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Aging genes 60-69
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==IL6== * {{medline-title |title=[[REV1]] inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks. |date=17.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168727 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682577 }} * {{medline-title |title=[[IL1B]] triggers inflammatory cytokine production in bovine oviduct epithelial cells and induces neutrophil accumulation via [[CCL2]]. |date=25.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33099841 |full-text-url=https://sci-hub.do/10.1111/aji.13365 }} * {{medline-title |title=Basic immunology may lead to translational therapeutic rationale: SARS-CoV-2 and rheumatic diseases. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32645207 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404583 }} * {{medline-title |title=[[ATM]]-deficient neural precursors develop senescence phenotype with disturbances in autophagy. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32621937 |full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111296 }} * {{medline-title |title=The microRNA-34a-Induced Senescence-Associated Secretory Phenotype (SASP) Favors Vascular Smooth Muscle Cells Calcification. |date=23.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32585876 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352675 }} * {{medline-title |title=Impact of Influenza on Pneumococcal Vaccine Effectiveness during [i]Streptococcus pneumoniae[/i] Infection in Aged Murine Lung. |date=11.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32545261 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349919 }} * {{medline-title |title=Reacquisition of a spindle cell shape does not lead to the restoration of a youthful state in senescent human skin fibroblasts. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32533368 |full-text-url=https://sci-hub.do/10.1007/s10522-020-09886-8 }} * {{medline-title |title=Patterns of multi-domain cognitive aging in participants of the Long Life Family Study. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32514870 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525612 }} * {{medline-title |title=Inflamma-miR-21 Negatively Regulates Myogenesis during Ageing. |date=23.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32340146 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222422 }} * {{medline-title |title=p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to non-nucleoside reverse transcriptase inhibitors. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32272174 |full-text-url=https://sci-hub.do/10.1016/j.antiviral.2020.104784 }} * {{medline-title |title=The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of [[SIRT1]]. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32047577 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003265 }} * {{medline-title |title=Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season. |date=21.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31864349 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925900 }} * {{medline-title |title=Advanced Age Is Associated with Iron Dyshomeostasis and Mitochondrial DNA Damage in Human Skeletal Muscle. |date=27.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31783583 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953082 }} * {{medline-title |title=Cholest-4,6-Dien-3-One Promote Epithelial-To-Mesenchymal Transition (EMT) in Biliary Tree Stem/Progenitor Cell Cultures In Vitro. |date=15.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31731674 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912632 }} * {{medline-title |title=Single xenotransplant of rat brown adipose tissue prolonged the ovarian lifespan of aging mice by improving follicle survival. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31389140 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826128 }} * {{medline-title |title=Intestinal stem cells acquire premature senescence and senescence associated secretory phenotype concurrent with persistent DNA damage after heavy ion radiation in mice. |date=25.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31239406 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629005 }} * {{medline-title |title=N-acetylcysteine and alpha-lipoic acid improve antioxidant defenses and decrease oxidative stress, inflammation and serum lipid levels in ovariectomized rats via estrogen-independent mechanisms. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30951973 |full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2019.02.012 }} * {{medline-title |title=Age-dependent hepatic alterations induced by a high-fat high-fructose diet. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30874869 |full-text-url=https://sci-hub.do/10.1007/s00011-019-01223-1 }} * {{medline-title |title=Protective effects of a novel facial cream against environmental pollution: in vivo and in vitro assessment. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30519068 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237134 }} * {{medline-title |title=Expression of pro- and anti-inflammatory cytokines and chemokines during the ovulatory cycle and effects of aging on their expression in the uterine mucosa of laying hens. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269026 |full-text-url=https://sci-hub.do/10.1016/j.cyto.2018.09.015 }} * {{medline-title |title=Torquetenovirus (TTV) load is associated with mortality in Italian elderly subjects. |date=02.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30223047 |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.09.003 }} * {{medline-title |title=Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29890178 |full-text-url=https://sci-hub.do/10.1016/j.mad.2018.06.002 }} * {{medline-title |title=Composition and richness of the serum microbiome differ by age and link to systemic inflammation. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29869736 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060185 }} * {{medline-title |title=Interleukin 6 Knockout Inhibits Aging-Related Accumulation of p53 in the Mouse Myocardium. |date=16.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29718116 |full-text-url=https://sci-hub.do/10.1093/gerona/gly105 }} * {{medline-title |title=Age Dependent Hypothalamic and Pituitary Responses to Novel Environment Stress or Lipopolysaccharide in Rats. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615881 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868128 }} * {{medline-title |title=Sulodexide Slows Down the Senescence of Aortic Endothelial Cells Exposed to Serum from Patients with Peripheral Artery Diseases. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29587258 |full-text-url=https://sci-hub.do/10.1159/000488167 }} * {{medline-title |title=Dexamethasone downregulates [[SIRT1]] and [[IL6]] and upregulates [[EDN1]] genes in stem cells derived from gingivae via the AGE/RAGE pathway. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29302812 |full-text-url=https://sci-hub.do/10.1007/s10529-017-2493-0 }} * {{medline-title |title=Senescence promotes in vivo reprogramming through p16 and IL-6. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280266 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847859 }} * {{medline-title |title=Predictive value of multiple cytokines and chemokines for mortality in an admixed population: 15-year follow-up of the Bambui-Epigen (Brazil) cohort study of aging. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28803133 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.002 }} * {{medline-title |title=Voluntary running exercise protects against sepsis-induced early inflammatory and pro-coagulant responses in aged mice. |date=08.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28789683 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549433 }} * {{medline-title |title=Cooperation between p21 and Akt is required for p53-dependent cellular senescence. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28691365 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595696 }} * {{medline-title |title=Low Oxygen Consumption is Related to a Hypomethylation and an Increased Secretion of IL-6 in Obese Subjects with Sleep Apnea-Hypopnea Syndrome. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28675894 |full-text-url=https://sci-hub.do/10.1159/000478276 }} * {{medline-title |title=Senescence-associated IL-6 and IL-8 cytokines induce a self- and cross-reinforced senescence/inflammatory milieu strengthening tumorigenic capabilities in the MCF-7 breast cancer cell line. |date=04.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28472950 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418812 }} * {{medline-title |title=Skeletal muscle morphology and regulatory signalling in endurance-trained and sedentary individuals: The influence of ageing. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28411009 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.04.001 }} * {{medline-title |title=Cellular Senescence in Mouse Hippocampus After Irradiation and the Role of p53 and p21. |date=01.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28340115 |full-text-url=https://sci-hub.do/10.1093/jnen/nlx006 }} * {{medline-title |title=Chronic Resveratrol Treatment Inhibits MRC5 Fibroblast SASP-Related Protumoral Effects on Melanoma Cells. |date=01.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28329136 |full-text-url=https://sci-hub.do/10.1093/gerona/glw336 }} * {{medline-title |title=Analysis of molecular networks and targets mining of Chinese herbal medicines on anti-aging. |date=28.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28031022 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198498 }} * {{medline-title |title=Aging promotes neoplastic disease through effects on the tissue microenvironment. |date=06.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27929382 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270675 }} * {{medline-title |title=The integration of epigenetics and genetics in nutrition research for CVD risk factors. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27919301 |full-text-url=https://sci-hub.do/10.1017/S0029665116000823 }} * {{medline-title |title=Serum Immune Mediators Independently Associate with Atherosclerosis in the Left (But Not Right) Carotid Territory of Older Individuals. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27554076 |full-text-url=https://sci-hub.do/10.1016/j.jstrokecerebrovasdis.2016.07.047 }} * {{medline-title |title=ATF6α regulates morphological changes associated with senescence in human fibroblasts. |date=18.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27563820 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356513 }} * {{medline-title |title=Stimulation of cellular senescent processes, including secretory phenotypes and anti-oxidant responses, after androgen deprivation therapy in human prostate cancer. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27329245 |full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2016.06.007 }} * {{medline-title |title=Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27294501 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983298 }} * {{medline-title |title=Inflammation in Lafora Disease: Evolution with Disease Progression in Laforin and Malin Knock-out Mouse Models. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27041370 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472678 }} * {{medline-title |title=No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26946122 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841709 }} * {{medline-title |title=Bone biology-related gingival transcriptome in ageing and periodontitis in non-human primates. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26859687 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844783 }} * {{medline-title |title=CNS-wide Sexually Dimorphic Induction of the Major Histocompatibility Complex 1 Pathway With Aging. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26786204 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155655 }} * {{medline-title |title=[[TNF]] Drives Monocyte Dysfunction with Age and Results in Impaired Anti-pneumococcal Immunity. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26766566 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713203 }} * {{medline-title |title=Neuroimmune and Neuropathic Responses of Spinal Cord and Dorsal Root Ganglia in Middle Age. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26241743 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524632 }} * {{medline-title |title=LIPID PROFILE AND CYTOKINES INTERACTIONS DURING SUCCESSFUL AGING. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26087730 }} * {{medline-title |title=Gene expression markers of age-related inflammation in two human cohorts. |date=10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26087330 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600657 }} * {{medline-title |title=Age-independent effects of hyaluronan amide derivative and growth hormone on human osteoarthritic chondrocytes. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26075645 |full-text-url=https://sci-hub.do/10.3109/03008207.2015.1047928 }} * {{medline-title |title=Evidence of cellular senescence during the development of estrogen-induced pituitary tumors. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25792544 |full-text-url=https://sci-hub.do/10.1530/ERC-14-0333 }} * {{medline-title |title=TRIM28/KAP1 regulates senescence. |date=11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25160591 |full-text-url=https://sci-hub.do/10.1016/j.imlet.2014.08.011 }} * {{medline-title |title=The expression of [[IL6]] and 21 in crossbred calves upregulated by inactivated trivalent FMD vaccine. |date=03.04.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24555796 |full-text-url=https://sci-hub.do/10.1080/10495398.2013.834826 }} * {{medline-title |title=Depressive symptoms are associated with reduced neutrophil function in hip fracture patients. |date=10.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23876747 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781604 }} * {{medline-title |title=IκBζ is a regulator of the senescence-associated secretory phenotype in DNA damage- and oncogene-induced senescence. |date=15.08.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23781024 |full-text-url=https://sci-hub.do/10.1242/jcs.128835 }} * {{medline-title |title=Exercise-induced hippocampal anti-inflammatory response in aged rats. |date=10.05.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23663962 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657539 }} * {{medline-title |title=Effects of a nutraceutical formulation based on the combination of antioxidants and ω-3 essential fatty acids in the expression of inflammation and immune response mediators in tears from patients with dry eye disorders. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23430672 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573824 }} * {{medline-title |title=[[TNF]]-α, [[IL6]], and [[IL10]] polymorphisms and the effect of physical exercise on inflammatory parameters and physical performance in elderly women. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23430759 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824985 }}
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