Редактирование: Публикации о генах и старении (titles) (раздел)

==STAT3==

{{medline-entry
|title=Dietary Restriction Suppresses Steatosis-Associated Hepatic Tumorigenesis in Hepatitis C Virus Core Gene Transgenic Mice.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33083279


|keywords=* Cyclin D1
* NF-κB
* STAT3
* Senescence
* p62/SQSTM1
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548900
}}
{{medline-entry
|title=Skeletal glucocorticoid signalling determines leptin resistance and obesity in aging mice.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33045434


|keywords=* Aging
* Appetite
* Glucocorticoid
* Leptin
* Obesity
* Osteoblast
* Osteocyte
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596342
}}
{{medline-entry
|title=AMPK alleviates oxidative stress‑induced premature senescence via inhibition of NF-κB/[[STAT3]] axis-mediated positive feedback loop.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32882228


|keywords=* AMPK
* NF-κB/STAT3 signalling
* Oxidative stress
* SASP
* Senescence
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111347
}}
{{medline-entry
|title=Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through [[STAT3]] activation.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32848054

|mesh-terms=* Aging
* Animals
* Cell Differentiation
* Cell Proliferation
* Computational Biology
* Gene Expression Regulation
* Glucosamine
* Hippocampus
* Mice
* Neural Stem Cells
* Neurogenesis
* Neuroglia
* STAT3 Transcription Factor
* Sequence Analysis, RNA
|keywords=* O-GlcNAcylation
* aging
* gliogenesis
* neural stem cells
* neurogenesis
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486730
}}
{{medline-entry
|title=Cell Death by Gallotannin Is Associated with Inhibition of the JAK/STAT Pathway in Human Colon Cancer Cells.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32714471


|keywords=* Apoptosis
* JAK/STAT
* caspase
* colon cancer
* gallotannin
* senescence
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378856
}}
{{medline-entry
|title=The effect of interleukin 6 deficiency on myocardial signal transduction pathways activation induced by bacterial lipopolysaccharide in young and old mice.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32693349


|keywords=* Aging
* For review: bacterial lipolisacharide (LPS)
* Heart
* Inflammation
* Interleukin-6
* Signal transduction
|full-text-url=https://sci-hub.do/10.1016/j.advms.2020.06.006
}}
{{medline-entry
|title=Silibinin and SARS-CoV-2: Dual Targeting of Host Cytokine Storm and Virus Replication Machinery for Clinical Management of COVID-19 Patients.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32517353


|keywords=* IL-6
* JAK
* coronavirus
* cytokine storm
* remdesivir
* senescence
* stat3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356916
}}
{{medline-entry
|title=Implication of JAK1/[[STAT3]]/SOCS3 Pathway in Aging of Cerebellum of Male Rat: Histological and Molecular study.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32483368

|mesh-terms=* Aging
* Animals
* Caspase 3
* Cerebellum
* Glial Fibrillary Acidic Protein
* Glutathione
* Immunohistochemistry
* Janus Kinase 1
* Male
* Malondialdehyde
* Microscopy, Electron
* Rats
* Rats, Wistar
* STAT3 Transcription Factor
* Signal Transduction
* Suppressor of Cytokine Signaling 3 Protein
* Tumor Necrosis Factor-alpha

|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264275
}}
{{medline-entry
|title=Atorvastatin-induced senescence of hepatocellular carcinoma is mediated by downregulation of hTERT through the suppression of the IL-6/[[STAT3]] pathway.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32257389


|keywords=* Cancer therapy
* Senescence
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105491
}}
{{medline-entry
|title=Deciphering the Molecular Mechanism of Spontaneous Senescence in Primary Epithelial Ovarian Cancer Cells.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32012719


|keywords=* aging biomarkers
* cancer biology
* cellular senescence
* epithelial ovarian cancer
* oxidative stress
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072138
}}
{{medline-entry
|title=Persistent Activation of [[STAT3]] Pathway in the Retina Induced Vision Impairment and Retinal Degenerative Changes in Ageing Mice.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31884637

|mesh-terms=* Aging
* Animals
* Mice
* Mice, Inbred C57BL
* Retina
* Retinal Degeneration
* STAT3 Transcription Factor
* Suppressor of Cytokine Signaling 3 Protein
* Suppressor of Cytokine Signaling Proteins
* Uveitis
|keywords=* EAU
* Experimental autoimmune uveitis
* Retinal dystrophies
* SOCS3
* STAT3
* Transgenic mouse
* Uveitis
|full-text-url=https://sci-hub.do/10.1007/978-3-030-27378-1_58
}}
{{medline-entry
|title=Interleukin-10 induces senescence of activated hepatic stellate cells via [[STAT3]]-p53 pathway to attenuate liver fibrosis.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31730896


|keywords=* Hepatic stellate cells
* Interleukin-10
* Liver fibrosis
* Senescence
* Signal pathway
|full-text-url=https://sci-hub.do/10.1016/j.cellsig.2019.109445
}}