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Aging genes 30-59
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==MYC== * {{medline-title |title=Enhanced proliferative capacity of human preadipocytes achieved by an optimized cultivating method that induces transient activity of hTERT. |date=20.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32703451 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.06.019 }} * {{medline-title |title=Collaboration of [[MYC]] and [[RUNX2]] in lymphoma simulates T-cell receptor signaling and attenuates p53 pathway activity. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31257681 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772115 }} * {{medline-title |title=Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes. |date=13.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31200451 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627600 }} * {{medline-title |title=Transcriptomic analysis of human IL-7 receptor alpha and effector memory CD8 T cells reveals an age-associated signature linked to influenza vaccine response in older adults. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31044512 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612637 }} * {{medline-title |title=[[SLC1A5]] glutamine transporter is a target of [[MYC]] and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30909319 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516164 }} * {{medline-title |title=Profound, durable and [[MGMT]]-independent sensitivity of glioblastoma cells to cyclin-dependent kinase inhibition. |date=01.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30549269 |full-text-url=https://sci-hub.do/10.1002/ijc.32069 }} * {{medline-title |title=[[MYC]] and RAS are unable to cooperate in overcoming cellular senescence and apoptosis in normal human fibroblasts. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526305 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343716 }} * {{medline-title |title=A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation. |date=02.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279449 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168501 }} * {{medline-title |title=O-GlcNAcylation is required for mutant [[KRAS]]-induced lung tumorigenesis. |date=01.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30130254 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205381 }} * {{medline-title |title=Centenarians Overexpress Pluripotency-Related Genes. |date=16.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797 |full-text-url=https://sci-hub.do/10.1093/gerona/gly168 }} * {{medline-title |title=E47 Governs the [[MYC]]-CDKN1B/p27 -RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16 and Wild-Type p53. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003124 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039985 }} * {{medline-title |title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201 }} * {{medline-title |title=[[MYC]] Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition. |date=10.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29641997 |full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.03.057 }} * {{medline-title |title=Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage- and Histone Methylation-Dependent Pathways. |date=27.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29590617 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915310 }} * {{medline-title |title=Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older adults. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29383869 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847877 }} * {{medline-title |title=Modulation of dietary folate with age confers selective hepatocellular epigenetic imprints through DNA methylation. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29220669 |full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2017.10.007 }} * {{medline-title |title=Proline Metabolism in Cell Regulation and Cancer Biology: Recent Advances and Hypotheses. |date=01.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28990419 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338564 }} * {{medline-title |title=[[MYC]] Modulation around the CDK2/p27/SKP2 Axis. |date=30.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28665315 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541307 }} * {{medline-title |title=Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts. |date=01.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28635509 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576272 }} * {{medline-title |title=Nickel-induced HIF-1α promotes growth arrest and senescence in normal human cells but lacks toxic effects in transformed cells. |date=15.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28552779 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568485 }} * {{medline-title |title=Role of p16 and BMI-1 in oxidative stress-induced premature senescence in human dental pulp stem cells. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28410532 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390672 }} * {{medline-title |title=The RUNX Genes as Conditional Oncogenes: Insights from Retroviral Targeting and Mouse Models. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28299662 |full-text-url=https://sci-hub.do/10.1007/978-981-10-3233-2_16 }} * {{medline-title |title=Protection against High-Fat-Diet-Induced Obesity in [[MDM2]] Mice Due to Reduced p53 Activity and Enhanced Energy Expenditure. |date=24.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28122227 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560502 }} * {{medline-title |title=Downregulation of [[CITED2]] contributes to TGFβ-mediated senescence of tendon-derived stem cells. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28084522 |full-text-url=https://sci-hub.do/10.1007/s00441-016-2552-1 }} * {{medline-title |title=[[STAT3]]-mediated [[SMAD3]] activation underlies Oncostatin M-induced Senescence. |date=16.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27892764 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324753 }} * {{medline-title |title=Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans. |date=15.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27654940 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157077 }} * {{medline-title |title=Bromodomain and Extraterminal Protein Inhibition Blocks Growth of Triple-negative Breast Cancers through the Suppression of Aurora Kinases. |date=04.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27650498 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095428 }} * {{medline-title |title=Mitochondrial function in hypoxic ischemic injury and influence of aging. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27321753 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161736 }} * {{medline-title |title=JAZ7 negatively regulates dark-induced leaf senescence in Arabidopsis. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26547795 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737072 }} * {{medline-title |title=ARF: connecting senescence and innate immunity for clearance. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26412380 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600620 }} * {{medline-title |title=Reduced expression of [[MYC]] increases longevity and enhances healthspan. |date=29.01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25619689 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624921 }} * {{medline-title |title=Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25485586 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613853 }} * {{medline-title |title=DNA and RNA quadruplex-binding proteins. |date=29.09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25268620 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227175 }} * {{medline-title |title=Aging and injury: alterations in cellular energetics and organ function. |date=04.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24729935 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966668 }} * {{medline-title |title=[[PLA2R1]]: expression and function in cancer. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24667060 |full-text-url=https://sci-hub.do/10.1016/j.bbcan.2014.03.003 }} * {{medline-title |title=Senescence-secreted factors activate Myc and sensitize pretransformed cells to TRAIL-induced apoptosis. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24589226 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326894 }}
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