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Aging genes 30-39
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==KL== * {{medline-title |title=Alignment of Alzheimer's disease amyloid β-peptide and klotho. |date=11-12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32999998 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521834 }} * {{medline-title |title=PTSD and the klotho longevity gene: Evaluation of longitudinal effects on inflammation via DNA methylation. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32438247 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293549 }} * {{medline-title |title=Epigenetic Regulation of [[KL]] (Klotho) via H3K27me3 (Histone 3 Lysine [K] 27 Trimethylation) in Renal Tubule Cells. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32223380 |full-text-url=https://sci-hub.do/10.1161/HYPERTENSIONAHA.120.14642 }} * {{medline-title |title=[[FGF23]] expression is stimulated in transgenic α-Klotho longevity mouse model. |date=05.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31801907 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962016 }} * {{medline-title |title=The goddess who spins the thread of life: Klotho, psychiatric stress, and accelerated aging. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872092 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660403 }} * {{medline-title |title=[i][[KL]]OTHO[/i] heterozygosity attenuates [i]APOE4[/i]-related amyloid burden in preclinical AD. |date=16.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30867273 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550504 }} * {{medline-title |title=Utilizing Atlas-Based Modeling to Predict Knee Joint Cartilage Degeneration: Data from the Osteoarthritis Initiative. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30547410 |full-text-url=https://sci-hub.do/10.1007/s10439-018-02184-y }} * {{medline-title |title=Impaired proteostasis in senescent vascular endothelial cells: a perspective on estrogen and oxidative stress in the aging vasculature. |date=01.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30499713 |full-text-url=https://sci-hub.do/10.1152/ajpheart.00318.2018 }} * {{medline-title |title=Leukocyte Telomere Length in Patients with Radiographic Knee Osteoarthritis. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30488497 |full-text-url=https://sci-hub.do/10.1002/em.22247 }} * {{medline-title |title=Klotho at the Edge of Alzheimer's Disease and Senile Depression. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29978424 |full-text-url=https://sci-hub.do/10.1007/s12035-018-1200-z }} * {{medline-title |title=Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29890178 |full-text-url=https://sci-hub.do/10.1016/j.mad.2018.06.002 }} * {{medline-title |title=G-395A polymorphism in the promoter region of the [[KL]]OTHO gene associates with frailty among the oldest-old. |date=30.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29712948 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928057 }} * {{medline-title |title=Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of [[RIG]]-I/NF-κB Signaling. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29403373 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778393 }} * {{medline-title |title=Changes in expression of klotho affect physiological processes, diseases, and cancer. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433 }} * {{medline-title |title=Anti-aging factor, serum alpha-Klotho, as a marker of acute physiological stress, and a predictor of ICU mortality, in patients with septic shock. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29268200 |full-text-url=https://sci-hub.do/10.1016/j.jcrc.2017.11.023 }} * {{medline-title |title=Secreted αKlotho isoform protects against age-dependent memory deficits. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29086766 |full-text-url=https://sci-hub.do/10.1038/mp.2017.211 }} * {{medline-title |title=Induction of anti-aging gene klotho with a small chemical compound that demethylates CpG islands. |date=18.07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28657902 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564520 }} * {{medline-title |title=Longevity Klotho gene polymorphism and the risk of dementia in older men. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28539162 |full-text-url=https://sci-hub.do/10.1016/j.maturitas.2017.04.005 }} * {{medline-title |title=Klotho, APOEε4, cognitive ability, brain size, atrophy, and survival: a study in the Aberdeen Birth Cohort of 1936. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28431289 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.02.019 }} * {{medline-title |title=The relevance of α-[[KL]]OTHO to the central nervous system: Some key questions. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28323064 |full-text-url=https://sci-hub.do/10.1016/j.arr.2017.03.003 }} * {{medline-title |title=Systemic klotho is associated with [[KL]]OTHO variation and predicts intrinsic cortical connectivity in healthy human aging. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27714549 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382127 }} * {{medline-title |title=Activation of [[SIRT1]] Attenuates Klotho Deficiency-Induced Arterial Stiffness and Hypertension by Enhancing AMP-Activated Protein Kinase Activity. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27620389 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063709 }} * {{medline-title |title=The [[FGF23]]/[[KL]]OTHO Regulatory Network and Its Roles in Human Disorders. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27125741 |full-text-url=https://sci-hub.do/10.1016/bs.vh.2016.02.001 }} * {{medline-title |title=Antiaging Gene Klotho Deficiency Promoted High-Fat Diet-Induced Arterial Stiffening via Inactivation of AMP-Activated Protein Kinase. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26781278 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752379 }} * {{medline-title |title=[[KL]]-optimal experimental design for discriminating between two growth models applied to a beef farm. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26776261 |full-text-url=https://sci-hub.do/10.3934/mbe.2016.13.67 }} * {{medline-title |title=Secreted and Transmembrane αKlotho Isoforms Have Different Spatio-Temporal Profiles in the Brain during Aging and Alzheimer's Disease Progression. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26599613 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658185 }} * {{medline-title |title=Genetic Variants in [[KL]]OTHO Associate With Cognitive Function in the Oldest Old Group. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26405063 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978356 }} * {{medline-title |title=Molecular basis of Klotho: from gene to function in aging. |date=04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25695404 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399270 }} * {{medline-title |title=Life extension factor klotho enhances cognition. |date=22.05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24813892 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176932 }} * {{medline-title |title=Quadriceps intramuscular fat fraction rather than muscle size is associated with knee osteoarthritis. |date=02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24361743 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932784 }} * {{medline-title |title=Biochemical and functional characterization of the klotho-VS polymorphism implicated in aging and disease risk. |date=20.12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24217253 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868745 }} * {{medline-title |title=Association of Klotho polymorphisms with healthy aging: a systematic review and meta-analysis. |date=04.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24164579 |full-text-url=https://sci-hub.do/10.1089/rej.2013.1523 }} * {{medline-title |title=Serum [[KL]]-6 concentrations are associated with molecular sizes and efflux behavior of [[KL]]-6/[[MUC1]] in healthy subjects. |date=23.09.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23778023 |full-text-url=https://sci-hub.do/10.1016/j.cca.2013.06.002 }}
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