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Aging genes 20-29
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__NOTOC__ * [[Aging genes 300|Genes with 300 and more publications]] * [[Aging genes 200-299|Genes with 200-299 publications]] * [[Aging genes 100-199|Genes with 100-199 publications]] * [[Aging genes 90-99|Genes with 90-99 publications]] * [[Aging genes 80-89|Genes with 80-89 publications]] * [[Aging genes 70-79|Genes with 70-79 publications]] * [[Aging genes 60-69|Genes with 60-69 publications]] * [[Aging genes 50-59|Genes with 50-59 publications]] * [[Aging genes 40-49|Genes with 40-49 publications]] * [[Aging genes 30-39|Genes with 30-39 publications]] * [[Aging genes 20-29|Genes with 20-29 publications]] * [[Aging genes 10-19|Genes with 10-19 publications]] * [[Aging genes 5-9|Genes with 5-9 publications]] * [[Aging genes 3-4|Genes with 3-4 publications]] * [[Aging genes 1-2|Genes with 1-2 publications]] * [[Aging_genes_A-Z_table]] ==APC== * {{medline-title |title=Differences between blacks and whites in well-being, beliefs, emotional states, behaviors and survival, 1978-2014. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32925952 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489510 }} * {{medline-title |title=Wnt-induced, TRP53-mediated Cell Cycle Arrest of Precursors Underlies Interstitial Cell of Cajal Depletion During Aging. |date=07.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32771388 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672319 }} * {{medline-title |title=Burden of musculoskeletal disorders in Iran during 1990-2017: estimates from the Global Burden of Disease Study 2017. |date=10.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32651719 |full-text-url=https://sci-hub.do/10.1007/s11657-020-00767-8 }} * {{medline-title |title=Fall-related mortality trends in older Japanese adults aged ≥65 years: a nationwide observational study. |date=11.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31831549 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924807 }} * {{medline-title |title=Stroke Mortality Rates and Trends in Romania, 1994-2017. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31624036 |full-text-url=https://sci-hub.do/10.1016/j.jstrokecerebrovasdis.2019.104431 }} * {{medline-title |title=A new approach to quantifying the EEG during walking: Initial evidence of gait related potentials and their changes with aging and dual tasking. |date=15.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31449852 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110709 }} * {{medline-title |title=Risk-period-cohort approach for averting identification problems in longitudinal models. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31291339 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620014 }} * {{medline-title |title=Wnt Signaling Mediates the Aging-Induced Differentiation Impairment of Intestinal Stem Cells. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30790135 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534527 }} * {{medline-title |title=Biased estimation of trends in cohort effects: the problems with age-period-cohort models in ecology. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30347112 |full-text-url=https://sci-hub.do/10.1002/ecy.2545 }} * {{medline-title |title=[Gender Differences in Projected Life Expectancy in Japan (2023-2047) Determined by Bayesian Age-Period-Cohort Analysis]. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30270302 |full-text-url=https://sci-hub.do/10.1265/jjh.73.338 }} * {{medline-title |title=Activated Yes-Associated Protein Accelerates Cell Cycle, Inhibits Apoptosis, and Delays Senescence in Human Periodontal Ligament Stem Cells. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30123063 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097269 }} * {{medline-title |title=Activating the Anaphase Promoting Complex to Enhance Genomic Stability and Prolong Lifespan. |date=27.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29954095 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073722 }} * {{medline-title |title=Effect of senescence marker protein 30 on the proliferation and apoptosis of human lens epithelial cells SRA01/04. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29675370 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902356 }} * {{medline-title |title=[Role and alterations of DNA methylation during the aging and cancer]. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647 |full-text-url=https://sci-hub.do/10.1556/650.2018.30927 }} * {{medline-title |title=MicroRNA-210-mediated proliferation, survival, and angiogenesis promote cardiac repair post myocardial infarction in rodents. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28948298 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941944 }} * {{medline-title |title=IL-6 Production by TLR-Activated [[APC]] Broadly Enhances Aged Cognate [[CD4]] Helper and B Cell Antibody Responses In Vivo. |date=01.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28250157 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360529 }} * {{medline-title |title=Standard expected years of life lost due to tuberculosis in Poland. |date=01.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28234085 |full-text-url=https://sci-hub.do/10.5588/ijtld.16.0268 }} * {{medline-title |title=The effects of New York City's coordinated public health programmes on mortality through 2011. |date=01.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28031310 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251557 }} * {{medline-title |title=Regional variation in coronary heart disease mortality trends in Portugal, 1981-2012. |date=01.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27665398 |full-text-url=https://sci-hub.do/10.1016/j.ijcard.2016.09.059 }} * {{medline-title |title=Mitotic degradation of yeast Fkh1 by the Anaphase Promoting Complex is required for normal longevity, genomic stability and stress resistance. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27099939 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925830 }} * {{medline-title |title=Breast Cancer Trend in Iran from 2000 to 2009 and Prediction till 2020 using a Trend Analysis Method. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27039796 |full-text-url=https://sci-hub.do/10.7314/apjcp.2016.17.3.1493 }} * {{medline-title |title=Secular trend analysis of lung cancer incidence in Sihui city, China between 1987 and 2011. |date=31.07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26227634 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593355 }} * {{medline-title |title=Black-white disparity in disability among U.S. older adults: age, period, and cohort trends. |date=09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24986183 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189652 }} * {{medline-title |title=Conserved mechanisms of tumorigenesis in the Drosophila adult midgut. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24516653 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916428 }} * {{medline-title |title=[[CD4]] T cell defects in the aged: causes, consequences and strategies to circumvent. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24440384 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989398 }} * {{medline-title |title=The anaphase promoting complex regulates yeast lifespan and rDNA stability by targeting Fob1 for degradation. |date=03.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24361936 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948801 }} * {{medline-title |title=Trends of premature mortality in Swietokrzyskie Province (Poland), years 2002-2010. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24325087 }} * {{medline-title |title=Age-related methylation patterning of housekeeping genes and tissue-specific genes is distinct between the stomach antrum and body. |date=06.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23750644 |full-text-url=https://sci-hub.do/10.2217/epi.13.17 }} * {{medline-title |title=Aging of the population may not lead to an increase in the numbers of acute coronary events: a community surveillance study and modelled forecast of the future. |date=07.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23598542 |full-text-url=https://sci-hub.do/10.1136/heartjnl-2012-303216 }} ==DDT== * {{medline-title |title=Prognostic Value of a Test of Central Auditory Function in Conversion from Mild Cognitive Impairment to Dementia. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32388503 |full-text-url=https://sci-hub.do/10.1159/000506621 }} * {{medline-title |title=Uptake kinetics of four hydrophobic organic pollutants in the earthworm Eisenia andrei in aged laboratory-contaminated natural soils. |date=01.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32061977 |full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2020.110317 }} * {{medline-title |title=Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish. |date=03-04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31911208 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061078 }} * {{medline-title |title=Second generation effects of larval metal pollutant exposure on reproduction, longevity and insecticide tolerance in the major malaria vector Anopheles arabiensis (Diptera: Culicidae). |date=07.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31910892 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947826 }} * {{medline-title |title=Protective effect of Pedro-Ximénez must against p,p'-DDE-induced liver damages in aged Mus spretus mice. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31765701 |full-text-url=https://sci-hub.do/10.1016/j.fct.2019.110984 }} * {{medline-title |title=Effects of inorganic fertilizer on larval development, adult longevity and insecticide susceptibility in the malaria vector Anopheles arabiensis (Diptera: Culicidae). |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31713993 |full-text-url=https://sci-hub.do/10.1002/ps.5676 }} * {{medline-title |title=Low-dose endosulfan inhibits proliferation and induces senescence and pro-inflammatory cytokine production in human lymphocytes, preferentially impacting cytotoxic cells. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31589084 |full-text-url=https://sci-hub.do/10.1080/1547691X.2019.1668513 }} * {{medline-title |title=DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy. |date=22.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31251805 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698745 }} * {{medline-title |title=The contribution of gut bacteria to insecticide resistance and the life histories of the major malaria vector Anopheles arabiensis (Diptera: Culicidae). |date=24.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31235803 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591418 }} * {{medline-title |title=Exposure to the insecticide-treated bednet PermaNet 2.0 reduces the longevity of the wild African malaria vector Anopheles funestus but GSTe2-resistant mosquitoes live longer. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30870507 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417719 }} * {{medline-title |title=The occurrence and dynamics of polychlorinated hydrocarbons in roe deer ([i]Capreolus capreolus[/i]) in South-western Slovakia. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30729857 |full-text-url=https://sci-hub.do/10.1080/10934529.2019.1574152 }} * {{medline-title |title=Insecticide resistance status of three vectors of Japanese encephalitis in east central India. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30565276 |full-text-url=https://sci-hub.do/10.1111/mve.12352 }} * {{medline-title |title=Effect of aging on bioaccessibility of [[DDT]]s and PCBs in marine sediment. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30471469 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349416 }} * {{medline-title |title=The effect of commercial herbicide exposure on the life history and insecticide resistance phenotypes of the major malaria vector Anopheles arabiensis (Diptera: culicidae). |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30179608 |full-text-url=https://sci-hub.do/10.1016/j.actatropica.2018.08.030 }} * {{medline-title |title=Is Chronic Exposure to Low-Dose Organochlorine Pesticides a New Risk Factor of T-cell Immunosenescence? |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29991517 |full-text-url=https://sci-hub.do/10.1158/1055-9965.EPI-17-0799 }} * {{medline-title |title=The influence of age on insecticide susceptibility of Anopheles arabiensis during dry and rainy seasons in rice irrigation schemes of Northern Tanzania. |date=11.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28893240 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594483 }} * {{medline-title |title=DNA damage tolerance in hematopoietic stem and progenitor cells in mice. |date=15.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28761001 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565453 }} * {{medline-title |title=The effects of ingestion of hormonal host factors on the longevity and insecticide resistance phenotype of the major malaria vector Anopheles arabiensis (Diptera: Culicidae). |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28700639 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507448 }} * {{medline-title |title=Bioavailability of five hydrophobic organic compounds to earthworms from sterile and non-sterile artificial soils. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28371706 |full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.03.117 }} * {{medline-title |title=The effect of elevated temperatures on the life history and insecticide resistance phenotype of the major malaria vector Anopheles arabiensis (Diptera: Culicidae). |date=14.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28193292 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307775 }} * {{medline-title |title=Dichotic Digits Test Performance Across the Ages: Results From Two Large Epidemiologic Cohort Studies. |date=05-06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27941404 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404957 }} * {{medline-title |title=The Role of Oxidative Stress in the Longevity and Insecticide Resistance Phenotype of the Major Malaria Vectors Anopheles arabiensis and Anopheles funestus. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26964046 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786153 }} * {{medline-title |title=Nuclear hormone receptor DHR96 mediates the resistance to xenobiotics but not the increased lifespan of insulin-mutant Drosophila. |date=02.02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26787908 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747718 }} * {{medline-title |title=Influence of feeding and earthworm density on compound bioaccumulation in earthworms Eisenia andrei. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26378968 |full-text-url=https://sci-hub.do/10.1016/j.envpol.2015.09.025 }} * {{medline-title |title=Greater cognitive decline with aging among elders with high serum concentrations of organochlorine pesticides. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26107947 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480979 }} * {{medline-title |title=The effect of multiple blood-feeding on the longevity and insecticide resistant phenotype in the major malaria vector Anopheles arabiensis (Diptera: Culicidae). |date=23.08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25150975 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161849 }} * {{medline-title |title=The role of canine distemper virus and persistent organic pollutants in mortality patterns of Caspian seals (Pusa caspica). |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24987857 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079250 }} * {{medline-title |title=Solid phase microextraction of organic pollutants from natural and artificial soils and comparison with bioaccumulation in earthworms. |date=02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24433790 |full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2013.11.011 }} * {{medline-title |title=Concentrations and potential health hazards of organochlorine pesticides in (shallow) groundwater of Taihu Lake region, China. |date=01.02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24239826 |full-text-url=https://sci-hub.do/10.1016/j.scitotenv.2013.10.056 }} ==GHR== * {{medline-title |title=Tissue-Specific [[GHR]] Knockout Mice: An Updated Review. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33162937 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581730 }} * {{medline-title |title=Data mining of human plasma proteins generates a multitude of highly predictive aging clocks that reflect different aspects of aging. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33031577 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681068 }} * {{medline-title |title=Muscle-dependent regulation of adipose tissue function in long-lived growth hormone-mutant mice. |date=28.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32464603 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288969 }} * {{medline-title |title=The mir-465 family is upregulated with age and attenuates growth hormone signaling in mouse liver. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637918 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413667 }} * {{medline-title |title=Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30503129 |full-text-url=https://sci-hub.do/10.1016/j.fertnstert.2018.08.018 }} * {{medline-title |title=Effects of rapamycin on growth hormone receptor knockout mice. |date=13.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29378959 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816183 }} * {{medline-title |title=Disruption of the GH receptor gene in adult mice and in insulin sensitive tissues. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29198419 |full-text-url=https://sci-hub.do/10.1016/j.ghir.2017.11.003 }} * {{medline-title |title=The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28630896 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473676 }} * {{medline-title |title=Differential effects of early-life nutrient restriction in long-lived [[GHR]]-KO and normal mice. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28523599 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505892 }} * {{medline-title |title=Brain Structure and Function Associated with Younger Adults in Growth Hormone Receptor-Deficient Humans. |date=15.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28073935 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320603 }} * {{medline-title |title=Enhanced Cognition and Hypoglutamatergic Signaling in a Growth Hormone Receptor Knockout Mouse Model of Successful Aging. |date=01.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27208894 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410893 }} * {{medline-title |title=Growth hormone receptor expression in human gluteal versus abdominal subcutaneous adipose tissue: Association with body shape. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27015877 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084456 }} * {{medline-title |title=The somatotropic axis and aging: Benefits of endocrine defects. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26925766 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792645 }} * {{medline-title |title=Growth factors, aging and age-related diseases. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26883276 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455771 }} * {{medline-title |title=Correlation Analysis Between Expression Levels of Hepatic Growth Hormone Receptor, Janus Kinase 2, Insulin-Like Growth Factor-I Genes and Dwarfism Phenotype in Bama Minipig. |date=02.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26353733 |full-text-url=https://sci-hub.do/10.1166/jnn.2015.9001 }} * {{medline-title |title=Growth hormone modulates hypothalamic inflammation in long-lived pituitary dwarf mice. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26268661 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693470 }} * {{medline-title |title=Removal of growth hormone receptor ([[GHR]]) in muscle of male mice replicates some of the health benefits seen in global [[GHR]]-/- mice. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26233957 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543039 }} * {{medline-title |title=Gene expression of key regulators of mitochondrial biogenesis is sex dependent in mice with growth hormone receptor deletion in liver. |date=03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25855408 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394730 }} * {{medline-title |title=Interaction of growth hormone receptor/binding protein gene disruption and caloric restriction for insulin sensitivity and attenuated aging. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25789159 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358413 }} * {{medline-title |title=Inflammatory and Glutamatergic Homeostasis Are Involved in Successful Aging. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25711529 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864157 }} * {{medline-title |title=Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted ([[GHR]]-KO) mice attenuates phenotypic features of slow aging. |date=12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25244225 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326932 }} * {{medline-title |title=Molecular evolution of growth hormone and insulin-like growth factor 1 receptors in long-lived, small-bodied mammals. |date=10.10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25065922 |full-text-url=https://sci-hub.do/10.1016/j.gene.2014.07.061 }} * {{medline-title |title=Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population. |date=04.03.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24606898 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988204 }} * {{medline-title |title=Expression of apoptosis-related genes in liver-specific growth hormone receptor gene-disrupted mice is sex dependent. |date=01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24550353 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296163 }} * {{medline-title |title=Direct and indirect effects of growth hormone receptor ablation on liver expression of xenobiotic metabolizing genes. |date=15.10.2013 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in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis. |date=30.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30910981 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500153 }} * {{medline-title |title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014 }} * {{medline-title |title=Isolation, Characterization, and Differentiation of Cardiac Stem Cells from the Adult Mouse Heart. |date=07.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30663680 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207148 }} * {{medline-title |title=A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation. |date=02.10.2018 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decreases [[SOX2]]-[[SOX9]] mediated glioma stem cell activity and temozolomide resistance. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26878385 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898154 }} * {{medline-title |title=Disentangling the aneuploidy and senescence paradoxes: a study of triploid breast cancers non-responsive to neoadjuvant therapy. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26860864 |full-text-url=https://sci-hub.do/10.1007/s00418-016-1415-x }} * {{medline-title |title=Role of stress-activated OCT4A in the cell fate decisions of embryonal carcinoma cells treated with etoposide. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26102294 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825594 }} * {{medline-title |title=Critical role of the miR-200 family in regulating differentiation and proliferation of neurons. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25753155 |full-text-url=https://sci-hub.do/10.1111/jnc.13089 }} * {{medline-title |title=Localization of juxtacrine factor ephrin-B2 in pituitary stem/progenitor cell niches throughout life. |date=03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25480420 |full-text-url=https://sci-hub.do/10.1007/s00441-014-2054-y }} * {{medline-title |title=No evidence for neo-oogenesis may link to ovarian senescence in adult monkey. |date=11.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23897655 |full-text-url=https://sci-hub.do/10.1002/stem.1480 }} ==VDR== * {{medline-title |title=Astragalus improve aging bone marrow mesenchymal stem cells (BMSCs) vitality and osteogenesis through VD-[[FGF23]]-Klotho axis. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32355520 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191145 }} * {{medline-title |title=25-Hydroxyvitamin D positively regulates periodontal inflammaging via [[SOCS3]]/STAT signaling in diabetic mice. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31917967 |full-text-url=https://sci-hub.do/10.1016/j.steroids.2019.108570 }} * {{medline-title |title=1,25-Dihydroxyvitamin D protects against age-related osteoporosis by a novel [[VDR]]-Ezh2-p16 signal axis. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31880094 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996957 }} * {{medline-title |title=Active vitamin D impedes the progression of non-alcoholic fatty liver disease by inhibiting cell senescence in a rat model. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31810868 |full-text-url=https://sci-hub.do/10.1016/j.clinre.2019.10.007 }} * {{medline-title |title=Vitamin D3 regulates apoptosis and proliferation in the testis of D-galactose-induced aged rat model. |date=01.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31575929 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773724 }} * {{medline-title |title=Age-dependent expression of the vitamin D receptor and the protective effect of vitamin D receptor activation on H O -induced apoptosis in rat intervertebral disc cells. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30905826 |full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2019.03.013 }} * {{medline-title |title=Vitamin D Receptor in Muscle Atrophy of Elderly Patients: A Key Element of Osteoporosis-Sarcopenia Connection. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574409 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284754 }} * {{medline-title |title=Reduced vitamin D receptor ([[VDR]]) expression and plasma vitamin D levels are associated with aging-related prostate lesions. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29508414 |full-text-url=https://sci-hub.do/10.1002/pros.23498 }} * {{medline-title |title=[[VDR]] Activation Reduces Proteinuria and High-Glucose-Induced Injury of Kidneys and Podocytes by Regulating Wnt Signaling Pathway. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28848172 |full-text-url=https://sci-hub.do/10.1159/000480315 }} * {{medline-title |title=Vitamin D and the brain: Genomic and non-genomic actions. |date=15.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28579120 |full-text-url=https://sci-hub.do/10.1016/j.mce.2017.05.035 }} * {{medline-title |title=Targeted next generation sequencing of the entire vitamin D receptor gene reveals polymorphisms correlated with vitamin D deficiency among older Filipino women with and without fragility fracture. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28068558 |full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2016.12.003 }} * {{medline-title |title=Using Hyperpolarized Xe MRI to Quantify the Pulmonary Ventilation Distribution. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27617823 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411263 }} * {{medline-title |title=Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27584680 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008632 }} * {{medline-title |title=Relationship between cardiometabolic profile, vitamin D status and BsmI polymorphism of the [[VDR]] gene in non-institutionalized elderly subjects: Cardiometabolic profile, vitamin D status and BsmI polymorphism of the [[VDR]] gene in non-institutionalized elderly subjects. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27125758 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.04.020 }} * {{medline-title |title=Impact of vitamin D receptor polymorphisms in centenarians. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26956844 |full-text-url=https://sci-hub.do/10.1007/s12020-016-0908-7 }} * {{medline-title |title=Aging and a long-term diabetes mellitus increase expression of 1 α-hydroxylase and vitamin D receptors in the rat liver. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26471398 |full-text-url=https://sci-hub.do/10.1016/j.exger.2015.10.005 }} * {{medline-title |title=Nuclear hormone receptors: Roles of xenobiotic detoxification and sterol homeostasis in healthy aging. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26383043 |full-text-url=https://sci-hub.do/10.3109/10409238.2015.1067186 }} * {{medline-title |title=Vitamin D Receptor Ablation and Vitamin D Deficiency Result in Reduced Grip Strength, Altered Muscle Fibers, and Increased Myostatin in Mice. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26340892 |full-text-url=https://sci-hub.do/10.1007/s00223-015-0054-x }} * {{medline-title |title=Extra-intestinal calcium handling contributes to normal serum calcium levels when intestinal calcium absorption is suboptimal. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26319498 |full-text-url=https://sci-hub.do/10.1016/j.bone.2015.08.023 }} * {{medline-title |title=Vitamin D Receptor Genotype Modulates the Correlation between Vitamin D and Circulating Levels of let-7a/b and Vitamin D Intake in an Elderly Cohort. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25969372 |full-text-url=https://sci-hub.do/10.1159/000381676 }} * {{medline-title |title=Vitamin D, muscle and bone: Integrating effects in development, aging and injury. |date=15.07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25837735 |full-text-url=https://sci-hub.do/10.1016/j.mce.2015.03.020 }} * {{medline-title |title=Association between vitamin D concentration and levels of sex hormones in an elderly Polish population with different genotypes of [[VDR]] polymorphisms (rs10735810, rs1544410, rs7975232, rs731236). |date=15.03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25595352 |full-text-url=https://sci-hub.do/10.1016/j.gene.2015.01.022 }} * {{medline-title |title=Effect modification by vitamin D receptor genetic polymorphisms in the association between cumulative lead exposure and pulse pressure: a longitudinal study. |date=13.01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25582168 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417283 }} * {{medline-title |title=Vitamin D receptor and megalin gene polymorphisms are associated with central adiposity status and changes among US adults. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25191583 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153078 }} * {{medline-title |title=Vitamin D signaling in myogenesis: potential for treatment of sarcopenia. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25197630 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147791 }} * {{medline-title |title=A randomized study on the effect of vitamin D₃ supplementation on skeletal muscle morphology and vitamin D receptor concentration in older women. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24108316 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849671 }} * {{medline-title |title=Impact of vitamin D receptor [[VDR]] rs2228570 polymorphism in oldest old. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24060611 |full-text-url=https://sci-hub.do/10.1159/000350159 }} * {{medline-title |title=Characterization of the testicular, epididymal and endocrine phenotypes in the Leuven Vdr-deficient mouse model: targeting estrogen signalling. |date=05.09.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23850520 |full-text-url=https://sci-hub.do/10.1016/j.mce.2013.06.036 }} * {{medline-title |title=Association of vitamin D receptor with longevity and healthy aging. |date=07.05.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23690102 }} ==ACE2== * {{medline-title |title=How Does SARS-CoV-2 Affect the Central Nervous System? A Working Hypothesis. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33304284 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701095 }} * {{medline-title |title=[[ACE]]2/[[ACE]] imbalance and impaired vasoreparative functions of stem/progenitor cells in aging. |date=27.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33247425 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694587 }} * {{medline-title |title=[[ACE2]]/[[ADAM17]]/[[TMPRSS2]] Interplay May Be the Main Risk Factor for COVID-19. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33117379 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575774 }} * {{medline-title |title=Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33112891 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592753 }} * {{medline-title |title=COVID-19 is an emergent disease of aging. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33006233 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576244 }} * {{medline-title |title=Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 [[ACE2]]-[[TMPRSS2]]-Furin-[[DPP4]] Axis. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013423 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510459 }} * {{medline-title |title=Susceptibility to COVID-19 in populations with health disparities: Posited involvement of mitochondrial disorder, socioeconomic stress, and pollutants. |date=09.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32905655 |full-text-url=https://sci-hub.do/10.1002/jbt.22626 }} * {{medline-title |title=A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32854108 |full-text-url=https://sci-hub.do/10.1038/s41586-020-2708-8 }} * {{medline-title |title=Coronavirus Disease-2019 Conundrum: RAS Blockade and Geriatric-Associated Neuropsychiatric Disorders. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850927 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431869 }} * {{medline-title |title=COVID-19 and Senotherapeutics: Any Role for the Naturally-occurring Dipeptide Carnosine? |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32765939 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390525 }} * {{medline-title |title=The dual impact of [[ACE2]] in COVID-19 and ironical actions in geriatrics and pediatrics with possible therapeutic solutions. |date=15.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32653522 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347488 }} * {{medline-title |title=The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the 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|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232010 }} * {{medline-title |title=Restoration of the Renin-Angiotensin System Balance Is a Part of the Effect of Fasting on Cardiovascular Rejuvenation: Role of Age and Fasting Models. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31571520 |full-text-url=https://sci-hub.do/10.1089/rej.2019.2254 }} * {{medline-title |title=Angiotensin 1-7 alleviates aging-associated muscle weakness and bone loss, but is not associated with accelerated aging in [[ACE2]]-knockout mice. |date=30.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31519791 |full-text-url=https://sci-hub.do/10.1042/CS20190573 }} * {{medline-title |title=Age-dependent differences in pulmonary host responses in ARDS: a prospective observational cohort study. |date=14.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31089908 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517452 }} * {{medline-title |title=The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29407880 |full-text-url=https://sci-hub.do/10.1016/j.atherosclerosis.2018.01.043 }} * {{medline-title |title=Sex differences in the aging pattern of renin-angiotensin system serum peptidases. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28174624 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291971 }} * {{medline-title |title=Chymase-dependent production of angiotensin II: an old enzyme in old hearts. |date=01.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27815252 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336578 }} * {{medline-title |title=Age-Associated Changes in the Vascular Renin-Angiotensin System in Mice. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27200147 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855022 }} * {{medline-title |title=Angiotensin converting enzyme 2/Ang-(1-7)/mas axis protects brain from ischemic injury with a tendency of age-dependence. |date=05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24581232 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840841 }} * {{medline-title |title=Necessity of angiotensin-converting enzyme-related gene for cardiac functions and longevity of Drosophila melanogaster assessed by optical coherence tomography. |date=01.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24002232 |full-text-url=https://sci-hub.do/10.1117/1.JBO.19.1.011014 }} ==AFM== * {{medline-title |title=Photocatalytic aging process of Nano-TiO coated polypropylene microplastics: Combining atomic force microscopy and infrared spectroscopy ([[AFM]]-IR) for nanoscale chemical characterization. |date=15.02.2021 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33080556 |full-text-url=https://sci-hub.do/10.1016/j.jhazmat.2020.124159 }} * {{medline-title |title=Nanoscale infrared, thermal and mechanical properties of aged 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Between miR-148a and [[DNMT1]] Might be Exploited for Pancreatic Cancer Therapy. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25950085 |full-text-url=https://sci-hub.do/10.3109/07357907.2015.1025794 }} * {{medline-title |title=Expression of DNA methyltransferases is influenced by growth hormone in the long-living Ames dwarf mouse in vivo and in vitro. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24201695 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111294 }} ==ELOVL2== * {{medline-title |title=[[ELOVL2]]: Not just a biomarker of aging. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33043173 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544151 }} * {{medline-title |title=Age prediction in living: Forensic epigenetic age estimation based on blood samples. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32721866 |full-text-url=https://sci-hub.do/10.1016/j.legalmed.2020.101763 }} * {{medline-title |title=The lipid elongation enzyme [[ELOVL2]] is a molecular regulator of aging in the retina. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31943697 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996962 }} * {{medline-title |title=Age Estimation Based on DNA Methylation Using Blood Samples From Deceased Individuals. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31490551 |full-text-url=https://sci-hub.do/10.1111/1556-4029.14185 }} * {{medline-title |title=Human aging DNA methylation signatures are conserved but accelerated in cultured fibroblasts. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156022 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691995 }} * {{medline-title |title=Cell and tissue type independent age-associated DNA methylation changes are not rare but common. |date=27.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30482885 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286821 }} * {{medline-title |title=DNA methylation of the [[ELOVL2]], [[FHL2]], [[KLF14]], C1orf132/MIR29B2C, and [[TRIM59]] genes for age prediction from blood, saliva, and buccal swab samples. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30300865 |full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.09.010 }} * {{medline-title |title=Proof of concept study of age-dependent DNA methylation markers across different tissues by massive parallel sequencing. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30031222 |full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.07.007 }} * {{medline-title |title=Age-related DNA methylation changes are tissue-specific with [[ELOVL2]] promoter methylation as exception. |date=30.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29848354 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975493 }} * {{medline-title |title=DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived 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blood and teeth samples using a selected set of DNA methylation markers. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26280308 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844214 }} * {{medline-title |title=Development of a forensically useful age prediction method based on DNA methylation analysis. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26026729 |full-text-url=https://sci-hub.do/10.1016/j.fsigen.2015.05.001 }} * {{medline-title |title=Genome-wide age-related changes in DNA methylation and gene expression in human PBMCs. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24789080 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082572 }} ==GSC== * {{medline-title |title=[i]mastermind[/i] regulates niche ageing independently of the [i]Notch[/i] pathway in the [i]Drosophila[/i] ovary. |date=29.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31744422 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893403 }} * {{medline-title |title=Germline stem cell homeostasis. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31155359 |full-text-url=https://sci-hub.do/10.1016/bs.ctdb.2019.04.006 }} * {{medline-title |title=Endocrine regulation of female germline stem cells in the fruit fly Drosophila melanogaster. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31109668 |full-text-url=https://sci-hub.do/10.1016/j.cois.2018.07.001 }} * {{medline-title |title=Generation of Inducible Gene-Switched GAL4 Expressed in the [i]Drosophila[/i] Female Germline Stem Cell Niche. |date=05.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31018943 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553524 }} * {{medline-title |title=YAP/Yorkie in the germline modulates the age-related decline of germline stem cells and niche cells. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30943201 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447158 }} * {{medline-title |title=Diminished Jak/STAT Signaling Causes Early-Onset Aging Defects in Stem Cell Cytokinesis. |date=21.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30612906 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783278 }} * {{medline-title |title=JNK signaling triggers spermatogonial dedifferentiation during chronic stress to maintain the germline stem cell pool in the [i]Drosophila[/i] testis. |date=09.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29985130 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070334 }} * {{medline-title |title=Age-related differences in BOLD modulation to cognitive control costs in a multitasking paradigm: Global switch, local switch, and compatibility-switch costs. |date=15.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29414492 |full-text-url=https://sci-hub.do/10.1016/j.neuroimage.2018.01.030 }} * {{medline-title |title=Modelling glioblastoma tumour-host cell interactions using adult brain organotypic slice 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|title=Suberoylanilide hydroxamic acid represses glioma stem-like cells. |date=18.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27863490 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116136 }} * {{medline-title |title=Flavonoids and darkness lower PCD in senescing Vitis vinifera suspension cell cultures. |date=26.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27782806 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080730 }} * {{medline-title |title=DNA damage-induced Lok/CHK2 activation compromises germline stem cell self-renewal and lineage differentiation. |date=01.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27729408 |full-text-url=https://sci-hub.do/10.1242/dev.141069 }} * {{medline-title |title=The Wnt pathway limits BMP signaling outside of the germline stem cell niche in Drosophila ovaries. |date=01.09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27364467 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001506 }} * {{medline-title |title=Nuclear hormone receptors as mediators of metabolic adaptability following reproductive perturbations. |date=01-03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27073739 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805359 }} * {{medline-title |title=Senescence from glioma stem cell differentiation promotes tumor growth. |date=05.02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26775840 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176357 }} * {{medline-title |title=Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence. |date=24.08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26196144 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541496 }} * {{medline-title |title=Notch signaling mediates the age-associated decrease in adhesion of germline stem cells to the niche. |date=12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25521289 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|title=Self-Report Tools for Assessing Physical Activity in Community-Living Older Adults with Multiple Chronic Conditions: A Systematic Review of Psychometric Properties and Feasibility. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31631827 |full-text-url=https://sci-hub.do/10.1017/S0714980819000357 }} * {{medline-title |title=Burden on Caregivers of Adults with Multiple Chronic Conditions: Intersectionality of Age, Gender, Education level, Employment Status, and Impact on Social Life. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31475644 |full-text-url=https://sci-hub.do/10.1017/S071498081900045X }} * {{medline-title |title=Using the Technology Acceptance Model to Explore User Experience, Intent to Use, and Use Behavior of a Patient Portal Among Older Adults With Multiple Chronic Conditions: Descriptive Qualitative Study. |date=08.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30958272 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475817 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|title=Tet2-mediated clonal hematopoiesis in nonconditioned mice accelerates age-associated cardiac dysfunction. |date=26.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32154790 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213793 }} * {{medline-title |title=Inflammation and Ectopic Fat Deposition in the Aging Murine Liver Is Influenced by [[CCR2]]. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31843499 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013280 }} * {{medline-title |title=Klotho-mediated targeting of [[CCL2]] suppresses the induction of colorectal cancer progression by stromal cell senescent microenvironments. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31545552 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822285 }} * {{medline-title |title=Aging induces cardiac mesenchymal stromal cell senescence and promotes endothelial cell fate of the CD90 subset. |date=10.2019 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Examining the WHO ICF disability domains as mediators of this relationship. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25209970 |full-text-url=https://sci-hub.do/10.1080/13607863.2014.955457 }} * {{medline-title |title=Differential trajectories of well-being in older adult women: the role of optimism. |date=11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25209994 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483851 }} * {{medline-title |title=Validation of an instrument to evaluate quality of life in the aging population: WHOQOL-AGE. |date=23.10.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24152691 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015924 }} * {{medline-title |title=Rare variants in [[CFI]], [[C3]] and [[C9]] are associated with high risk of advanced age-related macular degeneration. |date=11.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24036952 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902040 }} * {{medline-title |title=Vascular depression and frailty: a compound threat to longevity among older-old women. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23683113 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148075 }} ==DNMT3A== * {{medline-title |title=Aging and leukemic evolution of hematopoietic stem cells under various stress conditions. |date=05.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33292805 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643313 }} * {{medline-title |title=Epigenetic regulation of miR-29a/miR-30c/[[DNMT3A]] axis controls [[SOD2]] and mitochondrial oxidative stress in human mesenchymal stem cells. |date=09.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32961441 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509080 }} * {{medline-title |title=60 Years of clonal hematopoiesis research: From X-chromosome inactivation studies to the identification of driver mutations. |date=03.2020 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|date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883022 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125185 }} * {{medline-title |title=Effects of Parental Aging During Embryo Development and Adult Life: The Case of Nothobranchius furzeri. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304310 |full-text-url=https://sci-hub.do/10.1089/zeb.2017.1494 }} * {{medline-title |title=Genetic Biomarkers on Age-Related Cognitive Decline. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307 }} * {{medline-title |title=An inflammatory environment containing TNFα favors Tet2-mutant clonal hematopoiesis. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29195897 |full-text-url=https://sci-hub.do/10.1016/j.exphem.2017.11.002 }} * {{medline-title |title=Sequential acquisition of mutations in myelodysplastic syndromes. |date=2017 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recruited to persistent DNA damage lesions in an [[RNF168]]-53BP1 dependent manner and contribute to DNA repair. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31009828 |full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.04.001 }} * {{medline-title |title=Nuclear Nox4 interaction with prelamin A is associated with nuclear redox control of stem cell aging. |date=24.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30362963 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224265 }} * {{medline-title |title=Aging and lymphocyte changes by immunomodulatory therapies impact [[PML]] risk in multiple sclerosis patients. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774781 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013383 }} * {{medline-title |title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes. |date=28.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404 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|full-text-url=https://sci-hub.do/10.1111/asj.12073 }} ==TET2== * {{medline-title |title=Aging and leukemic evolution of hematopoietic stem cells under various stress conditions. |date=05.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33292805 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643313 }} * {{medline-title |title=[[TET2]]-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity. |date=27.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33113366 |full-text-url=https://sci-hub.do/10.1016/j.celrep.2020.108326 }} * {{medline-title |title=Non-coding and Loss-of-Function Coding Variants in [[TET2]] are Associated with Multiple Neurodegenerative Diseases. |date=07.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32330418 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212268 }} * {{medline-title |title=Mutational spectrum and dynamics of clonal hematopoiesis in anemia of older individuals. 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