Редактирование:
Aging genes 20-29
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==GHR== * {{medline-title |title=Tissue-Specific [[GHR]] Knockout Mice: An Updated Review. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33162937 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581730 }} * {{medline-title |title=Data mining of human plasma proteins generates a multitude of highly predictive aging clocks that reflect different aspects of aging. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33031577 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681068 }} * {{medline-title |title=Muscle-dependent regulation of adipose tissue function in long-lived growth hormone-mutant mice. |date=28.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32464603 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288969 }} * {{medline-title |title=The mir-465 family is upregulated with age and attenuates growth hormone signaling in mouse liver. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637918 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413667 }} * {{medline-title |title=Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30503129 |full-text-url=https://sci-hub.do/10.1016/j.fertnstert.2018.08.018 }} * {{medline-title |title=Effects of rapamycin on growth hormone receptor knockout mice. |date=13.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29378959 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816183 }} * {{medline-title |title=Disruption of the GH receptor gene in adult mice and in insulin sensitive tissues. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29198419 |full-text-url=https://sci-hub.do/10.1016/j.ghir.2017.11.003 }} * {{medline-title |title=The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28630896 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473676 }} * {{medline-title |title=Differential effects of early-life nutrient restriction in long-lived [[GHR]]-KO and normal mice. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28523599 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505892 }} * {{medline-title |title=Brain Structure and Function Associated with Younger Adults in Growth Hormone Receptor-Deficient Humans. |date=15.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28073935 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320603 }} * {{medline-title |title=Enhanced Cognition and Hypoglutamatergic Signaling in a Growth Hormone Receptor Knockout Mouse Model of Successful Aging. |date=01.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27208894 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410893 }} * {{medline-title |title=Growth hormone receptor expression in human gluteal versus abdominal subcutaneous adipose tissue: Association with body shape. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27015877 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084456 }} * {{medline-title |title=The somatotropic axis and aging: Benefits of endocrine defects. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26925766 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792645 }} * {{medline-title |title=Growth factors, aging and age-related diseases. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26883276 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455771 }} * {{medline-title |title=Correlation Analysis Between Expression Levels of Hepatic Growth Hormone Receptor, Janus Kinase 2, Insulin-Like Growth Factor-I Genes and Dwarfism Phenotype in Bama Minipig. |date=02.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26353733 |full-text-url=https://sci-hub.do/10.1166/jnn.2015.9001 }} * {{medline-title |title=Growth hormone modulates hypothalamic inflammation in long-lived pituitary dwarf mice. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26268661 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693470 }} * {{medline-title |title=Removal of growth hormone receptor ([[GHR]]) in muscle of male mice replicates some of the health benefits seen in global [[GHR]]-/- mice. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26233957 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543039 }} * {{medline-title |title=Gene expression of key regulators of mitochondrial biogenesis is sex dependent in mice with growth hormone receptor deletion in liver. |date=03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25855408 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394730 }} * {{medline-title |title=Interaction of growth hormone receptor/binding protein gene disruption and caloric restriction for insulin sensitivity and attenuated aging. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25789159 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358413 }} * {{medline-title |title=Inflammatory and Glutamatergic Homeostasis Are Involved in Successful Aging. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25711529 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864157 }} * {{medline-title |title=Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted ([[GHR]]-KO) mice attenuates phenotypic features of slow aging. |date=12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25244225 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326932 }} * {{medline-title |title=Molecular evolution of growth hormone and insulin-like growth factor 1 receptors in long-lived, small-bodied mammals. |date=10.10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25065922 |full-text-url=https://sci-hub.do/10.1016/j.gene.2014.07.061 }} * {{medline-title |title=Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population. |date=04.03.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24606898 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988204 }} * {{medline-title |title=Expression of apoptosis-related genes in liver-specific growth hormone receptor gene-disrupted mice is sex dependent. |date=01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24550353 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296163 }} * {{medline-title |title=Direct and indirect effects of growth hormone receptor ablation on liver expression of xenobiotic metabolizing genes. |date=15.10.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23941873 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798695 }} * {{medline-title |title=The slow-aging growth hormone receptor/binding protein gene-disrupted ([[GHR]]-KO) mouse is protected from aging-resultant neuromusculoskeletal frailty. |date=02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23824747 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889906 }} * {{medline-title |title=A dwarf mouse model with decreased GH/IGF-1 activity that does not experience life-span extension: potential impact of increased adiposity, leptin, and insulin with advancing age. |date=02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23695394 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038240 }} * {{medline-title |title=B16/F10 tumors in aged 3D collagen in vitro simulate tumor growth and gene expression in aged mice in vivo. |date=06.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23661088 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838284 }} * {{medline-title |title=Metabolic characteristics of long-lived mice. |date=2012 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23248643 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521393 }}
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