Редактирование: Whole brain emulation (раздел)

==== Geometric Adjustment ====

Various methods are being developed to automatically correct the image stack so that they match best. The simplest method is finding a combination of translation, scaling and rotation that works best. However, this runs the risk of over-matching.

Human brain and rat stacks have been corrected with good results using an elastic model to correct distortion by <ref>Schmitt O, Modersitzki J, Heldmann S, Wirtz S, and Fischer B. "Image registration of sectioned brains". ''International Journal of Computer Vision'', 73: 5‐39, 2007.</ref>.