Редактирование: Aging genes 100 (раздел)

==SIRT1==

* {{medline-title
|title=Anthocyanins attenuate endothelial dysfunction through regulation of uncoupling of nitric oxide synthase in aged rats.
|date=03.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33274583
|full-text-url=https://sci-hub.do/10.1111/acel.13279
}}
* {{medline-title
|title=Sirtuins and Their Implications in Neurodegenerative Diseases from a Drug Discovery Perspective.
|date=05.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33280374
|full-text-url=https://sci-hub.do/10.1021/acschemneuro.0c00696
}}
* {{medline-title
|title=Effects of alpha-mangostin on memory senescence induced by high glucose in human umbilical vein endothelial cells.
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33149857
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585532
}}
* {{medline-title
|title=[[SIRT1]] Activation Using CRISPR/dCas9 Promotes Regeneration of Human Corneal Endothelial Cells through Inhibiting Senescence.
|date=04.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33158256
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694272
}}
* {{medline-title
|title=Histone Deacetylase [[SIRT1]], Smooth Muscle Cell Function, and Vascular Diseases.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33117155
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573826
}}
* {{medline-title
|title=6,4'-dihydroxy-7-methoxyflavanone protects against H O -induced cellular senescence by inducing [[SIRT1]] and inhibiting phosphatidylinositol 3-kinase/Akt pathway activation.
|date=27.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33111210
|full-text-url=https://sci-hub.do/10.1007/s11010-020-03951-z
}}
* {{medline-title
|title=Isoparvifuran isolated from Dalbergia odorifera attenuates H O -induced senescence of BJ cells through [[SIRT1]] activation and AKT/mTOR pathway inhibition.
|date=30.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33010892
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.09.096
}}
* {{medline-title
|title=[[SIRT1]] Is the Target Gene for 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside Alleviating the HUVEC Senescence.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013385
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508177
}}
* {{medline-title
|title=The Role of Sirtuins in Kidney Diseases.
|date=12.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32932720
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555196
}}
* {{medline-title
|title=The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men.
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32919015
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111090
}}
* {{medline-title
|title=Virus-Induced Asthma Exacerbations: [[SIRT1]] Targeted Approach.
|date=13.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32823491
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464235
}}
* {{medline-title
|title=Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts.
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32793997
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09896-6
}}
* {{medline-title
|title=Glucose restriction delays senescence and promotes proliferation of HUVECs via the AMPK/[[SIRT1]]-FOXA3-Beclin1 pathway.
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32768436
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111053
}}
* {{medline-title
|title=Therapeutic Effects of SRT2104 on Lung Injury in Rats with Emphysema via Reduction of Type II Alveolar Epithelial Cell Senescence.
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32722945
|full-text-url=https://sci-hub.do/10.1080/15412555.2020.1797657
}}
* {{medline-title
|title=Latifolin Inhibits Oxidative Stress-Induced Senescence via Upregulation of [[SIRT1]] in Human Dermal Fibroblasts.
|date=01.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32404543
|full-text-url=https://sci-hub.do/10.1248/bpb.b20-00094
}}
* {{medline-title
|title=SRT1720-induced activation of [[SIRT1]] alleviates vascular smooth muscle cell senescence through PKA-dependent phosphorylation of AMPKα at Ser485.
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32421926
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327920
}}
* {{medline-title
|title=miR-128 plays a critical role in murine osteoclastogenesis and estrogen deficiency-induced bone loss.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32292498
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150474
}}
* {{medline-title
|title=Lymphocyte senescence in COPD is associated with decreased sirtuin 1 expression in steroid resistant pro-inflammatory lymphocytes.
|date=01-12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32270742
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153179
}}
* {{medline-title
|title=Therapeutic effects of hydro-alcoholic leaf extract of Withania somnifera on age-induced changes in daily rhythms of Sirt1, Nrf2 and Rev-erbα in the SCN of male Wistar rats.
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32249404
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09875-x
}}
* {{medline-title
|title=The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32214805
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084123
}}
* {{medline-title
|title=Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32158519
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048230
}}
* {{medline-title
|title=Spatiotemporal gating of [[SIRT1]] functions by O-GlcNAcylation is essential for liver metabolic switching and prevents hyperglycemia.
|date=24.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32152092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104039
}}
* {{medline-title
|title=Hydrogen Sulfide Inhibits Homocysteine-Induced Neuronal Senescence by Up-Regulation of [[SIRT1]].
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32132865
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053352
}}
* {{medline-title
|title=[[SIRT1]] and aging related signaling pathways.
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32084459
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111215
}}
* {{medline-title
|title=Tropisetron protects against brain aging via attenuating oxidative stress, apoptosis and inflammation: The role of [[SIRT1]] signaling.
|date=01.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32088214
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.117452
}}
* {{medline-title
|title=Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of [[SIRT1]] activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects.
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32056076
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206476
}}
* {{medline-title
|title=Deacetylation of MRTF-A by [[SIRT1]] defies senescence induced down-regulation of collagen type I in fibroblast cells.
|date=01.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32061777
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2020.165723
}}
* {{medline-title
|title=Chronic Polyphenon-60 or Catechin Treatments Increase Brain Monoamines Syntheses and Hippocampal [[SIRT1]] Levels Improving Cognition in Aged Rats.
|date=26.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31991916
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071257
}}
* {{medline-title
|title=Duck Oil-loaded Nanoemulsion Inhibits Senescence of Angiotensin II-treated Vascular Smooth Muscle Cells by Upregulating [[SIRT1]].
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31970335
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957441
}}
* {{medline-title
|title=Two novel [[SIRT1]] activators, SCIC2 and SCIC2.1, enhance [[SIRT1]]-mediated effects in stress response and senescence.
|date=06-07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31942817
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574383
}}
* {{medline-title
|title=Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1.
|date=23.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31881011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949053
}}
* {{medline-title
|title=The protective role of omentin-1 in IL-1β-induced chondrocyte senescence.
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31852248
|full-text-url=https://sci-hub.do/10.1080/21691401.2019.1699803
}}
* {{medline-title
|title=The Lifespan Extension Ability of Nicotinic Acid Depends on Whether the Intracellular NAD  Level Is Lower than the Sirtuin-Saturating Concentrations.
|date=24.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31878234
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982340
}}
* {{medline-title
|title=Alpha-mangostin decreased cellular senescence in human umbilical vein endothelial cells.
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31792920
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214571
}}
* {{medline-title
|title=Central nervous system [[SIRT1]] expression is required for cued and contextual fear conditioning memory responses in aging mice.
|date=23.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31763496
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839599
}}
* {{medline-title
|title=Does education level protect us from rapid ageing? Sirtuin expression versus age and level of education.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31785216

}}
* {{medline-title
|title=CO ameliorates endothelial senescence induced by 5-fluorouracil through [[SIRT1]] activation.
|date=30.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31704100
|full-text-url=https://sci-hub.do/10.1016/j.abb.2019.108185
}}
* {{medline-title
|title=Long noncoding RNA GAS5 inhibits cell proliferation and fibrosis in diabetic nephropathy by sponging miR-221 and modulating [[SIRT1]] expression.
|date=20.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31631065
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834398
}}
* {{medline-title
|title=The Role of Sirtuin1 in Regulating Endothelial Function, Arterial Remodeling and Vascular Aging.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31572218
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751260
}}
* {{medline-title
|title=Deacetylation of LAMP1 drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer.
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31544977
|full-text-url=https://sci-hub.do/10.1002/jcp.29182
}}
* {{medline-title
|title=Plasma exosomes in OSA patients promote endothelial senescence: effect of long-term adherent continuous positive airway pressure.
|date=13.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31552414
|full-text-url=https://sci-hub.do/10.1093/sleep/zsz217
}}
* {{medline-title
|title=Hydrogen Sulfide Inhibits High Glucose-Induced Neuronal Senescence by Improving Autophagic Flux [i]via[/i] Up-regulation of [[SIRT1]].
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31481873
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710442
}}
* {{medline-title
|title=Activation of the miR-34a-Mediated [[SIRT1]]/mTOR Signaling Pathway by Urolithin A Attenuates D-Galactose-Induced Brain Aging in Mice.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31420820
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985387
}}
* {{medline-title
|title=[Ginsenoside Rg_1 induces leukemia stem cell senescence via [[SIRT1]]/TSC_2 signal axis].
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31359662
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20190218.002
}}
* {{medline-title
|title=miR-23b-3p regulates apoptosis and autophagy via suppressing [[SIRT1]] in lens epithelial cells.
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31338869
|full-text-url=https://sci-hub.do/10.1002/jcb.29270
}}
* {{medline-title
|title=Genetic background, epigenetic factors and dietary interventions which influence human longevity.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31309340
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09824-3
}}
* {{medline-title
|title=Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298565
|full-text-url=https://sci-hub.do/10.1089/cell.2019.0010
}}
* {{medline-title
|title=Interference with the bromodomain epigenome readers drives p21 expression and tumor senescence.
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31265875
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159039
}}
* {{medline-title
|title=Involvement of [i]microRNA-34a[/i] in Age-Related Susceptibility to Oxidative Stress in ARPE-19 Cells by Targeting the Silent Mating Type Information Regulation 2 Homolog 1/p66shc Pathway: Implications for Age-Related Macular Degeneration.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31249522
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584679
}}
* {{medline-title
|title=[[GPR39]] agonist TC-G 1008 ameliorates IL-1β-induced chondrocyte senescence.
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31237151
|full-text-url=https://sci-hub.do/10.1080/21691401.2019.1626405
}}
* {{medline-title
|title=Rational design of novel sirtuin 1 activators via structure-activity insights from application of QSAR modeling.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31217784
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558509
}}
* {{medline-title
|title=Metformin prevents murine ovarian aging.
|date=10.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182682
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594816
}}
* {{medline-title
|title=Time-restricted feeding delays the emergence of the age-associated, neoplastic-prone tissue landscape.
|date=12.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188781
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594823
}}
* {{medline-title
|title=Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/[[SIRT1]] pathway.
|date=10.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182679
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594820
}}
* {{medline-title
|title=[[SIRT1]] protects cochlear hair cell and delays age-related hearing loss via autophagy.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31170533
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.04.003
}}
* {{medline-title
|title=Transcriptome analysis revealed potential mechanisms of differences in physiological stress responses between caged male and female magpies.
|date=03.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31159743
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547487
}}
* {{medline-title
|title=Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31144244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885080
}}
* {{medline-title
|title=Molecular docking analysis of imine stilbene analogs and evaluation of their anti-aging activity using yeast and mammalian cell models.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31132911
|full-text-url=https://sci-hub.do/10.1080/10799893.2019.1605529
}}
* {{medline-title
|title=Molecular and Cellular Characterization of [[SIRT1]] Allosteric Activators.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31087296
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567996
}}
* {{medline-title
|title=Total flavonoids from the Carya cathayensis Sarg. leaves inhibit HUVEC senescence through the miR-34a/[[SIRT1]] pathway.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31106472
|full-text-url=https://sci-hub.do/10.1002/jcb.28986
}}
* {{medline-title
|title=Impaired [[SIRT1]] activity leads to diminution in glomerular endowment without accelerating age-associated GFR decline.
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31087539
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513772
}}
* {{medline-title
|title=Estrogen-[[SIRT1]] Axis Plays a Pivotal Role in Protecting Arteries Against Menopause-Induced Senescence and Atherosclerosis.
|date=01.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31105126
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976724
}}
* {{medline-title
|title=Spatio-temporal expression profile of sirtuins during aging of the annual fish Nothobranchius furzeri.
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31075496
|full-text-url=https://sci-hub.do/10.1016/j.gep.2019.05.001
}}
* {{medline-title
|title=Protective effect of vildagliptin on [[TNF]]-α-induced chondrocyte senescence.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026379
|full-text-url=https://sci-hub.do/10.1002/iub.2049
}}
* {{medline-title
|title=Polymorphism rs7895833 in the [[SIRT1]] gene and its association with dyslipidaemia in the elderly.
|date=07-08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31040057
|full-text-url=https://sci-hub.do/10.1016/j.regg.2019.01.008
}}
* {{medline-title
|title=Modulation of miR-34a/[[SIRT1]] signaling protects cochlear hair cells against oxidative stress and delays age-related hearing loss through coordinated regulation of mitophagy and mitochondrial biogenesis.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026620
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.03.013
}}
* {{medline-title
|title=Nicotinamide mononucleotide promotes osteogenesis and reduces adipogenesis by regulating mesenchymal stromal cells via the [[SIRT1]] pathway in aged bone marrow.
|date=18.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31000692
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472410
}}
* {{medline-title
|title=Cordycepin, an Active Constituent of Nutrient Powerhouse and Potential Medicinal Mushroom [i]Cordyceps militaris[/i] Linn., Ameliorates Age-Related Testicular Dysfunction in Rats.
|date=23.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31018574
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520895
}}
* {{medline-title
|title=The resistant effect of [[SIRT1]] in oxidative stress-induced senescence of rat nucleus pulposus cell is regulated by Akt-FoxO1 pathway.
|date=31.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30967498
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509061
}}
* {{medline-title
|title=Photobiomodulation and Coenzyme Q  Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30983970
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434313
}}
* {{medline-title
|title=The role of [[SIRT1]] in neuroinflammation and cognitive dysfunction in aged rats after anesthesia and surgery.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30972182
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456566
}}
* {{medline-title
|title=NAD  supplementation rejuvenates aged gut adult stem cells.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30917412
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516145
}}
* {{medline-title
|title=[[NMNAT2]]-mediated NAD  generation is essential for quality control of aged oocytes.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30909324
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516161
}}
* {{medline-title
|title=Mitochondrial dysfunction in neurodegenerative diseases and the potential countermeasure.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30889315
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566063
}}
* {{medline-title
|title=Drugs targeting [[SIRT1]], a new generation of therapeutics for osteoporosis and other bone related disorders?
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862606
|full-text-url=https://sci-hub.do/10.1016/j.phrs.2019.03.007
}}
* {{medline-title
|title=Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks.
|date=11.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862067
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429360
}}
* {{medline-title
|title=Knockout of receptor for advanced glycation end-products attenuates age-related renal lesions.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30794349
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413655
}}
* {{medline-title
|title=Stress-induced precocious aging in PD-patient iPSC-derived NSCs may underlie the pathophysiology of Parkinson's disease.
|date=04.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30718471
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362163
}}
* {{medline-title
|title=Bone Marrow Mesenchymal Stem Cells-Derived Exosomal MiR-29b-3p Regulates Aging-Associated Insulin Resistance.
|date=26.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30715852
|full-text-url=https://sci-hub.do/10.1021/acsnano.8b09375
}}
* {{medline-title
|title=Strength training and aerobic exercise alter mitochondrial parameters in brown adipose tissue and equally reduce body adiposity in aged rats.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30712161
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00663-x
}}
* {{medline-title
|title=Novel biomolecules of ageing, sex differences and potential underlying mechanisms of telomere shortening in coronary artery disease.
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30684534
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.020
}}
* {{medline-title
|title=Generation of a novel model of primary human cell senescence through Tenovin-6 mediated inhibition of sirtuins.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30666570
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535423
}}
* {{medline-title
|title=Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30659954
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.016
}}
* {{medline-title
|title=Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism.
|date=23.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30673631
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366955
}}
* {{medline-title
|title=Protective Role of Endogenous Kallistatin in Vascular Injury and Senescence by Inhibiting Oxidative Stress and Inflammation.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30622668
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304815
}}
* {{medline-title
|title=NKT-like cells reveal higher than T lymphocytes expression of cellular protective proteins HSP70 and [[SOD2]] and comparably increased expression of [[SIRT1]] in the oldest seniors.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30633320
|full-text-url=https://sci-hub.do/10.5603/FHC.a2018.0025
}}
* {{medline-title
|title=Melatonin regulates the activities of ovary and delays the fertility decline in female animals via MT1/AMPK pathway.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30597622
|full-text-url=https://sci-hub.do/10.1111/jpi.12550
}}
* {{medline-title
|title=Exercise training augments Sirt1-signaling and attenuates cardiac inflammation in D-galactose induced-aging rats.
|date=23.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30582744
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326662
}}
* {{medline-title
|title=Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30537739
|full-text-url=https://sci-hub.do/10.1159/000495895
}}
* {{medline-title
|title=Diesel exhaust exposure intensifies inflammatory and structural changes associated with lung aging in mice.
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30530184
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.11.139
}}
* {{medline-title
|title=CD56bright cells respond to stimulation until very advanced age revealing increased expression of cellular protective proteins [[SIRT1]], HSP70 and [[SOD2]].
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30534181
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262966
}}
* {{medline-title
|title=Amentoflavone Induces Autophagy and Modulates p53.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30507085
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275431
}}
* {{medline-title
|title=Induction of a senescent like phenotype and loss of gap junctional intercellular communication by carbon nanoparticle exposure of lung epithelial cells.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30476532
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.017
}}
* {{medline-title
|title=Sirtuins: Developing Innovative Treatments for Aged-Related Memory Loss and Alzheimer's Disease.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30484407
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538488
}}
* {{medline-title
|title=N-acetylcysteine ameliorates cisplatin-induced renal senescence and renal interstitial fibrosis through sirtuin1 activation and p53 deacetylation.
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30447351
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.11.006
}}
* {{medline-title
|title=Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice.
|date=20.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296764
}}
* {{medline-title
|title=Metformin Is a Direct [[SIRT1]]-Activating Compound: Computational Modeling and Experimental Validation.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30459716
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232372
}}
* {{medline-title
|title=Hsp90 Stabilizes [[SIRT1]] Orthologs in Mammalian Cells and [i]C. elegans[/i].
|date=20.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463299
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274930
}}
* {{medline-title
|title=Sirtuins and NAD  in the Development and Treatment of Metabolic and Cardiovascular Diseases.
|date=14.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30355082
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206880
}}
* {{medline-title
|title=[[SIRT1]] deacetylase in aging-induced neuromuscular degeneration and amyotrophic lateral sclerosis.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30295421
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260920
}}
* {{medline-title
|title=Prevention of Senescence in Vasculature Through Quiescence.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30259779
|full-text-url=https://sci-hub.do/10.1089/rej.2018.2138
}}
* {{medline-title
|title=Melatonin and inflammation-Story of a double-edged blade.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30242884
|full-text-url=https://sci-hub.do/10.1111/jpi.12525
}}
* {{medline-title
|title=[[ALDH2]] mediates the dose-response protection of chronic ethanol against endothelial senescence through [[SIRT1]]/p53 pathway.
|date=12.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217444
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.08.081
}}
* {{medline-title
|title=Resveratrol-loaded nanoemulsion prevents cognitive decline after abdominal surgery in aged rats.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30196020
|full-text-url=https://sci-hub.do/10.1016/j.jphs.2018.08.006
}}
* {{medline-title
|title=Endothelial [[SIRT1]] prevents age-induced impairment of vasodilator responses by enhancing the expression and activity of soluble guanylyl cyclase in smooth muscle cells.
|date=01.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30165439
|full-text-url=https://sci-hub.do/10.1093/cvr/cvy212
}}
* {{medline-title
|title=Effects of Ginsenoside Rg3 on fatigue resistance and [[SIRT1]] in aged rats.
|date=01.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30144466
|full-text-url=https://sci-hub.do/10.1016/j.tox.2018.08.010
}}
* {{medline-title
|title=[[PARP1]] inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD  levels and increasing [[SIRT1]] activity.
|date=23.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30139380
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107962
}}
* {{medline-title
|title=Moderate calorie restriction attenuates age‑associated alterations and improves cardiac function by increasing [[SIRT1]] and [[SIRT3]] expression.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30132522
|full-text-url=https://sci-hub.do/10.3892/mmr.2018.9390
}}
* {{medline-title
|title=Liver regeneration in aged mice: new insights.
|date=28.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30157472
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128415
}}
* {{medline-title
|title=Phenolic Plant Extracts Induce Sirt1 Activity and Increase Antioxidant Levels in the Rabbit's Heart and Liver.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30116475
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079382
}}
* {{medline-title
|title=Defect of [[SIRT1]]-FoxO3a axis is associated with the production of reactive oxygen species during protein kinase CK2 downregulation-mediated cellular senescence and nematode aging.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30103847
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507845
}}
* {{medline-title
|title=Master athletes have higher miR-7, [[SIRT3]] and [[SOD2]] expression in skeletal muscle than age-matched sedentary controls.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30107294
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092475
}}
* {{medline-title
|title=Tenovin-1 Induces Senescence and Decreases Wound-Healing Activity in Cultured Rat Primary Astrocytes.
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30092626
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513186
}}
* {{medline-title
|title=[[PGC]]-1α Protects [[RPE]] Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis.
|date=07.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30087287
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121367
}}
* {{medline-title
|title=Effect of oral appliance on circulating leukocyte telomere length and [[SIRT1]] in obstructive sleep apnea.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30030618
|full-text-url=https://sci-hub.do/10.1007/s00784-018-2560-5
}}
* {{medline-title
|title=miR-34a Promotes Vascular Smooth Muscle Cell Calcification by Downregulating [[SIRT1]] (Sirtuin 1) and Axl (AXL Receptor Tyrosine Kinase).
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30026277
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.311298
}}
* {{medline-title
|title=A [[SIRT1]]-centered circuitry regulates breast cancer stemness and metastasis.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30038266
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283862
}}
* {{medline-title
|title=Apelin/APJ axis improves angiotensin II-induced endothelial cell senescence through AMPK/[[SIRT1]] signaling pathway.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30002688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040122
}}
* {{medline-title
|title=Sirtuin 1 and Alzheimer's disease: An up-to-date review.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30007474
|full-text-url=https://sci-hub.do/10.1016/j.npep.2018.07.001
}}
* {{medline-title
|title=CCAR-1 is a negative regulator of the heat-shock response in Caenorhabditis elegans.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003683
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156500
}}
* {{medline-title
|title=Kallistatin attenuates endothelial senescence by modulating Let-7g-mediated miR-34a-[[SIRT1]]-eNOS pathway.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29992759
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111868
}}
* {{medline-title
|title=Serum containing Buyang Huanwu decoction prevents age-associated migration and invasion of human vascular smooth muscle cells by up regulating [[SIRT1]] expression.
|date=17.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29952352
|full-text-url=https://sci-hub.do/10.5582/bst.2018.01063
}}
* {{medline-title
|title=Role of accelerated aging in limb muscle wasting of patients with COPD.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29970961
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022820
}}
* {{medline-title
|title=Resveratrol promotes oxidative stress to drive [[DLC1]] mediated cellular senescence in cancer cells.
|date=15.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29964052
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.06.031
}}
* {{medline-title
|title=Mesenchymal stem cells confer resistance to doxorubicin-induced cardiac senescence by inhibiting microRNA-34a.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29928373
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004710
}}
* {{medline-title
|title=The circadian clock in adult neural stem cell maintenance.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29886147
|full-text-url=https://sci-hub.do/10.1016/j.pneurobio.2018.05.007
}}
* {{medline-title
|title=Resveratrol reduces senescence-associated secretory phenotype by [[SIRT1]]/NF-κB pathway in gut of the annual fish Nothobranchius guentheri.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29908321
|full-text-url=https://sci-hub.do/10.1016/j.fsi.2018.06.027
}}
* {{medline-title
|title=Loss of [[NAMPT]] in aging retinal pigment epithelium reduces NAD  availability and promotes cellular senescence.
|date=12.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905535
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046249
}}
* {{medline-title
|title=Mushroom extract inhibits ultraviolet B-induced cellular senescence in human keratinocytes.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29860669
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021292
}}
* {{medline-title
|title=[[SIRT1]], miR-132 and miR-212 link human longevity to Alzheimer's Disease.
|date=31.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29855513
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981646
}}
* {{medline-title
|title=Endothelial progenitor cells from aged subjects display decreased expression of sirtuin 1, angiogenic functions, and increased senescence.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29851177
|full-text-url=https://sci-hub.do/10.1002/cbin.10999
}}
* {{medline-title
|title=Rejuvenating Aged Hematopoietic Stem Cells Through Improvement of Mitochondrial Function.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29797808
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973912
}}
* {{medline-title
|title=Berberine Improves Cognitive Deficiency and Muscular Dysfunction via Activation of the AMPK/[[SIRT1]]/[[PGC]]-1a Pathway in Skeletal Muscle from Naturally Aging Rats.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29806860
|full-text-url=https://sci-hub.do/10.1007/s12603-018-1015-7
}}
* {{medline-title
|title=[[SIRT1]] reverses senescence via enhancing autophagy and attenuates oxidative stress-induced apoptosis through promoting p53 degradation.
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29803744
|full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2018.05.174
}}
* {{medline-title
|title=Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774638
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052398
}}
* {{medline-title
|title=Dietary polyphenols and neurogenesis: Molecular interactions and implication for brain ageing and cognition.
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29753753
|full-text-url=https://sci-hub.do/10.1016/j.neubiorev.2018.05.011
}}
* {{medline-title
|title=Whey Protein Attenuates Angiotensin II-Primed Premature Senescence of Vascular Smooth Muscle Cells through Upregulation of [[SIRT1]].
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29725214
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932937
}}
* {{medline-title
|title=Role of hypothalamus in aging and its underlying cellular mechanisms.
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29729230
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.04.008
}}
* {{medline-title
|title=The variable role of [[SIRT1]] in the maintenance and differentiation of mesenchymal stem cells.
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29715067
|full-text-url=https://sci-hub.do/10.2217/rme-2017-0128
}}
* {{medline-title
|title=Sirtuins in Renal Health and Disease.
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29712732
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050939
}}
* {{medline-title
|title=Physical Exercise Improves Aging-Related Changes in Angiotensin, IGF-1, [[SIRT1]], [[SIRT3]], and VEGF in the Substantia Nigra.
|date=10.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659739
|full-text-url=https://sci-hub.do/10.1093/gerona/gly072
}}
* {{medline-title
|title=MeCP2-mediated epigenetic regulation in senescent endothelial progenitor cells.
|date=03.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615114
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883541
}}
* {{medline-title
|title=Natural products with anti-aging potential: Affected targets and molecular mechanisms.
|date=01.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29597027
|full-text-url=https://sci-hub.do/10.1016/j.biotechadv.2018.03.012
}}
* {{medline-title
|title=[Effect of microRNA-34a/[[SIRT1]]/p53 signal pathway on notoginsenoside R₁ delaying vascular endothelial cell senescence].
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29600625
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180110.001
}}
* {{medline-title
|title=[[SIRT1]] and microRNAs: The role in breast, lung and prostate cancers.
|date=01.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29574020
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.03.023
}}
* {{medline-title
|title=Leukotriene D4 induces cellular senescence in osteoblasts.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29587204
|full-text-url=https://sci-hub.do/10.1016/j.intimp.2017.12.027
}}
* {{medline-title
|title=Impairment of an Endothelial NAD -H S Signaling Network Is a Reversible Cause of Vascular Aging.
|date=22.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570999
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884172
}}
* {{medline-title
|title=Differential gene expression of sirtuins between somatotropinomas and nonfunctioning pituitary adenomas.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29564694
|full-text-url=https://sci-hub.do/10.1007/s11102-018-0881-7
}}
* {{medline-title
|title=Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice.
|date=06.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29514072
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854409
}}
* {{medline-title
|title=Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29476819
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.004
}}
* {{medline-title
|title=[[HGF]] and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the [[SIRT1]]/[[FOXO1]] Signaling Pathway.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29462806
|full-text-url=https://sci-hub.do/10.1159/000487559
}}
* {{medline-title
|title=The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29407880
|full-text-url=https://sci-hub.do/10.1016/j.atherosclerosis.2018.01.043
}}
* {{medline-title
|title=Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction.
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29366775
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.01.018
}}
* {{medline-title
|title=Antagonism of cysteinyl leukotriene receptor 1 (cysLTR1) by montelukast suppresses cell senescence of chondrocytes.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29331588
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2017.12.021
}}
* {{medline-title
|title=Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress.
|date=20.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325896
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.01.007
}}
* {{medline-title
|title=Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury.
|date=11.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29326403
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811244
}}
* {{medline-title
|title=Acetylshikonin from Zicao attenuates cognitive impairment and hippocampus senescence in d-galactose-induced aging mouse model via upregulating the expression of [[SIRT1]].
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325995
|full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2018.01.007
}}
* {{medline-title
|title=Dexamethasone downregulates [[SIRT1]] and [[IL6]] and upregulates [[EDN1]] genes in stem cells derived from gingivae via the AGE/RAGE pathway.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29302812
|full-text-url=https://sci-hub.do/10.1007/s10529-017-2493-0
}}
* {{medline-title
|title=Sirtuins in Brain Aging and Neurological Disorders.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29283326
|full-text-url=https://sci-hub.do/10.1615/CritRevEukaryotGeneExpr.2017019532
}}
* {{medline-title
|title=[Aging-related change of erectile function and the expression of [[SIRT1]]].
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29282911

}}
* {{medline-title
|title=Expression of Sirtuins in the Retinal Neurons of Mice, Rats, and Humans.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29249955
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715387
}}
* {{medline-title
|title=Maternal aging affects oocyte resilience to carbonyl cyanide-m-chlorophenylhydrazone -induced mitochondrial dysfunction in cows.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29182624
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705080
}}
* {{medline-title
|title=Nicotinamide phosphoribosyltransferase delays cellular senescence by upregulating [[SIRT1]] activity and antioxidant gene expression in mouse cells.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29178516
|full-text-url=https://sci-hub.do/10.1111/gtc.12542
}}
* {{medline-title
|title=Stem Cells and Progenitors in Human Peripheral Blood Get Activated by Extremely Active Resveratrol (XAR™).
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177909
|full-text-url=https://sci-hub.do/10.1007/s12015-017-9784-7
}}
* {{medline-title
|title=Fibroblast growth factor 21 delayed endothelial replicative senescence and protected cells from H O -induced premature senescence through [[SIRT1]].
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29118911
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666058
}}
* {{medline-title
|title=Tucum-do-Cerrado (Bactris setosa Mart.) May Promote Anti-Aging Effect by Upregulating [[SIRT1]]-Nrf2 Pathway and Attenuating Oxidative Stress and Inflammation.
|date=14.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135935
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707715
}}
* {{medline-title
|title=Maternal high calorie diet induces mitochondrial dysfunction and senescence phenotype in subcutaneous fat of newborn mice.
|date=13.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29137352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663524
}}
* {{medline-title
|title=O-GlcNAcylation of [[SIRT1]] enhances its deacetylase activity and promotes cytoprotection under stress.
|date=14.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29133780
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684413
}}
* {{medline-title
|title=Aging as an Epigenetic Phenomenon.
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081695
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635645
}}
* {{medline-title
|title=MeCP2 mediated dysfunction in senescent EPCs.
|date=03.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29108229
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667962
}}
* {{medline-title
|title=Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063982
|full-text-url=https://sci-hub.do/10.1007/s10571-017-0557-2
}}
* {{medline-title
|title=A comparative study of anti-aging properties and mechanism: resveratrol and caloric restriction.
|date=12.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29029466
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630366
}}
* {{medline-title
|title=Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence.
|date=17.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29041897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645932
}}
* {{medline-title
|title=Negative regulation of Sirtuin 1 by AMP-activated protein kinase promotes metformin-induced senescence in hepatocellular carcinoma xenografts.
|date=28.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28964787
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2017.09.027
}}
* {{medline-title
|title=Blocking [[SIRT1]] inhibits cell proliferation and promotes aging through the PI3K/AKT pathway.
|date=01.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28962864
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2017.09.037
}}
* {{medline-title
|title=[[SIRT1]] is a positive regulator of in vivo bone mass and a therapeutic target for osteoporosis.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28937996
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609767
}}
* {{medline-title
|title=[Protective effect of total saponins of Panax notoginseng combined with total flavonoids of epimedium on D-galactose-incuced senescence of H9c2 cell].
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28952264
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.2017.0012
}}
* {{medline-title
|title=[[SIRT1]] is a transcriptional enhancer of the glucocorticoid receptor acting independently to its deacetylase activity.
|date=05.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28923345
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756502
}}
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
* {{medline-title
|title=The effect of exercise, resveratrol or their combination on Sarcopenia in aged rats via regulation of AMPK/Sirt1 pathway.
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847722
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.032
}}
* {{medline-title
|title=Chronic Silymarin, Quercetin and Naringenin Treatments Increase Monoamines Synthesis and Hippocampal Sirt1 Levels Improving Cognition in Aged Rats.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28808887
|full-text-url=https://sci-hub.do/10.1007/s11481-017-9759-0
}}
* {{medline-title
|title=Aquatide Activation of [[SIRT1]] Reduces Cellular Senescence through a [[SIRT1]]-[[FOXO1]]-Autophagy Axis.
|date=01.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28822991
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590795
}}
* {{medline-title
|title=Obesity and aging diminish sirtuin 1 ([[SIRT1]])-mediated deacetylation of [[SIRT3]], leading to hyperacetylation and decreased activity and stability of [[SIRT3]].
|date=20.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28808064
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655509
}}
* {{medline-title
|title=Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging.
|date=10.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28802039
|full-text-url=https://sci-hub.do/10.1016/j.cell.2017.07.042
}}
* {{medline-title
|title=High glucose and free fatty acids induce endothelial progenitor cell senescence via [[PGC]]-1α/[[SIRT1]] signaling pathway.
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28786152
|full-text-url=https://sci-hub.do/10.1002/cbin.10833
}}
* {{medline-title
|title=Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28767699
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540417
}}
* {{medline-title
|title=Comparing the Effects of Melatonin with Caloric Restriction in the Hippocampus of Aging Mice: Involvement of Sirtuin1 and the FOXOs Pathway.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28770437
|full-text-url=https://sci-hub.do/10.1007/s11064-017-2369-7
}}
* {{medline-title
|title=Role of Kallistatin Treatment in Aging and Cancer by Modulating miR-34a and miR-21 Expression.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28744338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506461
}}
* {{medline-title
|title=Inflammation, Stem Cells, and the Aging Hypothalamus.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28756738
|full-text-url=https://sci-hub.do/10.1089/rej.2017.2002
}}
* {{medline-title
|title=Myricetin improves endurance capacity and mitochondrial density by activating [[SIRT1]] and [[PGC]]-1α.
|date=24.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28740165
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524912
}}
* {{medline-title
|title=Moving to the Rhythm with Clock (Circadian) Genes, Autophagy, mTOR, and [[SIRT1]] in Degenerative Disease and Cancer.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28721811
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600856
}}
* {{medline-title
|title=The emerging role of alternative splicing in senescence and aging.
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28703423
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595669
}}
* {{medline-title
|title=miR-34a and miR-9 are overexpressed and SIRT genes are downregulated in peripheral blood mononuclear cells of aging humans.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28699360
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544174
}}
* {{medline-title
|title=Regulation of [[SIRT1]]/AMPK axis is critically involved in gallotannin-induced senescence and impaired autophagy leading to cell death in hepatocellular carcinoma cells.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676953
|full-text-url=https://sci-hub.do/10.1007/s00204-017-2021-y
}}
* {{medline-title
|title=[[SIRT1]] and [[SIRT6]] Signaling Pathways in Cardiovascular Disease Protection.
|date=10.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28661724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824538
}}
* {{medline-title
|title=Effects of Resveratrol and other Polyphenols on Sirt1: Relevance to Brain Function During Aging.
|date=30.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883375
}}
* {{medline-title
|title=Reduction in podocyte [[SIRT1]] accelerates kidney injury in aging mice.
|date=01.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28615249
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625108
}}
* {{medline-title
|title=Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs.
|date=12.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28611316
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509453
}}
* {{medline-title
|title=Ursolic Acid Mediates Hepatic Protection through Enhancing of anti-aging Biomarkers.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28558631
|full-text-url=https://sci-hub.do/10.2174/1874609810666170531103140
}}
* {{medline-title
|title=The NAD /[[PARP1]]/[[SIRT1]] Axis in Aging.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28537485
|full-text-url=https://sci-hub.do/10.1089/rej.2017.1980
}}
* {{medline-title
|title=Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota.
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28552621
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581719
}}
* {{medline-title
|title=Kallistatin reduces vascular senescence and aging by regulating microRNA-34a-[[SIRT1]] pathway.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28544111
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506400
}}
* {{medline-title
|title=Bushen-Yizhi formula ameliorates cognitive dysfunction through [[SIRT1]]/ER stress pathway in SAMP8 mice.
|date=25.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28521305
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564772
}}
* {{medline-title
|title=Caveolin-1 deficiency induces premature senescence with mitochondrial dysfunction.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28514055
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506423
}}
* {{medline-title
|title=Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-[[FOXO1]] pathway.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28507478
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427465
}}
* {{medline-title
|title=Steroidogenesis decline accompanied with reduced antioxidation and endoplasmic reticulum stress in mice testes during ageing.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28488286
|full-text-url=https://sci-hub.do/10.1111/and.12816
}}
* {{medline-title
|title=Exogenous nicotinamide supplementation and moderate physical exercise can attenuate the aging process in skeletal muscle of rats.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28477081
|full-text-url=https://sci-hub.do/10.1007/s10522-017-9705-9
}}
* {{medline-title
|title=Caloric restriction delays early phases of carcinogenesis via effects on the tissue microenvironment.
|date=30.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28415598
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482635
}}
* {{medline-title
|title=During yeast chronological aging resveratrol supplementation results in a short-lived phenotype Sir2-dependent.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28412652
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397018
}}
* {{medline-title
|title=Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts.
|date=01.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28385812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495944
}}
* {{medline-title
|title=Regulation of stem cell aging by [[SIRT1]] - Linking metabolic signaling to epigenetic modifications.
|date=05.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28392411
|full-text-url=https://sci-hub.do/10.1016/j.mce.2017.03.031
}}
* {{medline-title
|title=Ampelopsin attenuates the atrophy of skeletal muscle from d-gal-induced aging rats through activating AMPK/[[SIRT1]]/PGC-1α signaling cascade.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28364603
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2017.03.070
}}
* {{medline-title
|title=[[SIRT1]] Polymorphisms and Serum-Induced [[SIRT1]] Protein Expression in Aging and Frailty: The CHAMP Study.
|date=01.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28329314
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279142
}}
* {{medline-title
|title=Melatonin reverses H  O  -induced senescence in SH-SY5Y cells by enhancing autophagy via sirtuin 1 deacetylation of the RelA/p65 subunit of NF-κB.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28295567
|full-text-url=https://sci-hub.do/10.1111/jpi.12407
}}
* {{medline-title
|title=Alkylresorcinols activate [[SIRT1]] and delay ageing in Drosophila melanogaster.
|date=02.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28252007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333101
}}
* {{medline-title
|title=Tat-Mediated Induction of miRs-34a