Редактирование: Публикации о генах и старении (titles) (раздел)

==NLRP3==

{{medline-entry
|title=Innate and Adaptive Immunity in Aging and Longevity: The Foundation of Resilience.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33269094


|keywords=* adaptive immunity
* aging
* innate immunity
* longevity
* resilience
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673842
}}
{{medline-entry
|title=TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33113366


|keywords=* CHIP
* IL-1β
* TET2
* adipose tissue
* aging
* clonal hematopoiesis
* diabetes
* insulin resistance
* obesity
* somatic mutations
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2020.108326
}}
{{medline-entry
|title=Repeated propofol exposure-induced neuronal damage and cognitive impairment in aged rats by activation of NF-κB pathway and [[NLRP3]] inflammasome.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33115643


|keywords=* Aging
* Apoptosis
* NOD-like receptor protein 3 inflammasome
* Neuroinflammation
* Postoperative cognitive dysfunction
* Propofol
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2020.135461
}}
{{medline-entry
|title=A Small Molecule Stabilizer of the MYC G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066043


|keywords=* ASC and pannexin 1
* MYC G4-quadruplex stabilizer
* NLRP3
* caspase 1
* endoplasmic reticulum stress
* gasdermin D
* inflammasome
* pyroptosis
* senescence
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650714
}}
{{medline-entry
|title=Interleukin-1β Drives Cellular Senescence of Rat Astrocytes Induced by Oligomerized Amyloid β Peptide and Oxidative Stress.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013631


|keywords=* Alzheimer's disease
* amyloid β
* astrocyte
* interleukin-1β
* neuroinflammation
* senescence
* tau
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493674
}}
{{medline-entry
|title=Mechanisms of [[NLRP3]] priming in inflammaging and age related diseases.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32883606


|keywords=* Aging
* Inflammaging
* Inflammasome
* NLRP3
* Priming
* Senescence
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571497
}}
{{medline-entry
|title=Lamivudine Inhibits [i]Alu[/i] RNA-induced Retinal Pigment Epithelium Degeneration via Anti-inflammatory and Anti-senescence Activities.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32855848


|keywords=* NLRP3 inflammasome
* age-related macular degeneration
* lamivudine
* retinal pigment epithelium
* senescence
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422901
}}
{{medline-entry
|title=The [[NLRP3]] Inflammasome: Metabolic Regulation and Contribution to Inflammaging.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32751530


|keywords=* NLRP3 inflammasome
* aging
* inflammation
* metabolism
* mitochondria
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463618
}}
{{medline-entry
|title=Aging aggravated liver ischemia and reperfusion injury by promoting STING-mediated [[NLRP3]] activation in macrophages.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32666684


|keywords=* aging
* and reperfusion injury
* leucine-rich repeat containing protein 3
* liver ischemia
* macrophage immune response
* nucleotide-binding domain
* stimulator of interferon genes
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431827
}}
{{medline-entry
|title=Targeting [[NLRP3]] Inflammasome Reduces Age-Related Experimental Alveolar Bone Loss.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32531176


|keywords=* aging
* inflammasomes
* inflammation
* macrophages
* osteoclasts
* periodontitis
|full-text-url=https://sci-hub.do/10.1177/0022034520933533
}}
{{medline-entry
|title=Korean Red Ginseng Suppresses the Expression of Oxidative Stress Response and [[NLRP3]] Inflammasome Genes in Aged C57BL/6 Mouse Ovaries.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32331214


|keywords=* Korean ginseng extract
* NLRP3 inflammasome
* aging
* ovary
* oxidative stress response
* subfertility
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231237
}}
{{medline-entry
|title=Cepharanthine promotes the effect of dexmedetomidine on the deposition of β-amyloid in the old age of the senile dementia rat model by regulating inflammasome expression.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32337948

|mesh-terms=* Aging
* Animals
* Benzylisoquinolines
* Brain
* Dexmedetomidine
* Inflammasomes
* Inflammation
* Male
* Mitochondria
* Oxidative Stress
* Rats, Sprague-Dawley
* Reactive Oxygen Species
|keywords=*  dementia
*  dexmedetomidine
*  inflammasomes
*  β-amyloid
* cepharanthine
|full-text-url=https://sci-hub.do/10.5114/fn.2019.89855
}}
{{medline-entry
|title=Ginsenoside Rg1 ameliorates glomerular fibrosis during kidney aging by inhibiting NOX4 and [[NLRP3]] inflammasome activation in SAMP8 mice.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32114413


|keywords=* Ginsenoside Rg1
* Kidney aging
* NADPH oxidase 4 (NOX4)
* NLRP3 inflammasome
* Renal fibrosis
|full-text-url=https://sci-hub.do/10.1016/j.intimp.2020.106339
}}
{{medline-entry
|title=Blockade of the [[NLRP3]] inflammasome improves metabolic health and lifespan in obese mice.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31975052


|keywords=* Aging
* Autophagy
* High-fat diet
* Longevity
* NLRP3 inflammasome
* Obesity
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206474
}}
{{medline-entry
|title=Autophagy and [[NLRP3]] inflammasome crosstalk in neuroinflammation in aged bovine brains.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31903559


|keywords=* NLRP3 inflammasome
* aging
* autophagy
* bovine
* immunosenescence
* neuroinflammation
|full-text-url=https://sci-hub.do/10.1002/jcp.29426
}}
{{medline-entry
|title=[[NLRP3]] Inflammasome Inhibition by MCC950 in Aged Mice Improves Health via Enhanced Autophagy and PPARα Activity.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31603987


|keywords=* Aging
* Autophagy
* MCC950
* NLRP3 inflammasome
* PPARα
|full-text-url=https://sci-hub.do/10.1093/gerona/glz239
}}
{{medline-entry
|title=[[NLRP3]] inflammasome suppression improves longevity and prevents cardiac aging in male mice.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31625260


|keywords=* NLRP3-inflammasome
* autophagy
* cardiac aging
* longevity
* morbidity
* mortality
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974709
}}
{{medline-entry
|title=Reduced NRF2 expression suppresses endothelial progenitor cell function and induces senescence during aging.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31494646

|mesh-terms=* Aging
* Animals
* Cellular Senescence
* Endothelial Progenitor Cells
* Mice
* NF-E2-Related Factor 2
* NF-kappa B
* NLR Family, Pyrin Domain-Containing 3 Protein
* Neovascularization, Physiologic
* Oxidative Stress
|keywords=* NLRP3 inflammasome
* NRF2
* aging
* endothelial progenitor cells
* oxidative stress
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756903
}}
{{medline-entry
|title=Effect of Aging on Taurine Transporter (TauT) Expression in the Mouse Brain Cortex.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31468381

|mesh-terms=* Aging
* Animals
* Brain
* Membrane Glycoproteins
* Membrane Transport Proteins
* Mice
* Mice, Inbred C57BL
* Taurine
|keywords=* Age-related diseases
* Glycine Transporter (GLYT)
* NLRP3
* Taurine Transporter (TauT)
|full-text-url=https://sci-hub.do/10.1007/978-981-13-8023-5_1
}}