Редактирование: Публикации о генах и старении (titles) (раздел)

==SIRT6==

{{medline-entry
|title=Association between [[SIRT6]] Methylation and Human Longevity in a Chinese Population.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33238266


|keywords=* DNA Methylation
* Longevity
* Messenger RNA
* SIRT6
|full-text-url=https://sci-hub.do/10.1159/000508832
}}
{{medline-entry
|title=The [[SIRT6]] activator MDL-800 improves genomic stability and pluripotency of old murine-derived iPS cells.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33089974


|keywords=* DNA repair
* MDL-800
* SIRT6
* aging
* genome integrity
* pluripotency
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431819
}}
{{medline-entry
|title=Sirtuins as Possible Predictors of Aging and Alzheimer's Disease Development: Verification in the Hippocampus and Saliva.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33098511


|keywords=* Alzheimer’s disease
* aging
* intravital diagnosis
* saliva
* sirtuins
|full-text-url=https://sci-hub.do/10.1007/s10517-020-04986-4
}}
{{medline-entry
|title=Age-related epigenetic drift deregulates [i][[SIRT6]][/i] expression and affects its downstream genes in human peripheral blood mononuclear cells.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32573339


|keywords=* SIRT6
* aging
* interaction network
* longevity
* methylation
* miRNA
* peripheral blood mononuclear cells (PBMCs)
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678931
}}
{{medline-entry
|title=Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32518153


|keywords=* SIRT6
* activator
* aging
* cancer
* cell metabolism
* chromatin
* gene expression
* histone deacetylase (HDAC)
* longevity
* metabolic disorder
* sirtuin
* small molecule
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415977
}}
{{medline-entry
|title=Age-dependent role of [[SIRT6]] in jawbone via regulating senescence and autophagy of bone marrow stromal cells.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32002721

|mesh-terms=* Adult
* Aged
* Aging
* Animals
* Bone Marrow Cells
* Humans
* Jaw
* Male
* Mesenchymal Stem Cells
* Mice
* Mice, Knockout
* Middle Aged
* Osteogenesis
* Sirtuins
|keywords=* Autophagy
* Bone marrow stromal cells
* Jawbone
* Osteoporosis
* SIRT6
* Senescence
|full-text-url=https://sci-hub.do/10.1007/s10735-020-09857-w
}}
{{medline-entry
|title=Mechanism of activation for the sirtuin 6 protein deacylase.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31822559

|mesh-terms=* Allosteric Regulation
* Biocatalysis
* Fatty Acids
* HEK293 Cells
* Histones
* Humans
* Hydrophobic and Hydrophilic Interactions
* Kinetics
* Lipids
* Mutagenesis
* Mutation
* NAD
* Peptides
* Protein Binding
* Protein Conformation
* Sirtuins
* Small Molecule Libraries
|keywords=* SIRT6
* activator
* cancer
* chromatin
* deacetylation
* epigenetics
* histone
* histone deacetylase (HDAC)
* lifespan
* long chain acyl substrate
* longevity
* sirtuin
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996886
}}
{{medline-entry
|title=Proteomics of Long-Lived Mammals.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31737995


|keywords=* SIRT6
* aging
* long-lived mammals
* naked mole rats
* proteomics
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117992
}}
{{medline-entry
|title=Sirtuins and [[SIRT6]] in Carcinogenesis and in Diet.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31591350

|mesh-terms=* Aging
* Animals
* Carcinogenesis
* Diet
* Gene Expression Regulation, Neoplastic
* Humans
* Nanomedicine
* Organ Specificity
* Sirtuins
|keywords=* SIRT6
* cancer
* chemotherapy
* diet
* modulator
* sirtuins
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801518
}}
{{medline-entry
|title=[[SIRT6]]-mediated transcriptional suppression of MALAT1 is a key mechanism for endothelial to mesenchymal transition.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31399301

|mesh-terms=* Aging
* Animals
* Cells, Cultured
* Disease Models, Animal
* Endothelium, Vascular
* Epithelial-Mesenchymal Transition
* Gene Expression Regulation
* Male
* Mice
* Mice, Inbred C57BL
* Mice, Knockout
* RNA, Long Noncoding
* Signal Transduction
* Sirtuins
* Vascular Diseases

|full-text-url=https://sci-hub.do/10.1016/j.ijcard.2019.07.082
}}