Редактирование: Aging genes 100-199 (раздел)

==CA3==

* {{medline-title
|title=Memory and dendritic spines loss, and dynamic dendritic spines changes are age-dependent in the rat.
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32950615
|full-text-url=https://sci-hub.do/10.1016/j.jchemneu.2020.101858
}}
* {{medline-title
|title=Changes of fat-mass and obesity-associated protein expression in the hippocampus in animal models of high-fat diet-induced obesity and D-galactose-induced aging.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32647628
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336480
}}
* {{medline-title
|title=Features of Postnatal Hippocampal Development in a Rat Model of Sporadic Alzheimer's Disease.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32581685
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289999
}}
* {{medline-title
|title=Heterogeneity in brain distribution of activated microglia and astrocytes in a rat ischemic model of Alzheimer's disease after 2 years of survival.
|date=05.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32501292
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343500
}}
* {{medline-title
|title=Maintaining Aging Hippocampal Function with Safe and Feasible Shaking Exercise in SAMP10 Mice.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32526748
|full-text-url=https://sci-hub.do/10.1159/000507884
}}
* {{medline-title
|title=Associations between pattern separation and hippocampal subfield structure and function vary along the lifespan: A 7 T imaging study.
|date=05.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32371923
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200747
}}
* {{medline-title
|title=Age-Related Changes in Synaptic Plasticity Associated with Mossy Fiber Terminal Integration during Adult Neurogenesis.
|date=05-06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32332082
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240290
}}
* {{medline-title
|title=Functional Connectivity of Hippocampal [[CA3]] Predicts Neurocognitive Aging via [[CA1]]-Frontal Circuit.
|date=30.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32239141
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325802
}}
* {{medline-title
|title=Metabotropic Glutamate Receptors at the Aged Mossy Fiber - [[CA3]] Synapse of the Hippocampus.
|date=07.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31917351
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2019.12.016
}}
* {{medline-title
|title=Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-[[CA3]] synapses.
|date=23.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31873156
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927957
}}
* {{medline-title
|title=PACAP27 mitigates an age-dependent hippocampal vulnerability to PGJ2-induced spatial learning deficits and neuroinflammation in mice.
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31769222
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955932
}}
* {{medline-title
|title=GABA  Receptors Are Well Preserved in the Hippocampus of Aged Mice.
|date=07-08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31340951
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709233
}}
* {{medline-title
|title=Cellular and Molecular Differences Between Area [[CA1]] and the Dentate Gyrus of the Hippocampus.
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30874972
|full-text-url=https://sci-hub.do/10.1007/s12035-019-1541-2
}}
* {{medline-title
|title=Establishment of Novel Murine Model showing Vascular Inflammation-derived Cognitive Dysfunction.
|date=11.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30858535
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411753
}}
* {{medline-title
|title=p16  deletion in cells of the intervertebral disc affects their matrix homeostasis and senescence associated secretory phenotype without altering onset of senescence.
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30811968
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708504
}}
* {{medline-title
|title=Cyclohexane Inhalation Produces Long-Lasting Alterations in the Hippocampal Integrity and Reward-Seeking Behavior in the Adult Mouse.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30771197
|full-text-url=https://sci-hub.do/10.1007/s10571-019-00660-0
}}
* {{medline-title
|title=Experience-Dependent Effects of Muscimol-Induced Hippocampal Excitation on Mnemonic Discrimination.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30687032
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335355
}}
* {{medline-title
|title=Astrocytic changes with aging and Alzheimer's disease-type pathology in chimpanzees.
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30578640
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401278
}}
* {{medline-title
|title=Melatonin Influences Structural Plasticity in the Axons of Granule Cells in the Dentate Gyrus of Balb/C Mice.
|date=25.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585191
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337618
}}
* {{medline-title
|title=Alzheimer's Disease Biomarkers Have Distinct Associations with Specific Hippocampal Subfield Volumes.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320590
|full-text-url=https://sci-hub.do/10.3233/JAD-180676
}}
* {{medline-title
|title=Early disruption of parvalbumin expression and perineuronal nets in the hippocampus of the Tg2576 mouse model of Alzheimer's disease can be rescued by enriched environment.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30273829
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.08.024
}}
* {{medline-title
|title=Susceptibility to hippocampal kindling seizures is increased in aging C57 black mice.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30135940
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084868
}}
* {{medline-title
|title=[AGE-RELATED CHANGES IN THE MORPHOMETRIC PARAMETERS OF THE NEURONS IN HUMAN HIPPOCAMPUS].
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30136816

}}
* {{medline-title
|title=Microglia changes associated to Alzheimer's disease pathology in aged chimpanzees.
|date=15.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30069930
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283685
}}
* {{medline-title
|title=Premarin has opposing effects on spatial learning, neural activation, and serum cytokine levels in middle-aged female rats depending on reproductive history.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30056312
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.06.030
}}
* {{medline-title
|title=Nonsteroidal anti-inflammatory drug, indomethacin improves spatial memory and NMDA receptor function in aged animals.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30031231
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119103
}}
* {{medline-title
|title=Biospectroscopic Imaging Provides Evidence of Hippocampal Zn Deficiency and Decreased Lipid Unsaturation in an Accelerated Aging Mouse Model.
|date=21.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29901988
|full-text-url=https://sci-hub.do/10.1021/acschemneuro.8b00193
}}
* {{medline-title
|title=Trimethylamine-N-oxide promotes brain aging and cognitive impairment in mice.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29749694
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052480
}}
* {{medline-title
|title=Dynamic SAP102 expression in the hippocampal subregions of rats and APP/PS1 mice of various ages.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29574717
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979819
}}
* {{medline-title
|title=Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29529016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893385
}}
* {{medline-title
|title=Stereological Analysis of Microglia in Aged Male and Female Fischer 344 Rats in Socially Relevant Brain Regions.
|date=01.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29496632
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882587
}}
* {{medline-title
|title=GPR30 activation improves memory and facilitates DHPG-induced LTD in the hippocampal [[CA3]] of middle-aged mice.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29421611
|full-text-url=https://sci-hub.do/10.1016/j.nlm.2018.02.005
}}
* {{medline-title
|title=Neurodevelopment and behavior in neonatal OXYS rats with genetically determined accelerated senescence.
|date=15.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29274882
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2017.12.021
}}
* {{medline-title
|title=Hippocampal Transcriptomic Profiles: Subfield Vulnerability to Age and Cognitive Impairment.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29276487
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727020
}}
* {{medline-title
|title=Excitatory Synaptic Input to Hilar Mossy Cells under Basal and Hyperexcitable Conditions.
|date=11-12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29214210
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714709
}}
* {{medline-title
|title=Age-related vulnerability of pattern separation in C57BL/6J mice.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29149630
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.10.013
}}
* {{medline-title
|title=Age-related epigenetic changes in hippocampal subregions of four animal models of Alzheimer's disease.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29113959
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863355
}}
* {{medline-title
|title=Time of day but not aging regulates 5-HT  receptor binding sites in the hamster hippocampus.
|date=01.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29107707
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2017.10.057
}}
* {{medline-title
|title=Cytoarchitectonically-driven MRI atlas of nonhuman primate hippocampus: Preservation of subfield volumes in aging.
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29072793
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920786
}}
* {{medline-title
|title=The impact of ageing reveals distinct roles for human dentate gyrus and [[CA3]] in pattern separation and object recognition memory.
|date=25.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29070813
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656671
}}
* {{medline-title
|title=Age-dependent differences in myelin basic protein expression in the hippocampus of young, adult and aged gerbils.
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29046699
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645602
}}
* {{medline-title
|title=Dopamine D4 receptor activation restores [[CA1]] LTP in hippocampal slices from aged mice.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28975698
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676052
}}
* {{medline-title
|title=Gpr158 mediates osteocalcin's regulation of cognition.
|date=02.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28851741
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626410
}}
* {{medline-title
|title=Critical periods regulating the circuit integration of adult-born hippocampal neurons.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28828636
|full-text-url=https://sci-hub.do/10.1007/s00441-017-2677-x
}}
* {{medline-title
|title=Attenuated Activity across Multiple Cell Types and Reduced Monosynaptic Connectivity in the Aged Perirhinal Cortex.
|date=13.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28821661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597979
}}
* {{medline-title
|title=Distribution of corticotropin-releasing factor receptor 1 in the developing mouse forebrain: A novel sex difference revealed in the rostral periventricular hypothalamus.
|date=11.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28823817
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173945
}}
* {{medline-title
|title=Age-related deficits in the mnemonic similarity task for objects and scenes.
|date=30.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28673769
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760178
}}
* {{medline-title
|title=Age-dependent changes in autophosphorylation of alpha calcium/calmodulin dependent kinase II in hippocampus and amygdala after contextual fear conditioning.
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28648815
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599619
}}
* {{medline-title
|title=Apoptosis Following Cortical Spreading Depression in Juvenile Rats.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28612259
|full-text-url=https://sci-hub.do/10.1007/s12035-017-0642-z
}}
* {{medline-title
|title=The AMPA receptor positive allosteric modulator S 47445 rescues in vivo [[CA3]]-[[CA1]] long-term potentiation and structural synaptic changes in old mice.
|date=01.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28603025
|full-text-url=https://sci-hub.do/10.1016/j.neuropharm.2017.06.009
}}
* {{medline-title
|title=The aminoestrogen prolame increases recognition memory and hippocampal neuronal spine density in aged mice.
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28545157
|full-text-url=https://sci-hub.do/10.1002/syn.21987
}}
* {{medline-title
|title=Targeting Adult Neurogenesis to Optimize Hippocampal Circuits in Aging.
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28536851
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509633
}}
* {{medline-title
|title=[Effects of recombinant human erythropoietin on brain-derived neurotrophic factor expression in different brain regions of aging rats].
|date=20.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28446413
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744085
}}
* {{medline-title
|title=[COMPARATIVE MORPHOFUNCTIONAL CHARACTERISTICS OF ADULT AND OLD RAT VENTRAL HIPPOCAMPUS TO COMBINED STRESS INFLUENCE].
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28423247

}}
* {{medline-title
|title=Comparison of the influence of two models of mild stress on hippocampal brain-derived neurotrophin factor ([[BDNF]]) immunoreactivity in old age rats.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28379217
|full-text-url=https://sci-hub.do/10.21307/ane-2017-037
}}
* {{medline-title
|title=Rodent age-related impairments in discriminating perceptually similar objects parallel those observed in humans.
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28342259
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479708
}}
* {{medline-title
|title=Protective effect of a phenolic extract containing indoline amides from Portulaca oleracea against cognitive impairment in senescent mice induced by large dose of D-galactose /NaNO .
|date=05.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28363525
|full-text-url=https://sci-hub.do/10.1016/j.jep.2017.03.050
}}
* {{medline-title
|title=Hippocampal [[CA3]]-dentate gyrus volume uniquely linked to improvement in associative memory from childhood to adulthood.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28342999
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477670
}}
* {{medline-title
|title=Rapid and stable changes in maturation-related phenotypes of the adult hippocampal neurons by electroconvulsive treatment.
|date=02.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28253930
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335812
}}
* {{medline-title
|title=Age and Environment Influences on Mouse Prion Disease Progression: Behavioral Changes and Morphometry and Stereology of Hippocampal Astrocytes.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28243355
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294381
}}
* {{medline-title
|title=Requiring collaboration: Hippocampal-prefrontal networks needed in spatial working memory and ageing. A multivariate analysis approach.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28213065
|full-text-url=https://sci-hub.do/10.1016/j.nlm.2017.02.008
}}
* {{medline-title
|title=Running-induced memory enhancement correlates with the preservation of thin spines in the hippocampal area [[CA1]] of old C57BL/6 mice.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28157554
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.01.002
}}
* {{medline-title
|title=Heightened cortical excitability in aged rodents with memory impairment.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28104309
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401793
}}
* {{medline-title
|title=Curcuma treatment prevents cognitive deficit and alteration of neuronal morphology in the limbic system of aging rats.
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27997735
|full-text-url=https://sci-hub.do/10.1002/syn.21952
}}
* {{medline-title
|title=Mid-life environmental enrichment increases synaptic density in [[CA1]] in a mouse model of Aβ-associated pathology and positively influences synaptic and cognitive health in healthy ageing.
|date=01.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27987205
|full-text-url=https://sci-hub.do/10.1002/cne.24156
}}
* {{medline-title
|title=Chronic Progressive Neurodegeneration in a Transgenic Mouse Model of Prion Disease.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27891071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104746
}}
* {{medline-title
|title=Protective effects of high Tryptophan diet on aging-induced passive avoidance impairment and hippocampal apoptosis.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27889579
|full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2016.11.007
}}
* {{medline-title
|title=Postnatal irradiation-induced hippocampal neuropathology, cognitive impairment and aging.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27876394
|full-text-url=https://sci-hub.do/10.1016/j.braindev.2016.11.001
}}
* {{medline-title
|title=PGE -EP3 signaling pathway impairs hippocampal presynaptic long-term plasticity in a mouse model of Alzheimer's disease.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27837675
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2016.10.012
}}
* {{medline-title
|title=Ontogeny of Norepinephrine Transporter Expression and Antidepressant-Like Response to Desipramine in Wild-Type and Serotonin Transporter Mutant Mice.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27831486
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193070
}}
* {{medline-title
|title=Aging-related impairments of hippocampal mossy fibers synapses on [[CA3]] pyramidal cells.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27794263
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2016.09.010
}}
* {{medline-title
|title=Epigenetic regulation of estrogen receptor α contributes to age-related differences in transcription across the hippocampal regions [[CA1]] and [[CA3]].
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27776265
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479492
}}
* {{medline-title
|title=Reduction of dynamin 1 in the hippocampus of aged mice is associated with the decline in hippocampal‑dependent memory.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27748822
|full-text-url=https://sci-hub.do/10.3892/mmr.2016.5804
}}
* {{medline-title
|title=Roles of hippocampal subfields in verbal and visual episodic memory.
|date=15.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27646772
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343125
}}
* {{medline-title
|title=Suppressor of Cytokine Signalling 2 ([[SOCS2]]) Regulates Numbers of Mature Newborn Adult Hippocampal Neurons and Their Dendritic Spine Maturation.
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27655030
|full-text-url=https://sci-hub.do/10.1007/s10571-016-0427-3
}}
* {{medline-title
|title=Age dependent neuroprotective effects of medhya rasayana prepared from Clitoria ternatea Linn. in stress induced rat brain.
|date=02.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27469198
|full-text-url=https://sci-hub.do/10.1016/j.jep.2016.07.068
}}
* {{medline-title
|title=The neuron-astrocyte-microglia triad involvement in neuroinflammaging mechanisms in the [[CA3]] hippocampus of memory-impaired aged rats.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27466072
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.07.011
}}
* {{medline-title
|title=Intrinsic Hippocampal Excitability Changes of Opposite Signs and Different Origins in [[CA1]] and [[CA3]] Pyramidal Neurons Underlie Aging-Related Cognitive Deficits.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27375440
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899460
}}
* {{medline-title
|title=Glycogen distribution in the microwave-fixed mouse brain reveals heterogeneous astrocytic patterns.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27353480
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094520
}}
* {{medline-title
|title=Type 3 Adenylyl Cyclase and Somatostatin Receptor 3 Expression Persists in Aged Rat Neocortical and Hippocampal Neuronal Cilia.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27303293
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885836
}}
* {{medline-title
|title=Global hypoxia induced impairment in learning and spatial memory is associated with precocious hippocampal aging.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27246251
|full-text-url=https://sci-hub.do/10.1016/j.nlm.2016.05.011
}}
* {{medline-title
|title=Enhanced Cognition and Hypoglutamatergic Signaling in a Growth Hormone Receptor Knockout Mouse Model of Successful Aging.
|date=01.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27208894
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410893
}}
* {{medline-title
|title=Developmental Age Differentially Mediates the Calcium-Binding Protein Parvalbumin in the Rat: Evidence for a Selective Decrease in Hippocampal Parvalbumin Cell Counts.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27002731
|full-text-url=https://sci-hub.do/10.1159/000444447
}}
* {{medline-title
|title=Chronic administration of resveratrol prevents morphological changes in prefrontal cortex and hippocampus of aged rats.
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26789275
|full-text-url=https://sci-hub.do/10.1002/syn.21888
}}
* {{medline-title
|title=Music exposure improves spatial cognition by enhancing the [[BDNF]] level of dorsal hippocampal subregions in the developing rats.
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26802511
|full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2016.01.009
}}
* {{medline-title
|title=Thrombin modulates persistent sodium current in [[CA1]] pyramidal neurons of young and adult rat hippocampus.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26552299
|full-text-url=https://sci-hub.do/10.15407/fz61.04.005
}}
* {{medline-title
|title=Effects of Ginkgo biloba extract on the structure of Cornu Ammonis in aged rat: A morphometric study.
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26523225
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620195
}}
* {{medline-title
|title=Memory impairment in aged primates is associated with region-specific network dysfunction.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26503764
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848213
}}
* {{medline-title
|title=Cognitive and behavior deficits in sickle cell mice are associated with profound neuropathologic changes in hippocampus and cerebellum.
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26462816
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688201
}}
* {{medline-title
|title=Changes in serotonin (5-HT) and brain-derived neurotrophic factor (BDFN) expression in frontal cortex and hippocampus of aged rat treated with high tryptophan diet.
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26444078
|full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2015.09.010
}}
* {{medline-title
|title=[MORPHOLOGICAL CHARACTERIZATION OF OXYS AND WISTAR RAT HIPPOCAMPUS IN THE AGING PROCESS].
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26390540

}}
* {{medline-title
|title=Complement [[C3]]-Deficient Mice Fail to Display Age-Related Hippocampal Decline.
|date=23.09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26400934
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605437
}}
* {{medline-title
|title=Aging-Related Hyperexcitability in [[CA3]] Pyramidal Neurons Is Mediated by Enhanced A-Type K  Channel Function and Expression.
|date=23.09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26400949
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579378
}}
* {{medline-title
|title=Hippocampal cytogenesis and spatial learning in senile rats exposed to chronic variable stress: effects of previous early life exposure to mild stress.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26347648
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539520
}}
* {{medline-title
|title=Age-dependent loss of parvalbumin-expressing hippocampal interneurons in mice deficient in [[CHL1]], a mental retardation and schizophrenia susceptibility gene.
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26285062
|full-text-url=https://sci-hub.do/10.1111/jnc.13284
}}
* {{medline-title
|title=Age differences in hippocampal subfield volumes from childhood to late adulthood.
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26286891
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718822
}}
* {{medline-title
|title=Development of Adult-Generated Cell Connectivity with Excitatory and Inhibitory Cell Populations in the Hippocampus.
|date=22.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26203153
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605118
}}
* {{medline-title
|title=Nicotine Administration Attenuates Methamphetamine-Induced Novel Object Recognition Deficits.
|date=11.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26164716
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675982
}}
* {{medline-title
|title=Pathological changes in hippocampal neuronal circuits underlie age-associated neurodegeneration and memory loss: positive clue toward SAD.
|date=20.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26045180
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2015.05.062
}}
* {{medline-title
|title=Combined administration of levetiracetam and valproic acid attenuates age-related hyperactivity of [[CA3]] place cells, reduces place field area, and increases spatial information content in aged rat hippocampus.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25941121
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633399
}}
* {{medline-title
|title=Prenatal restraint stress decreases the expression of alpha-7 nicotinic receptor in the brain of adult rat offspring.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25798813
|full-text-url=https://sci-hub.do/10.3109/10253890.2015.1022148
}}
* {{medline-title
|title=Spatial memory deficit across aging: current insights of the role of 5-HT7 receptors.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25642173
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294164
}}
* {{medline-title
|title=Age-Dependent Effect of β-Amyloid Toxicity on Basal Forebrain Cholinergic Neurons and Inflammation in the Rat Brain.
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25187042
|full-text-url=https://sci-hub.do/10.1111/bpa.12199
}}
* {{medline-title
|title=Intracellular activities related to in vitro hippocampal sharp waves are altered in [[CA3]] pyramidal neurons of aged mice.
|date=26.09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25088916
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2014.07.048
}}
* {{medline-title
|title=Comparison of N-methyl-D-aspartate receptor subunit 1 and 4-hydroxynonenal in the hippocampus of natural and chemical-induced aging accelerated mice.
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25022577
|full-text-url=https://sci-hub.do/10.1007/s11064-014-1362-7
}}
* {{medline-title
|title=Hippocampal subregions exhibit both distinct and shared transcriptomic responses to aging and nonneurodegenerative cognitive decline.
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24994846
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271093
}}
* {{medline-title
|title=Interleukin-1β-immunoreactive neurons in the hippocampus and paraventricular nucleus of the hypothalamus after stress stimulation in aged versus adult rats.
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24939320
|full-text-url=https://sci-hub.do/10.1002/jnr.23428
}}
* {{medline-title
|title=Volume of the hippocampal subfields in healthy adults: differential associations with age and a pro-inflammatory genetic variant.
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24947882
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272678
}}
* {{medline-title
|title=Role of oligomeric proanthocyanidins derived from an extract of persimmon fruits in the oxidative stress-related aging process.
|date=22.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24858102
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271875
}}
* {{medline-title
|title=Estradiol replacement extends the window of opportunity for hippocampal function.
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24813636
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090327
}}
* {{medline-title
|title=Deficits of synaptic functions in hippocampal slices prepared from aged mice null α7 nicotinic acetylcholine receptors.
|date=06.06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24769321
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2014.04.018
}}
* {{medline-title
|title=Astrocytic plasticity as a possible mediator of the cognitive improvements after environmental enrichment in aged rats.
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24727294
|full-text-url=https://sci-hub.do/10.1016/j.nlm.2014.04.002
}}
* {{medline-title
|title=Hippocampal subfield volumes at 7T in early Alzheimer's disease and normal aging.
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24684788
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2014.02.021
}}
* {{medline-title
|title=Neuron volumes in hippocampal subfields in delayed poststroke and aging-related dementias.
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24607963
|full-text-url=https://sci-hub.do/10.1097/NEN.0000000000000054
}}
* {{medline-title
|title=Maternal separation impairs long term-potentiation in [[CA1]]-[[CA3]] synapses and hippocampal-dependent memory in old rats.
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24559649
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2014.01.024
}}
* {{medline-title
|title=Moringa oleifera mitigates memory impairment and neurodegeneration in animal model of age-related dementia.
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24454988
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884855
}}
* {{medline-title
|title=Interaction of DHPG-LTD and synaptic-LTD at senescent [[CA3]]-[[CA1]] hippocampal synapses.
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24390964
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959216
}}
* {{medline-title
|title=Behaviorally activated mRNA expression profiles produce signatures of learning and enhanced inhibition in aged rats with preserved memory.
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24349543
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862806
}}
* {{medline-title
|title=Functional proteomics related to energy metabolism of synaptosomes from different neuronal systems of rat hippocampus during aging.
|date=06.12.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24200092
|full-text-url=https://sci-hub.do/10.1021/pr400834g
}}
* {{medline-title
|title=The neuroprotective effect of long-term n-3 polyunsaturated fatty acids supplementation in the cerebral cortex and hippocampus of aging rats.
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24114641
|full-text-url=https://sci-hub.do/10.5114/fn.2013.37708
}}
* {{medline-title
|title=Sex- and region-specific pubertal maturation of the corticotropin-releasing factor receptor system in the rat.
|date=15.04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24115088
|full-text-url=https://sci-hub.do/10.1002/cne.23475
}}
* {{medline-title
|title=Hippocampal interleukin-1beta in the juvenile and middle-aged rat: response to chronic forced swim or high-light open-field stress stimulation.
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24129485

}}
* {{medline-title
|title=AMPA receptor antagonist NBQX attenuates later-life epileptic seizures and autistic-like social deficits following neonatal seizures.
|date=11.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24117347
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262152
}}
* {{medline-title
|title=Linking redox regulation of NMDAR synaptic function to cognitive decline during aging.
|date=02.10.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24089479
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787496
}}
* {{medline-title
|title=Histone deacetylase 2 in the mouse hippocampus: attenuation of age-related increase by caloric restriction.
|date=10.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24093534
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966721
}}
* {{medline-title
|title=Experience-dependent persistent expression of zif268 during rest is preserved in the aged dentate gyrus.
|date=13.09.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24028087
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848627
}}
* {{medline-title
|title=Spatio-temporal differences in perineuronal net expression in the mouse hippocampus, with reference to parvalbumin.
|date=03.12.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24016683
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2013.08.061
}}
* {{medline-title
|title=Surface L-type Ca2  channel expression levels are increased in aged hippocampus.
|date=02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24033980
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947046
}}
* {{medline-title
|title=L-type Ca2  currents at [[CA1]] synapses, but not [[CA3]] or dentate granule neuron synapses, are increased in 3xTgAD mice in an age-dependent manner.
|date=01.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23932880
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864587
}}
* {{medline-title
|title=Integrity of mGluR-LTD in the associative/commissural inputs to [[CA3]] correlates with successful aging in rats.
|date=31.07.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23904603
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728684
}}
* {{medline-title
|title=[Effects of aquaporin-4 gene knockout on behavior changes and cerebral morphology during aging in mice].
|date=05.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23801614

}}
* {{medline-title
|title=Vascular risk moderates associations between hippocampal subfield volumes and memory.
|date=11.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23767922
|full-text-url=https://sci-hub.do/10.1162/jocn_a_00435
}}
* {{medline-title
|title=Bumetanide, an inhibitor of cation-chloride cotransporter isoform 1, inhibits γ-aminobutyric acidergic excitatory actions and enhances sedative actions of midazolam in neonatal rats.
|date=11.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23788048
|full-text-url=https://sci-hub.do/10.1097/ALN.0b013e31829e4b05
}}
* {{medline-title
|title=ApoE4 induces Aβ42, tau, and neuronal pathology in the hippocampus of young targeted replacement apoE4 mice.
|date=17.05.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23684315
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659080
}}
* {{medline-title
|title=[Role of [[GDNF]] in the behavior and cognitive impairment of mice induced by chronic stress and aging].
|date=01.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23662408

}}
* {{medline-title
|title=Neuroprotective role of nanoencapsulated quercetin in combating ischemia-reperfusion induced neuronal damage in young and aged rats.
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23620721
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631169
}}
* {{medline-title
|title=Altered network timing in the [[CA3]]-[[CA1]] circuit of hippocampal slices from aged mice.
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23593474
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620228
}}
* {{medline-title
|title=Immune marker [[CD68]] correlates with cognitive impairment in normally aged rats.
|date=08.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23523271
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2013.02.008
}}
* {{medline-title
|title=Hippocampal excitability is increased in aged mice.
|date=09.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23510762
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2013.03.012
}}
* {{medline-title
|title=Expression of NgR1-antagonizing proteins decreases with aging and cognitive decline in rat hippocampus.
|date=05.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23525710
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651369
}}
* {{medline-title
|title=Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism.
|date=19.03.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23487788
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607034
}}
* {{medline-title
|title=Atrophy of pyramidal neurons and increased stress-induced glutamate levels in [[CA3]] following chronic suppression of adult neurogenesis.
|date=05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23483239
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795860
}}
* {{medline-title
|title=Neurobiological and pharmacological validity of curcumin in ameliorating memory performance of senescence-accelerated mice.
|date=04.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23402943
|full-text-url=https://sci-hub.do/10.1016/j.pbb.2013.02.002
}}
* {{medline-title
|title=Spatial pattern completion deficits in older adults.
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23407761
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571199
}}
* {{medline-title
|title=Partial loss in septo-hippocampal cholinergic neurons alters memory-dependent measures of brain connectivity without overt memory deficits.
|date=06.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23376311
|full-text-url=https://sci-hub.do/10.1016/j.nbd.2013.01.010
}}
* {{medline-title
|title=Plasticity and metaplasticity of adult rat hippocampal mossy fibers induced by neurotrophin-3.
|date=04.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23387385
|full-text-url=https://sci-hub.do/10.1111/ejn.12141
}}
* {{medline-title
|title=Glucocorticoid receptor protein expression in human hippocampus; stability with age.
|date=06.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23290588
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2012.11.019
}}
* {{medline-title
|title=Effects of trauma, hemorrhage and resuscitation in aged rats.
|date=16.02.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23274538
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569488
}}