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==SIRT1== * {{medline-title |title=Anthocyanins attenuate endothelial dysfunction through regulation of uncoupling of nitric oxide synthase in aged rats. |date=03.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33274583 |full-text-url=https://sci-hub.do/10.1111/acel.13279 }} * {{medline-title |title=Sirtuins and Their Implications in Neurodegenerative Diseases from a Drug Discovery Perspective. |date=05.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33280374 |full-text-url=https://sci-hub.do/10.1021/acschemneuro.0c00696 }} * {{medline-title |title=Effects of alpha-mangostin on memory senescence induced by high glucose in human umbilical vein endothelial cells. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33149857 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585532 }} * {{medline-title |title=[[SIRT1]] Activation Using CRISPR/dCas9 Promotes Regeneration of Human Corneal Endothelial Cells through Inhibiting Senescence. |date=04.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33158256 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694272 }} * {{medline-title |title=Histone Deacetylase [[SIRT1]], Smooth Muscle Cell Function, and Vascular Diseases. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33117155 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573826 }} * {{medline-title |title=6,4'-dihydroxy-7-methoxyflavanone protects against H O -induced cellular senescence by inducing [[SIRT1]] and inhibiting phosphatidylinositol 3-kinase/Akt pathway activation. |date=27.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33111210 |full-text-url=https://sci-hub.do/10.1007/s11010-020-03951-z }} * {{medline-title |title=Isoparvifuran isolated from Dalbergia odorifera attenuates H O -induced senescence of BJ cells through [[SIRT1]] activation and AKT/mTOR pathway inhibition. |date=30.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33010892 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.09.096 }} * {{medline-title |title=[[SIRT1]] Is the Target Gene for 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside Alleviating the HUVEC Senescence. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013385 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508177 }} * {{medline-title |title=The Role of Sirtuins in Kidney Diseases. |date=12.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32932720 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555196 }} * {{medline-title |title=The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32919015 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111090 }} * {{medline-title |title=Virus-Induced Asthma Exacerbations: [[SIRT1]] Targeted Approach. |date=13.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32823491 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464235 }} * {{medline-title |title=Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32793997 |full-text-url=https://sci-hub.do/10.1007/s10522-020-09896-6 }} * {{medline-title |title=Glucose restriction delays senescence and promotes proliferation of HUVECs via the AMPK/[[SIRT1]]-FOXA3-Beclin1 pathway. |date=01.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32768436 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111053 }} * {{medline-title |title=Therapeutic Effects of SRT2104 on Lung Injury in Rats with Emphysema via Reduction of Type II Alveolar Epithelial Cell Senescence. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32722945 |full-text-url=https://sci-hub.do/10.1080/15412555.2020.1797657 }} * {{medline-title |title=Latifolin Inhibits Oxidative Stress-Induced Senescence via Upregulation of [[SIRT1]] in Human Dermal Fibroblasts. |date=01.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32404543 |full-text-url=https://sci-hub.do/10.1248/bpb.b20-00094 }} * {{medline-title |title=SRT1720-induced activation of [[SIRT1]] alleviates vascular smooth muscle cell senescence through PKA-dependent phosphorylation of AMPKα at Ser485. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32421926 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327920 }} * {{medline-title |title=miR-128 plays a critical role in murine osteoclastogenesis and estrogen deficiency-induced bone loss. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32292498 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150474 }} * {{medline-title |title=Lymphocyte senescence in COPD is associated with decreased sirtuin 1 expression in steroid resistant pro-inflammatory lymphocytes. |date=01-12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32270742 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153179 }} * {{medline-title |title=Therapeutic effects of hydro-alcoholic leaf extract of Withania somnifera on age-induced changes in daily rhythms of Sirt1, Nrf2 and Rev-erbα in the SCN of male Wistar rats. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32249404 |full-text-url=https://sci-hub.do/10.1007/s10522-020-09875-x }} * {{medline-title |title=The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32214805 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084123 }} * {{medline-title |title=Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32158519 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048230 }} * {{medline-title |title=Spatiotemporal gating of [[SIRT1]] functions by O-GlcNAcylation is essential for liver metabolic switching and prevents hyperglycemia. |date=24.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32152092 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104039 }} * {{medline-title |title=Hydrogen Sulfide Inhibits Homocysteine-Induced Neuronal Senescence by Up-Regulation of [[SIRT1]]. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32132865 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053352 }} * {{medline-title |title=[[SIRT1]] and aging related signaling pathways. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32084459 |full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111215 }} * {{medline-title |title=Tropisetron protects against brain aging via attenuating oxidative stress, apoptosis and inflammation: The role of [[SIRT1]] signaling. |date=01.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32088214 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.117452 }} * {{medline-title |title=Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of [[SIRT1]] activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32056076 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206476 }} * {{medline-title |title=Deacetylation of MRTF-A by [[SIRT1]] defies senescence induced down-regulation of collagen type I in fibroblast cells. |date=01.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32061777 |full-text-url=https://sci-hub.do/10.1016/j.bbadis.2020.165723 }} * {{medline-title |title=Chronic Polyphenon-60 or Catechin Treatments Increase Brain Monoamines Syntheses and Hippocampal [[SIRT1]] Levels Improving Cognition in Aged Rats. |date=26.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31991916 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071257 }} * {{medline-title |title=Duck Oil-loaded Nanoemulsion Inhibits Senescence of Angiotensin II-treated Vascular Smooth Muscle Cells by Upregulating [[SIRT1]]. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31970335 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957441 }} * {{medline-title |title=Two novel [[SIRT1]] activators, SCIC2 and SCIC2.1, enhance [[SIRT1]]-mediated effects in stress response and senescence. |date=06-07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31942817 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574383 }} * {{medline-title |title=Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1. |date=23.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31881011 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949053 }} * {{medline-title |title=The protective role of omentin-1 in IL-1β-induced chondrocyte senescence. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31852248 |full-text-url=https://sci-hub.do/10.1080/21691401.2019.1699803 }} * {{medline-title |title=The Lifespan Extension Ability of Nicotinic Acid Depends on Whether the Intracellular NAD Level Is Lower than the Sirtuin-Saturating Concentrations. |date=24.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31878234 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982340 }} * {{medline-title |title=Alpha-mangostin decreased cellular senescence in human umbilical vein endothelial cells. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31792920 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214571 }} * {{medline-title |title=Central nervous system [[SIRT1]] expression is required for cued and contextual fear conditioning memory responses in aging mice. |date=23.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31763496 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839599 }} * {{medline-title |title=Does education level protect us from rapid ageing? Sirtuin expression versus age and level of education. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31785216 }} * {{medline-title |title=CO ameliorates endothelial senescence induced by 5-fluorouracil through [[SIRT1]] activation. |date=30.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31704100 |full-text-url=https://sci-hub.do/10.1016/j.abb.2019.108185 }} * {{medline-title |title=Long noncoding RNA GAS5 inhibits cell proliferation and fibrosis in diabetic nephropathy by sponging miR-221 and modulating [[SIRT1]] expression. |date=20.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31631065 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834398 }} * {{medline-title |title=The Role of Sirtuin1 in Regulating Endothelial Function, Arterial Remodeling and Vascular Aging. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31572218 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751260 }} * {{medline-title |title=Deacetylation of LAMP1 drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31544977 |full-text-url=https://sci-hub.do/10.1002/jcp.29182 }} * {{medline-title |title=Plasma exosomes in OSA patients promote endothelial senescence: effect of long-term adherent continuous positive airway pressure. |date=13.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31552414 |full-text-url=https://sci-hub.do/10.1093/sleep/zsz217 }} * {{medline-title |title=Hydrogen Sulfide Inhibits High Glucose-Induced Neuronal Senescence by Improving Autophagic Flux [i]via[/i] Up-regulation of [[SIRT1]]. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31481873 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710442 }} * {{medline-title |title=Activation of the miR-34a-Mediated [[SIRT1]]/mTOR Signaling Pathway by Urolithin A Attenuates D-Galactose-Induced Brain Aging in Mice. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31420820 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985387 }}
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