Редактирование:
Aging genes 30-39
Перейти к навигации
Перейти к поиску
Внимание:
Вы не вошли в систему. Ваш IP-адрес будет общедоступен, если вы запишете какие-либо изменения. Если вы
войдёте
или
создадите учётную запись
, её имя будет использоваться вместо IP-адреса, наряду с другими преимуществами.
Анти-спам проверка.
Не
заполняйте это!
__NOTOC__ * [[Aging genes 300|Genes with 300 and more publications]] * [[Aging genes 200-299|Genes with 200-299 publications]] * [[Aging genes 100-199|Genes with 100-199 publications]] * [[Aging genes 90-99|Genes with 90-99 publications]] * [[Aging genes 80-89|Genes with 80-89 publications]] * [[Aging genes 70-79|Genes with 70-79 publications]] * [[Aging genes 60-69|Genes with 60-69 publications]] * [[Aging genes 50-59|Genes with 50-59 publications]] * [[Aging genes 40-49|Genes with 40-49 publications]] * [[Aging genes 30-39|Genes with 30-39 publications]] * [[Aging genes 20-29|Genes with 20-29 publications]] * [[Aging genes 10-19|Genes with 10-19 publications]] * [[Aging genes 5-9|Genes with 5-9 publications]] * [[Aging genes 3-4|Genes with 3-4 publications]] * [[Aging genes 1-2|Genes with 1-2 publications]] * [[Aging_genes_A-Z_table]] ==CCL2== * {{medline-title |title=Assessment of neuroinflammation in the aging hippocampus using large-molecule microdialysis: Sex differences and role of purinergic receptors. |date=07.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33166661 |full-text-url=https://sci-hub.do/10.1016/j.bbi.2020.11.013 }} * {{medline-title |title=Metformin alters peripheral blood mononuclear cells (PBMC) senescence biomarkers gene expression in type 2 diabetic patients. |date=01.2021 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33187870 |full-text-url=https://sci-hub.do/10.1016/j.jdiacomp.2020.107758 }} * {{medline-title |title=[[IL1B]] triggers inflammatory cytokine production in bovine oviduct epithelial cells and induces neutrophil accumulation via [[CCL2]]. |date=25.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33099841 |full-text-url=https://sci-hub.do/10.1111/aji.13365 }} * {{medline-title |title=Eosinophils and White Fat: Protection from Worms and Inflammaging. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32718231 |full-text-url=https://sci-hub.do/10.1089/rej.2020.2375 }} * {{medline-title |title=[[CXCL9]] and [[CXCL10]] display an age-dependent profile in Chagas patients: a cohort study of aging in Bambui, Brazil. |date=11.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32393333 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216412 }} * {{medline-title |title=p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to non-nucleoside reverse transcriptase inhibitors. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32272174 |full-text-url=https://sci-hub.do/10.1016/j.antiviral.2020.104784 }} * {{medline-title |title=β1 Integrin regulates adult lung alveolar epithelial cell inflammation. |date=30.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31873073 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098727 }} * {{medline-title |title=Arsenic induces human chondrocyte senescence and accelerates rat articular cartilage aging. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31734849 |full-text-url=https://sci-hub.do/10.1007/s00204-019-02607-2 }} * {{medline-title |title=Klotho-mediated targeting of [[CCL2]] suppresses the induction of colorectal cancer progression by stromal cell senescent microenvironments. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31545552 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822285 }} * {{medline-title |title=Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872008 |full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.03.004 }} * {{medline-title |title=Membrane metallo-endopeptidase mediates cellular senescence induced by oncogenic [[PIK3CA]] accompanied with pro-tumorigenic secretome. |date=01.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30671946 |full-text-url=https://sci-hub.do/10.1002/ijc.32153 }} * {{medline-title |title=Isoflurane anesthesia impairs the expression of immune neuromodulators in the hippocampus of aged mice. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30571762 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301699 }} * {{medline-title |title=Melatonin and inflammation-Story of a double-edged blade. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30242884 |full-text-url=https://sci-hub.do/10.1111/jpi.12525 }} * {{medline-title |title=Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025494 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152523 }} * {{medline-title |title=Urine Cytokine and Chemokine Levels Predict Urinary Tract Infection Severity Independent of Uropathogen, Urine Bacterial Burden, Host Genetics, and Host Age. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891542 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105902 }} * {{medline-title |title=Infiltrating macrophages contribute to age-related neuroinflammation in C57/BL6 mice. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29758231 |full-text-url=https://sci-hub.do/10.1016/j.mad.2018.05.003 }} * {{medline-title |title=Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound Aging of Skeletal Muscles. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760352 |full-text-url=https://sci-hub.do/10.1620/tjem.245.29 }} * {{medline-title |title=Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487806 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824071 }} * {{medline-title |title=Immune senescence and biomarkers profile of Bambuí aged population-based cohort. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29247791 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.12.006 }} * {{medline-title |title=Selected life-extending interventions reduce arterial [[CXCL10]] and macrophage colony-stimulating factor in aged mouse arteries. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28390264 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544385 }} * {{medline-title |title=Strain specificities in cellular and molecular immunopathogenic mechanisms underlying development of experimental autoimmune encephalomyelitis in aged rats. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28284714 |full-text-url=https://sci-hub.do/10.1016/j.mad.2017.03.001 }} * {{medline-title |title=Advanced atherosclerosis is associated with inflammation, vascular dysfunction and oxidative stress, but not hypertension. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28017665 |full-text-url=https://sci-hub.do/10.1016/j.phrs.2016.12.032 }} * {{medline-title |title=An attenuated immune response by Schwann cells and macrophages inhibits nerve regeneration in aged rats. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27459920 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2016.05.004 }} * {{medline-title |title=Enhanced Ccl2-Ccr2 signaling drives more severe choroidal neovascularization with aging. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26973110 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2015.12.019 }} * {{medline-title |title=Agmatine Ameliorates High Glucose-Induced Neuronal Cell Senescence by Regulating the p21 and p53 Signaling. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26924930 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766111 }} * {{medline-title |title=Alterations in Monocyte Phenotypes and Functions after a Hip Fracture in Elderly Individuals: A 6-Month Longitudinal Study. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26812523 |full-text-url=https://sci-hub.do/10.1159/000443142 }} * {{medline-title |title=Elevated Levels of Microbial Translocation Markers and [[CCL2]] Among Older HIV-1-Infected Men. |date=01.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26494772 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747622 }} * {{medline-title |title=[[APOE]] Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration. |date=07.10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26446211 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605380 }} * {{medline-title |title=Colorectal cancer-promoting activity of the senescent peritoneal mesothelium. |date=06.10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26284488 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745719 }} * {{medline-title |title=Nilotinib and bosutinib modulate pre-plaque alterations of blood immune markers and neuro-inflammation in Alzheimer's disease models. |date=24.09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26235435 |full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2015.07.070 }} * {{medline-title |title=Neuroimmune and Neuropathic Responses of Spinal Cord and Dorsal Root Ganglia in Middle Age. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26241743 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524632 }} * {{medline-title |title=Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26011191 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444306 }} * {{medline-title |title=[[CCL2]], [[CXCL8]], [[CXCL9]] and [[CXCL10]] serum levels increase with age but are not altered by treatment with hydroxychloroquine in patients with osteoarthritis of the knees. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25955863 |full-text-url=https://sci-hub.do/10.1111/1756-185X.12589 }} * {{medline-title |title=Senescent dermal fibroblasts enhance stem cell migration through [[CCL2]]/[[CCR2]] axis. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25808810 |full-text-url=https://sci-hub.do/10.1111/exd.12701 }} * {{medline-title |title=Age-associated changes in basal NF-κB function in human CD4 T lymphocytes via dysregulation of PI3 kinase. |date=11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25553802 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276789 }} * {{medline-title |title=IL-4 signaling drives a unique arginase /IL-1β microglia phenotype and recruits macrophages to the inflammatory CNS: consequences of age-related deficits in IL-4Rα after traumatic spinal cord injury. |date=25.06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24966389 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069360 }} * {{medline-title |title=Systemic inflammation impairs attention and cognitive flexibility but not associative learning in aged rats: possible implications for delirium. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24959140 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050637 }} * {{medline-title |title=Impaired innate mucosal immunity in aged mice permits prolonged Streptococcus pneumoniae colonization. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24082075 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837976 }} * {{medline-title |title=Effects of ethanol on immune response in the brain: region-specific changes in adolescent versus adult mice. |date=02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24033454 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872252 }} ==CD14== * {{medline-title |title=Human innate immune cell crosstalk induces melanoma cell senescence. |date=30.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32939325 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470184 }} * {{medline-title |title=Lipopolysaccharide binding protein is associated with CVD risk in older adults. |date=08.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32895891 |full-text-url=https://sci-hub.do/10.1007/s40520-020-01684-z }} * {{medline-title |title=Fusion Potential of Human Osteoclasts In Vitro Reflects Age, Menopause, and In Vivo Bone Resorption Levels of Their Donors-A Possible Involvement of DC-STAMP. |date=02.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32887359 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504560 }} * {{medline-title |title=Changes in salivary microbial sensing proteins [[CD14]] and [[TLR2]] with aging. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32529494 |full-text-url=https://sci-hub.do/10.1007/s00784-020-03274-9 }} * {{medline-title |title=Association of [[CD14]] with incident dementia and markers of brain aging and injury. |date=21.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31818907 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108812 }} * {{medline-title |title=Compromised Bone Healing in Aged Rats Is Associated With Impaired M2 Macrophage Function. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31681320 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813416 }} * {{medline-title |title=Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298565 |full-text-url=https://sci-hub.do/10.1089/cell.2019.0010 }} * {{medline-title |title=Increased monocyte activation with age among HIV-infected long term non-progressor children: implications for early treatment initiation. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31131542 |full-text-url=https://sci-hub.do/10.1111/hiv.12751 }} * {{medline-title |title=Wheat seed ageing viewed through the cellular redox environment and changes in pH. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092082 |full-text-url=https://sci-hub.do/10.1080/10715762.2019.1620226 }} * {{medline-title |title=Senescent Phenotype Induced by p90RSK-NRF2 Signaling Sensitizes Monocytes and Macrophages to Oxidative Stress in HIV-Positive Individuals. |date=26.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30586719 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957233 }} * {{medline-title |title=Effects of pepsin and pepstatin on reflux tonsil hypertrophy in vitro. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30408092 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224077 }} * {{medline-title |title=Innate and adaptive immune dysregulation in critically ill ICU patients. |date=05.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29976949 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033948 }} * {{medline-title |title=Serum Zonulin and Endotoxin Levels in Exceptional Longevity versus Precocious Myocardial Infarction. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29896420 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963352 }} * {{medline-title |title=Rapid Turnover and High Production Rate of Myeloid Cells in Adult Rhesus Macaques with Compensations during Aging. |date=15.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29728510 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263173 }} * {{medline-title |title=Human colostrum action against Giardia lamblia infection influenced by hormones and advanced maternal age. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656328 |full-text-url=https://sci-hub.do/10.1007/s00436-018-5860-4 }} * {{medline-title |title=The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence. |date=15.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29449647 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833376 }} * {{medline-title |title=Aged Chinese-origin rhesus macaques infected with SIV develop marked viremia in absence of clinical disease, inflammation or cognitive impairment. |date=01.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29391069 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796498 }} * {{medline-title |title=Stem Cells and Progenitors in Human Peripheral Blood Get Activated by Extremely Active Resveratrol (XAR™). |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177909 |full-text-url=https://sci-hub.do/10.1007/s12015-017-9784-7 }} * {{medline-title |title=Acute Effects of Nitrate-Rich Beetroot Juice on Blood Pressure, Hemostasis and Vascular Inflammation Markers in Healthy Older Adults: A Randomized, Placebo-Controlled Crossover Study. |date=22.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29165355 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707742 }} * {{medline-title |title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277 |full-text-url=https://sci-hub.do/10.1111/rda.13091 }} * {{medline-title |title=Latent Cytomegalovirus (CMV) Infection Does Not Detrimentally Alter T Cell Responses in the Healthy Old, But Increased Latent CMV Carriage Is Related to Expanded CMV-Specific T Cells. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28694811 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483450 }} * {{medline-title |title=HIV and Obesity Comorbidity Increase Interleukin 6 but Not Soluble [[CD14]] or D-Dimer. |date=15.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28696344 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513170 }} * {{medline-title |title=Immunosenescence Induced by Plasma from Individuals with Obesity Caused Cell Signaling Dysfunction and Inflammation. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28707376 |full-text-url=https://sci-hub.do/10.1002/oby.21888 }} * {{medline-title |title=β -Microglobulin participates in development of lung emphysema by inducing lung epithelial cell senescence. |date=01.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28213472 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451601 }} * {{medline-title |title=Age-dependent cellular reactions of the human immune system of humanized NOD scid gamma mice on LPS stimulus. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28162006 |full-text-url=https://sci-hub.do/10.1177/1753425917690814 }} * {{medline-title |title=Immune Activation and Bacterial Translocation: A Link between Impaired Immune Recovery and Frequent Visceral Leishmaniasis Relapses in HIV-Infected Patients. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27907136 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132299 }} * {{medline-title |title=Impaired phagocytosis of apoptotic cells causes accumulation of bone marrow-derived macrophages in aged mice. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27866511 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319664 }} * {{medline-title |title=Do Biomarkers of Inflammation, Monocyte Activation, and Altered Coagulation Explain Excess Mortality Between HIV Infected and Uninfected People? |date=01.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27824677 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867134 }} * {{medline-title |title=Strain-dependent response to stimulation in middle-aged rat macrophages: A quest after a useful indicator of healthy aging. |date=01.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27756630 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.10.005 }} * {{medline-title |title=Distinct inflammatory phenotypes of microglia and monocyte-derived macrophages in Alzheimer's disease models: effects of aging and amyloid pathology. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27723233 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242297 }} * {{medline-title |title=Red Wine Prevents the Acute Negative Vascular Effects of Smoking. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27633722 |full-text-url=https://sci-hub.do/10.1016/j.amjmed.2016.08.025 }} * {{medline-title |title=T-Cell Activation Independently Associates With Immune Senescence in HIV-Infected Recipients of Long-term Antiretroviral Treatment. |date=15.07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27073222 |full-text-url=https://sci-hub.do/10.1093/infdis/jiw146 }} * {{medline-title |title=Cytomegalovirus viral load within blood increases markedly in healthy people over the age of 70 years. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26734066 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700608 }} * {{medline-title |title=Elevated Levels of Microbial Translocation Markers and [[CCL2]] Among Older HIV-1-Infected Men. |date=01.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26494772 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747622 }} * {{medline-title |title=Persistent Immune Activation and Carotid Atherosclerosis in HIV-Infected Ugandans Receiving Antiretroviral Therapy. |date=01.02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26347573 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704672 }} * {{medline-title |title=Visceral leishmaniasis as an independent cause of high immune activation, T-cell senescence, and lack of immune recovery in virologically suppressed HIV-1-coinfected patients. |date=04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25604328 |full-text-url=https://sci-hub.do/10.1111/hiv.12206 }} * {{medline-title |title=Aging oppositely affects [[TNF]]-α and IL-10 production by macrophages from different rat strains. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25009084 |full-text-url=https://sci-hub.do/10.1007/s10522-014-9513-4 }} * {{medline-title |title=Age-related changes in the features of porcine adult stem cells isolated from adipose tissue and skeletal muscle. |date=01.10.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23864607 |full-text-url=https://sci-hub.do/10.1152/ajpcell.00151.2013 }} * {{medline-title |title=Lower levels of circulating progenitor cells are associated with low physical function and performance in elderly men with impaired glucose tolerance: a pilot substudy from the VA Enhanced Fitness trial. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23682163 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814238 }} ==CORT== * {{medline-title |title=Sex differences in body composition, metabolism-related hormones, and energy homeostasis during aging in Wistar rats. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33075214 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571994 }} * {{medline-title |title=Effects of age and social isolation on murine hippocampal biochemistry and behavior. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32866520 |full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111337 }} * {{medline-title |title=Interleukin 6 reduces allopregnanolone synthesis in the brain and contributes to age-related cognitive decline in mice. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32669383 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529050 }} * {{medline-title |title=Sex- and age-dependent differences in the hormone and drinking responses to water deprivation. |date=01.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31967852 |full-text-url=https://sci-hub.do/10.1152/ajpregu.00303.2019 }} * {{medline-title |title=Ontogeny of the adrenocortical response in an extremely altricial bird. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31545013 |full-text-url=https://sci-hub.do/10.1002/jez.2317 }} * {{medline-title |title=Exposure to jet lag aggravates depression-like behaviors and age-related phenotypes in rats subject to chronic corticosterone. |date=05.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31314053 |full-text-url=https://sci-hub.do/10.1093/abbs/gmz070 }} * {{medline-title |title=Hyperadrenocorticism of calorie restriction contributes to its anti-inflammatory action in mice. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30938024 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516174 }} * {{medline-title |title=Effect of chronic corticosterone-induced depression on circadian rhythms and age-related phenotypes in mice. |date=01.12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30395149 |full-text-url=https://sci-hub.do/10.1093/abbs/gmy132 }} * {{medline-title |title=Early Life Stress Strengthens Trait Covariance: A Plastic Response That Results in Reduced Flexibility. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30332583 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414225 }} * {{medline-title |title=Both Basal and Acute Restraint Stress-Induced c-Fos Expression Is Influenced by Age in the Extended Amygdala and Brainstem Stress Centers in Male Rats. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30186150 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113579 }} * {{medline-title |title=Stress-induced corticosterone secretion covaries with working memory in aging. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30144648 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162104 }} * {{medline-title |title=Sex-specific differences in corticosterone secretion, behavioral phenotypes and expression of TrkB.T1 and TrkB.FL receptor isoforms: Impact of systemic TrkB inhibition and combinatory stress exposure in adolescence. |date=30.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29753050 |full-text-url=https://sci-hub.do/10.1016/j.pnpbp.2018.05.002 }} * {{medline-title |title=Lifelong Aerobic Exercise Reduces the Stress Response in Rats. |date=15.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29462703 |full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2018.02.019 }} * {{medline-title |title=sst -receptor gene deletion exacerbates chronic stress-induced deficits: Consequences for emotional and cognitive ageing. |date=30.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29409919 |full-text-url=https://sci-hub.do/10.1016/j.pnpbp.2018.01.022 }} * {{medline-title |title=Chronic corticosterone-induced depression mediates premature aging in rats. |date=15.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29329057 |full-text-url=https://sci-hub.do/10.1016/j.jad.2017.12.073 }} * {{medline-title |title=Effects of developmental conditions on glucocorticoid concentrations in adulthood depend on sex and foraging conditions. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28576645 |full-text-url=https://sci-hub.do/10.1016/j.yhbeh.2017.05.020 }} * {{medline-title |title=Corticosterone Response as an Age-Specific Mediator of Nestling Body Mass in a Wild Passerine. |date=07-08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28548900 |full-text-url=https://sci-hub.do/10.1086/692631 }} * {{medline-title |title=Impact of transportation duration on stress responses in day-old chicks from young and old breeders. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28458107 |full-text-url=https://sci-hub.do/10.1016/j.rvsc.2017.04.015 }} * {{medline-title |title=Long-term effects of adolescent stress on neophobic behaviors in zebra finches are modulated by social context when in adulthood. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28167135 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415300 }} * {{medline-title |title=A chronic increase of corticosterone age-dependently reduces systemic DNA damage from oxidation in rats. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28069523 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2017.01.013 }} * {{medline-title |title=Prenatal betaine exposure alleviates corticosterone-induced inhibition of [[CYP27A1]] expression in the liver of juvenile chickens associated with its promoter DNA methylation. |date=15.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28039067 |full-text-url=https://sci-hub.do/10.1016/j.ygcen.2016.12.014 }} * {{medline-title |title=Ancestry trumps experience: Transgenerational but not early life stress affects the adult physiological stress response. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27864050 |full-text-url=https://sci-hub.do/10.1016/j.yhbeh.2016.11.010 }} * {{medline-title |title=Chronic corticosterone treatment enhances extinction-induced depression in aged rats. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27633458 |full-text-url=https://sci-hub.do/10.1016/j.yhbeh.2016.09.003 }} * {{medline-title |title=Effects of Ontogeny, Diel Rhythms, and Environmental Variation on the Adrenocortical Physiology of Semialtricial Black Kites (Milvus migrans). |date=05-06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27153131 |full-text-url=https://sci-hub.do/10.1086/684966 }} * {{medline-title |title=Chronic intermittent ethanol exposure during adolescence: Effects on stress-induced social alterations and social drinking in adulthood. |date=01.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27048754 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047849 }} * {{medline-title |title=Adolescent caffeine consumption increases adulthood anxiety-related behavior and modifies neuroendocrine signaling. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26874560 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808446 }} * {{medline-title |title=Short photoperiod condition increases susceptibility to stress in adolescent male rats. |date=01.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26655789 |full-text-url=https://sci-hub.do/10.1016/j.bbr.2015.12.002 }} * {{medline-title |title=Age and sex differences in c-Fos expression and serum corticosterone concentration following LPS treatment. |date=01.10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26117716 |full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2015.06.035 }} * {{medline-title |title=Diurnal and stress-induced intra-hippocampal corticosterone rise attenuated in 11β-HSD1-deficient mice: a microdialysis study in young and aged mice. |date=03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25614240 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440343 }} * {{medline-title |title=A comparison of the short- and long-term effects of corticosterone exposure on extinction in adolescence versus adulthood. |date=12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25314660 |full-text-url=https://sci-hub.do/10.1037/bne0000022 }} * {{medline-title |title=Variation in plasma corticosterone in migratory songbirds: a test of the migration-modulation hypothesis. |date=09-10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25244381 |full-text-url=https://sci-hub.do/10.1086/676937 }} * {{medline-title |title=Calorie restriction and corticosterone elevation during lactation can each modulate adult male fear and anxiety-like behaviour. |date=09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25205316 |full-text-url=https://sci-hub.do/10.1016/j.yhbeh.2014.08.013 }} * {{medline-title |title=Age-dependent effect of high cholesterol diets on anxiety-like behavior in elevated plus maze test in rats. |date=01.09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25179125 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158000 }} * {{medline-title |title=Intrahippocampal glucocorticoids generated by 11β-HSD1 affect memory in aged mice. |date=01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25109766 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706164 }} * {{medline-title |title=Age-dependent sensitivity to glucocorticoids in the developing mouse basolateral nucleus of the amygdala. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24882159 |full-text-url=https://sci-hub.do/10.1016/j.psyneuen.2014.04.007 }} * {{medline-title |title=Maternal effects underlie ageing costs of growth in the zebra finch (Taeniopygia guttata). |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24828412 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020873 }} * {{medline-title |title=Serotonin and corticosterone rhythms in mice exposed to cigarette smoke and in patients with COPD: implication for COPD-associated neuropathogenesis. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24520342 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919731 }} * {{medline-title |title=Glucocorticoid-dependent hippocampal transcriptome in male rats: pathway-specific alterations with aging. |date=08.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23736296 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713214 }} * {{medline-title |title=Stress hormones mediate predator-induced phenotypic plasticity in amphibian tadpoles. |date=07.05.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23466985 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619459 }} ==ATR== * {{medline-title |title=[[REV1]] inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks. |date=17.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168727 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682577 }} * {{medline-title |title=Bloodstain age estimation through infrared spectroscopy and Chemometric models. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33077037 |full-text-url=https://sci-hub.do/10.1016/j.scijus.2020.07.004 }} * {{medline-title |title=Artificial Intelligence and fourier-transform infrared spectroscopy for evaluating water-mediated degradation of lubricant oils. |date=01.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32887052 |full-text-url=https://sci-hub.do/10.1016/j.talanta.2020.121312 }} * {{medline-title |title=Senescence Induction by Combined Ionizing Radiation and DNA Damage Response Inhibitors in Head and Neck Squamous Cell Carcinoma Cells. |date=01.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32883016 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563880 }} * {{medline-title |title=Kinetics of thermal degradation and lifetime study of poly(vinylidene fluoride) (PVDF) subjected to bioethanol fuel accelerated aging. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32775731 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398943 }} * {{medline-title |title=Supraphysiological protection from replication stress does not extend mammalian lifespan. |date=06.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32253367 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185120 }} * {{medline-title |title=Assessing the Retest Reliability of Prefrontal EEG Markers of Brain Rhythm Slowing in the Eyes-Closed Resting State. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32253926 |full-text-url=https://sci-hub.do/10.1177/1550059420914832 }} * {{medline-title |title=Effects of Hydrogen Peroxide and Sodium Hypochlorite Aging on Properties and Performance of Polyethersulfone Ultrafiltration Membrane. |date=18.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31635217 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843545 }} * {{medline-title |title=NF-κB signaling in skin aging. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31634486 |full-text-url=https://sci-hub.do/10.1016/j.mad.2019.111160 }} * {{medline-title |title=Development of a w/o emulsion using ionic liquid strategy for transdermal delivery of anti - aging component α - lipoic acid: Mechanism of different ionic liquids on skin retention and efficacy evaluation. |date=01.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31634554 |full-text-url=https://sci-hub.do/10.1016/j.ejps.2019.105042 }} * {{medline-title |title=Effect of Nitrogen-Doped Graphene Oxide on the Aging Behavior of Nitrile-Butadiene Rubber. |date=10.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31658636 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835680 }} * {{medline-title |title=Age-related dysfunction of the DNA damage response in intestinal stem cells. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31057688 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485179 }} * {{medline-title |title=Age-related variations in corneal geometry and their association with astigmatism: The Yamagata Study (Funagata). |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30412088 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221551 }} * {{medline-title |title=Sex-related differences in corneal astigmatism and shape with age. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30077353 |full-text-url=https://sci-hub.do/10.1016/j.jcrs.2018.06.020 }} * {{medline-title |title=Aging-Resistant Functionalized LDH⁻SAS/Nitrile-Butadiene Rubber Composites: Preparation and Study of Aging Kinetics/Anti-Aging Mechanism. |date=18.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29783656 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978213 }} * {{medline-title |title=[Protective effect of Wuzi Yanzong recipe on testicular DNA damage and apoptosis in natural ageing rats]. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29751716 |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180115.005 }} * {{medline-title |title=Age-related changes in with-the-rule and oblique corneal astigmatism. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29369508 |full-text-url=https://sci-hub.do/10.1111/aos.13683 }} * {{medline-title |title=Investigation of the factors that influence lead accumulation onto polyethylene: Implication for potable water plumbing pipes. |date=05.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29324324 |full-text-url=https://sci-hub.do/10.1016/j.jhazmat.2017.12.066 }} * {{medline-title |title=Global mapping of transcription factor motifs in human aging. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29293662 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749797 }} * {{medline-title |title=Cross-Sectional and Longitudinal Investigation of the Power Vector in Astigmatism: The Yamagata Study (Funagata). |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29095754 |full-text-url=https://sci-hub.do/10.1097/ICO.0000000000001418 }} * {{medline-title |title=Glomerular and tubular effects of nitric oxide (NO) are regulated by angiotensin II (Ang II) in an age-dependent manner through activation of both angiotensin receptors (AT1Rs and AT2Rs) in conscious lambs. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28861607 |full-text-url=https://sci-hub.do/10.1007/s00424-017-2053-4 }} * {{medline-title |title=Progerin-Induced Replication Stress Facilitates Premature Senescence in Hutchinson-Gilford Progeria Syndrome. |date=15.07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28483909 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492170 }} * {{medline-title |title=Increasing age in Achilles rupture patients over time. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28457569 |full-text-url=https://sci-hub.do/10.1016/j.injury.2017.04.007 }} * {{medline-title |title=Phospholipid-protein balance in affective disorders: Analysis of human blood serum using Raman and FTIR spectroscopy. A pilot study. |date=30.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27614042 |full-text-url=https://sci-hub.do/10.1016/j.jpba.2016.08.037 }} * {{medline-title |title=Dysfunctional telomeres induce p53-dependent and independent apoptosis to compromise cellular proliferation and inhibit tumor formation. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27113195 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933665 }} * {{medline-title |title=Relationship between age, corneal astigmatism, and ocular dimensions with reference to astigmatism in eyes undergoing routine cataract surgery. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26795412 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108535 }} * {{medline-title |title=The DNA damage response induces inflammation and senescence by inhibiting autophagy of [[GATA4]]. |date=25.09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26404840 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942138 }} * {{medline-title |title=Analysis of anterior corneal astigmatism before cataract surgery using power vector analysis in eyes of Korean patients. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26189381 |full-text-url=https://sci-hub.do/10.1016/j.jcrs.2014.09.043 }} * {{medline-title |title=Requirement of [[ATR]] for maintenance of intestinal stem cells in aging Drosophila. |date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26000719 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468312 }} * {{medline-title |title=Ambient temperature reduction extends lifespan via activating cellular degradation activity in an annual fish (Nothobranchius rachovii). |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25864186 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393827 }} * {{medline-title |title=Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of [[ATR]] mutant mice. |date=01.04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25838540 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387711 }} * {{medline-title |title=Structural investigation of donor age effect on human bone marrow mesenchymal stem cells: FTIR spectroscopy and imaging. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25081108 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150902 }} * {{medline-title |title=Gestational and lactational exposure to atrazine via the drinking water causes specific behavioral deficits and selectively alters monoaminergic systems in C57BL/6 mouse dams, juvenile and adult offspring. |date=09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24913803 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184358 }} * {{medline-title |title=Age-dependent dopaminergic dysfunction following fetal exposure to atrazine in SD rats. |date=05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24863964 |full-text-url=https://sci-hub.do/10.1016/j.etap.2014.04.023 }} * {{medline-title |title=Molecular characterization of collaborator of ARF ([[CARF]]) as a DNA damage response and cell cycle checkpoint regulatory protein. |date=01.04.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24485912 |full-text-url=https://sci-hub.do/10.1016/j.yexcr.2014.01.022 }} * {{medline-title |title=p16(INK4a) protects against dysfunctional telomere-induced [[ATR]]-dependent DNA damage responses. |date=10.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24091330 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784543 }} * {{medline-title |title=Caenorhabditis elegans [[ATR]] checkpoint kinase ATL-1 influences life span through mitochondrial maintenance. |date=11.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23434802 |full-text-url=https://sci-hub.do/10.1016/j.mito.2013.02.004 }} * {{medline-title |title=Small molecule inhibition of p38 MAP kinase extends the replicative life span of human [[ATR]]-Seckel syndrome fibroblasts. |date=09.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23401567 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738025 }} ==CCK== * {{medline-title |title=Senolytic agent Quercetin ameliorates intervertebral disc degeneration via the Nrf2/NF-κB axis. |date=23.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33242601 |full-text-url=https://sci-hub.do/10.1016/j.joca.2020.11.006 }} * {{medline-title |title=Astragalus improve aging bone marrow mesenchymal stem cells (BMSCs) vitality and osteogenesis through VD-[[FGF23]]-Klotho axis. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32355520 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191145 }} * {{medline-title |title=Effects of Age on Acute Appetite-Related Responses to Whey-Protein Drinks, Including Energy Intake, Gastric Emptying, Blood Glucose, and Plasma Gut Hormone Concentrations-A Randomized Controlled Trial. |date=06.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32268554 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231005 }} * {{medline-title |title=Lactose induced redox-dependent senescence and activated Nrf2 pathway. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31934025 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949649 }} * {{medline-title |title=Quercetin Suppresses the Progression of Atherosclerosis by Regulating [[MST1]]-Mediated Autophagy in ox-LDL-Induced RAW264.7 Macrophage Foam Cells. |date=03.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31816893 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928812 }} * {{medline-title |title=LncRNA AW112010 Promotes Mitochondrial Biogenesis and Hair Cell Survival: Implications for Age-Related Hearing Loss. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31781342 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855056 }} * {{medline-title |title=Effects of age on feeding response: Focus on the rostral C1 neuron and its glucoregulatory proteins. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31705967 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110779 }} * {{medline-title |title=Ser-Tyr and Asn-Ala, vasorelaxing dipeptides found by comprehensive screening, reduce blood pressure via different age-dependent mechanisms. |date=04.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31685714 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874431 }} * {{medline-title |title=Fisetin, via CKIP-1/REGγ, limits oxidized LDL-induced lipid accumulation and senescence in RAW264.7 macrophage-derived foam cells. |date=15.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31655030 |full-text-url=https://sci-hub.do/10.1016/j.ejphar.2019.172748 }} * {{medline-title |title=[Ginsenoside Rg_1 induces leukemia stem cell senescence via [[SIRT1]]/TSC_2 signal axis]. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31359662 |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20190218.002 }} * {{medline-title |title=Chromatin remodeling factor [[BAZ1A]] regulates cellular senescence in both cancer and normal cells. |date=15.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31085244 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.05.023 }} * {{medline-title |title=Circular RNA expression profile in human fibroblast premature senescence after repeated ultraviolet B irradiations revealed by microarray. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30908647 |full-text-url=https://sci-hub.do/10.1002/jcp.28449 }} * {{medline-title |title=Long non-coding RNA-OIS1 inhibits HPV-positive, but not HPV-negative cervical squamous cell carcinoma by upregulating MTK-1. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30854069 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365941 }} * {{medline-title |title=Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30674441 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412871 }} * {{medline-title |title=MiR-34a Enhances Chondrocyte Apoptosis, Senescence and Facilitates Development of Osteoarthritis by Targeting [[DLL1]] and Regulating PI3K/AKT Pathway. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048987 |full-text-url=https://sci-hub.do/10.1159/000492090 }} * {{medline-title |title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528 }} * {{medline-title |title=Apelin/APJ axis improves angiotensin II-induced endothelial cell senescence through AMPK/[[SIRT1]] signaling pathway. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30002688 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040122 }} * {{medline-title |title=Osthole Delays Tert-Butyl Hydroperoxide-Induced Premature Senescence in Neural Stem Cells. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29989446 |full-text-url=https://sci-hub.do/10.1089/cell.2018.0010 }} * {{medline-title |title=N-Cadherin Attenuates High Glucose-Induced Nucleus Pulposus Cell Senescence Through Regulation of the ROS/NF-κB Pathway. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29768261 |full-text-url=https://sci-hub.do/10.1159/000489804 }} * {{medline-title |title=Localization of cholecystokinin in the zebrafish retina from larval to adult stage. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29679719 |full-text-url=https://sci-hub.do/10.1016/j.aanat.2018.01.010 }} * {{medline-title |title=Glutamate-dependent regulation of food intake is altered with age through changes in NMDA receptor phenotypes on vagal afferent neurons. |date=15.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29476874 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058966 }} * {{medline-title |title=Effects of Substitution, and Adding of Carbohydrate and Fat to Whey-Protein on Energy Intake, Appetite, Gastric Emptying, Glucose, Insulin, Ghrelin, [[CCK]] and GLP-1 in Healthy Older Men-A Randomized Controlled Trial. |date=23.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29360778 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852689 }} * {{medline-title |title=Effect of Age on Blood Glucose and Plasma Insulin, Glucagon, Ghrelin, [[CCK]], [[GIP]], and GLP-1 Responses to Whey Protein Ingestion. |date=21.12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29267221 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793230 }} * {{medline-title |title=Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation |date=27.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28952292 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720660 }} * {{medline-title |title=[Effects of ginseng, notoginseng, and Chuanxiong Rhizoma extracts on cytoskeleton protein of replicative senescence vascular smooth muscle cells]. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28868868 |full-text-url=https://sci-hub.do/10.4268/cjcmm20160321 }} * {{medline-title |title=[Inula Britannica flower total flavonoids reduces the apoptosis of aging bone marrow mesenchymal stem cells by anti-oxidation]. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28502304 }} * {{medline-title |title=[The mechanism of bone marrow-derived mesenchymal stem cells excessive senescence in severe aplastic anemia mouse model]. |date=14.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28468095 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342723 }} * {{medline-title |title=Overexpression of miR-584-5p inhibits proliferation and induces apoptosis by targeting WW domain-containing E3 ubiquitin protein ligase 1 in gastric cancer. |date=21.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28431583 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401563 }} * {{medline-title |title=Molecular mechanism of G arrest and cellular senescence induced by LEE011, a novel [[CDK4]]/CDK6 inhibitor, in leukemia cells. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28286417 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340031 }} * {{medline-title |title=Exogenous H2S contributes to recovery of ischemic post-conditioning-induced cardioprotection by decrease of ROS level via down-regulation of NF-κB and [[JAK2]]-[[STAT3]] pathways in the aging cardiomyocytes. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27096074 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836181 }} * {{medline-title |title=Resveratrol attenuates senescence of adipose-derived mesenchymal stem cells and restores their paracrine effects on promoting insulin secretion of [[INS]]-1 cells through Pim-1. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27049278 }} * {{medline-title |title=Cholecystokinin expression in the β-cell leads to increased β-cell area in aged mice and protects from streptozotocin-induced diabetes and apoptosis. |date=15.11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26394663 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652070 }} * {{medline-title |title=Down-Regulated [[NRSN2]] Promotes Cell Proliferation and Survival Through PI3K/Akt/mTOR Pathway in Hepatocellular Carcinoma. |date=10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26055238 |full-text-url=https://sci-hub.do/10.1007/s10620-015-3736-3 }} * {{medline-title |title=The positive effects of Ginsenoside Rg1 upon the hematopoietic microenvironment in a D-Galactose-induced aged rat model. |date=15.04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25881060 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417299 }} * {{medline-title |title=Exposure to a high fat diet during the perinatal period alters vagal motoneurone excitability, even in the absence of obesity. |date=01.01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25556801 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293068 }} * {{medline-title |title=Ionizing irradiation inhibits keloid fibroblast cell proliferation and induces premature cellular senescence. |date=01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25425417 |full-text-url=https://sci-hub.do/10.1111/1346-8138.12702 }} * {{medline-title |title=Age and nutritional state influence the effects of cholecystokinin on energy balance. |date=11.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23876629 |full-text-url=https://sci-hub.do/10.1016/j.exger.2013.07.006 }} * {{medline-title |title=Age-associated changes in pancreatic exocrine secretion of the isolated perfused rat pancreas. |date=03.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23573104 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616205 }} ==FOXO1== * {{medline-title |title=The phytochemical epigallocatechin gallate prolongs the lifespan by improving lipid metabolism, reducing inflammation and oxidative stress in high-fat diet-fed obese rats. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32729662 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511879 }} * {{medline-title |title=Ginsenoside Rg1 protects against d-galactose induced fatty liver disease in a mouse model via [[FOXO1]] transcriptional factor. |date=01.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32437790 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.117776 }} * {{medline-title |title=Gene expression in human mesenchymal stem cell aging cultures: modulation by short peptides. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32399807 |full-text-url=https://sci-hub.do/10.1007/s11033-020-05506-3 }} * {{medline-title |title=l-Theanine attenuates liver aging by inhibiting advanced glycation end products in d-galactose-induced rats and reversing an imbalance of oxidative stress and inflammation. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31899338 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110823 }} * {{medline-title |title=Increased [[REST]] to Optimize Life Span? |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31762373 |full-text-url=https://sci-hub.do/10.1089/rej.2019.2287 }} * {{medline-title |title=Regulation of lifespan by neural excitation and [[REST]]. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31619788 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893853 }} * {{medline-title |title=Herbal Medicine for Slowing Aging and Aging-associated Conditions: Efficacy, Mechanisms and Safety. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31418664 |full-text-url=https://sci-hub.do/10.2174/1570161117666190715121939 }} * {{medline-title |title=Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30537739 |full-text-url=https://sci-hub.do/10.1159/000495895 }} * {{medline-title |title=Functional pathways regulated by microRNA networks in CD8 T-cell aging. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30488559 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351841 }} * {{medline-title |title=Introduction to FOXO Biology. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30414140 |full-text-url=https://sci-hub.do/10.1007/978-1-4939-8900-3_1 }} * {{medline-title |title=Antioxidant modifications induced by the new metformin derivative HL156A regulate metabolic reprogramming in SAMP1/kl (-/-) mice. |date=16.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30222592 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188477 }} * {{medline-title |title=Master athletes have higher miR-7, [[SIRT3]] and [[SOD2]] expression in skeletal muscle than age-matched sedentary controls. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30107294 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092475 }} * {{medline-title |title=[[FOXO1]] and [[ETV6]] genes may represent novel regulators of splicing factor expression in cellular senescence. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30088951 |full-text-url=https://sci-hub.do/10.1096/fj.201801154R }} * {{medline-title |title=Autophagy mediators ([[FOXO1]], [[SESN3]] and [[TSC2]]) in Lewy body disease and aging. |date=25.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966750 |full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.06.052 }} * {{medline-title |title=FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29963746 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156454 }} * {{medline-title |title=Senescence Alters PPARγ (Peroxisome Proliferator-Activated Receptor Gamma)-Dependent Fatty Acid Handling in Human Adipose Tissue Microvascular Endothelial Cells and Favors Inflammation. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29545239 |full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.310797 }} * {{medline-title |title=[[HGF]] and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the [[SIRT1]]/[[FOXO1]] Signaling Pathway. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29462806 |full-text-url=https://sci-hub.do/10.1159/000487559 }} * {{medline-title |title=Role of Forkhead Box O (FOXO) transcription factor in aging and diseases. |date=30.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29428128 |full-text-url=https://sci-hub.do/10.1016/j.gene.2018.01.051 }} * {{medline-title |title=FOXO in Neural Cells and Diseases of the Nervous System. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29433734 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881381 }} * {{medline-title |title=Clearance of senescent decidual cells by uterine natural killer cells in cycling human endometrium. |date=11.12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29227245 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724991 }} * {{medline-title |title=FOXO Transcriptional Factors and Long-Term Living. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28894507 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574317 }} * {{medline-title |title=Aquatide Activation of [[SIRT1]] Reduces Cellular Senescence through a [[SIRT1]]-[[FOXO1]]-Autophagy Axis. |date=01.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28822991 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590795 }} * {{medline-title |title=The protein kinase MBK-1 contributes to lifespan extension in [i]daf-2[/i] mutant and germline-deficient [i]Caenorhabditis elegans[/i]. |date=25.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28562327 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472741 }} * {{medline-title |title=Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-[[FOXO1]] pathway. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28507478 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427465 }} * {{medline-title |title=Caloric restriction delays early phases of carcinogenesis via effects on the tissue microenvironment. |date=30.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28415598 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482635 }} * {{medline-title |title=Age-related reduction in the expression of FOXO transcription factors and correlations with intervertebral disc degeneration. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28430387 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650945 }} * {{medline-title |title=Oxidative Stress-Induced miR-200c Disrupts the Regulatory Loop Among [[SIRT1]], [[FOXO1]], and eNOS. |date=20.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27960536 |full-text-url=https://sci-hub.do/10.1089/ars.2016.6643 }} * {{medline-title |title=miR-96, miR-145 and miR-9 expression increases, and IGF-1R and [[FOXO1]] expression decreases in peripheral blood mononuclear cells of aging humans. |date=30.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27903254 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131432 }} * {{medline-title |title=Cone Viability Is Affected by Disruption of Melatonin Receptors Signaling. |date=01.01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26780313 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727519 }} * {{medline-title |title=Effect of Aging on Periodontal Inflammation, Microbial Colonization, and Disease Susceptibility. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26762510 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802783 }} * {{medline-title |title=Long live FOXO: unraveling the role of FOXO proteins in aging and longevity. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26643314 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783344 }} * {{medline-title |title=Abrogation of Age-Induced MicroRNA-195 Rejuvenates the Senescent Mesenchymal Stem Cells by Reactivating Telomerase. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26390028 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797648 }} * {{medline-title |title=Endogenous ROS levels are increased in replicative senescence in human bone marrow mesenchymal stromal cells. |date=15.05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25839657 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.03.136 }} * {{medline-title |title=Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis. |date=01.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24269635 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932989 }} * {{medline-title |title=Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons. |date=09.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23851366 |full-text-url=https://sci-hub.do/10.4161/auto.25188 }} * {{medline-title |title=Age-related changes of forkhead transcription factor [[FOXO1]] in the liver of senescence-accelerated mouse SAMP8. |date=11-12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23806789 |full-text-url=https://sci-hub.do/10.1016/j.archger.2013.06.004 }} * {{medline-title |title=Progesterone receptors induce [[FOXO1]]-dependent senescence in ovarian cancer cells. |date=01.05.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23574718 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674071 }} * {{medline-title |title=[[SIRT3]] overexpression antagonizes high glucose accelerated cellular senescence in human diploid fibroblasts via the [[SIRT3]]-[[FOXO1]] signaling pathway. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23494737 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825003 }} ==MYC== * {{medline-title |title=A Small Molecule Stabilizer of the [[MYC]] G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma. |date=13.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066043 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650714 }} * {{medline-title |title=Enhanced proliferative capacity of human preadipocytes achieved by an optimized cultivating method that induces transient activity of hTERT. |date=20.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32703451 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.06.019 }} * {{medline-title |title=Collaboration of [[MYC]] and [[RUNX2]] in lymphoma simulates T-cell receptor signaling and attenuates p53 pathway activity. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31257681 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772115 }} * {{medline-title |title=Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes. |date=13.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31200451 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627600 }} * {{medline-title |title=Transcriptomic analysis of human IL-7 receptor alpha and effector memory CD8 T cells reveals an age-associated signature linked to influenza vaccine response in older adults. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31044512 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612637 }} * {{medline-title |title=[[SLC1A5]] glutamine transporter is a target of [[MYC]] and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30909319 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516164 }} * {{medline-title |title=Profound, durable and [[MGMT]]-independent sensitivity of glioblastoma cells to cyclin-dependent kinase inhibition. |date=01.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30549269 |full-text-url=https://sci-hub.do/10.1002/ijc.32069 }} * {{medline-title |title=[[MYC]] and RAS are unable to cooperate in overcoming cellular senescence and apoptosis in normal human fibroblasts. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526305 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343716 }} * {{medline-title |title=A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation. |date=02.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279449 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168501 }} * {{medline-title |title=O-GlcNAcylation is required for mutant [[KRAS]]-induced lung tumorigenesis. |date=01.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30130254 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205381 }} * {{medline-title |title=Centenarians Overexpress Pluripotency-Related Genes. |date=16.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797 |full-text-url=https://sci-hub.do/10.1093/gerona/gly168 }} * {{medline-title |title=E47 Governs the [[MYC]]-CDKN1B/p27 -RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16 and Wild-Type p53. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003124 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039985 }} * {{medline-title |title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201 }} * {{medline-title |title=[[MYC]] Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition. |date=10.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29641997 |full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.03.057 }} * {{medline-title |title=Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage- and Histone Methylation-Dependent Pathways. |date=27.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29590617 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915310 }} * {{medline-title |title=Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older adults. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29383869 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847877 }} * {{medline-title |title=Modulation of dietary folate with age confers selective hepatocellular epigenetic imprints through DNA methylation. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29220669 |full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2017.10.007 }} * {{medline-title |title=Proline Metabolism in Cell Regulation and Cancer Biology: Recent Advances and Hypotheses. |date=01.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28990419 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338564 }} * {{medline-title |title=[[MYC]] Modulation around the CDK2/p27/SKP2 Axis. |date=30.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28665315 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541307 }} * {{medline-title |title=Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts. |date=01.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28635509 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576272 }} * {{medline-title |title=Nickel-induced HIF-1α promotes growth arrest and senescence in normal human cells but lacks toxic effects in transformed cells. |date=15.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28552779 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568485 }} * {{medline-title |title=Role of p16 and BMI-1 in oxidative stress-induced premature senescence in human dental pulp stem cells. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28410532 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390672 }} * {{medline-title |title=The RUNX Genes as Conditional Oncogenes: Insights from Retroviral Targeting and Mouse Models. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28299662 |full-text-url=https://sci-hub.do/10.1007/978-981-10-3233-2_16 }} * {{medline-title |title=Protection against High-Fat-Diet-Induced Obesity in [[MDM2]] Mice Due to Reduced p53 Activity and Enhanced Energy Expenditure. |date=24.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28122227 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560502 }} * {{medline-title |title=Downregulation of [[CITED2]] contributes to TGFβ-mediated senescence of tendon-derived stem cells. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28084522 |full-text-url=https://sci-hub.do/10.1007/s00441-016-2552-1 }} * {{medline-title |title=[[STAT3]]-mediated [[SMAD3]] activation underlies Oncostatin M-induced Senescence. |date=16.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27892764 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324753 }} * {{medline-title |title=Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans. |date=15.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27654940 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157077 }} * {{medline-title |title=Bromodomain and Extraterminal Protein Inhibition Blocks Growth of Triple-negative Breast Cancers through the Suppression of Aurora Kinases. |date=04.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27650498 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095428 }} * {{medline-title |title=Mitochondrial function in hypoxic ischemic injury and influence of aging. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27321753 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161736 }} * {{medline-title |title=JAZ7 negatively regulates dark-induced leaf senescence in Arabidopsis. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26547795 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737072 }} * {{medline-title |title=ARF: connecting senescence and innate immunity for clearance. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26412380 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600620 }} * {{medline-title |title=Reduced expression of [[MYC]] increases longevity and enhances healthspan. |date=29.01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25619689 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624921 }} * {{medline-title |title=Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25485586 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613853 }} * {{medline-title |title=DNA and RNA quadruplex-binding proteins. |date=29.09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25268620 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227175 }} * {{medline-title |title=Aging and injury: alterations in cellular energetics and organ function. |date=04.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24729935 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966668 }} * {{medline-title |title=[[PLA2R1]]: expression and function in cancer. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24667060 |full-text-url=https://sci-hub.do/10.1016/j.bbcan.2014.03.003 }} * {{medline-title |title=Senescence-secreted factors activate Myc and sensitize pretransformed cells to TRAIL-induced apoptosis. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24589226 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326894 }} * {{medline-title |title=Passage-dependent cancerous transformation of human mesenchymal stem cells under carcinogenic hypoxia. |date=07.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23568779 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688746 }} ==STS== * {{medline-title |title=Delayed Impairment of Postural, Physical, and Muscular Functions Following Downhill Compared to Level Walking in Older People. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33192547 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609421 }} * {{medline-title |title=Novel Resistance Training Approach to Monitoring the Volume in Older Adults: The Role of Movement Velocity. |date=17.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33080817 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589697 }} * {{medline-title |title=Autophagy displays divergent roles during intermittent amino acid starvation and toxic stress-induced senescence in cultured skeletal muscle cells. |date=06.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33022071 |full-text-url=https://sci-hub.do/10.1002/jcp.30079 }} * {{medline-title |title=Sodium tanshinone IIA sulfonate restrains fibrogenesis through induction of senescence in mice with induced deep endometriosis. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32651107 |full-text-url=https://sci-hub.do/10.1016/j.rbmo.2020.04.006 }} * {{medline-title |title=The WRKY53 transcription factor enhances stilbene synthesis and disease resistance by interacting with MYB14 and MYB15 in Chinese wild grape. |date=30.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32080737 |full-text-url=https://sci-hub.do/10.1093/jxb/eraa097 }} * {{medline-title |title=On the role of ageing and musculoskeletal pain on dynamic balance in manual workers. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31733466 |full-text-url=https://sci-hub.do/10.1016/j.jelekin.2019.102374 }} * {{medline-title |title=The Copenhagen Sarcopenia Study: lean mass, strength, power, and physical function in a Danish cohort aged 20-93 years. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31419087 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6903448 }} * {{medline-title |title=30-day mortality in frail patients undergoing cardiac surgery: the results of the [i]frailty in cardiac surgery (FICS) copenhagen study[/i]. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31304801 |full-text-url=https://sci-hub.do/10.1080/14017431.2019.1644366 }} * {{medline-title |title=Chronic Fish Oil Consumption with Resistance Training Improves Grip Strength, Physical Function, and Blood Pressure in Community-Dwelling Older Adults. |date=09.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31323951 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680896 }} * {{medline-title |title=Effects of Tai Chi versus Taekkyon on balance, lower-extremity strength, and gait ability in community-dwelling older women: A single-blinded randomized clinical trial. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31282402 |full-text-url=https://sci-hub.do/10.3233/BMR-181493 }} * {{medline-title |title=Short-term starvation stress at young adult stages enhances meiotic activity of germ cells to maintain spermatogenesis in aged male Caenorhabditis elegans. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30816005 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516166 }} * {{medline-title |title=Flexibility in joint coordination remains unaffected by force and balance demands in young and old adults during simple sit-to-stand tasks. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30474739 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373350 }} * {{medline-title |title=The influence of knee extensor fatigue on lower extremity muscle activity during chair rise in young and older adults. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30317389 |full-text-url=https://sci-hub.do/10.1007/s00421-018-3999-4 }} * {{medline-title |title=The sit-to-stand muscle power test: An easy, inexpensive and portable procedure to assess muscle power in older people. |date=02.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30179662 |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.08.006 }} * {{medline-title |title=Visual-Vestibular Interaction for Postural Control During Sit-to-Stand: Effects of Aging. |date=01.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30008245 |full-text-url=https://sci-hub.do/10.1123/mc.2017-0045 }} * {{medline-title |title=From Intervention to Co-constitution: New Directions in Theorizing about Aging and Technology. |date=09.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29850812 |full-text-url=https://sci-hub.do/10.1093/geront/gny050 }} * {{medline-title |title=Age-related Changes in Postural Sway During Sit-to-stand in Typical Children and Children with Cerebral Palsy. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29621425 |full-text-url=https://sci-hub.do/10.1080/00222895.2018.1454396 }} * {{medline-title |title=Ectopic expression of Vp[[STS]]29, a stilbene synthase gene from Vitis pseudoreticulata, indicates [[STS]] presence in cytosolic oil bodies. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29589146 |full-text-url=https://sci-hub.do/10.1007/s00425-018-2883-0 }} * {{medline-title |title=Short-Term Training and Detraining Effects of Supervised vs. Unsupervised Resistance Exercise in Aging Adults. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29528961 |full-text-url=https://sci-hub.do/10.1519/JSC.0000000000002536 }} * {{medline-title |title=The coordination of joint movements during sit-to-stand motion in old adults: the uncontrolled manifold analysis. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29333362 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743431 }} * {{medline-title |title=The role of thigh muscular efforts in limiting sit-to-stand capacity in healthy young and older adults. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28238153 |full-text-url=https://sci-hub.do/10.1007/s40520-016-0702-7 }} * {{medline-title |title=Hippocampal structure predicts cortical indices of reactivation of related items. |date=27.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27939369 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266601 }} * {{medline-title |title=Aortic Valve Replacement With or Without Concurrent Coronary Artery Bypass Grafting in Octogenarians: Eight-Year Cohort Study. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27432737 |full-text-url=https://sci-hub.do/10.1016/j.hlc.2016.04.028 }} * {{medline-title |title=Anatomical cross-sectional area of the quadriceps femoris and sit-to-stand test score in middle-aged and elderly population: development of a predictive equation. |date=29.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27405228 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940975 }} * {{medline-title |title=Association between Physical Fitness and Successful Aging in Taiwanese Older Adults. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26963614 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786127 }} * {{medline-title |title=Is this [[STS]] work-related? ISO 1999 predictions as an adjunct to clinical judgment. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26443047 |full-text-url=https://sci-hub.do/10.1002/ajim.22534 }} * {{medline-title |title=Effects of Strength Training Using Unstable Surfaces on Strength, Power and Balance Performance Across the Lifespan: A Systematic Review and Meta-analysis. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26359066 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656700 }} * {{medline-title |title=Lean Body Mass Associated with Upper Body Strength in Healthy Older Adults While Higher Body Fat Limits Lower Extremity Performance and Endurance. |date=26.08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26343709 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586522 }} * {{medline-title |title=Psychometric properties of the Swedish version of the Self-Transcendence Scale among very old people. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25985498 |full-text-url=https://sci-hub.do/10.1891/1061-3749.23.1.96 }} * {{medline-title |title=Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25765287 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475460 }} * {{medline-title |title=Kinematic analysis of motor strategies in frail aged adults during the Timed Up and Go: how to spot the motor frailty? |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25759570 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345997 }} * {{medline-title |title=Sit-to-stand test: Performance and determinants across the age-span. |date=2010 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25598584 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293702 }} * {{medline-title |title=Developing a measure of muscular power during a functional task for older adults. |date=30.12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25551186 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290456 }} * {{medline-title |title=Behavior and neural correlates of empathy in adolescents. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24993549 |full-text-url=https://sci-hub.do/10.1159/000363318 }} * {{medline-title |title=Can sit-to-stand lower limb muscle power predict fall status? |date=07.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24974126 |full-text-url=https://sci-hub.do/10.1016/j.gaitpost.2014.05.064 }} * {{medline-title |title=Physical working capacity at fatigue threshold (PWCFT) is associated with sarcopenia-related body composition and measures of functionality in older adults. |date=09-10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24856645 |full-text-url=https://sci-hub.do/10.1016/j.archger.2014.04.012 }} * {{medline-title |title=Expression of an AtNAP gene homolog in senescing morning glory (Ipomoea nil) petals of two cultivars with a different flower life span. |date=01.05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24709156 |full-text-url=https://sci-hub.do/10.1016/j.jplph.2014.01.008 }} * {{medline-title |title=Region of stability derived by center of mass acceleration better identifies individuals with difficulty in sit-to-stand movement. |date=04.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24259008 |full-text-url=https://sci-hub.do/10.1007/s10439-013-0945-9 }} ==CD38== * {{medline-title |title=Re-equilibration of imbalanced NAD metabolism ameliorates the impact of telomere dysfunction. |date=02.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32935380 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604620 }} * {{medline-title |title=Macrophage Immunometabolism and Inflammaging: Roles of Mitochondrial Dysfunction, Cellular Senescence, [[CD38]], and NAD. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32774895 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409778 }} * {{medline-title |title=TNFRSF12A and [[CD38]] Contribute to a Vicious Circle for Chronic Obstructive Pulmonary Disease by Engaging Senescence Pathways. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32537452 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268922 }} * {{medline-title |title=Aging alters acetylation status in skeletal and cardiac muscles. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32300965 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286993 }} * {{medline-title |title=[[CD38]] in Neurodegeneration and Neuroinflammation. |date=18.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32085567 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072759 }} * {{medline-title |title=[[CD38]], a Receptor with Multifunctional Activities: From Modulatory Functions on Regulatory Cell Subsets and Extracellular Vesicles, to a Target for Therapeutic Strategies. |date=27.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31783629 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953043 }} * {{medline-title |title=Age-related alterations in human gut [[CD4]] T cell phenotype, T helper cell frequencies, and functional responses to enteric bacteria. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31573727 |full-text-url=https://sci-hub.do/10.1002/JLB.5A0919-177RR }} * {{medline-title |title=[[CD38]] Deficiency Alleviates D-Galactose-Induced Myocardial Cell Senescence Through NAD /Sirt1 Signaling Pathway. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31551807 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735286 }} * {{medline-title |title=Metabolism and biochemical properties of nicotinamide adenine dinucleotide (NAD) analogs, nicotinamide guanine dinucleotide (NGD) and nicotinamide hypoxanthine dinucleotide (NHD). |date=11.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31511627 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739475 }} * {{medline-title |title=The Multi-faceted Ecto-enzyme [[CD38]]: Roles in Immunomodulation, Cancer, Aging, and Metabolic Diseases. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31214171 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555258 }} * {{medline-title |title=Interacting NAD and Cell Senescence Pathways Complicate Antiaging Therapies. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31140365 |full-text-url=https://sci-hub.do/10.1089/rej.2019.2218 }} * {{medline-title |title=The NADase [[CD38]] is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD decline. |date=28.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975470 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486859 }} * {{medline-title |title=Measuring [[CD38]] Hydrolase and Cyclase Activities: 1,N -Ethenonicotinamide Adenine Dinucleotide (ε-NAD) and Nicotinamide Guanine Dinucleotide (NGD) Fluorescence-based Methods. |date=20.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30112426 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089541 }} * {{medline-title |title=The Plasma NAD Metabolome Is Dysregulated in "Normal" Aging. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30124109 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482912 }} * {{medline-title |title=Assays for NAD -Dependent Reactions and NAD Metabolites. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097862 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409209 }} * {{medline-title |title=Decreased NAD Activates [[STAT3]] and Integrin Pathways to Drive Epithelial-Mesenchymal Transition. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29980616 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166677 }} * {{medline-title |title=Innate and adaptive immune dysregulation in critically ill ICU patients. |date=05.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29976949 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033948 }} * {{medline-title |title=Abnormalities of age-related T cell senescence in Parkinson's disease. |date=28.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29807534 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972443 }} * {{medline-title |title=A Potent and Specific [[CD38]] Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD Decline. |date=01.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29719225 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935140 }} * {{medline-title |title=Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes. |date=10.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29634344 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277084 }} * {{medline-title |title=Hyper-Expression of PD-1 Is Associated with the Levels of Exhausted and Dysfunctional Phenotypes of Circulating CD161 TCR iVα7.2 Mucosal-Associated Invariant T Cells in Chronic Hepatitis B Virus Infection. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29616020 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868455 }} * {{medline-title |title=The Pharmacology of [[CD38]]/NADase: An Emerging Target in Cancer and Diseases of Aging. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482842 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885288 }} * {{medline-title |title=NAD Deficiency Is a Common Central Pathological Factor of a Number of Diseases and Aging: Mechanisms and Therapeutic Implications. |date=20.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29295624 |full-text-url=https://sci-hub.do/10.1089/ars.2017.7445 }} * {{medline-title |title=Reevaluation of immune activation in the era of cART and an aging HIV-infected population. |date=19.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29046481 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846952 }} * {{medline-title |title=Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses. |date=17.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28817118 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596542 }} * {{medline-title |title=Age dependent differences in the kinetics of γδ T cells after influenza vaccination. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28700738 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507438 }} * {{medline-title |title=NAD and the aging process: Role in life, death and everything in between. |date=05.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27825999 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419884 }} * {{medline-title |title=Constitutive Expression of Inducible Cyclic Adenosine Monophosphate Early Repressor (ICER) in Cycling Quiescent Hematopoietic Cells: Implications for Aging Hematopoietic Stem Cells. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27822872 |full-text-url=https://sci-hub.do/10.1007/s12015-016-9701-5 }} * {{medline-title |title=Why NAD( ) Declines during Aging: It's Destroyed. |date=14.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27304496 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088772 }} * {{medline-title |title=[[CD38]] Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an [[SIRT3]]-Dependent Mechanism. |date=14.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27304511 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911708 }} * {{medline-title |title=Immunity in young adult survivors of childhood leukemia is similar to the elderly rather than age-matched controls: Role of cytomegalovirus. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27129782 |full-text-url=https://sci-hub.do/10.1002/eji.201646356 }} * {{medline-title |title=Aging of immune system: Immune signature from peripheral blood lymphocyte subsets in 1068 healthy adults. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26886066 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931839 }} * {{medline-title |title=Peripheral loss of CD8( ) CD161( ) TCRVα7·2( ) mucosal-associated invariant T cells in chronic hepatitis C virus-infected patients. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26681320 |full-text-url=https://sci-hub.do/10.1111/eci.12581 }} * {{medline-title |title=Probiotics Reduce Inflammation in Antiretroviral Treated, HIV-Infected Individuals: Results of the "Probio-HIV" Clinical Trial. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26376436 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573418 }} * {{medline-title |title=Concurrent loss of co-stimulatory molecules and functional cytokine secretion attributes leads to proliferative senescence of CD8( ) T cells in HIV/TB co-infection. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26071876 |full-text-url=https://sci-hub.do/10.1016/j.cellimm.2015.05.005 }} * {{medline-title |title=Mapping NAD( ) metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence. |date=04.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24337988 |full-text-url=https://sci-hub.do/10.1007/s10522-013-9489-5 }} * {{medline-title |title=Accelerated aging in HIV/AIDS: novel biomarkers of senescent human CD8 T cells. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23717651 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661524 }} ==CDK4== * {{medline-title |title=Emerging Roles for the [i]INK4a/ARF[/i] ([i]CDKN2A[/i]) Locus in Adipose Tissue: Implications for Obesity and Type 2 Diabetes. |date=22.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32971832 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563355 }} * {{medline-title |title=Guilu Erxian Glue () Inhibits Chemotherapy-Induced Bone Marrow Hematopoietic Stem Cell Senescence in Mice May via p16 -Rb Signaling Pathway. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32915425 |full-text-url=https://sci-hub.do/10.1007/s11655-020-3098-3 }} * {{medline-title |title=Hepatoprotective effects of hydroxysafflor yellow A in D-galactose-treated aging mice. |date=15.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32454116 |full-text-url=https://sci-hub.do/10.1016/j.ejphar.2020.173214 }} * {{medline-title |title=Astragaloside IV ameliorates radiation-induced senescence via antioxidative mechanism. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32412100 |full-text-url=https://sci-hub.do/10.1111/jphp.13284 }} * {{medline-title |title=Expression of p16 in nodular fasciitis: an implication for self-limited and inflammatory nature of the lesion. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31933915 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945175 }} * {{medline-title |title=Anti-cell growth and anti-cancer stem cell activity of the [[CDK4]]/6 inhibitor palbociclib in breast cancer cells. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31823286 |full-text-url=https://sci-hub.do/10.1007/s12282-019-01035-5 }} * {{medline-title |title=Compromising the constitutive p16 expression sensitizes human neuroblastoma cells to Hsp90 inhibition and promotes premature senescence. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31692039 |full-text-url=https://sci-hub.do/10.1002/jcb.29493 }} * {{medline-title |title=Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential. |date=22.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31112603 |full-text-url=https://sci-hub.do/10.1093/gerona/glz077 }} * {{medline-title |title=Ribosomal protein RPL22/eL22 regulates the cell cycle by acting as an inhibitor of the [[CDK4]]-cyclin D complex. |date=03-04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30874462 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464582 }} * {{medline-title |title=p16 deletion in cells of the intervertebral disc affects their matrix homeostasis and senescence associated secretory phenotype without altering onset of senescence. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30811968 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708504 }} * {{medline-title |title=Efficient immortalization of cells derived from critically endangered Tsushima leopard cat (Prionailurus bengalensis euptilurus) with expression of mutant [[CDK4]], Cyclin D1, and telomerase reverse transcriptase. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225752 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269356 }} * {{medline-title |title=Effects of Fibronectin 1 on Cell Proliferation, Senescence and Apoptosis of Human Glioma Cells Through the PI3K/AKT Signaling Pathway. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048971 |full-text-url=https://sci-hub.do/10.1159/000492096 }} * {{medline-title |title=Cyclin D1 depletion interferes with oxidative balance and promotes cancer cell senescence. |date=25.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29880532 |full-text-url=https://sci-hub.do/10.1242/jcs.214726 }} * {{medline-title |title=Fucoidan Rescues p-Cresol-Induced Cellular Senescence in Mesenchymal Stem Cells via FAK-Akt-TWIST Axis. |date=06.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29642406 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923408 }} * {{medline-title |title=Carvacrol nanoemulsion evokes cell cycle arrest, apoptosis induction and autophagy inhibition in doxorubicin resistant-A549 cell line. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29405784 |full-text-url=https://sci-hub.do/10.1080/21691401.2018.1434187 }} * {{medline-title |title=Mechanistic understanding of the role of [[ATRX]] in senescence provides new insight for combinatorial therapies with [[CDK4]] inhibitors. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29404388 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791849 }} * {{medline-title |title=Glutaredoxin-1 Silencing Induces Cell Senescence via p53/p21/p16 Signaling Axis. |date=02.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29356545 |full-text-url=https://sci-hub.do/10.1021/acs.jproteome.7b00761 }} * {{medline-title |title=Inhibition of [[CIP2A]] attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma. |date=08.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175329 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.11.124 }} * {{medline-title |title=Preclinical characterization of abemaciclib in hormone receptor positive breast cancer. |date=19.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29050219 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642494 }} * {{medline-title |title=Immortalized prairie vole-derived fibroblasts (VMF-K4DTs) can be transformed into pluripotent stem cells and provide a useful tool with which to determine optimal reprogramming conditions. |date=21.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28331164 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481634 }} * {{medline-title |title=Molecular mechanism of G arrest and cellular senescence induced by LEE011, a novel [[CDK4]]/CDK6 inhibitor, in leukemia cells. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28286417 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340031 }} * {{medline-title |title=p16 loss rescues functional decline of Brca1-deficient mammary stem cells. |date=18.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28278054 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405722 }} * {{medline-title |title=p16 enhances the transcriptional and the apoptotic functions of p53 through DNA-dependent interaction. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28218424 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266037 }} * {{medline-title |title=p16INK4a suppresses [[BRCA1]]-deficient mammary tumorigenesis. |date=20.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27811360 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356676 }} * {{medline-title |title=A steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1. |date=27.09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27542238 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325331 }} * {{medline-title |title=[[CDK4]]-[[CDK6]] inhibitors induce autophagy-mediated degradation of [[DNMT1]] and facilitate the senescence antitumor response. |date=02.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27532423 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079664 }} * {{medline-title |title=Sperm-associated antigen 9 ([[SPAG9]]) promotes the survival and tumor growth of triple-negative breast cancer cells. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27449044 |full-text-url=https://sci-hub.do/10.1007/s13277-016-5240-6 }} * {{medline-title |title=Double staining of β-galactosidase with fibrosis and cancer markers reveals the chronological appearance of senescence in liver carcinogenesis induced by diethylnitrosamine. |date=22.01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26589970 |full-text-url=https://sci-hub.do/10.1016/j.toxlet.2015.11.011 }} * {{medline-title |title=Efficacy of [[CDK4]] inhibition against sarcomas depends on their levels of [[CDK4]] and p16ink4 mRNA. |date=01.12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26528855 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747352 }} * {{medline-title |title=Suppression of [[RAD21]] Induces Senescence of MDA-[[MB]]-231 Human Breast Cancer Cells Through [[RB1]] Pathway Activation Via c-Myc Downregulation. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26529363 |full-text-url=https://sci-hub.do/10.1002/jcb.25426 }} * {{medline-title |title=Molecular differences between stromal cell populations from deciduous and permanent human teeth. |date=18.04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25927523 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417277 }} * {{medline-title |title=Functional Effect of Pim1 Depends upon Intracellular Localization in Human Cardiac Progenitor Cells. |date=29.05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25882843 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447967 }} * {{medline-title |title=[[MDM2]] turnover and expression of [[ATRX]] determine the choice between quiescence and senescence in response to [[CDK4]] inhibition. |date=10.04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25803170 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480747 }} * {{medline-title |title=Evidence for a [[CDK4]]-dependent checkpoint in a conditional model of cellular senescence. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25695870 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613988 }} * {{medline-title |title=MiR-506 suppresses proliferation and induces senescence by directly targeting the [[CDK4]]/6-[[FOXM1]] axis in ovarian cancer. |date=07.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24604117 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144705 }} * {{medline-title |title=Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes. |date=15.08.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23707792 |full-text-url=https://sci-hub.do/10.1016/j.mce.2013.05.003 }} * {{medline-title |title=Oxidized low-density lipoprotein induces hematopoietic stem cell senescence. |date=09.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23620010 |full-text-url=https://sci-hub.do/10.1002/cbin.10121 }} ==EGFR== * {{medline-title |title=Type I Collagen Aging Increases Expression and Activation of [[EGFR]] and Induces Resistance to Erlotinib in Lung Carcinoma in 3D Matrix Model. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33014812 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511549 }} * {{medline-title |title=Catalog of Lung Cancer Gene Mutations Among Chinese Patients. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850378 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417348 }} * {{medline-title |title=Activation of epidermal growth factor receptor signaling mediates cellular senescence induced by certain pro-inflammatory cytokines. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32323422 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253070 }} * {{medline-title |title=Comparative effectiveness and cost-effectiveness of three first-line [[EGFR]]-tyrosine kinase inhibitors: Analysis of real-world data in a tertiary hospital in Taiwan. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32267879 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141611 }} * {{medline-title |title=An Optogenetic Method to Study Signal Transduction in Intestinal Stem Cell Homeostasis. |date=01.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32201167 |full-text-url=https://sci-hub.do/10.1016/j.jmb.2020.03.019 }} * {{medline-title |title=Different cellular properties and loss of nuclear signalling of porcine epidermal growth factor receptor with aging. |date=01.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32001323 |full-text-url=https://sci-hub.do/10.1016/j.ygcen.2020.113415 }} * {{medline-title |title=Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway. |date=13.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31935369 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146079 }} * {{medline-title |title=Association between [[EGFR]] mutation and ageing, history of pneumonia and gastroesophageal reflux disease among patients with advanced lung cancer. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31634646 |full-text-url=https://sci-hub.do/10.1016/j.ejca.2019.09.010 }} * {{medline-title |title=Targeting amphiregulin ([[AREG]]) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31493351 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826133 }} * {{medline-title |title=Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms. |date=22.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31332237 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646318 }} * {{medline-title |title=The role of [[EGFR]] signaling in age-related osteoporosis in mouse cortical bone. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298955 |full-text-url=https://sci-hub.do/10.1096/fj.201900436RR }} * {{medline-title |title=Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes. |date=13.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31200451 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627600 }} * {{medline-title |title=[[EGF]]/[[EGF]]R upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence. |date=04.12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30514230 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280426 }} * {{medline-title |title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574 |full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2 }} * {{medline-title |title=Quantum Modeling: A Bridge between the Pumping and Signaling Functions of Na/K-ATPase. |date=09.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30096926 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121303 }} * {{medline-title |title=Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer. |date=30.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29682186 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908287 }} * {{medline-title |title=Withanolide A extends the lifespan in human [[EGFR]]-driven cancerous Caenorhabditis elegans. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29427754 |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.02.004 }} * {{medline-title |title=30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Nongenomic effects via the mineralocorticoid receptor. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28348113 |full-text-url=https://sci-hub.do/10.1530/JOE-16-0659 }} * {{medline-title |title=Inverse relationship between Alzheimer's disease and cancer, and other factors contributing to Alzheimer's disease: a systematic review. |date=22.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27875990 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120447 }} * {{medline-title |title=Low-frequency [i]KRAS[/i] mutations are prevalent in lung adenocarcinomas. |date=03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27795727 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084916 }} * {{medline-title |title=Association of Polymorphisms in Connective Tissue Growth Factor and Epidermal Growth Factor Receptor Genes With Human Longevity. |date=01.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27365368 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861942 }} * {{medline-title |title=sPLA2 -IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induces Differentiation Mediated Through Enhanced JNK/c-Jun Activation. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27299855 |full-text-url=https://sci-hub.do/10.1002/stem.2418 }} * {{medline-title |title=Mechanisms of skin aging induced by [[EGFR]] inhibitors. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27165055 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611667 }} * {{medline-title |title=Prolactin, [[EGFR]], vimentin and α-actin profiles in elderly rat prostate subjected to steroid hormonal imbalance. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27021728 |full-text-url=https://sci-hub.do/10.1016/j.tice.2016.03.008 }} * {{medline-title |title=Loss of Maspardin Attenuates the Growth and Maturation of Mouse Cortical Neurons. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26978163 |full-text-url=https://sci-hub.do/10.1159/000443666 }} * {{medline-title |title=Expression profile analysis of new candidate genes for the therapy of primary osteoporosis. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26914116 }} * {{medline-title |title=Selective coexpression of V[[EGF]] receptor 2 in [[EGF]]RvIII-positive glioblastoma cells prevents cellular senescence and contributes to their aggressive nature. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26420897 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827039 }} * {{medline-title |title=Bradykinin inhibits oxidative stress-induced senescence of endothelial progenitor cells through the B2R/AKT/RB and B2R/[[EGFR]]/RB signal pathways. |date=22.09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26360782 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694787 }} * {{medline-title |title=First-line gefitinib treatment in elderly patients (aged ≥75 years) with non-small cell lung cancer harboring [[EGFR]] mutations. |date=10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26254024 |full-text-url=https://sci-hub.do/10.1007/s00280-015-2841-5 }} * {{medline-title |title=Increased centrosome amplification in aged stem cells of the Drosophila midgut. |date=25.07.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24971546 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2014.06.085 }} * {{medline-title |title=Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain. |date=07.05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24843006 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038845 }} * {{medline-title |title=Thiamin concentration in geriatric hospitalized patients using frusemide. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24597996 |full-text-url=https://sci-hub.do/10.1080/21551197.2013.875501 }} * {{medline-title |title=4-Hydroxynonenal impairs transforming growth factor-β1-induced elastin synthesis via epidermal growth factor receptor activation in human and murine fibroblasts. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24561579 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2014.02.015 }} * {{medline-title |title=Cellular senescence or [[EGF]]R signaling induces Interleukin 6 (IL-6) receptor expression controlled by mammalian target of rapamycin (mTOR). |date=01.11.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24047696 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895430 }} * {{medline-title |title=Clinical significance of proliferation, apoptosis and senescence of nasopharyngeal cells by the simultaneously blocking [[EGF]], IGF-1 receptors and Bcl-xl genes. |date=01.11.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24055032 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2013.08.070 }} * {{medline-title |title=[[EGFR]] inhibitor erlotinib delays disease progression but does not extend survival in the [[SOD1]] mouse model of ALS. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23638043 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637182 }} * {{medline-title |title=Gene-guided gefitinib switch maintenance therapy for patients with advanced [[EGFR]] mutation-positive non-small cell lung cancer: an economic analysis. |date=29.01.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23360224 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568065 }} ==BACE1== * {{medline-title |title=Electric Stimulation of Neurogenesis Improves Behavioral Recovery After Focal Ischemia in Aged Rats. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32742258 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365235 }} * {{medline-title |title=Dendrobium nobile Lindl. Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32538851 |full-text-url=https://sci-hub.do/10.3233/JAD-200308 }} * {{medline-title |title=Disruption of synaptic expression pattern and age-related DNA oxidation in a neuronal model of lead-induced toxicity. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32058320 |full-text-url=https://sci-hub.do/10.1016/j.etap.2020.103350 }} * {{medline-title |title=Age- and sex-dependent profiles of [[APP]] fragments and key secretases align with changes in despair-like behavior and cognition in young [[APP]]Swe/Ind mice. |date=02.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30803762 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.02.083 }} * {{medline-title |title=Selective reduction of [[APP]]-[[BACE1]] activity improves memory via NMDA-NR2B receptor-mediated mechanisms in aged PD[[APP]] mice. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30572184 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357873 }} * {{medline-title |title=Temporal Effects of Neuron-specific beta-secretase 1 ([[BACE1]]) Knock-in on the Mouse Brain Metabolome: Implications for Alzheimer's Disease. |date=15.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30496823 |full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2018.11.031 }} * {{medline-title |title=Removal of p75 Neurotrophin Receptor Expression from Cholinergic Basal Forebrain Neurons Reduces Amyloid-β Plaque Deposition and Cognitive Impairment in Aged APP/PS1 Mice. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30374941 |full-text-url=https://sci-hub.do/10.1007/s12035-018-1404-2 }} * {{medline-title |title=Axonal organization defects in the hippocampus of adult conditional [[BACE1]] knockout mice. |date=19.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30232227 |full-text-url=https://sci-hub.do/10.1126/scitranslmed.aao5620 }} * {{medline-title |title=Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: Implications for Alzheimer disease. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29981845 |full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.07.005 }} * {{medline-title |title=Effects of senescence and angiotensin II on expression and processing of amyloid precursor protein in human cerebral microvascular endothelial cells. |date=15.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29348391 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811245 }} * {{medline-title |title=Neuroprotective potential of high-dose biotin. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29150274 |full-text-url=https://sci-hub.do/10.1016/j.mehy.2017.10.012 }} * {{medline-title |title=The pathological roles of [[NDRG2]] in Alzheimer's disease, a study using animal models and APPwt-overexpressed cells. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28670853 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492714 }} * {{medline-title |title=Ferulic Acid Suppresses Amyloid [i]β[/i] Production in the Human Lens Epithelial Cell Stimulated with Hydrogen Peroxide. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28409157 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376927 }} * {{medline-title |title=Vitamin D Combined with Resveratrol Prevents Cognitive Decline in SAMP8 Mice. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28176624 |full-text-url=https://sci-hub.do/10.2174/1567205014666170207093455 }} * {{medline-title |title=Prevention of tau increase in cerebrospinal fluid of [[APP]] transgenic mice suggests downstream effect of [[BACE1]] inhibition. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27750032 |full-text-url=https://sci-hub.do/10.1016/j.jalz.2016.09.005 }} * {{medline-title |title=Fuzhisan Ameliorates the Memory Deficits in Aged SAMP8 Mice via Decreasing Aβ Production and Tau Hyperphosphorylation of the Hippocampus. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27518086 |full-text-url=https://sci-hub.do/10.1007/s11064-016-2028-4 }} * {{medline-title |title=Behaviour and cognitive changes correlated with hippocampal neuroinflammaging and neuronal markers in female SAMP8, a model of accelerated senescence. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27094468 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.03.014 }} * {{medline-title |title=Partial [[BACE1]] reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of [[APP]]-CTF. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26923405 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773919 }} * {{medline-title |title=miR-186 is decreased in aged brain and suppresses [[BACE1]] expression. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26710318 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837067 }} * {{medline-title |title=IL-17A is implicated in lipopolysaccharide-induced neuroinflammation and cognitive impairment in aged rats via microglial activation. |date=15.09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26373740 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572693 }} * {{medline-title |title=Functions of miR-9 and miR-9* during Aging in SAMP8 Mice and Their Possible Mechanisms. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26149132 |full-text-url=https://sci-hub.do/10.3881/j.issn.1000-503X.2015.03.001 }} * {{medline-title |title=[[SNX15]] Regulates Cell Surface Recycling of [[APP]] and Aβ Generation. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26115702 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691577 }} * {{medline-title |title=Non-neuronal and neuronal [[BACE1]] elevation in association with angiopathic and leptomeningeal β-amyloid deposition in the human brain. |date=02.05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25934480 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428107 }} * {{medline-title |title=The flavonoid quercetin ameliorates Alzheimer's disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer's disease model mice. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25666032 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387064 }} * {{medline-title |title=Elevation of brain magnesium prevents synaptic loss and reverses cognitive deficits in Alzheimer's disease mouse model. |date=13.09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25213836 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172865 }} * {{medline-title |title=Development and characterization of an aged onset model of Alzheimer's disease in Drosophila melanogaster. |date=11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25173219 |full-text-url=https://sci-hub.do/10.1016/j.expneurol.2014.08.021 }} * {{medline-title |title=Sildenafil Decreases [[BACE1]] and Cathepsin B Levels and Reduces APP Amyloidogenic Processing in the SAMP8 Mouse. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25063079 |full-text-url=https://sci-hub.do/10.1093/gerona/glu106 }} * {{medline-title |title=Oxidized LDL lipids increase β-amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation. |date=10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25048970 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180009 }} * {{medline-title |title=Increased mtDNA mutations with aging promotes amyloid accumulation and brain atrophy in the [[APP]]/Ld transgenic mouse model of Alzheimer's disease. |date=02.05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24885175 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028006 }} * {{medline-title |title=Lessons from a [[BACE1]] inhibitor trial: off-site but not off base. |date=10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24530026 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205206 }} * {{medline-title |title=Expression of amyloid-associated miRNAs in both the forebrain cortex and hippocampus of middle-aged rat. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24401368 |full-text-url=https://sci-hub.do/10.1159/000356646 }} * {{medline-title |title=MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 ([[BACE1]]) in human primary brain cultures and is reduced in brain tissue specimens of Alzheimer disease subjects. |date=21.02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24352696 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931075 }} * {{medline-title |title=Rheb GTPase regulates β-secretase levels and amyloid β generation. |date=28.02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24368770 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937651 }} * {{medline-title |title=Can [[BACE1]] inhibition mitigate early axonal pathology in neurological diseases? |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24081378 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995167 }} * {{medline-title |title=Stress contributes to the development of central insulin resistance during aging: implications for Alzheimer's disease. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24090692 |full-text-url=https://sci-hub.do/10.1016/j.bbadis.2013.09.013 }} * {{medline-title |title=[Effect of PNS on the activity and content of [[BACE1]] in the brain of SAMP8 mice with Alzheimer's disease]. |date=07.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24063218 }} ==LBP== * {{medline-title |title=Age-Related Colonic Mucosal Microbiome Community Shifts in Monkeys. |date=06.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33021628 |full-text-url=https://sci-hub.do/10.1093/gerona/glaa256 }} * {{medline-title |title=Lipopolysaccharide binding protein is associated with CVD risk in older adults. |date=08.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32895891 |full-text-url=https://sci-hub.do/10.1007/s40520-020-01684-z }} * {{medline-title |title=Influence of Frailty Status on Pain, Disability, and Quality of Life in Older Adults with Acute Low Back Pain: Results from the Back Complaints in the Elders (BACE-Brazil) Study. |date=14.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32792030 |full-text-url=https://sci-hub.do/10.1017/S0714980820000288 }} * {{medline-title |title=Aging-related liver degeneration is associated with increased bacterial endotoxin and lipopolysaccharide binding protein levels. |date=01.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32090603 |full-text-url=https://sci-hub.do/10.1152/ajpgi.00345.2018 }} * {{medline-title |title=Distal colonic transit is linked to gut microbiota diversity and microbial fermentation in humans with slow colonic transit. |date=01.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31869241 |full-text-url=https://sci-hub.do/10.1152/ajpgi.00283.2019 }} * {{medline-title |title=Biomarkers of leaky gut are related to inflammation and reduced physical function in older adults with cardiometabolic disease and mobility limitations. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31654268 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925090 }} * {{medline-title |title=Needle-shaped amyloid deposition in rat mammary gland: evidence of a novel amyloid fibril protein. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31615282 |full-text-url=https://sci-hub.do/10.1080/13506129.2019.1675623 }} * {{medline-title |title=Inflammatory mediators and the risk of falls among older women with acute low back pain: data from Back Complaints in the Elders (BACE)-Brazil. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31606818 |full-text-url=https://sci-hub.do/10.1007/s00586-019-06168-x }} * {{medline-title |title=Effects of Lycium barbarum Polysaccharides on Health and Aging of [i]C. elegans[/i] Depend on [i]daf-12/daf-16[/i]. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31583041 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754959 }} * {{medline-title |title=Structural characterization of life-extending Caenorhabditis elegans Lipid Binding Protein 8. |date=10.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292465 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620326 }} * {{medline-title |title=Lycium barbarum polysaccharides extend the mean lifespan of Drosophila melanogaster. |date=17.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31259337 |full-text-url=https://sci-hub.do/10.1039/c8fo01751d }} * {{medline-title |title=Height loss but not body composition is related to low back pain in community-dwelling elderlies: Shimane CoHRE study. |date=10.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31077175 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511157 }} * {{medline-title |title=Aging of mouse intervertebral disc and association with back pain. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30936040 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549718 }} * {{medline-title |title=A comparison of the mitochondrial proteome and lipidome in the mouse and long-lived Pipistrelle bats. |date=19.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30892277 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461166 }} * {{medline-title |title=Chen-Style Tai Chi for Individuals (Aged 50 Years Old or Above) with Chronic Non-Specific Low Back Pain: A Randomized Controlled Trial. |date=12.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30759778 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388249 }} * {{medline-title |title=Lysosomal Signaling Promotes Longevity by Adjusting Mitochondrial Activity. |date=11.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30713071 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613828 }} * {{medline-title |title=Factors associated with lumbar disc high-intensity zone (HIZ) on T2-weighted magnetic resonance image: a retrospective study of 3185 discs in 637 patients. |date=04.12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30514333 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280348 }} * {{medline-title |title=Urolithin A Inhibits the Catabolic Effect of TNFα on Nucleus Pulposus Cell and Alleviates Intervertebral Disc Degeneration [i]in vivo[/i]. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30283339 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157327 }} * {{medline-title |title=Use of trunk muscle training and neuromuscular electrical stimulation to reduce pain and disability in an older adult with chronic low back pain: A case report. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29617180 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179941 }} * {{medline-title |title=Endotoxemia is modulated by quantity and quality of dietary fat in older adults. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129737 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.006 }} * {{medline-title |title=Correlates of a Recent History of Disabling Low Back Pain in Community-dwelling Older Persons: The Pain in the Elderly (PAINEL) Study. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29077624 |full-text-url=https://sci-hub.do/10.1097/AJP.0000000000000564 }} * {{medline-title |title=The Effectiveness and Safety of Manual Therapy on Pain and Disability in Older Persons With Chronic Low Back Pain: A Systematic Review. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29079255 |full-text-url=https://sci-hub.do/10.1016/j.jmpt.2017.06.008 }} * {{medline-title |title=De-educate to re-educate: aging and low back pain. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28275956 |full-text-url=https://sci-hub.do/10.1007/s40520-017-0731-x }} * {{medline-title |title=Activity of Erector Spinae During Trunk Forward Bending and Backward Return: The Effects of Age. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28194659 |full-text-url=https://sci-hub.do/10.1007/s10439-017-1811-y }} * {{medline-title |title=Global Cysteine-Reactivity Profiling during Impaired Insulin/IGF-1 Signaling in C. elegans Identifies Uncharacterized Mediators of Longevity. |date=18.08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27499530 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003114 }} * {{medline-title |title=Age- and brain region-dependent α-synuclein oligomerization is attributed to alterations in intrinsic enzymes regulating α-synuclein phosphorylation in aging monkey brains. |date=23.02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27032368 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890980 }} * {{medline-title |title=Association of Lipopolysaccharide-Binding Protein With Aging-Related Adiposity Change and Prediabetes Among African Ancestry Men. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26721818 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764043 }} * {{medline-title |title=Age-related differences in trunk intrinsic stiffness. |date=11.04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26459489 |full-text-url=https://sci-hub.do/10.1016/j.jbiomech.2015.09.010 }} * {{medline-title |title=Probiotics Reduce Inflammation in Antiretroviral Treated, HIV-Infected Individuals: Results of the "Probio-HIV" Clinical Trial. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26376436 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573418 }} * {{medline-title |title=The effects of age and gender on the lumbopelvic rhythm in the sagittal plane in 309 subjects. |date=18.09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26294355 |full-text-url=https://sci-hub.do/10.1016/j.jbiomech.2015.07.030 }} * {{medline-title |title=Does physical activity moderate the relationship between depression symptomatology and low back pain? Cohort and co-twin control analyses nested in the longitudinal study of aging Danish twins (LSADT). |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26231337 |full-text-url=https://sci-hub.do/10.1007/s00586-015-4138-0 }} * {{medline-title |title=Aging. Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans. |date=02.01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25554789 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425353 }} * {{medline-title |title=Comparative study of human age estimation with or without preclassification of gender and facial expression. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25295308 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175379 }} * {{medline-title |title=Treatment of d-galactose induced mouse aging with Lycium barbarum polysaccharides and its mechanism study. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24146495 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794385 }} * {{medline-title |title=A study of Lycium barbarum polysaccharides ([[LBP]]) extraction technology and its anti-aging effect. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24146519 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794409 }} * {{medline-title |title=Paraspinal muscle morphology and composition: a 15-yr longitudinal magnetic resonance imaging study. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24091994 |full-text-url=https://sci-hub.do/10.1249/MSS.0000000000000179 }} ==DMD== * {{medline-title |title=Aldehyde dehydrogenases contribute to skeletal muscle homeostasis in healthy, aging, and Duchenne muscular dystrophy patients. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32157826 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432589 }} * {{medline-title |title=Life expectancy at birth in Duchenne muscular dystrophy: a systematic review and meta-analysis. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32107739 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387367 }} * {{medline-title |title=Control of Muscle Fibro-Adipogenic Progenitors by Myogenic Lineage is Altered in Aging and Duchenne Muscular Dystrophy. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31865646 |full-text-url=https://sci-hub.do/10.33594/000000196 }} * {{medline-title |title=Renal dysfunction can occur in advanced-stage Duchenne muscular dystrophy. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31725904 |full-text-url=https://sci-hub.do/10.1002/mus.26757 }} * {{medline-title |title=The long dystrophin gene product Dp427 modulates retinal function and vascular morphology in response to age and retinal ischemia. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31199961 |full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.104489 }} * {{medline-title |title=Hemojuvelin is a novel suppressor for Duchenne muscular dystrophy and age-related muscle wasting. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30884219 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596404 }} * {{medline-title |title=Age-dependent changes in metabolite profile and lipid saturation in dystrophic mice. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30848538 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777843 }} * {{medline-title |title=Muscle function and age are associated with loss of bone mineral density in Duchenne muscular dystrophy. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30623456 |full-text-url=https://sci-hub.do/10.1002/mus.26416 }} * {{medline-title |title=Use of bone age for evaluating bone density in patients with Duchenne muscular dystrophy: A preliminary report. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30636004 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417931 }} * {{medline-title |title=Age- and Expertise-Related Differences of Sensorimotor Network Dynamics during Force Control. |date=15.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048784 |full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2018.07.025 }} * {{medline-title |title=Mineralocorticoid Receptor Antagonists in Muscular Dystrophy Mice During Aging and Exercise. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30010143 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732783 }} * {{medline-title |title=Calcium current properties in dystrophin-deficient ventricular cardiomyocytes from aged mdx mice. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29333726 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789658 }} * {{medline-title |title=Immunoglobulin therapy ameliorates the phenotype and increases lifespan in the severely affected dystrophin-utrophin double knockout mice. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29255177 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865115 }} * {{medline-title |title=The experience of parents of adult sons with Duchenne muscular dystrophy regarding their prolonged roles as primary caregivers: a serial qualitative study. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172756 |full-text-url=https://sci-hub.do/10.1080/09638288.2017.1408148 }} * {{medline-title |title=Spatial and age-related changes in the microstructure of dystrophic and healthy diaphragms. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28877195 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587283 }} * {{medline-title |title=Growing patients with Duchenne muscular dystrophy: longitudinal changes in their dentofacial morphology and orofacial functional capacities. |date=06.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28520860 |full-text-url=https://sci-hub.do/10.1093/ejo/cjx038 }} * {{medline-title |title=Impaired regenerative capacity and lower revertant fibre expansion in dystrophin-deficient mdx muscles on DBA/2 background. |date=07.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27924830 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141435 }} * {{medline-title |title=Use of the six-minute walk test to characterize golden retriever muscular dystrophy. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27818009 |full-text-url=https://sci-hub.do/10.1016/j.nmd.2016.09.024 }} * {{medline-title |title=Small Fractions of Muscular Dystrophy Embryonic Stem Cells Yield Severe Cardiac and Skeletal Muscle Defects in Adult Mouse Chimeras. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27734557 |full-text-url=https://sci-hub.do/10.1002/stem.2518 }} * {{medline-title |title=Progressive muscle proteome changes in a clinically relevant pig model of Duchenne muscular dystrophy. |date=16.09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27634466 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025886 }} * {{medline-title |title=Dystrophin-Deficient Cardiomyopathy. |date=31.05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27230049 |full-text-url=https://sci-hub.do/10.1016/j.jacc.2016.02.081 }} * {{medline-title |title=Low Six4 and Six5 gene dosage improves dystrophic phenotype and prolongs life span of mdx mice. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27224259 |full-text-url=https://sci-hub.do/10.1111/dgd.12290 }} * {{medline-title |title=Molecular circuitry of stem cell fate in skeletal muscle regeneration, ageing and disease. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26956195 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918817 }} * {{medline-title |title=Crosstalk between RyR2 oxidation and phosphorylation contributes to cardiac dysfunction in mice with Duchenne muscular dystrophy. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26555638 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689641 }} * {{medline-title |title=Gastrocnemius medialis muscle architecture and physiological cross sectional area in adult males with Duchenne muscular dystrophy. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26032207 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133718 }} * {{medline-title |title=G-CSF supports long-term muscle regeneration in mouse models of muscular dystrophy. |date=13.04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25865621 |full-text-url=https://sci-hub.do/10.1038/ncomms7745 }} * {{medline-title |title=Lack of dystrophin protein Dp71 results in progressive cataract formation due to loss of fiber cell organization. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25489223 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225142 }} * {{medline-title |title=Age-dependent changes in diastolic Ca(2 ) and Na( ) concentrations in dystrophic cardiomyopathy: Role of Ca(2 ) entry and IP3. |date=03.10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25242522 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275309 }} * {{medline-title |title=Transitioning to adulthood with a progressive condition: best practice assumptions and individual experiences of young men with Duchenne muscular dystrophy. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25190331 |full-text-url=https://sci-hub.do/10.3109/09638288.2014.956187 }} * {{medline-title |title=Discovery of serum protein biomarkers in the mdx mouse model and cross-species comparison to Duchenne muscular dystrophy patients. |date=15.12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25027324 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240201 }} * {{medline-title |title=Notch signaling deficiency underlies age-dependent depletion of satellite cells in muscular dystrophy. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24906372 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107328 }} * {{medline-title |title=Evolution of life expectancy of patients with Duchenne muscular dystrophy at [[AFM]] Yolaine de Kepper centre between 1981 and 2011. |date=09.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23876223 |full-text-url=https://sci-hub.do/10.1016/j.rehab.2013.06.002 }} * {{medline-title |title=Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle. |date=01.11.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23784375 |full-text-url=https://sci-hub.do/10.1093/hmg/ddt287 }} * {{medline-title |title=Digestive capacity in weanling and mature horses. |date=05.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23463556 |full-text-url=https://sci-hub.do/10.2527/jas.2012-5789 }} * {{medline-title |title=Insights into skeletal muscle development and applications in regenerative medicine. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23273859 |full-text-url=https://sci-hub.do/10.1016/B978-0-12-405210-9.00002-3 }} ==FGF23== * {{medline-title |title=Phosphate as a Pathogen of Arteriosclerosis and Aging. |date=08.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33028781 |full-text-url=https://sci-hub.do/10.5551/jat.RV17045 }} * {{medline-title |title=Plasma Soluble αKlotho, Serum Fibroblast Growth Factor 23, and Mobility Disability in Community-Dwelling Older Adults. |date=01.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32405607 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209777 }} * {{medline-title |title=Astragalus improve aging bone marrow mesenchymal stem cells (BMSCs) vitality and osteogenesis through VD-[[FGF23]]-Klotho axis. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32355520 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191145 }} * {{medline-title |title=Protective effect of Polygonatum sibiricum Polysaccharide on D-galactose-induced aging rats model. |date=10.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32042011 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010663 }} * {{medline-title |title=[[FGF23]] expression is stimulated in transgenic α-Klotho longevity mouse model. |date=05.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31801907 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962016 }} * {{medline-title |title=Fibroblast growth factor 23 and symmetric dimethylarginine concentrations in geriatric cats. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31568615 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872607 }} * {{medline-title |title=Muscle-bone crosstalk and potential therapies for sarco-osteoporosis. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31106446 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331460 }} * {{medline-title |title=Extraskeletal Calcifications in Hutchinson-Gilford Progeria Syndrome. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31077852 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628204 }} * {{medline-title |title=Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages. |date=06.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30727969 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366057 }} * {{medline-title |title=Age-Related Changes and Effects of Bisphosphonates on Bone Turnover and Disease Progression in Fibrous Dysplasia of Bone. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30645769 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983318 }} * {{medline-title |title=Kotho and aging. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30557478 }} * {{medline-title |title=The Klotho proteins in health and disease. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30455427 |full-text-url=https://sci-hub.do/10.1038/s41581-018-0078-3 }} * {{medline-title |title=Wnt signaling in bone, kidney, intestine, and adipose tissue and interorgan interaction in aging. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30101565 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372353 }} * {{medline-title |title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357 |full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004 }} * {{medline-title |title=New Insights into the Mechanism of Action of Soluble Klotho. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29250031 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715364 }} * {{medline-title |title=The relevance of α-[[KL]]OTHO to the central nervous system: Some key questions. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28323064 |full-text-url=https://sci-hub.do/10.1016/j.arr.2017.03.003 }} * {{medline-title |title=Fibroblast Growth Factor 23 and the Risk of Infection-Related Hospitalization in Older Adults. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28122946 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373449 }} * {{medline-title |title=Reduction of calprotectin and phosphate during testosterone therapy in aging men: a randomized controlled trial. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28000180 |full-text-url=https://sci-hub.do/10.1007/s40618-016-0597-3 }} * {{medline-title |title=Association between circulating fibroblast growth factor-23 and age-related cardiovascular-renal parameters in a healthy Chinese population. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27427468 |full-text-url=https://sci-hub.do/10.1111/ggi.12844 }} * {{medline-title |title=The [[FGF23]]/[[KL]]OTHO Regulatory Network and Its Roles in Human Disorders. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27125741 |full-text-url=https://sci-hub.do/10.1016/bs.vh.2016.02.001 }} * {{medline-title |title=Wound healing delays in α-Klotho-deficient mice that have skin appearance similar to that in aged humans - Study of delayed wound healing mechanism. |date=13.05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27037022 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2016.03.138 }} * {{medline-title |title=Partial Reversal of Tissue Calcification and Extension of Life Span following Ammonium Nitrate Treatment of Klotho-Deficient Mice. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26881935 |full-text-url=https://sci-hub.do/10.1159/000443411 }} * {{medline-title |title=[Regulatory mechanism of circulating inorganic phosphate]. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26813498 |full-text-url=https://sci-hub.do/CliCa1602193198 }} * {{medline-title |title=Biological Role of Anti-aging Protein Klotho. |date=03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26528423 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608225 }} * {{medline-title |title=Soluble αKlotho as a candidate for the biomarker of aging. |date=27.11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26462468 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.10.018 }} * {{medline-title |title=Acetazolamide sensitive tissue calcification and aging of klotho-hypomorphic mice. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26307633 |full-text-url=https://sci-hub.do/10.1007/s00109-015-1331-x }} * {{medline-title |title=N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25860694 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393098 }} * {{medline-title |title=Intracellular signaling of the aging suppressor protein Klotho. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25601466 |full-text-url=https://sci-hub.do/10.2174/1566524015666150114111258 }} * {{medline-title |title=Tumour-associated osteomalacia and hypoglycaemia in a patient with prostate cancer: is Klotho involved? |date=17.11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25406200 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244358 }} * {{medline-title |title=Calpain 1 inhibitor BDA-410 ameliorates α-klotho-deficiency phenotypes resembling human aging-related syndromes. |date=01.08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25080854 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118420 }} * {{medline-title |title=[Bone metabolism and cardiovascular function update. α-klotho/[[FGF23]] system; a new insight into the field of mineral homeostasis and the pathogeneses of aging-associated syndromes and the complications of chronic kidney disease]. |date=07.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24976054 |full-text-url=https://sci-hub.do/CliCa140710051011 }} * {{medline-title |title=[Aging and inflammation: Klotho, diet and the kidney connection]. |date=2012 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24294726 }} * {{medline-title |title=Significance of the anti-aging protein Klotho. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24124751 |full-text-url=https://sci-hub.do/10.3109/09687688.2013.837518 }} * {{medline-title |title=[[FGF23]] affects the lineage fate determination of mesenchymal stem cells. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24068282 |full-text-url=https://sci-hub.do/10.1007/s00223-013-9795-6 }} * {{medline-title |title=Klotho and chronic kidney disease. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23652549 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911771 }} ==BRCA1== * {{medline-title |title=Babam2 Regulates Cell Cycle Progression and Pluripotency in Mouse Embryonic Stem Cells as Revealed by Induced DNA Damage. |date=10.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33050379 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600899 }} * {{medline-title |title=Declining BRCA-Mediated DNA Repair in Sperm Aging and its Prevention by Sphingosine-1-Phosphate. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31916095 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065969 }} * {{medline-title |title=BRCA-related [[ATM]]-mediated DNA double-strand break repair and ovarian aging. |date=01.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31822904 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935693 }} * {{medline-title |title=The [[RXFP3]] receptor is functionally associated with cellular responses to oxidative stress and DNA damage. |date=03.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31794429 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932917 }} * {{medline-title |title=Do [[BRCA1]] and [[BRCA2]] gene mutation carriers have a reduced ovarian reserve? Protocol for a prospective observational study. |date=25.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31772111 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887091 }} * {{medline-title |title=53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination. |date=02.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31653568 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993210 }} * {{medline-title |title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812 }} * {{medline-title |title=[[PML]] nuclear bodies are recruited to persistent DNA damage lesions in an [[RNF168]]-53BP1 dependent manner and contribute to DNA repair. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31009828 |full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.04.001 }} * {{medline-title |title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287 }} * {{medline-title |title=Klotho gene polymorphisms are associated with healthy aging and longevity: Evidence from a meta-analysis. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30633899 |full-text-url=https://sci-hub.do/10.1016/j.mad.2018.12.003 }} * {{medline-title |title=High expression of the breast cancer susceptibility gene [[BRCA1]] in long-lived termite kings. |date=11.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30312170 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224230 }} * {{medline-title |title=The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30235328 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147527 }} * {{medline-title |title=Cost effectiveness of population based [[BRCA1]] founder mutation testing in Sephardi Jewish women. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29288066 |full-text-url=https://sci-hub.do/10.1016/j.ajog.2017.12.221 }} * {{medline-title |title=Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions. |date=04.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29249653 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756112 }} * {{medline-title |title=Faulty [[BRCA1]], [[BRCA2]] genes: how poor is the prognosis? |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29017890 |full-text-url=https://sci-hub.do/10.1016/j.annepidem.2017.09.005 }} * {{medline-title |title=Ovarian Aging in Women With BRCA Germline Mutations. |date=01.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28938488 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630253 }} * {{medline-title |title=The expected benefit of preventive mastectomy on breast cancer incidence and mortality in BRCA mutation carriers, by age at mastectomy. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28914396 |full-text-url=https://sci-hub.do/10.1007/s10549-017-4476-1 }} * {{medline-title |title=A [[BRCA1]]-Dependent DNA Damage Response in the Regenerating Adult Peripheral Nerve Milieu. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28585187 |full-text-url=https://sci-hub.do/10.1007/s12035-017-0574-7 }} * {{medline-title |title=The Histone Variant MacroH2A1 Is a [[BRCA1]] Ubiquitin Ligase Substrate. |date=30.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28564596 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507409 }} * {{medline-title |title=A Multigene Test Could Cost-Effectively Help Extend Life Expectancy for Women at Risk of Hereditary Breast Cancer. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28407996 |full-text-url=https://sci-hub.do/10.1016/j.jval.2017.01.006 }} * {{medline-title |title=Serum [[AMH]] levels in healthy women from [[BRCA1]]/2 mutated families: are they reduced? |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27907901 |full-text-url=https://sci-hub.do/10.1093/humrep/dew242 }} * {{medline-title |title=p16INK4a suppresses [[BRCA1]]-deficient mammary tumorigenesis. |date=20.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27811360 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356676 }} * {{medline-title |title=BRCA-1 Gene Expression and Comparative Proteomic Profile of Primordial Follicles from Young and Adult Buffalo (Bubalus bubalis) Ovaries. |date=03.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27552356 |full-text-url=https://sci-hub.do/10.1080/10495398.2016.1210613 }} * {{medline-title |title=Women's preferences for contralateral prophylactic mastectomy: An investigation using protection motivation theory. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27529090 |full-text-url=https://sci-hub.do/10.1016/j.pec.2015.11.012 }} * {{medline-title |title=Accelerated geroncogenesis in hereditary breast-ovarian cancer syndrome. |date=15.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26943589 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914261 }} * {{medline-title |title=Genetic suppression reveals DNA repair-independent antagonism between [[BRCA1]] and COBRA1 in mammary gland development. |date=04.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26941120 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785232 }} * {{medline-title |title=Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and [[BRCA1]]-mediated DNA repair. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26414677 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661791 }} * {{medline-title |title=Comparative proteomic analysis of primordial follicles from ovaries of immature and aged rats. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26391928 |full-text-url=https://sci-hub.do/10.3109/19396368.2015.1077903 }} * {{medline-title |title=BRCA Mutations, DNA Repair Deficiency, and Ovarian Aging. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26224004 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710189 }} * {{medline-title |title=Increased DNA damage and repair deficiency in granulosa cells are associated with ovarian aging in rhesus monkey. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25957622 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531862 }} * {{medline-title |title=Targeting of DNA Damage Signaling Pathway Induced Senescence and Reduced Migration of Cancer cells. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24747666 |full-text-url=https://sci-hub.do/10.1093/gerona/glu019 }} * {{medline-title |title=Molecular adaptation of telomere associated genes in mammals. |date=15.11.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24237966 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833184 }} * {{medline-title |title=Copy neutral loss of heterozygosity is more frequent in older ovarian cancer patients. |date=09.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23716468 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767172 }} * {{medline-title |title=Impairment of [[BRCA1]]-related DNA double-strand break repair leads to ovarian aging in mice and humans. |date=13.02.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23408054 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130338 }} ==HMGB1== * {{medline-title |title=A Small Molecule Stabilizer of the [[MYC]] G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma. |date=13.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066043 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650714 }} * {{medline-title |title=Age-Dependent Changes of Adipokine and Cytokine Secretion From Rat Adipose Tissue by Endogenous and Exogenous Toll-Like Receptor Agonists. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32973755 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466552 }} * {{medline-title |title=Metformin decreases LPS-induced inflammatory response in rabbit annulus fibrosus stem/progenitor cells by blocking [[HMGB1]] release. |date=26.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31772144 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914423 }} * {{medline-title |title=Protective role of mesenchymal stem cells and mesenchymal stem cell-derived exosomes in cigarette smoke-induced mitochondrial dysfunction in mice. |date=15.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31678243 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894395 }} * {{medline-title |title=Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction. |date=02.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31633821 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885734 }} * {{medline-title |title=Senescence-induced immunophenotype, gene expression and electrophysiology changes in human amniocytes. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31478614 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815807 }} * {{medline-title |title=Targeting [[HMGB1]] by ethyl pyruvate ameliorates systemic lupus erythematosus and reverses the senescent phenotype of bone marrow-mesenchymal stem cells. |date=14.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31303606 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660056 }} * {{medline-title |title=[[HMGB1]] and Caveolin-1 related to [[RPE]] cell senescence in age-related macular degeneration. |date=07.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31284269 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660032 }} * {{medline-title |title=Dual faced [[HMGB1]] plays multiple roles in cardiomyocyte senescence and cardiac inflammatory injury. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31129019 |full-text-url=https://sci-hub.do/10.1016/j.cytogfr.2019.05.009 }} * {{medline-title |title=Neuroprotective Effect of Dioscin on the Aging Brain. |date=30.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30935017 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479446 }} * {{medline-title |title=Modulation of soluble receptor for advanced glycation end-products (RAGE) isoforms and their ligands in healthy aging. |date=23.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30903794 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461165 }} * {{medline-title |title=Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis. |date=30.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30910981 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500153 }} * {{medline-title |title=Serum and nutrient deprivation increase autophagic flux in intervertebral disc annulus fibrosus cells: an in vitro experimental study. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30847707 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538458 }} * {{medline-title |title=Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence. |date=01.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30735837 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2019.02.005 }} * {{medline-title |title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357 |full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004 }} * {{medline-title |title=Repeated abortion in adulthood induces cognition impairment in aged mice. |date=30.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30061639 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065382 }} * {{medline-title |title=Loss of DNA polymerase β induces cellular senescence. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29968395 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203593 }} * {{medline-title |title=Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of [[BDNF]]/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats. |date=06.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29065194 |full-text-url=https://sci-hub.do/10.1093/ntr/ntx157 }} * {{medline-title |title=Intestinal Permeability Biomarker Zonulin is Elevated in Healthy Aging. |date=01.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676292 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581307 }} * {{medline-title |title=Disruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28317237 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418188 }} * {{medline-title |title=Changes in pro-inflammatory markers and leucine concentrations in response to Nordic Walking training combined with vitamin D supplementation in elderly women. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28316011 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514208 }} * {{medline-title |title=Systemic [[HMGB1]] Neutralization Prevents Postoperative Neurocognitive Dysfunction in Aged Rats. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27822212 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075578 }} * {{medline-title |title=The Alarmin [[HMGB1]] Mediates Age-Induced Neuroinflammatory Priming. |date=27.07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27466339 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961779 }} * {{medline-title |title=Human fetal membranes at term: Dead tissue or signalers of parturition? |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27452431 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375105 }} * {{medline-title |title=Modulation of Macrophage Polarization and [[HMGB1]]-TLR2/[[TLR4]] Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27070323 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829159 }} * {{medline-title |title=DAMPs and influenza virus infection in ageing. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26200296 |full-text-url=https://sci-hub.do/10.1016/j.arr.2015.07.005 }} * {{medline-title |title=Decreased serum level of [[HMGB1]] and MyD88 during human aging progress in healthy individuals. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26130428 |full-text-url=https://sci-hub.do/10.1007/s40520-015-0402-8 }} * {{medline-title |title=[Peptides and [[CCL11]] and [[HMGB1]] as molecular markers of aging: literature review and own data]. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25826983 }} * {{medline-title |title=[[HMGB1]] facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice. |date=01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25510912 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309669 }} * {{medline-title |title=Secondhand smoke exposure-induced nucleocytoplasmic shuttling of [[HMGB1]] in a rat premature skin aging model. |date=02.01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25446104 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2014.11.040 }} * {{medline-title |title=Changes in the expression of the Toll-like receptor system in the aging rat kidneys. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24810370 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014502 }} * {{medline-title |title=Brain innate immunity in the regulation of neuroinflammation: therapeutic strategies by modulating [[CD200]]-[[CD200]]R interaction involve the cannabinoid system. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24588829 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157566 }} * {{medline-title |title=Postoperative impairment of cognitive function in old mice: a possible role for neuroinflammation mediated by [[HMGB1]], [[S100B]], and RAGE. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23899512 |full-text-url=https://sci-hub.do/10.1016/j.jss.2013.06.043 }} * {{medline-title |title=Neuroprotective effects of anti-high-mobility group box 1 antibody in juvenile rat hippocampus after kainic acid-induced status epilepticus. |date=02.10.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23839305 |full-text-url=https://sci-hub.do/10.1097/WNR.0b013e328363fed3 }} ==NPY== * {{medline-title |title=Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells. |date=22.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32012215 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243588 }} * {{medline-title |title=Molecular crosstalk between Y5 receptor and neuropeptide Y drives liver cancer. |date=01.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31999643 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190991 }} * {{medline-title |title=Effects of rikkunshito supplementation on resistance to oxidative stress and lifespan in mice. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31855319 |full-text-url=https://sci-hub.do/10.1111/ggi.13848 }} * {{medline-title |title=Effects of age on feeding response: Focus on the rostral C1 neuron and its glucoregulatory proteins. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31705967 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110779 }} * {{medline-title |title=Autophagy within the mushroom body protects from synapse aging in a non-cell autonomous manner. |date=21.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30899013 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428838 }} * {{medline-title |title=β-Alanine supplementation reduces anxiety and increases neurotrophin expression in both young and older rats. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30803507 |full-text-url=https://sci-hub.do/10.1016/j.nutres.2018.11.001 }} * {{medline-title |title=Age-related central regulation of orexin and [[NPY]] in the short-lived African killifish Nothobranchius furzeri. |date=15.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30666646 |full-text-url=https://sci-hub.do/10.1002/cne.24638 }} * {{medline-title |title=Chronic treatment with tributyltin induces sexually dimorphic alterations in the hypothalamic [[POMC]] system of adult mice. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30078105 |full-text-url=https://sci-hub.do/10.1007/s00441-018-2896-9 }} * {{medline-title |title=Expression of CGRP neurotransmitter and vascular genesis marker mRNA is age-dependent in superior cervical ganglia of senescence-accelerated prone mice. |date=18.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154859 |full-text-url=https://sci-hub.do/10.1016/j.neulet.2017.11.034 }} * {{medline-title |title=Comparing the Effects of Melatonin with Caloric Restriction in the Hippocampus of Aging Mice: Involvement of Sirtuin1 and the FOXOs Pathway. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28770437 |full-text-url=https://sci-hub.do/10.1007/s11064-017-2369-7 }} * {{medline-title |title=Bioactive growth hormone in older men and women: It's relationship to immune markers and healthspan. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28551577 |full-text-url=https://sci-hub.do/10.1016/j.ghir.2017.05.002 }} * {{medline-title |title=Retinal, [[NPY]]- and 5ht- inputs to the aged suprachiasmatic nucleus in common marmosets (Callithrix jacchus). |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28288865 |full-text-url=https://sci-hub.do/10.1016/j.neures.2017.03.005 }} * {{medline-title |title=Long-lasting memory deficits in mice withdrawn from cocaine are concomitant with neuroadaptations in hippocampal basal activity, GABAergic interneurons and adult neurogenesis. |date=01.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28138095 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374316 }} * {{medline-title |title=Neuropeptide Y resists excess loss of fat by lipolysis in calorie-restricted mice: a trait potential for the life-extending effect of calorie restriction. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28101970 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334538 }} * {{medline-title |title=Nerve growth factor-induced plasticity in medial prefrontal cortex interneurons of aged Wistar rats. |date=01.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27664582 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.09.017 }} * {{medline-title |title=Age Impaired endothelium-dependent vasodilation is improved by resveratrol in rat mesenteric arteries. |date=31.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27298812 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899900 }} * {{medline-title |title=Age-related changes in neurochemical components and retinal projections of rat intergeniculate leaflet. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26718202 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005876 }} * {{medline-title |title=Short photoperiod condition increases susceptibility to stress in adolescent male rats. |date=01.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26655789 |full-text-url=https://sci-hub.do/10.1016/j.bbr.2015.12.002 }} * {{medline-title |title=Neuropeptide Y: An Anti-Aging Player? |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26549884 |full-text-url=https://sci-hub.do/10.1016/j.tins.2015.08.012 }} * {{medline-title |title=Influence of Aging and Gender Differences on Feeding Behavior and Ghrelin-Related Factors during Social Isolation in Mice. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448274 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598162 }} * {{medline-title |title=Reduction in [[NPY]]-positive neurons and dysregulation of excitability in young senescence-accelerated mouse prone 8 (SAMP8) hippocampus precede the onset of cognitive impairment. |date=10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26250996 |full-text-url=https://sci-hub.do/10.1111/jnc.13274 }} * {{medline-title |title=Age effects on the nucleus of the lateral olfactory tract of the rat. |date=01.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26224652 |full-text-url=https://sci-hub.do/10.1002/cne.23863 }} * {{medline-title |title=[[NPY]]/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging? |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26086271 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590601 }} * {{medline-title |title=Analysis of gene expression during aging of CGNs in culture: implication of [[SLIT2]] and [[NPY]] in senescence. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26047956 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493715 }} * {{medline-title |title=Neuropeptide Y stimulates autophagy in hypothalamic neurons. |date=31.03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25775546 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386327 }} * {{medline-title |title=Effect of IP3R3 and [[NPY]] on age-related declines in olfactory stem cell proliferation. |date=02.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25482245 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315725 }} * {{medline-title |title=Old-onset caloric restriction effects on neuropeptide Y- and somatostatin-containing neurons and on cholinergic varicosities in the rat hippocampal formation. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25471895 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259091 }} * {{medline-title |title=Orally administered δ opioid agonist peptide rubiscolin-6 stimulates food intake in aged mice with ghrelin resistance. |date=10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25047666 |full-text-url=https://sci-hub.do/10.1002/mnfr.201400100 }} * {{medline-title |title=Ghrelin receptor regulates appetite and satiety during aging in mice by regulating meal frequency and portion size but not total food intake. |date=09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24991043 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130825 }} * {{medline-title |title=Distribution of peptidergic populations in the human dentate gyrus (somatostatin [SOM-28, SOM-12] and neuropeptide Y [[[NPY]]]) during postnatal development. |date=10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24965867 |full-text-url=https://sci-hub.do/10.1007/s00441-014-1929-2 }} * {{medline-title |title=Relative contribution of foetal and post-natal nutritional periods on feeding regulation in adult rats. |date=01.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24010762 |full-text-url=https://sci-hub.do/10.1111/apha.12163 }} * {{medline-title |title=Early life stress interacts with the diet deficiency of omega-3 fatty acids during the life course increasing the metabolic vulnerability in adult rats. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23614006 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629088 }} * {{medline-title |title=Nerve growth factor retrieves neuropeptide Y and cholinergic immunoreactivity in the nucleus accumbens of old rats. |date=08.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23540942 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2013.02.011 }} * {{medline-title |title=Aging and long-term caloric restriction regulate neuropeptide Y receptor subtype densities in the rat brain. |date=06.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23410741 |full-text-url=https://sci-hub.do/10.1016/j.npep.2013.01.001 }} ==WRN== * {{medline-title |title=The Impact of Vitamin C on Different System Models of Werner Syndrome. |date=17.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33202145 |full-text-url=https://sci-hub.do/10.1089/ars.2020.8147 }} * {{medline-title |title=[[WRN]] modulates translation by influencing nuclear mRNA export in HeLa cancer cells. |date=14.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33054770 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557079 }} * {{medline-title |title=[[MIB1]]-mediated degradation of [[WRN]] promotes cellular senescence in response to camptothecin treatment. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32652764 |full-text-url=https://sci-hub.do/10.1096/fj.202000268RRR }} * {{medline-title |title=A Case Report of Werner's Syndrome With a Novel Mutation From India. |date=08.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32528764 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282380 }} * {{medline-title |title=Evidence for premature aging in a Drosophila model of Werner syndrome. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31518666 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935377 }} * {{medline-title |title=Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31259468 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718529 }} * {{medline-title |title=Studying Werner syndrome to elucidate mechanisms and therapeutics of human aging and age-related diseases. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30666569 |full-text-url=https://sci-hub.do/10.1007/s10522-019-09798-2 }} * {{medline-title |title=Werner Syndrome Protein and DNA Replication. |date=02.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400178 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274846 }} * {{medline-title |title=A case report of Werner's syndrome with bilateral juvenile cataracts. |date=14.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30107835 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092780 }} * {{medline-title |title=Genomic instability and DNA replication defects in progeroid syndromes. |date=31.12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29936894 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000143 }} * {{medline-title |title=Nonfunctional mutant Wrn protein leads to neurological deficits, neuronal stress, microglial alteration, and immune imbalance in a mouse model of Werner syndrome. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29908963 |full-text-url=https://sci-hub.do/10.1016/j.bbi.2018.06.007 }} * {{medline-title |title=Acidic domain of [[WRN]]p is critical for autophagy and up-regulates age associated proteins. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29800817 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338341 }} * {{medline-title |title=RECQ helicase disease and related progeroid syndromes: RECQ2018 meeting. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29752965 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217841 }} * {{medline-title |title=Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29476423 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876188 }} * {{medline-title |title=Serum vitamin C levels modulate the lifespan and endoplasmic reticulum stress response pathways in mice synthesizing a nonfunctional mutant [[WRN]] protein. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452565 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998970 }} * {{medline-title |title=Werner syndrome ([[WRN]]) gene variants and their association with altered function and age-associated diseases. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29146545 |full-text-url=https://sci-hub.do/10.1016/j.arr.2017.11.003 }} * {{medline-title |title=Human RecQL4 helicase plays multifaceted roles in the genomic stability of normal and cancer cells. |date=28.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080750 |full-text-url=https://sci-hub.do/10.1016/j.canlet.2017.10.021 }} * {{medline-title |title=Recent Advances in Understanding Werner Syndrome. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29043077 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621106 }} * {{medline-title |title=Systematic analysis of DNA crosslink repair pathways during development and aging in Caenorhabditis elegans. |date=19.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28934497 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766164 }} * {{medline-title |title=The Werner Syndrome Helicase Coordinates Sequential Strand Displacement and [[FEN1]]-Mediated Flap Cleavage during Polymerase δ Elongation. |date=01.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27849570 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247617 }} * {{medline-title |title=Vitamin C alleviates aging defects in a stem cell model for Werner syndrome. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27271327 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930768 }} * {{medline-title |title=Bloom's syndrome: Why not premature aging?: A comparison of the [[BLM]] and [[WRN]] helicases. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27238185 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124422 }} * {{medline-title |title=Understanding Vascular Diseases: Lessons From Premature Aging Syndromes. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26948039 |full-text-url=https://sci-hub.do/10.1016/j.cjca.2015.12.003 }} * {{medline-title |title=Stem Cell Depletion by Global Disorganization of the H3K9me3 Epigenetic Marker in Aging. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26160351 |full-text-url=https://sci-hub.do/10.1089/rej.2015.1742 }} * {{medline-title |title=The Werner Protein Acts as a Coactivator of Nuclear Factor κB (NF-κB) on HIV-1 and Interleukin-8 (IL-8) Promoters. |date=24.07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26037922 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513100 }} * {{medline-title |title=Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging. |date=05.06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25931448 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494668 }} * {{medline-title |title=Werner Syndrome-specific induced pluripotent stem cells: recovery of telomere function by reprogramming. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25688260 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310323 }} * {{medline-title |title=Transient overexpression of Werner protein rescues starvation induced autophagy in Werner syndrome cells. |date=12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25257404 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582615 }} * {{medline-title |title=Senescence induced by [[RECQL4]] dysfunction contributes to Rothmund-Thomson syndrome features in mice. |date=15.05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24832598 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047874 }} * {{medline-title |title=Search and insights into novel genetic alterations leading to classical and atypical Werner syndrome. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24401204 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997596 }} * {{medline-title |title=Hydrogen sulfide restores a normal morphological phenotype in Werner syndrome fibroblasts, attenuates oxidative damage and modulates mTOR pathway. |date=08.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23702336 |full-text-url=https://sci-hub.do/10.1016/j.phrs.2013.04.011 }} * {{medline-title |title=Copy number variations of DNA repair genes and the age-related cataract: Jiangsu Eye Study. |date=01.02.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23329665 |full-text-url=https://sci-hub.do/10.1167/iovs.12-10948 }} * {{medline-title |title=The associations between single nucleotide polymorphisms of DNA repair genes, DNA damage, and age-related cataract: Jiangsu Eye Study. |date=01.02.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23322570 |full-text-url=https://sci-hub.do/10.1167/iovs.12-10940 }} * {{medline-title |title=Aberrant DNA methylation profiles in the premature aging disorders Hutchinson-Gilford Progeria and Werner syndrome. |date=01.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23257959 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549877 }} ==KL== * {{medline-title |title=Alignment of Alzheimer's disease amyloid β-peptide and klotho. |date=11-12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32999998 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521834 }} * {{medline-title |title=PTSD and the klotho longevity gene: Evaluation of longitudinal effects on inflammation via DNA methylation. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32438247 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293549 }} * {{medline-title |title=Epigenetic Regulation of [[KL]] (Klotho) via H3K27me3 (Histone 3 Lysine [K] 27 Trimethylation) in Renal Tubule Cells. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32223380 |full-text-url=https://sci-hub.do/10.1161/HYPERTENSIONAHA.120.14642 }} * {{medline-title |title=[[FGF23]] expression is stimulated in transgenic α-Klotho longevity mouse model. |date=05.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31801907 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962016 }} * {{medline-title |title=The goddess who spins the thread of life: Klotho, psychiatric stress, and accelerated aging. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872092 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660403 }} * {{medline-title |title=[i][[KL]]OTHO[/i] heterozygosity attenuates [i]APOE4[/i]-related amyloid burden in preclinical AD. |date=16.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30867273 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550504 }} * {{medline-title |title=Utilizing Atlas-Based Modeling to Predict Knee Joint Cartilage Degeneration: Data from the Osteoarthritis Initiative. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30547410 |full-text-url=https://sci-hub.do/10.1007/s10439-018-02184-y }} * {{medline-title |title=Impaired proteostasis in senescent vascular endothelial cells: a perspective on estrogen and oxidative stress in the aging vasculature. |date=01.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30499713 |full-text-url=https://sci-hub.do/10.1152/ajpheart.00318.2018 }} * {{medline-title |title=Leukocyte Telomere Length in Patients with Radiographic Knee Osteoarthritis. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30488497 |full-text-url=https://sci-hub.do/10.1002/em.22247 }} * {{medline-title |title=Klotho at the Edge of Alzheimer's Disease and Senile Depression. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29978424 |full-text-url=https://sci-hub.do/10.1007/s12035-018-1200-z }} * {{medline-title |title=Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29890178 |full-text-url=https://sci-hub.do/10.1016/j.mad.2018.06.002 }} * {{medline-title |title=G-395A polymorphism in the promoter region of the [[KL]]OTHO gene associates with frailty among the oldest-old. |date=30.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29712948 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928057 }} * {{medline-title |title=Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of [[RIG]]-I/NF-κB Signaling. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29403373 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778393 }} * {{medline-title |title=Changes in expression of klotho affect physiological processes, diseases, and cancer. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433 }} * {{medline-title |title=Anti-aging factor, serum alpha-Klotho, as a marker of acute physiological stress, and a predictor of ICU mortality, in patients with septic shock. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29268200 |full-text-url=https://sci-hub.do/10.1016/j.jcrc.2017.11.023 }} * {{medline-title |title=Secreted αKlotho isoform protects against age-dependent memory deficits. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29086766 |full-text-url=https://sci-hub.do/10.1038/mp.2017.211 }} * {{medline-title |title=Induction of anti-aging gene klotho with a small chemical compound that demethylates CpG islands. |date=18.07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28657902 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564520 }} * {{medline-title |title=Longevity Klotho gene polymorphism and the risk of dementia in older men. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28539162 |full-text-url=https://sci-hub.do/10.1016/j.maturitas.2017.04.005 }} * {{medline-title |title=Klotho, APOEε4, cognitive ability, brain size, atrophy, and survival: a study in the Aberdeen Birth Cohort of 1936. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28431289 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.02.019 }} * {{medline-title |title=The relevance of α-[[KL]]OTHO to the central nervous system: Some key questions. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28323064 |full-text-url=https://sci-hub.do/10.1016/j.arr.2017.03.003 }} * {{medline-title |title=Systemic klotho is associated with [[KL]]OTHO variation and predicts intrinsic cortical connectivity in healthy human aging. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27714549 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382127 }} * {{medline-title |title=Activation of [[SIRT1]] Attenuates Klotho Deficiency-Induced Arterial Stiffness and Hypertension by Enhancing AMP-Activated Protein Kinase Activity. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27620389 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063709 }} * {{medline-title |title=The [[FGF23]]/[[KL]]OTHO Regulatory Network and Its Roles in Human Disorders. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27125741 |full-text-url=https://sci-hub.do/10.1016/bs.vh.2016.02.001 }} * {{medline-title |title=Antiaging Gene Klotho Deficiency Promoted High-Fat Diet-Induced Arterial Stiffening via Inactivation of AMP-Activated Protein Kinase. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26781278 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752379 }} * {{medline-title |title=[[KL]]-optimal experimental design for discriminating between two growth models applied to a beef farm. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26776261 |full-text-url=https://sci-hub.do/10.3934/mbe.2016.13.67 }} * {{medline-title |title=Secreted and Transmembrane αKlotho Isoforms Have Different Spatio-Temporal Profiles in the Brain during Aging and Alzheimer's Disease Progression. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26599613 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658185 }} * {{medline-title |title=Genetic Variants in [[KL]]OTHO Associate With Cognitive Function in the Oldest Old Group. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26405063 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978356 }} * {{medline-title |title=Molecular basis of Klotho: from gene to function in aging. |date=04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25695404 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399270 }} * {{medline-title |title=Life extension factor klotho enhances cognition. |date=22.05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24813892 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176932 }} * {{medline-title |title=Quadriceps intramuscular fat fraction rather than muscle size is associated with knee osteoarthritis. |date=02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24361743 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932784 }} * {{medline-title |title=Biochemical and functional characterization of the klotho-VS polymorphism implicated in aging and disease risk. |date=20.12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24217253 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868745 }} * {{medline-title |title=Association of Klotho polymorphisms with healthy aging: a systematic review and meta-analysis. |date=04.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24164579 |full-text-url=https://sci-hub.do/10.1089/rej.2013.1523 }} * {{medline-title |title=Serum [[KL]]-6 concentrations are associated with molecular sizes and efflux behavior of [[KL]]-6/[[MUC1]] in healthy subjects. |date=23.09.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23778023 |full-text-url=https://sci-hub.do/10.1016/j.cca.2013.06.002 }} ==SIRT2== * {{medline-title |title=NAD Repletion Rescues Female Fertility during Reproductive Aging. |date=11.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32049001 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063679 }} * {{medline-title |title=Melatonin ameliorates the advanced maternal age-associated meiotic defects in oocytes through the [[SIRT2]]-dependent H4K16 deacetylation pathway. |date=24.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31980591 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053624 }} * {{medline-title |title=Context-Dependent Roles for [[SIRT2]] and [[SIRT3]] in Tumor Development Upon Calorie Restriction or High Fat Diet. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31970087 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960403 }} * {{medline-title |title=[[SIRT2]] functions in aging, autophagy, and apoptosis in post-maturation bovine oocytes. |date=01.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31295472 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116639 }} * {{medline-title |title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296 }} * {{medline-title |title=Mitochondrial Stress-Initiated Aberrant Activation of the [[NLRP3]] Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging. |date=22.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30673616 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371804 }} * {{medline-title |title=Hsp90 Stabilizes [[SIRT1]] Orthologs in Mammalian Cells and [i]C. elegans[/i]. |date=20.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463299 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274930 }} * {{medline-title |title=Tenovin-1 Induces Senescence and Decreases Wound-Healing Activity in Cultured Rat Primary Astrocytes. |date=01.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30092626 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513186 }} * {{medline-title |title=High expression of CPT1b in skeletal muscle in metabolically healthy older subjects. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29657112 |full-text-url=https://sci-hub.do/10.1016/j.diabet.2018.01.018 }} * {{medline-title |title=Expression of Sirtuins in the Retinal Neurons of Mice, Rats, and Humans. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29249955 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715387 }} * {{medline-title |title=Loss of [[SIRT2]] leads to axonal degeneration and locomotor disability associated with redox and energy imbalance. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28984064 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676070 }} * {{medline-title |title=[[SIRT2]] Acts as a Cardioprotective Deacetylase in Pathological Cardiac Hypertrophy. |date=21.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28947430 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698109 }} * {{medline-title |title=Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28767699 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540417 }} * {{medline-title |title=Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27882448 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357501 }} * {{medline-title |title=Resistance training and redox homeostasis: Correlation with age-associated genomic changes. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27687219 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040637 }} * {{medline-title |title=Aging-related 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurochemial and behavioral deficits and redox dysfunction: improvement by AK-7. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27235848 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.05.011 }} * {{medline-title |title=Increased expression of [[SIRT2]] is a novel marker of cellular senescence and is dependent on wild type p53 status. |date=17.07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27229617 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968900 }} * {{medline-title |title=Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins. |date=15.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27038700 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.03.015 }} * {{medline-title |title=Sirtuins, Cell Senescence, and Vascular Aging. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26948035 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848124 }} * {{medline-title |title=The expression levels of the sirtuins in patients with BCC. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26631040 |full-text-url=https://sci-hub.do/10.1007/s13277-015-4522-8 }} * {{medline-title |title=Effects of Aging and Cardiovascular Disease Risk Factors on the Expression of Sirtuins in the Human Corpus Cavernosum. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26556180 |full-text-url=https://sci-hub.do/10.1111/jsm.13035 }} * {{medline-title |title=Localization of sirtuins ([[SIRT1]]-7) in the aged mouse inner ear. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26472659 |full-text-url=https://sci-hub.do/10.3109/00016489.2015.1093172 }} * {{medline-title |title=Aging-related rotenone-induced neurochemical and behavioral deficits: role of [[SIRT2]] and redox imbalance, and neuroprotection by AK-7. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26089639 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466888 }} * {{medline-title |title=Differential expression of sirtuins in the aging rat brain. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26005404 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424846 }} * {{medline-title |title=Polymorphisms Falling Within Putative miRNA Target Sites in the 3'UTR Region of [[SIRT2]] and [[DRD2]] Genes Are Correlated With Human Longevity. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25934993 |full-text-url=https://sci-hub.do/10.1093/gerona/glv058 }} * {{medline-title |title=The role of melatonin, sirtuin2 and FoXO1 transcription factor in the aging process of colon in male rats. |date=02.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25430724 |full-text-url=https://sci-hub.do/10.1007/s10522-014-9540-1 }} * {{medline-title |title=[[[SIRT2]], a multi-talented deacetylase]. |date=05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24939540 |full-text-url=https://sci-hub.do/10.1051/medsci/20143005016 }} * {{medline-title |title=[[SIRT2]] induces the checkpoint kinase BubR1 to increase lifespan. |date=01.07.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24825348 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194088 }} * {{medline-title |title=Forever young: [[SIRT3]] a shield against mitochondrial meltdown, aging, and neurodegeneration. |date=06.09.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24046746 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764375 }} * {{medline-title |title=Dietary restriction increases protein acetylation in the livers of aged rats. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24008504 |full-text-url=https://sci-hub.do/10.1159/000354087 }} * {{medline-title |title=Transcriptional and phenotypic changes in aorta and aortic valve with aging and MnSOD deficiency in mice. |date=15.11.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23997094 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840262 }} * {{medline-title |title=Growth hormone and melatonin prevent age-related alteration in apoptosis processes in the dentate gyrus of male rats. |date=08.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23852044 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739870 }} ==TFAM== * {{medline-title |title=Effect of aging on mitochondria and metabolism of bovine granulosa cells. |date=13.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32921645 |full-text-url=https://sci-hub.do/10.1262/jrd.2020-071 }} * {{medline-title |title=Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32748504 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399374 }} * {{medline-title |title=Mitochondrial nucleoid remodeling and biogenesis are regulated by the p53-p21 -PKCζ pathway in p16 -silenced cells. |date=24.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32330121 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202532 }} * {{medline-title |title=Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training. |date=01.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31306740 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707857 }} * {{medline-title |title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice. |date=08.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209 |full-text-url=https://sci-hub.do/10.1093/humrep/dez054 }} * {{medline-title |title=Differences in Liver [[TFAM]] Binding to mtDNA and mtDNA Damage between Aged and Extremely Aged Rats. |date=27.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31137890 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566948 }} * {{medline-title |title=Photobiomodulation and Coenzyme Q Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30983970 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434313 }} * {{medline-title |title=[A study on alterations in mitochondrial biological characteristics during cellular senescence of human embryonic lung fibroblasts]. |date=06.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30841673 |full-text-url=https://sci-hub.do/10.3760/cma.j.issn.0253-9624.2019.03.014 }} * {{medline-title |title=Changes in Stemness Properties, Differentiation Potential, Oxidative Stress, Senescence and Mitochondrial Function in Wharton's Jelly Stem Cells of Umbilical Cords of Mothers with Gestational Diabetes Mellitus. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30645713 |full-text-url=https://sci-hub.do/10.1007/s12015-019-9872-y }} * {{medline-title |title=Cycling CD4 T cells in HIV-infected immune nonresponders have mitochondrial dysfunction. |date=01.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320604 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205369 }} * {{medline-title |title=Increased [[TFAM]] binding to mtDNA damage hot spots is associated with mtDNA loss in aged rat heart. |date=20.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29969715 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319621 }} * {{medline-title |title=Restoring mitochondrial DNA copy number preserves mitochondrial function and delays vascular aging in mice. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29745022 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052475 }} * {{medline-title |title=Sestrin2 prevents age-related intolerance to post myocardial infarction via AMPK/[[PGC]]-1α pathway. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325933 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820139 }} * {{medline-title |title=Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203401 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.022 }} * {{medline-title |title=Dietary supplementation with acetyl-l-carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807823 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.017 }} * {{medline-title |title=Effect of lifelong football training on the expression of muscle molecular markers involved in healthy longevity. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28251397 |full-text-url=https://sci-hub.do/10.1007/s00421-017-3562-8 }} * {{medline-title |title=Regulation of mitochondrial gene expression, the epigenetic enigma. |date=01.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199194 |full-text-url=https://sci-hub.do/10.2741/4535 }} * {{medline-title |title=Poor embryo development in post-ovulatory in vivo-aged mouse oocytes is associated with mitochondrial dysfunction, but mitochondrial transfer from somatic cells is not sufficient for rejuvenation. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27591230 |full-text-url=https://sci-hub.do/10.1093/humrep/dew203 }} * {{medline-title |title=Disentangling the effect of dietary restriction on mitochondrial function using recombinant inbred mice. |date=05.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27597651 |full-text-url=https://sci-hub.do/10.1016/j.mce.2016.09.001 }} * {{medline-title |title="What makes some rats live so long?" The mitochondrial contribution to longevity through balance of mitochondrial dynamics and mtDNA content. |date=01.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27620821 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922457 }} * {{medline-title |title=Response of [[BAX]], Bcl-2 Proteins, and [[SIRT1]]/[[PGC]]-1α mRNA Expression to 8-Week Treadmill Running in the Aging Rat Skeletal Muscle. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27526155 |full-text-url=https://sci-hub.do/10.1007/978-3-319-38810-6_38 }} * {{medline-title |title=Methylene blue improves sensorimotor phenotype and decreases anxiety in parallel with activating brain mitochondria biogenesis in mid-age mice. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27515402 |full-text-url=https://sci-hub.do/10.1016/j.neures.2016.07.006 }} * {{medline-title |title=HIF-1 regulates insect lifespan extension by inhibiting c-Myc-[[TFAM]] signaling and mitochondrial biogenesis. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27469241 |full-text-url=https://sci-hub.do/10.1016/j.bbamcr.2016.07.007 }} * {{medline-title |title=Resistance exercise training and in vitro skeletal muscle oxidative capacity in older adults. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27405968 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945835 }} * {{medline-title |title=Mitochondrial Lon protease in human disease and aging: Including an etiologic classification of Lon-related diseases and disorders. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27387767 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183306 }} * {{medline-title |title=Resveratrol attenuates senescence of adipose-derived mesenchymal stem cells and restores their paracrine effects on promoting insulin secretion of [[INS]]-1 cells through Pim-1. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27049278 }} * {{medline-title |title=Regulation of mitochondrial biogenesis through [[TFAM]]-mitochondrial DNA interactions: Useful insights from aging and calorie restriction studies. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26437364 |full-text-url=https://sci-hub.do/10.1016/j.mito.2015.10.001 }} * {{medline-title |title=Dietary Tocotrienol/γ-Cyclodextrin Complex Increases Mitochondrial Membrane Potential and ATP Concentrations in the Brains of Aged Mice. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26301044 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537756 }} * {{medline-title |title=A comparison among the tissue-specific effects of aging and calorie restriction on [[TFAM]] amount and [[TFAM]]-binding activity to mtDNA in rat. |date=07.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24631828 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335656 }} * {{medline-title |title=Partial reversal of skeletal muscle aging by restoration of normal NAD⁺ levels. |date=02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24410488 |full-text-url=https://sci-hub.do/10.1089/rej.2014.1546 }} * {{medline-title |title=Aging and calorie restriction oppositely affect mitochondrial biogenesis through [[TFAM]] binding at both origins of mitochondrial DNA replication in rat liver. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24058615 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772924 }} ==ATF4== * {{medline-title |title=Endoplasmic Reticulum Stress Mediates Vascular Smooth Muscle Cell Calcification via Increased Release of Grp78-Loaded Extracellular Vesicles. |date=10.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33297752 |full-text-url=https://sci-hub.do/10.1161/ATVBAHA.120.315506 }} * {{medline-title |title=Verification of Resveratrol Inhibits Intestinal Aging by Downregulating [[ATF4]]/Chop/Bcl-2/Bax Signaling Pathway: Based on Network Pharmacology and Animal Experiment. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32754039 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366860 }} * {{medline-title |title=Decline in testicular function in ageing rats: Changes in the unfolded protein response and mitochondrial apoptotic pathway. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31491500 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110721 }} * {{medline-title |title=Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31310445 |full-text-url=https://sci-hub.do/10.1111/pcmr.12811 }} * {{medline-title |title=Chronic and age-dependent effects of the spongiform neurodegeneration-associated [[MGRN1]] E3 ubiquitin ligase on mitochondrial homeostasis. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31089807 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639055 }} * {{medline-title |title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009 |full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6 }} * {{medline-title |title=Effects of a resistance-training programme on endoplasmic reticulum unfolded protein response and mitochondrial functions in PBMCs from elderly subjects. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30614406 |full-text-url=https://sci-hub.do/10.1080/17461391.2018.1561950 }} * {{medline-title |title=[Protective effect of Wuzi Yanzong recipe on testicular germ cell apoptosis in natural ageing rats through endoplasmic reticulum stress]. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30453716 |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180530.001 }} * {{medline-title |title=Protective effect of Wuzi Yanzong recipe on testicular dysfunction through inhibition of germ cell apoptosis in ageing rats via endoplasmic reticulum stress. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30393883 |full-text-url=https://sci-hub.do/10.1111/and.13181 }} * {{medline-title |title=Loss of NRF-2 and [[PGC]]-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30253279 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156745 }} * {{medline-title |title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528 }} * {{medline-title |title=De-silencing [i]Grb10[/i] contributes to acute ER stress-induced steatosis in mouse liver. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29555819 |full-text-url=https://sci-hub.do/10.1530/JME-18-0018 }} * {{medline-title |title=Resveratrol modulates response against acute inflammatory stimuli in aged mouse brain. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29174969 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.014 }} * {{medline-title |title=Integrated stress response stimulates [[FGF21]] expression: Systemic enhancer of longevity. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28844867 |full-text-url=https://sci-hub.do/10.1016/j.cellsig.2017.08.009 }} * {{medline-title |title=Role of [[ATF4]] in skeletal muscle atrophy. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28376050 |full-text-url=https://sci-hub.do/10.1097/MCO.0000000000000362 }} * {{medline-title |title=4E-BP is a target of the GCN2-[[ATF4]] pathway during Drosophila development and aging. |date=02.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27979906 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223598 }} * {{medline-title |title=Diaminodiphenyl sulfone-induced parkin ameliorates age-dependent dopaminergic neuronal loss. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27103513 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2015.11.008 }} * {{medline-title |title=Different Roles of Negative and Positive Components of the Circadian Clock in Oncogene-induced Neoplastic Transformation. |date=13.05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26961881 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865904 }} * {{medline-title |title=Differentiated embryo chondrocyte 1 (DEC1) is a novel negative regulator of hepatic fibroblast growth factor 21 ([[FGF21]]) in aging mice. |date=15.01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26697751 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.12.045 }} * {{medline-title |title=Unfolded protein response is activated in aged retinas. |date=16.11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26467812 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679557 }} * {{medline-title |title=Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 ([[ATF4]])-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy. |date=16.10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26338703 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646196 }} * {{medline-title |title=Effect of mitochondrial stress on systemic metabolism. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26100439 |full-text-url=https://sci-hub.do/10.1111/nyas.12822 }} * {{medline-title |title=Senescence may mediate conversion of tau phosphorylation-induced apoptotic escape to neurodegeneration. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25777063 |full-text-url=https://sci-hub.do/10.1016/j.exger.2015.03.007 }} * {{medline-title |title=Impact of ER stress-regulated [[ATF4]]/p16 signaling on the premature senescence of renal tubular epithelial cells in diabetic nephropathy. |date=15.04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25567807 |full-text-url=https://sci-hub.do/10.1152/ajpcell.00096.2014 }} * {{medline-title |title=[[ATF4]] activity: a common feature shared by many kinds of slow-aging mice. |date=12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25156122 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326926 }} * {{medline-title |title=The unfolded protein response is triggered following a single, unaccustomed resistance-exercise bout. |date=15.09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25009220 |full-text-url=https://sci-hub.do/10.1152/ajpregu.00511.2013 }} * {{medline-title |title=Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21. |date=10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24935677 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331744 }} * {{medline-title |title=The first international mini-symposium on methionine restriction and lifespan. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24847356 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023024 }} * {{medline-title |title=Elevated [[ATF4]] function in fibroblasts and liver of slow-aging mutant mice. |date=03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24691093 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351389 }} * {{medline-title |title=Association analyses of insulin signaling pathway gene polymorphisms with healthy aging and longevity in Americans of Japanese ancestry. |date=03.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23770741 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968832 }} ==CDKN2A== * {{medline-title |title=Association between Nrf2 and [[[[CDKN2A]]]] expression in patients with end-stage renal disease: a pilot study. |date=13.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32661200 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485736 }} * {{medline-title |title=Contribution of senescence in human endometrial stromal cells during proliferative phase to embryo receptivity†. |date=23.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32285109 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313258 }} * {{medline-title |title=Chlorella vulgaris modulates the expression of senescence-associated genes in replicative senescence of human diploid fibroblasts. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31642042 |full-text-url=https://sci-hub.do/10.1007/s11033-019-05140-8 }} * {{medline-title |title=Astrocyte senescence may drive alterations in GFAPα, [[[[CDKN2A]]]] p14 , and TAU3 transcript expression and contribute to cognitive decline. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31654269 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885035 }} * {{medline-title |title=Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31385397 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826141 }} * {{medline-title |title=Analysis of the putative tumor suppressor gene cdkn2ab in pigment cells and melanoma of Xiphophorus and medaka. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30117276 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377863 }} * {{medline-title |title=In vitro behavior and UV response of melanocytes derived from carriers of [[[[CDKN2A]]]] mutations and [[MC1R]] variants. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30117292 |full-text-url=https://sci-hub.do/10.1111/pcmr.12732 }} * {{medline-title |title=Endothelial PPARγ (Peroxisome Proliferator-Activated Receptor-γ) Is Essential for Preventing Endothelial Dysfunction With Aging. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29735632 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002945 }} * {{medline-title |title=Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16 inactivation. |date=26.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482580 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828408 }} * {{medline-title |title=Cellular aging dynamics after acute malaria infection: A 12-month longitudinal study. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29143441 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771395 }} * {{medline-title |title=[[ARID1A]] suppresses malignant transformation of human pancreatic cells via mediating senescence-associated miR-503/[[[[CDKN2A]]]] regulatory axis. |date=18.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28942143 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.09.099 }} * {{medline-title |title=Cellular Senescence in Mouse Hippocampus After Irradiation and the Role of p53 and p21. |date=01.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28340115 |full-text-url=https://sci-hub.do/10.1093/jnen/nlx006 }} * {{medline-title |title=Identification of the activating cytotoxicity receptor NKG2D as a senescence marker in zero-hour kidney biopsies is indicative for clinical outcome. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28233611 |full-text-url=https://sci-hub.do/10.1016/j.kint.2016.12.018 }} * {{medline-title |title=ETS Proto-oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin-dependent Kinase Inhibitor 2A. |date=24.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28184004 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377799 }} * {{medline-title |title=Establishment and application of a novel patient-derived KIAA1549:[[BRAF]]-driven pediatric pilocytic astrocytoma model for preclinical drug testing. |date=14.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28002790 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355278 }} * {{medline-title |title=Induction of DNA double-strand breaks and cellular senescence by human respiratory syncytial virus. |date=18.05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26809688 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871660 }} * {{medline-title |title=Targeting genes in insulin-associated signalling pathway, DNA damage, cell proliferation and cell differentiation pathways by tocotrienol-rich fraction in preventing cellular senescence of human diploid fibroblasts. |date=11-12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26794818 |full-text-url=https://sci-hub.do/10.7417/T.2015.1902 }} * {{medline-title |title=Alterations of telomere length and DNA methylation in hairdressers: A cross-sectional study. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26637967 |full-text-url=https://sci-hub.do/10.1002/em.21991 }} * {{medline-title |title=Genetics of melanoma progression: the rise and fall of cell senescence. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26386262 |full-text-url=https://sci-hub.do/10.1111/pcmr.12422 }} * {{medline-title |title=Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis. |date=02.11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26391655 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824610 }} * {{medline-title |title=Genomic regulation of senescence and innate immunity signaling in the retinal pigment epithelium. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25963977 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450138 }} * {{medline-title |title=Y-27632, a ROCK inhibitor, delays senescence of putative murine salivary gland stem cells in culture. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25804560 |full-text-url=https://sci-hub.do/10.1016/j.archoralbio.2015.03.003 }} * {{medline-title |title=Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex. |date=29.05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24876127 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071561 }} * {{medline-title |title=Nodes and biological processes identified on the basis of network analysis in the brain of the senescence accelerated mice as an Alzheimer's disease animal model. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24194717 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810591 }} * {{medline-title |title=Id4 promotes senescence and sensitivity to doxorubicin-induced apoptosis in DU145 prostate cancer cells. |date=10.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24122992 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042247 }} * {{medline-title |title=Ocular parameters of biological ageing in HIV-infected individuals in South Africa: relationship with chronological age and systemic biomarkers of ageing. |date=09.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23994067 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818088 }} * {{medline-title |title=CDK4/6-inhibiting drug substitutes for p21 and p16 in senescence: duration of cell cycle arrest and [[MTOR]] activity determine geroconversion. |date=15.09.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23974099 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875680 }} * {{medline-title |title=Accelerated biological ageing in HIV-infected individuals in South Africa: a case-control study. |date=24.09.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23751258 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805356 }} * {{medline-title |title=Assessment of candidate ocular biomarkers of ageing in a South African adult population: relationship with chronological age and systemic biomarkers. |date=07-08.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23701820 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710972 }} * {{medline-title |title=Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes. |date=15.08.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23707792 |full-text-url=https://sci-hub.do/10.1016/j.mce.2013.05.003 }} ==COMT== * {{medline-title |title=Cortical thickness mediates the relationship between [[DRD2]] C957T polymorphism and executive function across the adult lifespan. |date=11.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33179159 |full-text-url=https://sci-hub.do/10.1007/s00429-020-02169-5 }} * {{medline-title |title=The geriatric pain experience in mice: intact cutaneous thresholds but altered responses to tonic and chronic pain. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32008855 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.12.018 }} * {{medline-title |title=A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30706571 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608707 }} * {{medline-title |title=Frontoparietal cortical thickness mediates the effect of [[COMT]] Val Met polymorphism on age-associated executive function. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30342271 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251730 }} * {{medline-title |title=[MELATONIN: THE POSSIBILITY TO ANALYSE THE MARKER OF AGE-RELATED PATHOLOGY IN THE BUCCAL EPITHELIUM AND URINE]. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30303666 }} * {{medline-title |title=The Moderating Role of [[COMT]] and [[BDNF]] Polymorphisms on Transfer Effects Following Multi- and Single-Domain Cognitive Training Among Community-Dwelling Shanghainese Older Adults. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30026692 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041383 }} * {{medline-title |title=Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29865048 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263481 }} * {{medline-title |title=Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29637543 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105503 }} * {{medline-title |title=Genetic Biomarkers on Age-Related Cognitive Decline. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307 }} * {{medline-title |title=A genetic variant in the catechol-O-methyl transferase ([[COMT]]) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28746172 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627798 }} * {{medline-title |title=Catechol-O-Methyltransferase Genotype and Gait Speed Changes over 10 Years in Older Adults. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28640434 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603384 }} * {{medline-title |title=[Melatonin as a molecular marker of age-related pathologies]. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28557392 }} * {{medline-title |title=Chloroplast overexpression of rice caffeic acid O-methyltransferase increases melatonin production in chloroplasts via the 5-methoxytryptamine pathway in transgenic rice plants. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28378373 |full-text-url=https://sci-hub.do/10.1111/jpi.12412 }} * {{medline-title |title=Age-dependent role of pre- and perinatal factors in interaction with genes on ADHD symptoms across adolescence. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28259004 |full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2017.02.014 }} * {{medline-title |title=Age differences in arterial and venous extra-cerebral blood flow in healthy adults: contributions of vascular risk factors and genetic variants. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28120105 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548544 }} * {{medline-title |title=Executive function performance and change in aging is predicted by apolipoprotein E, intensified by catechol-O-methyltransferase and brain-derived neurotrophic factor, and moderated by age and lifestyle. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28131014 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359032 }} * {{medline-title |title=Age-Dependent Effects of Catechol-O-Methyltransferase ([[COMT]]) Gene Val158Met Polymorphism on Language Function in Developing Children. |date=01.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27909011 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044402 }} * {{medline-title |title=Aging and the genetic road towards the positivity effect in memory. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27350108 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.06.011 }} * {{medline-title |title=Older age may offset genetic influence on affect: The [[COMT]] polymorphism and affective well-being across the life span. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27111524 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850911 }} * {{medline-title |title=Differential effect of age on posterior and anterior hippocampal functional connectivity. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27034025 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889536 }} * {{medline-title |title=Pulse Pressure Magnifies the Effect of [[COMT]] Val(158)Met on 15 Years Episodic Memory Trajectories. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26973509 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773588 }} * {{medline-title |title=Modulative effects of [[COMT]] haplotype on age-related associations with brain morphology. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26920810 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867428 }} * {{medline-title |title=[[COMT]] Val158Met polymorphism is associated with blood pressure and lipid levels in general families of Bama longevous area in China. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26823844 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713630 }} * {{medline-title |title=Genetic Basis of the Relationship Between Reproduction and Longevity: A Study on Common Variants of Three Genes in Steroid Hormone Metabolism--CYP17, [[HSD17B1]], and [[COMT]]. |date=10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25936248 |full-text-url=https://sci-hub.do/10.1089/rej.2015.1665 }} * {{medline-title |title=Cognitive ability, intraindividual variability, and common genetic variants of catechol-O-methyltransferase and brain-derived neurotrophic factor: a longitudinal study in a population-based sample of older adults. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24956006 |full-text-url=https://sci-hub.do/10.1037/a0035702 }} * {{medline-title |title=Healthy aging increases the cognitive effects of two genes that influence extracellular dopamine. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24956005 |full-text-url=https://sci-hub.do/10.1037/a0036109 }} * {{medline-title |title=[[BDNF]] and [[COMT]] polymorphisms have a limited association with episodic memory performance or engagement in complex cognitive activity in healthy older adults. |date=04.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24468545 |full-text-url=https://sci-hub.do/10.1016/j.nlm.2014.01.013 }} * {{medline-title |title=Age-related and genetic modulation of frontal cortex efficiency. |date=04.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24236764 |full-text-url=https://sci-hub.do/10.1162/jocn_a_00521 }} * {{medline-title |title=[[COMT]] polymorphism and memory dedifferentiation in old age. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23834492 |full-text-url=https://sci-hub.do/10.1037/a0033225 }} * {{medline-title |title=Genetic effects on old-age cognitive functioning: a population-based study. |date=03.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23276211 |full-text-url=https://sci-hub.do/10.1037/a0030829 }} ==TLR2== * {{medline-title |title=Changes in salivary microbial sensing proteins [[CD14]] and [[TLR2]] with aging. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32529494 |full-text-url=https://sci-hub.do/10.1007/s00784-020-03274-9 }} * {{medline-title |title=Association of TLR gene variants in a Czech Red Pied cattle population with reproductive traits. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31901560 |full-text-url=https://sci-hub.do/10.1016/j.vetimm.2019.109997 }} * {{medline-title |title=Culture Model for Non-human Primate Choroid Plexus. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31555096 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724611 }} * {{medline-title |title=Changes in fetal membrane histology with cervical insufficiency and transabdominal cerclage. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31004354 |full-text-url=https://sci-hub.do/10.1002/ijgo.12826 }} * {{medline-title |title=Aging leads to dysfunctional innate immune responses to [[TLR2]] and [[TLR4]] agonists. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30402800 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504629 }} * {{medline-title |title=The Synergy of Aging and LPS Exposure in a Mouse Model of Parkinson's Disease. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30271656 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147589 }} * {{medline-title |title=Aging modulates microglia phenotypes in neuroinflammation of MPTP-PD mice. |date=01.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30009921 |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.07.010 }} * {{medline-title |title=Toll-like receptor 2 deficiency hyperactivates the FoxO1 transcription factor and induces aging-associated cardiac dysfunction in mice. |date=24.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29929978 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109936 }} * {{medline-title |title=Cryopreserved whole blood for the quantification of monocyte, T-cell and NK-cell subsets, and monocyte receptor expression by multi-color flow cytometry: A methodological study based on participants from the canadian longitudinal study on aging. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29624852 |full-text-url=https://sci-hub.do/10.1002/cyto.a.23372 }} * {{medline-title |title=[[TLR4]] and [[TLR2]] activation is differentially associated with age during Parkinson's disease. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29077524 |full-text-url=https://sci-hub.do/10.1080/08820139.2017.1379024 }} * {{medline-title |title=Role of pattern recognition receptors of the neurovascular unit in inflamm-aging. |date=01.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28801521 |full-text-url=https://sci-hub.do/10.1152/ajpheart.00106.2017 }} * {{medline-title |title=Ionizing radiation reduces [[ADAM10]] expression in brain microvascular endothelial cells undergoing stress-induced senescence. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28437250 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425125 }} * {{medline-title |title=Aging-related Atg5 defect impairs neutrophil extracellular traps formation. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28375544 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506403 }} * {{medline-title |title=Chronoinflammaging in Alzheimer; A systematic review on the roles of toll like receptor 2. |date=15.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28087373 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2017.01.003 }} * {{medline-title |title=Aged B cells alter immune regulation of allografts in mice. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27546296 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366259 }} * {{medline-title |title=Estrogen receptors alpha mediates postischemic inflammation in chronically estrogen-deprived mice. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26973103 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2016.01.002 }} * {{medline-title |title=Effects of aerobic training on markers of autophagy in the elderly. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26940016 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005904 }} * {{medline-title |title=Reduced levels of cytosolic DNA sensor [[AIM2]] are associated with impaired cytokine responses in healthy elderly. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26944367 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.02.016 }} * {{medline-title |title=Immune ageing and susceptibility to Streptococcus pneumoniae. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26472172 |full-text-url=https://sci-hub.do/10.1007/s10522-015-9614-8 }} * {{medline-title |title=Monocyte Phenotype and Polyfunctionality Are Associated With Elevated Soluble Inflammatory Markers, Cytomegalovirus Infection, and Functional and Cognitive Decline in Elderly Adults. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26286603 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007736 }} * {{medline-title |title=Cathelicidin related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25834936 |full-text-url=https://sci-hub.do/10.1016/j.patbio.2015.03.002 }} * {{medline-title |title=Prophylactic lithium alleviates splenectomy-induced cognitive dysfunction possibly by inhibiting hippocampal [[TLR4]] activation in aged rats. |date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25839444 |full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2015.02.008 }} * {{medline-title |title=Altered neutrophil functions in elderly patients during a 6-month follow-up period after a hip fracture. |date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25797136 |full-text-url=https://sci-hub.do/10.1016/j.exger.2015.03.009 }} * {{medline-title |title=Aging does not affect the ability of human monocyte-derived dendritic cells to phagocytose Candida albicans. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25783173 |full-text-url=https://sci-hub.do/10.1007/s40520-015-0344-1 }} * {{medline-title |title=Cardiac autonomic dysfunction: particulate air pollution effects are modulated by epigenetic immunoregulation of Toll-like receptor 2 and dietary flavonoid intake. |date=27.01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25628407 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330067 }} * {{medline-title |title=Bacteria and Toll-like receptor and cytokine mRNA expression profiles associated with canine arthritis. |date=15.08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24856731 |full-text-url=https://sci-hub.do/10.1016/j.vetimm.2014.04.004 }} * {{medline-title |title=Innate immune activation in the pathogenesis of a murine model of globoid cell leukodystrophy. |date=02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24316110 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906490 }} * {{medline-title |title=Dendritic cells from the elderly display an intrinsic defect in the production of IL-10 in response to lithium chloride. |date=11.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23988651 |full-text-url=https://sci-hub.do/10.1016/j.exger.2013.08.006 }} * {{medline-title |title=Hypothalamic neuronal toll-like receptor 2 protects against age-induced obesity. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23409245 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570778 }} * {{medline-title |title=Reduced neutrophil chemotaxis and infiltration contributes to delayed resolution of cutaneous wound infection with advanced age. |date=15.02.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23319733 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563860 }}
Описание изменений:
Пожалуйста, учтите, что любой ваш вклад в проект «hpluswiki» может быть отредактирован или удалён другими участниками. Если вы не хотите, чтобы кто-либо изменял ваши тексты, не помещайте их сюда.
Вы также подтверждаете, что являетесь автором вносимых дополнений, или скопировали их из источника, допускающего свободное распространение и изменение своего содержимого (см.
Hpluswiki:Авторские права
).
НЕ РАЗМЕЩАЙТЕ БЕЗ РАЗРЕШЕНИЯ ОХРАНЯЕМЫЕ АВТОРСКИМ ПРАВОМ МАТЕРИАЛЫ!
Отменить
Справка по редактированию
(в новом окне)
Шаблон, используемый на этой странице:
Шаблон:Medline-title
(
править
)
Навигация
Персональные инструменты
Вы не представились системе
Обсуждение
Вклад
Создать учётную запись
Войти
Пространства имён
Статья
Обсуждение
русский
Просмотры
Читать
Править
История
Ещё
Навигация
Начало
Свежие правки
Случайная страница
Инструменты
Ссылки сюда
Связанные правки
Служебные страницы
Сведения о странице
Дополнительно
Как редактировать
Вики-разметка
Telegram
Вконтакте
backup