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__NOTOC__ * [[Aging genes 100|Genes with 100 and more publications]] * [[Aging genes 60-99|Genes with 60-99 publications]] * [[Aging genes 30-59|Genes with 30-59 publications]] * [[Aging genes 10-29|Genes with 10-29 publications]] * [[Aging genes 3-9|Genes with 3-9 publications]] * [[Aging genes 1-2|Genes with 1-2 publications]] ==TNF== * {{medline-title |title=Naringenin alleviates nonalcoholic steatohepatitis in middle-aged Apoe mice: role of SIRT1. |date=18.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33234364 |full-text-url=https://sci-hub.do/10.1016/j.phymed.2020.153412 }} * {{medline-title |title=Protective role of microglial HO-1 blockade in aging: Implication of iron metabolism. |date=06.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33212416 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680814 }} * {{medline-title |title=Anti-aging effect of DL-β-hydroxybutyrate against hepatic cellular senescence induced by D-galactose or γ-irradiation via autophagic flux stimulation in male rats. |date=01-02.2021 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33147533 |full-text-url=https://sci-hub.do/10.1016/j.archger.2020.104288 }} * {{medline-title |title=Exploring the extensive crosstalk between the antagonistic cytokines- TGF-β and [[TNF]]-α in regulating cancer pathogenesis. |date=03.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33153895 |full-text-url=https://sci-hub.do/10.1016/j.cyto.2020.155348 }} * {{medline-title |title=Long non-coding RNA SNHG29 regulates cell senescence via p53/p21 signaling in spontaneous preterm birth. |date=15.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33080448 |full-text-url=https://sci-hub.do/10.1016/j.placenta.2020.10.009 }} * {{medline-title |title=Cognition Is Associated With Peripheral Immune Molecules in Healthy Older Adults: A Cross-Sectional Study. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32983153 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493640 }} * {{medline-title |title=Anti-aging effects of [i]Ribes meyeri[/i] anthocyanins on neural stem cells and aging mice. |date=12.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32920547 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521483 }} * {{medline-title |title=Effects of a four week detraining period on physical, metabolic, and inflammatory profiles of elderly women who regularly participate in a program of strength training. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32863968 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450596 }} * {{medline-title |title=Contribution of Porphyromonas gingivalis lipopolysaccharide to experimental periodontitis in relation to aging. |date=26.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32851571 |full-text-url=https://sci-hub.do/10.1007/s11357-020-00258-1 }} * {{medline-title |title=New MoDC-Targeting [[TNF]] Fusion Proteins Enhance Cyclic Di-GMP Vaccine Adjuvanticity in Middle-Aged and Aged Mice. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32849581 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427090 }} * {{medline-title |title=Cognitive impairment in elderly patients with rheumatic disease and the effect of disease-modifying anti-rheumatic drugs. |date=30.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32862311 |full-text-url=https://sci-hub.do/10.1007/s10067-020-05372-1 }} * {{medline-title |title=Cotinine ameliorates memory and learning impairment in senescent mice. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32818583 |full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2020.08.010 }} * {{medline-title |title=Kynurenines link chronic inflammation to functional decline and physical frailty. |date=20.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32814718 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455140 }} * {{medline-title |title=Voluntary exercise training attenuated the middle-aged maturity-induced cardiac apoptosis. |date=15.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32781061 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118187 }} * {{medline-title |title=Preclinical Evaluation of a Food-Derived Functional Ingredient to Address Skeletal Muscle Atrophy. |date=29.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32751276 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469066 }} * {{medline-title |title=Childhood survivors of high-risk neuroblastoma show signs of immune recovery and not immunosenescence. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32744364 |full-text-url=https://sci-hub.do/10.1002/eji.202048541 }} * {{medline-title |title=FK506 induces lung lymphatic endothelial cell senescence and downregulates LYVE-1 expression, with associated decreased hyaluronan uptake. |date=31.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32736525 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395348 }} * {{medline-title |title=Late-onset hypogonadism: Reductio ad absurdum of the cardiovascular risk-benefit of testosterone replacement therapy. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32737921 |full-text-url=https://sci-hub.do/10.1111/andr.12876 }} * {{medline-title |title=Doxorubicin generates senescent microglia that exhibit altered proteomes, higher levels of cytokine secretion, and a decreased ability to internalize amyloid β. |date=15.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32738344 |full-text-url=https://sci-hub.do/10.1016/j.yexcr.2020.112203 }} * {{medline-title |title=Time restricted feeding provides a viable alternative to alternate day fasting when evaluated in terms of redox homeostasis in rats. |date=16.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32717588 |full-text-url=https://sci-hub.do/10.1016/j.archger.2020.104188 }} * {{medline-title |title=Associations Between Plasma Immunomodulatory and Inflammatory Mediators With VACS Index Scores Among Older HIV-Infected Adults on Antiretroviral Therapy. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32695109 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338430 }} * {{medline-title |title=Chrysin Impact on Oxidative and Inflammation Damages in the Liver of Aged Male Rats. |date=17.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32679027 |full-text-url=https://sci-hub.do/10.2174/1871530320666200717162304 }} * {{medline-title |title=Correction of immunosuppression in aged septic rats by human ghrelin and growth hormone through the vagus nerve-dependent inhibition of TGF-β production. |date=16.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32677895 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364485 }} * {{medline-title |title=Epigenetics of neuroinflammation: Immune response, inflammatory response and cholinergic synaptic involvement evidenced by genome-wide DNA methylation analysis of delirious inpatients. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32590150 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486988 }} * {{medline-title |title=[i]Andrographis paniculata[/i] and Its Bioactive Diterpenoids Against Inflammation and Oxidative Stress in Keratinocytes. |date=17.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32560449 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346124 }} * {{medline-title |title=Etanercept improves aging-induced cognitive deficits by reducing inflammation and vascular dysfunction in rats. |date=01.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32569601 |full-text-url=https://sci-hub.do/10.1016/j.physbeh.2020.113019 }} * {{medline-title |title=Bacterial antigen translocation and age as BMI-independent contributing factors on systemic inflammation in NAFLD patients. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32559006 |full-text-url=https://sci-hub.do/10.1111/liv.14571 }} * {{medline-title |title=Bone marrow mesenchymal stem cells improve thymus and spleen function of aging rats through affecting P21/PCNA and suppressing oxidative stress. |date=19.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32561691 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343510 }} * {{medline-title |title=Glycolic acid adjusted to pH 4 stimulates collagen production and epidermal renewal without affecting levels of proinflammatory [[TNF]]-alpha in human skin explants. |date=24.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32583600 |full-text-url=https://sci-hub.do/10.1111/jocd.13570 }} * {{medline-title |title=A20 of nucleus pulposus cells plays a self-protection role via the nuclear factor-kappa B pathway in the inflammatory microenvironment. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32566144 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284293 }} * {{medline-title |title=Age-associated decline in neural, endocrine, and immune responses in men and women: Involvement of intracellular signaling pathways. |date=15.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32563124 |full-text-url=https://sci-hub.do/10.1016/j.jneuroim.2020.577290 }} * {{medline-title |title=Classical and lectin complement pathways and markers of inflammation for investigation of susceptibility to infections among healthy older adults. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32536956 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285792 }} * {{medline-title |title=Activation of FoxO1/SIRT1/RANKL/OPG pathway may underlie the therapeutic effects of resveratrol on aging-dependent male osteoporosis. |date=12.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32532246 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293127 }} * {{medline-title |title=The senescence-associated secretome as an indicator of age and medical risk. |date=18.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32554926 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406245 }} * {{medline-title |title=Exercise Partially Rejuvenates Muscle Stem Cells. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32484032 |full-text-url=https://sci-hub.do/10.1089/rej.2020.2359 }} * {{medline-title |title=Brazilian berry extract (Myrciaria jaboticaba): A promising therapy to minimize prostatic inflammation and oxidative stress. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32460430 |full-text-url=https://sci-hub.do/10.1002/pros.24017 }} * {{medline-title |title=Potential therapeutic effects of endothelial cells trans-differentiated from Wharton's Jelly-derived mesenchymal stem cells on altered vascular functions in aged diabetic rat model. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32426041 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216374 }} * {{medline-title |title=[Effect of fragmented sleep on postoperative cognitive function and central neuroinflammation]. |date=05.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32375444 |full-text-url=https://sci-hub.do/10.3760/cma.j.cn112137-20191215-02734 }} * {{medline-title |title=Can blocking inflammation enhance immunity during aging? |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32386656 |full-text-url=https://sci-hub.do/10.1016/j.jaci.2020.03.016 }} * {{medline-title |title=[FAS- and [[TNF]]-dependent ways participation in apoptosis mechanisms in hypotalumus in physiological and pathological aging.] |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32362081 }} * {{medline-title |title=Ultrasound-guided continuous thoracic paravertebral block alleviates postoperative delirium in elderly patients undergoing esophagectomy: A randomized controlled trial. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32332664 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440095 }} * {{medline-title |title=17β-Estradiol improves insulin signalling and insulin resistance in the aged female hearts: Role of inflammatory and anti-inflammatory cytokines. |date=15.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32311377 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.117673 }} * {{medline-title |title=Synergistic Antitumor Efficacy of Magnetohyperthermia and Poly(lactic-co-glycolic acid)-Encapsulated Selol in Ehrlich Breast Adenocarcinoma Treatment in Elderly Swiss Mice. |date=01.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32252879 |full-text-url=https://sci-hub.do/10.1166/jbn.2020.2890 }} * {{medline-title |title=Pinitol suppresses [[TNF]]-α-induced chondrocyte senescence. |date=19.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32200264 |full-text-url=https://sci-hub.do/10.1016/j.cyto.2020.155047 }} * {{medline-title |title=[Aging of skin fibroblasts: genetic and epigenetic factors.] |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32160428 }} * {{medline-title |title=Functional and traditional training improve muscle power and reduce proinflammatory cytokines in older women: A randomized controlled trial. |date=01.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32151735 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110920 }} * {{medline-title |title=Associations of [[TNF]]-α -308 G>A and [[TNF]]-β 252 A>G with Physical Function and BNP-Rugao Longevity and Ageing Study. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32115620 |full-text-url=https://sci-hub.do/10.1007/s12603-020-1336-1 }} * {{medline-title |title=3D TECA hydrogel reduces cellular senescence and enhances fibroblasts migration in wound healing. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32104405 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032142 }} * {{medline-title |title=Regulatory Effect of Anwulignan on the Immune Function Through Its Antioxidation and Anti-Apoptosis in D-Galactose-Induced Aging Mice. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32099340 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996228 }} * {{medline-title |title=Pretreatment Frailty Is Independently Associated With Increased Risk of Infections After Immunosuppression in Patients With Inflammatory Bowel Diseases. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32105728 |full-text-url=https://sci-hub.do/10.1053/j.gastro.2020.02.032 }} * {{medline-title |title=The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of SIRT1. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32047577 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003265 }} * {{medline-title |title=In the Absence of a TCR Signal IL-2/IL-12/18-Stimulated γδ T Cells Demonstrate Potent Anti-Tumoral Function Through Direct Killing and Senescence Induction in Cancer Cells. |date=04.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31947966 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017313 }} * {{medline-title |title=Aging is associated with loss of beneficial effects of estrogen on leptin responsiveness in mice fed high fat diet: Role of estrogen receptor α and cytokines. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31904410 |full-text-url=https://sci-hub.do/10.1016/j.mad.2019.111198 }} * {{medline-title |title=Mitochondrial Dysfunction and Alpha-Lipoic Acid: Beneficial or Harmful in Alzheimer's Disease? |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31885820 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914903 }} * {{medline-title |title=Design, synthesis and evaluation of diosgenin carbamate derivatives as multitarget anti-Alzheimer's disease agents. |date=01.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31837501 |full-text-url=https://sci-hub.do/10.1016/j.ejmech.2019.111913 }} * {{medline-title |title=Oral Administration of Okara Soybean By-Product Attenuates Cognitive Impairment in a Mouse Model of Accelerated Aging. |date=03.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31816987 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950093 }} * {{medline-title |title=Electric vagal nerve stimulation inhibits inflammation and improves early postoperation cognitive dysfunction in aged rats. |date=23.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31759387 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875068 }} * {{medline-title |title=Metformin decreases LPS-induced inflammatory response in rabbit annulus fibrosus stem/progenitor cells by blocking HMGB1 release. |date=26.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31772144 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914423 }} * {{medline-title |title=The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling in vitro. |date=11.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31746877 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906224 }} * {{medline-title |title=Arsenic induces human chondrocyte senescence and accelerates rat articular cartilage aging. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31734849 |full-text-url=https://sci-hub.do/10.1007/s00204-019-02607-2 }} * {{medline-title |title=Bone Benefits of Fish Oil Supplementation Depend on its EPA and DHA Content. |date=08.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31717258 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893665 }} * {{medline-title |title=Inflammaging phenotype in rhesus macaques is associated with a decline in epithelial barrier-protective functions and increased pro-inflammatory function in CD161-expressing cells. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31713098 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925095 }} * {{medline-title |title=Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians. |date=26.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31719197 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883788 }} * {{medline-title |title=Gut microbiota combined with metabolomics reveals the metabolic profile of the normal aging process and the anti-aging effect of FuFang Zhenshu TiaoZhi(FTZ) in mice. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31704617 |full-text-url=https://sci-hub.do/10.1016/j.biopha.2019.109550 }} * {{medline-title |title=Intervertebral disc ageing and degeneration: The antiapoptotic effect of oestrogen. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31669486 |full-text-url=https://sci-hub.do/10.1016/j.arr.2019.100978 }} * {{medline-title |title=MicroRNA 16-5p is upregulated in calorie-restricted mice and modulates inflammatory cytokines of macrophages. |date=30.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31654705 |full-text-url=https://sci-hub.do/10.1016/j.gene.2019.144191 }} * {{medline-title |title=Aerobic exercise modulates cytokine profile and sleep quality in elderly. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31656505 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794533 }} * {{medline-title |title=Trehalose targets Nrf2 signal to alleviate d-galactose induced aging and improve behavioral ability. |date=01.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31630800 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.10.088 }} * {{medline-title |title=Anti-Inflammatory and Anti-Aging Evaluation of Pigment-Protein Complex Extracted from [i]Chlorella Pyrenoidosa[/i]. |date=16.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31623220 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836285 }} * {{medline-title |title=Inflammatory mediators and the risk of falls among older women with acute low back pain: data from Back Complaints in the Elders (BACE)-Brazil. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31606818 |full-text-url=https://sci-hub.do/10.1007/s00586-019-06168-x }} * {{medline-title |title=Acetylcholinesterase inhibitors targeting the cholinergic anti-inflammatory pathway: a new therapeutic perspective in aging-related disorders. |date=03.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31583530 |full-text-url=https://sci-hub.do/10.1007/s40520-019-01359-4 }} * {{medline-title |title=Study on Metabolic Trajectory of Liver Aging and the Effect of Fufang Zhenzhu Tiaozhi on Aging Mice. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31555127 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722462 }} * {{medline-title |title=Systemic Tumor Necrosis Factor-Alpha Trajectories Relate to Brain Health in Typically Aging Older Adults. |date=13.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31549145 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457183 }} * {{medline-title |title=Targeting senescence improves angiogenic potential of adipose-derived mesenchymal stem cells in patients with preeclampsia. |date=14.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31521202 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744626 }} * {{medline-title |title=Suppression of gut dysbiosis by Bifidobacterium longum alleviates cognitive decline in 5XFAD transgenic and aged mice. |date=14.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31413350 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694197 }} * {{medline-title |title=Moderate hyperoxia induces senescence in developing human lung fibroblasts. |date=01.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31411059 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879905 }} * {{medline-title |title=Aging-related carcinoembryonic antigen-related cell adhesion molecule 1 signaling promotes vascular dysfunction. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31389127 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826129 }} * {{medline-title |title=Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APP /PS1 Transgenic Mice. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31417357 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682662 }} * {{medline-title |title=Age- and diet-specific effects of chronic exposure to chlorpyrifos on hormones, inflammation and gut microbiota in rats. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31400786 |full-text-url=https://sci-hub.do/10.1016/j.pestbp.2019.05.018 }} * {{medline-title |title=Knockout of longevity gene Sirt1 in zebrafish leads to oxidative injury, chronic inflammation, and reduced life span. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31386694 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684063 }} * {{medline-title |title=Glycation of macrophages induces expression of pro-inflammatory cytokines and reduces phagocytic efficiency. |date=29.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31386629 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682540 }} * {{medline-title |title=Tamoxifen-induced, intestinal-specific deletion of [i]Slc5a6[/i] in adult mice leads to spontaneous inflammation: involvement of NF-κB, [[NLRP3]], and gut microbiota. |date=01.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31369292 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842991 }} * {{medline-title |title=Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms. |date=22.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31332237 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646318 }} * {{medline-title |title=Inflammatory markers and bone health in postmenopausal women: a cross-sectional overview. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31333751 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Shwartzman Reaction. |date=02.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31269748 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651521 }} * {{medline-title |title=Inflammation-related genes are associated with epigenetic aging in HIV. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31286441 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923602 }} * {{medline-title |title=Function, Oxidative, and Inflammatory Stress Parameters in Immune Cells as Predictive Markers of Lifespan throughout Aging. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31281577 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589234 }} * {{medline-title |title=The Impact of Prophylactic Lacosamide on LPS-Induced Neuroinflammation in Aged Rats. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31267274 |full-text-url=https://sci-hub.do/10.1007/s10753-019-01053-7 }} * {{medline-title |title=Impaired sleep quality is associated with concurrent elevations in inflammatory markers: are post-menopausal women at greater risk? |date=08.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31287027 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615113 }} * {{medline-title |title=Potential effects of rapeseed peptide Maillard reaction products on aging-related disorder attenuation and gut microbiota modulation in d-galactose induced aging mice. |date=17.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31265043 |full-text-url=https://sci-hub.do/10.1039/c9fo00791a }} * {{medline-title |title=Ellagic acid dose and time-dependently abrogates d-galactose-induced animal model of aging: Investigating the role of PPAR-γ. |date=01.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31238053 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116595 }} * {{medline-title |title=Lactobacillus sp. improved microbiota and metabolite profiles of aging rats. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31207344 |full-text-url=https://sci-hub.do/10.1016/j.phrs.2019.104312 }} * {{medline-title |title=Local and systemic effects of aging on acute pancreatitis. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31204259 |full-text-url=https://sci-hub.do/10.1016/j.pan.2019.06.005 }} * {{medline-title |title=Salicin prevents [[TNF]]-α-induced cellular senescence in human umbilical vein endothelial cells (HUVECs). |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31220953 |full-text-url=https://sci-hub.do/10.1080/21691401.2019.1629949 }} * {{medline-title |title=Age-related dynamics of pro-inflammatory cytokines in equine bronchoalveolar lavage (BAL) fluid and peripheral blood from horses managed on pasture. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31201919 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110634 }} * {{medline-title |title=The beneficial effects of 15 units of high-intensity circuit training in women is modified by age, baseline insulin resistance and physical capacity. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31102684 |full-text-url=https://sci-hub.do/10.1016/j.diabres.2019.05.009 }} * {{medline-title |title=The effects of vitamin-rich carbohydrate pretreatment on the surgical stress response and S-100β after splenectomy in elderly rats. |date=15.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092210 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521353 }} * {{medline-title |title=Stem Cell-Derived Exosomes Prevent Aging-Induced Cardiac Dysfunction through a Novel Exosome/lncRNA MALAT1/NF-[i]κ[/i]B/[[TNF]]-[i]α[/i] Signaling Pathway. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31089420 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476062 }} * {{medline-title |title=Endothelial PPARγ Is Crucial for Averting Age-Related Vascular Dysfunction by Stalling Oxidative Stress and ROCK. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31055770 |full-text-url=https://sci-hub.do/10.1007/s12640-019-00047-5 }} * {{medline-title |title=Melatonin alleviates cognition impairment by antagonizing brain insulin resistance in aged rats fed a high-fat diet. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31050371 |full-text-url=https://sci-hub.do/10.1111/jpi.12584 }} * {{medline-title |title=Age-related cytokine effects on cancer-related fatigue and quality of life in acute myeloid leukemia. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31080166 |full-text-url=https://sci-hub.do/10.1016/j.jgo.2019.04.009 }} * {{medline-title |title=Protective effect of vildagliptin on [[TNF]]-α-induced chondrocyte senescence. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026379 |full-text-url=https://sci-hub.do/10.1002/iub.2049 }} * {{medline-title |title=Platelet-Rich Plasma (PRP) From Older Males With Knee Osteoarthritis Depresses Chondrocyte Metabolism and Upregulates Inflammation. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31042308 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824920 }} * {{medline-title |title=Effects of sulforaphane on D-galactose-induced liver aging in rats: Role of keap-1/nrf-2 pathway. |date=15.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31039346 |full-text-url=https://sci-hub.do/10.1016/j.ejphar.2019.04.043 }} * {{medline-title |title=Protective effects of pyrroloquinoline quinine against oxidative stress-induced cellular senescence and inflammation in human renal tubular epithelial cells via Keap1/Nrf2 signaling pathway. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31035086 |full-text-url=https://sci-hub.do/10.1016/j.intimp.2019.04.040 }} * {{medline-title |title=Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice. |date=02.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31048563 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535057 }} * {{medline-title |title=Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31004310 |full-text-url=https://sci-hub.do/10.1007/s11010-019-03540-9 }} * {{medline-title |title=Resveratrol attenuates inflammation environment-induced nucleus pulposus cell senescence [i]in vitro[/i]. |date=31.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30962260 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509054 }} * {{medline-title |title=Photobiomodulation and Coenzyme Q Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30983970 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434313 }} * {{medline-title |title=Circulating factors associated with sarcopenia during ageing and after intensive lifestyle intervention. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30969486 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596393 }} * {{medline-title |title=2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms. |date=01.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30939745 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479705 }} * {{medline-title |title=N-acetylcysteine and alpha-lipoic acid improve antioxidant defenses and decrease oxidative stress, inflammation and serum lipid levels in ovariectomized rats via estrogen-independent mechanisms. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30951973 |full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2019.02.012 }} * {{medline-title |title=Neuroprotective Effect of Dioscin on the Aging Brain. |date=30.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30935017 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479446 }} * {{medline-title |title=CSF Cytokines in Aging, Multiple Sclerosis, and Dementia. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30930904 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428695 }} * {{medline-title |title=Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872008 |full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.03.004 }} * {{medline-title |title=A double-blind, randomized trial on the effect of a broad-spectrum dietary supplement on key biomarkers of cellular aging including inflammation, oxidative stress, and DNA damage in healthy adults. |date=04.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30873472 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410633 }} * {{medline-title |title=A New Understanding of the Role of IL-1 in Age-Related Intervertebral Disc Degeneration in a Murine Model. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30875127 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697204 }} * {{medline-title |title=Methane ameliorates post-operative cognitive dysfunction by inhibiting microglia NF-κB/MAPKs pathway and promoting IL-10 expression in aged mice. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30877874 |full-text-url=https://sci-hub.do/10.1016/j.intimp.2019.03.003 }} * {{medline-title |title=Age-dependent hepatic alterations induced by a high-fat high-fructose diet. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30874869 |full-text-url=https://sci-hub.do/10.1007/s00011-019-01223-1 }} * {{medline-title |title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014 }} * {{medline-title |title=Reduced CXCL1/GRO chemokine plasma levels are a possible biomarker of elderly depression. |date=15.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30826620 |full-text-url=https://sci-hub.do/10.1016/j.jad.2019.02.042 }} * {{medline-title |title=Nontuberculous mycobacterium M. avium infection predisposes aged mice to cardiac abnormalities and inflammation. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30834643 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516181 }} * {{medline-title |title=Epigenetic Age Acceleration in Adolescence Associates With BMI, Inflammation, and Risk Score for Middle Age Cardiovascular Disease. |date=01.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30785999 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555851 }} * {{medline-title |title=Converging Paths of Pulmonary Arterial Hypertension and Cellular Senescence. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30758225 |full-text-url=https://sci-hub.do/10.1165/rcmb.2018-0329TR }} * {{medline-title |title=Gender-specific association of body composition with inflammatory and adipose-related markers in healthy elderly Europeans from the NU-AGE study. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30715588 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682581 }} * {{medline-title |title=Lifelong aerobic exercise protects against inflammaging and cancer. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30682077 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347267 }} * {{medline-title |title=Individual and combined effects of salinity and lipopolysaccharides on the immune response of juvenile Takifugu fasciatus. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30656452 |full-text-url=https://sci-hub.do/10.1007/s10695-018-0607-9 }} * {{medline-title |title=The Role of Genetic Profile in Functional Performance Adaptations to Exercise Training or Physical Activity: A Systematic Review of the Literature. |date=01.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30676214 |full-text-url=https://sci-hub.do/10.1123/japa.2018-0155 }} * {{medline-title |title=Impact of simulated biological aging on physicochemical and biocompatibility properties of cyclic olefin copolymers. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30678923 |full-text-url=https://sci-hub.do/10.1016/j.msec.2018.12.032 }} * {{medline-title |title=Protective Role of Endogenous Kallistatin in Vascular Injury and Senescence by Inhibiting Oxidative Stress and Inflammation. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30622668 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304815 }} * {{medline-title |title=Lifelong exercise practice and immunosenescence: Master athletes cytokine response to acute exercise. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30616033 |full-text-url=https://sci-hub.do/10.1016/j.cyto.2018.12.006 }} * {{medline-title |title=Human T2R38 Bitter Taste Receptor Expression in Resting and Activated Lymphocytes. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30619309 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297872 }} * {{medline-title |title=Ameliorative effect of supercritical fluid extract of Chrysanthemum indicum Linnén against D-galactose induced brain and liver injury in senescent mice via suppression of oxidative stress, inflammation and apoptosis. |date=24.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30610932 |full-text-url=https://sci-hub.do/10.1016/j.jep.2018.12.050 }} * {{medline-title |title=[Effect of saponins extracted from Panax japonicas on inhibiting myocardial fibrosis by TGF-β1/Smad3 signaling pathway in aging rats]. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30593247 |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180724.006 }} * {{medline-title |title=Aging and Hyperglycemia Intensify Dyslipidemia-Induced Oxidative Stress and Inflammation in Rats: Assessment of Restorative Potentials of ALA and EPA DHA. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30535619 |full-text-url=https://sci-hub.do/10.1007/s10753-018-0949-6 }} * {{medline-title |title=CD56bright cells respond to stimulation until very advanced age revealing increased expression of cellular protective proteins [[SIRT1]], HSP70 and [[SOD2]]. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30534181 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262966 }} * {{medline-title |title=Role of Exercise in Vascular Function and Inflammatory Profile in Age-Related Obesity. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30510967 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230399 }} * {{medline-title |title=Establishment of a lethal aged mouse model of human respiratory syncytial virus infection. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30503888 |full-text-url=https://sci-hub.do/10.1016/j.antiviral.2018.11.015 }} * {{medline-title |title=Elevated truncated oxidized phospholipids as a factor exacerbating ALI in the aging lungs. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30521374 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404557 }} * {{medline-title |title=Effect of Myricetin on Primary Open-angle Glaucoma. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30473883 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234474 }} * {{medline-title |title=Chronic rhinosinusitis in elderly patients is associated with an exaggerated neutrophilic proinflammatory response to pathogenic bacteria. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30468775 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408962 }} * {{medline-title |title=Nuclear Translocation of Argonaute 2 in Cytokine-Induced Senescence. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30476917 |full-text-url=https://sci-hub.do/10.1159/000495490 }} * {{medline-title |title=Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence. |date=11.12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30478051 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294934 }} * {{medline-title |title=Association of pro-inflammatory cytokines and monocyte subtypes in older and younger patients on clinical outcomes after mechanical circulatory support device implantation. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30445099 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115755 }} * {{medline-title |title=Adipose [[TSHB]] in Humans and Serum TSH in Hypothyroid Rats Inform About Cellular Senescence. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30448824 |full-text-url=https://sci-hub.do/10.1159/000495170 }} * {{medline-title |title=Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30426301 |full-text-url=https://sci-hub.do/10.1007/s11010-018-3466-x }} * {{medline-title |title=Higher levels of tumor necrosis factor β are associated with frailty in socially vulnerable community-dwelling older adults. |date=06.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400833 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219095 }} * {{medline-title |title=Epigenetics of Delirium and Aging: Potential Role of DNA Methylation Change on Cytokine Genes in Glia and Blood Along With Aging. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30405391 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206747 }} * {{medline-title |title=Polydatin suppresses nucleus pulposus cell senescence, promotes matrix homeostasis and attenuates intervertebral disc degeneration in rats. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30358118 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201341 }} * {{medline-title |title=Ellagic acid reveals promising anti-aging effects against d-galactose-induced aging on human neuroblastoma cell line, SH-SY5Y: A mechanistic study. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30372874 |full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.10.024 }} * {{medline-title |title=The Neuro-Immuno-Senescence Integrative Model (NISIM) on the Negative Association Between Parasympathetic Activity and Cellular Senescence. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30369866 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194361 }} * {{medline-title |title=Human umbilical cord blood plasma alleviates age-related olfactory dysfunction by attenuating peripheral [[TNF]]-α expression. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30293545 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507851 }} * {{medline-title |title=Manipulating fenestrations in young and old liver sinusoidal endothelial cells. |date=01.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30285464 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383376 }} * {{medline-title |title=The Synergy of Aging and LPS Exposure in a Mouse Model of Parkinson's Disease. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30271656 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147589 }} * {{medline-title |title=Myeloid cell-derived tumor necrosis factor-alpha promotes sarcopenia and regulates muscle cell fusion with aging muscle fibers. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30256507 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260911 }} * {{medline-title |title=mRNA expressions of peroxisome proliferator-activated receptor gamma coactivator 1α, tumor necrosis factor-α, and interleukin-6 in paraspinal muscles of patients with lumbar kyphosis: a preliminary study. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30233161 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135076 }} * {{medline-title |title=Leptin stimulates the release of pro-inflammatory cytokines in hypothalamic astrocyte cultures from adult and aged rats. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229384 |full-text-url=https://sci-hub.do/10.1007/s11011-018-0311-6 }} * {{medline-title |title=Effects of 8-week kettlebell training on body composition, muscle strength, pulmonary function, and chronic low-grade inflammation in elderly women with sarcopenia. |date=02.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30243898 |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.09.015 }} * {{medline-title |title=Research advances in the regulation of the putative ovarian germline stem cell niche on female germline stem cells. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30204491 |full-text-url=https://sci-hub.do/10.1080/19396368.2018.1515272 }} * {{medline-title |title=Efficacy and safety of biological agents in the older rheumatoid arthritis patients compared to Young: A systematic review and meta-analysis. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30185379 |full-text-url=https://sci-hub.do/10.1016/j.semarthrit.2018.07.009 }} * {{medline-title |title=Leptin, hsCRP, [[TNF]]-α and IL-6 levels from normal aging to dementia: Relationship with cognitive and functional status. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30150062 |full-text-url=https://sci-hub.do/10.1016/j.jocn.2018.08.027 }} * {{medline-title |title=Systemic Inflammation Mediates Age-Related Cognitive Deficits. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30127734 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088306 }} * {{medline-title |title=Featured Article: Deterioration of visual function mediated by senescence-associated endoplasmic reticulum stress in inflammatory tie2-[[TNF]] mice. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30114984 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180406 }} * {{medline-title |title=Quercetin Enhances Ligand-induced Apoptosis in Senescent Idiopathic Pulmonary Fibrosis Fibroblasts and Reduces Lung Fibrosis In Vivo. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30109946 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348716 }} * {{medline-title |title=Bioactive Peptide Improves Diet-Induced Hepatic Fat Deposition and Hepatocyte Proinflammatory Response in SAMP8 Ageing Mice. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30092591 |full-text-url=https://sci-hub.do/10.1159/000492518 }} * {{medline-title |title=Senescence and odontoblastic differentiation of dental pulp cells. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30078208 |full-text-url=https://sci-hub.do/10.1002/jcp.26905 }} * {{medline-title |title=Effect of resistance training on inflammatory markers of older adults: A meta-analysis. |date=01.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071283 |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.07.021 }} * {{medline-title |title=Heat-induced extracellular HSP72 release is blunted in elderly diabetic people compared with healthy middle-aged and older adults, but it is partially restored by resistance training. |date=01.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30053413 |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.07.014 }} * {{medline-title |title=Repeated abortion in adulthood induces cognition impairment in aged mice. |date=30.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30061639 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065382 }} * {{medline-title |title=Cumulus cell-released tumor necrosis factor ([[TNF]])-α promotes post-ovulatory aging of mouse oocytes. |date=26.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048240 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075436 }} * {{medline-title |title=Comparison of neurotoxicity of dexmedetomidine as an adjuvant in brachial plexus block in rats of different age. |date=09-10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30017939 |full-text-url=https://sci-hub.do/10.1016/j.ntt.2018.07.001 }} * {{medline-title |title=Inflammatory cytokines and immune system modulation by aerobic versus resisted exercise training for elderly. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29977265 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016983 }} * {{medline-title |title=Age-Related Adverse Inflammatory and Metabolic Changes Begin Early in Adulthood. |date=15.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29985987 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376106 }} * {{medline-title |title=Inhibition of programmed necrosis limits infarct size through altered mitochondrial and immune responses in the aged female rat heart. |date=01.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29957016 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297819 }} * {{medline-title |title=Accumulation of T-helper 22 cells, interleukin-22 and myeloid-derived suppressor cells promotes gastric cancer progression in elderly patients. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29928409 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006301 }} * {{medline-title |title=Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence. |date=26.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941029 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019307 }} * {{medline-title |title=The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye. |date=13.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905533 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046230 }} * {{medline-title |title=Regulation of p38 mitogen-activated kinase-mediated fetal membrane senescence by statins. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29911323 |full-text-url=https://sci-hub.do/10.1111/aji.12999 }} * {{medline-title |title=Identification of proteins potentially associated with renal aging in rats. |date=14.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29907735 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046247 }} * {{medline-title |title=Aerobic Exercise Protects from Pseudomonas aeruginosa-Induced Pneumonia in Elderly Mice. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29843140 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757150 }} * {{medline-title |title=Serum Tumor Necrosis Factor-alpha associates with Myocardial Oxygen Demand and Exercise Tolerance in Postmenopausal Women. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29795723 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955286 }} * {{medline-title |title=Exercise related anxiety-like behaviours are mediated by [[TNF]] receptor signaling, but not depression-like behaviours. |date=15.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29800552 |full-text-url=https://sci-hub.do/10.1016/j.brainres.2018.05.032 }} * {{medline-title |title=Accelerated vascular aging and persistent cognitive impairment in older female breast cancer survivors. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29804200 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060197 }} * {{medline-title |title=Features of Cytokine Profile in Different Age Groups. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29805902 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960941 }} * {{medline-title |title=Anthocyanins Improve Hippocampus-Dependent Memory Function and Prevent Neurodegeneration via JNK/Akt/GSK3β Signaling in LPS-Treated Adult Mice. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29779175 |full-text-url=https://sci-hub.do/10.1007/s12035-018-1101-1 }} * {{medline-title |title=Supplementation with eicosapentaenoic acid and docosahexaenoic acid reduces high levels of circulating proinflammatory cytokines in aging adults: A randomized, controlled study. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29735019 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941937 }} * {{medline-title |title=Effects of nutritional state, aging and high chronic intake of sucrose on brain protein synthesis in rats: modulation of it by rutin and other micronutrients. |date=23.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29741190 |full-text-url=https://sci-hub.do/10.1039/c7fo01953j }} * {{medline-title |title=Plasma zinc in institutionalized elderly individuals: Relation with immune and cardiometabolic biomarkers. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29716762 |full-text-url=https://sci-hub.do/10.1016/j.jtemb.2018.04.026 }} * {{medline-title |title=Pentoxifylline, dexamethasone and azithromycin demonstrate distinct age-dependent and synergistic inhibition of TLR- and inflammasome-mediated cytokine production in human newborn and adult blood in vitro. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29715306 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929513 }} * {{medline-title |title=Necroptosis increases with age and is reduced by dietary restriction. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29696779 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052392 }} * {{medline-title |title=Age-Related Changes to Human Tear Composition. |date=01.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29677365 |full-text-url=https://sci-hub.do/10.1167/iovs.17-23358 }} * {{medline-title |title=Inhibition of UVB-induced pro-inflammatory cytokines and MMP expression by Zanthoxylum rhetsa bark extract and its active constituent hesperidin. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29672974 |full-text-url=https://sci-hub.do/10.1002/ptr.6092 }} * {{medline-title |title=Effects of Baicalein on Cortical Proinflammatory Cytokines and the Intestinal Microbiome in Senescence Accelerated Mouse Prone 8. |date=18.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29668250 |full-text-url=https://sci-hub.do/10.1021/acschemneuro.8b00074 }} * {{medline-title |title=Probiotic Potential of [i]Enterococcus faecium[/i] Isolated from Chicken Cecum with Immunomodulating Activity and Promoting Longevity in [i]Caenorhabditis elegans[/i]. |date=28.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29642285 |full-text-url=https://sci-hub.do/10.4014/jmb.1802.02019 }} * {{medline-title |title=Sex Differences in Adipose Tissue CD8 T Cells and Regulatory T Cells in Middle-Aged Mice. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29670627 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893719 }} * {{medline-title |title=Elderly dendritic cells respond to LPS/IFN-γ and [[CD40]]L stimulation despite incomplete maturation. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29652910 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898732 }} * {{medline-title |title=Inosine improves cognitive function and decreases aging-induced oxidative stress and neuroinflammation in aged female rats. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29619603 |full-text-url=https://sci-hub.do/10.1007/s10787-018-0476-y }} * {{medline-title |title=Cytokine Responses to Acute Exercise in Healthy Older Adults: The Effect of Cardiorespiratory Fitness. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29599722 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862854 }} * {{medline-title |title=No requirement of interlukine-1 for long-term potentiation in the anterior cingulate cortex of adult mice. |date=01-12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29592781 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882040 }} * {{medline-title |title=[Electroacupuncture Intervention Improves Physical Power of Aged Rats with Low Testosterone by Reducing Chronic Inflammatory Response of Leydig Cells]. |date=25.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29560631 |full-text-url=https://sci-hub.do/10.13702/j.1000-0607.170705 }} * {{medline-title |title=Predominant gut Lactobacillus murinus strain mediates anti-inflammaging effects in calorie-restricted mice. |date=21.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29562943 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863386 }} * {{medline-title |title=Proximity of Cytomegalovirus-Specific CD8 T Cells to Replicative Senescence in Human Immunodeficiency Virus-Infected Individuals. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29527205 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829617 }} * {{medline-title |title=Xanthohumol exerts protective effects in liver alterations associated with aging. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29536163 |full-text-url=https://sci-hub.do/10.1007/s00394-018-1657-6 }} * {{medline-title |title=Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487806 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824071 }} * {{medline-title |title=Exercise and taurine in inflammation, cognition, and peripheral markers of blood-brain barrier integrity in older women. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29474803 |full-text-url=https://sci-hub.do/10.1139/apnm-2017-0775 }} * {{medline-title |title=Normal aging induces A1-like astrocyte reactivity. |date=20.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29437957 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828643 }} * {{medline-title |title=Human blood MAIT cell subsets defined using [[MR1]] tetramers. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29437263 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446826 }} * {{medline-title |title=The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence. |date=15.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29449647 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833376 }} * {{medline-title |title=Nucleoside Reverse Transcriptase Inhibitors (NRTIs) Induce Pathological Pain through Wnt5a-Mediated Neuroinflammation in Aging Mice. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29429030 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930064 }} * {{medline-title |title=Aged Chinese-origin rhesus macaques infected with SIV develop marked viremia in absence of clinical disease, inflammation or cognitive impairment. |date=01.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29391069 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796498 }} * {{medline-title |title=Protective effect of crocin against d-galactose-induced aging in mice. |date=01-02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29387570 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787993 }} * {{medline-title |title=Osteogenic protein-1 attenuates the inflammatory cytokine-induced NP cell senescence through regulating the ROS/NF-κB pathway. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29367112 |full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.01.053 }} * {{medline-title |title=Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older adults. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29383869 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847877 }} * {{medline-title |title=Impairment of Several Immune Functions and Redox State in Blood Cells of Alzheimer's Disease Patients. Relevant Role of Neutrophils in Oxidative Stress. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29375582 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768621 }} * {{medline-title |title=[Effect of saponins extracted from Panax japonicus on inhibiting cardiomyocyte apoptosis by AMPK/Sirt1/NF-κB signaling pathway in aging rats]. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29376267 |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20170928.022 }} * {{medline-title |title=Premature aging in behavior and immune functions in tyrosine hydroxylase haploinsufficient female mice. A longitudinal study. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29341892 |full-text-url=https://sci-hub.do/10.1016/j.bbi.2018.01.003 }} * {{medline-title |title=Differential microRNA expression profiles and bioinformatics analysis between young and aging spontaneously hypertensive rats. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29328372 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819922 }} * {{medline-title |title=Antagonism of cysteinyl leukotriene receptor 1 (cysLTR1) by montelukast suppresses cell senescence of chondrocytes. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29331588 |full-text-url=https://sci-hub.do/10.1016/j.cyto.2017.12.021 }} * {{medline-title |title=Rapamycin prevents the intervertebral disc degeneration via inhibiting differentiation and senescence of annulus fibrosus cells. |date=18.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29348392 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811247 }} * {{medline-title |title=Memory enhancement and protective effects of crocin against D-galactose aging model in the hippocampus of Wistar rats. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29299203 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749360 }} * {{medline-title |title=The additive effect of aging on sepsis-induced cognitive impairment and neuroinflammation. |date=15.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29301654 |full-text-url=https://sci-hub.do/10.1016/j.jneuroim.2017.11.014 }} * {{medline-title |title=Cytomegalovirus-Specific T Cells Restricted by [[HLA-C]]w*0702 Increase Markedly with Age and Dominate the CD8 T-Cell Repertoire in Older People. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29312307 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732243 }} * {{medline-title |title=Polar extract of Curcuma longa protects cartilage homeostasis: possible mechanism of action. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29313174 |full-text-url=https://sci-hub.do/10.1007/s10787-017-0433-1 }} * {{medline-title |title=Immunoglobulin therapy ameliorates the phenotype and increases lifespan in the severely affected dystrophin-utrophin double knockout mice. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29255177 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865115 }} * {{medline-title |title=The Association between Modulating Inflammatory Cytokines and Constipation of Geriatrics in Iran. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29255581 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726336 }} * {{medline-title |title=Immune senescence and biomarkers profile of Bambuí aged population-based cohort. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29247791 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.12.006 }} * {{medline-title |title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 }} * {{medline-title |title=[[TNF]]-α antagonism with etanercept enhances penile NOS expression, cavernosal reactivity, and testosterone levels in aged rats. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29260891 |full-text-url=https://sci-hub.do/10.1139/cjpp-2017-0113 }} * {{medline-title |title=Dietary Animal Plasma Proteins Improve the Intestinal Immune Response in Senescent Mice. |date=11.12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29232896 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748796 }} * {{medline-title |title=Effects of the Consumption of Milk Biofortified with Selenium, Vitamin E, and Different Fatty Acid Profile on Immune Response in the Elderly. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29193757 |full-text-url=https://sci-hub.do/10.1002/mnfr.201700307 }} * {{medline-title |title=Phase angle is related with inflammatory and oxidative stress biomarkers in older women. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29197561 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.019 }} * {{medline-title |title=Practice Patterns in Hepatitis B Virus Screening Before Cancer Chemotherapy in a Major US Hospital Network. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177849 |full-text-url=https://sci-hub.do/10.1007/s10620-017-4850-1 }} * {{medline-title |title=Insulin-Like Growth Factor-1 and Neuroinflammation. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163145 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675852 }} * {{medline-title |title=Enhancement of cutaneous immunity during aging by blocking p38 mitogen-activated protein (MAP) kinase-induced inflammation. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29155150 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127037 }} * {{medline-title |title=Fisetin as a caloric restriction mimetic protects rat brain against aging induced oxidative stress, apoptosis and neurodegeneration. |date=15.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29122553 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2017.11.004 }} * {{medline-title |title=Tucum-do-Cerrado (Bactris setosa Mart.) May Promote Anti-Aging Effect by Upregulating [[SIRT1]]-Nrf2 Pathway and Attenuating Oxidative Stress and Inflammation. |date=14.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135935 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707715 }} * {{medline-title |title=Time-response characteristic and potential biomarker identification of heavy metal induced toxicity in zebrafish. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29111395 |full-text-url=https://sci-hub.do/10.1016/j.fsi.2017.10.047 }} * {{medline-title |title=Targeting of AUF1 to vascular endothelial cells as a novel anti-aging therapy. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29089968 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653898 }} * {{medline-title |title=Age-related decline of the acute local inflammation response: a mitigating role for the adenosine A receptor. |date=18.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29064819 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680557 }} * {{medline-title |title=Anthocyanins Delay Ageing-Related Degenerative Changes in the Liver. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29075987 |full-text-url=https://sci-hub.do/10.1007/s11130-017-0644-z }} * {{medline-title |title=Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of [[BDNF]]/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats. |date=06.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29065194 |full-text-url=https://sci-hub.do/10.1093/ntr/ntx157 }} * {{medline-title |title=Study of insulin vascular sensitivity in aortic rings and endothelial cells from aged rats subjected to caloric restriction: Role of perivascular adipose tissue. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055722 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.10.017 }} * {{medline-title |title=Tumor necrosis factor-alpha and soluble [[TNF]]-alpha receptor responses in young vs. middle-aged males following eccentric exercise. |date=15.12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29038027 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.10.012 }} * {{medline-title |title=Chronic inflammation - inflammaging - in the ageing cochlea: A novel target for future presbycusis therapy. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29017893 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675822 }} * {{medline-title |title=Allogeneic Mesenchymal Stem Cells Ameliorate Aging Frailty: A Phase II Randomized, Double-Blind, Placebo-Controlled Clinical Trial. |date=12.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28977399 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861900 }} * {{medline-title |title=Protective effect of xanthohumol against age-related brain damage. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28950154 |full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2017.07.011 }} * {{medline-title |title=7,8-Dihydroxyflavone attenuates [[TNF]]-α-induced skin aging in Hs68 human dermal fibroblast cells via down-regulation of the MAPKs/Akt signaling pathways. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28950658 |full-text-url=https://sci-hub.do/10.1016/j.biopha.2017.09.098 }} * {{medline-title |title=Influenza vaccine-mediated protection in older adults: Impact of influenza infection, cytomegalovirus serostatus and vaccine dosage. |date=01.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28958701 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871551 }} * {{medline-title |title=Aged blood factors decrease cellular responses associated with delayed gingival wound repair. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28898261 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595322 }} * {{medline-title |title=Age-associated alterations in the levels of cytotoxic lipid molecular species and oxidative stress in the murine thymus are reduced by growth hormone treatment. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28865931 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819751 }} * {{medline-title |title=Force-time characteristics during sustained maximal handgrip effort according to age and clinical condition. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28864229 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.033 }} * {{medline-title |title=[Age-related aspects of the involvement of heat shock proteins in the pathogenesis of osteoarthritis]. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28849876 }} * {{medline-title |title=Electroacupuncture alleviates surgery-induced cognitive dysfunction by increasing α7-nAChR expression and inhibiting inflammatory pathway in aged rats. |date=17.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28842280 |full-text-url=https://sci-hub.do/10.1016/j.neulet.2017.08.043 }} * {{medline-title |title=Association between local inflammation and breast tissue age-related lobular involution among premenopausal and postmenopausal breast cancer patients. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28846716 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573208 }} * {{medline-title |title=Cytochrome P450-2E1 is involved in aging-related kidney damage in mice through increased nitroxidative stress. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28843596 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656532 }} * {{medline-title |title=Tumor necrosis factor alpha polymorphisms are associated with Parkinson's disease age at onset. |date=29.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28844731 |full-text-url=https://sci-hub.do/10.1016/j.neulet.2017.08.049 }} * {{medline-title |title=Involvement of insulin resistance in D-galactose-induced age-related dementia in rats: Protective role of metformin and saxagliptin. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28832656 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568415 }} * {{medline-title |title=Lower levels of interleukin-1β gene expression are associated with impaired Langerhans' cell migration in aged human skin. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28777886 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721243 }} * {{medline-title |title=Predictive value of multiple cytokines and chemokines for mortality in an admixed population: 15-year follow-up of the Bambui-Epigen (Brazil) cohort study of aging. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28803133 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.002 }} * {{medline-title |title=Age-dependent alterations in serum cytokines, peripheral blood mononuclear cell cytokine production, natural killer cell activity, and prostaglandin F . |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28762199 |full-text-url=https://sci-hub.do/10.1007/s12026-017-8940-0 }} * {{medline-title |title=Role of Kallistatin Treatment in Aging and Cancer by Modulating miR-34a and miR-21 Expression. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28744338 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506461 }} * {{medline-title |title=Counts of [[MSC]] in the Bone Marrow of Young and Old CBA Mice after a Single Exposure to Osteogenic Stimuli (Curettage, BMP-2 Injection) or Antigens (S. typhimurium Antigenic Complex) and in Heterotopic Bone Marrow Transplants. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28744638 |full-text-url=https://sci-hub.do/10.1007/s10517-017-3805-z }} * {{medline-title |title=Effect of Exercise on Inflammatory Profile of Older Persons: Systematic Review and Meta-Analyses. |date=01.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28771081 |full-text-url=https://sci-hub.do/10.1123/jpah.2016-0735 }} * {{medline-title |title=Emerging role of Interleukins IL-23/IL-17 axis and biochemical markers in the pathogenesis of Type 2 Diabetes: Association with age and gender in human subjects. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28757426 |full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2017.07.155 }} * {{medline-title |title=An Appropriate Modulation of Lymphoproliferative Response and Cytokine Release as Possible Contributors to Longevity. |date=24.07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28737707 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536085 }} * {{medline-title |title=Intestinal Permeability Biomarker Zonulin is Elevated in Healthy Aging. |date=01.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676292 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581307 }} * {{medline-title |title=Tumor-targeted IL-12 combined with local irradiation leads to systemic tumor control via abscopal effects [i]in vivo[/i]. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28680762 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486191 }} * {{medline-title |title=The relation between DNA methylation patterns and serum cytokine levels in community-dwelling adults: a preliminary study. |date=21.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28637423 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480116 }} * {{medline-title |title=Critical role of [[TNF]] inhibition in combination therapy for elderly mice with atherosclerosis. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28643478 |full-text-url=https://sci-hub.do/10.1111/1755-5922.12280 }} * {{medline-title |title=Structural characterization of a pectic polysaccharide from Codonopsis pilosula and its immunomodulatory activities in vivo and in vitro. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28600205 |full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2017.06.023 }} * {{medline-title |title=p21 maintains senescent cell viability under persistent DNA damage response by restraining JNK and caspase signaling. |date=01.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28607003 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538795 }} * {{medline-title |title=A dual agonist of farnesoid X receptor (FXR) and the G protein-coupled receptor TGR5, INT-767, reverses age-related kidney disease in mice. |date=21.07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28596381 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519354 }} * {{medline-title |title=Deregulation of hsa-miR-20b expression in [[TNF]]-α-induced premature senescence of human pulmonary microvascular endothelial cells. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28595801 |full-text-url=https://sci-hub.do/10.1016/j.mvr.2017.06.002 }} * {{medline-title |title=Identification of tissue-specific transcriptional markers of caloric restriction in the mouse and their use to evaluate caloric restriction mimetics. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28556428 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506434 }} * {{medline-title |title=Grip strength and inflammatory biomarker profiles in very old adults. |date=01.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28541423 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860623 }} * {{medline-title |title=Anti-aging drugs reduce hypothalamic inflammation in a sex-specific manner. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28544365 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506421 }} * {{medline-title |title=Kallistatin reduces vascular senescence and aging by regulating microRNA-34a-[[SIRT1]] pathway. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28544111 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506400 }} * {{medline-title |title=Role of Adipose Tissue Endothelial [[ADAM17]] in Age-Related Coronary Microvascular Dysfunction. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28473444 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484536 }} * {{medline-title |title=Peritoneal carcinomatosis of colorectal cancer is characterized by structural and functional reorganization of the tumor microenvironment inducing senescence and proliferation arrest in cancer cells. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28439450 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391678 }} * {{medline-title |title=Inflammatory Markers and Risk for Cognitive Decline in Chronic Kidney Disease: The CRIC Study. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28439566 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399682 }} * {{medline-title |title=Short-Term Fructose Feeding Induces Inflammation and Oxidative Stress in the Hippocampus of Young and Adult Rats. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28455700 |full-text-url=https://sci-hub.do/10.1007/s12035-017-0518-2 }} * {{medline-title |title=Allogeneic Human Mesenchymal Stem Cell Infusions for Aging Frailty. |date=12.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28444181 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861970 }} * {{medline-title |title=The isozyme selective phosphodiesterase-4 inhibitor, ABI-4, attenuates the effects of lipopolysaccharide in human cells and rodent models of peripheral and CNS inflammation. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28438557 |full-text-url=https://sci-hub.do/10.1016/j.bbi.2017.04.015 }} * {{medline-title |title=Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction. |date=12.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28407483 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392495 }} * {{medline-title |title=Effects of vitamin D and resveratrol on metabolic associated markers in liver and adipose tissue from SAMP8 mice. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28411010 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.03.017 }} * {{medline-title |title=Novel Senescent Regulatory T-Cell Subset with Impaired Suppressive Function in Rheumatoid Arthritis. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28373873 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357868 }} * {{medline-title |title=Long-term culture with lipopolysaccharide induces dose-dependent cytostatic and cytotoxic effects in THP-1 monocytes. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28341289 |full-text-url=https://sci-hub.do/10.1016/j.tiv.2017.03.009 }} * {{medline-title |title=Arginase-II Promotes Tumor Necrosis Factor-α Release From Pancreatic Acinar Cells Causing β-Cell Apoptosis in Aging. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28356309 |full-text-url=https://sci-hub.do/10.2337/db16-1190 }} * {{medline-title |title=Consumption of green tea epigallocatechin-3-gallate enhances systemic immune response, antioxidative capacity and HPA axis functions in aged male swiss albino mice. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28341876 |full-text-url=https://sci-hub.do/10.1007/s10522-017-9696-6 }} * {{medline-title |title=17beta-estradiol Attenuates [[TNF]]-α-Induced Premature Senescence of Nucleus Pulposus Cells through Regulating the ROS/NF-κB Pathway. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28255267 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332869 }} * {{medline-title |title=Frailty and Circulating Markers of Inflammation in HIV and HIV- Men in the Multicenter AIDS Cohort Study. |date=01.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28225718 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365031 }} * {{medline-title |title=Peripheral administration of the soluble [[TNF]] inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28237313 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464789 }} * {{medline-title |title=Interleukin-37 suppresses the inflammatory response to protect cardiac function in old endotoxemic mice. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28237874 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441934 }} * {{medline-title |title=From comorbidities of chronic obstructive pulmonary disease to identification of shared molecular mechanisms by data integration. |date=22.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28185567 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133493 }} * {{medline-title |title=High Volume Exercise Training in Older Athletes Influences Inflammatory and Redox Responses to Acute Exercise. |date=01.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28181836 |full-text-url=https://sci-hub.do/10.1123/japa.2016-0219 }} * {{medline-title |title=β -Microglobulin participates in development of lung emphysema by inducing lung epithelial cell senescence. |date=01.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28213472 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451601 }} * {{medline-title |title=CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of [[GRN]]/P[[GRN]]. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28189700 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389672 }} * {{medline-title |title=CMV-Specific T-cell Responses at Older Ages: Broad Responses With a Large Central Memory Component May Be Key to Long-term Survival. |date=15.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199648 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854018 }} * {{medline-title |title=Association of [[TNF]] Receptor 2 and [[CRP]] with GFR Decline in the General Nondiabetic Population. |date=03.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28153935 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383389 }} * {{medline-title |title=Age-dependent cellular reactions of the human immune system of humanized NOD scid gamma mice on LPS stimulus. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28162006 |full-text-url=https://sci-hub.do/10.1177/1753425917690814 }} * {{medline-title |title=Tumor antigen-specific CD8 T cells are negatively regulated by PD-1 and Tim-3 in human gastric cancer. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28110884 |full-text-url=https://sci-hub.do/10.1016/j.cellimm.2017.01.001 }} * {{medline-title |title=Noni (Morinda citrifolia L.) fruit juice reverses age-related decline in neural-immune interactions in the spleens of old F344 rats. |date=23.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28111215 |full-text-url=https://sci-hub.do/10.1016/j.jep.2017.01.034 }} * {{medline-title |title=Aging Affects Bone Marrow Macrophage Polarization: Relevance to Bone Healing. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28138512 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270653 }} * {{medline-title |title=Therapeutic effect of human ghrelin and growth hormone: Attenuation of immunosuppression in septic aged rats. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28115288 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519455 }} * {{medline-title |title=CD8 T cells of chronic HCV-infected patients express multiple negative immune checkpoints following stimulation with HCV peptides. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28104239 |full-text-url=https://sci-hub.do/10.1016/j.cellimm.2016.12.002 }} * {{medline-title |title=Microvasculature remodeling in the mouse lower gut during inflammaging. |date=03.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28045067 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206655 }} * {{medline-title |title=The role of macrophages in the susceptibility of Fc gamma receptor IIb deficient mice to Cryptococcus neoformans. |date=11.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28074867 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225418 }} * {{medline-title |title="Inflamm-aging" influences immune cell survival factors in human bone marrow. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27995612 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434810 }} * {{medline-title |title=Analysis of molecular networks and targets mining of Chinese herbal medicines on anti-aging. |date=28.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28031022 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198498 }} * {{medline-title |title=[Pathological state or cause of sarcopenia.] |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28017945 |full-text-url=https://sci-hub.do/CliCa17014552 }} * {{medline-title |title=Advanced atherosclerosis is associated with inflammation, vascular dysfunction and oxidative stress, but not hypertension. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28017665 |full-text-url=https://sci-hub.do/10.1016/j.phrs.2016.12.032 }} * {{medline-title |title=Effect of Low-Dose Rapamycin on Senescence Markers and Physical Functioning in Older Adults with Coronary Artery Disease: Results of a Pilot Study. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27883166 |full-text-url=https://sci-hub.do/10.14283/jfa.2016.112 }} * {{medline-title |title=Inverse relationship between Alzheimer's disease and cancer, and other factors contributing to Alzheimer's disease: a systematic review. |date=22.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27875990 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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27845246 |full-text-url=https://sci-hub.do/10.1016/j.bbalip.2016.11.003 }} * {{medline-title |title=Structural brain changes and all-cause mortality in the elderly population-the mediating role of inflammation. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27766478 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266221 }} * {{medline-title |title=Aging dysregulates D- and E-series resolvins to modulate cardiosplenic and cardiorenal network following myocardial infarction. |date=18.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27777380 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191859 }} * {{medline-title |title=Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization. |date=01.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27793997 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386828 }} * {{medline-title |title=Downregulation of kidney protective factors by inflammation: role of transcription factors and epigenetic mechanisms. |date=01.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27760772 |full-text-url=https://sci-hub.do/10.1152/ajprenal.00487.2016 }} * {{medline-title |title=Strain-dependent response to stimulation in middle-aged rat macrophages: A quest after a useful indicator of healthy aging. |date=01.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27756630 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.10.005 }} * {{medline-title |title=A reverse genetics cell-based evaluation of genes linked to healthy human tissue age. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27698205 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161526 }} * {{medline-title |title=Longevity-Associated [[FOXO3]] Genotype and its Impact on Coronary Artery Disease Mortality in Japanese, Whites, and Blacks: A Prospective Study of Three American Populations. 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|title=Amlodipine and atorvastatin improve ventricular hypertrophy and diastolic function via inhibiting [[TNF]]-α, IL-1β and NF-κB inflammatory cytokine networks in elderly spontaneously hypertensive rats. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27399810 |full-text-url=https://sci-hub.do/10.1016/j.biopha.2016.06.034 }} * {{medline-title |title=Long-term moderate calorie restriction inhibits inflammation without impairing cell-mediated immunity: a randomized controlled trial in non-obese humans. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27410480 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993339 }} * {{medline-title |title=Vδ2 and α/ß T cells show divergent trajectories during human aging. |date=19.07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27384987 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216693 }} * {{medline-title |title=Inflammatory Markers and the Risk of Hip and Vertebral Fractures in Men: the 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impairment of antitumor immunity in carcinoma-bearing mice and restoration by oral administration of Lentinula edodes mycelia extract. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27312060 |full-text-url=https://sci-hub.do/10.1007/s00262-016-1857-y }} * {{medline-title |title=Age-related accumulation of advanced glycation end-products-albumin, S100β, and the expressions of advanced glycation end product receptor differ in visceral and subcutaneous fat. |date=19.08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27301641 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2016.06.056 }} * {{medline-title |title=Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27294501 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983298 }} * {{medline-title |title=Role of androgens in dhea-induced rack1 expression and cytokine modulation in monocytes. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27239218 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884617 }} * {{medline-title |title=Transcriptome analysis of human ageing in male skin shows mid-life period of variability and central role of NF-κB. |date=27.05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27229172 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882522 }} * {{medline-title |title=PMK-S005 Alleviates Age-Related Gastric Acid Secretion, Inflammation, and Oxidative Status in the Rat Stomach. |date=15.09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27172930 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003198 }} * {{medline-title |title=Physical activity and inflammation: effects on gray-matter volume and cognitive decline in aging. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27159568 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867433 }} * {{medline-title |title=Intramembrane proteolysis within lysosomes. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27143694 |full-text-url=https://sci-hub.do/10.1016/j.arr.2016.04.012 }} * {{medline-title |title=Characterization of the anti-inflammatory Lactobacillus reuteri BM36301 and its probiotic benefits on aged mice. |date=19.04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27095067 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837529 }} * {{medline-title |title=The anti-aging effects of LW-AFC via correcting immune dysfunctions in senescence accelerated mouse resistant 1 (SAMR1) strain. |date=10.05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27105505 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053624 }} * {{medline-title |title=The impact of adjuvant chemotherapy in older breast cancer patients on clinical and biological aging parameters. |date=24.05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27102154 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058657 }} * {{medline-title |title=Role of mitochondrial function in cell death and body metabolism. |date=01.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27100503 |full-text-url=https://sci-hub.do/10.2741/4453 }} * {{medline-title |title=[Effect of flavonoids from Sophora flavescens in aging mice induced by D-galactos]. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27071264 }} * {{medline-title |title=Ex vivo foam cell formation is enhanced in monocytes from older individuals by both extrinsic and intrinsic mechanisms. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27073169 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.04.006 }} * {{medline-title |title=In vitro cytokine induction by TLR-activating vaccine adjuvants in human blood varies by age and adjuvant. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27081760 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906944 }} * {{medline-title |title=Joint effect of gene-physical activity and the interactions among [[CRP]], [[TNF]]-α, and [[LTA]] polymorphisms on serum [[CRP]], [[TNF]]-α levels, and handgrip strength in community-dwelling elders in Taiwan - TCHS-E. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27056089 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005924 }} * {{medline-title |title=Hippocampal Astrocyte Cultures from Adult and Aged Rats Reproduce Changes in Glial Functionality Observed in the Aging Brain. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27026184 |full-text-url=https://sci-hub.do/10.1007/s12035-016-9880-8 }} * {{medline-title |title=Wound healing delays in α-Klotho-deficient mice that have skin appearance similar to that in aged humans - Study of delayed wound healing mechanism. |date=13.05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27037022 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Physical Activity and Vascular Aging. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27000828 |full-text-url=https://sci-hub.do/10.2174/1381612822666160322144724 }} * {{medline-title |title=Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27013617 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925821 }} * {{medline-title |title=Air pollution and skin diseases: Adverse effects of airborne particulate matter on various skin diseases. |date=01.05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27018067 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2016.03.039 }} * {{medline-title |title=Aging Converts Innate B1a Cells into Potent CD8 T Cell Inducers. |date=15.04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26983789 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821757 }} * {{medline-title |title=Effects of Hydrogen-Rich Saline on Hepatectomy-Induced Postoperative Cognitive Dysfunction in Old Mice. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26993297 |full-text-url=https://sci-hub.do/10.1007/s12035-016-9825-2 }} * {{medline-title |title=Age-Associated Resident Memory CD8 T Cells in the Central Nervous System Are Primed To Potentiate Inflammation after Ischemic Brain Injury. |date=15.04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26962232 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868658 }} * {{medline-title |title=Ageing/Menopausal Status in Healthy Women and Ageing in Healthy Men Differently Affect Cardiometabolic Parameters. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26941571 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764779 }} * {{medline-title |title=Anti-[[TNF]]-α treatment modulates SASP and SASP-related microRNAs in endothelial cells and in circulating angiogenic cells. |date=15.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26943583 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914260 }} * {{medline-title |title=Agmatine Ameliorates High Glucose-Induced Neuronal Cell Senescence by Regulating the p21 and p53 Signaling. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26924930 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766111 }} * {{medline-title |title=[IMMUNE PARAMETERS OF SALIVA IN PERSONS OF DIFFERENT AGE RESIDING IN ST. PETERSBURG AND LENINGRAD REGION]. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26856091 }} * {{medline-title |title=Effects of Ageing on the Immune System: Infants to Elderly. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26808160 |full-text-url=https://sci-hub.do/10.1111/sji.12413 }} * {{medline-title |title=Targeting local vascular and systemic consequences of inflammation on vascular and cardiac valve calcification. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26788590 |full-text-url=https://sci-hub.do/10.1517/14728222.2015.1081685 }} * {{medline-title |title=Docosahexaenoic acid prevented tumor necrosis factor alpha-induced endothelial dysfunction and senescence. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26802937 |full-text-url=https://sci-hub.do/10.1016/j.plefa.2015.10.006 }} * {{medline-title |title=[[TNF]] Drives Monocyte Dysfunction with Age and Results in Impaired Anti-pneumococcal Immunity. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26766566 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713203 }} * {{medline-title |title=Association of longevity with [[TNF]]-α G308A and IL-6 G174C polymorphic inflammatory biomarkers in Caucasians: a meta-analysis. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26754162 |full-text-url=https://sci-hub.do/10.1007/s00391-015-0992-y }} * {{medline-title |title=Effect of Aging on Periodontal Inflammation, Microbial Colonization, and Disease Susceptibility. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26762510 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802783 }} * {{medline-title |title=Sirt6 regulates dendritic cell differentiation, maturation, and function. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26761436 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761712 }} * {{medline-title |title=Aging-dependent decline of IL-10 producing B cells coincides with production of antinuclear antibodies but not rheumatoid factors. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26721376 |full-text-url=https://sci-hub.do/10.1016/j.exger.2015.12.009 }} * {{medline-title |title=Kupffer cells-dependent inflammation in the injured liver increases recruitment of mesenchymal stem cells in aging mice. |date=12.01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26716516 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811445 }} * {{medline-title |title=Interaction of mouse splenocytes and macrophages with bacterial strains in vitro: the effect of age in the immune response. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26689225 |full-text-url=https://sci-hub.do/10.3920/BM2015.0094 }} * {{medline-title |title=Impairment of biliverdin reductase-A promotes brain insulin resistance in Alzheimer disease: A new paradigm. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26698666 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2015.12.012 }} * {{medline-title |title=Role of [[SHOX2]] in the development of intervertebral disc degeneration. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26697824 |full-text-url=https://sci-hub.do/10.1002/jor.23140 }} * {{medline-title |title=Melatonin decreases the expression of inflammation and apoptosis markers in the lung of a senescence-accelerated mice model. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26656745 |full-text-url=https://sci-hub.do/10.1016/j.exger.2015.11.021 }} * {{medline-title |title=Age-related neuroinflammation and changes in AKT-GSK-3β and WNT/ β-CATENIN signaling in rat hippocampus. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26647069 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712335 }} * {{medline-title |title=Aging has small effects on initial ischemic acute kidney injury development despite changing intrarenal immunologic micromilieu in mice. |date=15.02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26661651 |full-text-url=https://sci-hub.do/10.1152/ajprenal.00217.2015 }} * {{medline-title |title=Inflammaging and Anti-Inflammaging: The Role of Cytokines in Extreme Longevity. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26658771 |full-text-url=https://sci-hub.do/10.1007/s00005-015-0377-3 }} * {{medline-title |title=Effect of ZIP2 Gln/Arg/Leu (rs2234632) polymorphism on zinc homeostasis and inflammatory response following zinc supplementation. |date=11-12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26643924 |full-text-url=https://sci-hub.do/10.1002/biof.1247 }} * {{medline-title |title=Ageing and the telomere connection: An intimate relationship with inflammation. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26616852 |full-text-url=https://sci-hub.do/10.1016/j.arr.2015.11.006 }} * {{medline-title |title=Responses of Dendritic Cells to TLR-4 Stimulation Are Maintained in the Elderly and Resist the Effects of CMV Infection Seen in the Young. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26615178 |full-text-url=https://sci-hub.do/10.1093/gerona/glv119 }} * {{medline-title |title=Dietary supplementation with the polyphenol-rich açaí pulps (Euterpe oleracea Mart. and Euterpe precatoria Mart.) improves cognition in aged rats and attenuates inflammatory signaling in BV-2 microglial cells. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26618555 |full-text-url=https://sci-hub.do/10.1080/1028415X.2015.1115213 }} * {{medline-title |title=Age and diabetes related changes of the retinal capillaries: An ultrastructural and immunohistochemical study. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26604209 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806738 }} * {{medline-title |title=Melatonin Counteracts at a Transcriptional Level the Inflammatory and Apoptotic Response Secondary to Ischemic Brain Injury Induced by Middle Cerebral Artery Blockade in Aging Rats. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26594596 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642830 }} * {{medline-title |title=The relationship between inflammatory markers and voxel-based gray matter volumes in nondemented older adults. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26559883 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2015.10.008 }} * {{medline-title |title=Change in N-Glycosylation of Plasma Proteins in Japanese Semisupercentenarians. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26559536 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641608 }} * {{medline-title |title=Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs. |date=25.12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26518879 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692211 }} * {{medline-title |title=Prognostic impact of circulating Her-2-reactive T-cells producing pro- and/or anti-inflammatory cytokines in elderly breast cancer patients. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26500775 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617728 }} * {{medline-title |title=Age differences in cytokine expression under conditions of health using experimental pain models. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26456458 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664177 }} * {{medline-title |title=CLARITY and PACT-based imaging of adult zebrafish and mouse for whole-animal analysis of infections. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26449262 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728314 }} * {{medline-title |title=[Rich selenium-Banqiao-Codonopsis Pilosula mixture enhances immune function of aging mice]. |date=10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26429536 }} * {{medline-title |title=Estrogen 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vascular endothelial function of older adults. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26306566 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740211 }} * {{medline-title |title=Monocyte Phenotype and Polyfunctionality Are Associated With Elevated Soluble Inflammatory Markers, Cytomegalovirus Infection, and Functional and Cognitive Decline in Elderly Adults. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26286603 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007736 }} * {{medline-title |title=Age-related increased prevalence of asthma and nasal polyps in chronic rhinosinusitis and its association with altered IL-6 trans-signaling. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26266960 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742956 }} * {{medline-title |title=Inflammatory Markers Change with Age, but do not Fall Beyond Reported Normal Ranges. |date=06.2016 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SUCCESSFUL AGING. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26087730 }} * {{medline-title |title=Age-Dependent Alterations in the Interactions of NF-κB and N-myc with GLT-1/EAAT2 Promoter in the Pericontusional Cortex of Mice Subjected to Traumatic Brain Injury. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26081154 |full-text-url=https://sci-hub.do/10.1007/s12035-015-9287-y }} * {{medline-title |title=The Werner Protein Acts as a Coactivator of Nuclear Factor κB (NF-κB) on HIV-1 and Interleukin-8 (IL-8) Promoters. |date=24.07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26037922 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513100 }} * {{medline-title |title=Interleukin-6 as a first-rated serum inflammatory marker to predict mortality and hospitalization in the oldest old: A regression and CART approach in the BELFRAIL study. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26051931 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hypothalamic changes in the long-lived crowded litter female mice. |date=04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25907790 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425981 }} * {{medline-title |title=The probiotic mixture IRT5 ameliorates age-dependent colitis in rats. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25907245 |full-text-url=https://sci-hub.do/10.1016/j.intimp.2015.04.021 }} * {{medline-title |title=Essential role of [[POLDIP2]] in Tau aggregation and neurotoxicity via autophagy/proteasome inhibition. |date=26.06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25930997 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.04.084 }} * {{medline-title |title=Inflammaging decreases adaptive and innate immune responses in mice and humans. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25921609 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626429 }} * {{medline-title |title=Methyl-CpG Binding Protein 2 Regulates Microglia and Macrophage Gene Expression in Response to Inflammatory Stimuli. |date=21.04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25902482 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407145 }} * {{medline-title |title=Relationship between biomarkers of inflammation, oxidative stress and endothelial/microcirculatory function in successful aging versus healthy youth: a transversal study. |date=08.04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25888078 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393601 }} * {{medline-title |title=No strong correlations between serum cytokine levels, CMV serostatus and hand-grip strength in older subjects in the Berlin BASE-II cohort. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25906063 |full-text-url=https://sci-hub.do/10.1007/s10522-015-9577-9 }} * {{medline-title |title=Fibroblast growth factor 21 protects mouse brain against D-galactose induced aging via suppression of oxidative stress response and advanced glycation end products formation. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25871519 |full-text-url=https://sci-hub.do/10.1016/j.pbb.2015.03.020 }} * {{medline-title |title=The p53/miR-17/Smurf1 pathway mediates skeletal deformities in an age-related model via inhibiting the function of mesenchymal stem cells. |date=03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25855145 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394731 }} * {{medline-title |title=Acute exercise increases hippocampal [[TNF]]-α, Caspase-3 and Caspase-7 expression in healthy young and older mice. |date=04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25853879 }} * {{medline-title |title=Abrogation of adenosine A1 receptor signalling improves metabolic regulation in mice by modulating oxidative stress and inflammatory responses. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25835725 |full-text-url=https://sci-hub.do/10.1007/s00125-015-3570-3 }} * {{medline-title |title=Autophagy in axonal degeneration in glaucomatous optic neuropathy. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25816798 |full-text-url=https://sci-hub.do/10.1016/j.preteyeres.2015.03.002 }} * {{medline-title |title=Prophylactic lithium alleviates splenectomy-induced cognitive dysfunction possibly by inhibiting hippocampal [[TLR4]] activation in aged rats. |date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25839444 |full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2015.02.008 }} * {{medline-title |title=Influences of age and sex on leukocytes of healthy horses and their ex vivo cytokine release. |date=15.05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25782350 |full-text-url=https://sci-hub.do/10.1016/j.vetimm.2015.02.011 }} * {{medline-title |title=Altered neutrophil functions in elderly patients during a 6-month follow-up period after a hip fracture. |date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25797136 |full-text-url=https://sci-hub.do/10.1016/j.exger.2015.03.009 }} * {{medline-title |title=Blood-brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25784952 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362825 }} * {{medline-title |title=Association of systemic inflammation with epicardial fat and coronary artery calcification. |date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25763815 |full-text-url=https://sci-hub.do/10.1007/s00011-015-0809-x }} * {{medline-title |title=Age-associated changes in granulosa cell transcript abundance in equine preovulatory follicles. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25775380 |full-text-url=https://sci-hub.do/10.1071/RD14467 }} * {{medline-title |title=Effects of er-miao-san extracts on [[TNF]]-alpha-induced MMP-1 expression in human dermal fibroblasts. |date=26.01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761492 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417304 }} * {{medline-title |title=Immunostimulatory effects of [[RACK1]] pseudosubstrate in human leukocytes obtained from young and old donors. |date=30.03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25779661 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466631 }} * {{medline-title |title=Patient-relevant endpoints in inflammatory bowel diseases--have changes occurred in Germany over the past twelve years? |date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25740812 |full-text-url=https://sci-hub.do/10.1093/ecco-jcc/jjv041 }} * {{medline-title |title=Anti-inflammatory effect of resveratrol in old mice liver. |date=04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25687021 |full-text-url=https://sci-hub.do/10.1016/j.exger.2015.02.004 }} * {{medline-title |title=Blockade of PD-1 or p38 MAP kinase signaling enhances senescent human CD8( ) T-cell proliferation by distinct pathways. |date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25707450 |full-text-url=https://sci-hub.do/10.1002/eji.201445312 }} * {{medline-title |title=Circulating [[TNF]] and mitochondrial DNA are major determinants of neutrophil phenotype in the advanced-age, frail elderly. |date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25660689 |full-text-url=https://sci-hub.do/10.1016/j.molimm.2015.01.015 }} * {{medline-title |title=Salidroside protects against premature senescence induced by ultraviolet B irradiation in human dermal fibroblasts. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25639473 |full-text-url=https://sci-hub.do/10.1111/ics.12202 }} * {{medline-title |title=Selected pro- and anti-inflammatory cytokines in cerebrospinal fluid in normal pressure hydrocephalus. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25617881 }} * {{medline-title |title=Vaginal cytokines do not correlate with postmenopausal vulvovaginal symptoms. |date=04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25559048 |full-text-url=https://sci-hub.do/10.3109/09513590.2014.995080 }} * {{medline-title |title=Age-related differences in polyfunctional T cell responses. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25512758 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265991 }} * {{medline-title |title=Anti-apoptotic and anti-glycative effects of asiatic acid in the brain of D-galactose treated mice. |date=02.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25504333 |full-text-url=https://sci-hub.do/10.1039/c4fo00862f }} * {{medline-title |title=Dexmedetomidine improves early postoperative cognitive dysfunction in aged mice. |date=05.01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25460022 |full-text-url=https://sci-hub.do/10.1016/j.ejphar.2014.11.017 }} * {{medline-title |title=Tumor necrosis factor-α-accelerated degradation of type I collagen in human skin is associated with elevated matrix metalloproteinase (MMP)-1 and MMP-3 ex vivo. |date=01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25457675 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300401 }} * {{medline-title |title=Sodium nitrite supplementation improves motor function and skeletal muscle inflammatory profile in old male mice. |date=15.01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25377884 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297777 }} * {{medline-title |title=Pre-Operative, High-IL-6 Blood Level is a Risk Factor of Post-Operative Delirium Onset in Old Patients. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25368603 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201145 }} * {{medline-title |title=Low-grade systemic inflammation connects aging, metabolic syndrome and cardiovascular disease. |date=2015 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response to mycobacterial antigens in older life. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24370373 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003347 }} ==APOE== * {{medline-title |title=Polygenic risk score of longevity predicts longer survival across an age-continuum. |date=20.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33216869 |full-text-url=https://sci-hub.do/10.1093/gerona/glaa289 }} * {{medline-title |title=Association Between [[APOE]] Alleles and Change of Neuropsychological Tests in the Long Life Family Study. |date=17.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33216038 |full-text-url=https://sci-hub.do/10.3233/JAD-201113 }} * {{medline-title |title=The [[APOE]] gene cluster responds to air pollution factors in mice with coordinated expression of genes that differs by age in humans. |date=20.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33215813 |full-text-url=https://sci-hub.do/10.1002/alz.12230 }} * {{medline-title |title=Homozygosity in the [i][[APOE]][/i] 3 Polymorphism Is Associated With Less Depression and Higher Serum Low-Density Lipoprotein in Chinese Elderly Schizophrenics. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33178131 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593819 }} * {{medline-title |title=Effect of apolipoprotein E polymorphism on cognition and brain in the Cambridge Centre for Ageing and Neuroscience cohort. |date=01-12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33088920 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545750 }} * {{medline-title |title=Cardiovascular risk factors and [[APOE]]-ε4 status affect memory functioning in aging via changes to temporal stem diffusion. |date=18.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33070365 |full-text-url=https://sci-hub.do/10.1002/jnr.24734 }} * {{medline-title |title=[[APOE]] [i]ε[/i]4 and resting-state functional connectivity in racially/ethnically diverse older adults. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32999914 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508460 }} * {{medline-title |title=Predictors of Olfactory Decline in Aging: A Longitudinal Population-Based Study. |date=13.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32886741 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662159 }} * {{medline-title |title=When Culture Influences Genes: Positive Age Beliefs Amplify the Cognitive-Aging Benefit of [[APOE]] ε2. |date=14.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32835364 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489069 }} * {{medline-title |title=Age and the association between apolipoprotein E genotype and Alzheimer disease: A cerebrospinal fluid biomarker-based case-control study. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32817639 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446786 }} * {{medline-title |title=Estimating the 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|title=Relationship Between Amyloid-β Positivity and Progression to Mild Cognitive Impairment or Dementia over 8 Years in Cognitively Normal Older Adults. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30149452 |full-text-url=https://sci-hub.do/10.3233/JAD-180507 }} * {{medline-title |title=Lifetime Risk Factors for Functional and Cognitive Outcomes in Patients with Alzheimer's Disease. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30149448 |full-text-url=https://sci-hub.do/10.3233/JAD-180303 }} * {{medline-title |title=Microglial translational profiling reveals a convergent [[APOE]] pathway from aging, amyloid, and tau. |date=03.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30082275 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122978 }} * {{medline-title |title=Childhood socioeconomic status and genetic risk for poorer cognition in later life. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048844 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{{medline-title |title=Differential 5-year brain atrophy rates in cognitively declining and stable [[APOE]]-ε4 elders. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29911873 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126943 }} * {{medline-title |title=Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29890178 |full-text-url=https://sci-hub.do/10.1016/j.mad.2018.06.002 }} * {{medline-title |title=Using event-related fMRI to examine sustained attention processes and effects of [[APOE]] ε4 in young adults. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29856823 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983530 }} * {{medline-title |title=Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29865048 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{{medline-title |title=Neuritic and Diffuse Plaque Associations with Memory in Non-Cognitively Impaired Elderly. |date=14.07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27540968 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314669 }} * {{medline-title |title=White matter hyperintensities are more highly associated with preclinical Alzheimer's disease than imaging and cognitive markers of neurodegeneration. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27489875 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950175 }} * {{medline-title |title=[[APOE]] ε4 allele modifies the association of lead exposure with age-related cognitive decline in older individuals. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27474937 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071136 }} * {{medline-title |title=[[APOE]] genotype and stress response - a mini review. |date=25.07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27457486 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near CHRNA3/5 and [[APOE]] have age- and sex-related effects on human lifespan. |date=31.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27029810 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438072 }} * {{medline-title |title=Age, [[APOE]] and sex: Triad of risk of Alzheimer's disease. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26969397 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905558 }} * {{medline-title |title=Occupational cognitive requirements and late-life cognitive aging. |date=12.04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26984944 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831043 }} * {{medline-title |title=Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer's disease. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26962052 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006248 }} * {{medline-title |title=Genetic landscape of [[APOE]] in human 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brain connectivity differences in early MCI and normal aging populations: an fMRI study. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26409470 |full-text-url=https://sci-hub.do/10.1007/s11682-015-9451-z }} * {{medline-title |title=Effects of [[APOE]] rs429358, rs7412 and [[GSTM1]]/[[GSTT1]] Polymorphism on Plasma and Erythrocyte Antioxidant Parameters and Cognition in Old Chinese Adults. |date=24.09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26404360 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632411 }} * {{medline-title |title=Does apolipoprotein E genotype influence cognition in middle-aged individuals? |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26402402 |full-text-url=https://sci-hub.do/10.1097/WCO.0000000000000262 }} * {{medline-title |title=Diabetes is Associated with Worse Executive Function in Both Eastern and Western Populations: Shanghai Aging Study and Mayo Clinic Study of Aging. |date=2015 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|title=Interaction of Cigarette Smoking History With [[APOE]] Genotype and Age on Amyloid Level, Glucose Metabolism, and Neurocognition in Cognitively Normal Elders. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25847292 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967295 }} * {{medline-title |title=[[APOE]]4 enhances age-dependent decline in cognitive function by down-regulating an NMDA receptor pathway in EFAD-Tg mice. |date=05.03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25871877 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391134 }} * {{medline-title |title=[[APOE]] ε4 Genotype and the Risk for Subjective Cognitive Impairment in Elderly Persons. |date=Fall.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25803305 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581892 }} * {{medline-title |title=Predicting the risk of mild cognitive impairment in the Mayo Clinic Study of Aging. |date=07.04.2015 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|title=Obesity is associated with early hip fracture risk in postmenopausal women: a 25-year follow-up. |date=23.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33095419 |full-text-url=https://sci-hub.do/10.1007/s00198-020-05665-w }} * {{medline-title |title=ATM inhibition synergizes with fenofibrate in high grade serous ovarian cancer cells. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33024871 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527645 }} * {{medline-title |title=Effectiveness of adjuvant FOLFOX vs 5FU/LV in adults over age 65 with stage II and III colon cancer using a novel hybrid approach. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33015888 |full-text-url=https://sci-hub.do/10.1002/pds.5148 }} * {{medline-title |title=Age, Frailty, and Comorbidity as Prognostic Factors for Short-Term Outcomes in Patients With Coronavirus Disease 2019 in Geriatric Care. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32978065 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of primary human mesenchymal stem cells downregulates Brca1-related genes and impairs DNA double-strand break recognition. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32333827 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327915 }} * {{medline-title |title=Effect of artificial dawn light on cardiovascular function, alertness, and balance in middle-aged and older adults. |date=13.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32307533 |full-text-url=https://sci-hub.do/10.1093/sleep/zsaa082 }} * {{medline-title |title=Heart Rate Performance Curve Is Dependent on Age, Sex, and Performance. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32300582 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144539 }} * {{medline-title |title=Physical activity trajectories, mortality, hospitalization, and disability in the Toledo Study of Healthy Aging. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32163233 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432572 }} * {{medline-title |title=U-Shaped Association of Plasma Testosterone, and no Association of Plasma Estradiol, with Incidence of Fractures in Men. |date=01.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32155267 |full-text-url=https://sci-hub.do/10.1210/clinem/dgaa115 }} * {{medline-title |title=Pregnancy-Related Bone Mineral and Microarchitecture Changes in Women Aged 30 to 45 Years. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32119748 |full-text-url=https://sci-hub.do/10.1002/jbmr.3998 }} * {{medline-title |title=Analysis of the world record time for combined father and son marathon. |date=01.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31917623 |full-text-url=https://sci-hub.do/10.1152/japplphysiol.00819.2019 }} * {{medline-title |title=Age-related reductions in heart rate variability do not worsen during exposure to humid compared to dry heat: A secondary analysis. |date=2019 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|title=Kidney function and its association to imminent, short- and long-term fracture risk-a longitudinal study in older women. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31754754 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946753 }} * {{medline-title |title=Oxidatively Damaged DNA/RNA and 8-Isoprostane Levels Are Associated With the Development of Type 2 Diabetes at Older Age: Results From a Large Cohort Study. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31653645 |full-text-url=https://sci-hub.do/10.2337/dc19-1379 }} * {{medline-title |title=Associations of vigorous physical activity with all-cause, cardiovascular and cancer mortality among 64 913 adults. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31548909 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733336 }} * {{medline-title |title=Reduced cerebrovascular and cardioventilatory responses to intermittent hypoxia in elderly. |date=01.2020 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|title=Dietary diversity offsets the adverse mortality risk among older indigenous Taiwanese. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31464406 |full-text-url=https://sci-hub.do/10.6133/apjcn.201909_28(3).0019 }} * {{medline-title |title=Independent and joint effects of vascular and cardiometabolic risk factor pairs for risk of all-cause dementia: a prospective population-based study. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31455442 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948010 }} * {{medline-title |title=Work Ability and Job Survival: Four-Year Follow-Up. |date=28.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31466415 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747402 }} * {{medline-title |title=Predictivity of bioimpedance phase angle for incident disability in older adults. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31436391 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015240 }} * {{medline-title |title=Diet Quality Is Associated With Mortality in Adults Aged 80 Years and Older: A Prospective Study. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31386173 |full-text-url=https://sci-hub.do/10.1111/jgs.16089 }} * {{medline-title |title=Birthweight in offspring and cardiovascular mortality in their parents, aunts and uncles: a family-based cohort study of 1.35 million births. |date=01.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31325357 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124506 }} * {{medline-title |title=Younger- vs Older-Old Patients with Heart Failure with Preserved Ejection Fraction. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260098 |full-text-url=https://sci-hub.do/10.1111/jgs.16050 }} * {{medline-title |title=Comparison of Immune Checkpoint Inhibitors between Older and Younger Patients with Advanced or Metastatic Lung Cancer: A Systematic Review and Meta-Analysis. |date=2019 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impaired kidney function, and geriatric depressive symptoms among older people living in a rural area: a population-based study. |date=06.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400830 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219054 }} * {{medline-title |title=Office and Ambulatory Heart Rate as Predictors of Age-Related Kidney Function Decline. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30354758 |full-text-url=https://sci-hub.do/10.1161/HYPERTENSIONAHA.118.11594 }} * {{medline-title |title=Aging Alters the Relative Contributions of the Sympathetic and Parasympathetic Nervous System to Blood Pressure Control in Women. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30354803 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211807 }} * {{medline-title |title=Association between treatment of superficial bladder cancer and 10-year mortality in older adults with multiple chronic conditions. |date=01.12.2018 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{{medline-title |title=Enoch Senior's College for Korean Immigrant Seniors: Quality of Life Effects. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30058523 |full-text-url=https://sci-hub.do/10.1017/S0714980818000211 }} * {{medline-title |title=Non-AIDS Mortality Is Higher Among Successfully Treated People Living with HIV Compared with Matched HIV-Negative Control Persons: A 15-Year Follow-Up Cohort Study in Sweden. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30067408 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088250 }} * {{medline-title |title=Gain without pain: Glucose promotes cognitive engagement and protects positive affect in older adults. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29999390 |full-text-url=https://sci-hub.do/10.1037/pag0000270 }} * {{medline-title |title=Ten-year changes in ambulatory blood pressure: The prognostic value of ambulatory pulse pressure. |date=09.2018 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[i]Ooep[/i] may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes. |date=18.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955025 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085769 }} * {{medline-title |title=Progression of frailty and prevalence of osteoporosis in a community cohort of older women-a 10-year longitudinal study. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29947868 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154042 }} * {{medline-title |title=Higher spermidine intake is linked to lower mortality: a prospective population-based study. |date=01.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955838 |full-text-url=https://sci-hub.do/10.1093/ajcn/nqy102 }} * {{medline-title |title=Childhood IQ and mortality during 53 years' follow-up of Swedish men and women. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29925669 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{{medline-title |title=Anxiety and 10-Year Risk of Incident Dementia-An Association Shaped by Depressive Symptoms: Results of the Prospective Three-City Study. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29719498 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913372 }} * {{medline-title |title=Delirium as a predictor of mortality in US Medicare beneficiaries discharged from the emergency department: a national claims-level analysis up to 12 months. |date=05.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29730630 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942463 }} * {{medline-title |title=Prognostic value of cardiac troponin I assay in hospitalized elderly patients. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29728985 |full-text-url=https://sci-hub.do/10.1007/s40520-018-0965-2 }} * {{medline-title |title=The influence of participation on mortality in very old age among community-living people in Sweden. |date=02.2019 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An Application of Flexible Multivariable Approaches. |date=01.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29165696 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806578 }} * {{medline-title |title=Social isolation, health literacy, and mortality risk: Findings from the English Longitudinal Study of Ageing. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172607 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794512 }} * {{medline-title |title=Bone Loss at the Hip and Subsequent Mortality in Older Men: The Osteoporotic Fractures in Men (MrOS) Study. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29124252 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673261 }} * {{medline-title |title=Thyroid status and mortality in nonagenarians from long-lived families and the general population. |date=25.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29070732 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680564 }} * {{medline-title |title=Frailty index as a predictor of mortality: a systematic review and meta-analysis. |date=01.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29040347 |full-text-url=https://sci-hub.do/10.1093/ageing/afx162 }} * {{medline-title |title=Trajectories of IGF-I Predict Mortality in Older Adults: The Cardiovascular Health Study. |date=14.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28977343 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001890 }} * {{medline-title |title=Is orthostatic hypotension more common in individuals with atrial fibrillation?-Findings from The Irish Longitudinal Study on Ageing (TILDA). |date=01.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28985288 |full-text-url=https://sci-hub.do/10.1093/ageing/afx096 }} * {{medline-title |title=Subjective life expectancy is a risk factor for perceived health status and mortality. |date=02.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28969645 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625600 }} * {{medline-title |title=The effects of dexmedetomidine preconditioning on aged rat heart of ischaemia reperfusion injury. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28987955 |full-text-url=https://sci-hub.do/10.1016/j.rvsc.2017.09.028 }} * {{medline-title |title=Diabetes and Deficits in Cortical Bone Density, Microarchitecture, and Bone Size: Framingham [[HR]]-pQCT Study. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28929525 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771832 }} * {{medline-title |title=Gender differences in longevity in free-living older adults who eat-with-others: a prospective study in Taiwan. |date=18.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928182 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623554 }} * {{medline-title |title=Decline in effort capacity with age: Echocardiographic stress analysis in the elderly. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28921674 |full-text-url=https://sci-hub.do/10.1111/echo.13709 }} * {{medline-title |title=Impaired disengagement of attention and its relationship to emotional distress in infants at high-risk for autism spectrum disorder. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28914144 |full-text-url=https://sci-hub.do/10.1080/13803395.2017.1372368 }} * {{medline-title |title=Statins for Primary Prevention of Cardiovascular Events and Mortality in Older Men. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28892121 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681374 }} * {{medline-title |title=Galectin-3 and risk of ischaemic stroke: Reasons for Geographic and Racial Differences in Stroke cohort. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28872212 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008611 }} * {{medline-title |title=Sleep duration, mortality and the influence of age. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28856478 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680380 }} * {{medline-title |title=Comparison of yoga and walking-exercise on cardiac time intervals as a measure of cardiac function in elderly with increased pulse pressure. |date=07-08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28822516 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560911 }} * {{medline-title |title=Dietary acid load and renal function have varying effects on blood acid-base status and exercise performance across age and sex. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825967 |full-text-url=https://sci-hub.do/10.1139/apnm-2017-0279 }} * {{medline-title |title=Elite Distance Runners: A 45-Year Follow-up. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28817510 |full-text-url=https://sci-hub.do/10.1249/MSS.0000000000001407 }} * {{medline-title |title=Short-term water-based aerobic training promotes improvements in aerobic conditioning parameters of mature women. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28779920 |full-text-url=https://sci-hub.do/10.1016/j.ctcp.2017.06.001 }} * {{medline-title |title=Uric acid and incident dementia over 12 years of follow-up: a population-based cohort study. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28754803 |full-text-url=https://sci-hub.do/10.1136/annrheumdis-2016-210767 }} * {{medline-title |title=Impact of persistence and non-persistence in leisure time physical activity on coronary heart disease and all-cause mortality: The Copenhagen City Heart Study. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28728482 |full-text-url=https://sci-hub.do/10.1177/2047487317721021 }} * {{medline-title |title=The Frequency-Dependent Aerobic Exercise Effects of Hypothalamic GABAergic Expression and Cardiovascular Functions in Aged Rats. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28713263 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491914 }} * {{medline-title |title=Frequency of frailty and its association with cognitive status and survival in older Chileans. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28721027 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498773 }} * {{medline-title |title=End-stage renal disease versus death in a Portuguese cohort of elderly patients: an approach using competing event analysis. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28729248 |full-text-url=https://sci-hub.do/10.1136/jim-2017-000480 }} * {{medline-title |title=Reproducibility of 24-h heart rate variability in children. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28667574 |full-text-url=https://sci-hub.do/10.1007/s10286-017-0445-3 }} * {{medline-title |title=Heritability of resting heart rate and association with mortality in middle-aged and elderly twins. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28637897 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831408 }} * {{medline-title |title=Diabetes mellitus: a risk factor for seizures in the elderly-a population-based study. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28631057 |full-text-url=https://sci-hub.do/10.1007/s00592-017-1011-0 }} * {{medline-title |title=Age Modulates Physiological Responses during Fan Use under Extreme Heat and Humidity. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28609330 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645224 }} * {{medline-title |title=Dental Status and Compression of Life Expectancy with Disability. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28605598 |full-text-url=https://sci-hub.do/10.1177/0022034517713166 }} * {{medline-title |title=Bone microstructure in men assessed by [[HR]]-pQCT: Associations with risk factors and differences between men with normal, low, and osteoporosis-range areal BMD. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28580402 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440848 }} * {{medline-title |title=Motor function and incident dementia: a systematic review and meta-analysis. |date=01.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28541374 |full-text-url=https://sci-hub.do/10.1093/ageing/afx084 }} * {{medline-title |title=Effects of resistance training frequency on cardiorespiratory fitness in older men and women during intervention and follow-up. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28526625 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.05.012 }} * {{medline-title |title=Effect of High-Salt Diet on Age-Related High Blood Pressure and Hypothalamic Redox Signaling. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28521325 |full-text-url=https://sci-hub.do/10.1159/000472259 }} * {{medline-title |title=Cardiorespiratory responses and myocardial function within incremental exercise in healthy unmedicated older vs. young men and women. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28523609 |full-text-url=https://sci-hub.do/10.1007/s40520-017-0776-x }} * {{medline-title |title=Survival of HIV-positive patients starting antiretroviral therapy between 1996 and 2013: a collaborative analysis of cohort studies. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28501495 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555438 }} * {{medline-title |title=Changes in time spent walking and the risk of incident dementia in older Japanese people: the Ohsaki Cohort 2006 Study. |date=01.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28475691 |full-text-url=https://sci-hub.do/10.1093/ageing/afx078 }} * {{medline-title |title=Buccal telomere length and its associations with cortisol, heart rate variability, heart rate, and blood pressure responses to an acute social evaluative stressor in college students. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28482730 |full-text-url=https://sci-hub.do/10.1080/10253890.2017.1328494 }} * {{medline-title |title=Models describing metronidazole pharmacokinetics in relation to hemodynamics in turkeys. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28454000 |full-text-url=https://sci-hub.do/10.1016/j.rvsc.2017.03.014 }} * {{medline-title |title=Hearing Loss and Risk of Mild Cognitive Impairment and Dementia: Findings from the Singapore Longitudinal Ageing Study. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28420004 |full-text-url=https://sci-hub.do/10.1159/000464281 }} * {{medline-title |title=Assessment of effects of differences in trunk posture during Fowler's position on hemodynamics and cardiovascular regulation in older and younger subjects. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28408809 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384695 }} * {{medline-title |title=Age-related effects on markers of inflammation and cartilage metabolism in response to an intra-articular lipopolysaccharide challenge in horses. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28380609 |full-text-url=https://sci-hub.do/10.2527/jas.2016.1078 }} * {{medline-title |title=Association of mortality and phase angle measured by different bioelectrical impedance analysis (BIA) devices. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28381339 |full-text-url=https://sci-hub.do/10.1016/j.clnu.2017.03.023 }} * {{medline-title |title=Circulating Vitamin K Is Inversely Associated with Incident Cardiovascular Disease Risk among Those Treated for Hypertension in the Health, Aging, and Body Composition Study (Health ABC). |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28356433 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404216 }} * {{medline-title |title=Recombinant cells in the lung increase with age via de novo recombination events and clonal expansion. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28370323 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827959 }} * {{medline-title |title=Caregiving, volunteering or both? Comparing effects on health and mortality using census-based records from almost 250,000 people aged 65 and over. |date=01.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28338778 |full-text-url=https://sci-hub.do/10.1093/ageing/afx017 }} * {{medline-title |title=Sense of life worth living (ikigai) and incident functional disability in elderly Japanese: The Tsurugaya Project. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28314550 |full-text-url=https://sci-hub.do/10.1016/j.jpsychores.2017.02.013 }} * {{medline-title |title=Effect of age and gender on serum periostin: Relationship to cortical measures, bone turnover and hormones. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28323143 |full-text-url=https://sci-hub.do/10.1016/j.bone.2017.03.041 }} * {{medline-title |title=Cross-sectional Versus Longitudinal Change in a Prospective [[HR]]-pQCT Study. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28294405 |full-text-url=https://sci-hub.do/10.1002/jbmr.3129 }} * {{medline-title |title=The association between frailty, the metabolic syndrome, and mortality over the lifespan. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28281219 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411368 }} * {{medline-title |title=Impacts of Dietary Phytochemicals in the Presence and Absence of Pesticides on Longevity of Honey Bees (Apis mellifera). |date=14.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28216580 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371950 }} * {{medline-title |title=Complications during hospitalization and risk factors in elderly patients with hip fracture following integrated orthogeriatric treatment. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28233062 |full-text-url=https://sci-hub.do/10.1007/s00402-017-2646-6 }} * {{medline-title |title=Alcoholic beverage preference and diabetes incidence across Europe: the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES) project. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28225055 |full-text-url=https://sci-hub.do/10.1038/ejcn.2017.4 }} * {{medline-title |title=Social relations, depressive symptoms, and incident type 2 diabetes mellitus: The English Longitudinal Study of Ageing. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28236722 |full-text-url=https://sci-hub.do/10.1016/j.diabres.2017.01.006 }} * {{medline-title |title=No increased risk of cardiovascular events in older adults initiating dipeptidyl peptidase-4 inhibitors vs therapeutic alternatives. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28195389 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471114 }} * {{medline-title |title=Arterial Pressure, Heart Rate, and Cerebral Hemodynamics Across the Adult Life Span. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28193707 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344744 }} * {{medline-title |title=Physical inactivity is a strong risk factor for stroke in the oldest old: Findings from a multi-ethnic population (the Northern Manhattan Study). |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28093966 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490071 }} * {{medline-title |title=Cognitive Decline, Body Mass Index, and Waist Circumference in Community-Dwelling Elderly Participants. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28077009 |full-text-url=https://sci-hub.do/10.1177/0891988716686832 }} * {{medline-title |title=Maximal heart rate declines linearly with age independent of cardiorespiratory fitness levels. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28099086 |full-text-url=https://sci-hub.do/10.1080/17461391.2016.1275042 }} * {{medline-title |title=Age-Associated ALU Element Instability in White Blood Cells Is Linked to Lower Survival in Elderly Adults: A Preliminary Cohort Study. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28060910 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218400 }} * {{medline-title |title=Cortical porosity exhibits accelerated rate of change in peri- compared with post-menopausal women. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28074250 |full-text-url=https://sci-hub.do/10.1007/s00198-016-3900-4 }} * {{medline-title |title=Aging impairs double-strand break repair by homologous recombination in Drosophila germ cells. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28000382 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334535 }} * {{medline-title |title=Age-related reference curves of volumetric bone density, structure, and biomechanical parameters adjusted for weight and height in a population of healthy women: an [[HR]]-pQCT study. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27981337 |full-text-url=https://sci-hub.do/10.1007/s00198-016-3876-0 }} * {{medline-title |title=Cortical Bone Area Predicts Incident Fractures Independently of Areal Bone Mineral Density in Older Men. |date=01.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27875059 |full-text-url=https://sci-hub.do/10.1210/jc.2016-3177 }} * {{medline-title |title=The Power of Serum Uric Acid in Predicting Metabolic Syndrome Diminishes With Age in an Elderly Chinese Population. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27791221 |full-text-url=https://sci-hub.do/10.1007/s12603-015-0633-6 }} * {{medline-title |title=Age- and Sex-Dependent Changes of Intra-articular Cortical and Trabecular Bone Structure and the Effects of Rheumatoid Arthritis. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27787923 |full-text-url=https://sci-hub.do/10.1002/jbmr.3025 }} * {{medline-title |title=Paradoxical delay of senescence upon depletion of [[BRCA2]] in telomerase-deficient worms. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27761361 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055038 }} * {{medline-title |title=Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence. |date=11.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27626497 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341871 }} * {{medline-title |title=Association of Age, Systolic Blood Pressure, and Heart Rate with Adult Morbidity and Mortality after Urgent Care Visits. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27625724 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017844 }} * {{medline-title |title=Characterization of Activity and Cardiovascular Responses During Surfing in Recreational Male Surfers Between the Ages of 18 and 75 Years Old. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27623020 |full-text-url=https://sci-hub.do/10.1123/japa.2016-0041 }} * {{medline-title |title=Socioeconomic correlates of quality of life for non-Māori in advanced age: Te Puāwaitanga o Nga Tapuwae Kia ora Tonu. Life and Living in Advanced Age: a Cohort Study in New Zealand (LiLACS NZ). |date=09.09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27607082 }} * {{medline-title |title=The impacts of age and frailty on heart rate and sinoatrial node function. |date=01.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27598221 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134407 }} * {{medline-title |title=Consequences of mating and predation risk for longevity in a freshwater snail: abstinence makes the heart beat longer. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27591368 |full-text-url=https://sci-hub.do/10.1111/jeb.12976 }} * {{medline-title |title=Investigation of risk factors for mortality in aged guide dogs: A retrospective cohort study. |date=15.09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27616361 |full-text-url=https://sci-hub.do/10.1016/j.prevetmed.2016.09.002 }} * {{medline-title |title=Age-Related Sensory Impairments and Risk of Cognitive Impairment. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27611845 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073029 }} * {{medline-title |title=Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27584680 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008632 }} * {{medline-title |title=Baseline, Time-Updated, and Cumulative HIV Care Metrics for Predicting Acute Myocardial Infarction and All-Cause Mortality. |date=01.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27539575 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106607 }} * {{medline-title |title=Heart rate variability during sleep in children with autism spectrum disorder. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27491489 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106315 }} * {{medline-title |title=Aged rats show dominant modulation of lower frequency hippocampal theta rhythm during running. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27496645 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.08.001 }} * {{medline-title |title=Effect of floorball training on blood lipids, body composition, muscle strength, and functional capacity of elderly men. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27485808 |full-text-url=https://sci-hub.do/10.1111/sms.12739 }} * {{medline-title |title=The muscle quality index and mortality among males and females. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27480478 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035612 }} * {{medline-title |title=Nutrition and mortality in the elderly over 10 years of follow-up: the Three-City study. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27452277 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666086 }} * {{medline-title |title=Omega-3 polyunsaturated fatty acid supplementation attenuates blood pressure increase at onset of isometric handgrip exercise in healthy young and older humans. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27440746 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962077 }} * {{medline-title |title=Energy intake, energy required and mortality in an older population. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27406257 |full-text-url=https://sci-hub.do/10.1017/S1368980016001750 }} * {{medline-title |title=Dietary flavonoid intake and risk of incident depression in midlife and older women. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27413131 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997290 }} * {{medline-title |title=Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans. |date=01.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27391797 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induced by high glucose in human umbilical vein endothelial cells. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33149857 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585532 }} * {{medline-title |title=[[SIRT1]] Activation Using CRISPR/dCas9 Promotes Regeneration of Human Corneal Endothelial Cells through Inhibiting Senescence. |date=04.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33158256 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694272 }} * {{medline-title |title=Histone Deacetylase [[SIRT1]], Smooth Muscle Cell Function, and Vascular Diseases. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33117155 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573826 }} * {{medline-title |title=6,4'-dihydroxy-7-methoxyflavanone protects against H O -induced cellular senescence by inducing [[SIRT1]] and inhibiting phosphatidylinositol 3-kinase/Akt pathway activation. |date=27.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33111210 |full-text-url=https://sci-hub.do/10.1007/s11010-020-03951-z }} * {{medline-title |title=Isoparvifuran isolated from Dalbergia odorifera attenuates H O -induced senescence of BJ cells through [[SIRT1]] activation and AKT/mTOR pathway inhibition. |date=30.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33010892 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.09.096 }} * {{medline-title |title=[[SIRT1]] Is the Target Gene for 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside Alleviating the HUVEC Senescence. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013385 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508177 }} * {{medline-title |title=The Role of Sirtuins in Kidney Diseases. |date=12.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32932720 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555196 }} * {{medline-title |title=The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32919015 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111090 }} * {{medline-title |title=Virus-Induced Asthma Exacerbations: [[SIRT1]] Targeted Approach. |date=13.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32823491 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464235 }} * {{medline-title |title=Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32793997 |full-text-url=https://sci-hub.do/10.1007/s10522-020-09896-6 }} * {{medline-title |title=Glucose restriction delays senescence and promotes proliferation of HUVECs via the AMPK/[[SIRT1]]-FOXA3-Beclin1 pathway. |date=01.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32768436 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111053 }} * {{medline-title |title=Therapeutic Effects of SRT2104 on Lung Injury in Rats with Emphysema via Reduction of Type II Alveolar Epithelial Cell Senescence. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32722945 |full-text-url=https://sci-hub.do/10.1080/15412555.2020.1797657 }} * {{medline-title |title=Latifolin Inhibits Oxidative Stress-Induced Senescence via Upregulation of [[SIRT1]] in Human Dermal Fibroblasts. |date=01.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32404543 |full-text-url=https://sci-hub.do/10.1248/bpb.b20-00094 }} * {{medline-title |title=SRT1720-induced activation of [[SIRT1]] alleviates vascular smooth muscle cell senescence through PKA-dependent phosphorylation of AMPKα at Ser485. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32421926 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327920 }} * {{medline-title |title=miR-128 plays a critical role in murine osteoclastogenesis and estrogen deficiency-induced bone loss. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32292498 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150474 }} * {{medline-title |title=Lymphocyte senescence in COPD is associated with decreased sirtuin 1 expression in steroid resistant pro-inflammatory lymphocytes. |date=01-12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32270742 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153179 }} * {{medline-title |title=Therapeutic effects of hydro-alcoholic leaf extract of Withania somnifera on age-induced changes in daily rhythms of Sirt1, Nrf2 and Rev-erbα in the SCN of male Wistar rats. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32249404 |full-text-url=https://sci-hub.do/10.1007/s10522-020-09875-x }} * {{medline-title |title=The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32214805 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084123 }} * {{medline-title |title=Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32158519 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048230 }} * {{medline-title |title=Spatiotemporal gating of [[SIRT1]] functions by O-GlcNAcylation is essential for liver metabolic switching and prevents hyperglycemia. |date=24.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32152092 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104039 }} * {{medline-title |title=Hydrogen Sulfide Inhibits Homocysteine-Induced Neuronal Senescence by Up-Regulation of [[SIRT1]]. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32132865 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053352 }} * {{medline-title |title=[[SIRT1]] and aging related signaling pathways. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32084459 |full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111215 }} * {{medline-title |title=Tropisetron protects against brain aging via attenuating oxidative stress, apoptosis and inflammation: The role of [[SIRT1]] signaling. |date=01.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32088214 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.117452 }} * {{medline-title |title=Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of [[SIRT1]] activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32056076 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206476 }} * {{medline-title |title=Deacetylation of MRTF-A by [[SIRT1]] defies senescence induced down-regulation of collagen type I in fibroblast cells. |date=01.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32061777 |full-text-url=https://sci-hub.do/10.1016/j.bbadis.2020.165723 }} * {{medline-title |title=Chronic Polyphenon-60 or Catechin Treatments Increase Brain Monoamines Syntheses and Hippocampal [[SIRT1]] Levels Improving Cognition in Aged Rats. |date=26.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31991916 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071257 }} * {{medline-title |title=Duck Oil-loaded Nanoemulsion Inhibits Senescence of Angiotensin II-treated Vascular Smooth Muscle Cells by Upregulating [[SIRT1]]. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31970335 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957441 }} * {{medline-title |title=Two novel [[SIRT1]] activators, SCIC2 and SCIC2.1, enhance [[SIRT1]]-mediated effects in stress response and senescence. |date=06-07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31942817 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574383 }} * {{medline-title |title=Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1. |date=23.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31881011 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949053 }} * {{medline-title |title=The protective role of omentin-1 in IL-1β-induced chondrocyte senescence. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31852248 |full-text-url=https://sci-hub.do/10.1080/21691401.2019.1699803 }} * {{medline-title |title=The Lifespan Extension Ability of Nicotinic Acid Depends on Whether the Intracellular NAD Level Is Lower than the Sirtuin-Saturating Concentrations. |date=24.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31878234 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982340 }} * {{medline-title |title=Alpha-mangostin decreased cellular senescence in human umbilical vein endothelial cells. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31792920 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214571 }} * {{medline-title |title=Central nervous system [[SIRT1]] expression is required for cued and contextual fear conditioning memory responses in aging mice. |date=23.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31763496 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839599 }} * {{medline-title |title=Does education level protect us from rapid ageing? Sirtuin expression versus age and level of education. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31785216 }} * {{medline-title |title=CO ameliorates endothelial senescence induced by 5-fluorouracil through [[SIRT1]] activation. |date=30.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31704100 |full-text-url=https://sci-hub.do/10.1016/j.abb.2019.108185 }} * {{medline-title |title=Long noncoding RNA GAS5 inhibits cell proliferation and fibrosis in diabetic nephropathy by sponging miR-221 and modulating [[SIRT1]] expression. |date=20.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31631065 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834398 }} * {{medline-title |title=The Role of Sirtuin1 in Regulating Endothelial Function, Arterial Remodeling and Vascular Aging. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31572218 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751260 }} * {{medline-title |title=Deacetylation of LAMP1 drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31544977 |full-text-url=https://sci-hub.do/10.1002/jcp.29182 }} * {{medline-title |title=Plasma exosomes in OSA patients promote endothelial senescence: effect of long-term adherent continuous positive airway pressure. |date=13.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31552414 |full-text-url=https://sci-hub.do/10.1093/sleep/zsz217 }} * {{medline-title |title=Hydrogen Sulfide Inhibits High Glucose-Induced Neuronal Senescence by Improving Autophagic Flux [i]via[/i] Up-regulation of [[SIRT1]]. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31481873 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710442 }} * {{medline-title |title=Activation of the miR-34a-Mediated [[SIRT1]]/mTOR Signaling Pathway by Urolithin A Attenuates D-Galactose-Induced Brain Aging in Mice. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31420820 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985387 }} * {{medline-title |title=[Ginsenoside Rg_1 induces leukemia stem cell senescence via [[SIRT1]]/TSC_2 signal axis]. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31359662 |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20190218.002 }} * {{medline-title |title=miR-23b-3p regulates apoptosis and autophagy via suppressing [[SIRT1]] in lens epithelial cells. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31338869 |full-text-url=https://sci-hub.do/10.1002/jcb.29270 }} * {{medline-title |title=Genetic background, epigenetic factors and dietary interventions which influence human longevity. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31309340 |full-text-url=https://sci-hub.do/10.1007/s10522-019-09824-3 }} * {{medline-title |title=Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298565 |full-text-url=https://sci-hub.do/10.1089/cell.2019.0010 }} * {{medline-title |title=Interference with the bromodomain epigenome readers drives p21 expression and tumor senescence. |date=01.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31265875 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159039 }} * {{medline-title |title=Involvement of [i]microRNA-34a[/i] in Age-Related Susceptibility to Oxidative Stress in ARPE-19 Cells by Targeting the Silent Mating Type Information Regulation 2 Homolog 1/p66shc Pathway: Implications for Age-Related Macular Degeneration. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31249522 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584679 }} * {{medline-title |title=[[GPR39]] agonist TC-G 1008 ameliorates IL-1β-induced chondrocyte senescence. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31237151 |full-text-url=https://sci-hub.do/10.1080/21691401.2019.1626405 }} * {{medline-title |title=Rational design of novel sirtuin 1 activators via structure-activity insights from application of QSAR modeling. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31217784 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558509 }} * {{medline-title |title=Metformin prevents murine ovarian aging. |date=10.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182682 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594816 }} * {{medline-title |title=Time-restricted feeding delays the emergence of the age-associated, neoplastic-prone tissue landscape. |date=12.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188781 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594823 }} * {{medline-title |title=Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/[[SIRT1]] pathway. |date=10.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182679 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594820 }} * {{medline-title |title=[[SIRT1]] protects cochlear hair cell and delays age-related hearing loss via autophagy. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31170533 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.04.003 }} * {{medline-title |title=Transcriptome analysis revealed potential mechanisms of differences in physiological stress responses between caged male and female magpies. |date=03.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31159743 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547487 }} * {{medline-title |title=Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31144244 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885080 }} * {{medline-title |title=Molecular docking analysis of imine stilbene analogs and evaluation of their anti-aging activity using yeast and mammalian cell models. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31132911 |full-text-url=https://sci-hub.do/10.1080/10799893.2019.1605529 }} * {{medline-title |title=Molecular and Cellular Characterization of [[SIRT1]] Allosteric Activators. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31087296 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567996 }} * {{medline-title |title=Total flavonoids from the Carya cathayensis Sarg. leaves inhibit HUVEC senescence through the miR-34a/[[SIRT1]] pathway. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31106472 |full-text-url=https://sci-hub.do/10.1002/jcb.28986 }} * {{medline-title |title=Impaired [[SIRT1]] activity leads to diminution in glomerular endowment without accelerating age-associated GFR decline. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31087539 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513772 }} * {{medline-title |title=Estrogen-[[SIRT1]] Axis Plays a Pivotal Role in Protecting Arteries Against Menopause-Induced Senescence and Atherosclerosis. |date=01.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31105126 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976724 }} * {{medline-title |title=Spatio-temporal expression profile of sirtuins during aging of the annual fish Nothobranchius furzeri. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31075496 |full-text-url=https://sci-hub.do/10.1016/j.gep.2019.05.001 }} * {{medline-title |title=Protective effect of vildagliptin on [[TNF]]-α-induced chondrocyte senescence. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026379 |full-text-url=https://sci-hub.do/10.1002/iub.2049 }} * {{medline-title |title=Polymorphism rs7895833 in the [[SIRT1]] gene and its association with dyslipidaemia in the elderly. |date=07-08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31040057 |full-text-url=https://sci-hub.do/10.1016/j.regg.2019.01.008 }} * {{medline-title |title=Modulation of miR-34a/[[SIRT1]] signaling protects cochlear hair cells against oxidative stress and delays age-related hearing loss through coordinated regulation of mitophagy and mitochondrial biogenesis. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026620 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.03.013 }} * {{medline-title |title=Nicotinamide mononucleotide promotes osteogenesis and reduces adipogenesis by regulating mesenchymal stromal cells via the [[SIRT1]] pathway in aged bone marrow. |date=18.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31000692 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472410 }} * {{medline-title |title=Cordycepin, an Active Constituent of Nutrient Powerhouse and Potential Medicinal Mushroom [i]Cordyceps militaris[/i] Linn., Ameliorates Age-Related Testicular Dysfunction in Rats. |date=23.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31018574 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520895 }} * {{medline-title |title=The resistant effect of [[SIRT1]] in oxidative stress-induced senescence of rat nucleus pulposus cell is regulated by Akt-FoxO1 pathway. |date=31.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30967498 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509061 }} * {{medline-title |title=Photobiomodulation and Coenzyme Q Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30983970 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434313 }} * {{medline-title |title=The role of [[SIRT1]] in neuroinflammation and cognitive dysfunction in aged rats after anesthesia and surgery. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30972182 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456566 }} * {{medline-title |title=NAD supplementation rejuvenates aged gut adult stem cells. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30917412 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516145 }} * {{medline-title |title=[[NMNAT2]]-mediated NAD generation is essential for quality control of aged oocytes. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30909324 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516161 }} * {{medline-title |title=Mitochondrial dysfunction in neurodegenerative diseases and the potential countermeasure. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30889315 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566063 }} * {{medline-title |title=Drugs targeting [[SIRT1]], a new generation of therapeutics for osteoporosis and other bone related disorders? |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862606 |full-text-url=https://sci-hub.do/10.1016/j.phrs.2019.03.007 }} * {{medline-title |title=Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks. |date=11.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862067 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429360 }} * {{medline-title |title=Knockout of receptor for advanced glycation end-products attenuates age-related renal lesions. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30794349 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413655 }} * {{medline-title |title=Stress-induced precocious aging in PD-patient iPSC-derived NSCs may underlie the pathophysiology of Parkinson's disease. |date=04.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30718471 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362163 }} * {{medline-title |title=Bone Marrow Mesenchymal Stem Cells-Derived Exosomal MiR-29b-3p Regulates Aging-Associated Insulin Resistance. |date=26.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30715852 |full-text-url=https://sci-hub.do/10.1021/acsnano.8b09375 }} * {{medline-title |title=Strength training and aerobic exercise alter mitochondrial parameters in brown adipose tissue and equally reduce body adiposity in aged rats. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30712161 |full-text-url=https://sci-hub.do/10.1007/s13105-019-00663-x }} * {{medline-title |title=Novel biomolecules of ageing, sex differences and potential underlying mechanisms of telomere shortening in coronary artery disease. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30684534 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.020 }} * {{medline-title |title=Generation of a novel model of primary human cell senescence through Tenovin-6 mediated inhibition of sirtuins. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30666570 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535423 }} * {{medline-title |title=Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30659954 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.016 }} * {{medline-title |title=Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism. |date=23.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30673631 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366955 }} * {{medline-title |title=Protective Role of Endogenous Kallistatin in Vascular Injury and Senescence by Inhibiting Oxidative Stress and Inflammation. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30622668 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304815 }} * {{medline-title |title=NKT-like cells reveal higher than T lymphocytes expression of cellular protective proteins HSP70 and [[SOD2]] and comparably increased expression of [[SIRT1]] in the oldest seniors. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30633320 |full-text-url=https://sci-hub.do/10.5603/FHC.a2018.0025 }} * {{medline-title |title=Melatonin regulates the activities of ovary and delays the fertility decline in female animals via MT1/AMPK pathway. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30597622 |full-text-url=https://sci-hub.do/10.1111/jpi.12550 }} * {{medline-title |title=Exercise training augments Sirt1-signaling and attenuates cardiac inflammation in D-galactose induced-aging rats. |date=23.12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30582744 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326662 }} * {{medline-title |title=Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30537739 |full-text-url=https://sci-hub.do/10.1159/000495895 }} * {{medline-title |title=Diesel exhaust exposure intensifies inflammatory and structural changes associated with lung aging in mice. |date=15.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30530184 |full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.11.139 }} * {{medline-title |title=CD56bright cells respond to stimulation until very advanced age revealing increased expression of cellular protective proteins [[SIRT1]], HSP70 and [[SOD2]]. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30534181 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262966 }} * {{medline-title |title=Amentoflavone Induces Autophagy and Modulates p53. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30507085 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275431 }} * {{medline-title |title=Induction of a senescent like phenotype and loss of gap junctional intercellular communication by carbon nanoparticle exposure of lung epithelial cells. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30476532 |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.017 }} * {{medline-title |title=Sirtuins: Developing Innovative Treatments for Aged-Related Memory Loss and Alzheimer's Disease. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30484407 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538488 }} * {{medline-title |title=N-acetylcysteine ameliorates cisplatin-induced renal senescence and renal interstitial fibrosis through sirtuin1 activation and p53 deacetylation. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30447351 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.11.006 }} * {{medline-title |title=Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice. |date=20.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463018 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296764 }} * {{medline-title |title=Metformin Is a Direct [[SIRT1]]-Activating Compound: Computational Modeling and Experimental Validation. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30459716 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232372 }} * {{medline-title |title=Hsp90 Stabilizes [[SIRT1]] Orthologs in Mammalian Cells and [i]C. elegans[/i]. |date=20.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463299 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274930 }} * {{medline-title |title=Sirtuins and NAD in the Development and Treatment of Metabolic and Cardiovascular Diseases. |date=14.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30355082 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206880 }} * {{medline-title |title=[[SIRT1]] deacetylase in aging-induced neuromuscular degeneration and amyotrophic lateral sclerosis. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30295421 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260920 }} * {{medline-title |title=Prevention of Senescence in Vasculature Through Quiescence. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30259779 |full-text-url=https://sci-hub.do/10.1089/rej.2018.2138 }} * {{medline-title |title=Melatonin and inflammation-Story of a double-edged blade. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30242884 |full-text-url=https://sci-hub.do/10.1111/jpi.12525 }} * {{medline-title |title=[[ALDH2]] mediates the dose-response protection of chronic ethanol against endothelial senescence through [[SIRT1]]/p53 pathway. |date=12.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217444 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.08.081 }} * {{medline-title |title=Resveratrol-loaded nanoemulsion prevents cognitive decline after abdominal surgery in aged rats. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30196020 |full-text-url=https://sci-hub.do/10.1016/j.jphs.2018.08.006 }} * {{medline-title |title=Endothelial [[SIRT1]] prevents age-induced impairment of vasodilator responses by enhancing the expression and activity of soluble guanylyl cyclase in smooth muscle cells. |date=01.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30165439 |full-text-url=https://sci-hub.do/10.1093/cvr/cvy212 }} * {{medline-title |title=Effects of Ginsenoside Rg3 on fatigue resistance and [[SIRT1]] in aged rats. |date=01.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30144466 |full-text-url=https://sci-hub.do/10.1016/j.tox.2018.08.010 }} * {{medline-title |title=[[PARP1]] inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD levels and increasing [[SIRT1]] activity. |date=23.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30139380 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107962 }} * {{medline-title |title=Moderate calorie restriction attenuates age‑associated alterations and improves cardiac function by increasing [[SIRT1]] and [[SIRT3]] expression. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30132522 |full-text-url=https://sci-hub.do/10.3892/mmr.2018.9390 }} * {{medline-title |title=Liver regeneration in aged mice: new insights. |date=28.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30157472 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128415 }} * {{medline-title |title=Phenolic Plant Extracts Induce Sirt1 Activity and Increase Antioxidant Levels in the Rabbit's Heart and Liver. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30116475 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079382 }} * {{medline-title |title=Defect of [[SIRT1]]-FoxO3a axis is associated with the production of reactive oxygen species during protein kinase CK2 downregulation-mediated cellular senescence and nematode aging. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30103847 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507845 }} * {{medline-title |title=Master athletes have higher miR-7, [[SIRT3]] and [[SOD2]] expression in skeletal muscle than age-matched sedentary controls. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30107294 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092475 }} * {{medline-title |title=Tenovin-1 Induces Senescence and Decreases Wound-Healing Activity in Cultured Rat Primary Astrocytes. |date=01.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30092626 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513186 }} * {{medline-title |title=[[PGC]]-1α Protects [[RPE]] Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis. |date=07.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30087287 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121367 }} * {{medline-title |title=Effect of oral appliance on circulating leukocyte telomere length and [[SIRT1]] in obstructive sleep apnea. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30030618 |full-text-url=https://sci-hub.do/10.1007/s00784-018-2560-5 }} * {{medline-title |title=miR-34a Promotes Vascular Smooth Muscle Cell Calcification by Downregulating [[SIRT1]] (Sirtuin 1) and Axl (AXL Receptor Tyrosine Kinase). |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30026277 |full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.311298 }} * {{medline-title |title=A [[SIRT1]]-centered circuitry regulates breast cancer stemness and metastasis. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30038266 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283862 }} * {{medline-title |title=Apelin/APJ axis improves angiotensin II-induced endothelial cell senescence through AMPK/[[SIRT1]] signaling pathway. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30002688 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040122 }} * {{medline-title |title=Sirtuin 1 and Alzheimer's disease: An up-to-date review. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30007474 |full-text-url=https://sci-hub.do/10.1016/j.npep.2018.07.001 }} * {{medline-title |title=CCAR-1 is a negative regulator of the heat-shock response in Caenorhabditis elegans. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003683 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156500 }} * {{medline-title |title=Kallistatin attenuates endothelial senescence by modulating Let-7g-mediated miR-34a-[[SIRT1]]-eNOS pathway. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29992759 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111868 }} * {{medline-title |title=Serum containing Buyang Huanwu decoction prevents age-associated migration and invasion of human vascular smooth muscle cells by up regulating [[SIRT1]] expression. |date=17.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29952352 |full-text-url=https://sci-hub.do/10.5582/bst.2018.01063 }} * {{medline-title |title=Role of accelerated aging in limb muscle wasting of patients with COPD. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29970961 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022820 }} * {{medline-title |title=Resveratrol promotes oxidative stress to drive [[DLC1]] mediated cellular senescence in cancer cells. |date=15.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29964052 |full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.06.031 }} * {{medline-title |title=Mesenchymal stem cells confer resistance to doxorubicin-induced cardiac senescence by inhibiting microRNA-34a. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29928373 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004710 }} * {{medline-title |title=The circadian clock in adult neural stem cell maintenance. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29886147 |full-text-url=https://sci-hub.do/10.1016/j.pneurobio.2018.05.007 }} * {{medline-title |title=Resveratrol reduces senescence-associated secretory phenotype by [[SIRT1]]/NF-κB pathway in gut of the annual fish Nothobranchius guentheri. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29908321 |full-text-url=https://sci-hub.do/10.1016/j.fsi.2018.06.027 }} * {{medline-title |title=Loss of [[NAMPT]] in aging retinal pigment epithelium reduces NAD availability and promotes cellular senescence. |date=12.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905535 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046249 }} * {{medline-title |title=Mushroom extract inhibits ultraviolet B-induced cellular senescence in human keratinocytes. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29860669 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021292 }} * {{medline-title |title=[[SIRT1]], miR-132 and miR-212 link human longevity to Alzheimer's Disease. |date=31.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29855513 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981646 }} * {{medline-title |title=Endothelial progenitor cells from aged subjects display decreased expression of sirtuin 1, angiogenic functions, and increased senescence. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29851177 |full-text-url=https://sci-hub.do/10.1002/cbin.10999 }} * {{medline-title |title=Rejuvenating Aged Hematopoietic Stem Cells Through Improvement of Mitochondrial Function. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29797808 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973912 }} * {{medline-title |title=Berberine Improves Cognitive Deficiency and Muscular Dysfunction via Activation of the AMPK/[[SIRT1]]/[[PGC]]-1a Pathway in Skeletal Muscle from Naturally Aging Rats. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29806860 |full-text-url=https://sci-hub.do/10.1007/s12603-018-1015-7 }} * {{medline-title |title=[[SIRT1]] reverses senescence via enhancing autophagy and attenuates oxidative stress-induced apoptosis through promoting p53 degradation. |date=01.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29803744 |full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2018.05.174 }} * {{medline-title |title=Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774638 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052398 }} * {{medline-title |title=Dietary polyphenols and neurogenesis: Molecular interactions and implication for brain ageing and cognition. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29753753 |full-text-url=https://sci-hub.do/10.1016/j.neubiorev.2018.05.011 }} * {{medline-title |title=Whey Protein Attenuates Angiotensin II-Primed Premature Senescence of Vascular Smooth Muscle Cells through Upregulation of [[SIRT1]]. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29725214 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932937 }} * {{medline-title |title=Role of hypothalamus in aging and its underlying cellular mechanisms. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29729230 |full-text-url=https://sci-hub.do/10.1016/j.mad.2018.04.008 }} * {{medline-title |title=The variable role of [[SIRT1]] in the maintenance and differentiation of mesenchymal stem cells. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29715067 |full-text-url=https://sci-hub.do/10.2217/rme-2017-0128 }} * {{medline-title |title=Sirtuins in Renal Health and Disease. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29712732 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050939 }} * {{medline-title |title=Physical Exercise Improves Aging-Related Changes in Angiotensin, IGF-1, [[SIRT1]], [[SIRT3]], and VEGF in the Substantia Nigra. |date=10.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659739 |full-text-url=https://sci-hub.do/10.1093/gerona/gly072 }} * {{medline-title |title=MeCP2-mediated epigenetic regulation in senescent endothelial progenitor cells. |date=03.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615114 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883541 }} * {{medline-title |title=Natural products with anti-aging potential: Affected targets and molecular mechanisms. |date=01.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29597027 |full-text-url=https://sci-hub.do/10.1016/j.biotechadv.2018.03.012 }} * {{medline-title |title=[Effect of microRNA-34a/[[SIRT1]]/p53 signal pathway on notoginsenoside R₁ delaying vascular endothelial cell senescence]. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29600625 |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180110.001 }} * {{medline-title |title=[[SIRT1]] and microRNAs: The role in breast, lung and prostate cancers. |date=01.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29574020 |full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.03.023 }} * {{medline-title |title=Leukotriene D4 induces cellular senescence in osteoblasts. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29587204 |full-text-url=https://sci-hub.do/10.1016/j.intimp.2017.12.027 }} * {{medline-title |title=Impairment of an Endothelial NAD -H S Signaling Network Is a Reversible Cause of Vascular Aging. |date=22.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570999 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884172 }} * {{medline-title |title=Differential gene expression of sirtuins between somatotropinomas and nonfunctioning pituitary adenomas. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29564694 |full-text-url=https://sci-hub.do/10.1007/s11102-018-0881-7 }} * {{medline-title |title=Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice. |date=06.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29514072 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854409 }} * {{medline-title |title=Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29476819 |full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.004 }} * {{medline-title |title=[[HGF]] and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the [[SIRT1]]/[[FOXO1]] Signaling Pathway. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29462806 |full-text-url=https://sci-hub.do/10.1159/000487559 }} * {{medline-title |title=The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29407880 |full-text-url=https://sci-hub.do/10.1016/j.atherosclerosis.2018.01.043 }} * {{medline-title |title=Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29366775 |full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.01.018 }} * {{medline-title |title=Antagonism of cysteinyl leukotriene receptor 1 (cysLTR1) by montelukast suppresses cell senescence of chondrocytes. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29331588 |full-text-url=https://sci-hub.do/10.1016/j.cyto.2017.12.021 }} * {{medline-title |title=Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress. |date=20.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325896 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.01.007 }} * {{medline-title |title=Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury. |date=11.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29326403 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811244 }} * {{medline-title |title=Acetylshikonin from Zicao attenuates cognitive impairment and hippocampus senescence in d-galactose-induced aging mouse model via upregulating the expression of [[SIRT1]]. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325995 |full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2018.01.007 }} * {{medline-title |title=Dexamethasone downregulates [[SIRT1]] and [[IL6]] and upregulates [[EDN1]] genes in stem cells derived from gingivae via the AGE/RAGE pathway. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29302812 |full-text-url=https://sci-hub.do/10.1007/s10529-017-2493-0 }} * {{medline-title |title=Sirtuins in Brain Aging and Neurological Disorders. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29283326 |full-text-url=https://sci-hub.do/10.1615/CritRevEukaryotGeneExpr.2017019532 }} * {{medline-title |title=[Aging-related change of erectile function and the expression of [[SIRT1]]]. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29282911 }} * {{medline-title |title=Expression of Sirtuins in the Retinal Neurons of Mice, Rats, and Humans. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29249955 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715387 }} * {{medline-title |title=Maternal aging affects oocyte resilience to carbonyl cyanide-m-chlorophenylhydrazone -induced mitochondrial dysfunction in cows. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29182624 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705080 }} * {{medline-title |title=Nicotinamide phosphoribosyltransferase delays cellular senescence by upregulating [[SIRT1]] activity and antioxidant gene expression in mouse cells. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29178516 |full-text-url=https://sci-hub.do/10.1111/gtc.12542 }} * {{medline-title |title=Stem Cells and Progenitors in Human Peripheral Blood Get Activated by Extremely Active Resveratrol (XAR™). |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177909 |full-text-url=https://sci-hub.do/10.1007/s12015-017-9784-7 }} * {{medline-title |title=Fibroblast growth factor 21 delayed endothelial replicative senescence and protected cells from H O -induced premature senescence through [[SIRT1]]. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29118911 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666058 }} * {{medline-title |title=Tucum-do-Cerrado (Bactris setosa Mart.) May Promote Anti-Aging Effect by Upregulating [[SIRT1]]-Nrf2 Pathway and Attenuating Oxidative Stress and Inflammation. |date=14.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135935 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707715 }} * {{medline-title |title=Maternal high calorie diet induces mitochondrial dysfunction and senescence phenotype in subcutaneous fat of newborn mice. |date=13.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29137352 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663524 }} * {{medline-title |title=O-GlcNAcylation of [[SIRT1]] enhances its deacetylase activity and promotes cytoprotection under stress. |date=14.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29133780 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684413 }} * {{medline-title |title=Aging as an Epigenetic Phenomenon. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081695 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635645 }} * {{medline-title |title=MeCP2 mediated dysfunction in senescent EPCs. |date=03.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29108229 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667962 }} * {{medline-title |title=Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063982 |full-text-url=https://sci-hub.do/10.1007/s10571-017-0557-2 }} * {{medline-title |title=A comparative study of anti-aging properties and mechanism: resveratrol and caloric restriction. |date=12.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29029466 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630366 }} * {{medline-title |title=Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence. |date=17.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29041897 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645932 }} * {{medline-title |title=Negative regulation of Sirtuin 1 by AMP-activated protein kinase promotes metformin-induced senescence in hepatocellular carcinoma xenografts. |date=28.12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28964787 |full-text-url=https://sci-hub.do/10.1016/j.canlet.2017.09.027 }} * {{medline-title |title=Blocking [[SIRT1]] inhibits cell proliferation and promotes aging through the PI3K/AKT pathway. |date=01.12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28962864 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2017.09.037 }} * {{medline-title |title=[[SIRT1]] is a positive regulator of in vivo bone mass and a therapeutic target for osteoporosis. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28937996 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609767 }} * {{medline-title |title=[Protective effect of total saponins of Panax notoginseng combined with total flavonoids of epimedium on D-galactose-incuced senescence of H9c2 cell]. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28952264 |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.2017.0012 }} * {{medline-title |title=[[SIRT1]] is a transcriptional enhancer of the glucocorticoid receptor acting independently to its deacetylase activity. |date=05.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28923345 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756502 }} * {{medline-title |title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. |date=15.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352 }} * {{medline-title |title=The effect of exercise, resveratrol or their combination on Sarcopenia in aged rats via regulation of AMPK/Sirt1 pathway. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847722 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.032 }} * {{medline-title |title=Chronic Silymarin, Quercetin and Naringenin Treatments Increase Monoamines Synthesis and Hippocampal Sirt1 Levels Improving Cognition in Aged Rats. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28808887 |full-text-url=https://sci-hub.do/10.1007/s11481-017-9759-0 }} * {{medline-title |title=Aquatide Activation of [[SIRT1]] Reduces Cellular Senescence through a [[SIRT1]]-[[FOXO1]]-Autophagy Axis. |date=01.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28822991 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590795 }} * {{medline-title |title=Obesity and aging diminish sirtuin 1 ([[SIRT1]])-mediated deacetylation of [[SIRT3]], leading to hyperacetylation and decreased activity and stability of [[SIRT3]]. |date=20.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28808064 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655509 }} * {{medline-title |title=Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging. |date=10.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28802039 |full-text-url=https://sci-hub.do/10.1016/j.cell.2017.07.042 }} * {{medline-title |title=High glucose and free fatty acids induce endothelial progenitor cell senescence via [[PGC]]-1α/[[SIRT1]] signaling pathway. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28786152 |full-text-url=https://sci-hub.do/10.1002/cbin.10833 }} * {{medline-title |title=Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28767699 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540417 }} * {{medline-title |title=Comparing the Effects of Melatonin with Caloric Restriction in the Hippocampus of Aging Mice: Involvement of Sirtuin1 and the FOXOs Pathway. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28770437 |full-text-url=https://sci-hub.do/10.1007/s11064-017-2369-7 }} * {{medline-title |title=Role of Kallistatin Treatment in Aging and Cancer by Modulating miR-34a and miR-21 Expression. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28744338 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506461 }} * {{medline-title |title=Inflammation, Stem Cells, and the Aging Hypothalamus. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28756738 |full-text-url=https://sci-hub.do/10.1089/rej.2017.2002 }} * {{medline-title |title=Myricetin improves endurance capacity and mitochondrial density by activating [[SIRT1]] and [[PGC]]-1α. |date=24.07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28740165 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524912 }} * {{medline-title |title=Moving to the Rhythm with Clock (Circadian) Genes, Autophagy, mTOR, and [[SIRT1]] in Degenerative Disease and Cancer. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28721811 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600856 }} * {{medline-title |title=The emerging role of alternative splicing in senescence and aging. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28703423 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595669 }} * {{medline-title |title=miR-34a and miR-9 are overexpressed and SIRT genes are downregulated in peripheral blood mononuclear cells of aging humans. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28699360 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544174 }} * {{medline-title |title=Regulation of [[SIRT1]]/AMPK axis is critically involved in gallotannin-induced senescence and impaired autophagy leading to cell death in hepatocellular carcinoma cells. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676953 |full-text-url=https://sci-hub.do/10.1007/s00204-017-2021-y }} * {{medline-title |title=[[SIRT1]] and [[SIRT6]] Signaling Pathways in Cardiovascular Disease Protection. |date=10.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28661724 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824538 }} * {{medline-title |title=Effects of Resveratrol and other Polyphenols on Sirt1: Relevance to Brain Function During Aging. |date=30.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676015 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883375 }} * {{medline-title |title=Reduction in podocyte [[SIRT1]] accelerates kidney injury in aging mice. |date=01.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28615249 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625108 }} * {{medline-title |title=Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs. |date=12.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28611316 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509453 }} * {{medline-title |title=Ursolic Acid Mediates Hepatic Protection through Enhancing of anti-aging Biomarkers. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28558631 |full-text-url=https://sci-hub.do/10.2174/1874609810666170531103140 }} * {{medline-title |title=The NAD /[[PARP1]]/[[SIRT1]] Axis in Aging. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28537485 |full-text-url=https://sci-hub.do/10.1089/rej.2017.1980 }} * {{medline-title |title=Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28552621 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581719 }} * {{medline-title |title=Kallistatin reduces vascular senescence and aging by regulating microRNA-34a-[[SIRT1]] pathway. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28544111 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506400 }} * {{medline-title |title=Bushen-Yizhi formula ameliorates cognitive dysfunction through [[SIRT1]]/ER stress pathway in SAMP8 mice. |date=25.07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28521305 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564772 }} * {{medline-title |title=Caveolin-1 deficiency induces premature senescence with mitochondrial dysfunction. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28514055 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506423 }} * {{medline-title |title=Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-[[FOXO1]] pathway. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28507478 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427465 }} * {{medline-title |title=Steroidogenesis decline accompanied with reduced antioxidation and endoplasmic reticulum stress in mice testes during ageing. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28488286 |full-text-url=https://sci-hub.do/10.1111/and.12816 }} * {{medline-title |title=Exogenous nicotinamide supplementation and moderate physical exercise can attenuate the aging process in skeletal muscle of rats. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28477081 |full-text-url=https://sci-hub.do/10.1007/s10522-017-9705-9 }} * {{medline-title |title=Caloric restriction delays early phases of carcinogenesis via effects on the tissue microenvironment. |date=30.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28415598 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482635 }} * {{medline-title |title=During yeast chronological aging resveratrol supplementation results in a short-lived phenotype Sir2-dependent. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28412652 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397018 }} * {{medline-title |title=Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts. |date=01.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28385812 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495944 }} * {{medline-title |title=Regulation of stem cell aging by [[SIRT1]] - Linking metabolic signaling to epigenetic modifications. |date=05.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28392411 |full-text-url=https://sci-hub.do/10.1016/j.mce.2017.03.031 }} * {{medline-title |title=Ampelopsin attenuates the atrophy of skeletal muscle from d-gal-induced aging rats through activating AMPK/[[SIRT1]]/PGC-1α signaling cascade. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28364603 |full-text-url=https://sci-hub.do/10.1016/j.biopha.2017.03.070 }} * {{medline-title |title=[[SIRT1]] Polymorphisms and Serum-Induced [[SIRT1]] Protein Expression in Aging and Frailty: The CHAMP Study. |date=01.07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28329314 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279142 }} * {{medline-title |title=Melatonin reverses H O -induced senescence in SH-SY5Y cells by enhancing autophagy via sirtuin 1 deacetylation of the RelA/p65 subunit of NF-κB. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28295567 |full-text-url=https://sci-hub.do/10.1111/jpi.12407 }} * {{medline-title |title=Alkylresorcinols activate [[SIRT1]] and delay ageing in Drosophila melanogaster. |date=02.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28252007 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333101 }} * {{medline-title |title=Tat-Mediated Induction of miRs-34a
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