Редактирование: Публикации о генах и старении (titles) (раздел)

==ACE2==

{{medline-entry
|title=How Does SARS-CoV-2 Affect the Central Nervous System? A Working Hypothesis.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33304284


|keywords=* ACE2
* Alzheimer disease
* Ang(1-7)/Mas
* COVID-19
* RAAS
* SARS-CoV
* brain aging
* neurodegenerative and psychiatric disorders abstract
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701095
}}
{{medline-entry
|title=Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33112891

|mesh-terms=* Aging
* Angiotensin-Converting Enzyme 2
* Betacoronavirus
* Binding Sites
* COVID-19
* Carrier Proteins
* Computational Biology
* Coronavirus Infections
* Female
* Gene Expression Regulation, Enzymologic
* Gene Ontology
* Humans
* Interferons
* Lung
* Male
* Metalloproteases
* Neovascularization, Physiologic
* Organ Specificity
* Pandemics
* Peptidyl-Dipeptidase A
* Pneumonia, Viral
* Promoter Regions, Genetic
* RNA, Messenger
* Receptors, Virus
* Renin-Angiotensin System
* SARS-CoV-2
* Sex Characteristics
* Single-Cell Analysis
* Transcription Factors
* Transcription Initiation Site
* Virus Attachment

|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592753
}}
{{medline-entry
|title=A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32854108

|mesh-terms=* Aging
* Angiotensin-Converting Enzyme 2
* Animals
* Betacoronavirus
* COVID-19
* COVID-19 Vaccines
* Coronavirus Infections
* Disease Models, Animal
* Female
* Forkhead Transcription Factors
* Humans
* Interferon-alpha
* Interferons
* Interleukins
* Male
* Mice
* Mice, Inbred BALB C
* Mice, Transgenic
* Models, Molecular
* Pandemics
* Peptidyl-Dipeptidase A
* Pneumonia, Viral
* Receptors, Virus
* SARS-CoV-2
* Viral Vaccines

|full-text-url=https://sci-hub.do/10.1038/s41586-020-2708-8
}}
{{medline-entry
|title=COVID-19 and Senotherapeutics: Any Role for the Naturally-occurring Dipeptide Carnosine?
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32765939


|keywords=* acetyl-carnosine
* aging
* carnosine
* inflammation
* lungs
* olfaction
* virus
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390525
}}
{{medline-entry
|title=The dual impact of [[ACE2]] in COVID-19 and ironical actions in geriatrics and pediatrics with possible therapeutic solutions.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32653522

|mesh-terms=* Age Factors
* Aged
* Aged, 80 and over
* Angiotensin-Converting Enzyme 2
* Anti-Inflammatory Agents
* Betacoronavirus
* COVID-19
* Child
* Child, Preschool
* Coronavirus
* Coronavirus Infections
* Female
* Geriatrics
* Humans
* Infant
* Infant, Newborn
* Male
* Pandemics
* Pediatrics
* Peptidyl-Dipeptidase A
* Pneumonia, Viral
* Protein Binding
* Receptors, Virus
* Renin-Angiotensin System
* SARS-CoV-2
* Severe Acute Respiratory Syndrome
* Virus Internalization
|keywords=* ACE2
* Angiotensin 2
* Angiotensin-(1–7)
* Corona virus
* Glycoprotein spikes
* RAAS system
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347488
}}
{{medline-entry
|title=The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of "inflame-aging".
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32529477

|mesh-terms=* Adipocytes
* Age Factors
* Aged
* Aging
* Angiotensin II Type 2 Receptor Blockers
* Autophagy
* Betacoronavirus
* COVID-19
* Cellular Senescence
* Coronavirus Infections
* Cytokine Release Syndrome
* Cytokines
* Humans
* Immune System
* Inflammation
* Pandemics
* Pneumonia, Viral
* Reactive Oxygen Species
* Receptor, Angiotensin, Type 2
* SARS-CoV-2
* Vitamin D
* Vitamin D Deficiency
|keywords=* ACE2 receptor
* Autophagy
* COVID-19
* Cytokine storm
* Senescent cell
* Vitamin D
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289226
}}
{{medline-entry
|title=Decoding SARS-CoV-2 hijacking of host mitochondria in COVID-19 pathogenesis.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32510973

|mesh-terms=* Adaptive Immunity
* Angiotensin-Converting Enzyme 2
* Animals
* Betacoronavirus
* COVID-19
* Coronavirus Infections
* DNA, Mitochondrial
* Gene Expression Regulation, Viral
* Host Microbial Interactions
* Humans
* Immunity, Innate
* Mitochondria
* Pandemics
* Peptidyl-Dipeptidase A
* Pneumonia, Viral
* RNA, Viral
* SARS-CoV-2
* Virus Replication
|keywords=* COVID-19
* SARS-CoV
* aging
* coronavirus
* mitochondria
* mitochondrial DNA
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381712
}}
{{medline-entry
|title=A Mouse Model of SARS-CoV-2 Infection and Pathogenesis.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32485164

|mesh-terms=* Aging
* Angiotensin-Converting Enzyme 2
* Animals
* Betacoronavirus
* Brain
* COVID-19
* CRISPR-Cas Systems
* Coronavirus Infections
* Cytokines
* Disease Models, Animal
* Gene Knock-In Techniques
* Lung
* Lung Diseases, Interstitial
* Mice, Inbred C57BL
* Nose
* Pandemics
* Peptidyl-Dipeptidase A
* Pneumonia, Viral
* RNA, Viral
* SARS-CoV-2
* Stomach
* Trachea
* Viral Load
* Virus Replication
|keywords=* SARS-CoV-2
* angiotensin-converting enzyme II
* hACE2-KI/NIFDC
* mouse model
* pathogenesis
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250783
}}
{{medline-entry
|title=COVID-19-associated cardiovascular morbidity in older adults: a position paper from the Italian Society of Cardiovascular Researches.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32430627

|mesh-terms=* Age Factors
* Aged
* Betacoronavirus
* COVID-19
* Cardiovascular Diseases
* Coronavirus Infections
* Female
* Humans
* Italy
* Male
* Middle Aged
* Pandemics
* Pneumonia, Viral
* Risk Factors
* SARS-CoV-2
|keywords=* Acute myocardial injury
* Aging
* COVID-19
* Cardiovascular system
* Frailty
* SARS-CoV-2
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237344
}}
{{medline-entry
|title=Gut microbiota and Covid-19- possible link and implications.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32430279

|mesh-terms=* Aging
* Betacoronavirus
* COVID-19
* Coronavirus Infections
* Diet
* Dysbiosis
* Gastrointestinal Microbiome
* Gastrointestinal Tract
* Homeostasis
* Humans
* Immunity
* Lung
* Pandemics
* Pneumonia, Viral
* SARS-CoV-2
|keywords=* Covid-19
* Diet
* Dysbiosis
* Gut microbiome
* Immunity
* Lung microbiota
* SARS-CoV-2
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217790
}}
{{medline-entry
|title=Inflamm-aging: Why older men are the most susceptible to SARS-CoV-2 complicated outcomes.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32389499

|mesh-terms=* Aged
* Aged, 80 and over
* Aging
* Angiotensin-Converting Enzyme 2
* Antibodies, Monoclonal, Humanized
* Betacoronavirus
* COVID-19
* Comorbidity
* Coronavirus Infections
* Female
* Humans
* Inflammation
* Interferon Type I
* Interleukin-6
* Male
* Pandemics
* Peptidyl-Dipeptidase A
* Pneumonia, Viral
* SARS-CoV-2
* Severe Acute Respiratory Syndrome
|keywords=* COVID-19
* Cardiovascular diseases
* Host-directed therapies
* Inflamm-aging
* SARS-CoV-2
* interleukin-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252014
}}
{{medline-entry
|title=Restoration of the Renin-Angiotensin System Balance Is a Part of the Effect of Fasting on Cardiovascular Rejuvenation: Role of Age and Fasting Models.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31571520


|keywords=* aging
* cardiac hypertrophy index
* intermittent fasting
* renin–angiotensin system (RAS)
|full-text-url=https://sci-hub.do/10.1089/rej.2019.2254
}}
{{medline-entry
|title=Angiotensin 1-7 alleviates aging-associated muscle weakness and bone loss, but is not associated with accelerated aging in [[ACE2]]-knockout mice.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31519791

|mesh-terms=* Adipose Tissue
* Aging
* Angiotensin I
* Angiotensin-Converting Enzyme 2
* Animals
* Body Weight
* Bone Resorption
* Cyclin-Dependent Kinase Inhibitor p16
* Forelimb
* Gene Deletion
* Hand Strength
* Male
* Mice, Inbred C57BL
* Mice, Knockout
* Muscle Weakness
* Muscles
* Organ Size
* PAX3 Transcription Factor
* Peptide Fragments
* Peptidyl-Dipeptidase A
* Proto-Oncogene Proteins
* Receptors, G-Protein-Coupled
* Renin-Angiotensin System
* Time Factors
|keywords=* Angiotensin 1-7
* Angiotensin Converting Enzyme 2
* Mas receptor
* Muscle weakness
* osteoporosis
|full-text-url=https://sci-hub.do/10.1042/CS20190573
}}