Редактирование: Публикации о генах и старении (titles) (раздел)

==PTEN==

{{medline-entry
|title=Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33186519


|keywords=* FGF1
* GDF-15
* MMPs
* PTEN
* TIMP1
* docetaxel
* prostate cancer metastasis
* senescence
* senescence-associated secretory phenotype (SASP)
* senolytic therapy
|full-text-url=https://sci-hub.do/10.1016/j.ccell.2020.10.012
}}
{{medline-entry
|title=Alterations in Mitochondrial Dynamic-related Genes in the Peripheral Blood of Alzheimer's Disease Patients.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33023448


|keywords=* Alzheimer's disease
* DRP1
* FIS1
* aging
* mitochondrial dynamics
* mitophagy
|full-text-url=https://sci-hub.do/10.2174/1567205017666201006162538
}}
{{medline-entry
|title=Human ESC-sEVs alleviate age-related bone loss by rejuvenating senescent bone marrow-derived mesenchymal stem cells.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32944188


|keywords=* Extracellular vesicle
* bone loss
* bone marrow MSCs
* cellular senescence
* embryonic stem cells
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480439
}}
{{medline-entry
|title=The precursor of PI(3,4,5)P  alleviates aging by activating daf-18(Pten) and independent of daf-16.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32901024

|mesh-terms=* Aging
* Animals
* Animals, Genetically Modified
* Caenorhabditis elegans
* Caenorhabditis elegans Proteins
* Cell Line, Tumor
* Female
* Forkhead Transcription Factors
* Inositol
* Locomotion
* Longevity
* Metabolic Networks and Pathways
* Metabolomics
* Mice
* Mitophagy
* Models, Animal
* PTEN Phosphohydrolase
* Phosphatidylinositol Phosphates
* Protein Kinases
* Protein-Serine-Threonine Kinases
* RNA Interference
* RNA-Seq

|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479145
}}
{{medline-entry
|title=Quercetin alleviates kidney fibrosis by reducing renal tubular epithelial cell senescence through the SIRT1/PINK1/mitophagy axis.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32702447

|mesh-terms=* Animals
* Antioxidants
* Cell Line
* Cellular Senescence
* Epithelium
* Fibrosis
* Flow Cytometry
* Kidney
* Kidney Tubules, Proximal
* Mitophagy
* Protein Kinases
* Quercetin
* Rats
* Sirtuin 1
|keywords=* Fibrosis
* Mitochondria
* Mitophagy
* Quercetin
* Senescence
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118116
}}
{{medline-entry
|title=Downregulation of [[PTEN]] mediates bleomycin-induced premature senescence in lung cancer cells by suppressing autophagy.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32436415


|keywords=* PI3K/Akt/mTOR pathway
* PTEN
* autophagy
* bleomycin
* cancer cell
* premature senescence
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287201
}}
{{medline-entry
|title=miR-155 inhibits mitophagy through suppression of BAG5, a partner protein of PINK1.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31948758

|mesh-terms=* Adaptor Proteins, Signal Transducing
* Aging
* Animals
* Cell Line
* Cells, Cultured
* Down-Regulation
* Humans
* Male
* Mesenchymal Stem Cells
* Mice, Inbred C57BL
* MicroRNAs
* Mitophagy
* Protein Interaction Maps
* Protein Kinases
* Up-Regulation
|keywords=* Aging
* Bone marrow MSCs
* Mitophagy
* miR-155
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.01.022
}}
{{medline-entry
|title=Environmental Exposures and Asthma Development: Autophagy, Mitophagy, and Cellular Senescence.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31849968

|mesh-terms=* Airway Remodeling
* Asthma
* Autophagy
* Cellular Senescence
* Disease Susceptibility
* Environmental Exposure
* Humans
* Mitophagy
* Oxidative Stress
* Respiratory Mucosa
|keywords=* asthma
* autophagy
* mitophagy
* oxidative stress
* senescence
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896909
}}
{{medline-entry
|title=[[PTEN]] loss regulates alveolar epithelial cell senescence in pulmonary fibrosis depending on Akt activation.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31527305

|mesh-terms=* Aging
* Cellular Senescence
* Epithelial Cells
* Humans
* Idiopathic Pulmonary Fibrosis
* PTEN Phosphohydrolase
* Proto-Oncogene Proteins c-akt
* Pulmonary Alveoli
* Respiratory Mucosa
|keywords=* aging
* cellular senescence
* phosphatase and tension homolog deleted on chromosome ten
* protein kinase B
* pulmonary fibrosis
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781970
}}