Редактирование: AQP7

Aquaporin-7 (AQP-7) (Aquaglyceroporin-7) (Aquaporin adipose) (AQPap) (Aquaporin-7-like) [AQP7L] [AQP9]

==Publications==

{{medline-entry
|title=Distribution and roles of aquaporins in salivary glands.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/16537077
|abstract=Salivary glands are involved in secretion of saliva, which is known to participate in the protection and hydratation of mucosal structures within the oral cavity, oropharynx and oesophagus, the initiation of digestion, some antimicrobial defence, and the protection from chemical and mechanical stress. Saliva secretion is a watery fluid containing electrolytes and a mixture of proteins and can be stimulated by muscarinic and adrenergic agonists. Since water movement is involved in saliva secretion, the expression, localization and function of aquaporins (AQPs) have been studied in salivary glands. This review will focus on the expression, localization and functional roles of the AQPs identified in salivary glands. The presence of [[AQP1]], [[AQP5]] and [[AQP8]] has been generally accepted by many, while the presence of [[AQP3]], [[AQP4]], [[AQP6]] and [[AQP7]] still remains controversial. Functionally, [[AQP5]] seems to be the only AQP thus far to be clearly playing a major role in the salivary secretion process. Modifications in AQPs expression and/or distribution have been reported in xerostomic conditions.
|mesh-terms=* Aging
* Animals
* Aquaporin 5
* Aquaporins
* Biological Transport, Active
* Cell Line
* Diabetes Mellitus
* Head and Neck Neoplasms
* Humans
* Protein Transport
* Salivary Glands
* Sjogren's Syndrome
* Water
* Xerostomia

|full-text-url=https://sci-hub.do/10.1016/j.bbamem.2006.01.022
}}
{{medline-entry
|title=Expression patterns of aquaporins in the inner ear: evidence for concerted actions of multiple types of aquaporins to facilitate water transport in the cochlea.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/12031518
|abstract=Water transport between the perilymph and endolymph is important in regulations of volume and osmotic pressure of the inner ear labyrinth. It is now known that expression of water channels (aquaporins or AQPs) in the cell membrane dramatically increases the ability of water to cross epithelial cells. The aims of the current study were to investigate the cellular localization of AQPs by immunolabeling, and to study the developmental expression and relative abundance of various subtypes of AQPs. We report here that [[AQP3]], [[AQP7]] and [[AQP9]] were expressed in the inner ear. Specific subtypes of AQPs were found in discrete regions expressed by both epithelial cells and fibrocytes in cochlear and vestibular organs. Semi-quantitative measurements showed that [[AQP4]] and [[AQP1]] were the two most abundantly expressed AQP subtypes in the inner ear, and their expressions were dramatically upregulated during development. These data showed a highly localized and largely non-overlapping distribution pattern for different subtypes of AQPs in the inner ear, suggesting the existence of regional subtype-specific water transport pathways, and global regulation of water transport in the inner ear may require concerted actions of multiple types of AQPs.
|mesh-terms=* Aging
* Animals
* Aquaporins
* Biological Transport
* Cochlea
* Ear, Inner
* Endolymphatic Sac
* Immunohistochemistry
* Mice
* Protein Isoforms
* Vestibule, Labyrinth
* Water

|full-text-url=https://sci-hub.do/10.1016/s0378-5955(02)00288-5
}}
{{medline-entry
|title=Expression of aquaporins 7 and 8 in the developing rat testis.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/11380332
|abstract=Aquaporin (AQP) is a molecule that facilitates water permeability through cell membranes and is widely distributed in the mammalian body. Among members of the AQP family, [[AQP7]] and [[AQP8]] are predominantly expressed in the testis. This paper examined the expression of these two AQPs in the developing rat testis, using northern blot and immunohistochemistry to visualize their roles during the progression of spermatogenesis in the developing testis. In adult rats, expression of [[AQP7]] was localized to spermatids, whereas [[AQP8]] protein was observed in spermatocytes. In the developing testis, transcripts of [[AQP7]] became detectable between 23 and 25 days post-partum, when round spermatids have been reported to appear. On the other hand, [[AQP8]] mRNA was first detected between 13 and 16 days post-partum, consistent with the reported first appearance of spermatocytes (13-14 days). [[AQP7]] and [[AQP8]] proteins were detectable at 28 days post-partum. The results suggest that [[AQP7]] and [[AQP8]] appear in the testis in accordance with the maturation of germ cells, and are involved in spermatogenesis.
|mesh-terms=* Aging
* Animals
* Aquaporins
* Blotting, Northern
* Gene Expression
* Immunohistochemistry
* Ion Channels
* Male
* RNA, Messenger
* Rats
* Rats, Sprague-Dawley
* Spermatids
* Spermatocytes
* Spermatogenesis
* Testis

|full-text-url=https://sci-hub.do/10.1046/j.1439-0272.2001.00443.x
}}