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Aging genes 30-59
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==FOXO3== * {{medline-title |title=The DNA methylation of [[FOXO3]] and TP53 as a blood biomarker of late-onset asthma. |date=09.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33298101 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726856 }} * {{medline-title |title=[[FOXO3]] targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16 increase. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33156570 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681055 }} * {{medline-title |title=Astaxanthin as a Putative Geroprotector: Molecular Basis and Focus on Brain Aging. |date=05.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32635607 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401246 }} * {{medline-title |title=Inflamma-miR-21 Negatively Regulates Myogenesis during Ageing. |date=23.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32340146 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222422 }} * {{medline-title |title=Variable DNA methylation of aging-related genes is associated with male COPD. |date=04.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31684967 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829949 }} * {{medline-title |title=A conserved role of the insulin-like signaling pathway in diet-dependent uric acid pathologies in Drosophila melanogaster. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31415568 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695094 }} * {{medline-title |title=[[FOXO3]] on the Road to Longevity: Lessons From SNPs and Chromatin Hubs. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31303978 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606898 }} * {{medline-title |title=Longevity-Associated Forkhead Box O3 ([[FOXO3]]) Single Nucleotide Polymorphisms are Associated with Type 2 Diabetes Mellitus in Chinese Elderly Women. |date=22.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31009445 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489531 }} * {{medline-title |title=Signal Transduction, Ageing and Disease. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30888655 |full-text-url=https://sci-hub.do/10.1007/978-981-13-3681-2_9 }} * {{medline-title |title=[[FOXO3]], a Molecular Search for the Fountain of Youth. |date=07.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30849363 |full-text-url=https://sci-hub.do/10.1016/j.stem.2019.02.008 }} * {{medline-title |title=10-year follow-up of the Super-Seniors Study: compression of morbidity and genetic factors. |date=28.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30819100 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394013 }} * {{medline-title |title=Taste receptors, innate immunity and longevity: the case of [[TAS2R16]] gene. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30833980 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387736 }} * {{medline-title |title=[[FOXO3]]-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration. |date=07.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661960 |full-text-url=https://sci-hub.do/10.1016/j.stem.2018.12.002 }} * {{medline-title |title=Analysis of [[FOXO3]] Gene Polymorphisms Associated with Human Longevity. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30414160 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334034 }} * {{medline-title |title=Recent advances in understanding the role of [[FOXO3]]. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228872 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124385 }} * {{medline-title |title=FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29963746 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156454 }} * {{medline-title |title=The longevity SNP rs2802292 uncovered: [[HSF1]] activates stress-dependent expression of [[FOXO3]] through an intronic enhancer. |date=20.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733381 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009585 }} * {{medline-title |title=Minimal Shortening of Leukocyte Telomere Length Across Age Groups in a Cross-Sectional Study for Carriers of a Longevity-Associated [[FOXO3]] Allele. |date=08.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29688278 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175018 }} * {{medline-title |title=FOXO in Neural Cells and Diseases of the Nervous System. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29433734 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881381 }} * {{medline-title |title=Genetic Variation in [[FOXO3]] is Associated with Self-Rated Health in a Population-Based Sample of Older Individuals. |date=08.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415201 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175024 }} * {{medline-title |title=Identification and characterization of two functional variants in the human longevity gene [[FOXO3]]. |date=12.12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234056 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727304 }} * {{medline-title |title=Effects of [[FOXO3]] Polymorphisms on Survival to Extreme Longevity in Four Centenarian Studies. |date=08.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28977569 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175020 }} * {{medline-title |title=FOXO Transcriptional Factors and Long-Term Living. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28894507 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574317 }} * {{medline-title |title=[[FOXO3]] longevity interactome on chromosome 6. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28722347 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595686 }} * {{medline-title |title=The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington's disease. |date=21.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28638078 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479833 }} * {{medline-title |title=Age-related reduction in the expression of FOXO transcription factors and correlations with intervertebral disc degeneration. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28430387 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650945 }} * {{medline-title |title=[[FOXO3]] Transcription Factor Is Essential for Protecting Hematopoietic Stem and Progenitor Cells from Oxidative DNA Damage. |date=17.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27994057 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314194 }} * {{medline-title |title=Modulation of gut microbiota and delayed immunosenescence as a result of syringaresinol consumption in middle-aged mice. |date=15.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27976725 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157019 }} * {{medline-title |title=Genetic Association Analysis of Common Variants in [[FOXO3]] Related to Longevity in a Chinese Population. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27936216 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148017 }} * {{medline-title |title=Genome-wide Association Study of Parental Life Span. |date=01.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27816938 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861941 }} * {{medline-title |title=Longevity-Associated [[FOXO3]] Genotype and its Impact on Coronary Artery Disease Mortality in Japanese, Whites, and Blacks: A Prospective Study of Three American Populations. |date=01.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27694344 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964743 }} * {{medline-title |title=Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27329260 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013013 }} * {{medline-title |title=Diabetic complications within the context of aging: Nicotinamide adenine dinucleotide redox, insulin C-peptide, sirtuin 1-liver kinase B1-adenosine monophosphate-activated protein kinase positive feedback and forkhead box O3. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27181414 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931191 }} * {{medline-title |title=The FoxO3 gene and cause-specific mortality. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27071935 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933667 }} * {{medline-title |title=Association study of polymorphisms in [[FOXO3]], [[AKT1]] and IGF-2R genes with human longevity in a Han Chinese population. |date=05.01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26683100 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807980 }} * {{medline-title |title=Genetic factors and epigenetic mechanisms of longevity: current perspectives. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26639084 |full-text-url=https://sci-hub.do/10.2217/epi.15.80 }} * {{medline-title |title=Long live FOXO: unraveling the role of FOXO proteins in aging and longevity. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26643314 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783344 }} * {{medline-title |title=Association Analysis of [[FOXO3]] Longevity Variants With Blood Pressure and Essential Hypertension. |date=01.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26476085 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055732 }} * {{medline-title |title=Mitochondrial metabolism in hematopoietic stem cells requires functional [[FOXO3]]. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26209246 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576984 }} * {{medline-title |title=The MicroRNA-132 and MicroRNA-212 Cluster Regulates Hematopoietic Stem Cell Maintenance and Survival with Age by Buffering [[FOXO3]] Expression. |date=16.06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26084022 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471877 }} * {{medline-title |title=Age-Based Differences in the Genetic Determinants of Glycemic Control: A Case of [[FOXO3]] Variations. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25993007 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439071 }} * {{medline-title |title=Tocotrienol-rich fraction prevents cellular aging by modulating cell proliferation signaling pathways. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25945449 |full-text-url=https://sci-hub.do/10.7417/CT.2015.1825 }} * {{medline-title |title=[[FOXO3]] variants are beneficial for longevity in Southern Chinese living in the Red River Basin: A case-control study and meta-analysis. |date=27.04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25913413 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386198 }} * {{medline-title |title=[[FOXO3]]: A Major Gene for Human Longevity--A Mini-Review. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25832544 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403515 }} * {{medline-title |title=Senescence of human skin-derived precursors regulated by Akt-[[FOXO3]]-p27(KIP¹)/p15(INK⁴b) signaling. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25753771 |full-text-url=https://sci-hub.do/10.1007/s00018-015-1877-3 }} * {{medline-title |title=SIRT6 minor allele genotype is associated with >5-year decrease in lifespan in an aged cohort. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25541994 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277407 }} * {{medline-title |title=Association of the insulin-like growth factor binding protein 3 (IGFBP-3) polymorphism with longevity in Chinese nonagenarians and centenarians. |date=11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25553725 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276788 }} * {{medline-title |title=E2F transcription factor 1 regulates cellular and organismal senescence by inhibiting Forkhead box O transcription factors. |date=05.12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25344604 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256352 }} * {{medline-title |title=GxE interactions between FOXO genotypes and drinking tea are significantly associated with prevention of cognitive decline in advanced age in China. |date=04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24895270 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447795 }} * {{medline-title |title=Shorter men live longer: association of height with longevity and [[FOXO3]] genotype in American men of Japanese ancestry. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24804734 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013008 }} * {{medline-title |title=[[FOXO3]] and related transcription factors in development, aging, and exceptional longevity. |date=04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24747665 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447793 }}
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