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==HR== {{medline-entry |title=Patients with hip fracture and total hip arthroplasty surgery differ in anthropometric, but not cardiovascular screening abnormalities. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33267795 |keywords=* Aging * Cardiovascular reactivity * Heart rate variability * Hip fracture * Total hip arthroplasty |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713041 }} {{medline-entry |title=Clinical Role of Lung Ultrasound for the Diagnosis and Prognosis of Coronavirus Disease Pneumonia in Elderly Patients: A Pivotal Study. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33271558 |keywords=* Aging * Coronavirus disease * Elderly * Lung ultrasound * Severe acute respiratory syndrome-coronavirus-2 |full-text-url=https://sci-hub.do/10.1159/000512209 }} {{medline-entry |title=The Relationship of Accelerometer-Assessed Standing Time With and Without Ambulation and Mortality: The WHI OPACH Study. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33225345 |keywords=* Accelerometer * Longevity * Physical activity |full-text-url=https://sci-hub.do/10.1093/gerona/glaa227 }} {{medline-entry |title=Age-related myofiber atrophy in old mice is reversed by ten weeks voluntary high-resistance wheel running. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33181317 |keywords=* Aging * Exercise * Mouse model * Muscle morphology * Skeletal muscle * Training |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111150 }} {{medline-entry |title=Predicted Skeletal Muscle Mass and 4-Year Cardiovascular Disease Incidence in Middle-Aged and Elderly Participants of IKARIA Prospective Epidemiological Study: The Mediating Effect of Sex and Cardiometabolic Factors. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33121164 |keywords=* aging * body composition * gender * heart disease * lean mass * obesity * primary prevention * women |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693172 }} {{medline-entry |title=Obesity is associated with early hip fracture risk in postmenopausal women: a 25-year follow-up. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33095419 |keywords=* Aging * Body mass index * Bone mineral density * Follow-up study * General population * Hip fracture * Menopause * Obesity |full-text-url=https://sci-hub.do/10.1007/s00198-020-05665-w }} {{medline-entry |title=ATM inhibition synergizes with fenofibrate in high grade serous ovarian cancer cells. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33024871 |keywords=* Biochemistry * Bioinformatics * Cancer research * Cell biology * Cellular metabolism * Cellular senescence * Drug combinations * Homologous recombination * Metabolite * Molecular biology * PPARa |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527645 }} {{medline-entry |title=Effectiveness of adjuvant FOLFOX vs 5FU/LV in adults over age 65 with stage II and III colon cancer using a novel hybrid approach. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33015888 |keywords=* aging * cancer * chemotherapy * comparative effectiveness research * pharmacoepidemiology |full-text-url=https://sci-hub.do/10.1002/pds.5148 }} {{medline-entry |title=Age, Frailty, and Comorbidity as Prognostic Factors for Short-Term Outcomes in Patients With Coronavirus Disease 2019 in Geriatric Care. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32978065 |mesh-terms=* Age Factors * Aged * Aged, 80 and over * Betacoronavirus * COVID-19 * Comorbidity * Coronavirus Infections * Female * Frail Elderly * Geriatrics * Humans * Male * Models, Statistical * Outcome Assessment, Health Care * Pandemics * Pneumonia, Viral * Prognosis * SARS-CoV-2 * Survival Analysis * Sweden |keywords=* COVID-19 * aging * comorbidity * frailty * geriatrics * survival |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427570 }} {{medline-entry |title=Clinical and demographic parameters predict the progression from mild cognitive impairment to dementia in elderly patients. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32918697 |keywords=* Aging * Cox regression * Dementia * Follow-up * Mild cognitive impairment |full-text-url=https://sci-hub.do/10.1007/s40520-020-01697-8 }} {{medline-entry |title=Plasma Dehydroepiandrosterone Sulfate and Cardiovascular Disease Risk in Older Men and Women. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32785663 |keywords=* DHEA-S * aging * heart failure * mortality |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526732 }} {{medline-entry |title=High intensity interval training combined with L-citrulline supplementation: Effects on physical performance in healthy older adults. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32721549 |keywords=* Aging * Body composition * Exercise * Mobility * Nutrition |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111036 }} {{medline-entry |title=Associations of blood pressure with risk of injurious falls in old age vary by functional status: A cohort study. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32738383 |keywords=* Aging * Blood pressure * Falls * Injury * Swedish National study on Aging and Care in Kungsholmen (SNAC-K) |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111038 }} {{medline-entry |title=Epigenetic age acceleration and clinical outcomes in gliomas. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32692766 |mesh-terms=* Adult * Aging * DNA Methylation * Epigenesis, Genetic * Female * Glioma * Humans * Male * Middle Aged * Prognosis * Survival Analysis |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373289 }} {{medline-entry |title=Do Stairs Inhibit Seniors Who Live on Upper Floors From Going Out? |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32666833 |keywords=* active aging * activity monitor * homebound * mobility * walk-up buildings |full-text-url=https://sci-hub.do/10.1177/1937586720936588 }} {{medline-entry |title=Age-specific acute changes in carotid-femoral pulse wave velocity with head-up tilt. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32634245 |keywords=* arterial function * arterial stiffness * blood pressure * early vascular aging * pressure dependence |full-text-url=https://sci-hub.do/10.1093/ajh/hpaa101 }} {{medline-entry |title=Pre-frailty status increases the risk of rehospitalization in patients after elective cardiac surgery without complication. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32531126 |mesh-terms=* Aged * Cardiac Surgical Procedures * Elective Surgical Procedures * Female * Frailty * Humans * Male * Patient Readmission * Postoperative Complications * Retrospective Studies * Risk |keywords=* adverse events * aging * cardiac surgery * frailty * rehospitalization |full-text-url=https://sci-hub.do/10.1111/jocs.14550 }} {{medline-entry |title=Comparative Performance of Creatinine-Based GFR Estimation Equations in Exceptional Longevity: The Rugao Longevity and Ageing Study. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32546991 |mesh-terms=* Aged, 80 and over * Creatinine * Female * Glomerular Filtration Rate * Humans * Kidney Function Tests * Longevity * Male * Mortality * Predictive Value of Tests * Renal Insufficiency * Reproducibility of Results * Risk Factors |keywords=* equation * exceptional longevity * glomerular filtration rate * kidney function * mortality |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266309 }} {{medline-entry |title=Sex-and race-specific associations of protein intake with change in muscle mass and physical function in older adults: the Health, Aging, and Body Composition (Health ABC) Study. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32520344 |mesh-terms=* Aged * Aged, 80 and over * Aging * Biomass * Body Composition * Body Weight * Dietary Proteins * Female * Humans * Independent Living * Male * Muscle Development * Muscle Strength * Muscles * Prospective Studies * Sex Factors |keywords=* appendicular lean body mass * community-dwelling * gait speed * mobility limitation * old age * optimal intake * physical performance * spline functions |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326591 }} {{medline-entry |title=Deterioration of bone microstructure by aging and menopause in Japanese healthy women: analysis by [[HR]]-pQCT. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32519249 |mesh-terms=* Absorptiometry, Photon * Adult * Aged * Aging * Asian Continental Ancestry Group * Bone Density * Bone and Bones * Cancellous Bone * Cortical Bone * Female * Finite Element Analysis * Humans * Japan * Linear Models * Menopause * Middle Aged * Porosity * Tomography, X-Ray Computed |keywords=* Bone microstructure * Estimated bone strength * High resolution peripheral quantitative CT (HR-pQCT) * Japanese women * Non-metric trabecular parameter |full-text-url=https://sci-hub.do/10.1007/s00774-020-01115-z }} {{medline-entry |title=Association between Low Protein Intake and Mortality in Patients with Type 2 Diabetes. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32492838 |keywords=* aging * diabetes * mortality * nutritional support * protein intake |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352318 }} {{medline-entry |title=CAUSES, mortality rates and risk factors of death in community-dwelling Europeans aged 50 years and over: Results from the Survey of Health, Ageing and Retirement in Europe 2013-2015. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32325305 |mesh-terms=* Activities of Daily Living * Aged * Aging * Cohort Studies * Europe * Humans * Independent Living * Male * Middle Aged * Mortality * Proportional Hazards Models * Prospective Studies * Retirement * Risk Factors * Surveys and Questionnaires |keywords=* Aging * Comorbidity * Depressive symptoms * Diseases * Mortality risk |full-text-url=https://sci-hub.do/10.1016/j.archger.2020.104035 }} {{medline-entry |title=Estimation of Wave Condition Number From Pressure Waveform Alone and Its Changes With Advancing Age in Healthy Women and Men. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32328003 |keywords=* arterial wave reflection * cardiovascular biomarker * optimum cardiovascular function * vascular aging * wave condition number |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161432 }} {{medline-entry |title=Extended in vitro culture of primary human mesenchymal stem cells downregulates Brca1-related genes and impairs DNA double-strand break recognition. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32333827 |keywords=* BRCA1 * DNA repair * cellular aging * homologous recombination * mesenchymal stem cells |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327915 }} {{medline-entry |title=Effect of artificial dawn light on cardiovascular function, alertness, and balance in middle-aged and older adults. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32307533 |keywords=* aging * alertness * balance * blood pressure * heart rate * heart rate variability * light * sleep inertia |full-text-url=https://sci-hub.do/10.1093/sleep/zsaa082 }} {{medline-entry |title=Heart Rate Performance Curve Is Dependent on Age, Sex, and Performance. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32300582 |keywords=* aging * heart rate deflection * intensity prescription * maximal heart rate * sex differences * ß1-receptor sensitivity |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144539 }} {{medline-entry |title=Physical activity trajectories, mortality, hospitalization, and disability in the Toledo Study of Healthy Aging. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32163233 |keywords=* Adverse outcomes * Healthy aging * Mortality * Older adults * Physical activity * Trajectories |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432572 }} {{medline-entry |title=U-Shaped Association of Plasma Testosterone, and no Association of Plasma Estradiol, with Incidence of Fractures in Men. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32155267 |keywords=* estradiol * fracture * male aging * osteoporosis * sex hormone-binding globulin * testosterone |full-text-url=https://sci-hub.do/10.1210/clinem/dgaa115 }} {{medline-entry |title=Pregnancy-Related Bone Mineral and Microarchitecture Changes in Women Aged 30 to 45 Years. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32119748 |keywords=* AGING * ANALYSIS/QUANTITATION OF BONE * BONE QCT/μCT * EPIDEMIOLOGY * GENERAL POPULATION STUDIES |full-text-url=https://sci-hub.do/10.1002/jbmr.3998 }} {{medline-entry |title=Analysis of the world record time for combined father and son marathon. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31917623 |keywords=* V̇o2max * aerobic exercise * aging * endurance * oxygen consumption * running |full-text-url=https://sci-hub.do/10.1152/japplphysiol.00819.2019 }} {{medline-entry |title=Age-related reductions in heart rate variability do not worsen during exposure to humid compared to dry heat: A secondary analysis. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31934605 |keywords=* Aging * autonomic nervous system * heat stress * parasympathetic nervous system * relative humidity * sympathetic nervous system |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949029 }} {{medline-entry |title=Efficacy and Safety of Dapagliflozin in the Elderly: Analysis From the DECLARE-TIMI 58 Study. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31843945 |mesh-terms=* Adult * Age Factors * Aged * Aged, 80 and over * Aging * Benzhydryl Compounds * Cardiovascular System * Diabetes Mellitus, Type 2 * Diabetic Ketoacidosis * Female * Glucosides * Humans * Hypoglycemia * Hypoglycemic Agents * Incidence * Kidney * Male * Middle Aged * Sodium-Glucose Transporter 2 Inhibitors * Survival Analysis * Treatment Outcome * Urinary Tract Infections |full-text-url=https://sci-hub.do/10.2337/dc19-1476 }} {{medline-entry |title=Validity of Prediction Equations of Maximal Heart Rate in Physically Active Female Adolescents and the Role of Maturation. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31766291 |mesh-terms=* Adolescent * Aging * Body Mass Index * Exercise * Exercise Test * Female * Heart Rate * Humans |keywords=* cardiac rate * exercise prescription * exercise testing * prediction equations * training zones * volleyball |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915545 }} {{medline-entry |title=Base excision repair but not DNA double-strand break repair is impaired in aged human adipose-derived stem cells. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31782607 |mesh-terms=* Adipose Tissue * Adult * Aging * DNA Breaks, Double-Stranded * DNA End-Joining Repair * DNA Repair * Humans * Middle Aged * Recombinational DNA Repair * Stem Cells * Up-Regulation * X-ray Repair Cross Complementing Protein 1 * Young Adult |keywords=* XRCC1 * adipose-derived stem cells * base excision repair * genome integrity * human aging |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996963 }} {{medline-entry |title=Urban-Rural Differences in Hip Fracture Mortality: A Nationwide NOREPOS Study. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31768493 |keywords=* AGING * EPIDEMIOLOGY * GENERAL POPULATION STUDIES * OSTEOPOROSIS * STATISTICAL METHODS |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874178 }} {{medline-entry |title=Malnutrition as a Strong Predictor of the Onset of Sarcopenia. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31783482 |mesh-terms=* Aged * Aging * Cohort Studies * Female * Humans * Independent Living * Male * Malnutrition * Proportional Hazards Models * Prospective Studies * Risk Factors * Sarcopenia |keywords=* EWGSOP2 * GLIM * SarcoPhAge * malnutrition * sarcopenia |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950107 }} {{medline-entry |title=Acclimation to a thermoneutral environment abolishes age-associated alterations in heart rate and heart rate variability in conscious, unrestrained mice. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31776883 |keywords=* Aging * Cardiac autonomic modulation * Heart rate * Heart rate variability * Thermoneutrality |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031176 }} {{medline-entry |title=Long-term dementia risk prediction by the LIBRA score: A 30-year follow-up of the CAIDE study. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31736136 |mesh-terms=* Aged * Apolipoproteins E * Cognitive Dysfunction * Dementia * Female * Follow-Up Studies * Genetic Predisposition to Disease * Humans * Life Style * Male * Protective Factors * Risk Assessment * Risk Factors |keywords=* cognitive aging * cohort study * dementia * epidemiology * lifestyle * prevention * risk factors |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003764 }} {{medline-entry |title=Kidney function and its association to imminent, short- and long-term fracture risk-a longitudinal study in older women. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31754754 |keywords=* Aging * Bone mineral density * Chronic kidney disease * Estimated glomerular filtration rate * Fracture * Women |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946753 }} {{medline-entry |title=Oxidatively Damaged DNA/RNA and 8-Isoprostane Levels Are Associated With the Development of Type 2 Diabetes at Older Age: Results From a Large Cohort Study. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31653645 |mesh-terms=* Age of Onset * Aged * Aging * Biomarkers * Cohort Studies * DNA * DNA Damage * Diabetes Mellitus, Type 2 * Dinoprost * Female * Follow-Up Studies * Germany * Humans * Incidence * Lipid Peroxidation * Male * Middle Aged * Oxidation-Reduction * Oxidative Stress * RNA |full-text-url=https://sci-hub.do/10.2337/dc19-1379 }} {{medline-entry |title=Associations of vigorous physical activity with all-cause, cardiovascular and cancer mortality among 64 913 adults. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31548909 |keywords=* cardio-protection * exercise * longevity * non-communicable diseases * physical activity |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733336 }} {{medline-entry |title=Reduced cerebrovascular and cardioventilatory responses to intermittent hypoxia in elderly. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31557538 |mesh-terms=* Adult * Aged * Aging * Blood Pressure * Brain * Cerebrovascular Circulation * Female * Heart Rate * Humans * Hypoxia * Male * Pulmonary Ventilation * Ultrasonography, Doppler, Transcranial * Young Adult |keywords=* Aging * Arterial oxygen saturation * Cerebral blood flow * Cerebral tissue oxygenation * Heart rate * Hypoxemia * Ventilation |full-text-url=https://sci-hub.do/10.1016/j.resp.2019.103306 }} {{medline-entry |title=Vestibulo-sympathetic reflex in patients with bilateral vestibular loss. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31513442 |mesh-terms=* Aging * Bilateral Vestibulopathy * Female * Humans * Male * Middle Aged * Reflex, Abnormal * Sympathetic Nervous System |keywords=* bilateral vestibular loss * compensation * multisensory integration * otolithic system * vestibulo-sympathetic reflex |full-text-url=https://sci-hub.do/10.1152/japplphysiol.00466.2019 }} {{medline-entry |title=Heart rate and blood pressure in male Ts65Dn mice: a model to investigate cardiovascular responses in Down syndrome. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31496136 |mesh-terms=* Animals * Autonomic Nervous System * Blood Pressure * Circadian Rhythm * Down Syndrome * Heart Rate * Male * Mice * Mice, Inbred C57BL * Vascular Stiffness |keywords=* Aging * arterial stiffness * autonomic nervous system * circadian * pulse wave velocity * spectral analysis |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732568 }} {{medline-entry |title=Body weight at 10 years of age and change in body composition between 8 and 10 years of age were related to survival in a longitudinal study of 39 Labrador retriever dogs. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31500653 |mesh-terms=* Adipose Tissue * Animals * Body Composition * Body Weight * Dogs * Longevity * Longitudinal Studies * Survival Analysis |keywords=* Cohort * Cox * DEXA * Dogs * Fat mass * Healthspan * Lean mass * Lean to fat ratio * Longevity * Sarcopenia |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734441 }} {{medline-entry |title=Dietary diversity offsets the adverse mortality risk among older indigenous Taiwanese. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31464406 |mesh-terms=* Aged * Aged, 80 and over * Asian Continental Ancestry Group * Diet * Female * Health Surveys * Humans * Indigenous Peoples * Longevity * Male * Mortality * Nutrition Surveys * Nutritional Status * Risk Factors * Taiwan |full-text-url=https://sci-hub.do/10.6133/apjcn.201909_28(3).0019 }} {{medline-entry |title=Independent and joint effects of vascular and cardiometabolic risk factor pairs for risk of all-cause dementia: a prospective population-based study. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31455442 |mesh-terms=* Aged * Aged, 80 and over * Aging * Apolipoprotein E4 * Cognitive Dysfunction * Dementia * Exercise * Female * Heart Failure * Heterozygote * Humans * Hypertension * Male * Pennsylvania * Proportional Hazards Models * Prospective Studies * Risk Factors * Stroke |keywords=* Alzheimer‘s disease (AD) * apolipoprotein E (APOE) * cerebral vascular disease (CVD) * dementia * epidemiology |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948010 }} {{medline-entry |title=Work Ability and Job Survival: Four-Year Follow-Up. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31466415 |mesh-terms=* Adult * Brazil * Employment * Female * Follow-Up Studies * Hospitals * Humans * Male * Proportional Hazards Models * Work Capacity Evaluation |keywords=* aging * healthcare worker * life course * longitudinal studies * prolonged work career * work ability |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747402 }} {{medline-entry |title=Predictivity of bioimpedance phase angle for incident disability in older adults. |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31436391 |keywords=* Aging * Body composition * Cellular health * Muscle mass * Nutrition |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015240 }}
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