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* [[Aging genes 10|Genes with 10 and more publications]] * [[Aging genes 5-9|Genes with 5-9 publications]] * [[Aging genes 1-4|Genes with 1-4 publications]] ==CD4== * {{medline-title |title=Identification of Key Genes and Potential New Biomarkers for Ovarian Aging: A Study Based on RNA-Sequencing Data. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33304387 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701310 }} * {{medline-title |title=Distinct Age-Related Epigenetic Signatures in [[CD4]] and CD8 T Cells. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33262764 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686576 }} * {{medline-title |title=IL-1β-MyD88-mTOR Axis Promotes Immune-Protective IL-17A Foxp3 Cells During Mucosal Infection and Is Dysregulated With Aging. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33240286 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677307 }} * {{medline-title |title=Thymus involution sets the clock of declined immunity and repair with aging. |date=25.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33248315 |full-text-url=https://sci-hub.do/10.1016/j.arr.2020.101231 }} * {{medline-title |title=Food insecurity and T-cell dysregulation in women living with HIV on antiretroviral therapy. |date=28.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33247896 |full-text-url=https://sci-hub.do/10.1093/cid/ciaa1771 }} * {{medline-title |title=Rapamycin Eyedrops Increased [[CD4]] Foxp3 Cells and Prevented Goblet Cell Loss in the Aged Ocular Surface. |date=24.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33255287 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727717 }} * {{medline-title |title=Antioxidants N-Acetylcysteine and Vitamin C Improve T Cell Commitment to Memory and Long-Term Maintenance of Immunological Memory in Old Mice. |date=19.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33228213 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699597 }} * {{medline-title |title=Evolution of comorbidities in people living with HIV between 2004 and 2014: cross-sectional analyses from ANRS CO3 Aquitaine cohort. |date=16.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33198667 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670698 }} * {{medline-title |title=Impact of age on [[CD4]] recovery and viral suppression over time among adults living with HIV who initiated antiretroviral therapy in the African Cohort Study. |date=12.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33183355 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664082 }} * {{medline-title |title=hPMSCs protects against D-galactose-induced oxidative damage of [[CD4]] T cells through activating Akt-mediated Nrf2 antioxidant signaling. |date=04.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33148324 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641865 }} * {{medline-title |title=Substantial gap in primary care: older adults with HIV presenting late to care. |date=31.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33129258 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603686 }} * {{medline-title |title=Quantitative Digitography Measures Fine Motor Disturbances in Chronically Treated HIV Similar to Parkinson's Disease. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33132893 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575770 }} * {{medline-title |title=Monocyte and T Cell Immune Phenotypic Profiles Associated With Age Advancement Differ Between People With HIV, Lifestyle-Comparable Controls and Blood Donors. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33123168 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573236 }} * {{medline-title |title=HIV and three dimensions of Wisdom: Association with cognitive function and physical and mental well-being: For: Psychiatry Research. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33096437 |full-text-url=https://sci-hub.do/10.1016/j.psychres.2020.113510 }} * {{medline-title |title=CD8 T cells are present at low levels in the white matter with physiological and pathological aging. |date=13.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33049712 |full-text-url=https://sci-hub.do/10.18632/aging.104043 }} * {{medline-title |title=Immunotherapy in older patients with cancer. |date=26.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33041248 |full-text-url=https://sci-hub.do/10.1016/j.bj.2020.07.009 }} * {{medline-title |title=Multiple genetic programs contribute to [[CD4]] T cell memory differentiation and longevity by maintaining T cell quiescence. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32987276 |full-text-url=https://sci-hub.do/10.1016/j.cellimm.2020.104210 }} * {{medline-title |title=Conventional Treatment for Multiple Myeloma Drives Premature Aging Phenotypes and Metabolic Dysfunction in T Cells. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013907 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494758 }} * {{medline-title |title=Immunosenescence: the role of age in multiple sclerosis. |date=19.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32962809 |full-text-url=https://sci-hub.do/10.1016/j.nrl.2020.05.016 }} * {{medline-title |title=Umbilical cord mesenchymal stem cells protect thymus structure and function in aged C57 mice by downregulating aging-related genes and upregulating autophagy- and anti-oxidative stress-related genes. |date=14.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32924972 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521525 }} * {{medline-title |title=Impaired Cytotoxic CD8 T Cell Response in Elderly COVID-19 Patients. |date=18.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32948688 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502863 }} * {{medline-title |title=What are the roles of antibodies versus a durable, high quality T-cell response in protective immunity against SARS-CoV-2? |date=11.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32875286 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452821 }} * {{medline-title |title=Per2 Upregulation in Circulating Hematopoietic Progenitor Cells During Chronic HIV Infection. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850472 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396677 }} * {{medline-title |title=COVID-19: age, Interleukin-6, C-reactive protein, and lymphocytes as key clues from a multicentre retrospective study. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32802142 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426672 }} * {{medline-title |title=Immunosenescence profiles are not associated with muscle strength, physical performance and sarcopenia risk in very old adults: The Newcastle 85+ Study. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32735896 |full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111321 }} * {{medline-title |title=Homeostasis and the functional roles of [[CD4]] Treg cells in aging. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32717201 |full-text-url=https://sci-hub.do/10.1016/j.imlet.2020.07.004 }} * {{medline-title |title=A Comprehensive Evaluation of the Impact of Bovine Milk Containing Different Beta-Casein Profiles on Gut Health of Ageing Mice. |date=19.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32707687 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400800 }} * {{medline-title |title=Premature aging of circulating T cells predicts all-cause mortality in hemodialysis patients. |date=13.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32660510 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359274 }} * {{medline-title |title=In-depth immune cellular profiling reveals sex-specific associations with frailty. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32582361 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310472 }} * {{medline-title |title=CD70 contributes to age-associated T cell defects and overwhelming inflammatory responses. |date=19.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32559178 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343466 }} * {{medline-title |title=Comparison of Overall and Comorbidity-Free Life Expectancy Between Insured Adults With and Without HIV Infection, 2000-2016. |date=01.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32539152 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296391 }} * {{medline-title |title=Comparative Analysis of Age-Related Changes in Lacrimal Glands and Meibomian Glands of a C57BL/6 Male Mouse Model. |date=11.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32545199 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313015 }} * {{medline-title |title=Thymus aging in mice deficient in either EphB2 or EphB3, two master regulators of thymic epithelium development. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32506584 |full-text-url=https://sci-hub.do/10.1002/dvdy.212 }} * {{medline-title |title=CD8 T-cell senescence and skewed lymphocyte subsets in young Dyskeratosis Congenita patients with PARN and DKC1 mutations. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32452087 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521304 }} * {{medline-title |title=Short-Term Environmental Enrichment is a Stronger Modulator of Brain Glial Cells and Cervical Lymph Node T Cell Subtypes than Exercise or Combined Exercise and Enrichment. |date=25.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32451728 |full-text-url=https://sci-hub.do/10.1007/s10571-020-00862-x }} * {{medline-title |title=Viral and host factors related to the clinical outcome of COVID-19. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32434211 |full-text-url=https://sci-hub.do/10.1038/s41586-020-2355-0 }} * {{medline-title |title=Use of comedications and potential drug-drug interactions in people living with HIV in China. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32354599 |full-text-url=https://sci-hub.do/10.1016/j.jiac.2020.04.003 }} * {{medline-title |title=[[CD4]] T helper 17 cell response of aged mice promotes prostate cancer cell migration and invasion. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32356608 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310589 }} * {{medline-title |title=The Rules of Human T Cell Fate [i]in vivo[/i]. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32322253 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156550 }} * {{medline-title |title=[[CD4]]/CD8 ratio, comorbidities, and aging in treated HIV infected individuals on viral suppression. |date=21.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32314818 |full-text-url=https://sci-hub.do/10.1002/jmv.25911 }} * {{medline-title |title=The effects of advanced maternal age on T-cell subsets at the maternal-fetal interface prior to term labor and in the offspring: a mouse study. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32279324 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290081 }} * {{medline-title |title=Structural and Functional Changes in the Mesenteric Lymph Nodes in Humans during Aging. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32248450 |full-text-url=https://sci-hub.do/10.1007/s10517-020-04782-0 }} * {{medline-title |title=Neurocognitive Functioning is Associated with Self-Reported and Performance-Based Treatment Management Abilities in People Living with HIV with Low Health Literacy. |date=24.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32090235 |full-text-url=https://sci-hub.do/10.1093/arclin/acaa005 }} * {{medline-title |title=Blockade of Stat3 oncogene addiction induces cellular senescence and reveals a cell-nonautonomous activity suitable for cancer immunotherapy. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32064174 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996562 }} * {{medline-title |title=Age-related changes in T lymphocytes of patients with head and neck squamous cell carcinoma. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32082401 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017629 }} * {{medline-title |title=Immunological history governs human stem cell memory [[CD4]] heterogeneity via the Wnt signaling pathway. |date=10.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32041953 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010798 }} * {{medline-title |title=Estimating HIV Management and Comorbidity Costs Among Aging HIV Patients in the United States: A Systematic Review. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32011956 |full-text-url=https://sci-hub.do/10.18553/jmcp.2020.26.2.104 }} * {{medline-title |title=Sex Differences in People Aging With HIV. |date=01.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32032279 |full-text-url=https://sci-hub.do/10.1097/QAI.0000000000002259 }} * {{medline-title |title=Identification of Differentially Expressed miRNAs in the Response of Spleen [[CD4]] T Cells to Electroacupuncture in Senescence-Accelerated Mice. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32026263 |full-text-url=https://sci-hub.do/10.1007/s12013-020-00900-x }} * {{medline-title |title=Thymus Involution and Intravenous Drug Abuse. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32000220 |full-text-url=https://sci-hub.do/10.1097/PAF.0000000000000530 }} * {{medline-title |title=Depletion of [[CD4]] T cells provides therapeutic benefits in aged mice after ischemic stroke. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31954116 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059209 }} * {{medline-title |title=Immunological and Virological Responses in Older HIV-Infected Adults Receiving Antiretroviral Therapy: An Evidence-Based Meta-Analysis. |date=01.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31913990 |full-text-url=https://sci-hub.do/10.1097/QAI.0000000000002266 }} * {{medline-title |title=African Mitochondrial DNA Haplogroup L2 Is Associated With Slower Decline of β-cell Function and Lower Incidence of Diabetes Mellitus in Non-Hispanic, Black Women Living With Human Immunodeficiency Virus. |date=05.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31927570 |full-text-url=https://sci-hub.do/10.1093/cid/ciaa026 }} * {{medline-title |title=DP1 Activation Reverses Age-Related Hypertension Via NEDD4L-Mediated T-Bet Degradation in T Cells. |date=25.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31893939 |full-text-url=https://sci-hub.do/10.1161/CIRCULATIONAHA.119.042532 }} * {{medline-title |title=An Emerging Concern-High Rates of Frailty among Middle-aged and Older Individuals Living with HIV. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31885759 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887139 }} * {{medline-title |title=Higher Acuity Resource Utilization With Older Age and Poorer HIV Control in Adolescents and Young Adults in the HIV Research Network. |date=01.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31904706 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055514 }} * {{medline-title |title=Mitochondrial DNA Haplogroups and Frailty in Adults Living with HIV. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31822125 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133433 }} * {{medline-title |title=Gallic acid attenuates thymic involution in the d-galactose induced accelerated aging mice. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31822433 |full-text-url=https://sci-hub.do/10.1016/j.imbio.2019.11.005 }} * {{medline-title |title=Mitochondrial mass governs the extent of human T cell senescence. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31788930 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996952 }} * {{medline-title |title=T cells and immune functions of plasma extracellular vesicles are differentially modulated from adults to centenarians. |date=27.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31785146 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914389 }} * {{medline-title |title=Defects in Antiviral T Cell Responses Inflicted by Aging-Associated miR-181a Deficiency. |date=19.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31747595 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957231 }} * {{medline-title |title=Increased Prevalence of Neurocognitive Impairment in Aging People Living With Human Immunodeficiency Virus: The ANRS EP58 HAND 55-70 Study. |date=10.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31755936 |full-text-url=https://sci-hub.do/10.1093/cid/ciz670 }} * {{medline-title |title=Age-associated changes in human [[CD4]] T cells point to mitochondrial dysfunction consequent to impaired autophagy. |date=09.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31707363 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874450 }} * {{medline-title |title=Sex Differences in the Blood Transcriptome Identify Robust Changes in Immune Cell Proportions with Aging and Influenza Infection. |date=12.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31722210 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856718 }} * {{medline-title |title=Going Beyond Giving Antiretroviral Therapy: Multimorbidity in Older People Aging with HIV in Nigeria. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31711310 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071065 }} * {{medline-title |title=Alterations in composition of immune cells and impairment of anti-tumor immune response in aged oral cancer-bearing mice. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31683168 |full-text-url=https://sci-hub.do/10.1016/j.oraloncology.2019.104462 }} * {{medline-title |title=LTA1 is a safe, intranasal enterotoxin-based adjuvant that improves vaccine protection against influenza in young, old and B-cell-depleted (μMT) mice. |date=22.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31641151 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805908 }} * {{medline-title |title=Thymus Imaging Detection and Size Is Inversely Associated With Metabolic Syndrome and Frailty in People With HIV. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31660382 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6809752 }} * {{medline-title |title=Alterations in peripheral T cell and B cell subsets in patients with osteoarthritis. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31624962 |full-text-url=https://sci-hub.do/10.1007/s10067-019-04768-y }} * {{medline-title |title=Short Communication: Carotid Intima-Media Thickness Is Not Associated with Neurocognitive Impairment Among People Older than 50 Years With and Without HIV Infection from Thailand. |date=11-12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31588776 |full-text-url=https://sci-hub.do/10.1089/AID.2019.0139 }} * {{medline-title |title=Implications of Immune Checkpoint Expression During Aging in HIV-Infected People on Antiretroviral Therapy. |date=11-12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31578868 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862963 }} * {{medline-title |title=Age-related alterations in human gut [[CD4]] T cell phenotype, T helper cell frequencies, and functional responses to enteric bacteria. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31573727 |full-text-url=https://sci-hub.do/10.1002/JLB.5A0919-177RR }} * {{medline-title |title=Determinants of blood telomere length in antiretroviral treatment-naïve HIV-positive participants enrolled in the NEAT 001/ANRS 143 clinical trial. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31532902 |full-text-url=https://sci-hub.do/10.1111/hiv.12791 }} * {{medline-title |title=Human T Cell Differentiation Negatively Regulates Telomerase Expression Resulting in Reduced Activation-Induced Proliferation and Survival. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31497023 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712505 }} * {{medline-title |title=Short Communication: Getting Older with HIV: Increasing Frequency of Comorbidities and Polypharmacy in Brazilian HIV Patients. |date=11-12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31452382 |full-text-url=https://sci-hub.do/10.1089/AID.2019.0069 }} * {{medline-title |title=Gait Speed Decline Is Associated with Hemoglobin A1C, Neurocognitive Impairment, and Black Race in Persons with HIV. |date=11-12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31468979 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862955 }} * {{medline-title |title=Noncommunicable Diseases Burden and Risk Factors in a Cohort of HIV+ Elderly Patients in Malawi. |date=11-12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31468993 |full-text-url=https://sci-hub.do/10.1089/AID.2019.0125 }} * {{medline-title |title=Aging promotes reorganization of the [[CD4]] T cell landscape toward extreme regulatory and effector phenotypes. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31457092 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703865 }} * {{medline-title |title=Prevalence of hypertension and cardiovascular risk factors among long-term AIDS survivors: A report from the field. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31448551 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896990 }} ==TNF== * {{medline-title |title=Naringenin alleviates nonalcoholic steatohepatitis in middle-aged Apoe mice: role of SIRT1. |date=18.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33234364 |full-text-url=https://sci-hub.do/10.1016/j.phymed.2020.153412 }} * {{medline-title |title=Protective role of microglial HO-1 blockade in aging: Implication of iron metabolism. |date=06.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33212416 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680814 }} * {{medline-title |title=Anti-aging effect of DL-β-hydroxybutyrate against hepatic cellular senescence induced by D-galactose or γ-irradiation via autophagic flux stimulation in male rats. |date=01-02.2021 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33147533 |full-text-url=https://sci-hub.do/10.1016/j.archger.2020.104288 }} * {{medline-title |title=Exploring the extensive crosstalk between the antagonistic cytokines- TGF-β and [[TNF]]-α in regulating cancer pathogenesis. |date=03.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33153895 |full-text-url=https://sci-hub.do/10.1016/j.cyto.2020.155348 }} * {{medline-title |title=Long non-coding RNA SNHG29 regulates cell senescence via p53/p21 signaling in spontaneous preterm birth. |date=15.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33080448 |full-text-url=https://sci-hub.do/10.1016/j.placenta.2020.10.009 }} * {{medline-title |title=Cognition Is Associated With Peripheral Immune Molecules in Healthy Older Adults: A Cross-Sectional Study. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32983153 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493640 }} * {{medline-title |title=Anti-aging effects of [i]Ribes meyeri[/i] anthocyanins on neural stem cells and aging mice. |date=12.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32920547 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521483 }} * {{medline-title |title=Effects of a four week detraining period on physical, metabolic, and inflammatory profiles of elderly women who regularly participate in a program of strength training. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32863968 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450596 }} * {{medline-title |title=Contribution of Porphyromonas gingivalis lipopolysaccharide to experimental periodontitis in relation to aging. |date=26.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32851571 |full-text-url=https://sci-hub.do/10.1007/s11357-020-00258-1 }} * {{medline-title |title=New MoDC-Targeting [[TNF]] Fusion Proteins Enhance Cyclic Di-GMP Vaccine Adjuvanticity in Middle-Aged and Aged Mice. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32849581 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427090 }} * {{medline-title |title=Cognitive impairment in elderly patients with rheumatic disease and the effect of disease-modifying anti-rheumatic drugs. |date=30.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32862311 |full-text-url=https://sci-hub.do/10.1007/s10067-020-05372-1 }} * {{medline-title |title=Cotinine ameliorates memory and learning impairment in senescent mice. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32818583 |full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2020.08.010 }} * {{medline-title |title=Kynurenines link chronic inflammation to functional decline and physical frailty. |date=20.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32814718 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455140 }} * {{medline-title |title=Voluntary exercise training attenuated the middle-aged maturity-induced cardiac apoptosis. |date=15.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32781061 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118187 }} * {{medline-title |title=Preclinical Evaluation of a Food-Derived Functional Ingredient to Address Skeletal Muscle Atrophy. |date=29.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32751276 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469066 }} * {{medline-title |title=Childhood survivors of high-risk neuroblastoma show signs of immune recovery and not immunosenescence. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32744364 |full-text-url=https://sci-hub.do/10.1002/eji.202048541 }} * {{medline-title |title=FK506 induces lung lymphatic endothelial cell senescence and downregulates LYVE-1 expression, with associated decreased hyaluronan uptake. |date=31.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32736525 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395348 }} * {{medline-title |title=Late-onset hypogonadism: Reductio ad absurdum of the cardiovascular risk-benefit of testosterone replacement therapy. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32737921 |full-text-url=https://sci-hub.do/10.1111/andr.12876 }} * {{medline-title |title=Doxorubicin generates senescent microglia that exhibit altered proteomes, higher levels of cytokine secretion, and a decreased ability to internalize amyloid β. |date=15.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32738344 |full-text-url=https://sci-hub.do/10.1016/j.yexcr.2020.112203 }} * {{medline-title |title=Time restricted feeding provides a viable alternative to alternate day fasting when evaluated in terms of redox homeostasis in rats. |date=16.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32717588 |full-text-url=https://sci-hub.do/10.1016/j.archger.2020.104188 }} * {{medline-title |title=Associations Between Plasma Immunomodulatory and Inflammatory Mediators With VACS Index Scores Among Older HIV-Infected Adults on Antiretroviral Therapy. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32695109 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338430 }} * {{medline-title |title=Chrysin Impact on Oxidative and Inflammation Damages in the Liver of Aged Male Rats. |date=17.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32679027 |full-text-url=https://sci-hub.do/10.2174/1871530320666200717162304 }} * {{medline-title |title=Correction of immunosuppression in aged septic rats by human ghrelin and growth hormone through the vagus nerve-dependent inhibition of TGF-β production. |date=16.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32677895 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364485 }} * {{medline-title |title=Epigenetics of neuroinflammation: Immune response, inflammatory response and cholinergic synaptic involvement evidenced by genome-wide DNA methylation analysis of delirious inpatients. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32590150 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486988 }} * {{medline-title |title=[i]Andrographis paniculata[/i] and Its Bioactive Diterpenoids Against Inflammation and Oxidative Stress in Keratinocytes. |date=17.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32560449 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346124 }} * {{medline-title |title=Etanercept improves aging-induced cognitive deficits by reducing inflammation and vascular dysfunction in rats. |date=01.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32569601 |full-text-url=https://sci-hub.do/10.1016/j.physbeh.2020.113019 }} * {{medline-title |title=Bacterial antigen translocation and age as BMI-independent contributing factors on systemic inflammation in NAFLD patients. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32559006 |full-text-url=https://sci-hub.do/10.1111/liv.14571 }} * {{medline-title |title=Bone marrow mesenchymal stem cells improve thymus and spleen function of aging rats through affecting P21/PCNA and suppressing oxidative stress. |date=19.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32561691 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343510 }} * {{medline-title |title=Glycolic acid adjusted to pH 4 stimulates collagen production and epidermal renewal without affecting levels of proinflammatory [[TNF]]-alpha in human skin explants. |date=24.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32583600 |full-text-url=https://sci-hub.do/10.1111/jocd.13570 }} * {{medline-title |title=A20 of nucleus pulposus cells plays a self-protection role via the nuclear factor-kappa B pathway in the inflammatory microenvironment. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32566144 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284293 }} * {{medline-title |title=Age-associated decline in neural, endocrine, and immune responses in men and women: Involvement of intracellular signaling pathways. |date=15.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32563124 |full-text-url=https://sci-hub.do/10.1016/j.jneuroim.2020.577290 }} * {{medline-title |title=Classical and lectin complement pathways and markers of inflammation for investigation of susceptibility to infections among healthy older adults. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32536956 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285792 }} * {{medline-title |title=Activation of FoxO1/SIRT1/RANKL/OPG pathway may underlie the therapeutic effects of resveratrol on aging-dependent male osteoporosis. |date=12.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32532246 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293127 }} * {{medline-title |title=The senescence-associated secretome as an indicator of age and medical risk. |date=18.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32554926 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406245 }} * {{medline-title |title=Exercise Partially Rejuvenates Muscle Stem Cells. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32484032 |full-text-url=https://sci-hub.do/10.1089/rej.2020.2359 }} * {{medline-title |title=Brazilian berry extract (Myrciaria jaboticaba): A promising therapy to minimize prostatic inflammation and oxidative stress. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32460430 |full-text-url=https://sci-hub.do/10.1002/pros.24017 }} * {{medline-title |title=Potential therapeutic effects of endothelial cells trans-differentiated from Wharton's Jelly-derived mesenchymal stem cells on altered vascular functions in aged diabetic rat model. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32426041 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216374 }} * {{medline-title |title=[Effect of fragmented sleep on postoperative cognitive function and central neuroinflammation]. |date=05.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32375444 |full-text-url=https://sci-hub.do/10.3760/cma.j.cn112137-20191215-02734 }} * {{medline-title |title=Can blocking inflammation enhance immunity during aging? |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32386656 |full-text-url=https://sci-hub.do/10.1016/j.jaci.2020.03.016 }} * {{medline-title |title=[FAS- and [[TNF]]-dependent ways participation in apoptosis mechanisms in hypotalumus in physiological and pathological aging.] |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32362081 }} * {{medline-title |title=Ultrasound-guided continuous thoracic paravertebral block alleviates postoperative delirium in elderly patients undergoing esophagectomy: A randomized controlled trial. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32332664 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440095 }} * {{medline-title |title=17β-Estradiol improves insulin signalling and insulin resistance in the aged female hearts: Role of inflammatory and anti-inflammatory cytokines. |date=15.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32311377 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.117673 }} * {{medline-title |title=Synergistic Antitumor Efficacy of Magnetohyperthermia and Poly(lactic-co-glycolic acid)-Encapsulated Selol in Ehrlich Breast Adenocarcinoma Treatment in Elderly Swiss Mice. |date=01.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32252879 |full-text-url=https://sci-hub.do/10.1166/jbn.2020.2890 }} * {{medline-title |title=Pinitol suppresses [[TNF]]-α-induced chondrocyte senescence. |date=19.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32200264 |full-text-url=https://sci-hub.do/10.1016/j.cyto.2020.155047 }} * {{medline-title |title=[Aging of skin fibroblasts: genetic and epigenetic factors.] |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32160428 }} * {{medline-title |title=Functional and traditional training improve muscle power and reduce proinflammatory cytokines in older women: A randomized controlled trial. |date=01.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32151735 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110920 }} * {{medline-title |title=Associations of [[TNF]]-α -308 G>A and [[TNF]]-β 252 A>G with Physical Function and BNP-Rugao Longevity and Ageing Study. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32115620 |full-text-url=https://sci-hub.do/10.1007/s12603-020-1336-1 }} * {{medline-title |title=3D TECA hydrogel reduces cellular senescence and enhances fibroblasts migration in wound healing. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32104405 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032142 }} * {{medline-title |title=Regulatory Effect of Anwulignan on the Immune Function Through Its Antioxidation and Anti-Apoptosis in D-Galactose-Induced Aging Mice. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32099340 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996228 }} * {{medline-title |title=Pretreatment Frailty Is Independently Associated With Increased Risk of Infections After Immunosuppression in Patients With Inflammatory Bowel Diseases. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32105728 |full-text-url=https://sci-hub.do/10.1053/j.gastro.2020.02.032 }} * {{medline-title |title=The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of SIRT1. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32047577 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003265 }} * {{medline-title |title=In the Absence of a TCR Signal IL-2/IL-12/18-Stimulated γδ T Cells Demonstrate Potent Anti-Tumoral Function Through Direct Killing and Senescence Induction in Cancer Cells. |date=04.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31947966 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017313 }} * {{medline-title |title=Aging is associated with loss of beneficial effects of estrogen on leptin responsiveness in mice fed high fat diet: Role of estrogen receptor α and cytokines. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31904410 |full-text-url=https://sci-hub.do/10.1016/j.mad.2019.111198 }} * {{medline-title |title=Mitochondrial Dysfunction and Alpha-Lipoic Acid: Beneficial or Harmful in Alzheimer's Disease? |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31885820 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914903 }} * {{medline-title |title=Design, synthesis and evaluation of diosgenin carbamate derivatives as multitarget anti-Alzheimer's disease agents. |date=01.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31837501 |full-text-url=https://sci-hub.do/10.1016/j.ejmech.2019.111913 }} * {{medline-title |title=Oral Administration of Okara Soybean By-Product Attenuates Cognitive Impairment in a Mouse Model of Accelerated Aging. |date=03.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31816987 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950093 }} * {{medline-title |title=Electric vagal nerve stimulation inhibits inflammation and improves early postoperation cognitive dysfunction in aged rats. |date=23.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31759387 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875068 }} * {{medline-title |title=Metformin decreases LPS-induced inflammatory response in rabbit annulus fibrosus stem/progenitor cells by blocking HMGB1 release. |date=26.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31772144 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914423 }} * {{medline-title |title=The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling in vitro. |date=11.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31746877 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906224 }} * {{medline-title |title=Arsenic induces human chondrocyte senescence and accelerates rat articular cartilage aging. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31734849 |full-text-url=https://sci-hub.do/10.1007/s00204-019-02607-2 }} * {{medline-title |title=Bone Benefits of Fish Oil Supplementation Depend on its EPA and DHA Content. |date=08.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31717258 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893665 }} * {{medline-title |title=Inflammaging phenotype in rhesus macaques is associated with a decline in epithelial barrier-protective functions and increased pro-inflammatory function in CD161-expressing cells. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31713098 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925095 }} * {{medline-title |title=Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians. |date=26.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31719197 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883788 }} * {{medline-title |title=Gut microbiota combined with metabolomics reveals the metabolic profile of the normal aging process and the anti-aging effect of FuFang Zhenshu TiaoZhi(FTZ) in mice. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31704617 |full-text-url=https://sci-hub.do/10.1016/j.biopha.2019.109550 }} * {{medline-title |title=Intervertebral disc ageing and degeneration: The antiapoptotic effect of oestrogen. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31669486 |full-text-url=https://sci-hub.do/10.1016/j.arr.2019.100978 }} * {{medline-title |title=MicroRNA 16-5p is upregulated in calorie-restricted mice and modulates inflammatory cytokines of macrophages. |date=30.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31654705 |full-text-url=https://sci-hub.do/10.1016/j.gene.2019.144191 }} * {{medline-title |title=Aerobic exercise modulates cytokine profile and sleep quality in elderly. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31656505 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794533 }} * {{medline-title |title=Trehalose targets Nrf2 signal to alleviate d-galactose induced aging and improve behavioral ability. |date=01.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31630800 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.10.088 }} * {{medline-title |title=Anti-Inflammatory and Anti-Aging Evaluation of Pigment-Protein Complex Extracted from [i]Chlorella Pyrenoidosa[/i]. |date=16.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31623220 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836285 }} * {{medline-title |title=Inflammatory mediators and the risk of falls among older women with acute low back pain: data from Back Complaints in the Elders (BACE)-Brazil. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31606818 |full-text-url=https://sci-hub.do/10.1007/s00586-019-06168-x }} * {{medline-title |title=Acetylcholinesterase inhibitors targeting the cholinergic anti-inflammatory pathway: a new therapeutic perspective in aging-related disorders. |date=03.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31583530 |full-text-url=https://sci-hub.do/10.1007/s40520-019-01359-4 }} * {{medline-title |title=Study on Metabolic Trajectory of Liver Aging and the Effect of Fufang Zhenzhu Tiaozhi on Aging Mice. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31555127 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722462 }} * {{medline-title |title=Systemic Tumor Necrosis Factor-Alpha Trajectories Relate to Brain Health in Typically Aging Older Adults. |date=13.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31549145 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457183 }} * {{medline-title |title=Targeting senescence improves angiogenic potential of adipose-derived mesenchymal stem cells in patients with preeclampsia. |date=14.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31521202 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744626 }} * {{medline-title |title=Suppression of gut dysbiosis by Bifidobacterium longum alleviates cognitive decline in 5XFAD transgenic and aged mice. |date=14.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31413350 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694197 }} * {{medline-title |title=Moderate hyperoxia induces senescence in developing human lung fibroblasts. |date=01.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31411059 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879905 }} * {{medline-title |title=Aging-related carcinoembryonic antigen-related cell adhesion molecule 1 signaling promotes vascular dysfunction. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31389127 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826129 }} * {{medline-title |title=Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APP /PS1 Transgenic Mice. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31417357 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682662 }} * {{medline-title |title=Age- and diet-specific effects of chronic exposure to chlorpyrifos on hormones, inflammation and gut microbiota in rats. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31400786 |full-text-url=https://sci-hub.do/10.1016/j.pestbp.2019.05.018 }} ==HR== * {{medline-title |title=Patients with hip fracture and total hip arthroplasty surgery differ in anthropometric, but not cardiovascular screening abnormalities. |date=02.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33267795 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713041 }} * {{medline-title |title=Clinical Role of Lung Ultrasound for the Diagnosis and Prognosis of Coronavirus Disease Pneumonia in Elderly Patients: A Pivotal Study. |date=03.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33271558 |full-text-url=https://sci-hub.do/10.1159/000512209 }} * {{medline-title |title=The Relationship of Accelerometer-Assessed Standing Time With and Without Ambulation and Mortality: The WHI OPACH Study. |date=12.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33225345 |full-text-url=https://sci-hub.do/10.1093/gerona/glaa227 }} * {{medline-title |title=Age-related myofiber atrophy in old mice is reversed by ten weeks voluntary high-resistance wheel running. |date=09.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33181317 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111150 }} * {{medline-title |title=Predicted Skeletal Muscle Mass and 4-Year Cardiovascular Disease Incidence in Middle-Aged and Elderly Participants of IKARIA Prospective Epidemiological Study: The Mediating Effect of Sex and Cardiometabolic Factors. |date=27.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33121164 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693172 }} * {{medline-title |title=Obesity is associated with early hip fracture risk in postmenopausal women: a 25-year follow-up. |date=23.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33095419 |full-text-url=https://sci-hub.do/10.1007/s00198-020-05665-w }} * {{medline-title |title=ATM inhibition synergizes with fenofibrate in high grade serous ovarian cancer cells. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33024871 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527645 }} * {{medline-title |title=Effectiveness of adjuvant FOLFOX vs 5FU/LV in adults over age 65 with stage II and III colon cancer using a novel hybrid approach. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33015888 |full-text-url=https://sci-hub.do/10.1002/pds.5148 }} * {{medline-title |title=Age, Frailty, and Comorbidity as Prognostic Factors for Short-Term Outcomes in Patients With Coronavirus Disease 2019 in Geriatric Care. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32978065 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427570 }} * {{medline-title |title=Clinical and demographic parameters predict the progression from mild cognitive impairment to dementia in elderly patients. |date=12.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32918697 |full-text-url=https://sci-hub.do/10.1007/s40520-020-01697-8 }} * {{medline-title |title=Plasma Dehydroepiandrosterone Sulfate and Cardiovascular Disease Risk in Older Men and Women. |date=01.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32785663 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526732 }} * {{medline-title |title=High intensity interval training combined with L-citrulline supplementation: Effects on physical performance in healthy older adults. |date=15.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32721549 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111036 }} * {{medline-title |title=Associations of blood pressure with risk of injurious falls in old age vary by functional status: A cohort study. |date=15.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32738383 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111038 }} * {{medline-title |title=Epigenetic age acceleration and clinical outcomes in gliomas. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32692766 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373289 }} * {{medline-title |title=Do Stairs Inhibit Seniors Who Live on Upper Floors From Going Out? |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32666833 |full-text-url=https://sci-hub.do/10.1177/1937586720936588 }} * {{medline-title |title=Age-specific acute changes in carotid-femoral pulse wave velocity with head-up tilt. |date=07.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32634245 |full-text-url=https://sci-hub.do/10.1093/ajh/hpaa101 }} * {{medline-title |title=Pre-frailty status increases the risk of rehospitalization in patients after elective cardiac surgery without complication. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32531126 |full-text-url=https://sci-hub.do/10.1111/jocs.14550 }} * {{medline-title |title=Comparative Performance of Creatinine-Based GFR Estimation Equations in Exceptional Longevity: The Rugao Longevity and Ageing Study. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32546991 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266309 }} * {{medline-title |title=Sex-and race-specific associations of protein intake with change in muscle mass and physical function in older adults: the Health, Aging, and Body Composition (Health ABC) Study. |date=01.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32520344 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326591 }} * {{medline-title |title=Deterioration of bone microstructure by aging and menopause in Japanese healthy women: analysis by [[HR]]-pQCT. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32519249 |full-text-url=https://sci-hub.do/10.1007/s00774-020-01115-z }} * {{medline-title |title=Association between Low Protein Intake and Mortality in Patients with Type 2 Diabetes. |date=01.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32492838 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352318 }} * {{medline-title |title=CAUSES, mortality rates and risk factors of death in community-dwelling Europeans aged 50 years and over: Results from the Survey of Health, Ageing and Retirement in Europe 2013-2015. |date=07-08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32325305 |full-text-url=https://sci-hub.do/10.1016/j.archger.2020.104035 }} * {{medline-title |title=Estimation of Wave Condition Number From Pressure Waveform Alone and Its Changes With Advancing Age in Healthy Women and Men. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32328003 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161432 }} * {{medline-title |title=Extended in vitro culture of primary human mesenchymal stem cells downregulates Brca1-related genes and impairs DNA double-strand break recognition. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32333827 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327915 }} * {{medline-title |title=Effect of artificial dawn light on cardiovascular function, alertness, and balance in middle-aged and older adults. |date=13.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32307533 |full-text-url=https://sci-hub.do/10.1093/sleep/zsaa082 }} * {{medline-title |title=Heart Rate Performance Curve Is Dependent on Age, Sex, and Performance. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32300582 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144539 }} * {{medline-title |title=Physical activity trajectories, mortality, hospitalization, and disability in the Toledo Study of Healthy Aging. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32163233 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432572 }} * {{medline-title |title=U-Shaped Association of Plasma Testosterone, and no Association of Plasma Estradiol, with Incidence of Fractures in Men. |date=01.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32155267 |full-text-url=https://sci-hub.do/10.1210/clinem/dgaa115 }} * {{medline-title |title=Pregnancy-Related Bone Mineral and Microarchitecture Changes in Women Aged 30 to 45 Years. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32119748 |full-text-url=https://sci-hub.do/10.1002/jbmr.3998 }} * {{medline-title |title=Analysis of the world record time for combined father and son marathon. |date=01.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31917623 |full-text-url=https://sci-hub.do/10.1152/japplphysiol.00819.2019 }} * {{medline-title |title=Age-related reductions in heart rate variability do not worsen during exposure to humid compared to dry heat: A secondary analysis. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31934605 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949029 }} * {{medline-title |title=Efficacy and Safety of Dapagliflozin in the Elderly: Analysis From the DECLARE-TIMI 58 Study. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31843945 |full-text-url=https://sci-hub.do/10.2337/dc19-1476 }} * {{medline-title |title=Validity of Prediction Equations of Maximal Heart Rate in Physically Active Female Adolescents and the Role of Maturation. |date=13.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31766291 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915545 }} * {{medline-title |title=Base excision repair but not DNA double-strand break repair is impaired in aged human adipose-derived stem cells. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31782607 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996963 }} * {{medline-title |title=Urban-Rural Differences in Hip Fracture Mortality: A Nationwide NOREPOS Study. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31768493 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874178 }} * {{medline-title |title=Malnutrition as a Strong Predictor of the Onset of Sarcopenia. |date=27.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31783482 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950107 }} * {{medline-title |title=Acclimation to a thermoneutral environment abolishes age-associated alterations in heart rate and heart rate variability in conscious, unrestrained mice. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31776883 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031176 }} * {{medline-title |title=Long-term dementia risk prediction by the LIBRA score: A 30-year follow-up of the CAIDE study. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31736136 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003764 }} * {{medline-title |title=Kidney function and its association to imminent, short- and long-term fracture risk-a longitudinal study in older women. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31754754 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946753 }} * {{medline-title |title=Oxidatively Damaged DNA/RNA and 8-Isoprostane Levels Are Associated With the Development of Type 2 Diabetes at Older Age: Results From a Large Cohort Study. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31653645 |full-text-url=https://sci-hub.do/10.2337/dc19-1379 }} * {{medline-title |title=Associations of vigorous physical activity with all-cause, cardiovascular and cancer mortality among 64 913 adults. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31548909 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733336 }} * {{medline-title |title=Reduced cerebrovascular and cardioventilatory responses to intermittent hypoxia in elderly. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31557538 |full-text-url=https://sci-hub.do/10.1016/j.resp.2019.103306 }} * {{medline-title |title=Vestibulo-sympathetic reflex in patients with bilateral vestibular loss. |date=01.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31513442 |full-text-url=https://sci-hub.do/10.1152/japplphysiol.00466.2019 }} * {{medline-title |title=Heart rate and blood pressure in male Ts65Dn mice: a model to investigate cardiovascular responses in Down syndrome. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31496136 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732568 }} * {{medline-title |title=Body weight at 10 years of age and change in body composition between 8 and 10 years of age were related to survival in a longitudinal study of 39 Labrador retriever dogs. |date=09.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31500653 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734441 }} * {{medline-title |title=Dietary diversity offsets the adverse mortality risk among older indigenous Taiwanese. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31464406 |full-text-url=https://sci-hub.do/10.6133/apjcn.201909_28(3).0019 }} * {{medline-title |title=Independent and joint effects of vascular and cardiometabolic risk factor pairs for risk of all-cause dementia: a prospective population-based study. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31455442 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948010 }} * {{medline-title |title=Work Ability and Job Survival: Four-Year Follow-Up. |date=28.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31466415 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747402 }} * {{medline-title |title=Predictivity of bioimpedance phase angle for incident disability in older adults. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31436391 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015240 }} ==APOE== * {{medline-title |title=Polygenic risk score of longevity predicts longer survival across an age-continuum. |date=20.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33216869 |full-text-url=https://sci-hub.do/10.1093/gerona/glaa289 }} * {{medline-title |title=Association Between [[APOE]] Alleles and Change of Neuropsychological Tests in the Long Life Family Study. |date=17.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33216038 |full-text-url=https://sci-hub.do/10.3233/JAD-201113 }} * {{medline-title |title=The [[APOE]] gene cluster responds to air pollution factors in mice with coordinated expression of genes that differs by age in humans. |date=20.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33215813 |full-text-url=https://sci-hub.do/10.1002/alz.12230 }} * {{medline-title |title=Homozygosity in the [i][[APOE]][/i] 3 Polymorphism Is Associated With Less Depression and Higher Serum Low-Density Lipoprotein in Chinese Elderly Schizophrenics. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33178131 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593819 }} * {{medline-title |title=Effect of apolipoprotein E polymorphism on cognition and brain in the Cambridge Centre for Ageing and Neuroscience cohort. |date=01-12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33088920 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545750 }} * {{medline-title |title=Cardiovascular risk factors and [[APOE]]-ε4 status affect memory functioning in aging via changes to temporal stem diffusion. |date=18.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33070365 |full-text-url=https://sci-hub.do/10.1002/jnr.24734 }} * {{medline-title |title=[[APOE]] [i]ε[/i]4 and resting-state functional connectivity in racially/ethnically diverse older adults. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32999914 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508460 }} * {{medline-title |title=Predictors of Olfactory Decline in Aging: A Longitudinal Population-Based Study. |date=13.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32886741 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662159 }} * {{medline-title |title=When Culture Influences Genes: Positive Age Beliefs Amplify the Cognitive-Aging Benefit of [[APOE]] ε2. |date=14.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32835364 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489069 }} * {{medline-title |title=Age and the association between apolipoprotein E genotype and Alzheimer disease: A cerebrospinal fluid biomarker-based case-control study. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32817639 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446786 }} * {{medline-title |title=Estimating the potential for dementia prevention through modifiable risk factors elimination in the real-world setting: a population-based study. |date=07.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32767997 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414752 }} * {{medline-title |title=Machine learning-based estimation of cognitive performance using regional brain MRI markers: the Northern Manhattan Study. |date=01.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32740887 |full-text-url=https://sci-hub.do/10.1007/s11682-020-00325-3 }} * {{medline-title |title=Effects of an [[APOE]] Promoter Polymorphism on Fronto-Parietal Functional Connectivity During Nondemented Aging. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32694990 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338603 }} * {{medline-title |title=The relationship of parental longevity with the aging brain-results from UK Biobank. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32671621 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525531 }} * {{medline-title |title=Alzheimer's Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation. |date=30.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32610143 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422733 }} * {{medline-title |title=Relationships Between Plasma Lipids Species, Gender, Risk Factors, and Alzheimer's Disease. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32474467 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369125 }} * {{medline-title |title=Effects of sex, age, and apolipoprotein E genotype on hippocampal parenchymal fraction in cognitively normal older adults. |date=30.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32416384 |full-text-url=https://sci-hub.do/10.1016/j.pscychresns.2020.111107 }} * {{medline-title |title=Cognitive Health of Nonagenarians in Southern Italy: A Descriptive Analysis from a Cross-Sectional, Home-Based Pilot Study of Exceptional Longevity (Cilento Initiative on Aging Outcomes Or CIAO). |date=05.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32380778 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279440 }} * {{medline-title |title=Apolipoprotein E and Health in Older Men: The Concord Health and Ageing in Men Project. |date=25.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32342099 |full-text-url=https://sci-hub.do/10.1093/gerona/glaa105 }} * {{medline-title |title=CSF amyloid is a consistent predictor of white matter hyperintensities across the disease course from aging to Alzheimer's disease. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32305782 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.03.008 }} * {{medline-title |title=Association of Cardiovascular Risk Factors with Cerebral Perfusion in Whites and African Americans. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32310160 |full-text-url=https://sci-hub.do/10.3233/JAD-190360 }} * {{medline-title |title=Alzheimer's Risk Factors Age, [[APOE]] Genotype, and Sex Drive Distinct Molecular Pathways. |date=03.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32199103 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388065 }} * {{medline-title |title=Less agreeable, better preserved? A PET amyloid and MRI study in a community-based cohort. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32169357 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.02.004 }} * {{medline-title |title=Physical Activity as Moderator of the Association Between [[APOE]] and Cognitive Decline in Older Adults: Results from Three Longitudinal Cohort Studies. |date=25.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32110803 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518558 }} * {{medline-title |title=Longitudinal Maintenance of Cognitive Health in Centenarians in the 100-plus Study. |date=05.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32101309 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137688 }} * {{medline-title |title=Interaction of [[APOE]], cerebral blood flow, and cortical thickness in the entorhinal cortex predicts memory decline. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32048144 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165062 }} * {{medline-title |title=Determinants of mesial temporal lobe volume loss in older individuals with preserved cognition: a longitudinal PET amyloid study. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32057528 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.12.002 }} * {{medline-title |title=Long-term exposure to ambient air pollution, [[APOE]]-ε4 status, and cognitive decline in a cohort of older adults in northern Manhattan. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31926436 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024003 }} * {{medline-title |title=Evidence in support of chromosomal sex influencing plasma based metabolome vs [[APOE]] genotype influencing brain metabolome profile in humanized [[APOE]] male and female mice. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31917799 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952084 }} * {{medline-title |title=[[APOE]] region molecular signatures of Alzheimer's disease across races/ethnicities. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31813627 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064423 }} * {{medline-title |title=Varying Effects of [[APOE]] Alleles on Extreme Longevity in European Ethnicities. |date=13.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31724059 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330482 }} * {{medline-title |title=Prospective Evaluation of Cognitive Health and Related Factors in Elderly at Risk for Developing Alzheimer's Dementia: A Longitudinal Cohort Study. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31686098 |full-text-url=https://sci-hub.do/10.14283/jpad.2019.31 }} * {{medline-title |title=Association of Cardiovascular and Alzheimer's Disease Risk Factors with Intracranial Arterial Blood Flow in Whites and African Americans. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31658057 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081660 }} * {{medline-title |title=Is Ongoing Anticholinergic Burden Associated With Greater Cognitive Decline and Dementia Severity in Mild to Moderate Alzheimer's Disease? |date=17.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31613323 |full-text-url=https://sci-hub.do/10.1093/gerona/glz244 }} * {{medline-title |title=Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31630996 |full-text-url=https://sci-hub.do/10.1016/j.jalz.2019.07.018 }} * {{medline-title |title=Prospective Memory: Age related change is influenced by [[APOE]] genotype. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31578124 |full-text-url=https://sci-hub.do/10.1080/13825585.2019.1671305 }} * {{medline-title |title=Education Moderates the Relation Between [[APOE]] ɛ4 and Memory in Nondemented Non-Hispanic Black Older Adults. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31594222 |full-text-url=https://sci-hub.do/10.3233/JAD-190415 }} * {{medline-title |title=Apolipoprotein E ε4 allele effects on longitudinal cognitive trajectories are sex and age dependent. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31561966 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561018 }} * {{medline-title |title=Interactive effect of age and [[APOE]]-ε4 allele load on white matter myelin content in cognitively normal middle-aged subjects. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31520917 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742967 }} * {{medline-title |title=[[APOE]] modifies the interaction of entorhinal cerebral blood flow and cortical thickness on memory function in cognitively normal older adults. |date=15.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31493534 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819270 }} * {{medline-title |title=When time's arrow doesn't bend: [[APOE]]-ε4 influences episodic memory before old age. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31473197 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817416 }} * {{medline-title |title=Cognitive-Motor Integration Performance Is Affected by Sex, [[APOE]] Status, and Family History of Dementia. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31424400 |full-text-url=https://sci-hub.do/10.3233/JAD-190403 }} * {{medline-title |title=Associations among amyloid status, age, and longitudinal regional brain atrophy in cognitively unimpaired older adults. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31437719 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198229 }} * {{medline-title |title=Cognitive function and neuropathological outcomes: a forward-looking approach. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31435771 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851487 }} * {{medline-title |title=[[APOE]] gene-dependent BOLD responses to a breath-hold across the adult lifespan. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31408838 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699560 }} ==MSC== * {{medline-title |title=Rejuvenation of Senescent Endothelial Progenitor Cells by Extracellular Vesicles Derived From Mesenchymal Stromal Cells. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33294742 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691285 }} * {{medline-title |title=Extracellular vesicles derived from bone marrow mesenchymal stem cells enhance myelin maintenance after cortical injury in aged rhesus monkeys. |date=29.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33264634 |full-text-url=https://sci-hub.do/10.1016/j.expneurol.2020.113540 }} * {{medline-title |title=TPP1 Enhances the Therapeutic Effects of Transplanted Aged Mesenchymal Stem Cells in Infarcted Hearts via the MRE11/AKT Pathway. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33195247 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658181 }} * {{medline-title |title=Aging-Affected [[MSC]] Functions and Severity of Periodontal Tissue Destruction in a Ligature-Induced Mouse Periodontitis Model. |date=30.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143068 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663404 }} * {{medline-title |title=Human placenta-derived mesenchymal stem cells stimulate ovarian function via miR-145 and bone morphogenetic protein signaling in aged rats. |date=05.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33153492 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643421 }} * {{medline-title |title=Mesenchymal Stromal Cells as Critical Contributors to Tissue Regeneration. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33102483 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546871 }} * {{medline-title |title=The biology of human hair greying. |date=23.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32965076 |full-text-url=https://sci-hub.do/10.1111/brv.12648 }} * {{medline-title |title=[i]Tsc1[/i] Regulates the Proliferation Capacity of Bone-Marrow Derived Mesenchymal Stem Cells. |date=10.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32927859 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565438 }} * {{medline-title |title=The role of mitochondrial dysfunction in mesenchymal stem cell senescence. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32803322 |full-text-url=https://sci-hub.do/10.1007/s00441-020-03272-z }} * {{medline-title |title=Metabolic syndrome increases senescence-associated micro-RNAs in extracellular vesicles derived from swine and human mesenchymal stem/stromal cells. |date=12.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32787856 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425605 }} * {{medline-title |title=Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses. |date=22.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32699947 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375036 }} * {{medline-title |title=Functional crosstalk between mTORC1/p70S6K pathway and heterochromatin organization in stress-induced senescence of [[MSC]]s. |date=13.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32660632 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359252 }} * {{medline-title |title=Increased cellular senescence in the murine and human stenotic kidney: Effect of mesenchymal stem cells. |date=02.2021 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32657444 |full-text-url=https://sci-hub.do/10.1002/jcp.29940 }} * {{medline-title |title=Intrinsic Type 1 Interferon (IFN1) Profile of Uncultured Human Bone Marrow CD45 CD271 Multipotential Stromal Cells (BM-[[MSC]]s): The Impact of Donor Age, Culture Expansion and IFNα and IFNβ Stimulation. |date=15.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32679782 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399891 }} * {{medline-title |title=Facial rejuvenation using stem cell conditioned media combined with skin needling: A split-face comparative study. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32623814 |full-text-url=https://sci-hub.do/10.1111/jocd.13594 }} * {{medline-title |title=Mesenchymal Stem Cell Senescence and Rejuvenation: Current Status and Challenges. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32582691 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283395 }} * {{medline-title |title=The changing epigenetic landscape of Mesenchymal Stem/Stromal Cells during aging. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32445894 |full-text-url=https://sci-hub.do/10.1016/j.bone.2020.115440 }} * {{medline-title |title=Dual Role of Autophagy in Regulation of Mesenchymal Stem Cell Senescence. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32391362 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193103 }} * {{medline-title |title=Molecular Aspects of Adipose-Derived Stromal Cell Senescence in a Long-Term Culture: A Potential Role of Inflammatory Pathways. |date=01-12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32314614 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586277 }} * {{medline-title |title=Human Obesity Induces Dysfunction and Early Senescence in Adipose Tissue-Derived Mesenchymal Stromal/Stem Cells. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32274385 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113401 }} * {{medline-title |title=miR-155-5p inhibition rejuvenates aged mesenchymal stem cells and enhances cardioprotection following infarction. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32196916 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189985 }} * {{medline-title |title=Mesenchymal Stem Cell Derived Extracellular Vesicles in Aging. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32154253 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047768 }} * {{medline-title |title=Molecular Mechanisms Contributing to Mesenchymal Stromal Cell Aging. |date=21.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32098040 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072652 }} * {{medline-title |title=Inhibition of DNA Methyltransferase by RG108 Promotes Pluripotency-Related Character of Porcine Bone Marrow Mesenchymal Stem Cells. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32125888 |full-text-url=https://sci-hub.do/10.1089/cell.2019.0060 }} * {{medline-title |title=Extracellular Vesicles of Stem Cells to Prevent BRONJ. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32119600 |full-text-url=https://sci-hub.do/10.1177/0022034520906793 }} * {{medline-title |title=Ginsenoside Rg1 as an Effective Regulator of Mesenchymal Stem Cells. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32038244 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989539 }} * {{medline-title |title=The Importance of Stem Cell Senescence in Regenerative Medicine. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32026416 |full-text-url=https://sci-hub.do/10.1007/5584_2020_489 }} * {{medline-title |title=Control of mesenchymal stem cell biology by histone modifications. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32025282 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996187 }} * {{medline-title |title=Impact of mesenchymal stem cell senescence on inflammaging. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31964472 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061209 }} * {{medline-title |title=Late Rescue Therapy with Cord-Derived Mesenchymal Stromal Cells for Established Lung Injury in Experimental Bronchopulmonary Dysplasia. |date=15.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31918630 |full-text-url=https://sci-hub.do/10.1089/scd.2019.0116 }} * {{medline-title |title=Low-Level Radiofrequency Exposure Does Not Induce Changes in [[MSC]] Biology: An in vitro Study for the Prevention of NIR-Related Damage. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31908499 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927227 }} * {{medline-title |title=Macrophage migration inhibitory factor rejuvenates aged human mesenchymal stem cells and improves myocardial repair. |date=27.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31881006 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949107 }} * {{medline-title |title=Influence of olive oil and its components on mesenchymal stem cell biology. |date=26.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31875868 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904865 }} * {{medline-title |title=Epigenetic Regulation of Mesenchymal Stem Cell Homeostasis. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31866188 |full-text-url=https://sci-hub.do/10.1016/j.tcb.2019.11.006 }} * {{medline-title |title=Mesenchymal Stem Cells: Allogeneic [[MSC]] May Be Immunosuppressive but Autologous [[MSC]] Are Dysfunctional in Lupus Patients. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31799252 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874144 }} * {{medline-title |title=Effects of high glucose conditions on the expansion and differentiation capabilities of mesenchymal stromal cells derived from rat endosteal niche. |date=21.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31752674 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873668 }} * {{medline-title |title=Autophagy inhibits the mesenchymal stem cell aging induced by D-galactose through ROS/JNK/p38 signalling. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31675454 |full-text-url=https://sci-hub.do/10.1111/1440-1681.13207 }} * {{medline-title |title=Enhancing survival, engraftment, and osteogenic potential of mesenchymal stem cells. |date=26.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31692976 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828596 }} * {{medline-title |title=Mesenchymal stem cell senescence alleviates their intrinsic and seno-suppressive paracrine properties contributing to osteoarthritis development. |date=22.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31644429 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834426 }} * {{medline-title |title=Embryonic stem cell-derived extracellular vesicles enhance the therapeutic effect of mesenchymal stem cells. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31660081 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815953 }} * {{medline-title |title=Survival of aging CD264 and CD264 populations of human bone marrow mesenchymal stem cells is independent of colony-forming efficiency. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31612990 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906265 }} * {{medline-title |title=Differential effects of extracellular vesicles from aging and young mesenchymal stem cells in acute lung injury. |date=29.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31575829 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781978 }} * {{medline-title |title=Connexin43 is Dispensable for Early Stage Human Mesenchymal Stem Cell Adipogenic Differentiation But is Protective against Cell Senescence. |date=11.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31514306 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770901 }} * {{medline-title |title=Maintained Properties of Aged Dental Pulp Stem Cells for Superior Periodontal Tissue Regeneration. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31440385 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675537 }} ==SIRT1== * {{medline-title |title=Anthocyanins attenuate endothelial dysfunction through regulation of uncoupling of nitric oxide synthase in aged rats. |date=03.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33274583 |full-text-url=https://sci-hub.do/10.1111/acel.13279 }} * {{medline-title |title=Sirtuins and Their Implications in Neurodegenerative Diseases from a Drug Discovery Perspective. |date=05.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33280374 |full-text-url=https://sci-hub.do/10.1021/acschemneuro.0c00696 }} * {{medline-title |title=Effects of alpha-mangostin on memory senescence induced by high glucose in human umbilical vein endothelial cells. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33149857 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585532 }} * {{medline-title |title=[[SIRT1]] Activation Using CRISPR/dCas9 Promotes Regeneration of Human Corneal Endothelial Cells through Inhibiting Senescence. |date=04.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33158256 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694272 }} * {{medline-title |title=Histone Deacetylase [[SIRT1]], Smooth Muscle Cell Function, and Vascular Diseases. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33117155 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573826 }} * {{medline-title |title=6,4'-dihydroxy-7-methoxyflavanone protects against H O -induced cellular senescence by inducing [[SIRT1]] and inhibiting phosphatidylinositol 3-kinase/Akt pathway activation. |date=27.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33111210 |full-text-url=https://sci-hub.do/10.1007/s11010-020-03951-z }} * {{medline-title |title=Isoparvifuran isolated from Dalbergia odorifera attenuates H O -induced senescence of BJ cells through [[SIRT1]] activation and AKT/mTOR pathway inhibition. |date=30.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33010892 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.09.096 }} * {{medline-title |title=[[SIRT1]] Is the Target Gene for 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside Alleviating the HUVEC Senescence. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013385 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508177 }} * {{medline-title |title=The Role of Sirtuins in Kidney Diseases. |date=12.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32932720 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555196 }} * {{medline-title |title=The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32919015 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111090 }} * {{medline-title |title=Virus-Induced Asthma Exacerbations: [[SIRT1]] Targeted Approach. |date=13.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32823491 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464235 }} * {{medline-title |title=Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32793997 |full-text-url=https://sci-hub.do/10.1007/s10522-020-09896-6 }} * {{medline-title |title=Glucose restriction delays senescence and promotes proliferation of HUVECs via the AMPK/[[SIRT1]]-FOXA3-Beclin1 pathway. |date=01.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32768436 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111053 }} * {{medline-title |title=Therapeutic Effects of SRT2104 on Lung Injury in Rats with Emphysema via Reduction of Type II Alveolar Epithelial Cell Senescence. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32722945 |full-text-url=https://sci-hub.do/10.1080/15412555.2020.1797657 }} * {{medline-title |title=Latifolin Inhibits Oxidative Stress-Induced Senescence via Upregulation of [[SIRT1]] in Human Dermal Fibroblasts. |date=01.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32404543 |full-text-url=https://sci-hub.do/10.1248/bpb.b20-00094 }} * {{medline-title |title=SRT1720-induced activation of [[SIRT1]] alleviates vascular smooth muscle cell senescence through PKA-dependent phosphorylation of AMPKα at Ser485. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32421926 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327920 }} * {{medline-title |title=miR-128 plays a critical role in murine osteoclastogenesis and estrogen deficiency-induced bone loss. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32292498 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150474 }} * {{medline-title |title=Lymphocyte senescence in COPD is associated with decreased sirtuin 1 expression in steroid resistant pro-inflammatory lymphocytes. |date=01-12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32270742 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153179 }} * {{medline-title |title=Therapeutic effects of hydro-alcoholic leaf extract of Withania somnifera on age-induced changes in daily rhythms of Sirt1, Nrf2 and Rev-erbα in the SCN of male Wistar rats. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32249404 |full-text-url=https://sci-hub.do/10.1007/s10522-020-09875-x }} * {{medline-title |title=The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32214805 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084123 }} * {{medline-title |title=Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32158519 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048230 }} * {{medline-title |title=Spatiotemporal gating of [[SIRT1]] functions by O-GlcNAcylation is essential for liver metabolic switching and prevents hyperglycemia. |date=24.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32152092 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104039 }} * {{medline-title |title=Hydrogen Sulfide Inhibits Homocysteine-Induced Neuronal Senescence by Up-Regulation of [[SIRT1]]. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32132865 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053352 }} * {{medline-title |title=[[SIRT1]] and aging related signaling pathways. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32084459 |full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111215 }} * {{medline-title |title=Tropisetron protects against brain aging via attenuating oxidative stress, apoptosis and inflammation: The role of [[SIRT1]] signaling. |date=01.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32088214 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.117452 }} * {{medline-title |title=Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of [[SIRT1]] activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32056076 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206476 }} * {{medline-title |title=Deacetylation of MRTF-A by [[SIRT1]] defies senescence induced down-regulation of collagen type I in fibroblast cells. |date=01.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32061777 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sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1. |date=23.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31881011 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949053 }} * {{medline-title |title=The protective role of omentin-1 in IL-1β-induced chondrocyte senescence. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31852248 |full-text-url=https://sci-hub.do/10.1080/21691401.2019.1699803 }} * {{medline-title |title=The Lifespan Extension Ability of Nicotinic Acid Depends on Whether the Intracellular NAD Level Is Lower than the Sirtuin-Saturating Concentrations. |date=24.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31878234 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982340 }} * {{medline-title |title=Alpha-mangostin decreased cellular senescence in human umbilical vein endothelial cells. |date=06.2020 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lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31544977 |full-text-url=https://sci-hub.do/10.1002/jcp.29182 }} * {{medline-title |title=Plasma exosomes in OSA patients promote endothelial senescence: effect of long-term adherent continuous positive airway pressure. |date=13.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31552414 |full-text-url=https://sci-hub.do/10.1093/sleep/zsz217 }} * {{medline-title |title=Hydrogen Sulfide Inhibits High Glucose-Induced Neuronal Senescence by Improving Autophagic Flux [i]via[/i] Up-regulation of [[SIRT1]]. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31481873 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710442 }} * {{medline-title |title=Activation of the miR-34a-Mediated [[SIRT1]]/mTOR Signaling Pathway by Urolithin A Attenuates D-Galactose-Induced Brain Aging in Mice. |date=10.2019 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|full-text-url=https://sci-hub.do/10.1016/j.redox.2020.101623 }} * {{medline-title |title=Direct-Coupled Electroretinogram (DC-ERG) for Recording the Light-Evoked Electrical Responses of the Mouse Retinal Pigment Epithelium. |date=14.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32744516 |full-text-url=https://sci-hub.do/10.3791/61491 }} * {{medline-title |title=High-density lipoproteins are a potential therapeutic target for age-related macular degeneration. |date=25.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32737203 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521644 }} * {{medline-title |title=MTOR-initiated metabolic switch and degeneration in the retinal pigment epithelium. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32721041 |full-text-url=https://sci-hub.do/10.1096/fj.202000612R }} * {{medline-title |title=[i]Lactobacillus paracasei[/i] KW3110 Suppresses Inflammatory Stress-Induced Premature Cellular Senescence of Human Retinal 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|title=Retinal Pigment Epithelial Cells: The Unveiled Component in the Etiology of Prpf Splicing Factor-Associated Retinitis Pigmentosa. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31884616 |full-text-url=https://sci-hub.do/10.1007/978-3-030-27378-1_37 }} * {{medline-title |title=AMPK May Play an Important Role in the Retinal Metabolic Ecosystem. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31884657 |full-text-url=https://sci-hub.do/10.1007/978-3-030-27378-1_78 }} * {{medline-title |title=Stem cell-derived retinal pigment epithelium from patients with age-related macular degeneration exhibit reduced metabolism and matrix interactions. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31840941 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031648 }} * {{medline-title |title=Elovanoids counteract oligomeric β-amyloid-induced gene expression and protect photoreceptors. |date=26.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31712409 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883841 }} * {{medline-title |title=Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina. |date=19.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31699817 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876195 }} * {{medline-title |title=Age, lipofuscin and melanin oxidation affect fundus near-infrared autofluorescence. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31648994 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838394 }} * {{medline-title |title=Relevance of working memory for reinforcement learning in older adults varies with timescale of learning. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31544587 |full-text-url=https://sci-hub.do/10.1080/13825585.2019.1664389 }} * {{medline-title |title=Expression and Function of Mas-Related G Protein-Coupled Receptor D and Its Ligand Alamandine in Retina. |date=01.2020 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older adults with rheumatoid arthritis. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32467712 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229606 }} * {{medline-title |title=PTSD and the klotho longevity gene: Evaluation of longitudinal effects on inflammation via DNA methylation. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32438247 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293549 }} * {{medline-title |title=Bereavement is associated with reduced systemic inflammation: C-reactive protein before and after widowhood. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32283288 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415735 }} * {{medline-title |title=The Impact of Age on the Prevalence of Sarcopenic Obesity in Bariatric Surgery Candidates. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32249368 |full-text-url=https://sci-hub.do/10.1007/s11695-019-04198-4 }} * {{medline-title |title=Intake of 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spines loss, and dynamic dendritic spines changes are age-dependent in the rat. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32950615 |full-text-url=https://sci-hub.do/10.1016/j.jchemneu.2020.101858 }} * {{medline-title |title=Deregulated expression of a longevity gene, Klotho, in the C9orf72 deletion mice with impaired synaptic plasticity and adult hippocampal neurogenesis. |date=04.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32887666 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473815 }} * {{medline-title |title=COX5A Plays a Vital Role in Memory Impairment Associated With Brain Aging [i]via[/i] the BDNF/ERK1/2 Signaling Pathway. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32754029 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365906 }} * {{medline-title |title=Changes of fat-mass and obesity-associated protein expression in the hippocampus in animal models of high-fat diet-induced obesity and D-galactose-induced aging. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32647628 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336480 }} * {{medline-title |title=Phenylbutyrate ameliorates prefrontal cortex, hippocampus, and nucleus accumbens neural atrophy as well as synaptophysin and GFAP stress in aging mice. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32531811 |full-text-url=https://sci-hub.do/10.1002/syn.22177 }} * {{medline-title |title=Heterogeneity in brain distribution of activated microglia and astrocytes in a rat ischemic model of Alzheimer's disease after 2 years of survival. |date=05.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32501292 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343500 }} * {{medline-title |title=Hippocampal Subregion Transcriptomic Profiles Reflect Strategy Selection during Cognitive Aging. |date=17.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32376783 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326352 }} * {{medline-title |title=Associations between pattern separation and hippocampal subfield structure and function vary along the lifespan: A 7 T imaging study. |date=05.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32371923 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200747 }} * {{medline-title |title=Laminarin Pretreatment Provides Neuroprotection against Forebrain Ischemia/Reperfusion Injury by Reducing Oxidative Stress and Neuroinflammation in Aged Gerbils. |date=15.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32326571 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230782 }} * {{medline-title |title=Age-dependent Alteration in Mitochondrial Dynamics and Autophagy in Hippocampal Neuron of Cannabinoid CB1 Receptor-deficient Mice. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32294520 |full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2020.03.014 }} * {{medline-title |title=Functional Connectivity of Hippocampal CA3 Predicts Neurocognitive Aging via [[CA1]]-Frontal Circuit. |date=30.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32239141 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325802 }} * {{medline-title |title=Integration of qRT-PCR and Immunohistochemical Techniques for mRNA Expression and Localization of m1AChR in the Brain of Aging Rat. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32219760 |full-text-url=https://sci-hub.do/10.1007/978-1-0716-0471-7_23 }} * {{medline-title |title=Role of Eclipta prostrata extract in improving spatial learning and memory deficits in D-galactose-induced aging in rats. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32186114 }} * {{medline-title |title=Differential annualized rates of hippocampal subfields atrophy in aging and future Alzheimer's clinical syndrome. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32107063 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.01.011 }} * {{medline-title |title=Rectification of radiotherapy-induced cognitive impairments in aged mice by reconstituted Sca-1 stem cells from young donors. |date=07.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32028989 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006105 }} * {{medline-title |title=Increasing neurogenesis refines hippocampal activity rejuvenating navigational learning strategies and contextual memory throughout life. |date=09.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31919362 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952376 }} * {{medline-title |title=Memory Performance Correlates of Hippocampal Subfield Volume in Mild Cognitive Impairment Subtype. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31849620 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897308 }} * {{medline-title |title=Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses. |date=23.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31873156 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927957 }} * {{medline-title |title=Methylene blue inhibits Caspase-6 activity, and reverses Caspase-6-induced cognitive impairment and neuroinflammation in aged mice. |date=16.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31843022 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915996 }} * {{medline-title |title=Long-term Memory Upscales Volume of Postsynaptic Densities in the Process that Requires Autophosphorylation of αCaMKII. |date=14.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31800021 |full-text-url=https://sci-hub.do/10.1093/cercor/bhz261 }} * {{medline-title |title=PACAP27 mitigates an age-dependent hippocampal vulnerability to PGJ2-induced spatial learning deficits and neuroinflammation in mice. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31769222 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955932 }} * {{medline-title |title=Inhibition of oxidative stress by testosterone improves synaptic plasticity in senescence accelerated mice. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31746286 |full-text-url=https://sci-hub.do/10.1080/15287394.2019.1683988 }} * {{medline-title |title=Restored presynaptic synaptophysin and cholinergic inputs contribute to the protective effects of physical running on spatial memory in aged mice. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31470103 |full-text-url=https://sci-hub.do/10.1016/j.nbd.2019.104586 }} * {{medline-title |title=Senescent neurophysiology: Ca signaling from the membrane to the nucleus. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31394200 |full-text-url=https://sci-hub.do/10.1016/j.nlm.2019.107064 }} ==GC== * {{medline-title |title=Body Size and Cuticular Hydrocarbons as Larval Age Indicators in the Forensic Blow Fly, Chrysomya albiceps (Diptera: Calliphoridae). |date=04.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33274739 |full-text-url=https://sci-hub.do/10.1093/jme/tjaa256 }} * {{medline-title |title=Composition of peony petal fatty acids and flavonoids and their effect on Caenorhabditis elegans lifespan. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33092723 |full-text-url=https://sci-hub.do/10.1016/j.plaphy.2020.06.029 }} * {{medline-title |title=Photo aging and fragmentation of polypropylene food packaging materials in artificial seawater. |date=01.01.2021 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33039831 |full-text-url=https://sci-hub.do/10.1016/j.watres.2020.116456 }} * {{medline-title |title=Secretory galectin-3 induced by glucocorticoid stress triggers stemness exhaustion of hepatic progenitor cells. |date=04.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32989051 |full-text-url=https://sci-hub.do/10.1074/jbc.RA120.012974 }} * {{medline-title |title=Optimization of Ethanol Detection by Automatic Headspace Method for Cellulose Insulation Aging of Oil-immersed Transformers. |date=15.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32679756 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407484 }} * {{medline-title |title=Sensory, olfactometric and chemical characterization of the aroma potential of Garnacha and Tempranillo winemaking grapes. |date=30.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32569964 |full-text-url=https://sci-hub.do/10.1016/j.foodchem.2020.127207 }} * {{medline-title |title=Accelerated Cognitive Ageing in epilepsy: exploring the effective connectivity between resting-state networks and its relation to cognitive decline. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32529058 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283153 }} * {{medline-title |title=Characterization of Jinhua ham aroma profiles in specific to aging time by gas chromatography-ion mobility spectrometry ([[GC]]-IMS). |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32417671 |full-text-url=https://sci-hub.do/10.1016/j.meatsci.2020.108178 }} * {{medline-title |title=Quantitative Profiling of Lipid Species in Caenorhabditis elegans with Gas Chromatography-Mass Spectrometry. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32410029 |full-text-url=https://sci-hub.do/10.1007/978-1-0716-0592-9_10 }} * {{medline-title |title=Physicochemical characterization of a polysaccharide from Agrocybe aegirita and its anti-ageing activity. |date=15.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32172871 |full-text-url=https://sci-hub.do/10.1016/j.carbpol.2020.116056 }} * {{medline-title |title=Structural characteristics, antioxidant properties and antiaging activities of galactan produced by Mentha haplocalyx Briq. |date=15.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32070549 |full-text-url=https://sci-hub.do/10.1016/j.carbpol.2020.115936 }} * {{medline-title |title=Contribution of Volatile Odorous Terpenoid Compounds to Aged Cognac Spirits Aroma in a Context of Multicomponent Odor Mixtures. |date=25.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32052967 |full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b06656 }} * {{medline-title |title=Plasma Formate Is Greater in Fetal and Neonatal Rats Compared with Their Mothers. |date=01.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31912134 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198295 }} * {{medline-title |title=Development of a new strategy for studying the aroma potential of winemaking grapes through the accelerated hydrolysis of phenolic and aromatic fractions (PAFs). |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31882095 |full-text-url=https://sci-hub.do/10.1016/j.foodres.2019.108728 }} * {{medline-title |title=Compromised steady-state germinal center activity with age in nonhuman primates. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31840398 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996951 }} * {{medline-title |title=Endogenous Glucocorticoid Signaling in the Regulation of Bone and Marrow Adiposity: Lessons from Metabolism and Cross Talk in Other Tissues. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31749087 |full-text-url=https://sci-hub.do/10.1007/s11914-019-00554-6 }} * {{medline-title |title=4,5-Diphenyl-2-methyl picolinate induces cellular senescence by accumulating DNA damage and activating associated signaling pathways in gastric cancer. |date=01.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31639393 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116973 }} * {{medline-title |title=Relationship Between the Dose Administered, Target Tissue Dose, and Toxicity Level After Acute Oral Exposure to Bifenthrin and Tefluthrin in Young Adult Rats. |date=01.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31573616 |full-text-url=https://sci-hub.do/10.1093/toxsci/kfz204 }} * {{medline-title |title=Sugar Beet Pectin Supplementation Did Not Alter Profiles of Fecal Microbiota and Exhaled Breath in Healthy Young Adults and Healthy Elderly. |date=12.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31547291 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770243 }} * {{medline-title |title=Identification and analysis of new α- and β-hydroxy ketones related to the formation of 3-methyl-2,4-nonanedione in musts and red wines. |date=01.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31520920 |full-text-url=https://sci-hub.do/10.1016/j.foodchem.2019.125486 }} * {{medline-title |title=Neonatal T Follicular Helper Cells Are Lodged in a Pre-T Follicular Helper Stage Favoring Innate Over Adaptive Germinal Center Responses. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31456798 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700230 }} * {{medline-title |title=Identification of Dialkylpyrazines Off-Flavors in Oak Wood. |date=11.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31423769 |full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b03185 }} * {{medline-title |title=Metabolomics Coupled with Transcriptomics Approach Deciphering Age Relevance in Sepsis. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31440390 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675524 }} ==NLRP3== * {{medline-title |title=Innate and Adaptive Immunity in Aging and Longevity: The Foundation of Resilience. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33269094 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673842 }} * {{medline-title |title=TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity. |date=27.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33113366 |full-text-url=https://sci-hub.do/10.1016/j.celrep.2020.108326 }} * {{medline-title |title=Repeated propofol exposure-induced neuronal damage and cognitive impairment in aged rats by activation of NF-κB pathway and [[NLRP3]] inflammasome. |date=01.01.2021 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33115643 |full-text-url=https://sci-hub.do/10.1016/j.neulet.2020.135461 }} * {{medline-title |title=A Small Molecule Stabilizer of the MYC G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma. |date=13.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066043 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650714 }} * {{medline-title |title=Interleukin-1β Drives Cellular Senescence of Rat Astrocytes Induced by Oligomerized Amyloid β Peptide and Oxidative Stress. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013631 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493674 }} * {{medline-title |title=Mechanisms of [[NLRP3]] priming in inflammaging and age related diseases. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32883606 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571497 }} * {{medline-title |title=Lamivudine Inhibits [i]Alu[/i] RNA-induced Retinal Pigment Epithelium Degeneration via Anti-inflammatory and Anti-senescence Activities. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32855848 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422901 }} * {{medline-title |title=The [[NLRP3]] Inflammasome: Metabolic Regulation and Contribution to Inflammaging. |date=30.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32751530 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463618 }} * {{medline-title |title=Aging aggravated liver ischemia and reperfusion injury by promoting STING-mediated [[NLRP3]] activation in macrophages. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32666684 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431827 }} * {{medline-title |title=Targeting [[NLRP3]] Inflammasome Reduces Age-Related Experimental Alveolar Bone Loss. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32531176 |full-text-url=https://sci-hub.do/10.1177/0022034520933533 }} * {{medline-title |title=Korean Red Ginseng Suppresses the Expression of Oxidative Stress Response and [[NLRP3]] Inflammasome Genes in Aged C57BL/6 Mouse Ovaries. |date=22.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32331214 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231237 }} * {{medline-title |title=Cepharanthine promotes the effect of dexmedetomidine on the deposition of β-amyloid in the old age of the senile dementia rat model by regulating inflammasome expression. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32337948 |full-text-url=https://sci-hub.do/10.5114/fn.2019.89855 }} * {{medline-title |title=Ginsenoside Rg1 ameliorates glomerular fibrosis during kidney aging by inhibiting NOX4 and [[NLRP3]] inflammasome activation in SAMP8 mice. |date=27.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32114413 |full-text-url=https://sci-hub.do/10.1016/j.intimp.2020.106339 }} * {{medline-title |title=Blockade of the [[NLRP3]] inflammasome improves metabolic health and lifespan in obese mice. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31975052 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206474 }} * {{medline-title |title=Autophagy and [[NLRP3]] inflammasome crosstalk in neuroinflammation in aged bovine brains. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31903559 |full-text-url=https://sci-hub.do/10.1002/jcp.29426 }} * {{medline-title |title=[[NLRP3]] Inflammasome Inhibition by MCC950 in Aged Mice Improves Health via Enhanced Autophagy and PPARα Activity. |date=13.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31603987 |full-text-url=https://sci-hub.do/10.1093/gerona/glz239 }} * {{medline-title |title=[[NLRP3]] inflammasome suppression improves longevity and prevents cardiac aging in male mice. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31625260 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974709 }} * {{medline-title |title=Reduced NRF2 expression suppresses endothelial progenitor cell function and induces senescence during aging. |date=08.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31494646 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756903 }} * {{medline-title |title=Effect of Aging on Taurine Transporter (TauT) Expression in the Mouse Brain Cortex. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31468381 |full-text-url=https://sci-hub.do/10.1007/978-981-13-8023-5_1 }} ==SCD== * {{medline-title |title=Cognitive training and brain stimulation in prodromal Alzheimer's disease (AD-Stim)-study protocol for a double-blind randomized controlled phase IIb (monocenter) trial. |date=07.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33160420 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648990 }} * {{medline-title |title=Blood Pressure in Different Dementia Disorders, Mild Cognitive Impairment, and Subjective Cognitive Decline. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33110409 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488384 }} * {{medline-title |title=Known-Groups and Convergent Validity of the Telephone Rey Auditory Verbal Learning Test total Learning Scores for Distinguishing Between Older Adults With Amnestic Cognitive Impairment and Subjective Cognitive Decline. |date=17.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33067996 |full-text-url=https://sci-hub.do/10.1093/arclin/acaa085 }} * {{medline-title |title=Subjective cognitive decline as a predictor of future cognitive decline: a systematic review. |date=07-09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32973979 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500809 }} * {{medline-title |title=Geriatric assessment for older adults with sickle cell disease: protocol for a prospective cohort pilot study. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32974042 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495855 }} * {{medline-title |title=Prevalence and psychosocial correlates of subjectively perceived decline in five cognitive domains: Results from a population-based cohort study in Germany. |date=08.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32510658 |full-text-url=https://sci-hub.do/10.1002/gps.5359 }} * {{medline-title |title=SC411 treatment can enhance survival in a mouse model of sickle cell disease. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32447175 |full-text-url=https://sci-hub.do/10.1016/j.plefa.2020.102110 }} * {{medline-title |title=DNA fragmentation of human spermatozoa: Simple assessment of single- and double-strand DNA breaks and their respective dynamic behavioral response. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32416007 |full-text-url=https://sci-hub.do/10.1111/andr.12819 }} * {{medline-title |title=Psychometric Cognitive Decline Precedes the Advent of Subjective Cognitive Decline in the Evolution of Alzheimer's Disease. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32388509 |full-text-url=https://sci-hub.do/10.1159/000507286 }} * {{medline-title |title=Serum alkaline phosphatase is elevated and inversely correlated with cognitive functions in subjective cognitive decline: results from the ReGAl 2.0 project. |date=03.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32363431 |full-text-url=https://sci-hub.do/10.1007/s40520-020-01572-6 }} * {{medline-title |title=Changes in Activity Participation Among Older Adults With Subjective Cognitive Decline or Objective Cognitive Deficits. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32010049 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974583 }} * {{medline-title |title=Age, gender and drug therapy influences on Tpeak-tend interval and on electrical risk score. |date=03-04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32023499 |full-text-url=https://sci-hub.do/10.1016/j.jelectrocard.2020.01.009 }} * {{medline-title |title=Comorbid Chronic Conditions Among Older Adults with Subjective Cognitive Decline, United States, 2015-2017. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31915725 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938465 }} * {{medline-title |title=Resting State BOLD Variability Is Linked to White Matter Vascular Burden in Healthy Aging but Not in Older Adults With Subjective Cognitive Decline. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31920589 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936515 }} * {{medline-title |title=Estimated Life Expectancy and Income of Patients With Sickle Cell Disease Compared With Those Without Sickle Cell Disease. |date=01.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31730182 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902797 }} * {{medline-title |title=Does Empirically Derived Classification of Individuals with Subjective Cognitive Complaints Predict Dementia? |date=07.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31703450 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895967 }} * {{medline-title |title=Spatiotemporal Oscillatory Patterns During Working Memory Maintenance in Mild Cognitive Impairment and Subjective Cognitive Decline. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31522594 |full-text-url=https://sci-hub.do/10.1142/S0129065719500199 }} * {{medline-title |title=Microstructural Correlates and Laterality Effect of Prospective Memory in Non-Demented Adults with Memory Complaints. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31466053 |full-text-url=https://sci-hub.do/10.1159/000501366 }} ==BDNF== * {{medline-title |title=Influence of [i][[BDNF]][/i] Genetic Polymorphisms in the Pathophysiology of Aging-related Diseases. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33269104 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673859 }} * {{medline-title |title=Moderators of the Impact of (Poly)Phenols Interventions on Psychomotor Functions and [[BDNF]]: Insights from Subgroup Analysis and Meta-Regression. |date=19.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32961777 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551086 }} * {{medline-title |title=Astroglia-Derived [[BDNF]] and MSK-1 Mediate Experience- and Diet-Dependent Synaptic Plasticity. |date=18.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32708382 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407492 }} * {{medline-title |title=[[BDNF]] reverses aging-related microglial activation. |date=14.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32664974 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362451 }} * {{medline-title |title=High Supervised Resistance Training in Elderly Women: The Role of Supervision Ratio. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32509119 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241618 }} * {{medline-title |title=Metformin regulates astrocyte reactivity in Parkinson's disease and normal aging. |date=15.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32497590 |full-text-url=https://sci-hub.do/10.1016/j.neuropharm.2020.108173 }} * {{medline-title |title=Aging-Induced Brain-Derived Neurotrophic Factor in Adipocyte Progenitors Contributes to Adipose Tissue Dysfunction. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32489703 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220283 }} * {{medline-title |title=The Role of [[BDNF]] on Aging-Modulation Markers. |date=09.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32397504 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287884 }} * {{medline-title |title=Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice. |date=08.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32268299 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185103 }} * {{medline-title |title=Microglia senescence occurs in both substantia nigra and ventral tegmental area. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32275335 |full-text-url=https://sci-hub.do/10.1002/glia.23834 }} * {{medline-title |title=Towards an understanding of the physical activity-[[BDNF]]-cognition triumvirate: A review of associations and dosage. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32171785 |full-text-url=https://sci-hub.do/10.1016/j.arr.2020.101044 }} * {{medline-title |title=Impact of [[BDNF]] and sex on maintaining intact memory function in early midlife. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31948671 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.12.014 }} * {{medline-title |title=Testosterone replacement causes dose-dependent improvements in spatial memory among aged male rats. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31901624 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080566 }} * {{medline-title |title=The effects of aerobic exercise intensity on memory in older adults. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31665610 |full-text-url=https://sci-hub.do/10.1139/apnm-2019-0495 }} * {{medline-title |title=Protective effects of vitamin D on neurophysiologic alterations in brain aging: role of brain-derived neurotrophic factor ([[BDNF]]). |date=16.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31524100 |full-text-url=https://sci-hub.do/10.1080/1028415X.2019.1665854 }} * {{medline-title |title=Differential Effects of Physical Exercise, Cognitive Training, and Mindfulness Practice on Serum [[BDNF]] Levels in Healthy Older Adults: A Randomized Controlled Intervention Study. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31498125 |full-text-url=https://sci-hub.do/10.3233/JAD-190756 }} * {{medline-title |title=Dietary Supplementation with Fish Oil or Conjugated Linoleic Acid Relieves Depression Markers in Mice by Modulation of the Nrf2 Pathway. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31398773 |full-text-url=https://sci-hub.do/10.1002/mnfr.201900243 }} ==TERT== * {{medline-title |title=Telomeres and telomerase in risk assessment of cardiovascular diseases. |date=15.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33171154 |full-text-url=https://sci-hub.do/10.1016/j.yexcr.2020.112361 }} * {{medline-title |title=A 4-Base-Pair Core-Enclosing Helix in Telomerase RNA Is Essential for Activity and for Binding to the Telomerase Reverse Transcriptase Catalytic Protein Subunit. |date=20.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33046533 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685517 }} * {{medline-title |title=Angiotensin inhibition and cellular senescence in the developing rat kidney. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33010296 |full-text-url=https://sci-hub.do/10.1016/j.yexmp.2020.104551 }} * {{medline-title |title=Decreased expression of [[TERT]] and telomeric proteins as human ovaries age may cause telomere shortening. |date=27.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32856217 |full-text-url=https://sci-hub.do/10.1007/s10815-020-01932-1 }} * {{medline-title |title=The secrets of telomerase: Retrospective analysis and future prospects. |date=15.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32698073 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118115 }} * {{medline-title |title=Gene expression in human mesenchymal stem cell aging cultures: modulation by short peptides. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32399807 |full-text-url=https://sci-hub.do/10.1007/s11033-020-05506-3 }} * {{medline-title |title=Unravelling Cellular Mechanisms of Stem Cell Senescence: An Aid from Natural Bioactive Molecules. |date=20.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32244882 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150900 }} * {{medline-title |title=Expression of telomerase reverse transcriptase positively correlates with duration of lithium treatment in bipolar disorder. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32114208 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334059 }} * {{medline-title |title=FAM96B inhibits the senescence of dental pulp stem cells. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32039527 |full-text-url=https://sci-hub.do/10.1002/cbin.11319 }} * {{medline-title |title=Aging and biomarkers: Transcriptional levels evaluation of Osteopontin/miRNA-181a axis in hepatic tissue of rats in different age ranges. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32061643 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110879 }} * {{medline-title |title=Resveratrol inhibits adipocyte differentiation and cellular senescence of human bone marrow stromal stem cells. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31978617 |full-text-url=https://sci-hub.do/10.1016/j.bone.2020.115252 }} * {{medline-title |title=Characterization of human telomerase reverse transcriptase immortalized anterior cruciate ligament cell lines. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31948601 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962762 }} * {{medline-title |title=Mitochondria, Telomeres and Telomerase Subunits. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31781563 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851022 }} * {{medline-title |title=Towards Therapeutic Alternatives for Mercury Neurotoxicity in the Amazon: Unraveling the Pre-Clinical Effects of the Superfruit Açaí ([i]Euterpe oleracea[/i], Mart.) as Juice for Human Consumption. |date=26.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31717801 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893510 }} * {{medline-title |title=Replication Stress at Telomeric and Mitochondrial DNA: Common Origins and Consequences on Ageing. |date=08.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31597307 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801922 }} * {{medline-title |title=Telomerase Biology Associations Offer Keys to Cancer and Aging Therapeutics. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31544708 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403649 }} * {{medline-title |title=Transient induction of telomerase expression mediates senescence and reduces tumorigenesis in primary fibroblasts. |date=17.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31481614 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754593 }} ==PGC== * {{medline-title |title=The Aging Stress Response and Its Implication for AMD Pathogenesis. |date=22.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33266495 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700335 }} * {{medline-title |title=Constitutive [[PGC]]-1α Overexpression in Skeletal Muscle Does Not Contribute to Exercise-Induced Neurogenesis. |date=16.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33200398 |full-text-url=https://sci-hub.do/10.1007/s12035-020-02189-6 }} * {{medline-title |title=Dysregulated Autophagy Mediates Sarcopenic Obesity and Its Complications via AMPK and [[PGC]]1α Signaling Pathways: Potential Involvement of Gut Dysbiosis as a Pathological Link. |date=19.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32961822 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555990 }} * {{medline-title |title=Resemblance and differences in dietary restriction nephroprotective mechanisms in young and old rats. |date=24.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32970613 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585108 }} * {{medline-title |title=Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32748504 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399374 }} * {{medline-title |title=[[PGC]]-1α-mediated regulation of mitochondrial function and physiological implications. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32516539 |full-text-url=https://sci-hub.do/10.1139/apnm-2020-0005 }} * {{medline-title |title=Targeting Mitochondrial Network Architecture in Down Syndrome and Aging. |date=29.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32365535 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247689 }} * {{medline-title |title=Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in an age-specific manner. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32372536 |full-text-url=https://sci-hub.do/10.1096/fj.201903113RR }} * {{medline-title |title=A novel dipeptide from potato protein hydrolysate augments the effects of exercise training against high-fat diet-induced damages in senescence-accelerated mouse-prone 8 by boosting pAMPK / SIRT1/ [[PGC]]-1α/ pFOXO3 pathway. |date=26.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32335547 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202530 }} * {{medline-title |title=Mitochondrial nucleoid remodeling and biogenesis are regulated by the p53-p21 -PKCζ pathway in p16 -silenced cells. |date=24.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32330121 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202532 }} * {{medline-title |title=[Metabolic Alteration in Aging Process: Metabolic Remodeling in White Adipose Tissue by Caloric Restriction]. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32115557 |full-text-url=https://sci-hub.do/10.1248/yakushi.19-00193-2 }} * {{medline-title |title=Kynurenine aminotransferase isoforms display fiber-type specific expression in young and old human skeletal muscle. |date=15.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32068089 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110880 }} * {{medline-title |title=Ubiquinol-10 delays postovulatory oocyte aging by improving mitochondrial renewal in pigs. |date=20.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31958774 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053629 }} * {{medline-title |title=Mitochondrial oxidative capacity and NAD biosynthesis are reduced in human sarcopenia across ethnicities. |date=20.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31862890 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925228 }} * {{medline-title |title=MicroRNA-34a (miR-34a) Mediates Retinal Endothelial Cell Premature Senescence through Mitochondrial Dysfunction and Loss of Antioxidant Activities. |date=22.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31443378 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769710 }} * {{medline-title |title=Constitutive [[PGC]]-1α overexpression in skeletal muscle does not protect from age-dependent decline in neurogenesis. |date=23.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31444397 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707251 }} ==CD28== * {{medline-title |title=Premature CD4 T Cells Senescence Induced by Chronic Infection in Patients with Acute Coronary Syndrome. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33269101 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673853 }} * {{medline-title |title=The IMMENSE Study: The Interplay Between iMMune and ENdothelial Cells in Mediating Cardiovascular Risk in Systemic Lupus Erythematosus. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33193356 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658008 }} * {{medline-title |title=Emergence of T cell immunosenescence in diabetic chronic kidney disease. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33088331 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574244 }} * {{medline-title |title=The relationship between Chlamydia pneumoniae infection and CD4/CD8 ratio, lymphocyte subsets in middle-aged and elderly individuals. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33068732 |full-text-url=https://sci-hub.do/10.1016/j.micpath.2020.104541 }} * {{medline-title |title=Next steps in mechanisms of inflammaging. |date=22.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32960694 |full-text-url=https://sci-hub.do/10.1080/15548627.2020.1822089 }} * {{medline-title |title=A randomized pilot trial to evaluate the benefit of the concomitant use of atorvastatin and Raltegravir on immunological markers in protease-inhibitor-treated subjects living with HIV. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32941476 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498036 }} * {{medline-title |title=Aging affects responsiveness of peripheral blood mononuclear cells to immunosuppression of periodontal ligament stem cells. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32663414 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364836 }} * {{medline-title |title=Comparison of Donepezil, Memantine, Melatonin, and Liuwei Dihuang Decoction on Behavioral and Immune Endocrine Responses of Aged Senescence-Accelerated Mouse Resistant 1 Mice. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32477103 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241684 }} * {{medline-title |title=Immunosenescent characteristics of T cells in young patients following haploidentical haematopoietic stem cell transplantation from parental donors. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32280463 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142179 }} * {{medline-title |title=Diagnosis-independent loss of T-cell costimulatory molecules in individuals with cytomegalovirus infection. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32209361 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594105 }} * {{medline-title |title=Accelerated immunosenescence in rheumatoid arthritis: impact on clinical progression. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32190092 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068869 }} * {{medline-title |title=Accelerated immune aging was correlated with lupus-associated brain fog in reproductive-age systemic lupus erythematosus patients. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32107852 |full-text-url=https://sci-hub.do/10.1111/1756-185X.13816 }} * {{medline-title |title=T cells, aging and senescence. |date=22.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32092501 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110887 }} * {{medline-title |title=Liver fibrosis and accelerated immune dysfunction (immunosenescence) among HIV-infected Russians with heavy alcohol consumption - an observational cross-sectional study. |date=31.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31892306 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938606 }} * {{medline-title |title=Effect of Allogenic Bone Marrow Mesenchymal Stem Cell Transplantation on T Cells of Old Mice. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31895587 |full-text-url=https://sci-hub.do/10.1089/cell.2019.0055 }} * {{medline-title |title=Peripheral antibody concentrations are associated with highly differentiated T cells and inflammatory processes in the human bone marrow. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31462901 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706884 }} ==HGS== * {{medline-title |title=Handgrip strength asymmetry is associated with future falls in older Americans. |date=27.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33247424 |full-text-url=https://sci-hub.do/10.1007/s40520-020-01757-z }} * {{medline-title |title=Examining Additional Aspects of Muscle Function with a Digital Handgrip Dynamometer and Accelerometer in Older Adults: A Pilot Study. |date=31.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33142897 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709634 }} * {{medline-title |title=The Relationship between Muscular Strength and Depression in Older Adults with Chronic Disease Comorbidity. |date=18.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32962093 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558624 }} * {{medline-title |title=Handgrip Strength in the Korean Population: Normative Data and Cutoff Values. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32743310 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370763 }} * {{medline-title |title=Handgrip Strength Asymmetry and Weakness Are Associated with Lower Cognitive Function: A Panel Study. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32473060 |full-text-url=https://sci-hub.do/10.1111/jgs.16556 }} * {{medline-title |title=Handgrip Strength Asymmetry and Weakness are Differentially Associated with Functional Limitations in Older Americans. |date=06.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32384713 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246814 }} * {{medline-title |title=Absolute and Body Mass Index Normalized Handgrip Strength Percentiles by Gender, Ethnicity, and Hand Dominance in Americans. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31930203 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954001 }} * {{medline-title |title=Hand grip strength variability during serial testing as an entropic biomarker of aging: a Poincaré plot analysis. |date=13.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31931730 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958685 }} * {{medline-title |title=Physical Activity and Fitness in White- and Blue-Collar Retired Men. |date=11-12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31849269 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920597 }} * {{medline-title |title=Association between Hand Grip Strength and Self-Rated Health in Middle- and Old-Aged Korean Citizens. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31842533 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987025 }} * {{medline-title |title=Weakness May Have a Causal Association With Early Mortality in Older Americans: A Matched Cohort Analysis. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31786197 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186143 }} * {{medline-title |title=Associations Between Dietary Patterns and Handgrip Strength: The Korea National Health and Nutrition Examination Survey 2014-2016. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31743070 |full-text-url=https://sci-hub.do/10.1080/07315724.2019.1691955 }} * {{medline-title |title=Effect of relative handgrip strength on cardiovascular disease among Korean adults aged 45 years and older: Results from the Korean Longitudinal Study of Aging (2006-2016). |date=01-02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31574451 |full-text-url=https://sci-hub.do/10.1016/j.archger.2019.103937 }} * {{medline-title |title=Weakness and cognitive impairment are independently and jointly associated with functional decline in aging Americans. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31520335 |full-text-url=https://sci-hub.do/10.1007/s40520-019-01351-y }} * {{medline-title |title=Association of phase angle with sarcopenia and its components in physically active older women. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31463928 |full-text-url=https://sci-hub.do/10.1007/s40520-019-01325-0 }} ==CS== * {{medline-title |title=Acute effect of bodyweight-based strength training on blood pressure of hypertensive older adults: A randomized crossover clinical trial. |date=16.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33198514 |full-text-url=https://sci-hub.do/10.1080/10641963.2020.1847130 }} * {{medline-title |title=Particle growth with photochemical age from new particle formation to haze in the winter of Beijing, China. |date=20.01.2021 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33207435 |full-text-url=https://sci-hub.do/10.1016/j.scitotenv.2020.142207 }} * {{medline-title |title=Effect of aging on stabilization of Cd and Ni by biochars and enzyme activities in a historically contaminated alkaline agricultural soil simulated with wet-dry and freeze-thaw cycling. |date=27.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143976 |full-text-url=https://sci-hub.do/10.1016/j.envpol.2020.115846 }} * {{medline-title |title=Cockayne syndrome proteins [[CS]]A and [[CS]]B maintain mitochondrial homeostasis through NAD signaling. |date=09.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33166073 |full-text-url=https://sci-hub.do/10.1111/acel.13268 }} * {{medline-title |title=Vision Impairment and Participation in Cognitively Stimulating Activities: The Health ABC Study. |date=25.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32710546 |full-text-url=https://sci-hub.do/10.1093/gerona/glaa184 }} * {{medline-title |title=Suspension training vs. traditional resistance training: effects on muscle mass, strength and functional performance in older adults. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32700098 |full-text-url=https://sci-hub.do/10.1007/s00421-020-04446-x }} * {{medline-title |title=Generational Differences in the 10-year Incidence of Impaired Contrast Sensitivity. |date=21.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32693658 |full-text-url=https://sci-hub.do/10.1080/09286586.2020.1791909 }} * {{medline-title |title=Inducible aging in Hydra oligactis implicates sexual reproduction, loss of stem cells, and genome maintenance as major pathways. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32578072 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394996 }} * {{medline-title |title=Noradrenergic Responsiveness Supports Selective Attention across the Adult Lifespan. |date=27.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32317388 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252473 }} * {{medline-title |title=Cellular senescence: from anti-cancer weapon to anti-aging target. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32060861 |full-text-url=https://sci-hub.do/10.1007/s11427-019-1629-6 }} * {{medline-title |title=Extra-mitochondrial citrate synthase initiates calcium oscillation and suppresses age-dependent sperm dysfunction. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31857692 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096335 }} * {{medline-title |title=Pathogenesis of chronic obstructive pulmonary disease (COPD) induced by cigarette smoke. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31737341 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831915 }} * {{medline-title |title=Possible Role of Amyloid Cross-Seeding in Evolvability and Neurodegenerative Disease. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31524179 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839461 }} * {{medline-title |title=Targeting p16-induced senescence prevents cigarette smoke-induced emphysema by promoting IGF1/Akt1 signaling in mice. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31428695 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689060 }} ==ACE2== * {{medline-title |title=How Does SARS-CoV-2 Affect the Central Nervous System? A Working Hypothesis. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33304284 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701095 }} * {{medline-title |title=Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33112891 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592753 }} * {{medline-title |title=A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32854108 |full-text-url=https://sci-hub.do/10.1038/s41586-020-2708-8 }} * {{medline-title |title=COVID-19 and Senotherapeutics: Any Role for the Naturally-occurring Dipeptide Carnosine? |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32765939 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390525 }} * {{medline-title |title=The dual impact of [[ACE2]] in COVID-19 and ironical actions in geriatrics and pediatrics with possible therapeutic solutions. |date=15.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32653522 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347488 }} * {{medline-title |title=The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of "inflame-aging". |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32529477 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289226 }} * {{medline-title |title=Decoding SARS-CoV-2 hijacking of host mitochondria in COVID-19 pathogenesis. |date=01.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32510973 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381712 }} * {{medline-title |title=A Mouse Model of SARS-CoV-2 Infection and Pathogenesis. |date=08.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32485164 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250783 }} * {{medline-title |title=COVID-19-associated cardiovascular morbidity in older adults: a position paper from the Italian Society of Cardiovascular Researches. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32430627 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237344 }} * {{medline-title |title=Gut microbiota and Covid-19- possible link and implications. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32430279 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217790 }} * {{medline-title |title=Inflamm-aging: Why older men are the most susceptible to SARS-CoV-2 complicated outcomes. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32389499 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252014 }} * {{medline-title |title=Restoration of the Renin-Angiotensin System Balance Is a Part of the Effect of Fasting on Cardiovascular Rejuvenation: Role of Age and Fasting Models. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31571520 |full-text-url=https://sci-hub.do/10.1089/rej.2019.2254 }} * {{medline-title |title=Angiotensin 1-7 alleviates aging-associated muscle weakness and bone loss, but is not associated with accelerated aging in [[ACE2]]-knockout mice. |date=30.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31519791 |full-text-url=https://sci-hub.do/10.1042/CS20190573 }} ==STAT3== * {{medline-title |title=Dietary Restriction Suppresses Steatosis-Associated Hepatic Tumorigenesis in Hepatitis C Virus Core Gene Transgenic Mice. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33083279 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548900 }} * {{medline-title |title=Skeletal glucocorticoid signalling determines leptin resistance and obesity in aging mice. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33045434 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596342 }} * {{medline-title |title=AMPK alleviates oxidative stress‑induced premature senescence via inhibition of NF-κB/[[STAT3]] axis-mediated positive feedback loop. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32882228 |full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111347 }} * {{medline-title |title=Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through [[STAT3]] activation. |date=08.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32848054 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486730 }} * {{medline-title |title=Cell Death by Gallotannin Is Associated with Inhibition of the JAK/STAT Pathway in Human Colon Cancer Cells. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32714471 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378856 }} * {{medline-title |title=The effect of interleukin 6 deficiency on myocardial signal transduction pathways activation induced by bacterial lipopolysaccharide in young and old mice. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32693349 |full-text-url=https://sci-hub.do/10.1016/j.advms.2020.06.006 }} * {{medline-title |title=Silibinin and SARS-CoV-2: Dual Targeting of Host Cytokine Storm and Virus Replication Machinery for Clinical Management of COVID-19 Patients. |date=07.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32517353 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356916 }} * {{medline-title |title=Implication of JAK1/[[STAT3]]/SOCS3 Pathway in Aging of Cerebellum of Male Rat: Histological and Molecular study. |date=01.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32483368 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264275 }} * {{medline-title |title=Atorvastatin-induced senescence of hepatocellular carcinoma is mediated by downregulation of hTERT through the suppression of the IL-6/[[STAT3]] pathway. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32257389 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105491 }} * {{medline-title |title=Deciphering the Molecular Mechanism of Spontaneous Senescence in Primary Epithelial Ovarian Cancer Cells. |date=27.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32012719 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072138 }} * {{medline-title |title=Persistent Activation of [[STAT3]] Pathway in the Retina Induced Vision Impairment and Retinal Degenerative Changes in Ageing Mice. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31884637 |full-text-url=https://sci-hub.do/10.1007/978-3-030-27378-1_58 }} * {{medline-title |title=Interleukin-10 induces senescence of activated hepatic stellate cells via [[STAT3]]-p53 pathway to attenuate liver fibrosis. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31730896 |full-text-url=https://sci-hub.do/10.1016/j.cellsig.2019.109445 }} ==CP== * {{medline-title |title=A Life Course Perspective on Growing Older With Cerebral Palsy. |date=19.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33213304 |full-text-url=https://sci-hub.do/10.1177/1049732320971247 }} * {{medline-title |title=The molecular anatomy and functions of the choroid plexus in healthy and diseased brain. |date=01.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32750317 |full-text-url=https://sci-hub.do/10.1016/j.bbamem.2020.183430 }} * {{medline-title |title=The effects and mechanism of collagen peptide and elastin peptide on skin aging induced by D-galactose combined with ultraviolet radiation. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32717457 |full-text-url=https://sci-hub.do/10.1016/j.jphotobiol.2020.111964 }} * {{medline-title |title=Model based strategies towards protein A resin lifetime optimization and supervision. |date=16.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32709318 |full-text-url=https://sci-hub.do/10.1016/j.chroma.2020.461261 }} * {{medline-title |title=The influence of age and environmental conditions on supplement intake by beef cattle winter grazing northern mixed-grass rangelands. |date=01.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32658282 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455287 }} * {{medline-title |title=Cyclophosphamide, a cancer chemotherapy drug-induced early onset of reproductive senescence and alterations in reproductive performance and their prevention in mice. |date=15.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32536211 |full-text-url=https://sci-hub.do/10.1080/01480545.2020.1774773 }} * {{medline-title |title=Asymptomatic [i]Clostridium perfringens[/i] Inhabitation in Intestine Can Cause Inflammation, Apoptosis, and Disorders in Brain. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31928429 |full-text-url=https://sci-hub.do/10.1089/fpd.2019.2677 }} * {{medline-title |title=The Role of the Clinical Pharmacist in the Management of People Living with HIV in the Modern Antiretroviral Era. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31834321 |full-text-url=https://sci-hub.do/10.24875/AIDSRev.19000089 }} * {{medline-title |title=A clinically feasible method for the assessment and characterization of pain in patients with chronic pancreatitis. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31787527 |full-text-url=https://sci-hub.do/10.1016/j.pan.2019.11.007 }} * {{medline-title |title=Differences in geometric strength at the contralateral hip between men with hip fracture and non-fractured comparators. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31812699 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037571 }} * {{medline-title |title=Factors associated with the number of clinical pharmacy recommendations: findings from an observational study in geriatric inpatients. |date=23.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31642397 |full-text-url=https://sci-hub.do/10.1080/17843286.2019.1683128 }} * {{medline-title |title=Protection against oxidative stress and anti-aging effect in Drosophila of royal jelly-collagen peptide. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31622731 |full-text-url=https://sci-hub.do/10.1016/j.fct.2019.110881 }} ==APP== * {{medline-title |title=Pre-symptomatic Caspase-1 inhibitor delays cognitive decline in a mouse model of Alzheimer disease and aging. |date=11.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32917871 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486940 }} * {{medline-title |title=Regorafenib Regulates AD Pathology, Neuroinflammation, and Dendritic Spinogenesis in Cells and a Mouse Model of AD. |date=09.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32660121 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408082 }} * {{medline-title |title=An agnostic reevaluation of the amyloid cascade hypothesis of Alzheimer's disease pathogenesis: The role of [[APP]] homeostasis. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32588983 |full-text-url=https://sci-hub.do/10.1002/alz.12124 }} * {{medline-title |title=Transcriptomic profiling of microglia and astrocytes throughout aging. |date=01.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32238175 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115095 }} * {{medline-title |title=Platelets in Amyloidogenic Mice Are Activated and Invade the Brain. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32194368 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063083 }} * {{medline-title |title=CHIP modulates [[APP]]-induced autophagy-dependent pathological symptoms in Drosophila. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31777182 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996943 }} * {{medline-title |title=Studies on [[APP]] metabolism related to age-associated mitochondrial dysfunction in [[APP]]/PS1 transgenic mice. |date=19.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31744937 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914425 }} * {{medline-title |title=Intermittent Hypoxia-Hyperoxia Training Improves Cognitive Function and Decreases Circulating Biomarkers of Alzheimer's Disease in Patients with Mild Cognitive Impairment: A Pilot Study. |date=30.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31671598 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862463 }} * {{medline-title |title=The Implication of Androgens in the Presence of Protein Kinase C to Repair Alzheimer’s Disease-Induced Cognitive Dysfunction |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31677609 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984714 }} * {{medline-title |title=Modulation of Neural and Muscular Adaptation Processes During Resistance Training by Fish Protein Ingestions in Older Adults. |date=17.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31596471 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164534 }} * {{medline-title |title=Antipsychotic Polypharmacy in Older Adult Asian Patients With Schizophrenia: Research on Asian Psychotropic Prescription Pattern. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31480982 |full-text-url=https://sci-hub.do/10.1177/0891988719862636 }} * {{medline-title |title=A pleiotropic role for exosomes loaded with the amyloid β precursor protein carboxyl-terminal fragments in the brain of Down syndrome patients. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31479861 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960325 }} ==ATM== * {{medline-title |title=S[[ATM]]F Suppresses the Premature Senescence Phenotype of the [[ATM]] Loss-of-Function Mutant and Improves Its Fertility in [i]Arabidopsis[/i]. |date=30.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143308 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662627 }} * {{medline-title |title=[[ATM]] mediated-p53 signaling pathway forms a novel axis for senescence control. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32949791 |full-text-url=https://sci-hub.do/10.1016/j.mito.2020.09.002 }} * {{medline-title |title=Non-canonical [[ATM]]/MRN activities temporally define the senescence secretory program. |date=05.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32785991 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534619 }} * {{medline-title |title=[[ATM]] is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging. |date=22.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32201398 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138542 }} * {{medline-title |title=[[ATM]] suppresses leaf senescence triggered by DNA double-strand break through epigenetic control of senescence-associated genes in Arabidopsis. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32163596 |full-text-url=https://sci-hub.do/10.1111/nph.16535 }} * {{medline-title |title=Glioblastoma Cells Do Not Affect Axitinib-Dependent Senescence of HUVECs in a Transwell Coculture Model. |date=21.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32098270 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073100 }} * {{medline-title |title=Declining BRCA-Mediated DNA Repair in Sperm Aging and its Prevention by Sphingosine-1-Phosphate. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31916095 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065969 }} * {{medline-title |title=BRCA-related [[ATM]]-mediated DNA double-strand break repair and ovarian aging. |date=01.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31822904 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935693 }} * {{medline-title |title=[[ATM]] Deficiency Accelerates DNA Damage, Telomere Erosion, and Premature T Cell Aging in HIV-Infected Individuals on Antiretroviral Therapy. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31781094 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856652 }} * {{medline-title |title=SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31565865 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850945 }} * {{medline-title |title=LncRNA RP11-670E13.6, interacted with hnRNPH, delays cellular senescence by sponging microRNA-663a in UVB damaged dermal fibroblasts. |date=23.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31444317 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738423 }} * {{medline-title |title=Tel1/[[ATM]] Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31391264 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781906 }} ==GFAP== * {{medline-title |title=Immunohistological Detection of Active Satellite Cellsin Rat Dorsal Root Ganglia after Parenteral Administration of Lipopolysaccharide and during Aging. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32990851 |full-text-url=https://sci-hub.do/10.1007/s10517-020-04950-2 }} * {{medline-title |title=Transgenic Mice Expressing Human α-Synuclein in Noradrenergic Neurons Develop Locus Ceruleus Pathology and Nonmotor Features of Parkinson's Disease. |date=23.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32868457 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511194 }} * {{medline-title |title=ApoE Genotype-Dependent Response to Antioxidant and Exercise Interventions on Brain Function. |date=25.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32630431 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346214 }} * {{medline-title |title=Age-Dependent Heterogeneity of Murine Olfactory Bulb Astrocytes. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32581775 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296154 }} * {{medline-title |title=Neuroinflammation in Aged Brain: Impact of the Oral Administration of Ellagic Acid Microdispersion. |date=21.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32455600 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279224 }} * {{medline-title |title=Long-term treatment with spermidine increases health span of middle-aged Sprague-Dawley male rats. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32285289 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287009 }} * {{medline-title |title=Meta-analysis of human prefrontal cortex reveals activation of [[GFAP]] and decline of synaptic transmission in the aging brain. |date=05.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32138778 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059712 }} * {{medline-title |title=Astroglial biotin deprivation under endoplasmic reticulum stress uncouples BCAA-mTORC1 role in lipid synthesis to prolong autophagy inhibition in the aging brain. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32030764 |full-text-url=https://sci-hub.do/10.1111/jnc.14979 }} * {{medline-title |title=Long-lived mice with reduced growth hormone signaling have a constitutive upregulation of hepatic chaperone-mediated autophagy. |date=12.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32013718 |full-text-url=https://sci-hub.do/10.1080/15548627.2020.1725378 }} * {{medline-title |title=Lipopolysaccharide exposure during late embryogenesis triggers and drives Alzheimer-like behavioral and neuropathological changes in CD-1 mice. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31997558 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066339 }} * {{medline-title |title=Increased levels of Aβ42 decrease the lifespan of ob/ob mice with dysregulation of microglia and astrocytes. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31907998 |full-text-url=https://sci-hub.do/10.1096/fj.201901028RR }} * {{medline-title |title=Selective brain neuronal and glial losses without changes in [[GFAP]] immunoreactivity: Young versus mature adult Wistar rats. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31404554 |full-text-url=https://sci-hub.do/10.1016/j.mad.2019.111128 }} ==CGA== * {{medline-title |title=Safety and efficacy of preoperative chemoradiotherapy in fit older patients with intermediate or locally advanced rectal cancer evaluated by comprehensive geriatric assessment: A planned interim analysis of a multicenter, phase II trial. |date=04.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33160954 |full-text-url=https://sci-hub.do/10.1016/j.jgo.2020.10.016 }} * {{medline-title |title=The Protective Effect of Chlorogenic Acid on Vascular Senescence via the Nrf2/HO-1 Pathway. |date=25.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32630570 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350250 }} * {{medline-title |title=Association between comprehensive geriatric assessment and short-term outcomes among older adult patients with stroke: A nationwide retrospective cohort study using propensity score and instrumental variable methods. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32566923 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298723 }} * {{medline-title |title=Interventions to Improve Clinical Outcomes in Older Adults Admitted to a Surgical Service: A Systematic Review and Meta-analysis. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32417101 |full-text-url=https://sci-hub.do/10.1016/j.jamda.2020.03.023 }} * {{medline-title |title=A Computerized Frailty Assessment Tool at Points-of-Care: Development of a Standalone Electronic Comprehensive Geriatric Assessment/Frailty Index (eFI-[[CGA]]). |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32296673 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137764 }} * {{medline-title |title=Allocating patients to geriatric medicine wards in a tertiary university hospital in England: A service evaluation of the Specialist Advice for the Frail Elderly (SAFE) team. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31942488 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880728 }} * {{medline-title |title=Role of Frailty on Risk Stratification in Cardiac Surgery and Procedures. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31894551 |full-text-url=https://sci-hub.do/10.1007/978-3-030-33330-0_11 }} * {{medline-title |title=Developing an objective structured clinical examination in comprehensive geriatric assessment - A pilot study. |date=05-08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31745004 |full-text-url=https://sci-hub.do/10.4103/efh.EfH_111_18 }} * {{medline-title |title=How do doctors choose treatment for older gynecological cancer patients? A Japanese Gynecologic Oncology Group survey of gynecologic oncologists. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31728682 |full-text-url=https://sci-hub.do/10.1007/s10147-019-01574-z }} * {{medline-title |title=Validation of the Pictorial Fit-Frail Scale in a memory clinic setting. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31524122 |full-text-url=https://sci-hub.do/10.1017/S1041610219000905 }} * {{medline-title |title=Impact of Resolution of Hyponatremia on Neurocognitive and Motor Performance in Geriatric Patients. |date=29.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31467370 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715723 }} * {{medline-title |title=Health outcome of older hospitalized patients in internal medicine environments evaluated by Identification of Seniors at Risk (ISAR) screening and geriatric assessment. |date=14.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31412787 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694685 }} ==TH== * {{medline-title |title=Thyroid hormone signaling is associated with physical performance, muscle mass, and strength in a cohort of oldest-old: results from the Mugello study. |date=21.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33219914 |full-text-url=https://sci-hub.do/10.1007/s11357-020-00302-0 }} * {{medline-title |title=Social Environment Ameliorates Behavioral and Immune Impairments in Tyrosine Hydroxylase Haploinsufficient Female Mice. |date=09.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32772235 |full-text-url=https://sci-hub.do/10.1007/s11481-020-09947-2 }} * {{medline-title |title=Mechanism of thyroid hormone signaling in skeletal muscle of aging mice. |date=27.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32720201 |full-text-url=https://sci-hub.do/10.1007/s12020-020-02428-9 }} * {{medline-title |title=Longitudinal changes in bone mineral density and trabecular bone score in Korean adults: a community-based prospective study. |date=03.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32621253 |full-text-url=https://sci-hub.do/10.1007/s11657-020-00731-6 }} * {{medline-title |title=Quantitative proteomic profiling of the rat substantia nigra places glial fibrillary acidic protein at the hub of proteins dysregulated during aging: Implications for idiopathic Parkinson's disease. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32270889 |full-text-url=https://sci-hub.do/10.1002/jnr.24622 }} * {{medline-title |title=Withaferin-A Protects the Nigral Dopamine Neuron and Recovers Motor Activity in Aged Rats. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31982873 |full-text-url=https://sci-hub.do/10.1159/000505183 }} * {{medline-title |title=Effects of physical activity on bone mineral density in older adults: Korea National Health and Nutrition Examination Survey, 2008-2011. |date=26.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31655946 |full-text-url=https://sci-hub.do/10.1007/s11657-019-0655-5 }} * {{medline-title |title=Age-Related Resistance to Thyroid Hormone Action. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31512083 |full-text-url=https://sci-hub.do/10.1007/s40266-019-00711-7 }} * {{medline-title |title=Age-Dependent Changes in Glucose Homeostasis in Male Deiodinase Type 2 Knockout Zebrafish. |date=01.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31504428 |full-text-url=https://sci-hub.do/10.1210/en.2019-00445 }} * {{medline-title |title=Age effect on thyroid hormone brain response in male mice. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31494803 |full-text-url=https://sci-hub.do/10.1007/s12020-019-02078-6 }} * {{medline-title |title=Aging Is Associated with Low Thyroid State and Organ-Specific Sensitivity to Thyroxine. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31441387 |full-text-url=https://sci-hub.do/10.1089/thy.2018.0377 }} ==SOD2== * {{medline-title |title=Astaxanthin Counteracts Vascular Calcification In Vitro Through an Early Up-Regulation of [[SOD2]] Based on a Transcriptomic Approach. |date=12.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33198315 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698184 }} * {{medline-title |title=Alginate Oligosaccharide Prevents against D-galactose-mediated Cataract in C57BL/6J Mice via Regulating Oxidative Stress and Antioxidant System. |date=06.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33153341 |full-text-url=https://sci-hub.do/10.1080/02713683.2020.1842456 }} * {{medline-title |title=Protoflavones in melanoma therapy: Prooxidant and pro-senescence effect of protoapigenone and its synthetic alkyl derivative in A375 cells. |date=01.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32931795 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118419 }} * {{medline-title |title=Ginsenoside Rg1 protects against Sca-1 HSC/HPC cell aging by regulating the SIRT1-FOXO3 and SIRT3-[[SOD2]] signaling pathways in a γ-ray irradiation-induced aging mice model. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32765665 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388550 }} * {{medline-title |title=Almond Skin Extracts and Chlorogenic Acid Delay Chronological Aging and Enhanced Oxidative Stress Response in Yeast. |date=28.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32481725 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345664 }} * {{medline-title |title=Opposing p53 and mTOR/AKT promote an in vivo switch from apoptosis to senescence upon telomere shortening in zebrafish. |date=19.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32427102 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237213 }} * {{medline-title |title=Bioactive peptides derived from crimson snapper and in vivo anti-aging effects on fat diet-induced high fat Drosophila melanogaster. |date=29.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31844865 |full-text-url=https://sci-hub.do/10.1039/c9fo01414d }} * {{medline-title |title=Ellagic acid prolongs the lifespan of Drosophila melanogaster. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31786733 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031466 }} * {{medline-title |title=Chlorella vulgaris modulates the expression of senescence-associated genes in replicative senescence of human diploid fibroblasts. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31642042 |full-text-url=https://sci-hub.do/10.1007/s11033-019-05140-8 }} * {{medline-title |title=Age-Associated Changes in Antioxidants and Redox Proteins of Rat Heart. |date=30.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31647296 |full-text-url=https://sci-hub.do/10.33549/physiolres.934170 }} * {{medline-title |title=Impact of curcumin on replicative and chronological aging in the Saccharomyces cerevisiae yeast. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31659616 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942599 }} ==MB== * {{medline-title |title=Probing menstrual bloodstain aging with fluorescence spectroscopy. |date=13.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33279406 |full-text-url=https://sci-hub.do/10.1016/j.saa.2020.119172 }} * {{medline-title |title=Effect of physical exercise and medication on enhancing cognitive function in older adults with vascular risk. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32989840 |full-text-url=https://sci-hub.do/10.1111/ggi.14048 }} * {{medline-title |title=A novel indenone derivative selectively induces senescence in MDA-[[MB]]-231 (breast adenocarcinoma) cells. |date=01.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32956706 |full-text-url=https://sci-hub.do/10.1016/j.cbi.2020.109250 }} * {{medline-title |title=Improved Autophagic Flux in Escapers from Doxorubicin-Induced Senescence/Polyploidy of Breast Cancer Cells. |date=24.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32846959 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504443 }} * {{medline-title |title=Lifespan regulation in α/β posterior neurons of the fly mushroom bodies by Rab27. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32627932 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431830 }} * {{medline-title |title=Tailored Functionalized Magnetic Nanoparticles to Target Breast Cancer Cells Including Cancer Stem-Like Cells. |date=29.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32485849 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352336 }} * {{medline-title |title="Mitotic Slippage" and Extranuclear DNA in Cancer Chemoresistance: A Focus on Telomeres. |date=16.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32316332 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215480 }} * {{medline-title |title=Diversity of the Senescence Phenotype of Cancer Cells Treated with Chemotherapeutic Agents. |date=23.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31771226 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952928 }} * {{medline-title |title=Downregulation of the inflammatory network in senescent fibroblasts and aging tissues of the long-lived and cancer-resistant subterranean wild rodent, Spalax. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31605433 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974727 }} * {{medline-title |title=Quantification of the health-status of the Dutch Labrador retriever population. |date=01.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31494529 |full-text-url=https://sci-hub.do/10.1016/j.prevetmed.2019.104764 }} * {{medline-title |title=Conjugated Physiological Resveratrol Metabolites Induce Senescence in Breast Cancer Cells: Role of p53/p21 and p16/Rb Pathways, and ABC Transporters. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31441212 |full-text-url=https://sci-hub.do/10.1002/mnfr.201900629 }} ==PC== * {{medline-title |title=Blended home-based exercise and dietary protein in community-dwelling older adults: a cluster randomized controlled trial. |date=26.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33103379 |full-text-url=https://sci-hub.do/10.1002/jcsm.12634 }} * {{medline-title |title=Right ventricular diastolic function in aging: a head-to-head comparison between phase-contrast MRI and Doppler echocardiography. |date=27.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32980983 |full-text-url=https://sci-hub.do/10.1007/s10554-020-02040-y }} * {{medline-title |title=Pulse Width and Implantable Pulse Generator Longevity in Pallidal Deep Brain Stimulation for Dystonia: A Population-Based Comparative Effectiveness Study. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32668433 |full-text-url=https://sci-hub.do/10.1159/000508794 }} * {{medline-title |title=Gemcitabine plus nab-paclitaxel with initial dose reduction for older patients with advanced pancreatic cancer. |date=20.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32576518 |full-text-url=https://sci-hub.do/10.1016/j.jgo.2020.06.017 }} * {{medline-title |title=Protective effects of 17-β-oestradiol and phytoestrogen on age-induced oxidative stress and inhibition of surfactant synthesis in rat type II pneumocytes. |date=02.2021 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32314935 |full-text-url=https://sci-hub.do/10.1080/09637486.2020.1757044 }} * {{medline-title |title=Pacing During 200-m Competitive Masters Swimming. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32271289 |full-text-url=https://sci-hub.do/10.1519/JSC.0000000000003621 }} * {{medline-title |title=Prostate cancer in Pennsylvania: The role of older age at diagnosis, aggressiveness, and environmental risk factors on treatment and mortality using data from the Pennsylvania Cancer Registry. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32212232 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221418 }} * {{medline-title |title=Extracranial versus intracranial hydro-hemodynamics during aging: a [[PC]]-MRI pilot cross-sectional study. |date=14.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31931818 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958565 }} * {{medline-title |title=Age-specific health-related quality of life in disease-free long-term prostate cancer survivors versus male population controls-results from a population-based study. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31736000 |full-text-url=https://sci-hub.do/10.1007/s00520-019-05120-5 }} * {{medline-title |title=Cross-Linked Polyphenol-Based Drug Nano-Self-Assemblies Engineered to Blockade Prostate Cancer Senescence. |date=23.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31553876 |full-text-url=https://sci-hub.do/10.1021/acsami.9b14738 }} * {{medline-title |title=An Immersive Virtual Reality Platform for Assessing Spatial Navigation Memory in Predementia Screening: Feasibility and Usability Study. |date=03.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31482851 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751096 }}
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