Редактирование: Публикации о генах и старении (titles) (раздел)

==PINK1==

{{medline-entry
|title=Spermidine inhibits neurodegeneration and delays aging via the [[PINK1]]-PDR1-dependent mitophagy pathway in [i]C. elegans[/i].
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32902411


|keywords=* aging
* caenorhabditis elegans
* mitophagy
* neurodegenerative diseases
* spermidine
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521492
}}
{{medline-entry
|title=Female mice are resilient to age-related decline of substantia nigra dopamine neuron firing parameters.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32846275


|keywords=* Aging
* Dopamine
* Electrophysiology
* Firing
* Mouse
* Substantia nigra
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606778
}}
{{medline-entry
|title=Attenuation of epigenetic regulator SMARCA4 and ERK-ETS signaling suppresses aging-related dopaminergic degeneration.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32749068


|keywords=* 
Drosophila

* MAPK-ERK-ETS signaling
* Parkinson's disease
* SMARCA4/Brahma
* aging
* neurodegeneration
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511865
}}
{{medline-entry
|title=SIRT1 alleviates high-magnitude compression-induced senescence in nucleus pulposus cells via [[PINK1]]-dependent mitophagy.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32687063


|keywords=* SIRT1
* compression
* mitophagy
* nucleus pulposus
* senescence
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485741
}}
{{medline-entry
|title=Synergistic action of propolis with levodopa in the management of Parkinsonism in Drosophila melanogaster.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32386191


|keywords=* Drosophila melanogaster
* Levodopa induced dyskinesia
* PINK1B9

* Parkinsonism
* Parkinson’s disease
* aging
* antioxidant activity
* catalase
* climbing index
* lifespan
* oxidative stress
* propolis
|full-text-url=https://sci-hub.do/10.1515/jcim-2019-0136
}}
{{medline-entry
|title=Compression-induced senescence of nucleus pulposus cells by promoting mitophagy activation via the [[PINK1]]/PARKIN pathway.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32281308


|keywords=* PARKIN pathway
* PINK1
* compression
* intervertebral disc
* mitophagy
* senescence
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214186
}}
{{medline-entry
|title=Doxorubicin-induced normal breast epithelial cellular aging and its related breast cancer growth through mitochondrial autophagy and oxidative stress mitigated by ginsenoside Rh2.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32100342

|mesh-terms=* Autophagy
* Breast Neoplasms
* Cell Culture Techniques
* Cell Line, Tumor
* Doxorubicin
* Drugs, Chinese Herbal
* Female
* Ginsenosides
* Humans
* Mitochondria
* Oxidative Stress
|keywords=* ROS
* cancer growth
* cellular senescence
* chemotherapy
* ginsenoside Rh2
* mitophagy
|full-text-url=https://sci-hub.do/10.1002/ptr.6636
}}
{{medline-entry
|title=Mitochondrial DNA heteroplasmy rises in substantial nigra of aged [[PINK1]] KO mice.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31727366

|mesh-terms=* Aging
* Animals
* Brain
* DNA Copy Number Variations
* DNA, Mitochondrial
* Gene Frequency
* Mice, Knockout
* Mutation Rate
* Protein Kinases
* Substantia Nigra
|keywords=* PINK1
* Parkin
* Parkinson’s disease
* mtDNA heteroplasmy
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.10.112
}}