Редактирование: Публикации о генах и старении (titles) (раздел)

==ATM==

{{medline-entry
|title=S[[ATM]]F Suppresses the Premature Senescence Phenotype of the [[ATM]] Loss-of-Function Mutant and Improves Its Fertility in [i]Arabidopsis[/i].
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143308


|keywords=* ATM
* DNA damage
* SATMF
* fertility
* leaf senescence
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662627
}}
{{medline-entry
|title=[[ATM]] mediated-p53 signaling pathway forms a novel axis for senescence control.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32949791


|keywords=* ATM inhibition
* Metabolic reprogrammer
* Mitochondria
* P53
* Senescence alleviation
|full-text-url=https://sci-hub.do/10.1016/j.mito.2020.09.002
}}
{{medline-entry
|title=Non-canonical [[ATM]]/MRN activities temporally define the senescence secretory program.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32785991


|keywords=* DNA damage response
* MRN complex
* NF-κB
* chromatin
* senescence secretome
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534619
}}
{{medline-entry
|title=[[ATM]] is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32201398


|keywords=* ATM
* DNA damage response
* NF-κB
* aging
* cellular senescence
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138542
}}
{{medline-entry
|title=[[ATM]] suppresses leaf senescence triggered by DNA double-strand break through epigenetic control of senescence-associated genes in Arabidopsis.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32163596


|keywords=* 
Arabidopsis thaliana

* ATM
* DNA repair
* double-strand breaks
* histone methylation
* leaf senescence
|full-text-url=https://sci-hub.do/10.1111/nph.16535
}}
{{medline-entry
|title=Glioblastoma Cells Do Not Affect Axitinib-Dependent Senescence of HUVECs in a Transwell Coculture Model.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32098270

|mesh-terms=* Ataxia Telangiectasia Mutated Proteins
* Axitinib
* Cell Line, Tumor
* Cellular Senescence
* Coculture Techniques
* Gene Expression Profiling
* Glioblastoma
* Human Umbilical Vein Endothelial Cells
* Humans
* Phosphorylation
|keywords=* Axitinib
* endothelial cells
* glioblastoma
* senescence
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073100
}}
{{medline-entry
|title=Declining BRCA-Mediated DNA Repair in Sperm Aging and its Prevention by Sphingosine-1-Phosphate.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31916095


|keywords=* Aging
* DNA fragmentation
* Gene expression
* Sperm
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065969
}}
{{medline-entry
|title=BRCA-related [[ATM]]-mediated DNA double-strand break repair and ovarian aging.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31822904

|mesh-terms=* Aging
* Animals
* Ataxia Telangiectasia
* BRCA1 Protein
* BRCA2 Protein
* DNA Breaks, Double-Stranded
* DNA Repair
* Female
* Fertility
* Fertility Preservation
* Humans
* Mice
* Oocytes
* Ovarian Follicle
* Ovarian Reserve
* Ovary
|keywords=* 
          BRCA
        
* 
          BRCA1/2
        
* DNA repair
* anti-Mullerian hormone
* chemotherapy
* mutations
* oocyte
* ovarian aging
* ovarian reserve
* ovarian response
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935693
}}
{{medline-entry
|title=[[ATM]] Deficiency Accelerates DNA Damage, Telomere Erosion, and Premature T Cell Aging in HIV-Infected Individuals on Antiretroviral Therapy.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31781094

|mesh-terms=* Anti-Retroviral Agents
* Ataxia Telangiectasia Mutated Proteins
* Cellular Senescence
* DNA Damage
* HIV Infections
* Humans
* T-Lymphocytes
* Telomere
|keywords=* ATM
* DNA damage repair
* HIV
* T cell homeostasis
* apoptosis
* immune aging
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856652
}}
{{medline-entry
|title=SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31565865

|mesh-terms=* Animals
* Ataxia Telangiectasia Mutated Proteins
* Carcinogenesis
* Cells, Cultured
* DNA Damage
* Embryo, Mammalian
* Fibroblasts
* Gamma Rays
* Hematologic Neoplasms
* Heterozygote
* Kaplan-Meier Estimate
* Longevity
* Lymphoma
* Mice, Inbred C57BL
* Mice, Knockout
* Oxidative Stress
* Protein-Serine-Threonine Kinases
|keywords=* DNA damage
* cancer
* inflammation
* lymphoma
* oxidative stress
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850945
}}
{{medline-entry
|title=LncRNA RP11-670E13.6, interacted with hnRNPH, delays cellular senescence by sponging microRNA-663a in UVB damaged dermal fibroblasts.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31444317

|mesh-terms=* Cell Proliferation
* Cellular Senescence
* Fibroblasts
* Heterogeneous-Nuclear Ribonucleoprotein Group F-H
* Humans
* MicroRNAs
* RNA, Long Noncoding
* Skin
* Skin Aging
* Ultraviolet Rays
|keywords=* cellular senescence
* dermal fibroblast
* lncRNA
* microRNA
* ultraviolet B
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738423
}}
{{medline-entry
|title=Tel1/[[ATM]] Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31391264

|mesh-terms=* Amino Acid Substitution
* Ataxia Telangiectasia Mutated Proteins
* Cell Cycle Checkpoints
* Cell Division
* Cellular Senescence
* DNA Damage
* DNA Replication
* DNA, Single-Stranded
* DNA-Binding Proteins
* Intracellular Signaling Peptides and Proteins
* Mutant Proteins
* Protein-Serine-Threonine Kinases
* Saccharomyces cerevisiae
* Saccharomyces cerevisiae Proteins
* Telomerase
* Telomere
* Telomere Shortening
|keywords=* Tel1
* checkpoint
* replicative senescence
* telomere
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781906
}}