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Aging genes 10-29
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__NOTOC__ * [[Aging genes 100|Genes with 100 and more publications]] * [[Aging genes 60-99|Genes with 60-99 publications]] * [[Aging genes 30-59|Genes with 30-59 publications]] * [[Aging genes 10-29|Genes with 10-29 publications]] * [[Aging genes 3-9|Genes with 3-9 publications]] * [[Aging genes 1-2|Genes with 1-2 publications]] ==CCL2== * {{medline-title |title=β1 Integrin regulates adult lung alveolar epithelial cell inflammation. |date=30.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31873073 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098727 }} * {{medline-title |title=Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872008 |full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.03.004 }} * {{medline-title |title=Membrane metallo-endopeptidase mediates cellular senescence induced by oncogenic [[PIK3CA]] accompanied with pro-tumorigenic secretome. |date=01.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30671946 |full-text-url=https://sci-hub.do/10.1002/ijc.32153 }} * {{medline-title |title=Isoflurane anesthesia impairs the expression of immune neuromodulators in the hippocampus of aged mice. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30571762 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301699 }} * {{medline-title |title=Melatonin and inflammation-Story of a double-edged blade. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30242884 |full-text-url=https://sci-hub.do/10.1111/jpi.12525 }} * {{medline-title |title=Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025494 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152523 }} * {{medline-title |title=Urine Cytokine and Chemokine Levels Predict Urinary Tract Infection Severity Independent of Uropathogen, Urine Bacterial Burden, Host Genetics, and Host Age. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891542 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105902 }} * {{medline-title |title=Infiltrating macrophages contribute to age-related neuroinflammation in C57/BL6 mice. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29758231 |full-text-url=https://sci-hub.do/10.1016/j.mad.2018.05.003 }} * {{medline-title |title=Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound Aging of Skeletal Muscles. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760352 |full-text-url=https://sci-hub.do/10.1620/tjem.245.29 }} * {{medline-title |title=Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487806 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824071 }} * {{medline-title |title=Immune senescence and biomarkers profile of Bambuí aged population-based cohort. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29247791 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.12.006 }} * {{medline-title |title=Selected life-extending interventions reduce arterial [[CXCL10]] and macrophage colony-stimulating factor in aged mouse arteries. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28390264 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544385 }} * {{medline-title |title=Strain specificities in cellular and molecular immunopathogenic mechanisms underlying development of experimental autoimmune encephalomyelitis in aged rats. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28284714 |full-text-url=https://sci-hub.do/10.1016/j.mad.2017.03.001 }} * {{medline-title |title=Advanced atherosclerosis is associated with inflammation, vascular dysfunction and oxidative stress, but not hypertension. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28017665 |full-text-url=https://sci-hub.do/10.1016/j.phrs.2016.12.032 }} * {{medline-title |title=An attenuated immune response by Schwann cells and macrophages inhibits nerve regeneration in aged rats. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27459920 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2016.05.004 }} * {{medline-title |title=Enhanced Ccl2-Ccr2 signaling drives more severe choroidal neovascularization with aging. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26973110 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2015.12.019 }} * {{medline-title |title=Agmatine Ameliorates High Glucose-Induced Neuronal Cell Senescence by Regulating the p21 and p53 Signaling. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26924930 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766111 }} * {{medline-title |title=Alterations in Monocyte Phenotypes and Functions after a Hip Fracture in Elderly Individuals: A 6-Month Longitudinal Study. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26812523 |full-text-url=https://sci-hub.do/10.1159/000443142 }} * {{medline-title |title=Elevated Levels of Microbial Translocation Markers and [[CCL2]] Among Older HIV-1-Infected Men. |date=01.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26494772 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747622 }} * {{medline-title |title=[[APOE]] Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration. |date=07.10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26446211 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605380 }} * {{medline-title |title=Colorectal cancer-promoting activity of the senescent peritoneal mesothelium. |date=06.10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26284488 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745719 }} * {{medline-title |title=Nilotinib and bosutinib modulate pre-plaque alterations of blood immune markers and neuro-inflammation in Alzheimer's disease models. |date=24.09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26235435 |full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2015.07.070 }} * {{medline-title |title=Neuroimmune and Neuropathic Responses of Spinal Cord and Dorsal Root Ganglia in Middle Age. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26241743 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524632 }} * {{medline-title |title=Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26011191 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444306 }} * {{medline-title |title=[[CCL2]], [[CXCL8]], [[CXCL9]] and [[CXCL10]] serum levels increase with age but are not altered by treatment with hydroxychloroquine in patients with osteoarthritis of the knees. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25955863 |full-text-url=https://sci-hub.do/10.1111/1756-185X.12589 }} * {{medline-title |title=Senescent dermal fibroblasts enhance stem cell migration through [[CCL2]]/C[[CR2]] axis. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25808810 |full-text-url=https://sci-hub.do/10.1111/exd.12701 }} * {{medline-title |title=Age-associated changes in basal NF-κB function in human CD4 T lymphocytes via dysregulation of PI3 kinase. |date=11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25553802 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276789 }} * {{medline-title |title=IL-4 signaling drives a unique arginase /IL-1β microglia phenotype and recruits macrophages to the inflammatory CNS: consequences of age-related deficits in IL-4Rα after traumatic spinal cord injury. |date=25.06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24966389 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069360 }} * {{medline-title |title=Systemic inflammation impairs attention and cognitive flexibility but not associative learning in aged rats: possible implications for delirium. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24959140 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050637 }} ==EGFR== * {{medline-title |title=Type I Collagen Aging Increases Expression and Activation of [[EGFR]] and Induces Resistance to Erlotinib in Lung Carcinoma in 3D Matrix Model. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33014812 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511549 }} * {{medline-title |title=Comparative effectiveness and cost-effectiveness of three first-line [[EGFR]]-tyrosine kinase inhibitors: Analysis of real-world data in a tertiary hospital in Taiwan. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32267879 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141611 }} * {{medline-title |title=An Optogenetic Method to Study Signal Transduction in Intestinal Stem Cell Homeostasis. |date=01.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32201167 |full-text-url=https://sci-hub.do/10.1016/j.jmb.2020.03.019 }} * {{medline-title |title=Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway. |date=13.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31935369 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146079 }} * {{medline-title |title=Association between [[EGFR]] mutation and ageing, history of pneumonia and gastroesophageal reflux disease among patients with advanced lung cancer. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31634646 |full-text-url=https://sci-hub.do/10.1016/j.ejca.2019.09.010 }} * {{medline-title |title=Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms. |date=22.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31332237 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646318 }} * {{medline-title |title=The role of [[EGFR]] signaling in age-related osteoporosis in mouse cortical bone. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298955 |full-text-url=https://sci-hub.do/10.1096/fj.201900436RR }} * {{medline-title |title=Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes. |date=13.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31200451 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627600 }} * {{medline-title |title=[[EGF]]/[[EGF]]R upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence. |date=04.12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30514230 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280426 }} * {{medline-title |title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574 |full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2 }} * {{medline-title |title=Quantum Modeling: A Bridge between the Pumping and Signaling Functions of Na/K-ATPase. |date=09.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30096926 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121303 }} * {{medline-title |title=Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer. |date=30.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29682186 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908287 }} * {{medline-title |title=Withanolide A extends the lifespan in human [[EGFR]]-driven cancerous Caenorhabditis elegans. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29427754 |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.02.004 }} * {{medline-title |title=30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Nongenomic effects via the mineralocorticoid receptor. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28348113 |full-text-url=https://sci-hub.do/10.1530/JOE-16-0659 }} * {{medline-title |title=Inverse relationship between Alzheimer's disease and cancer, and other factors contributing to Alzheimer's disease: a systematic review. |date=22.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27875990 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120447 }} * {{medline-title |title=Low-frequency [i]KRAS[/i] mutations are prevalent in lung adenocarcinomas. |date=03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27795727 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084916 }} * {{medline-title |title=Association of Polymorphisms in Connective Tissue Growth Factor and Epidermal Growth Factor Receptor Genes With Human Longevity. |date=01.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27365368 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861942 }} * {{medline-title |title=sPLA2 -IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induces Differentiation Mediated Through Enhanced JNK/c-Jun Activation. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27299855 |full-text-url=https://sci-hub.do/10.1002/stem.2418 }} * {{medline-title |title=Mechanisms of skin aging induced by [[EGFR]] inhibitors. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27165055 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611667 }} * {{medline-title |title=Prolactin, [[EGFR]], vimentin and α-actin profiles in elderly rat prostate subjected to steroid hormonal imbalance. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27021728 |full-text-url=https://sci-hub.do/10.1016/j.tice.2016.03.008 }} * {{medline-title |title=Loss of Maspardin Attenuates the Growth and Maturation of Mouse Cortical Neurons. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26978163 |full-text-url=https://sci-hub.do/10.1159/000443666 }} * {{medline-title |title=Expression profile analysis of new candidate genes for the therapy of primary osteoporosis. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26914116 }} * {{medline-title |title=Selective coexpression of V[[EGF]] receptor 2 in [[EGF]]RvIII-positive glioblastoma cells prevents cellular senescence and contributes to their aggressive nature. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26420897 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827039 }} * {{medline-title |title=Bradykinin inhibits oxidative stress-induced senescence of endothelial progenitor cells through the B2R/AKT/RB and B2R/[[EGFR]]/RB signal pathways. |date=22.09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26360782 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694787 }} * {{medline-title |title=First-line gefitinib treatment in elderly patients (aged ≥75 years) with non-small cell lung cancer harboring [[EGFR]] mutations. |date=10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26254024 |full-text-url=https://sci-hub.do/10.1007/s00280-015-2841-5 }} * {{medline-title |title=Increased centrosome amplification in aged stem cells of the Drosophila midgut. |date=25.07.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24971546 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2014.06.085 }} * {{medline-title |title=Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain. |date=07.05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24843006 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038845 }} * {{medline-title |title=Thiamin concentration in geriatric hospitalized patients using frusemide. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24597996 |full-text-url=https://sci-hub.do/10.1080/21551197.2013.875501 }} * {{medline-title |title=4-Hydroxynonenal impairs transforming growth factor-β1-induced elastin synthesis via epidermal growth factor receptor activation in human and murine fibroblasts. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24561579 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2014.02.015 }} ==LBP== * {{medline-title |title=Lipopolysaccharide binding protein is associated with CVD risk in older adults. |date=08.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32895891 |full-text-url=https://sci-hub.do/10.1007/s40520-020-01684-z }} * {{medline-title |title=Aging-related liver degeneration is associated with increased bacterial endotoxin and lipopolysaccharide binding protein levels. |date=01.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32090603 |full-text-url=https://sci-hub.do/10.1152/ajpgi.00345.2018 }} * {{medline-title |title=Biomarkers of leaky gut are related to inflammation and reduced physical function in older adults with cardiometabolic disease and mobility limitations. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31654268 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925090 }} * {{medline-title |title=Needle-shaped amyloid deposition in rat mammary gland: evidence of a novel amyloid fibril protein. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31615282 |full-text-url=https://sci-hub.do/10.1080/13506129.2019.1675623 }} * {{medline-title |title=Effects of Lycium barbarum Polysaccharides on Health and Aging of [i]C. elegans[/i] Depend on [i]daf-12/daf-16[/i]. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31583041 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754959 }} * {{medline-title |title=Structural characterization of life-extending Caenorhabditis elegans Lipid Binding Protein 8. |date=10.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292465 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620326 }} * {{medline-title |title=Lycium barbarum polysaccharides extend the mean lifespan of Drosophila melanogaster. |date=17.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31259337 |full-text-url=https://sci-hub.do/10.1039/c8fo01751d }} * {{medline-title |title=Height loss but not body composition is related to low back pain in community-dwelling elderlies: Shimane CoHRE study. |date=10.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31077175 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511157 }} * {{medline-title |title=Aging of mouse intervertebral disc and association with back pain. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30936040 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549718 }} * {{medline-title |title=A comparison of the mitochondrial proteome and lipidome in the mouse and long-lived Pipistrelle bats. |date=19.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30892277 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461166 }} * {{medline-title |title=Chen-Style Tai Chi for Individuals (Aged 50 Years Old or Above) with Chronic Non-Specific Low Back Pain: A Randomized Controlled Trial. |date=12.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30759778 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388249 }} * {{medline-title |title=Lysosomal Signaling Promotes Longevity by Adjusting Mitochondrial Activity. |date=11.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30713071 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613828 }} * {{medline-title |title=Factors associated with lumbar disc high-intensity zone (HIZ) on T2-weighted magnetic resonance image: a retrospective study of 3185 discs in 637 patients. |date=04.12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30514333 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280348 }} * {{medline-title |title=Urolithin A Inhibits the Catabolic Effect of TNFα on Nucleus Pulposus Cell and Alleviates Intervertebral Disc Degeneration [i]in vivo[/i]. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30283339 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157327 }} * {{medline-title |title=Use of trunk muscle training and neuromuscular electrical stimulation to reduce pain and disability in an older adult with chronic low back pain: A case report. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29617180 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179941 }} * {{medline-title |title=Endotoxemia is modulated by quantity and quality of dietary fat in older adults. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129737 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.006 }} * {{medline-title |title=Correlates of a Recent History of Disabling Low Back Pain in Community-dwelling Older Persons: The Pain in the Elderly (PAINEL) Study. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29077624 |full-text-url=https://sci-hub.do/10.1097/AJP.0000000000000564 }} * {{medline-title |title=The Effectiveness and Safety of Manual Therapy on Pain and Disability in Older Persons With Chronic Low Back Pain: A Systematic Review. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29079255 |full-text-url=https://sci-hub.do/10.1016/j.jmpt.2017.06.008 }} * {{medline-title |title=De-educate to re-educate: aging and low back pain. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28275956 |full-text-url=https://sci-hub.do/10.1007/s40520-017-0731-x }} * {{medline-title |title=Activity of Erector Spinae During Trunk Forward Bending and Backward Return: The Effects of Age. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28194659 |full-text-url=https://sci-hub.do/10.1007/s10439-017-1811-y }} * {{medline-title |title=Global Cysteine-Reactivity Profiling during Impaired Insulin/IGF-1 Signaling in C. elegans Identifies Uncharacterized Mediators of Longevity. |date=18.08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27499530 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003114 }} * {{medline-title |title=Age- and brain region-dependent α-synuclein oligomerization is attributed to alterations in intrinsic enzymes regulating α-synuclein phosphorylation in aging monkey brains. |date=23.02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27032368 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890980 }} * {{medline-title |title=Association of Lipopolysaccharide-Binding Protein With Aging-Related Adiposity Change and Prediabetes Among African Ancestry Men. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26721818 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764043 }} * {{medline-title |title=Age-related differences in trunk intrinsic stiffness. |date=11.04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26459489 |full-text-url=https://sci-hub.do/10.1016/j.jbiomech.2015.09.010 }} * {{medline-title |title=Probiotics Reduce Inflammation in Antiretroviral Treated, HIV-Infected Individuals: Results of the "Probio-HIV" Clinical Trial. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26376436 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573418 }} * {{medline-title |title=The effects of age and gender on the lumbopelvic rhythm in the sagittal plane in 309 subjects. |date=18.09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26294355 |full-text-url=https://sci-hub.do/10.1016/j.jbiomech.2015.07.030 }} * {{medline-title |title=Does physical activity moderate the relationship between depression symptomatology and low back pain? 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Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans. |date=02.01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25554789 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425353 }} * {{medline-title |title=Comparative study of human age estimation with or without preclassification of gender and facial expression. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25295308 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175379 }} ==LPA== * {{medline-title |title=Ginseng gintonin, aging societies, and geriatric brain diseases. |date=03.2021 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32817818 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426447 }} * {{medline-title |title=Late-life related subtypes of depression - a data-driven approach on cognitive domains and physical frailty. |date=22.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32442243 |full-text-url=https://sci-hub.do/10.1093/gerona/glaa110 }} * {{medline-title |title=Does sedentary time increase in older adults in the days following participation in intense exercise? |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32130714 |full-text-url=https://sci-hub.do/10.1007/s40520-020-01502-6 }} * {{medline-title |title=Association of Long-term Exposure to Elevated Lipoprotein(a) Levels With Parental Life Span, Chronic Disease-Free Survival, and Mortality Risk: A Mendelian Randomization Analysis. |date=05.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32108890 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049087 }} * {{medline-title |title=Elevated Autotaxin and [[LPA]] Levels During Chronic Viral Hepatitis and Hepatocellular Carcinoma Associate with Systemic Immune Activation. |date=25.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31769428 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966516 }} * {{medline-title |title=Lysophosphatidic acid receptor [[LPA]] prevents oxidative stress and cellular senescence in Hutchinson-Gilford progeria syndrome. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31714004 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974717 }} * {{medline-title |title=Associations of Sedentary and Physically-Active Behaviors With Cognitive-Function Decline in Community-Dwelling Older Adults: Compositional Data Analysis From the NEIGE Study. |date=05.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31656243 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557173 }} * {{medline-title |title=Validation and comparison of two automated methods for quantifying brain white matter hyperintensities of presumed vascular origin. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31612759 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607266 }} * {{medline-title |title=The Sedentary Time and Physical Activity Levels on Physical Fitness in the Elderly: A Comparative Cross Sectional Study. 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of Light-Intensity Physical Activity and Glucose Dynamics in Older Adults. |date=01.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526273 |full-text-url=https://sci-hub.do/10.1123/jpah.2017-0557 }} * {{medline-title |title=Accelerometer-Measured Physical Activity and Sedentary Behavior: A Cross-Sectional Study of Brazilian Older Adults. |date=01.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30336719 |full-text-url=https://sci-hub.do/10.1123/jpah.2017-0456 }} * {{medline-title |title=The Association Between Physical Activity, Including Physical Activity Intensity, and Fear of Falling Differs by Fear Severity in Older Adults Living in the Community. |date=16.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30219902 |full-text-url=https://sci-hub.do/10.1093/geronb/gby103 }} * {{medline-title |title=Gintonin Attenuates D-Galactose-Induced Hippocampal Senescence by Improving Long-Term Hippocampal Potentiation, Neurogenesis, and Cognitive Functions. |date=2018 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|full-text-url=https://sci-hub.do/10.1016/j.archger.2014.07.008 }} * {{medline-title |title=Inverse effects of midlife occupational and leisure time physical activity on mobility limitation in old age--a 28-year prospective follow-up study. |date=05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24731135 |full-text-url=https://sci-hub.do/10.1111/jgs.12793 }} ==NPY== * {{medline-title |title=Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells. |date=22.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32012215 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243588 }} * {{medline-title |title=Effects of rikkunshito supplementation on resistance to oxidative stress and lifespan in mice. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31855319 |full-text-url=https://sci-hub.do/10.1111/ggi.13848 }} * {{medline-title |title=Autophagy within the mushroom body protects from synapse aging in a non-cell autonomous manner. |date=21.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30899013 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428838 }} * {{medline-title |title=β-Alanine supplementation reduces anxiety and increases neurotrophin expression in both young and older rats. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30803507 |full-text-url=https://sci-hub.do/10.1016/j.nutres.2018.11.001 }} * {{medline-title |title=Age-related central regulation of orexin and [[NPY]] in the short-lived African killifish Nothobranchius furzeri. |date=15.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30666646 |full-text-url=https://sci-hub.do/10.1002/cne.24638 }} * {{medline-title |title=Chronic treatment with tributyltin induces sexually dimorphic alterations in the hypothalamic [[POMC]] system of adult mice. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30078105 |full-text-url=https://sci-hub.do/10.1007/s00441-018-2896-9 }} * {{medline-title |title=Expression of CGRP neurotransmitter and vascular genesis marker mRNA is age-dependent in superior cervical ganglia of senescence-accelerated prone mice. |date=18.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154859 |full-text-url=https://sci-hub.do/10.1016/j.neulet.2017.11.034 }} * {{medline-title |title=Comparing the Effects of Melatonin with Caloric Restriction in the Hippocampus of Aging Mice: Involvement of Sirtuin1 and the FOXOs Pathway. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28770437 |full-text-url=https://sci-hub.do/10.1007/s11064-017-2369-7 }} * {{medline-title |title=Bioactive growth hormone in older men and women: It's relationship to immune markers and healthspan. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28551577 |full-text-url=https://sci-hub.do/10.1016/j.ghir.2017.05.002 }} * {{medline-title |title=Retinal, [[NPY]]- and 5ht- inputs to the aged suprachiasmatic nucleus in common marmosets (Callithrix 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|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.09.017 }} * {{medline-title |title=Age Impaired endothelium-dependent vasodilation is improved by resveratrol in rat mesenteric arteries. |date=31.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27298812 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899900 }} * {{medline-title |title=Age-related changes in neurochemical components and retinal projections of rat intergeniculate leaflet. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26718202 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005876 }} * {{medline-title |title=Short photoperiod condition increases susceptibility to stress in adolescent male rats. |date=01.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26655789 |full-text-url=https://sci-hub.do/10.1016/j.bbr.2015.12.002 }} * {{medline-title |title=Neuropeptide Y: An Anti-Aging Player? |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26549884 |full-text-url=https://sci-hub.do/10.1016/j.tins.2015.08.012 }} * {{medline-title |title=Influence of Aging and Gender Differences on Feeding Behavior and Ghrelin-Related Factors during Social Isolation in Mice. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448274 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598162 }} * {{medline-title |title=Reduction in [[NPY]]-positive neurons and dysregulation of excitability in young senescence-accelerated mouse prone 8 (SAMP8) hippocampus precede the onset of cognitive impairment. |date=10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26250996 |full-text-url=https://sci-hub.do/10.1111/jnc.13274 }} * {{medline-title |title=Age effects on the nucleus of the lateral olfactory tract of the rat. |date=01.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26224652 |full-text-url=https://sci-hub.do/10.1002/cne.23863 }} * {{medline-title |title=[[NPY]]/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging? |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26086271 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590601 }} * {{medline-title |title=Analysis of gene expression during aging of CGNs in culture: implication of [[SLIT2]] and [[NPY]] in senescence. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26047956 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493715 }} * {{medline-title |title=Neuropeptide Y stimulates autophagy in hypothalamic neurons. |date=31.03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25775546 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386327 }} * {{medline-title |title=Effect of IP3R3 and [[NPY]] on age-related declines in olfactory stem cell proliferation. |date=02.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25482245 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315725 }} * {{medline-title |title=Old-onset caloric restriction effects on neuropeptide Y- and somatostatin-containing neurons and on cholinergic varicosities in the rat hippocampal formation. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25471895 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259091 }} * {{medline-title |title=Orally administered δ opioid agonist peptide rubiscolin-6 stimulates food intake in aged mice with ghrelin resistance. |date=10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25047666 |full-text-url=https://sci-hub.do/10.1002/mnfr.201400100 }} * {{medline-title |title=Ghrelin receptor regulates appetite and satiety during aging in mice by regulating meal frequency and portion size but not total food intake. |date=09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24991043 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130825 }} * {{medline-title |title=Distribution of peptidergic populations in the human dentate gyrus (somatostatin [SOM-28, SOM-12] and neuropeptide Y [[[NPY]]]) during postnatal development. 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|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009 |full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6 }} * {{medline-title |title=Effects of a resistance-training programme on endoplasmic reticulum unfolded protein response and mitochondrial functions in PBMCs from elderly subjects. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30614406 |full-text-url=https://sci-hub.do/10.1080/17461391.2018.1561950 }} * {{medline-title |title=[Protective effect of Wuzi Yanzong recipe on testicular germ cell apoptosis in natural ageing rats through endoplasmic reticulum stress]. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30453716 |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180530.001 }} * {{medline-title |title=Protective effect of Wuzi Yanzong recipe on testicular dysfunction through inhibition of germ cell apoptosis in ageing rats via endoplasmic reticulum stress. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30393883 |full-text-url=https://sci-hub.do/10.1111/and.13181 }} * {{medline-title |title=Loss of NRF-2 and [[PGC]]-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30253279 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156745 }} * {{medline-title |title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528 }} * {{medline-title |title=De-silencing [i]Grb10[/i] contributes to acute ER stress-induced steatosis in mouse liver. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29555819 |full-text-url=https://sci-hub.do/10.1530/JME-18-0018 }} * {{medline-title |title=Resveratrol modulates response against acute inflammatory stimuli in aged mouse brain. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29174969 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.014 }} * {{medline-title |title=Integrated stress response stimulates [[FGF21]] expression: Systemic enhancer of longevity. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28844867 |full-text-url=https://sci-hub.do/10.1016/j.cellsig.2017.08.009 }} * {{medline-title |title=Role of [[ATF4]] in skeletal muscle atrophy. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28376050 |full-text-url=https://sci-hub.do/10.1097/MCO.0000000000000362 }} * {{medline-title |title=4E-BP is a target of the GCN2-[[ATF4]] pathway during Drosophila development and aging. |date=02.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27979906 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|date=16.11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26467812 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679557 }} * {{medline-title |title=Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 ([[ATF4]])-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy. |date=16.10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26338703 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646196 }} * {{medline-title |title=Effect of mitochondrial stress on systemic metabolism. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26100439 |full-text-url=https://sci-hub.do/10.1111/nyas.12822 }} * {{medline-title |title=Senescence may mediate conversion of tau phosphorylation-induced apoptotic escape to neurodegeneration. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25777063 |full-text-url=https://sci-hub.do/10.1016/j.exger.2015.03.007 }} * {{medline-title |title=Impact of ER stress-regulated 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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32061977 |full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2020.110317 }} * {{medline-title |title=Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish. |date=03-04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31911208 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061078 }} * {{medline-title |title=Second generation effects of larval metal pollutant exposure on reproduction, longevity and insecticide tolerance in the major malaria vector Anopheles arabiensis (Diptera: Culicidae). |date=07.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31910892 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947826 }} * {{medline-title |title=Protective effect of Pedro-Ximénez must against p,p'-DDE-induced liver damages in aged Mus spretus mice. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31765701 |full-text-url=https://sci-hub.do/10.1016/j.fct.2019.110984 }} * {{medline-title |title=Low-dose endosulfan inhibits proliferation and induces senescence and pro-inflammatory cytokine production in human lymphocytes, preferentially impacting cytotoxic cells. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31589084 |full-text-url=https://sci-hub.do/10.1080/1547691X.2019.1668513 }} * {{medline-title |title=DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy. |date=22.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31251805 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698745 }} * {{medline-title |title=The contribution of gut bacteria to insecticide resistance and the life histories of the major malaria vector Anopheles arabiensis (Diptera: Culicidae). |date=24.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31235803 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591418 }} * {{medline-title |title=Exposure to the insecticide-treated bednet PermaNet 2.0 reduces the longevity of the wild African malaria vector Anopheles funestus but GSTe2-resistant mosquitoes live longer. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30870507 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417719 }} * {{medline-title |title=The occurrence and dynamics of polychlorinated hydrocarbons in roe deer ([i]Capreolus capreolus[/i]) in South-western Slovakia. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30729857 |full-text-url=https://sci-hub.do/10.1080/10934529.2019.1574152 }} * {{medline-title |title=Insecticide resistance status of three vectors of Japanese encephalitis in east central India. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30565276 |full-text-url=https://sci-hub.do/10.1111/mve.12352 }} * {{medline-title |title=Effect of aging on bioaccessibility of [[DDT]]s and PCBs in marine sediment. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30471469 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349416 }} * {{medline-title |title=The effect of commercial herbicide exposure on the life history and insecticide resistance phenotypes of the major malaria vector Anopheles arabiensis (Diptera: culicidae). |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30179608 |full-text-url=https://sci-hub.do/10.1016/j.actatropica.2018.08.030 }} * {{medline-title |title=Is Chronic Exposure to Low-Dose Organochlorine Pesticides a New Risk Factor of T-cell Immunosenescence? |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29991517 |full-text-url=https://sci-hub.do/10.1158/1055-9965.EPI-17-0799 }} * {{medline-title |title=The influence of age on insecticide susceptibility of Anopheles arabiensis during dry and rainy seasons in rice irrigation schemes of Northern Tanzania. |date=11.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28893240 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594483 }} * {{medline-title |title=DNA damage tolerance in hematopoietic stem and progenitor cells in mice. |date=15.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28761001 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565453 }} * {{medline-title |title=The effects of ingestion of hormonal host factors on the longevity and insecticide resistance phenotype of the major malaria vector Anopheles arabiensis (Diptera: Culicidae). |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28700639 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507448 }} * {{medline-title |title=Bioavailability of five hydrophobic organic compounds to earthworms from sterile and non-sterile artificial soils. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28371706 |full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.03.117 }} * {{medline-title |title=The effect of elevated temperatures on the life history and insecticide resistance phenotype of the major malaria vector Anopheles arabiensis (Diptera: Culicidae). |date=14.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28193292 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307775 }} * {{medline-title |title=Dichotic Digits Test Performance Across the Ages: Results From Two Large Epidemiologic Cohort Studies. |date=05-06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27941404 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404957 }} * {{medline-title |title=The Role of Oxidative Stress in the Longevity and Insecticide Resistance Phenotype of the Major Malaria Vectors Anopheles arabiensis and Anopheles funestus. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26964046 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786153 }} * {{medline-title |title=Nuclear hormone receptor DHR96 mediates the resistance to xenobiotics but not the increased lifespan of insulin-mutant Drosophila. |date=02.02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26787908 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747718 }} * {{medline-title |title=Influence of feeding and earthworm density on compound bioaccumulation in earthworms Eisenia andrei. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26378968 |full-text-url=https://sci-hub.do/10.1016/j.envpol.2015.09.025 }} * {{medline-title |title=Greater cognitive decline with aging among elders with high serum concentrations of organochlorine pesticides. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26107947 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480979 }} * {{medline-title |title=The effect of multiple blood-feeding on the longevity and insecticide resistant phenotype in the major malaria vector Anopheles arabiensis (Diptera: Culicidae). |date=23.08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25150975 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161849 }} * {{medline-title |title=The role of canine distemper virus and 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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30537739 |full-text-url=https://sci-hub.do/10.1159/000495895 }} * {{medline-title |title=Functional pathways regulated by microRNA networks in CD8 T-cell aging. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30488559 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351841 }} * {{medline-title |title=Introduction to FOXO Biology. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30414140 |full-text-url=https://sci-hub.do/10.1007/978-1-4939-8900-3_1 }} * {{medline-title |title=Antioxidant modifications induced by the new metformin derivative HL156A regulate metabolic reprogramming in SAMP1/kl (-/-) mice. |date=16.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30222592 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188477 }} * {{medline-title |title=Master athletes have higher miR-7, [[SIRT3]] and [[SOD2]] expression in skeletal muscle than age-matched sedentary controls. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30107294 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092475 }} * {{medline-title |title=[[FOXO1]] and [[ETV6]] genes may represent novel regulators of splicing factor expression in cellular senescence. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30088951 |full-text-url=https://sci-hub.do/10.1096/fj.201801154R }} * {{medline-title |title=Autophagy mediators ([[FOXO1]], [[SESN3]] and [[TSC2]]) in Lewy body disease and aging. |date=25.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966750 |full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.06.052 }} * {{medline-title |title=FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29963746 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156454 }} * {{medline-title |title=Senescence Alters PPARγ (Peroxisome Proliferator-Activated Receptor Gamma)-Dependent Fatty Acid Handling in Human Adipose Tissue Microvascular Endothelial Cells and Favors Inflammation. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29545239 |full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.310797 }} * {{medline-title |title=[[HGF]] and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the [[SIRT1]]/[[FOXO1]] Signaling Pathway. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29462806 |full-text-url=https://sci-hub.do/10.1159/000487559 }} * {{medline-title |title=Role of Forkhead Box O (FOXO) transcription factor in aging and diseases. |date=30.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29428128 |full-text-url=https://sci-hub.do/10.1016/j.gene.2018.01.051 }} * {{medline-title |title=FOXO in Neural Cells and Diseases of the Nervous System. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29433734 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Disrupts the Regulatory Loop Among [[SIRT1]], [[FOXO1]], and eNOS. |date=20.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27960536 |full-text-url=https://sci-hub.do/10.1089/ars.2016.6643 }} * {{medline-title |title=miR-96, miR-145 and miR-9 expression increases, and IGF-1R and [[FOXO1]] expression decreases in peripheral blood mononuclear cells of aging humans. |date=30.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27903254 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131432 }} * {{medline-title |title=Cone Viability Is Affected by Disruption of Melatonin Receptors Signaling. |date=01.01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26780313 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727519 }} * {{medline-title |title=Effect of Aging on Periodontal Inflammation, Microbial Colonization, and Disease Susceptibility. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26762510 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802783 }} * {{medline-title |title=Long live FOXO: unraveling the role of FOXO proteins in aging and longevity. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26643314 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783344 }} * {{medline-title |title=Abrogation of Age-Induced MicroRNA-195 Rejuvenates the Senescent Mesenchymal Stem Cells by Reactivating Telomerase. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26390028 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797648 }} * {{medline-title |title=Endogenous ROS levels are increased in replicative senescence in human bone marrow mesenchymal stromal cells. |date=15.05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25839657 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.03.136 }} ==HMGB1== * {{medline-title |title=Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction. |date=02.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31633821 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885734 }} * {{medline-title |title=Targeting [[HMGB1]] by ethyl pyruvate ameliorates systemic lupus erythematosus and reverses the senescent phenotype of bone marrow-mesenchymal stem cells. |date=14.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31303606 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660056 }} * {{medline-title |title=[[HMGB1]] and Caveolin-1 related to [[RPE]] cell senescence in age-related macular degeneration. |date=07.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31284269 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660032 }} * {{medline-title |title=Dual faced [[HMGB1]] plays multiple roles in cardiomyocyte senescence and cardiac inflammatory injury. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31129019 |full-text-url=https://sci-hub.do/10.1016/j.cytogfr.2019.05.009 }} * {{medline-title |title=Neuroprotective Effect of Dioscin on the Aging Brain. |date=30.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30935017 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479446 }} * {{medline-title |title=Modulation of soluble receptor for advanced glycation end-products (RAGE) isoforms and their ligands in healthy aging. |date=23.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30903794 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461165 }} * {{medline-title |title=Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis. |date=30.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30910981 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500153 }} * {{medline-title |title=Serum and nutrient deprivation increase autophagic flux in intervertebral disc annulus fibrosus cells: an in vitro experimental study. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30847707 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538458 }} * {{medline-title |title=Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence. |date=01.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30735837 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2019.02.005 }} * {{medline-title |title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357 |full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004 }} * {{medline-title |title=Repeated abortion in adulthood induces cognition impairment in aged mice. |date=30.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30061639 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065382 }} * {{medline-title |title=Loss of DNA polymerase β induces cellular senescence. |date=08.2018 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{{medline-title |title=Changes in pro-inflammatory markers and leucine concentrations in response to Nordic Walking training combined with vitamin D supplementation in elderly women. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28316011 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514208 }} * {{medline-title |title=Systemic [[HMGB1]] Neutralization Prevents Postoperative Neurocognitive Dysfunction in Aged Rats. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27822212 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075578 }} * {{medline-title |title=The Alarmin [[HMGB1]] Mediates Age-Induced Neuroinflammatory Priming. |date=27.07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27466339 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961779 }} * {{medline-title |title=Human fetal membranes at term: Dead tissue or signalers of parturition? |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27452431 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|title=Impaired proteostasis in senescent vascular endothelial cells: a perspective on estrogen and oxidative stress in the aging vasculature. |date=01.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30499713 |full-text-url=https://sci-hub.do/10.1152/ajpheart.00318.2018 }} * {{medline-title |title=Leukocyte Telomere Length in Patients with Radiographic Knee Osteoarthritis. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30488497 |full-text-url=https://sci-hub.do/10.1002/em.22247 }} * {{medline-title |title=Klotho at the Edge of Alzheimer's Disease and Senile Depression. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29978424 |full-text-url=https://sci-hub.do/10.1007/s12035-018-1200-z }} * {{medline-title |title=Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29890178 |full-text-url=https://sci-hub.do/10.1016/j.mad.2018.06.002 }} * {{medline-title |title=G-395A polymorphism in the promoter region of the [[KL]]OTHO gene associates with frailty among the oldest-old. |date=30.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29712948 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928057 }} * {{medline-title |title=Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of [[RIG]]-I/NF-κB Signaling. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29403373 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778393 }} * {{medline-title |title=Changes in expression of klotho affect physiological processes, diseases, and cancer. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433 }} * {{medline-title |title=Anti-aging factor, serum alpha-Klotho, as a marker of acute physiological stress, and a predictor of ICU mortality, in patients with septic shock. |date=04.2018 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Mothers with Gestational Diabetes Mellitus. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30645713 |full-text-url=https://sci-hub.do/10.1007/s12015-019-9872-y }} * {{medline-title |title=Cycling CD4 T cells in HIV-infected immune nonresponders have mitochondrial dysfunction. |date=01.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320604 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205369 }} * {{medline-title |title=Increased [[TFAM]] binding to mtDNA damage hot spots is associated with mtDNA loss in aged rat heart. |date=20.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29969715 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319621 }} * {{medline-title |title=Restoring mitochondrial DNA copy number preserves mitochondrial function and delays vascular aging in mice. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29745022 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052475 }} * {{medline-title |title=Sestrin2 prevents age-related intolerance to post myocardial infarction via AMPK/[[PGC]]-1α pathway. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325933 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820139 }} * {{medline-title |title=Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203401 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.022 }} * {{medline-title |title=Dietary supplementation with acetyl-l-carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807823 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.017 }} * {{medline-title |title=Effect of lifelong football training on the expression of muscle molecular markers involved in healthy longevity. 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live so long?" The mitochondrial contribution to longevity through balance of mitochondrial dynamics and mtDNA content. |date=01.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27620821 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922457 }} * {{medline-title |title=Response of [[BAX]], Bcl-2 Proteins, and [[SIRT1]]/[[PGC]]-1α mRNA Expression to 8-Week Treadmill Running in the Aging Rat Skeletal Muscle. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27526155 |full-text-url=https://sci-hub.do/10.1007/978-3-319-38810-6_38 }} * {{medline-title |title=Methylene blue improves sensorimotor phenotype and decreases anxiety in parallel with activating brain mitochondria biogenesis in mid-age mice. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27515402 |full-text-url=https://sci-hub.do/10.1016/j.neures.2016.07.006 }} * {{medline-title |title=HIF-1 regulates insect lifespan extension by inhibiting c-Myc-[[TFAM]] signaling and mitochondrial biogenesis. |date=11.2016 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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24410488 |full-text-url=https://sci-hub.do/10.1089/rej.2014.1546 }} ==ASL== * {{medline-title |title=Increased blood-brain barrier permeability to water in the aging brain detected using noninvasive multi-TE [[ASL]] MRI. |date=01.2021 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32910547 |full-text-url=https://sci-hub.do/10.1002/mrm.28496 }} * {{medline-title |title=Quantitative Cerebrovascular Reactivity in Normal Aging: Comparison Between Phase-Contrast and Arterial Spin Labeling MRI. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32849217 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411174 }} * {{medline-title |title=Correcting Task fMRI Signals for Variability in Baseline CBF Improves BOLD-Behavior Relationships: A Feasibility Study in an Aging Model. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32425745 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205008 }} * {{medline-title |title=Cerebral Blood Flow in Community-Based Older Twins Is Moderately Heritable: An Arterial Spin Labeling Perfusion Imaging Study. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31333444 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615405 }} * {{medline-title |title=A longitudinal characterization of perfusion in the aging brain and associations with cognition and neural structure. |date=15.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31062904 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693488 }} * {{medline-title |title=Cortical cerebral blood flow in ageing: effects of haematocrit, sex, ethnicity and diabetes. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30887200 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719435 }} * {{medline-title |title=Exercise-stimulated arterial transit time in calf muscles measured by dynamic contrast-enhanced magnetic resonance imaging. |date=01.2019 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|title=The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30235328 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147527 }} * {{medline-title |title=Cost effectiveness of population based [[BRCA1]] founder mutation testing in Sephardi Jewish women. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29288066 |full-text-url=https://sci-hub.do/10.1016/j.ajog.2017.12.221 }} * {{medline-title |title=Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions. |date=04.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29249653 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756112 }} * {{medline-title |title=Faulty [[BRCA1]], [[BRCA2]] genes: how poor is the prognosis? |date=10.2017 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}} * {{medline-title |title=[[BDNF]] and [[COMT]] polymorphisms have a limited association with episodic memory performance or engagement in complex cognitive activity in healthy older adults. |date=04.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24468545 |full-text-url=https://sci-hub.do/10.1016/j.nlm.2014.01.013 }} ==LRRK2== * {{medline-title |title=Accelerated telomere shortening independent of [[LRRK2]] variants in Chinese patients with Parkinson's disease. |date=29.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33122450 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655166 }} * {{medline-title |title=The effect of [[LRRK2]] loss-of-function variants in humans. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32461697 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303015 }} * {{medline-title |title=Parkinson's disease-related Leucine-rich repeat kinase 2 modulates nuclear morphology and genomic stability in striatal projection neurons 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|title=SENEBLOC, a long non-coding RNA suppresses senescence via p53-dependent and independent mechanisms. |date=06.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32030426 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102969 }} * {{medline-title |title=Disruption of Robo2-Baiap2 integrated signaling drives cystic disease. |date=19.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31534052 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795383 }} * {{medline-title |title=Senescence-induced immunophenotype, gene expression and electrophysiology changes in human amniocytes. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31478614 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815807 }} * {{medline-title |title=Hsp90β interacts with [[MDM2]] to suppress p53-dependent senescence during skeletal muscle regeneration. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31313490 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718578 }} * {{medline-title |title=TZAP plays an inhibitory role in the self-renewal of porcine mesenchymal stromal cells and is implicated the regulation of premature senescence via the p53 pathway. |date=07.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30845965 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404308 }} * {{medline-title |title=Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells. |date=28.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30647108 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367206 }} * {{medline-title |title=The SCF ubiquitin ligase complex mediates degradation of the tumor suppressor [[FBXO31]] and thereby prevents premature cellular senescence. |date=19.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171069 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200945 }} * {{medline-title |title=The Dysfunctional [[MDM2]]-p53 Axis in Adipocytes Contributes to Aging-Related Metabolic Complications by Induction of Lipodystrophy. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131393 |full-text-url=https://sci-hub.do/10.2337/db18-0684 }} * {{medline-title |title=Effect of [[CCNB1]] silencing on cell cycle, senescence, and apoptosis through the p53 signaling pathway in pancreatic cancer. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30069972 |full-text-url=https://sci-hub.do/10.1002/jcp.26816 }} * {{medline-title |title=Boosting [[ATM]] activity alleviates aging and extends lifespan in a mouse model of progeria. |date=02.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29717979 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957528 }} * {{medline-title |title=Acute [[HSF1]] depletion induces cellular senescence through the [[MDM2]]-p53-p21 pathway in human diploid fibroblasts. |date=08.05.2018 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pathway affect longevity in a gender specific manner. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24654968 |full-text-url=https://sci-hub.do/10.2174/1874609807666140321150751 }} ==SIRT2== * {{medline-title |title=Melatonin ameliorates the advanced maternal age-associated meiotic defects in oocytes through the [[SIRT2]]-dependent H4K16 deacetylation pathway. |date=24.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31980591 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053624 }} * {{medline-title |title=[[SIRT2]] functions in aging, autophagy, and apoptosis in post-maturation bovine oocytes. |date=01.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31295472 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116639 }} * {{medline-title |title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296 }} * {{medline-title |title=Mitochondrial Stress-Initiated Aberrant Activation of the [[NLRP3]] Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging. |date=22.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30673616 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371804 }} * {{medline-title |title=Hsp90 Stabilizes [[SIRT1]] Orthologs in Mammalian Cells and [i]C. elegans[/i]. |date=20.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463299 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274930 }} * {{medline-title |title=Tenovin-1 Induces Senescence and Decreases Wound-Healing Activity in Cultured Rat Primary Astrocytes. |date=01.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30092626 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513186 }} * {{medline-title |title=High expression of CPT1b in skeletal muscle in metabolically healthy older subjects. |date=04.2019 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related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25834936 |full-text-url=https://sci-hub.do/10.1016/j.patbio.2015.03.002 }} * {{medline-title |title=Prophylactic lithium alleviates splenectomy-induced cognitive dysfunction possibly by inhibiting hippocampal [[TLR4]] activation in aged rats. |date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25839444 |full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2015.02.008 }} * {{medline-title |title=Altered neutrophil functions in elderly patients during a 6-month follow-up period after a hip fracture. |date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25797136 |full-text-url=https://sci-hub.do/10.1016/j.exger.2015.03.009 }} * {{medline-title |title=Aging does not affect the ability of human monocyte-derived dendritic cells to phagocytose Candida albicans. |date=12.2015 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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33080556 |full-text-url=https://sci-hub.do/10.1016/j.jhazmat.2020.124159 }} * {{medline-title |title=Nanoscale infrared, thermal and mechanical properties of aged microplastics revealed by an atomic force microscopy coupled with infrared spectroscopy ([[AFM]]-IR) technique. |date=20.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32702545 |full-text-url=https://sci-hub.do/10.1016/j.scitotenv.2020.140944 }} * {{medline-title |title=Detecting zeta potential of polydimethylsiloxane (PDMS) in electrolyte solutions with atomic force microscope. |date=15.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32521351 |full-text-url=https://sci-hub.do/10.1016/j.jcis.2020.05.061 }} * {{medline-title |title=Recent Applications of Advanced Atomic Force Microscopy in Polymer Science: A Review. |date=17.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32429499 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284686 }} * {{medline-title |title=Active fractions of mannoproteins derived from yeast cell wall stimulate innate and acquired immunity of adult and elderly dogs. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32288071 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126846 }} * {{medline-title |title=The Effect of Waste Engine Oil and Waste Polyethylene on UV Aging Resistance of Asphalt. |date=06.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32155867 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182932 }} * {{medline-title |title=Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans. |date=25.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32098962 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042263 }} * {{medline-title |title=Nanomechanical insights: Amyloid beta oligomer-induced senescent brain endothelial cells. |date=01.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31513781 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791778 }} * {{medline-title |title=Application of atomic force microscopy in the analysis of time since deposition (TSD) of red blood cells in bloodstains: A forensic analysis. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31181409 |full-text-url=https://sci-hub.do/10.1016/j.forsciint.2019.05.048 }} * {{medline-title |title=Iceland spar calcite: Humidity and time effects on surface properties and their reversibility. |date=01.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30682592 |full-text-url=https://sci-hub.do/10.1016/j.jcis.2019.01.047 }} * {{medline-title |title=Zebrafish as a model to study bone maturation: Nanoscale structural and mechanical characterization of age-related changes in the zebrafish vertebral column. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29747057 |full-text-url=https://sci-hub.do/10.1016/j.jmbbm.2018.05.004 }} * {{medline-title |title=Multiscale Poroviscoelastic Compressive Properties of Mouse Supraspinatus Tendons Are Altered in Young and Aged Mice. |date=01.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29238818 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816244 }} * {{medline-title |title=Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28812215 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665708 }} * {{medline-title |title=Effect of intra-oral aging on t→m phase transformation, microstructure, and mechanical properties of Y-TZP dental ceramics. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28432999 |full-text-url=https://sci-hub.do/10.1016/j.jmbbm.2017.04.014 }} * {{medline-title |title=The Effect of Brushing and Aging on the Staining and Smoothness of Resin Composites. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28194869 |full-text-url=https://sci-hub.do/10.1111/jerd.12293 }} * {{medline-title |title=Frequency-modulated atomic force microscopy localises viscoelastic remodelling in the ageing sheep aorta. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27479890 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020410 }} * {{medline-title |title=Changes in surface characteristics of two different resin composites after 1 year water storage: An SEM and [[AFM]] study. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27062131 |full-text-url=https://sci-hub.do/10.1002/sca.21317 }} * {{medline-title |title=Wide bandwidth nanomechanical assessment of murine cartilage reveals protection of aggrecan knock-in mice from joint-overuse. |date=14.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27086115 |full-text-url=https://sci-hub.do/10.1016/j.jbiomech.2016.03.055 }} * {{medline-title |title=Effect of at-home bleaching with different thickeners and aging on physical properties of a nanocomposite. |date=01-03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27011745 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784160 }} * {{medline-title |title=Interaction of intraocular lenses with fibronectin and human lens epithelial cells: Effect of chemical composition and aging. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26112694 |full-text-url=https://sci-hub.do/10.1002/jbm.a.35528 }} * {{medline-title |title=β-Hydroxy-β-methylbutyrate (HMB) supplementation and resistance exercise significantly reduce abdominal adiposity in healthy elderly men. |date=04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25700845 |full-text-url=https://sci-hub.do/10.1016/j.exger.2015.02.012 }} * {{medline-title |title=Atomic force microscopy reveals age-dependent changes in nanomechanical properties of the extracellular matrix of native human menisci: implications for joint degeneration and osteoarthritis. |date=11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24972006 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374607 }} * {{medline-title |title=In situ atomic force microscopy analysis of morphology and particle size changes in lithium iron phosphate cathode during discharge. |date=01.06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24703680 |full-text-url=https://sci-hub.do/10.1016/j.jcis.2014.02.035 }} * {{medline-title |title=Load cycling enhances bioactivity at the resin-dentin interface. |date=07.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24630703 |full-text-url=https://sci-hub.do/10.1016/j.dental.2014.02.009 }} ==GSC== * {{medline-title |title=[i]mastermind[/i] regulates niche ageing independently of the [i]Notch[/i] pathway in the [i]Drosophila[/i] ovary. |date=29.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31744422 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893403 }} * {{medline-title |title=Germline stem cell homeostasis. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31155359 |full-text-url=https://sci-hub.do/10.1016/bs.ctdb.2019.04.006 }} * {{medline-title |title=Endocrine regulation of female germline stem cells in the fruit fly Drosophila melanogaster. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31109668 |full-text-url=https://sci-hub.do/10.1016/j.cois.2018.07.001 }} * {{medline-title |title=Generation of Inducible Gene-Switched GAL4 Expressed in the [i]Drosophila[/i] Female Germline Stem Cell Niche. |date=05.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31018943 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553524 }} * {{medline-title |title=YAP/Yorkie in the germline modulates the age-related decline of germline stem cells and niche cells. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30943201 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447158 }} * {{medline-title |title=Diminished Jak/STAT Signaling Causes Early-Onset Aging Defects in Stem Cell Cytokinesis. |date=21.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30612906 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783278 }} * {{medline-title |title=JNK signaling triggers spermatogonial dedifferentiation during chronic stress to maintain the germline stem cell pool in the [i]Drosophila[/i] testis. |date=09.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29985130 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070334 }} * {{medline-title |title=Age-related differences in BOLD modulation to cognitive control costs in a multitasking paradigm: Global switch, local switch, and compatibility-switch costs. |date=15.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29414492 |full-text-url=https://sci-hub.do/10.1016/j.neuroimage.2018.01.030 }} * {{medline-title |title=Modelling glioblastoma tumour-host cell interactions using adult brain organotypic slice co-culture. |date=22.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196443 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894940 }} * {{medline-title |title=Loss of [i]foxo[/i] rescues stem cell aging in [i]Drosophila[/i] germ line. |date=19.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28925355 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644957 }} * {{medline-title |title=DAF-18/PTEN signals through AAK-1/AMPK to inhibit MPK-1/MAPK in feedback control of germline stem cell proliferation. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28410423 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409174 }} * {{medline-title |title=Antithrombotic agents intake prior to injury does not affect outcome after a traumatic brain injury in hospitalized elderly patients. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28110930 |full-text-url=https://sci-hub.do/10.1016/j.jocn.2016.12.032 }} * {{medline-title |title=Suberoylanilide hydroxamic acid represses glioma stem-like cells. |date=18.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27863490 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116136 }} * {{medline-title |title=Flavonoids and darkness lower PCD in senescing Vitis vinifera suspension cell cultures. |date=26.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27782806 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080730 }} * {{medline-title |title=DNA damage-induced Lok/CHK2 activation compromises germline stem cell self-renewal and lineage differentiation. |date=01.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27729408 |full-text-url=https://sci-hub.do/10.1242/dev.141069 }} * {{medline-title |title=The Wnt pathway limits BMP signaling outside of the germline stem cell niche in Drosophila ovaries. |date=01.09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27364467 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001506 }} * {{medline-title |title=Nuclear hormone receptors as mediators of metabolic adaptability following reproductive perturbations. |date=01-03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27073739 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805359 }} * {{medline-title |title=Senescence from glioma stem cell differentiation promotes tumor growth. |date=05.02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26775840 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176357 }} * {{medline-title |title=Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence. |date=24.08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26196144 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541496 }} * {{medline-title |title=Microglial voltage-gated sodium channels modulate cellular response in Alzheimer's disease--a new perspective on an old problem. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25826483 }} * {{medline-title |title=Y-27632, a ROCK inhibitor, delays senescence of putative murine salivary gland stem cells in culture. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25804560 |full-text-url=https://sci-hub.do/10.1016/j.archoralbio.2015.03.003 }} * {{medline-title |title=Notch signaling mediates the age-associated decrease in adhesion of germline stem cells to the niche. |date=12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25521289 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270478 }} * {{medline-title |title=Aging and insulin signaling differentially control normal and tumorous germline stem cells. |date=02.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25470527 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326914 }} * {{medline-title |title=[The opportunity to use combined stem cells transplantation for haemopoesis activation in the old and mature laboratory animals under the conditions of ionizing radiation]. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25306670 }} ==HGF== * {{medline-title |title=Age-related changes in the immunomodulatory effects of human dental pulp derived mesenchymal stem cells on the CD4 T cell subsets. |date=19.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33223447 |full-text-url=https://sci-hub.do/10.1016/j.cyto.2020.155367 }} * {{medline-title |title=Hepatocyte growth factor ([[HGF]]) and stem cell factor (SCF) maintained the stemness of human bone marrow mesenchymal stem cells (hBMSCs) during long-term expansion by preserving mitochondrial function via the PI3K/AKT, ERK1/2, and STAT3 signaling pathways. |date=31.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32736659 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393921 }} * {{medline-title |title=Phenytoin sodium-ameliorated gingival fibroblast aging is associated with autophagy. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32281104 |full-text-url=https://sci-hub.do/10.1111/jre.12750 }} * {{medline-title |title=Impaired integrin α /β -mediated hepatocyte growth factor release by stellate cells of the aged liver. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32157808 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189994 }} * {{medline-title |title=Evaluation of the biological behaviour of various dental implant abutment materials on attachment and viability of human gingival fibroblasts. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31060818 |full-text-url=https://sci-hub.do/10.1016/j.dental.2019.04.010 }} * {{medline-title |title=Characterization of aged rat vocal fold fibroblasts. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30450675 |full-text-url=https://sci-hub.do/10.1002/lary.27464 }} * {{medline-title |title=Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30354979 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101979 }} * {{medline-title |title=Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging. |date=26.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30373163 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274848 }} * {{medline-title |title=Hepatocyte growth factor is a potential biomarker for osteoproliferation and osteoporosis in ankylosing spondylitis. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30306221 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449322 }} * {{medline-title |title=Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factor. |date=09.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29523193 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845161 }} * {{medline-title |title=[[HGF]] and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the [[SIRT1]]/[[FOXO1]] Signaling Pathway. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29462806 |full-text-url=https://sci-hub.do/10.1159/000487559 }} * {{medline-title |title=Cell-size-dependent upregulation of [[HGF]] expression in dermal fibroblasts: Impact on human skin connective tissue aging. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28826691 |full-text-url=https://sci-hub.do/10.1016/j.jdermsci.2017.08.003 }} * {{medline-title |title=Oxidative stress contributes to hepatocyte growth factor-dependent pro-senescence activity of ovarian cancer cells. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28652056 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2017.06.015 }} * {{medline-title |title=Estrogen modulates mesenchyme-epidermis interactions in the adult nipple. |date=15.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28289136 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399661 }} * {{medline-title |title=Enhanced Functional Recovery from Spinal Cord Injury in Aged Mice after Stem Cell Transplantation through [[HGF]] Induction. |date=14.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28216143 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355635 }} * {{medline-title |title=Necroptosis Induced by Ad-[[HGF]] Activates Endogenous C-Kit Cardiac Stem Cells and Promotes Cardiomyocyte Proliferation and Angiogenesis in the Infarcted Aged Heart. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27941320 |full-text-url=https://sci-hub.do/10.1159/000453144 }} * {{medline-title |title=Ovarian cancer-derived ascitic fluids induce a senescence-dependent pro-cancerogenic phenotype in normal peritoneal mesothelial cells. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27444787 |full-text-url=https://sci-hub.do/10.1007/s13402-016-0289-1 }} * {{medline-title |title=Influence of aging on the quantity and quality of human cardiac stem cells. |date=07.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26947751 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780032 }} * {{medline-title |title=Senescent peritoneal mesothelium induces a pro-angiogenic phenotype in ovarian cancer cells in vitro and in a mouse xenograft model in vivo. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26433963 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740564 }} * {{medline-title |title=Macrophage migration inhibitory factor confers resistance to senescence through [[CD74]]-dependent AMPK-FOXO3a signaling in mesenchymal stem cells. |date=22.04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25896286 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453287 }} * {{medline-title |title=Prevention of hair graying by factors that promote the growth and differentiation of melanocytes. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25099157 |full-text-url=https://sci-hub.do/10.1111/1346-8138.12570 }} * {{medline-title |title=Low-power laser irradiation fails to improve liver regeneration in elderly rats at 48 h after 70 % resection. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24880927 |full-text-url=https://sci-hub.do/10.1007/s10103-014-1598-0 }} * {{medline-title |title=Effect of AST on age-associated changes of vocal folds in a rat model. |date=10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24764173 |full-text-url=https://sci-hub.do/10.1002/lary.24733 }} * {{medline-title |title=The role of growth factors in maintenance of stemness in bone marrow-derived mesenchymal stem cells. |date=28.02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24491556 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2014.01.084 }} ==SOX2== * {{medline-title |title=Multiple nanosecond pulsed electric fields stimulation with conductive poly(l-lactic acid)/carbon nanotubes films maintains the multipotency of mesenchymal stem cells during prolonged in vitro culture. |date=08.2020 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|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116562 }} * {{medline-title |title=Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis. |date=30.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30910981 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500153 }} * {{medline-title |title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014 }} * {{medline-title |title=Isolation, Characterization, and Differentiation of Cardiac Stem Cells from the Adult Mouse Heart. |date=07.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30663680 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207148 }} * {{medline-title |title=A stably self-renewing adult blood-derived 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|title=Expression of apoptosis-related genes in liver-specific growth hormone receptor gene-disrupted mice is sex dependent. |date=01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24550353 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296163 }} ==VDR== * {{medline-title |title=25-Hydroxyvitamin D positively regulates periodontal inflammaging via SOCS3/STAT signaling in diabetic mice. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31917967 |full-text-url=https://sci-hub.do/10.1016/j.steroids.2019.108570 }} * {{medline-title |title=1,25-Dihydroxyvitamin D protects against age-related osteoporosis by a novel [[VDR]]-Ezh2-p16 signal axis. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31880094 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996957 }} * {{medline-title |title=Active vitamin D impedes the progression of non-alcoholic fatty liver disease by inhibiting cell senescence in a rat model. |date=09.2020 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{{medline-title |title=[[VDR]] Activation Reduces Proteinuria and High-Glucose-Induced Injury of Kidneys and Podocytes by Regulating Wnt Signaling Pathway. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28848172 |full-text-url=https://sci-hub.do/10.1159/000480315 }} * {{medline-title |title=Vitamin D and the brain: Genomic and non-genomic actions. |date=15.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28579120 |full-text-url=https://sci-hub.do/10.1016/j.mce.2017.05.035 }} * {{medline-title |title=Targeted next generation sequencing of the entire vitamin D receptor gene reveals polymorphisms correlated with vitamin D deficiency among older Filipino women with and without fragility fracture. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28068558 |full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2016.12.003 }} * {{medline-title |title=Using Hyperpolarized Xe MRI to Quantify the Pulmonary Ventilation Distribution. |date=12.2016 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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25595352 |full-text-url=https://sci-hub.do/10.1016/j.gene.2015.01.022 }} * {{medline-title |title=Effect modification by vitamin D receptor genetic polymorphisms in the association between cumulative lead exposure and pulse pressure: a longitudinal study. |date=13.01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25582168 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417283 }} * {{medline-title |title=Vitamin D receptor and megalin gene polymorphisms are associated with central adiposity status and changes among US adults. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25191583 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153078 }} * {{medline-title |title=Vitamin D signaling in myogenesis: potential for treatment of sarcopenia. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25197630 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147791 }} ==EZH2== * {{medline-title |title=Linking gene expression and phenotypic changes in the developmental and evolutionary origins of osteosclerosis in the ribs of bowhead whales (Balaena mysticetus). |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32729176 |full-text-url=https://sci-hub.do/10.1002/jez.b.22990 }} * {{medline-title |title=[[EZH2]] is involved in vulnerability to neuroinflammation and depression-like behaviors induced by chronic stress in different aged mice. |date=01.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32553389 |full-text-url=https://sci-hub.do/10.1016/j.jad.2020.03.154 }} * {{medline-title |title=A positive feedback loop between [[EZH2]] and NOX4 regulates nucleus pulposus cell senescence in age-related intervertebral disc degeneration. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32025238 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995653 }} * {{medline-title |title=Perinatal exposure to bisphenol A impacts in the mammary gland morphology of adult Mongolian gerbils. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31917966 |full-text-url=https://sci-hub.do/10.1016/j.yexmp.2020.104374 }} * {{medline-title |title=Long noncoding RNA MALAT1 potentiates growth and inhibits senescence by antagonizing [[ABI3BP]] in gallbladder cancer cells. |date=07.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174563 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555920 }} * {{medline-title |title=Epigenetic Co-Deregulation of [[EZH2]]/[[TET1]] is a Senescence-Countering, Actionable Vulnerability in Triple-Negative Breast Cancer. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30809307 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376470 }} * {{medline-title |title=Improving Treatment for Myelodysplastic Syndromes Patients. |date=25.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30362079 |full-text-url=https://sci-hub.do/10.1007/s11864-018-0583-4 }} * {{medline-title |title=Aging Suppresses Skin-Derived Circulating SDF1 to Promote Full-Thickness Tissue Regeneration. |date=25.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30257200 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261459 }} * {{medline-title |title=Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells. |date=05.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30194939 |full-text-url=https://sci-hub.do/10.1016/j.ejphar.2018.09.005 }} * {{medline-title |title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456 |full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341 }} * {{medline-title |title=Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage- and Histone Methylation-Dependent Pathways. |date=27.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29590617 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9c Regulate Age-Dependent Mesenchymal Stem Cell Differentiation into Osteoblasts and Adipocytes. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27250566 |full-text-url=https://sci-hub.do/10.1002/stem.2400 }} * {{medline-title |title=Insight into the molecular pathophysiology of myelodysplastic syndromes: targets for novel therapy. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27147278 |full-text-url=https://sci-hub.do/10.1111/ejh.12771 }} * {{medline-title |title=[[HBP1]]-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/[[EZH2]] Pathways and Its Impact on Cell Senescence and Tumorigenesis. |date=10.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27129219 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933444 }} * {{medline-title |title=New concept: cellular senescence in pathophysiology of cholangiocarcinoma. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26680649 |full-text-url=https://sci-hub.do/10.1586/17474124.2016.1133291 }} * {{medline-title |title=[[SIRT1]] affects DNA methylation of polycomb group protein target genes, a hotspot of the epigenetic shift observed in ageing. |date=24.06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26104761 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480908 }} * {{medline-title |title=Enhancer of zeste homolog 2 depletion induces cellular senescence via histone demethylation along the INK4/ARF locus. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26004298 |full-text-url=https://sci-hub.do/10.1016/j.biocel.2015.05.011 }} * {{medline-title |title=Polycomb repressive complex 2 epigenomic signature defines age-associated hypermethylation and gene expression changes. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25880792 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623031 }} * {{medline-title |title=Luotonin-A based quinazolinones cause apoptosis and senescence via HDAC inhibition and activation of tumor suppressor proteins in HeLa cells. |date=13.04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25757092 |full-text-url=https://sci-hub.do/10.1016/j.ejmech.2015.02.057 }} ==MAPT== * {{medline-title |title=Association of relative brain age with tobacco smoking, alcohol consumption, and genetic variants. |date=30.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32001736 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992742 }} * {{medline-title |title=A blood-based nutritional risk index explains cognitive enhancement and decline in the multidomain Alzheimer prevention trial. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31921969 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944714 }} * {{medline-title |title=Longitudinal associations of physical activity levels with morphological and functional changes related with aging: The [[MAPT]] study. |date=12.2019 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|title=Mitophagy and NAD inhibit Alzheimer disease. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30922179 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526831 }} * {{medline-title |title=Cognitive changes of older adults with an equivocal amyloid load. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30689016 |full-text-url=https://sci-hub.do/10.1007/s00415-019-09203-5 }} * {{medline-title |title=Tauopathy: A common mechanism for neurodegeneration and brain aging. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30668956 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377302 }} * {{medline-title |title=Cinnamaldehyde Improves Lifespan and Healthspan in [i]Drosophila melanogaster[/i] Models for Alzheimer's Disease. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228985 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136480 }} * {{medline-title |title=Sex and age interact to determine clinicopathologic 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{{medline-title |title=Evaluating the Patterns of Aging-Related Tau Astrogliopathy Unravels Novel Insights Into Brain Aging and Neurodegenerative Diseases. |date=01.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28340083 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251691 }} * {{medline-title |title=CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of [[GRN]]/P[[GRN]]. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28189700 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389672 }} * {{medline-title |title=Koolen-de Vries Syndrome: Clinical Report of an Adult and Literature Review. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27852077 |full-text-url=https://sci-hub.do/10.1159/000452724 }} * {{medline-title |title=Presymptomatic cognitive decline in familial frontotemporal dementia: A longitudinal study. |date=26.07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27358337 |full-text-url=https://sci-hub.do/10.1212/WNL.0000000000002895 }} * {{medline-title |title=Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis. |date=24.02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912063 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765225 }} * {{medline-title |title=Cellular and molecular modifier pathways in tauopathies: the big picture from screening invertebrate models. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26756400 |full-text-url=https://sci-hub.do/10.1111/jnc.13532 }} * {{medline-title |title=Drosophila models of Alzheimer's disease: advances, limits, and perspectives. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25697708 |full-text-url=https://sci-hub.do/10.3233/JAD-142802 }} * {{medline-title |title=Association between [[MAPT]] haplotype and memory function in patients with Parkinson's disease and healthy aging individuals. |date=03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25577413 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353560 }} ==MBP== * {{medline-title |title=Demyelination associated with chronic arsenic exposure in Wistar rats. |date=15.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32171569 |full-text-url=https://sci-hub.do/10.1016/j.taap.2020.114955 }} * {{medline-title |title=Natural killer cells as participants in pathogenesis of rat experimental autoimmune encephalomyelitis (EAE): lessons from research on rats with distinct age and strain. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32140045 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050050 }} * {{medline-title |title=Whey protein concentrate supplementation protects rat brain against aging-induced oxidative stress and neurodegeneration. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29199432 |full-text-url=https://sci-hub.do/10.1139/apnm-2017-0578 }} * {{medline-title |title=Strain specificities in age-related changes in mechanisms promoting and controlling rat spinal cord damage in experimental autoimmune encephalomyelitis. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29128575 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.002 }} * {{medline-title |title=Age-dependent differences in myelin basic protein expression in the hippocampus of young, adult and aged gerbils. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29046699 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645602 }} * {{medline-title |title=Schwann Cell Phenotype Changes in Aging Human Dental Pulp. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28972819 |full-text-url=https://sci-hub.do/10.1177/0022034517733967 }} * {{medline-title |title=Blood pressure reactivity to mental stress is attenuated following resistance exercise in older hypertensive women. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28553088 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439937 }} * {{medline-title |title=Higher levels of myelin phospholipids in brains of neuronal α-Synuclein transgenic mice precede myelin loss. |date=08.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28482862 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421332 }} * {{medline-title |title=Traffic-related air pollution impact on mouse brain accelerates myelin and neuritic aging changes with specificity for [[CA1]] neurons. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28212893 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388507 }} * {{medline-title |title=Postnatal alteration of monocarboxylate transporter 1 expression in the rat corpus callosum. |date=04.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27982679 |full-text-url=https://sci-hub.do/10.33549/physiolres.933365 }} * {{medline-title |title=Bowel Preparation Is Associated with Reduced Morbidity in Elderly Patients Undergoing Elective Colectomy. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27896654 |full-text-url=https://sci-hub.do/10.1007/s11605-016-3314-9 }} * {{medline-title |title=Myelin Basic Protein Regulates Primitive and Definitive Neural Stem Cell Proliferation from the Adult Spinal Cord. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27573615 |full-text-url=https://sci-hub.do/10.1002/stem.2488 }} * {{medline-title |title=Isoaspartic acid is present at specific sites in myelin basic protein from multiple sclerosis patients: could this represent a trigger for disease onset? |date=12.08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27519525 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983062 }} * {{medline-title |title=Generation of a LacZ reporter transgenic mouse line for the stereological analysis of oligodendrocyte loss in galactosylceramidase deficiency. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27426866 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|title=Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence. |date=01.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30735837 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2019.02.005 }} * {{medline-title |title=Further Characterization of the Predominant Inner Retinal Degeneration of Aging Cln3 Knock-In Mice. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29721970 |full-text-url=https://sci-hub.do/10.1007/978-3-319-75402-4_50 }} * {{medline-title |title=Two novel forms of [[ERG]] oscillation in Drosophila: age and activity dependence. |date=03-06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29688104 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233714 }} * {{medline-title |title=Loss of [[XBP1]] accelerates age-related decline in retinal function and neurodegeneration. |date=04.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615095 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|title=p16 enhances the transcriptional and the apoptotic functions of p53 through DNA-dependent interaction. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28218424 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266037 }} * {{medline-title |title=Establishment and application of a novel patient-derived KIAA1549:[[BRAF]]-driven pediatric pilocytic astrocytoma model for preclinical drug testing. |date=14.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28002790 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355278 }} * {{medline-title |title=Phosphorylation of [[MITF]] by AKT affects its downstream targets and causes [[TP53]]-dependent cell senescence. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27702651 |full-text-url=https://sci-hub.do/10.1016/j.biocel.2016.09.029 }} * {{medline-title |title=Induction of DNA double-strand breaks and cellular senescence by human respiratory syncytial virus. |date=18.05.2016 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human dermal fibroblasts by down-regulating [[DNMT1]] via [[ZEB1]]. |date=16.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29466247 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842848 }} * {{medline-title |title=Microrna-217 modulates human skin fibroblast senescence by directly targeting DNA methyltransferase 1. |date=16.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28380423 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464883 }} * {{medline-title |title=A positive feedback loop between Pim-1 kinase and [[HBP1]] transcription factor contributes to hydrogen peroxide-induced premature senescence and apoptosis. |date=19.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28348080 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437229 }} * {{medline-title |title=miR-377 induces senescence in human skin fibroblasts by targeting DNA methyltransferase 1. |date=09.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28277545 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}} * {{medline-title |title=Erythropoietin Attenuates the Memory Deficits in Aging Rats by Rescuing the Oxidative Stress and Inflammation and Promoting [[BDNF]] Releasing. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26482461 |full-text-url=https://sci-hub.do/10.1007/s12035-015-9438-1 }} * {{medline-title |title=rh[[EPO]] affects apoptosis in hippocampus of aging rats by upregulating [[SIRT1]]. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26261574 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525908 }} * {{medline-title |title=Coated dextrin microcapsules of amlodipine incorporable into orally disintegrating tablets for geriatric patients. |date=10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25458788 |full-text-url=https://sci-hub.do/10.1016/j.biopha.2014.10.010 }} * {{medline-title |title=Neocytolysis: none, one or many? A reappraisal and future perspectives. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24592241 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924315 }} ==GAL== * {{medline-title |title=Overexpression of Pitx1 attenuates the senescence of chondrocytes from osteoarthritis degeneration cartilage-A self-controlled model for studying the etiology and treatment of osteoarthritis. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31783149 |full-text-url=https://sci-hub.do/10.1016/j.bone.2019.115177 }} * {{medline-title |title=β-Caryophyllene Reduces DNA Oxidation and the Overexpression of Glial Fibrillary Acidic Protein in the Prefrontal Cortex and Hippocampus of d-Galactose-Induced Aged BALB/c Mice. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31663807 |full-text-url=https://sci-hub.do/10.1089/jmf.2019.0111 }} * {{medline-title |title=Senescence-associated β-galactosidase activity in the developing avian retina. |date=09.2019 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|title=Manipulation of molecular pathways and senescence hallmarks by natural compounds in fibroblast cells. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30474871 |full-text-url=https://sci-hub.do/10.1002/jcb.27909 }} * {{medline-title |title=Ellagic acid reveals promising anti-aging effects against d-galactose-induced aging on human neuroblastoma cell line, SH-SY5Y: A mechanistic study. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30372874 |full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.10.024 }} * {{medline-title |title=Molecular and biochemical evidence on the protective role of ellagic acid and silybin against oxidative stress-induced cellular aging. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28887692 |full-text-url=https://sci-hub.do/10.1007/s11010-017-3172-0 }} * {{medline-title |title=Hyperphosphatemia induces senescence in human endothelial cells by increasing endothelin-1 production. |date=12.2017 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ontogeny and population variability of human hepatic dihydronicotinamide riboside:quinone oxidoreductase ([[NQO2]]). |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28346733 |full-text-url=https://sci-hub.do/10.1002/jbt.21921 }} * {{medline-title |title=Gardenia jasminoides extract-capped gold nanoparticles reverse hydrogen peroxide-induced premature senescence. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27693841 |full-text-url=https://sci-hub.do/10.1016/j.jphotobiol.2016.09.033 }} * {{medline-title |title=Stimulation of cellular senescent processes, including secretory phenotypes and anti-oxidant responses, after androgen deprivation therapy in human prostate cancer. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27329245 |full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2016.06.007 }} * {{medline-title |title=Exercise-induced Nrf2-signaling is impaired in aging. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27109910 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cognitive decline in elderly male mice. |date=15.01.2021 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32991925 |full-text-url=https://sci-hub.do/10.1016/j.bbr.2020.112939 }} * {{medline-title |title=Immune Signaling in Neurodegeneration. |date=16.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30995509 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822103 }} * {{medline-title |title=The Triggering Receptor Expressed on Myeloid Cells-2 (TREM-2) as Expression of the Relationship between Microglia and Alzheimer's Disease: A Novel Marker for a Promising Pathway to Explore. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30997915 |full-text-url=https://sci-hub.do/10.14283/jfa.2018.43 }} * {{medline-title |title=[[TREM2]] triggers microglial density and age-related neuronal loss. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30548312 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590266 }} * {{medline-title |title=Differential effects of partial and complete loss of [[TREM2]] on microglial injury response and tauopathy. |date=02.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30232263 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176614 }} * {{medline-title |title=Whole-Exome Sequencing of an Exceptional Longevity Cohort. |date=16.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723 }} * {{medline-title |title=Differential Phagocytic Properties of CD45 Microglia and CD45 Brain Mononuclear Phagocytes-Activation and Age-Related Effects. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29552013 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840283 }} * {{medline-title |title=Microglia and Aging: The Role of the [[TREM2]]-DAP12 and [[CX3CL1]]-[[CX3CR1]] Axes. |date=22.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29361745 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796261 }} * {{medline-title |title=A Tale of Two Genes: Microglial Apoe and Trem2. |date=19.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28930654 |full-text-url=https://sci-hub.do/10.1016/j.immuni.2017.08.015 }} * {{medline-title |title=[[TREM2]], Microglia, and Neurodegenerative Diseases. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28442216 |full-text-url=https://sci-hub.do/10.1016/j.molmed.2017.03.008 }} * {{medline-title |title=Neuroprotective Effect of TREM-2 in Aging and Alzheimer's Disease Model. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27662313 |full-text-url=https://sci-hub.do/10.3233/JAD-160663 }} * {{medline-title |title=Cerebrospinal fluid soluble [[TREM2]] in aging and Alzheimer's disease. |date=27.04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27121148 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848774 }} * {{medline-title |title=Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse 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Neuro-inflammatory Response to a Peripheral Acute LPS Challenge. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31749696 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848890 }} * {{medline-title |title=Upregulation of cannabinoid receptor type 2, but not [[TSPO]], in senescence-accelerated neuroinflammation in mice: a positron emission tomography study. |date=10.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31707986 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842455 }} * {{medline-title |title=Effects of age, BMI and sex on the glial cell marker [[[[TSPO]]]] - a multicentre [ C]PBR28 HRRT PET study. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31363804 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717599 }} * {{medline-title |title=Concentration, distribution, and influence of aging on the 18 kDa translocator protein in human brain: Implications for brain imaging studies. |date=05.2020 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co-receptor family in the developing feline gut. |date=09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24834895 |full-text-url=https://sci-hub.do/10.1016/j.aanat.2014.03.001 }} ==KLF4== * {{medline-title |title=Extracellular Vesicles from Healthy Cells Improves Cell Function and Stemness in Premature Senescent Stem Cells by miR-302b and HIF-1α Activation. |date=25.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32630449 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357081 }} * {{medline-title |title=Soluble klotho regulates the function of salivary glands by activating [[KLF4]] pathways. |date=02.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31581134 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814581 }} * {{medline-title |title=Centenarians Overexpress Pluripotency-Related Genes. |date=16.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797 |full-text-url=https://sci-hub.do/10.1093/gerona/gly168 }} * {{medline-title |title=A 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{{medline-title |title=Role of CD133 Molecule in Wnt Response and Renal Repair. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29431914 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827750 }} * {{medline-title |title=Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence. |date=15.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29138277 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733499 }} * {{medline-title |title=[[ZSCAN10]] expression corrects the genomic instability of iPSCs from aged donors. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28846095 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843481 }} * {{medline-title |title=Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts. |date=01.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28635509 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|title=[[KLF4]] deletion alters gastric cell lineage and induces [[MUC2]] expression. |date=09.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27277677 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143387 }} * {{medline-title |title=Critical role of the miR-200 family in regulating differentiation and proliferation of neurons. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25753155 |full-text-url=https://sci-hub.do/10.1111/jnc.13089 }} * {{medline-title |title=Oxidative DNA damage causes premature senescence in mouse embryonic fibroblasts deficient for Krüppel-like factor 4. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24788960 |full-text-url=https://sci-hub.do/10.1002/mc.22161 }} ==LPO== * {{medline-title |title=[Features of the changes in lipid peroxidation and activity of Na /K -ATPase in the brain of the aged rats in the conditions of two-vessel cerebral ischemia/reperfusion.] |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32160433 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{{medline-title |title=Gender, age-related, and regional differences of the magnetization transfer ratio of the cortical and subcortical brain gray matter. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24923993 |full-text-url=https://sci-hub.do/10.1002/jmri.24355 }} * {{medline-title |title=Age independently affects myelin integrity as detected by magnetization transfer magnetic resonance imaging in multiple sclerosis. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24936415 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053639 }} * {{medline-title |title=Magnetization transfer imaging for in vivo detection of microstructural tissue changes in aging and dementia: a short literature review. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24840568 |full-text-url=https://sci-hub.do/10.3233/JAD-132750 }} * {{medline-title |title=Quantitative multi-modal MRI of the Hippocampus and cognitive ability in community-dwelling older subjects. |date=04.2014 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|full-text-url=https://sci-hub.do/10.1007/s00395-015-0506-5 }} * {{medline-title |title=[[NOX4]] NADPH Oxidase-Dependent Mitochondrial Oxidative Stress in Aging-Associated Cardiovascular Disease. |date=20.12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26054376 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692134 }} * {{medline-title |title=The imbalanced redox status in senescent endothelial cells is due to dysregulated Thioredoxin-1 and NADPH oxidase 4. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24632182 |full-text-url=https://sci-hub.do/10.1016/j.exger.2014.03.005 }} ==PARP1== * {{medline-title |title=Topological DNA damage, telomere attrition and T cell senescence during chronic viral infections. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285747 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591813 }} * {{medline-title |title=[[PARP1]] inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells 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controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1. |date=03.06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24843141 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050581 }} ==ADAM10== * {{medline-title |title=NKG2D Ligand Shedding in Response to Stress: Role of [[ADAM10]]. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32269567 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109295 }} * {{medline-title |title=Chronic Mild Stress Modified Epigenetic Mechanisms Leading to Accelerated Senescence and Impaired Cognitive Performance in Mice. |date=10.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32050516 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037343 }} * {{medline-title |title=Removal of p75 Neurotrophin Receptor Expression from Cholinergic Basal Forebrain Neurons Reduces Amyloid-β Plaque Deposition and Cognitive Impairment in Aged APP/PS1 Mice. |date=07.2019 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|date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25980748 |full-text-url=https://sci-hub.do/10.1016/j.ejso.2015.04.006 }} * {{medline-title |title=Double negative (CD19 IgG IgD-[[CD27]]-) B lymphocytes: a new insight from telomerase in healthy elderly, in centenarian offspring and in Alzheimer's disease patients. |date=11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951896 |full-text-url=https://sci-hub.do/10.1016/j.imlet.2014.06.003 }} * {{medline-title |title=Memory B cells form in aged mice despite impaired affinity maturation and germinal center kinetics. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24389058 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989373 }} ==CD19== * {{medline-title |title=Sequential treatment with aT19 cells generates memory CAR-T cells and prolongs the lifespan of Raji-B-NDG mice. |date=28.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31634527 |full-text-url=https://sci-hub.do/10.1016/j.canlet.2019.10.022 }} * {{medline-title |title=Stress-Induced Premature Senescence Promotes Proliferation by Activating the [i]SENEX[/i] and p16 /Retinoblastoma (Rb) Pathway in Diffuse Large B-Cell Lymphoma |date=18.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327185 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863019 }} * {{medline-title |title=Effects of pepsin and pepstatin on reflux tonsil hypertrophy in vitro. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30408092 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224077 }} * {{medline-title |title=Innate and adaptive immune dysregulation in critically ill ICU patients. |date=05.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29976949 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033948 }} * {{medline-title |title=Vitamin D levels correlate with lymphocyte subsets in elderly patients with age-related diseases. |date=16.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769621 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|title=Pneumolysin induces cellular senescence by increasing ROS production and activation of MAPK/NF-κB signal pathway in glial cells. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28232188 |full-text-url=https://sci-hub.do/10.1016/j.toxicon.2017.02.017 }} * {{medline-title |title=The protein-interaction network with functional roles in tumorigenesis, neurodegeneration, and aging. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27699588 |full-text-url=https://sci-hub.do/10.1007/s11010-016-2836-5 }} * {{medline-title |title=A steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1. |date=27.09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27542238 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325331 }} * {{medline-title |title=Hyaluronan synthase 2 regulates fibroblast senescence in pulmonary fibrosis. |date=09.2016 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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32504508 |full-text-url=https://sci-hub.do/10.2174/1871530320666200606225357 }} * {{medline-title |title=Astrocyte senescence may drive alterations in GFAPα, CDKN2A p14 , and TAU3 transcript expression and contribute to cognitive decline. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31654269 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885035 }} * {{medline-title |title=Dietary Spray-Dried Porcine Plasma Prevents Cognitive Decline in Senescent Mice and Reduces Neuroinflammation and Oxidative Stress. |date=01.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31562503 |full-text-url=https://sci-hub.do/10.1093/jn/nxz239 }} * {{medline-title |title=Age-dependent hepatic alterations induced by a high-fat high-fructose diet. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30874869 |full-text-url=https://sci-hub.do/10.1007/s00011-019-01223-1 }} * {{medline-title |title=[i]Lactobacillus paracasei[/i] PS23 decelerated age-related muscle loss by ensuring mitochondrial function in SAMP8 mice. |date=29.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696799 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366975 }} * {{medline-title |title=Inflammatory cytokines and immune system modulation by aerobic versus resisted exercise training for elderly. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29977265 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016983 }} * {{medline-title |title=Pentoxifylline, dexamethasone and azithromycin demonstrate distinct age-dependent and synergistic inhibition of TLR- and inflammasome-mediated cytokine production in human newborn and adult blood in vitro. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29715306 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929513 }} * {{medline-title |title=Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia. |date=01.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29122767 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756472 }} * {{medline-title |title=The role of gender and labour status in immunosenescence of 65 Polish population. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28444479 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514219 }} * {{medline-title |title=Serum Immune Mediators Independently Associate with Atherosclerosis in the Left (But Not Right) Carotid Territory of Older Individuals. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27554076 |full-text-url=https://sci-hub.do/10.1016/j.jstrokecerebrovasdis.2016.07.047 }} * {{medline-title |title=[[IL10]]-driven [[STAT3]] signalling in senescent macrophages promotes pathological eye angiogenesis. |date=11.08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26260587 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918330 }} * {{medline-title |title=Development of depressive symptoms post hip fracture is associated with altered immunosuppressive phenotype in regulatory T and B lymphocytes. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26112234 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723613 }} * {{medline-title |title=LIPID PROFILE AND CYTOKINES INTERACTIONS DURING SUCCESSFUL AGING. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26087730 }} * {{medline-title |title=The effect of astaxanthin on the aging rat brain: gender-related differences in modulating inflammation. |date=30.01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25678261 |full-text-url=https://sci-hub.do/10.1002/jsfa.7131 }} * {{medline-title |title=Candidate SNP associations of optimism and resilience in older adults: exploratory study of 935 community-dwelling adults. |date=10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24791650 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163500 }} * {{medline-title |title=Oral delivery of glutamic acid decarboxylase (GAD)-65 and [[IL10]] by Lactococcus lactis reverses diabetes in recent-onset NOD mice. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24677716 |full-text-url=https://sci-hub.do/10.2337/db13-1236 }} ==INS== * {{medline-title |title=Melatonin protects [[INS]]-1 pancreatic β-cells from apoptosis and senescence induced by glucotoxicity and glucolipotoxicity. |date=03.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32673151 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527021 }} * {{medline-title |title=Nicotine triggers islet β cell senescence to facilitate the progression of type 2 diabetes. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32473187 |full-text-url=https://sci-hub.do/10.1016/j.tox.2020.152502 }} * {{medline-title |title=Reducing [[INS]]-[[IGF1]] signaling protects against non-cell autonomous vesicle rupture caused by [[SNCA]] spreading. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31354022 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144869 }} * {{medline-title |title=Insulin-like peptides and the mTOR-[[TFEB]] pathway protect [i]Caenorhabditis elegans[/i] hermaphrodites from mating-induced death. |date=08.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31282862 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697448 }} * {{medline-title |title=The Maghreb demographic transition: Tunisia case study. |date=10-11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30746669 }} * {{medline-title |title=Temporal pattern of neuronal insulin release during Caenorhabditis elegans aging: Role of redox homeostasis. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30456853 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351846 }} * {{medline-title |title=A functional study of all 40 [i]Caenorhabditis elegans[/i] insulin-like peptides. |date=26.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30206121 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204898 }} * {{medline-title |title=The anti-aging protein Klotho is induced by GABA therapy and exerts protective and stimulatory effects on pancreatic beta cells. |date=02.12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28993191 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.10.029 }} * {{medline-title |title=Increase of Calcium Sensing Receptor Expression Is Related to Compensatory Insulin Secretion during Aging in Mice. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27441644 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956240 }} * {{medline-title |title=Food-derived sensory cues modulate longevity via distinct neuroendocrine insulin-like peptides. |date=01.05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27125673 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863736 }} * {{medline-title |title=Resveratrol attenuates senescence of adipose-derived mesenchymal stem cells and restores their paracrine effects on promoting insulin secretion of [[INS]]-1 cells through Pim-1. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27049278 }} * {{medline-title |title=Accommodative movements of the lens/capsule and the strand that extends between the posterior vitreous zonule insertion zone
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