * {{medline-title |title=Almond Skin Extracts and Chlorogenic Acid Delay Chronological Aging and Enhanced Oxidative Stress Response in Yeast. |date=28.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32481725 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345664 }} * {{medline-title |title=Opposing p53 and mTOR/AKT promote an in vivo switch from apoptosis to senescence upon telomere shortening in zebrafish. |date=19.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32427102 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237213 }} * {{medline-title |title=Bioactive peptides derived from crimson snapper and in vivo anti-aging effects on fat diet-induced high fat Drosophila melanogaster. |date=29.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31844865 |full-text-url=https://sci-hub.do/10.1039/c9fo01414d }} * {{medline-title |title=Ellagic acid prolongs the lifespan of Drosophila melanogaster. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31786733 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031466 }} * {{medline-title |title=Chlorella vulgaris modulates the expression of senescence-associated genes in replicative senescence of human diploid fibroblasts. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31642042 |full-text-url=https://sci-hub.do/10.1007/s11033-019-05140-8 }} * {{medline-title |title=Age-Associated Changes in Antioxidants and Redox Proteins of Rat Heart. |date=30.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31647296 |full-text-url=https://sci-hub.do/10.33549/physiolres.934170 }} * {{medline-title |title=Impact of curcumin on replicative and chronological aging in the Saccharomyces cerevisiae yeast. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31659616 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942599 }} * {{medline-title |title=Age-Dependent Oxidative Stress Elevates Arginase 1 and Uncoupled Nitric Oxide Synthesis in Skeletal Muscle of Aged Mice. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31205583 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530149 }} * {{medline-title |title=Age-Related Oxidative Changes in Primary Porcine Fibroblasts Expressing Mutated Huntingtin. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31167196 |full-text-url=https://sci-hub.do/10.1159/000500091 }} * {{medline-title |title=Preventive effect of Lactobacillus plantarum KSFY02 isolated from naturally fermented yogurt from Xinjiang, China, on d-galactose-induced oxidative aging in mice. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31103296 |full-text-url=https://sci-hub.do/10.3168/jds.2018-16033 }} * {{medline-title |title=Protective effects of pyrroloquinoline quinine against oxidative stress-induced cellular senescence and inflammation in human renal tubular epithelial cells via Keap1/Nrf2 signaling pathway. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31035086 |full-text-url=https://sci-hub.do/10.1016/j.intimp.2019.04.040 }} * {{medline-title |title=Sex differences in the aging human heart: decreased sirtuins, pro-inflammatory shift and reduced anti-oxidative defense. |date=08.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30964749 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503880 }} * {{medline-title |title=NKT-like cells reveal higher than T lymphocytes expression of cellular protective proteins HSP70 and [[SOD2]] and comparably increased expression of [[SIRT1]] in the oldest seniors. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30633320 |full-text-url=https://sci-hub.do/10.5603/FHC.a2018.0025 }} * {{medline-title |title=Ku86 alleviates human umbilical vein endothelial cellular apoptosis and senescence induced by a low dose of ionizing radiation. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30616437 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381507 }} * {{medline-title |title=Putrescine delays postovulatory aging of mouse oocytes by upregulating [[PDK4]] expression and improving mitochondrial activity. |date=16.12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30554191 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326651 }} * {{medline-title |title=CD56bright cells respond to stimulation until very advanced age revealing increased expression of cellular protective proteins [[SIRT1]], HSP70 and [[SOD2]]. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30534181 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262966 }} * {{medline-title |title=Functional restoration of replicative senescent mesenchymal stem cells by the brown alga [i]Undaria pinnatifida[/i]. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30460058 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138307 }} * {{medline-title |title=[i]Lactobacillus plantarum[/i] CQPC11 Isolated from Sichuan Pickled Cabbages Antagonizes d-galactose-Induced Oxidation and Aging in Mice. |date=20.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463304 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278364 }} * {{medline-title |title=Superoxide dismutase activity is significantly lower in end-stage osteoarthritic cartilage than non-osteoarthritic cartilage. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30222787 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141073 }} * {{medline-title |title=Reactive oxygen species, aging and articular cartilage homeostasis. |date=20.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30176344 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342625 }} * {{medline-title |title=Cytokine modulation, oxidative stress and thymic dysfunctions: Role of age-related changes in the experimental Trypanosoma cruzi infection: Age-related thymic dysfunctions and Trypanosoma cruzi infection. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30130728 |full-text-url=https://sci-hub.do/10.1016/j.cyto.2018.08.004 }} * {{medline-title |title=Mitohormesis in Mice via Sustained Basal Activation of Mitochondrial and Antioxidant Signaling. |date=06.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30122556 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221994 }} * {{medline-title |title=Master athletes have higher miR-7, [[SIRT3]] and [[SOD2]] expression in skeletal muscle than age-matched sedentary controls. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30107294 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092475 }} * {{medline-title |title=Age-related changes in vascular responses to angiotensin-(1-7) in female mice. |date=07-09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30024321 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053867 }} * {{medline-title |title=Effect of β-D-Mannuronic Acid (M2000) on Oxidative Stress Enzymes' Gene Using Healthy Donor Peripheral Blood Mononuclear Cells for Evaluating the Anti-Aging Property. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29766814 |full-text-url=https://sci-hub.do/10.2174/1570163815666180515122834 }} * {{medline-title |title=The impact of preserved Klotho gene expression on antioxidative stress activity in healthy kidney. |date=01.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29693450 |full-text-url=https://sci-hub.do/10.1152/ajprenal.00486.2017 }} * {{medline-title |title=Age-related NMDA signaling alterations in [[SOD2]] deficient mice. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577983 |full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.03.019 }} * {{medline-title |title=Inhibition of oxidative stress in cholinergic projection neurons fully rescues aging-associated olfactory circuit degeneration in [i]Drosophila[/i]. |date=18.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29345616 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790380 }} * {{medline-title |title=Ultrafine particulate matter exposure impairs vasorelaxant response in superoxide dismutase 2-deficient murine aortic rings. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29279024 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136421 }} * {{medline-title |title=COCOA (Theobroma cacao) Polyphenol-Rich Extract Increases the Chronological Lifespan of Saccharomyces cerevisiae. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29240368 }} * {{medline-title |title=Yeast polyubiquitin gene UBI4 deficiency leads to early induction of apoptosis and shortened replicative lifespan. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29116578 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045546 }} * {{medline-title |title=Time-response characteristic and potential biomarker identification of heavy metal induced toxicity in zebrafish. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29111395 |full-text-url=https://sci-hub.do/10.1016/j.fsi.2017.10.047 }} * {{medline-title |title=Dietary supplementation with acetyl-l-carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807823 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.017 }} * {{medline-title |title=Aerobic exercise prevents rarefaction of pial collaterals and increased stroke severity that occur with aging. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28685617 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669350 }} * {{medline-title |title=Betaine promotes cell differentiation of human osteoblasts in primary culture. |date=07.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28592272 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463390 }} * {{medline-title |title=Vulnerability of white matter tracts and cognition to the [[SOD2]] polymorphism: A preliminary study of antioxidant defense genes in brain aging. |date=30.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28457881 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515475 }} * {{medline-title |title=Age-related reduction in the expression of FOXO transcription factors and correlations with intervertebral disc degeneration. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28430387 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650945 }} * {{medline-title |title=Ionizing radiation induces long-term senescence in endothelial cells through mitochondrial respiratory complex II dysfunction and superoxide generation. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28431961 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2017.04.019 }} * {{medline-title |title=An in vitro evaluation of anti-aging effect of guluronic acid (G2013) based on enzymatic oxidative stress gene expression using healthy individuals PBMCs. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28364598 |full-text-url=https://sci-hub.do/10.1016/j.biopha.2017.03.066 }} * {{medline-title |title=The In Vitro Influence of a Genetic Superoxide-Hydrogen Peroxide Imbalance on Immunosenescence. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28285577 |full-text-url=https://sci-hub.do/10.1089/rej.2016.1892 }} * {{medline-title |title=Anti-aging effects of M2000 (β-D-mannuronic acid) as a novel immunosuppressive drug on the enzymatic and non-enzymatic oxidative stress parameters in an experimental model. |date=01.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28207414 |full-text-url=https://sci-hub.do/10.1515/jbcpp-2016-0092 }} * {{medline-title |title=Expression of cellular protective proteins [[SIRT1]], HSP70 and [[SOD2]] correlates with age and is significantly higher in NK cells of the oldest seniors. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28127381 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259875 }} * {{medline-title |title=[[SIRT3]] mediates decrease of oxidative damage and prevention of ageing in porcine fetal fibroblasts. |date=15.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28131761 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2017.01.010 }} * {{medline-title |title=Loss of BOSS Causes Shortened Lifespan with Mitochondrial Dysfunction in Drosophila. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28045997 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207625 }} * {{medline-title |title=Altered S-nitrosylation of p53 is responsible for impaired antioxidant response in skeletal muscle during aging. |date=20.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28025407 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270679 }} * {{medline-title |title=Protective Effects of Hydrogen Sulfide in the Ageing Kidney. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27882191 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108860 }} * {{medline-title |title=Protective effects and mechanisms investigation of Kuntai capsule on the ovarian function of a novel model with accelerated aging ovaries. |date=04.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27845267 |full-text-url=https://sci-hub.do/10.1016/j.jep.2016.11.014 }} * {{medline-title |title=Response of [[BAX]], Bcl-2 Proteins, and [[SIRT1]]/[[PGC]]-1α mRNA Expression to 8-Week Treadmill Running in the Aging Rat Skeletal Muscle. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27526155 |full-text-url=https://sci-hub.do/10.1007/978-3-319-38810-6_38 }} * {{medline-title |title=Sirtuin 3 Deregulation Promotes Pulmonary Fibrosis. |date=01.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27522058 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964739 }} * {{medline-title |title=Blackberry, raspberry and black raspberry polyphenol extracts attenuate angiotensin II-induced senescence in vascular smooth muscle cells. |date=12.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27506987 |full-text-url=https://sci-hub.do/10.1039/c6fo00743k }} * {{medline-title |title=Purple sweet potato anthocyanin attenuates fat-induced mortality in Drosophila melanogaster. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27329928 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.06.006 }} * {{medline-title |title=Age-Associated Changes in the Vascular Renin-Angiotensin System in Mice. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27200147 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855022 }} * {{medline-title |title=Evidence that oxidative stress is higher in replacement gilts than in multiparous sows. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27079824 |full-text-url=https://sci-hub.do/10.1111/jpn.12462 }} * {{medline-title |title=Age-dependent changes of the antioxidant system in rat livers are accompanied by altered MAPK activation and a decline in motor signaling. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27004051 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800781 }} * {{medline-title |title=Aging Promotes Sirtuin 3-Dependent Cartilage Superoxide Dismutase 2 Acetylation and Osteoarthritis. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26866626 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331855 }} * {{medline-title |title=Targeting genes in insulin-associated signalling pathway, DNA damage, cell proliferation and cell differentiation pathways by tocotrienol-rich fraction in preventing cellular senescence of human diploid fibroblasts. |date=11-12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26794818 |full-text-url=https://sci-hub.do/10.7417/T.2015.1902 }} * {{medline-title |title=The Immp2l mutation causes age-dependent degeneration of cerebellar granule neurons prevented by antioxidant treatment. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26616244 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717271 }} * {{medline-title |title=Mitochondrial superoxide dismutase deficiency accelerates chronological aging in the fission yeast Schizosaccharomyces pombe. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26507459 |full-text-url=https://sci-hub.do/10.1002/cbin.10556 }} * {{medline-title |title=Oral treatment with herbal formula B307 alleviates cardiac failure in aging R6/2 mice with Huntington's disease via suppressing oxidative stress, inflammation, and apoptosis. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26229452 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516205 }} * {{medline-title |title=Cordyceps sinensis oral liquid prolongs the lifespan of the fruit fly, Drosophila melanogaster, by inhibiting oxidative stress. |date=10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26239097 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564082 }} * {{medline-title |title=Rejuvenation of MPTP-induced human neural precursor cell senescence by activating autophagy. |date=21.08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26159917 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.06.174 }} * {{medline-title |title=Effects of a recombinant complement component [[C3]]b functional fragment α2MR (α2-macroglobulin receptor) additive on the immune response of juvenile orange-spotted grouper (Epinephelus coioides) after the exposure to cold shock challenge. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25917969 |full-text-url=https://sci-hub.do/10.1016/j.fsi.2015.04.019 }} * {{medline-title |title=A correlation of reactive oxygen species accumulation by depletion of superoxide dismutases with age-dependent impairment in the nervous system and muscles of Drosophila adults. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25801590 |full-text-url=https://sci-hub.do/10.1007/s10522-015-9570-3 }} * {{medline-title |title=Ameliorative effect of black rice anthocyanin on senescent mice induced by D-galactose. |date=11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25190075 |full-text-url=https://sci-hub.do/10.1039/c4fo00391h }} * {{medline-title |title=Increased production of mitochondrial reactive oxygen species and reduced adult life span in an insecticide-resistant strain of Anopheles gambiae. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24555527 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008687 }} * {{medline-title |title=Age-related decrease in the mitochondrial sirtuin deacetylase Sirt3 expression associated with ROS accumulation in the auditory cortex of the mimetic aging rat model. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24505357 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913718 }} * {{medline-title |title=Lifelong training preserves some redox-regulated adaptive responses after an acute exercise stimulus in aged human skeletal muscle. |date=05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24525000 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2014.02.004 }} * {{medline-title |title=Absence of superoxide dismutase activity causes nuclear DNA fragmentation during the aging process. |date=07.02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462872 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2014.01.056 }} * {{medline-title |title=Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway. |date=04.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462499 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050201 }} ==TERT== * {{medline-title |title=Telomeres and telomerase in risk assessment of cardiovascular diseases. |date=15.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33171154 |full-text-url=https://sci-hub.do/10.1016/j.yexcr.2020.112361 }} * {{medline-title |title=A 4-Base-Pair Core-Enclosing Helix in Telomerase RNA Is Essential for Activity and for Binding to the Telomerase Reverse Transcriptase Catalytic Protein Subunit. |date=20.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33046533 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685517 }} * {{medline-title |title=Angiotensin inhibition and cellular senescence in the developing rat kidney. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33010296 |full-text-url=https://sci-hub.do/10.1016/j.yexmp.2020.104551 }} * {{medline-title |title=Decreased expression of [[TERT]] and telomeric proteins as human ovaries age may cause telomere shortening. |date=27.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32856217 |full-text-url=https://sci-hub.do/10.1007/s10815-020-01932-1 }} * {{medline-title |title=The secrets of telomerase: Retrospective analysis and future prospects. |date=15.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32698073 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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32039527 |full-text-url=https://sci-hub.do/10.1002/cbin.11319 }} * {{medline-title |title=Aging and biomarkers: Transcriptional levels evaluation of Osteopontin/miRNA-181a axis in hepatic tissue of rats in different age ranges. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32061643 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110879 }} * {{medline-title |title=Resveratrol inhibits adipocyte differentiation and cellular senescence of human bone marrow stromal stem cells. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31978617 |full-text-url=https://sci-hub.do/10.1016/j.bone.2020.115252 }} * {{medline-title |title=Characterization of human telomerase reverse transcriptase immortalized anterior cruciate ligament cell lines. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31948601 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962762 }} * {{medline-title |title=Mitochondria, Telomeres and 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{{medline-title |title=Role of Telomerase in the Cardiovascular System. |date=17.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27322328 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929428 }} * {{medline-title |title=Stimulation of cell proliferation by glutathione monoethyl ester in aged bone marrow stromal cells is associated with the assistance of [[TERT]] gene expression and telomerase activity. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27251157 |full-text-url=https://sci-hub.do/10.1007/s11626-016-0021-5 }} * {{medline-title |title=Generation of mice with longer and better preserved telomeres in the absence of genetic manipulations. |date=02.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27252083 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895768 }} * {{medline-title |title=Neuroprotective effects of the catalytic subunit of telomerase: A potential therapeutic target in the central nervous system. |date=07.2016 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|title=Resident health-related quality of life in Swiss nursing homes. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25801468 |full-text-url=https://sci-hub.do/10.1016/j.eurpsy.2014.10.001 }} * {{medline-title |title=Glyphosate resistance in Echinochloa colona: phenotypic characterisation and quantification of selection intensity. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25779335 |full-text-url=https://sci-hub.do/10.1002/ps.4005 }} * {{medline-title |title=Comparison of life history and genetic properties of cowpea bruchid strains and their response to hypoxia. |date=04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25733404 |full-text-url=https://sci-hub.do/10.1016/j.jinsphys.2015.02.008 }} * {{medline-title |title=Long-term test-retest reliability of delayed reward discounting in adolescents. |date=02.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25447508 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306354 }} * {{medline-title 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cultivars. |date=01.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24381436 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3550679 }} * {{medline-title |title=Neonatal alcohol impairs the context preexposure facilitation effect in juvenile rats: dose-response and post-training consolidation effects. |date=02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24387902 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077280 }} ==SIRT6== * {{medline-title |title=Association between [[SIRT6]] Methylation and Human Longevity in a Chinese Population. |date=25.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33238266 |full-text-url=https://sci-hub.do/10.1159/000508832 }} * {{medline-title |title=The [[SIRT6]] activator MDL-800 improves genomic stability and pluripotency of old murine-derived iPS cells. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33089974 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431819 }} * {{medline-title |title=Sirtuins as Possible Predictors of Aging and Alzheimer's Disease Development: Verification in the Hippocampus and Saliva. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33098511 |full-text-url=https://sci-hub.do/10.1007/s10517-020-04986-4 }} * {{medline-title |title=Age-related epigenetic drift deregulates [i][[SIRT6]][/i] expression and affects its downstream genes in human peripheral blood mononuclear cells. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32573339 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678931 }} * {{medline-title |title=Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators. |date=07.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32518153 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415977 }} * {{medline-title |title=Age-dependent role of [[SIRT6]] in jawbone via regulating senescence and autophagy of bone marrow stromal cells. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32002721 |full-text-url=https://sci-hub.do/10.1007/s10735-020-09857-w }} * {{medline-title |title=Mechanism of activation for the sirtuin 6 protein deacylase. |date=31.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31822559 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996886 }} * {{medline-title |title=Proteomics of Long-Lived Mammals. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31737995 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117992 }} * {{medline-title |title=Sirtuins and [[SIRT6]] in Carcinogenesis and in Diet. |date=07.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31591350 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801518 }} * {{medline-title |title=[[SIRT6]]-mediated transcriptional suppression of MALAT1 is a key mechanism for endothelial to mesenchymal transition. |date=15.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31399301 |full-text-url=https://sci-hub.do/10.1016/j.ijcard.2019.07.082 }} * {{medline-title |title=[[SIRT6]] Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. |date=18.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31002797 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499390 }} * {{medline-title |title=[[SIRT6]] participates in the quality control of aged oocytes via modulating telomere function. |date=29.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30926765 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503879 }} * {{medline-title |title=LINE1 Derepression in Aged Wild-Type and [[SIRT6]]-Deficient Mice Drives Inflammation. |date=02.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30853213 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449196 }} * {{medline-title |title=Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism. |date=23.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30673631 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366955 }} * {{medline-title |title=Diesel exhaust exposure intensifies inflammatory and structural changes associated with lung aging in mice. |date=15.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30530184 |full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.11.139 }} * {{medline-title |title=Phosphodiesterase 4 inhibitor activates AMPK-[[SIRT6]] pathway to prevent aging-related adipose deposition induced by metabolic disorder. |date=18.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30227388 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188481 }} * {{medline-title |title=MiR-125b attenuates human hepatocellular carcinoma malignancy through targeting [[SIRT6]]. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30034937 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048406 }} * {{medline-title |title=Role of accelerated aging in limb muscle wasting of patients with COPD. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29970961 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022820 }} * {{medline-title |title=A Review of the Recent Advances Made with [[SIRT6]] and its Implications on Aging Related Processes, Major Human Diseases, and Possible Therapeutic Targets. |date=29.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966233 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164879 }} * {{medline-title |title=Application of multivariate longitudinal models in [[SIRT6]], FBS, and BMI analysis of the elderly. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29901417 |full-text-url=https://sci-hub.do/10.1080/13685538.2018.1477933 }} * {{medline-title |title=Sirtuins in Renal Health and Disease. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29712732 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050939 }} * {{medline-title |title=Boosting [[ATM]] activity alleviates aging and extends lifespan in a mouse model of progeria. |date=02.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29717979 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957528 }} * {{medline-title |title=High expression of CPT1b in skeletal muscle in metabolically healthy older subjects. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29657112 |full-text-url=https://sci-hub.do/10.1016/j.diabet.2018.01.018 }} * {{medline-title |title=Haploinsufficiency of [i]Trp53[/i] dramatically extends the lifespan of Sirt6-deficient mice. |date=23.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29474172 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825207 }} * {{medline-title |title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 }} * {{medline-title |title=Stem Cells and Progenitors in Human Peripheral Blood Get Activated by Extremely Active Resveratrol (XAR™). |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177909 |full-text-url=https://sci-hub.do/10.1007/s12015-017-9784-7 }} * {{medline-title |title=Aging as an Epigenetic Phenomenon. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081695 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635645 }} * {{medline-title |title=Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28767699 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540417 }} * {{medline-title |title=[[SIRT1]] and [[SIRT6]] Signaling Pathways in Cardiovascular Disease Protection. |date=10.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28661724 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824538 }} * {{medline-title |title=Ursolic Acid Mediates Hepatic Protection through Enhancing of anti-aging Biomarkers. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28558631 |full-text-url=https://sci-hub.do/10.2174/1874609810666170531103140 }} * {{medline-title |title=Characterization of physiological defects in adult [[SIRT6]]-/- mice. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28448551 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407791 }} * {{medline-title |title=Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts. |date=01.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28385812 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495944 }} * {{medline-title |title=[[SIRT6]] polymorphism rs117385980 is associated with longevity and healthy aging in Finnish men. |date=11.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28399814 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387321 }} * {{medline-title |title=Neuroprotective Functions for the Histone Deacetylase [[SIRT6]]. |date=28.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28355558 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389893 }} * {{medline-title |title=Cosmeceutical product consisting of biomimetic peptides: antiaging effects in vivo and in vitro. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28123310 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234555 }} * {{medline-title |title=Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27882448 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357501 }} * {{medline-title |title=[[SIRT6]]: Novel Mechanisms and Links to Aging and Disease. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27836583 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326594 }} * {{medline-title |title=Multiple pathways of [[SIRT6]] at the crossroads in the control of longevity, cancer, and cardiovascular diseases. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27829173 |full-text-url=https://sci-hub.do/10.1016/j.arr.2016.10.008 }} * {{medline-title |title=[[SIRT6]] delays cellular senescence by promoting p27Kip1 ubiquitin-proteasome degradation. |date=16.09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27794562 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115890 }} * {{medline-title |title=The protein-interaction network with functional roles in tumorigenesis, neurodegeneration, and aging. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27699588 |full-text-url=https://sci-hub.do/10.1007/s11010-016-2836-5 }} * {{medline-title |title=[[SIRT6]] Overexpression Improves Various Aspects of Mouse Healthspan. |date=01.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27519885 |full-text-url=https://sci-hub.do/10.1093/gerona/glw152 }} * {{medline-title |title=Slowing ageing by design: the rise of NAD and sirtuin-activating compounds. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27552971 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107309 }} * {{medline-title |title=Ursolic acid regulates aging process through enhancing of metabolic sensor proteins level. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27470332 |full-text-url=https://sci-hub.do/10.1016/j.biopha.2016.04.047 }} * {{medline-title |title=Ergothioneine oxidation in the protection against high-glucose induced endothelial senescence: Involvement of [[SIRT1]] and [[SIRT6]]. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27101740 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2016.04.013 }} * {{medline-title |title=Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins. |date=15.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27038700 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.03.015 }} * {{medline-title |title=AMPK/Snf1 signaling regulates histone acetylation: Impact on gene expression and epigenetic functions. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27010499 |full-text-url=https://sci-hub.do/10.1016/j.cellsig.2016.03.009 }} * {{medline-title |title=Calorie restriction-induced [[SIRT6]] activation delays aging by suppressing NF-κB signaling. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26940461 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889297 }} * {{medline-title |title=Sirtuins, Cell Senescence, and Vascular Aging. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26948035 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848124 }} * {{medline-title |title=Lack of association between polymorphisms in the [[SIRT6]] gene and longevity in a Chinese population. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26802595 |full-text-url=https://sci-hub.do/10.1016/j.mcp.2016.01.005 }} * {{medline-title |title=[[SIRT6]], oxidative stress, and aging. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26780861 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746614 }} * {{medline-title |title=Sirt6 regulates dendritic cell differentiation, maturation, and function. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26761436 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761712 }} * {{medline-title |title=The complex role of [[SIRT6]] in carcinogenesis. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26717993 |full-text-url=https://sci-hub.do/10.1093/carcin/bgv167 }} * {{medline-title |title=The expression levels of the sirtuins in patients with BCC. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26631040 |full-text-url=https://sci-hub.do/10.1007/s13277-015-4522-8 }} * {{medline-title |title=Localization of sirtuins ([[SIRT1]]-7) in the aged mouse inner ear. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26472659 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|date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25683165 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452156 }} * {{medline-title |title=[[SIRT6]] represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age. |date=23.09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25247314 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185372 }} * {{medline-title |title=Changes in human sirtuin 6 gene promoter methylation during aging. |date=07.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24944811 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051482 }} * {{medline-title |title=Sirtuins: guardians of mammalian healthspan. |date=07.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24877878 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077918 }} * {{medline-title |title=Comparative interactomes of [[SIRT6]] and [[SIRT7]]: Implication of functional links to aging. |date=07.2014 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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33023448 |full-text-url=https://sci-hub.do/10.2174/1567205017666201006162538 }} * {{medline-title |title=Human ESC-sEVs alleviate age-related bone loss by rejuvenating senescent bone marrow-derived mesenchymal stem cells. |date=10.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32944188 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480439 }} * {{medline-title |title=The precursor of PI(3,4,5)P alleviates aging by activating daf-18(Pten) and independent of daf-16. |date=08.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32901024 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479145 }} * {{medline-title |title=Quercetin alleviates kidney fibrosis by reducing renal tubular epithelial cell senescence through the SIRT1/PINK1/mitophagy axis. |date=15.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32702447 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118116 }} * {{medline-title |title=Downregulation of [[PTEN]] mediates bleomycin-induced premature senescence in lung cancer cells by suppressing autophagy. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32436415 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287201 }} * {{medline-title |title=miR-155 inhibits mitophagy through suppression of BAG5, a partner protein of PINK1. |date=12.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31948758 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.01.022 }} * {{medline-title |title=Environmental Exposures and Asthma Development: Autophagy, Mitophagy, and Cellular Senescence. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31849968 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896909 }} * {{medline-title |title=[[PTEN]] loss regulates alveolar epithelial cell senescence in pulmonary fibrosis depending on Akt activation. |date=17.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31527305 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781970 }} * {{medline-title |title=Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298565 |full-text-url=https://sci-hub.do/10.1089/cell.2019.0010 }} * {{medline-title |title=Role of IL-37 in Cardiovascular Disease Inflammation. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292092 |full-text-url=https://sci-hub.do/10.1016/j.cjca.2019.04.007 }} * {{medline-title |title=Abrogation of B-Raf induced senescence by FoxM1 expression. |date=27.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31270027 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.06.144 }} * {{medline-title |title=Oncogenic mutations in histologically normal endometrium: the new normal? |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187483 |full-text-url=https://sci-hub.do/10.1002/path.5314 }} * {{medline-title |title=Double knockout of Akt2 and AMPK predisposes cardiac aging without affecting lifespan: Role of autophagy and mitophagy. |date=01.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31109453 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530587 }} * {{medline-title |title=Single Cell Profiling Reveals [[PTEN]] Overexpression in Influenza-Specific B cells in Aging HIV-infected individuals on Anti-retroviral Therapy. |date=21.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30792481 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385500 }} * {{medline-title |title=[[KIN]]-4/MAST kinase promotes [[PTEN]]-mediated longevity of Caenorhabditis elegans via binding through a PDZ domain. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30773781 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516182 }} * {{medline-title |title=Loss of [[PTEN]] induces lung fibrosis via alveolar epithelial cell senescence depending on NF-κB activation. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30548445 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351835 }} * {{medline-title |title=Increased susceptibility of aging gastric mucosa to injury and delayed healing: Clinical implications. |date=14.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30479459 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235800 }} * {{medline-title |title=[[PRKN]]-regulated mitophagy and cellular senescence during COPD pathogenesis. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30290714 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351145 }} * {{medline-title |title=[[MCL1]] gene silencing promotes senescence and apoptosis of glioma cells via inhibition of the PI3K/Akt signaling pathway. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30296359 |full-text-url=https://sci-hub.do/10.1002/iub.1944 }} * {{medline-title |title=Grape skin extract improves muscle function and extends lifespan of a Drosophila model of Parkinson's disease through activation of mitophagy. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30248358 |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.09.014 }} * {{medline-title |title=Berberine ameliorates renal injury in a rat model of D-galactose-induced aging through a [[PTEN]]/Akt-dependent mechanism. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30145915 |full-text-url=https://sci-hub.do/10.1080/13813455.2018.1499117 }} * {{medline-title |title=Neuronal Preconditioning Requires the Mitophagic Activity of C-terminus of HSC70-Interacting Protein. |date=01.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29934347 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070662 }} * {{medline-title |title=Endothelial replicative senescence delayed by the inhibition of [[MTOR]]C1 signaling involves MicroRNA-107. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29857052 |full-text-url=https://sci-hub.do/10.1016/j.biocel.2018.05.016 }} * {{medline-title |title=Stanozolol administration combined with exercise leads to decreased telomerase activity possibly associated with liver aging. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29717770 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979936 }} * {{medline-title |title=Ablation of toll-like receptor 4 attenuates aging-induced myocardial remodeling and contractile dysfunction through NCoRI-[[HDAC1]]-mediated regulation of autophagy. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29660306 |full-text-url=https://sci-hub.do/10.1016/j.yjmcc.2018.04.009 }} * {{medline-title |title=Changes in expression of special AT-rich sequence binding protein 1 and phosphatase and tensin homologue in kidneys of diabetic rats during ageing. |date=01.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29506055 |full-text-url=https://sci-hub.do/10.1093/ndt/gfy003 }} * {{medline-title |title=Beyond regulation of pol III: Role of [[MAF1]] in growth, metabolism, aging and cancer. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29407795 |full-text-url=https://sci-hub.do/10.1016/j.bbagrm.2018.01.019 }} * {{medline-title |title=Neuronal [[PTEN]] deletion in adult cortical neurons triggers progressive growth of cell bodies, dendrites, and axons. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29337147 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864555 }} * {{medline-title |title=Genetic Ablation of [i]Rbm38[/i] Promotes Lymphomagenesis in the Context of Mutant p53 by Downregulating [[PTEN]]. |date=15.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29330147 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340497 }} * {{medline-title |title=miR-21 suppression prevents cardiac alterations induced by d-galactose and doxorubicin. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29329959 |full-text-url=https://sci-hub.do/10.1016/j.yjmcc.2018.01.007 }} * {{medline-title |title=MicroRNA-21 promotes glioma cell proliferation and inhibits senescence and apoptosis by targeting [[SPRY1]] via the [[PTEN]]/PI3K/AKT signaling pathway. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29316313 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489721 }} * {{medline-title |title=Global mapping of transcription factor motifs in human aging. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29293662 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749797 }} * {{medline-title |title=CRISPR-Cas9 Mediated Telomere Removal Leads to Mitochondrial Stress and Protein Aggregation. |date=03.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28972555 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666775 }} * {{medline-title |title=Akt2 ablation prolongs life span and improves myocardial 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signaling in the mouse ventral prostate. |date=09.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28439009 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441728 }} * {{medline-title |title=A Multigene Test Could Cost-Effectively Help Extend Life Expectancy for Women at Risk of Hereditary Breast Cancer. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28407996 |full-text-url=https://sci-hub.do/10.1016/j.jval.2017.01.006 }} * {{medline-title |title=Disruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28317237 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418188 }} * {{medline-title |title=Disrupting the key circadian regulator [[CLOCK]] leads to age-dependent cardiovascular disease. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28223222 |full-text-url=https://sci-hub.do/10.1016/j.yjmcc.2017.01.008 }} * {{medline-title |title=Overactive mTOR signaling leads to endometrial hyperplasia in aged women and mice. |date=31.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27980219 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352319 }} * {{medline-title |title=Identification of [i]Salvia haenkei[/i] as gerosuppressant agent by using an integrated senescence-screening assay. |date=01.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27922821 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270665 }} * {{medline-title |title=Altered mitochondrial quality control signaling in muscle of old gastric cancer patients with cachexia. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27847330 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.10.003 }} * {{medline-title |title=Dietary rapamycin supplementation reverses age-related vascular dysfunction and oxidative stress, while modulating nutrient-sensing, cell cycle, and senescence pathways. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27660040 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242306 }} * {{medline-title |title=GBM-associated mutations and altered protein expression are more common in young patients. |date=25.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27579614 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342491 }} * {{medline-title |title=C. elegans Methods to Study [[PTEN]]. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27033082 |full-text-url=https://sci-hub.do/10.1007/978-1-4939-3299-3_17 }} * {{medline-title |title=Inorganic Phosphate Activates the AKT/mTORC1 Pathway and Shortens the Life Span of an α‑Klotho-Deficient Model. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26872488 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004643 }} * {{medline-title |title=A [[PTEN]] inhibitor displays preclinical activity against hepatocarcinoma cells. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26794644 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056616 }} * {{medline-title |title=Effect of [[TIMP1]] transfection on [[PTEN]] expression in human kidney proximal tubular cells. |date=21.12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26782378 |full-text-url=https://sci-hub.do/10.4238/2015.December.21.6 }} * {{medline-title |title=Ribosomal L1 domain and lysine-rich region are essential for CSIG/ [[RSL1D1]] to regulate proliferation and senescence. |date=15.01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26686419 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.12.004 }} * {{medline-title |title=[[PTEN]] is required to maintain luminal epithelial homeostasis and integrity in the adult mammary gland. |date=01.01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26526198 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688181 }} * {{medline-title |title=Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26168237 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500567 }} * {{medline-title |title=Effects of age and unaccustomed resistance exercise on mitochondrial transcript and protein abundance in skeletal muscle of men. |date=15.04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25695287 |full-text-url=https://sci-hub.do/10.1152/ajpregu.00005.2014 }} * {{medline-title |title=[[PTEN]]/Akt-p27(kip1) Signaling Promote the BM-MSCs Senescence and Apoptosis in SLE Patients. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25649549 |full-text-url=https://sci-hub.do/10.1002/jcb.25112 }} * {{medline-title |title=Loss of JUNB/AP-1 promotes invasive prostate cancer. |date=04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25526087 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356344 }} * {{medline-title |title=Superoxide anion radicals induce IGF-1 resistance through concomitant activation of PTP1B and [[PTEN]]. |date=01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25520316 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309668 }} * {{medline-title |title=Mammalian target of rapamycin's distinct roles and effectiveness in promoting compensatory axonal sprouting in the injured CNS. |date=12.11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25392502 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228137 }} * {{medline-title |title=A functional genomic screen for evolutionarily conserved genes required for lifespan and immunity in germline-deficient C. elegans. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25093668 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122342 }} * {{medline-title |title=Phenotypic characterization of recessive gene knockout rat models of Parkinson's disease. |date=10.2014 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{{medline-title |title=[Reinnervation of central visual areas and recovery of visual functions following optic nerve regeneration in adult mice]. |date=03.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24607951 }} * {{medline-title |title=High-resolution profiling of stationary-phase survival reveals yeast longevity factors and their genetic interactions. |date=02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24586198 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937222 }} * {{medline-title |title=Insulin/IGF1 signaling inhibits age-dependent axon regeneration. |date=05.02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24440228 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924874 }} ==H2AX== * {{medline-title |title=Evaluation of Gamma[[H2AX]] in Buccal Cells as a Molecular Biomarker of DNA Damage in Alzheimer's Disease in the AIBL Study of Ageing. |date=06.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32781776 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Protocol for a prospective observational study. |date=25.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31772111 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887091 }} * {{medline-title |title=Slower rates of accumulation of DNA damage in leukocytes correlate with longer lifespans across several species of birds and mammals. |date=15.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31730540 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874430 }} * {{medline-title |title=Phosphoproteomic analysis reveals plant DNA damage signalling pathways with a functional role for histone [[H2AX]] phosphorylation in plant growth under genotoxic stress. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31410901 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900162 }} * {{medline-title |title=Rag1 immunodeficiency-induced early aging and senescence in zebrafish are dependent on chronic inflammation and oxidative stress. |date=10.2019 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|full-text-url=https://sci-hub.do/10.1080/09168451.2019.1585744 }} * {{medline-title |title=[[S100A13]] promotes senescence-associated secretory phenotype and cellular senescence via modulation of non-classical secretion of IL-1α. |date=23.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30670674 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366962 }} * {{medline-title |title=Clostridium difficile toxin B induces senescence in enteric glial cells: A potential new mechanism of Clostridium difficile pathogenesis. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30296499 |full-text-url=https://sci-hub.do/10.1016/j.bbamcr.2018.10.007 }} * {{medline-title |title=Varenicline reduces DNA damage, tau mislocalization and post surgical cognitive impairment in aged mice. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30273594 |full-text-url=https://sci-hub.do/10.1016/j.neuropharm.2018.09.044 }} * {{medline-title |title=The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30235328 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147527 }} * {{medline-title |title=Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187775 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180720 }} * {{medline-title |title=Acetylation of PGC1α by Histone Deacetylase 1 Downregulation Is Implicated in Radiation-Induced Senescence of Brain Endothelial Cells. |date=16.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30016403 |full-text-url=https://sci-hub.do/10.1093/gerona/gly167 }} * {{medline-title |title=Role of accelerated aging in limb muscle wasting of patients with COPD. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29970961 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022820 }} * {{medline-title |title=[Protective effect of Wuzi Yanzong recipe on testicular DNA damage and apoptosis in natural ageing rats]. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29751716 |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180115.005 }} * {{medline-title |title=Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions. |date=04.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29249653 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756112 }} * {{medline-title |title=Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice. |date=15.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29141658 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688691 }} * {{medline-title |title=Therapeutic doses of doxorubicin induce premature senescence of human mesenchymal stem cells derived from menstrual blood, bone marrow and adipose tissue. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29022209 |full-text-url=https://sci-hub.do/10.1007/s12185-017-2346-6 }} * {{medline-title |title=Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice. |date=07.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807355 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.08.035 }} * {{medline-title |title=The Cytolethal Distending Toxin Subunit CdtB of [i]Helicobacter hepaticus[/i] Promotes Senescence and Endoreplication in Xenograft Mouse Models of Hepatic and Intestinal Cell Lines. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28713773 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491915 }} * {{medline-title |title=Increased level of DNA damage in some organs of obese Zucker rats by γ-[[H2AX]] analysis. |date=08.2017 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senescence-associated cell death and necrosis in glioma cell lines: The proteasome inhibitor, bortezomib, potentiates axitinib-induced cytotoxicity in a p21(Waf/Cip1) dependent manner. |date=10.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27926485 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356889 }} * {{medline-title |title=Detection of Dysfunctional Telomeres in Oncogene-Induced Senescence. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27812868 |full-text-url=https://sci-hub.do/10.1007/978-1-4939-6670-7_6 }} * {{medline-title |title=Transgenic expression of cyclooxygenase-2 (COX2) causes premature aging phenotypes in mice. |date=07.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27750221 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115895 }} * {{medline-title |title=Overexpression of catalase in mice reduces age-related oxidative stress and maintains sperm production. |date=11.2016 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|title=Growth arrest of lung carcinoma cells (A549) by polyacrylate-anchored peroxovanadate by activating Rac1-NADPH oxidase signalling axis. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27435854 |full-text-url=https://sci-hub.do/10.1007/s11010-016-2761-7 }} * {{medline-title |title=p53-Dependent DNA damage response sensitive to editing-defective tRNA synthetase in zebrafish. |date=26.07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27402763 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968768 }} * {{medline-title |title=Mesenchymal stromal cells having inactivated [[RB1]] survive following low irradiation and accumulate damaged DNA: Hints for side effects following radiotherapy. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27124644 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323029 }} * {{medline-title |title=The impact of autophagy on cell death modalities in CRL-5876 lung adenocarcinoma cells after their exposure to γ-rays 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mitotic catastrophe, and increased NK cell recognition in human renal carcinoma cells. |date=03.11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26474283 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742174 }} * {{medline-title |title=Comparative proteomic analysis of primordial follicles from ovaries of immature and aged rats. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26391928 |full-text-url=https://sci-hub.do/10.3109/19396368.2015.1077903 }} * {{medline-title |title=Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities. |date=18.08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26240351 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547227 }} * {{medline-title |title=Impairing the radioresistance of cancer cells by hydrogenated nanodiamonds. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26010122 |full-text-url=https://sci-hub.do/10.1016/j.biomaterials.2015.05.034 }} * {{medline-title |title=Age-related change in γ[[H2AX]] of Drosophila muscle: its significance as a marker for muscle damage and longevity. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25860864 |full-text-url=https://sci-hub.do/10.1007/s10522-015-9573-0 }} * {{medline-title |title=Depletion of [[SI]]RT6 causes cellular senescence, DNA damage, and telomere dysfunction in human chondrocytes. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25819580 |full-text-url=https://sci-hub.do/10.1016/j.joca.2015.03.024 }} * {{medline-title |title=Long-term arsenite exposure induces premature senescence in B cell lymphoma A20 cells. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25787150 |full-text-url=https://sci-hub.do/10.1007/s00204-015-1500-2 }} * {{medline-title |title=Changes in the expression of DNA double strand break repair genes in primordial follicles from immature and aged rats. |date=03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25599822 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|title=[Correlation between DNA damage and EB virus infection in nasopharyngeal carcinoma]. |date=02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24491061 }} * {{medline-title |title=Phosphorylation of histone [[H2AX]] in the mouse brain from development to senescence. |date=21.01.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24451138 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907886 }} ==NLRP3== * {{medline-title |title=Innate and Adaptive Immunity in Aging and Longevity: The Foundation of Resilience. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33269094 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673842 }} * {{medline-title |title=TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity. |date=27.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33113366 |full-text-url=https://sci-hub.do/10.1016/j.celrep.2020.108326 }} * {{medline-title |title=Repeated propofol exposure-induced neuronal damage and cognitive impairment in aged rats by activation of NF-κB pathway and [[NLRP3]] inflammasome. |date=01.01.2021 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33115643 |full-text-url=https://sci-hub.do/10.1016/j.neulet.2020.135461 }} * {{medline-title |title=A Small Molecule Stabilizer of the MYC G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma. |date=13.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066043 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650714 }} * {{medline-title |title=Interleukin-1β Drives Cellular Senescence of Rat Astrocytes Induced by Oligomerized Amyloid β Peptide and Oxidative Stress. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013631 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493674 }} * {{medline-title |title=Mechanisms of [[NLRP3]] priming in inflammaging and age related diseases. |date=10.2020 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Inflammasome Reduces Age-Related Experimental Alveolar Bone Loss. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32531176 |full-text-url=https://sci-hub.do/10.1177/0022034520933533 }} * {{medline-title |title=Korean Red Ginseng Suppresses the Expression of Oxidative Stress Response and [[NLRP3]] Inflammasome Genes in Aged C57BL/6 Mouse Ovaries. |date=22.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32331214 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231237 }} * {{medline-title |title=Cepharanthine promotes the effect of dexmedetomidine on the deposition of β-amyloid in the old age of the senile dementia rat model by regulating inflammasome expression. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32337948 |full-text-url=https://sci-hub.do/10.5114/fn.2019.89855 }} * {{medline-title |title=Ginsenoside Rg1 ameliorates glomerular fibrosis during kidney aging by inhibiting NOX4 and [[NLRP3]] inflammasome activation in SAMP8 mice. |date=27.02.2020 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mice. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31625260 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974709 }} * {{medline-title |title=Reduced NRF2 expression suppresses endothelial progenitor cell function and induces senescence during aging. |date=08.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31494646 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756903 }} * {{medline-title |title=Effect of Aging on Taurine Transporter (TauT) Expression in the Mouse Brain Cortex. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31468381 |full-text-url=https://sci-hub.do/10.1007/978-981-13-8023-5_1 }} * {{medline-title |title=Tamoxifen-induced, intestinal-specific deletion of [i]Slc5a6[/i] in adult mice leads to spontaneous inflammation: involvement of NF-κB, [[NLRP3]], and gut microbiota. |date=01.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31369292 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842991 }} * {{medline-title |title=Systemic inflammation impairs microglial Aβ clearance through [[NLRP3]] inflammasome. |date=02.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31359456 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717897 }} * {{medline-title |title=Aging in the Syrian hamster testis: Inflammatory-oxidative status and the impact of photoperiod. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31276778 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110649 }} * {{medline-title |title=[Improved effects of saponins from Panax japonicus on decline of cognitive function in natural aging rats via [[NLRP3]] inflammasome pathway]. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30989956 |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180921.001 }} * {{medline-title |title=Lack of [[NLRP3]] Inflammasome Activation Reduces Age-Dependent Sarcopenia and Mitochondrial Dysfunction, Favoring the Prophylactic Effect of Melatonin. |date=04.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30869745 |full-text-url=https://sci-hub.do/10.1093/gerona/glz079 }} * {{medline-title |title=Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks. |date=11.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862067 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429360 }} * {{medline-title |title=[[NLRP3]]/IL1β inflammasome associated with the aging bladder triggers bladder dysfunction in female rats. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30720125 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423574 }} * {{medline-title |title=Mitochondrial Stress-Initiated Aberrant Activation of the [[NLRP3]] Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging. |date=22.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30673616 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371804 }} * {{medline-title |title=Purple sweet potato color attenuated [[NLRP3]] inflammasome by inducing autophagy to delay endothelial senescence. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585631 |full-text-url=https://sci-hub.do/10.1002/jcp.28003 }} * {{medline-title |title=Inhibiting the [[NLRP3]] Inflammasome With MCC950 Ameliorates Isoflurane-Induced Pyroptosis and Cognitive Impairment in Aged Mice. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30524241 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262296 }} * {{medline-title |title=Klotho controls the brain-immune system interface in the choroid plexus. |date=27.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30413620 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275534 }} * {{medline-title |title=[[NLRP3]] inflammasome activation in inflammaging. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30268598 |full-text-url=https://sci-hub.do/10.1016/j.smim.2018.09.001 }} * {{medline-title |title=Melatonin and inflammation-Story of a double-edged blade. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30242884 |full-text-url=https://sci-hub.do/10.1111/jpi.12525 }} * {{medline-title |title=A response to readers' comments. |date=14.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217141 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138902 }} * {{medline-title |title=[[NLRP3]] inflammasome-dependent pyroptosis is proposed to be involved in the mechanism of age-dependent isoflurane-induced cognitive impairment. |date=14.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217191 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138927 }} * {{medline-title |title=Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30065258 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146930 }} * {{medline-title |title=Pro- and Anti-inflammatory Effects of High Cholesterol Diet on Aged Brain. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29896426 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988593 }} * {{medline-title |title=Critical role of [[NLRP3]]-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment. |date=17.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29665808 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904978 }} * {{medline-title |title=Decreased [[NLRP3]] inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203400 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869149 }} * {{medline-title |title=AMP-Activated Protein Kinase Regulation of the [[NLRP3]] Inflammasome during Aging. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29150317 |full-text-url=https://sci-hub.do/10.1016/j.tem.2017.10.009 }} * {{medline-title |title=Effects of chronically increased VEGF-A on the aging heart. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29146733 |full-text-url=https://sci-hub.do/10.1096/fj.201700761RR }} * {{medline-title |title=[[NLRP3]] inflammasome activation in aged macrophages is diminished during Streptococcus pneumoniae infection. |date=01.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29097427 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900358 }} * {{medline-title |title=Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing. |date=05.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28953873 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718149 }} * {{medline-title |title=Specific calpain inhibition protects kidney against inflammaging. |date=14.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28808241 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556007 }} * {{medline-title |title=Pressor response to angiotensin II is enhanced in aged mice and associated with inflammation, vasoconstriction and oxidative stress. |date=28.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28659507 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509458 }} * {{medline-title |title=The [[NLRP3]] inflammasome contributes to sarcopenia and lower muscle glycolytic potential in old mice. |date=01.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28536183 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582883 }} * {{medline-title |title=Human Plasma Thioredoxin-80 Increases With Age and in ApoE Mice Induces Inflammation, Angiogenesis, and Atherosclerosis. |date=01.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28473446 |full-text-url=https://sci-hub.do/10.1161/CIRCULATIONAHA.117.027612 }} * {{medline-title |title=Metaflammation: Tissue-Specific Alterations of the [[NLRP3]] Inflammasome Platform in Metabolic Syndrome. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28403789 |full-text-url=https://sci-hub.do/10.2174/0929867324666170407123522 }} * {{medline-title |title=Papilloma-pseudovirus eradicates intestinal tumours and triples the lifespan of Apc mice. |date=11.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28397782 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394268 }} * {{medline-title |title=β-Hydroxybutyrate Deactivates Neutrophil [[NLRP3]] Inflammasome to Relieve Gout Flares. |date=28.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28249154 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527297 }} * {{medline-title |title=Vascular endothelial cells senescence is associated with NOD-like receptor family pyrin domain-containing 3 ([[NLRP3]]) inflammasome activation via reactive oxygen species (ROS)/thioredoxin-interacting protein ([[TXNIP]]) pathway. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28064010 |full-text-url=https://sci-hub.do/10.1016/j.biocel.2017.01.001 }} * {{medline-title |title=Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27845246 |full-text-url=https://sci-hub.do/10.1016/j.bbalip.2016.11.003 }} * {{medline-title |title=Aging-Associated [[TNF]] Production Primes Inflammasome Activation and [[NLRP3]]-Related Metabolic Disturbances. |date=01.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27566828 |full-text-url=https://sci-hub.do/10.4049/jimmunol.1501336 }} * {{medline-title |title=Hepatic NAD( ) deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27174364 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945761 }} * {{medline-title |title=Age-Dependent Susceptibility to Pulmonary Fibrosis Is Associated with [[NLRP3]] Inflammasome Activation. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26933834 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979364 }} * {{medline-title |title=Increased VEGF-A promotes multiple distinct aging diseases of the eye through shared pathomechanisms. |date=01.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912740 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772957 }} * {{medline-title |title=Growth Hormone Receptor Deficiency Protects against Age-Related [[NLRP3]] Inflammasome Activation and Immune Senescence. |date=23.02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26876170 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992590 }} * {{medline-title |title=Same molecule but different expression: aging and sepsis trigger [[NLRP3]] inflammasome activation, a target of melatonin. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26681113 |full-text-url=https://sci-hub.do/10.1111/jpi.12303 }} * {{medline-title |title=Nod-like receptor pyrin containing 3 ([[NLRP3]]) in the post-mortem frontal cortex from patients with bipolar disorder: A potential mediator between mitochondria and immune-activation. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26540403 |full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2015.10.015 }} * {{medline-title |title=Gene expression of inflammasome components in peripheral blood mononuclear cells (PBMC) of vascular patients increases with age. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448778 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596365 }} * {{medline-title |title=A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26379247 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575031 }} * {{medline-title |title=Purple sweet potato color inhibits endothelial premature senescence by blocking the [[NLRP3]] inflammasome. |date=10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26164602 |full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2015.04.012 }} * {{medline-title |title=Age-related increases in amyloid beta and membrane attack complex: evidence of inflammasome activation in the rodent eye. |date=24.06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26104676 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486438 }} * {{medline-title |title=A chimeric Cfh transgene leads to increased retinal oxidative stress, inflammation, and accumulation of activated subretinal microglia in mice. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26030099 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464010 }} * {{medline-title |title=Drivers of age-related inflammation and strategies for healthspan extension. |date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25879284 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400872 }} * {{medline-title |title=DAMPs as mediators of sterile inflammation in aging-related pathologies. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25641058 |full-text-url=https://sci-hub.do/10.1016/j.arr.2015.01.003 }} * {{medline-title |title=Protective effect of telmisartan on neurovascular unit and inflammasome in stroke-resistant spontaneously hypertensive rats. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25591419 |full-text-url=https://sci-hub.do/10.1179/1743132815Y.0000000002 }} ==TLR4== * {{medline-title |title=Age-Dependent Changes of Adipokine and Cytokine Secretion From Rat Adipose Tissue by Endogenous and Exogenous Toll-Like Receptor Agonists. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32973755 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466552 }} * {{medline-title |title=Role of Toll Like Receptor 4 in Alzheimer's Disease. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32983082 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479089 }} * {{medline-title |title=Commentary on Some Recent Theses Relevant to Combating Aging: August 2020. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32718230 |full-text-url=https://sci-hub.do/10.1089/rej.2020.2378 }} * {{medline-title |title=Sialylation and Galectin-3 in Microglia-Mediated Neuroinflammation and Neurodegeneration. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32581723 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296093 }} * {{medline-title |title=Chemerin facilitates intervertebral disc degeneration via [[TLR4]] and CMKLR1 and activation of NF-kB signaling pathway. |date=11.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32526705 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343479 }} * {{medline-title |title=Toll-like receptor 4 differentially regulates adult hippocampal neurogenesis in an age- and sex-dependent manner. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32343455 |full-text-url=https://sci-hub.do/10.1002/hipo.23209 }} * {{medline-title |title=Aging-associated immunosenescence via alterations in splenic immune cell populations in rat. |date=15.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31838133 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.117168 }} * {{medline-title |title=Leptin induces immunosenescence in human B cells. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31831137 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002206 }} * {{medline-title |title=Genetic Variation in the Magnitude and Longevity of the IgG Subclass Response to a Diphtheria-Tetanus-Acellular Pertussis (DTaP) Vaccine in Mice. |date=20.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31547158 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963843 }} * {{medline-title |title=Rapamycin improves sevoflurane‑induced cognitive dysfunction in aged rats by mediating autophagy through the [[TLR4]]/MyD88/NF‑κB signaling pathway. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31432123 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755174 }} * {{medline-title |title=Targeting [[HMGB1]] by ethyl pyruvate ameliorates systemic lupus erythematosus and reverses the senescent phenotype of bone marrow-mesenchymal stem cells. |date=14.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31303606 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660056 }} * {{medline-title |title=Age-dependent effect between [[MARCO]] and [[TLR4]] on PMMA particle phagocytosis by macrophages. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225947 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653467 }} * {{medline-title |title=Regulation of Toll-Like Receptor (TLR) Signaling Pathway by Polyphenols in the Treatment of Age-Linked Neurodegenerative Diseases: Focus on [[TLR4]] Signaling. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31134076 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522942 }} * {{medline-title |title=[[TLR4]] Promotes and DAP12 Limits Obesity-Induced Osteoarthritis in Aged Female Mice. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31044181 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478583 }} * {{medline-title |title=Novel Chitohexaose Analog Protects Young and Aged mice from CLP Induced Polymicrobial Sepsis. |date=27.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30814582 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393422 }} * {{medline-title |title=Endothelial toll-like receptor 4 maintains lung integrity via epigenetic suppression of p16 . |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30790400 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516428 }} * {{medline-title |title=Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30659954 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.016 }} * {{medline-title |title=Aging leads to dysfunctional innate immune responses to [[TLR2]] and [[TLR4]] agonists. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30402800 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504629 }} * {{medline-title |title=Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30128650 |full-text-url=https://sci-hub.do/10.1007/s12035-018-1307-2 }} * {{medline-title |title=Ablation of toll-like receptor 4 attenuates aging-induced myocardial remodeling and contractile dysfunction through NCoRI-[[HDAC1]]-mediated regulation of autophagy. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29660306 |full-text-url=https://sci-hub.do/10.1016/j.yjmcc.2018.04.009 }} * {{medline-title |title=Cryopreserved whole blood for the quantification of monocyte, T-cell and NK-cell subsets, and monocyte receptor expression by multi-color flow cytometry: A methodological study based on participants from the canadian longitudinal study on aging. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29624852 |full-text-url=https://sci-hub.do/10.1002/cyto.a.23372 }} * {{medline-title |title=Inflammation, insulin signaling and cognitive function in aged APP/PS1 mice. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29604345 |full-text-url=https://sci-hub.do/10.1016/j.bbi.2018.03.032 }} * {{medline-title |title=Repeated stimulation by LPS promotes the senescence of DPSCs via [[TLR4]]/MyD88-NF-κB-p53/p21 signaling. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29480340 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021280 }} * {{medline-title |title=Ageing potentiates diet-induced glucose intolerance, β-cell failure and tissue inflammation through [[TLR4]]. |date=09.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29426925 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807311 }} * {{medline-title |title=Fibronectin Containing Extra Domain A Induces Plaque Destabilization in the Innominate Artery of Aged Apolipoprotein E-Deficient Mice. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29326316 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823768 }} * {{medline-title |title=Granzyme A in Human Platelets Regulates the Synthesis of Proinflammatory Cytokines by Monocytes in Aging. |date=01.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29167233 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736423 }} * {{medline-title |title=[[TLR4]] and [[TLR2]] activation is differentially associated with age during Parkinson's disease. |date=01.2018 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{{medline-title |title=Effect of concurrent resistance and sprint training on body composition and cardiometabolic health indicators in masters cyclists. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27807523 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091060 }} * {{medline-title |title=Visit-to-Visit Blood Pressure Variability and Mortality and Cardiovascular Outcomes Among Older Adults: The Health, Aging, and Body Composition Study. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27600581 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225946 }} * {{medline-title |title=Omega-3 polyunsaturated fatty acid supplementation attenuates blood pressure increase at onset of isometric handgrip exercise in healthy young and older humans. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27440746 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962077 }} * {{medline-title |title=Acute resistance exercise with blood flow 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of glufosinate-resistant soybean by pollen-mediated gene flow under field conditions in the region of the genetic origin. |date=17.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33189381 |full-text-url=https://sci-hub.do/10.1016/j.scitotenv.2020.143073 }} * {{medline-title |title=Gestational arsenite exposure augments hepatic tumors of C3H mice by promoting senescence in F1 and [[F2]] offspring via different pathways. |date=01.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33010264 |full-text-url=https://sci-hub.do/10.1016/j.taap.2020.115259 }} * {{medline-title |title=Familial Longevity is Associated with an Attenuated Thyroidal Response to Recombinant Human Thyroid Stimulating Hormone. |date=01.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32303766 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239378 }} * {{medline-title |title=Conclusions from a behavioral aging study on male and female [[F2]] hybrid mice on age-related behavior, buoyancy in 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|title=Multigenerational effects of 4-methylbenzylidene camphor (4-MBC) on the survival, development and reproduction of the marine copepod Tigriopus japonicus. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172130 |full-text-url=https://sci-hub.do/10.1016/j.aquatox.2017.11.008 }} * {{medline-title |title=Effects of Aging on Vocal Fundamental Frequency and Vowel Formants in Men and Women. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28864082 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832520 }} * {{medline-title |title=Is Longevity a Heritable Trait? Evidence for Non-genomic Influence from an Extended Longevity Phenotype of Drosophila melanogaster. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28641508 |full-text-url=https://sci-hub.do/10.2174/1874609810666170615120942 }} * {{medline-title |title=Effects of cold storage on the biological characteristics of Microplitis prodeniae (Hymenoptera: Braconidae). |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28220727 |full-text-url=https://sci-hub.do/10.1017/S0007485317000037 }} * {{medline-title |title=Chronic exposure of zinc oxide nanoparticles causes deviant phenotype in Drosophila melanogaster. |date=05.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28064146 |full-text-url=https://sci-hub.do/10.1016/j.jhazmat.2016.12.040 }} * {{medline-title |title=The Interaction of Lexical Characteristics and Speech Production in Parkinson's Disease. |date=01.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28056148 |full-text-url=https://sci-hub.do/10.1044/2016_JSLHR-S-15-0333 }} * {{medline-title |title=Polyunsaturated fatty acids ameliorate aging via redox-telomere-antioncogene axis. |date=31.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28038469 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352322 }} * {{medline-title |title=Stage dependent nutritional regulation of transgenerational longevity. |date=27.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28035341 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166517 }} * {{medline-title |title=Transgenerational programming of longevity through E(z)-mediated histone H3K27 trimethylation in [i]Drosophila[/i]. |date=25.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27889707 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191882 }} * {{medline-title |title=Correlation between flexural and indirect tensile strength of resin composite cements. |date=04.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27809863 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096060 }} * {{medline-title |title=Effects of aging and freezing/thawing sequence on quality attributes of bovine [i]Mm. gluteus medius[/i] and [i]biceps femoris[/i]. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27488843 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5205614 }} * {{medline-title |title=Active Cigarette Smoking in Cognitively-Normal Elders and Probable Alzheimer's Disease is Associated with Elevated Cerebrospinal Fluid Oxidative Stress Biomarkers. |date=25.07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27472882 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127393 }} * {{medline-title |title=Treatment of Chronic Hepatitis C in the Aged - Does It Impact Life Expectancy? 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|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255829 }} * {{medline-title |title=Traumatic Brain Injury in Aged Mice Induces Chronic Microglia Activation, Synapse Loss, and Complement-Dependent Memory Deficits. |date=26.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30486287 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321529 }} * {{medline-title |title=Dialdehyde cellulose crosslinked poly(vinyl alcohol) hydrogels: Influence of catalyst and crosslinker shelf life. |date=15.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30092989 |full-text-url=https://sci-hub.do/10.1016/j.carbpol.2018.06.035 }} * {{medline-title |title=Effects of Feeding Honey Bees (Hymenoptera: Apidae) With Industrial Sugars Produced by Plants Using Different Photosynthetic Cycles (Carbon [[C3]] and C4) on the Colony Wintering Ability, Lifespan, and Forage Behavior. |date=26.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29982786 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laminae and midvein during leaf senescence and source-sink metabolite management in Brassica napus L. leaves. |date=12.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28992054 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853214 }} * {{medline-title |title=d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic. |date=02.12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28965946 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.09.147 }} * {{medline-title |title=Depletion of the Third Complement Component Ameliorates Age-Dependent Oxidative Stress and Positively Modulates Autophagic Activity in Aged Retinas in a Mouse Model. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928904 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591916 }} * {{medline-title |title=The changing shape of the ISCEV standard pattern onset VEP. 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{{medline-title |title=Normative data for parameters of sagittal spinal alignment in healthy subjects: an analysis of gender specific differences and changes with aging in 626 asymptomatic individuals. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27771788 |full-text-url=https://sci-hub.do/10.1007/s00586-016-4807-7 }} * {{medline-title |title=An Evaluation of Functional Sit-to-Stand Power in Cohorts of Healthy Adults Aged 18-97 Years. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27768504 |full-text-url=https://sci-hub.do/10.1123/japa.2016-0031 }} * {{medline-title |title=A Role for TIC55 as a Hydroxylase of Phyllobilins, the Products of Chlorophyll Breakdown during Plant Senescence. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27655840 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134989 }} * {{medline-title |title=Polyphenolic drug composition based on benzenepolycarboxylic acids (BP-[[C3]]) increases life span and inhibits spontaneous tumorigenesis in female SHR mice. |date=28.08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27574962 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076442 }} * {{medline-title |title=Demographic aspects in cervical vertebral bodies' size and shape ([[C3]]-[[C7]]): a skeletal study. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27544049 |full-text-url=https://sci-hub.do/10.1016/j.spinee.2016.08.022 }} * {{medline-title |title=Genetic factors associated with the development of age-related macular degeneration. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27170480 |full-text-url=https://sci-hub.do/10.1016/j.medici.2016.02.004 }} * {{medline-title |title=Prediction of Cervical Endplate Size: One Size Does Not Fit All. |date=01.05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27135446 |full-text-url=https://sci-hub.do/10.3928/01477447-20160427-11 }} * {{medline-title |title=Age- and Hypertension-Associated Protein Aggregates in Mouse 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recombinant complement component [[C3]]b functional fragment α2MR (α2-macroglobulin receptor) additive on the immune response of juvenile orange-spotted grouper (Epinephelus coioides) after the exposure to cold shock challenge. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25917969 |full-text-url=https://sci-hub.do/10.1016/j.fsi.2015.04.019 }} * {{medline-title |title=Ambient temperature reduction extends lifespan via activating cellular degradation activity in an annual fish (Nothobranchius rachovii). |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25864186 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393827 }} * {{medline-title |title=Serum [[C3]] epimer of 25-hydroxyvitamin D and its determinants in adults: a national health examination survey in Thais. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25868511 |full-text-url=https://sci-hub.do/10.1007/s00198-015-3125-y }} * {{medline-title |title=Co-chaperone p23 regulates C. elegans 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|title=Prediction of Early Postoperative Major Cardiac Events and In-Hospital Mortality in Elderly Hip Fracture Patients: The Role of Different Types of Preoperative Cardiac Abnormalities on Echocardiography Report. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32546993 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266334 }} * {{medline-title |title=[Polymorbidity in elderly patients needing myocardial revascularization (a review article).] |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31800187 }} * {{medline-title |title=Fracture force of [[CAD]]/CAM resin composite crowns after in vitro aging. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31712983 |full-text-url=https://sci-hub.do/10.1007/s00784-019-03099-1 }} * {{medline-title |title=Clinical performance of chairside monolithic lithium disilicate glass-ceramic [[CAD]]-CAM crowns. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31565848 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poultry, and eggs using whole genome sequencing technology in Canada. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30717011 |full-text-url=https://sci-hub.do/10.1016/j.foodres.2018.09.014 }} * {{medline-title |title=Age, Sex, and Cardiovascular Risk Attributable to Lipoprotein Cholesterol Among Chinese Individuals with Coronary Artery Disease: A Case-Control Study. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30720383 |full-text-url=https://sci-hub.do/10.1089/met.2018.0067 }} * {{medline-title |title=Novel biomolecules of ageing, sex differences and potential underlying mechanisms of telomere shortening in coronary artery disease. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30684534 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.020 }} * {{medline-title |title=Age-dependent association of pulse wave velocity with coronary artery disease and myocardial aging in high-risk patients. |date=04.2019 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