Редактирование:
Aging genes 300
(раздел)
Перейти к навигации
Перейти к поиску
Внимание:
Вы не вошли в систему. Ваш IP-адрес будет общедоступен, если вы запишете какие-либо изменения. Если вы
войдёте
или
создадите учётную запись
, её имя будет использоваться вместо IP-адреса, наряду с другими преимуществами.
Анти-спам проверка.
Не
заполняйте это!
==SIRT1== * {{medline-title |title=[[SIRT1]] - a new mammalian substrate of nuclear autophagy. |date=08.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33292048 |full-text-url=https://sci-hub.do/10.1080/15548627.2020.1860541 }} * {{medline-title |title=The Aging Stress Response and Its Implication for AMD Pathogenesis. |date=22.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33266495 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700335 }} * {{medline-title |title=Anthocyanins attenuate endothelial dysfunction through regulation of uncoupling of nitric oxide synthase in aged rats. |date=03.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33274583 |full-text-url=https://sci-hub.do/10.1111/acel.13279 }} * {{medline-title |title=Sirtuins and Their Implications in Neurodegenerative Diseases from a Drug Discovery Perspective. |date=05.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33280374 |full-text-url=https://sci-hub.do/10.1021/acschemneuro.0c00696 }} * {{medline-title |title=Naringenin alleviates nonalcoholic steatohepatitis in middle-aged Apoe mice: role of [[SIRT1]]. |date=18.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33234364 |full-text-url=https://sci-hub.do/10.1016/j.phymed.2020.153412 }} * {{medline-title |title=Effects of alpha-mangostin on memory senescence induced by high glucose in human umbilical vein endothelial cells. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33149857 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585532 }} * {{medline-title |title=Melatonin and Sirtuins in Buccal Epithelium: Potential Biomarkers of Aging and Age-Related Pathologies. |date=30.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143333 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662974 }} * {{medline-title |title=[[SIRT1]] Activation Using CRISPR/dCas9 Promotes Regeneration of Human Corneal Endothelial Cells through Inhibiting Senescence. |date=04.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33158256 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694272 }} * {{medline-title |title=Histone Deacetylase [[SIRT1]], Smooth Muscle Cell Function, and Vascular Diseases. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33117155 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573826 }} * {{medline-title |title=6,4'-dihydroxy-7-methoxyflavanone protects against H O -induced cellular senescence by inducing [[SIRT1]] and inhibiting phosphatidylinositol 3-kinase/Akt pathway activation. |date=27.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33111210 |full-text-url=https://sci-hub.do/10.1007/s11010-020-03951-z }} * {{medline-title |title=Sirtuins as Possible Predictors of Aging and Alzheimer's Disease Development: Verification in the Hippocampus and Saliva. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33098511 |full-text-url=https://sci-hub.do/10.1007/s10517-020-04986-4 }} * {{medline-title |title=[[FGFR4]] Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer. |date=14.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066597 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602396 }} * {{medline-title |title=A comparative study on the cellular stressors in mesenchymal stem cells (MSCs) and pancreatic β-cells under hyperglycemic milieu. |date=30.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32997307 |full-text-url=https://sci-hub.do/10.1007/s11010-020-03922-4 }} * {{medline-title |title=[i]Citrus hystrix[/i] Extracts Protect Human Neuronal Cells against High Glucose-Induced Senescence. |date=30.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33007805 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600454 }} * {{medline-title |title=Isoparvifuran isolated from Dalbergia odorifera attenuates H O -induced senescence of BJ cells through [[SIRT1]] activation and AKT/mTOR pathway inhibition. |date=30.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33010892 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.09.096 }} * {{medline-title |title=[[SIRT1]] Is the Target Gene for 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside Alleviating the HUVEC Senescence. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013385 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508177 }} * {{medline-title |title=Re-equilibration of imbalanced NAD metabolism ameliorates the impact of telomere dysfunction. |date=02.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32935380 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604620 }} * {{medline-title |title=The Role of Sirtuins in Kidney Diseases. |date=12.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32932720 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555196 }} * {{medline-title |title=The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32919015 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111090 }} * {{medline-title |title=Senescence and autophagy in usual interstitial pneumonia of different etiology. |date=27.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32851507 |full-text-url=https://sci-hub.do/10.1007/s00428-020-02917-2 }} * {{medline-title |title=Virus-Induced Asthma Exacerbations: [[SIRT1]] Targeted Approach. |date=13.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32823491 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464235 }} * {{medline-title |title=Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32793997 |full-text-url=https://sci-hub.do/10.1007/s10522-020-09896-6 }} * {{medline-title |title=Glucose restriction delays senescence and promotes proliferation of HUVECs via the AMPK/[[SIRT1]]-[[FOXA3]]-Beclin1 pathway. |date=01.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32768436 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111053 }} * {{medline-title |title=Ginsenoside Rg1 protects against Sca-1 HSC/HPC cell aging by regulating the [[SIRT1]]-[[FOXO3]] and [[SIRT3]]-[[SOD2]] signaling pathways in a γ-ray irradiation-induced aging mice model. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32765665 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388550 }} * {{medline-title |title=Therapeutic Effects of SRT2104 on Lung Injury in Rats with Emphysema via Reduction of Type II Alveolar Epithelial Cell Senescence. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32722945 |full-text-url=https://sci-hub.do/10.1080/15412555.2020.1797657 }} * {{medline-title |title=Quercetin alleviates kidney fibrosis by reducing renal tubular epithelial cell senescence through the [[SIRT1]]/PINK1/mitophagy axis. |date=15.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32702447 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118116 }} * {{medline-title |title=[[SIRT1]] alleviates high-magnitude compression-induced senescence in nucleus pulposus cells via [[PINK1]]-dependent mitophagy. |date=18.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32687063 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485741 }} * {{medline-title |title=Survival analyses in Holstein cows considering direct disease diagnoses and specific SNP marker effects. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32684467 |full-text-url=https://sci-hub.do/10.3168/jds.2020-18174 }} * {{medline-title |title=Material basis, effect, and mechanism of ethanol extract of Pinellia ternata tubers on oxidative stress-induced cell senescence. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32659678 |full-text-url=https://sci-hub.do/10.1016/j.phymed.2020.153275 }} * {{medline-title |title=Inhibition of miR-34a reduces cellular senescence in human adipose tissue-derived mesenchymal stem cells through the activation of [[SIRT1]]. |date=15.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32634429 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118055 }} * {{medline-title |title=Transcriptome analysis of common and diverged circulating miRNAs between arterial and venous during aging. |date=30.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32609094 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377886 }} * {{medline-title |title=Activation of FoxO1/[[SIRT1]]/RANKL/OPG pathway may underlie the therapeutic effects of resveratrol on aging-dependent male osteoporosis. |date=12.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32532246 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293127 }} * {{medline-title |title=Latifolin Inhibits Oxidative Stress-Induced Senescence via Upregulation of [[SIRT1]] in Human Dermal Fibroblasts. |date=01.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32404543 |full-text-url=https://sci-hub.do/10.1248/bpb.b20-00094 }} * {{medline-title |title=Metabolite Profiling of Rambutan ([i]Nephelium lappaceum[/i] L.) Seeds Using UPLC-qTOF-MS/MS and Senomorphic Effects in Aged Human Dermal Fibroblasts. |date=15.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32429147 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284571 }} * {{medline-title |title=SRT1720-induced activation of [[SIRT1]] alleviates vascular smooth muscle cell senescence through PKA-dependent phosphorylation of AMPKα at Ser485. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32421926 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327920 }} * {{medline-title |title=Circadian rhythm disruption and Alzheimer's disease: The dynamics of a vicious cycle. |date=28.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32348224 |full-text-url=https://sci-hub.do/10.2174/1570159X18666200429013041 }} * {{medline-title |title=miR-128 plays a critical role in murine osteoclastogenesis and estrogen deficiency-induced bone loss. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32292498 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150474 }} * {{medline-title |title=Lymphocyte senescence in COPD is associated with decreased sirtuin 1 expression in steroid resistant pro-inflammatory lymphocytes. |date=01-12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32270742 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153179 }} * {{medline-title |title=Therapeutic effects of hydro-alcoholic leaf extract of Withania somnifera on age-induced changes in daily rhythms of Sirt1, Nrf2 and Rev-erbα in the SCN of male Wistar rats. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32249404 |full-text-url=https://sci-hub.do/10.1007/s10522-020-09875-x }} * {{medline-title |title=Dipeptidyl peptidase-4 inhibition improves endothelial senescence by activating AMPK/[[SIRT1]]/Nrf2 signaling pathway. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32251672 |full-text-url=https://sci-hub.do/10.1016/j.bcp.2020.113951 }} * {{medline-title |title=The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32214805 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084123 }} * {{medline-title |title=Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32158519 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048230 }} * {{medline-title |title=Spatiotemporal gating of [[SIRT1]] functions by O-GlcNAcylation is essential for liver metabolic switching and prevents hyperglycemia. |date=24.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32152092 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104039 }} * {{medline-title |title=Hydrogen Sulfide Inhibits Homocysteine-Induced Neuronal Senescence by Up-Regulation of [[SIRT1]]. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32132865 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053352 }} * {{medline-title |title=[[SIRT1]] and aging related signaling pathways. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32084459 |full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111215 }} * {{medline-title |title=Tropisetron protects against brain aging via attenuating oxidative stress, apoptosis and inflammation: The role of [[SIRT1]] signaling. |date=01.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32088214 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.117452 }} * {{medline-title |title=Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of [[SIRT1]] activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32056076 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206476 }} * {{medline-title |title=The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of [[SIRT1]]. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32047577 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003265 }} * {{medline-title |title=Deacetylation of MRTF-A by [[SIRT1]] defies senescence induced down-regulation of collagen type I in fibroblast cells. |date=01.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32061777 |full-text-url=https://sci-hub.do/10.1016/j.bbadis.2020.165723 }} * {{medline-title |title=Chronic Polyphenon-60 or Catechin Treatments Increase Brain Monoamines Syntheses and Hippocampal [[SIRT1]] Levels Improving Cognition in Aged Rats. |date=26.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31991916 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071257 }} * {{medline-title |title=Context-Dependent Roles for [[SIRT2]] and [[SIRT3]] in Tumor Development Upon Calorie Restriction or High Fat Diet. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31970087 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960403 }} * {{medline-title |title=Duck Oil-loaded Nanoemulsion Inhibits Senescence of Angiotensin II-treated Vascular Smooth Muscle Cells by Upregulating [[SIRT1]]. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31970335 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957441 }} * {{medline-title |title=Two novel [[SIRT1]] activators, SCIC2 and SCIC2.1, enhance [[SIRT1]]-mediated effects in stress response and senescence. |date=06-07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31942817 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574383 }} * {{medline-title |title=Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1. |date=23.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31881011 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949053 }} * {{medline-title |title=The protective role of omentin-1 in IL-1β-induced chondrocyte senescence. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31852248 |full-text-url=https://sci-hub.do/10.1080/21691401.2019.1699803 }} * {{medline-title |title=The Lifespan Extension Ability of Nicotinic Acid Depends on Whether the Intracellular NAD Level Is Lower than the Sirtuin-Saturating Concentrations. |date=24.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31878234 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982340 }} * {{medline-title |title=Alpha-mangostin decreased cellular senescence in human umbilical vein endothelial cells. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31792920 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214571 }} * {{medline-title |title=Central nervous system [[SIRT1]] expression is required for cued and contextual fear conditioning memory responses in aging mice. |date=23.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31763496 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839599 }} * {{medline-title |title=Does education level protect us from rapid ageing? Sirtuin expression versus age and level of education. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31785216 }} * {{medline-title |title=CO ameliorates endothelial senescence induced by 5-fluorouracil through [[SIRT1]] activation. |date=30.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31704100 |full-text-url=https://sci-hub.do/10.1016/j.abb.2019.108185 }} * {{medline-title |title=Long noncoding RNA GAS5 inhibits cell proliferation and fibrosis in diabetic nephropathy by sponging miR-221 and modulating [[SIRT1]] expression. |date=20.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31631065 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834398 }} * {{medline-title |title=[[NLRP3]] inflammasome suppression improves longevity and prevents cardiac aging in male mice. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31625260 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974709 }} * {{medline-title |title=The Role of Sirtuin1 in Regulating Endothelial Function, Arterial Remodeling and Vascular Aging. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31572218 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751260 }} * {{medline-title |title=Deacetylation of [[LAMP1]] drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31544977 |full-text-url=https://sci-hub.do/10.1002/jcp.29182 }} * {{medline-title |title=Plasma exosomes in OSA patients promote endothelial senescence: effect of long-term adherent continuous positive airway pressure. |date=13.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31552414 |full-text-url=https://sci-hub.do/10.1093/sleep/zsz217 }} * {{medline-title |title=Metabolism and biochemical properties of nicotinamide adenine dinucleotide (NAD) analogs, nicotinamide guanine dinucleotide (NGD) and nicotinamide hypoxanthine dinucleotide (NHD). |date=11.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31511627 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739475 }} * {{medline-title |title=Hydrogen Sulfide Inhibits High Glucose-Induced Neuronal Senescence by Improving Autophagic Flux [i]via[/i] Up-regulation of [[SIRT1]]. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31481873 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710442 }} * {{medline-title |title=MicroRNA-34a (miR-34a) Mediates Retinal Endothelial Cell Premature Senescence through Mitochondrial Dysfunction and Loss of Antioxidant Activities. |date=22.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31443378 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769710 }} * {{medline-title |title=Activation of the miR-34a-Mediated [[SIRT1]]/mTOR Signaling Pathway by Urolithin A Attenuates D-Galactose-Induced Brain Aging in Mice. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31420820 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985387 }} * {{medline-title |title=[Ginsenoside Rg_1 induces leukemia stem cell senescence via [[SIRT1]]/TSC_2 signal axis]. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31359662 |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20190218.002 }} * {{medline-title |title=miR-23b-3p regulates apoptosis and autophagy via suppressing [[SIRT1]] in lens epithelial cells. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31338869 |full-text-url=https://sci-hub.do/10.1002/jcb.29270 }} * {{medline-title |title=Genetic background, epigenetic factors and dietary interventions which influence human longevity. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31309340 |full-text-url=https://sci-hub.do/10.1007/s10522-019-09824-3 }} * {{medline-title |title=Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298565 |full-text-url=https://sci-hub.do/10.1089/cell.2019.0010 }} * {{medline-title |title=Interference with the bromodomain epigenome readers drives p21 expression and tumor senescence. |date=01.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31265875 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159039 }} * {{medline-title |title=Involvement of [i]microRNA-34a[/i] in Age-Related Susceptibility to Oxidative Stress in ARPE-19 Cells by Targeting the Silent Mating Type Information Regulation 2 Homolog 1/p66shc Pathway: Implications for Age-Related Macular Degeneration. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31249522 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584679 }} * {{medline-title |title=[[GPR39]] agonist TC-G 1008 ameliorates IL-1β-induced chondrocyte senescence. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31237151 |full-text-url=https://sci-hub.do/10.1080/21691401.2019.1626405 }} * {{medline-title |title=Rational design of novel sirtuin 1 activators via structure-activity insights from application of QSAR modeling. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31217784 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558509 }} * {{medline-title |title=Metformin prevents murine ovarian aging. |date=10.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182682 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594816 }} * {{medline-title |title=Time-restricted feeding delays the emergence of the age-associated, neoplastic-prone tissue landscape. |date=12.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188781 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594823 }} * {{medline-title |title=Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/[[SIRT1]] pathway. |date=10.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182679 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594820 }} * {{medline-title |title=[[SIRT1]] protects cochlear hair cell and delays age-related hearing loss via autophagy. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31170533 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.04.003 }} * {{medline-title |title=Transcriptome analysis revealed potential mechanisms of differences in physiological stress responses between caged male and female magpies. |date=03.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31159743 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547487 }} * {{medline-title |title=Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31144244 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885080 }} * {{medline-title |title=Molecular docking analysis of imine stilbene analogs and evaluation of their anti-aging activity using yeast and mammalian cell models. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31132911 |full-text-url=https://sci-hub.do/10.1080/10799893.2019.1605529 }} * {{medline-title |title=Molecular and Cellular Characterization of [[SIRT1]] Allosteric Activators. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31087296 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567996 }} * {{medline-title |title=Total flavonoids from the Carya cathayensis Sarg. leaves inhibit HUVEC senescence through the miR-34a/[[SIRT1]] pathway. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31106472 |full-text-url=https://sci-hub.do/10.1002/jcb.28986 }} * {{medline-title |title=Impaired [[SIRT1]] activity leads to diminution in glomerular endowment without accelerating age-associated GFR decline. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31087539 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513772 }} * {{medline-title |title=Estrogen-[[SIRT1]] Axis Plays a Pivotal Role in Protecting Arteries Against Menopause-Induced Senescence and Atherosclerosis. |date=01.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31105126 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976724 }} * {{medline-title |title=Spatio-temporal expression profile of sirtuins during aging of the annual fish Nothobranchius furzeri. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31075496 |full-text-url=https://sci-hub.do/10.1016/j.gep.2019.05.001 }} * {{medline-title |title=Protective effect of vildagliptin on [[TNF]]-α-induced chondrocyte senescence. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026379 |full-text-url=https://sci-hub.do/10.1002/iub.2049 }} * {{medline-title |title=Polymorphism rs7895833 in the [[SIRT1]] gene and its association with dyslipidaemia in the elderly. |date=07-08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31040057 |full-text-url=https://sci-hub.do/10.1016/j.regg.2019.01.008 }} * {{medline-title |title=Modulation of miR-34a/[[SIRT1]] signaling protects cochlear hair cells against oxidative stress and delays age-related hearing loss through coordinated regulation of mitophagy and mitochondrial biogenesis. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026620 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.03.013 }} * {{medline-title |title=Nicotinamide mononucleotide promotes osteogenesis and reduces adipogenesis by regulating mesenchymal stromal cells via the [[SIRT1]] pathway in aged bone marrow. |date=18.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31000692 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472410 }} * {{medline-title |title=Cordycepin, an Active Constituent of Nutrient Powerhouse and Potential Medicinal Mushroom [i]Cordyceps militaris[/i] Linn., Ameliorates Age-Related Testicular Dysfunction in Rats. |date=23.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31018574 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520895 }} * {{medline-title |title=The resistant effect of [[SIRT1]] in oxidative stress-induced senescence of rat nucleus pulposus cell is regulated by Akt-FoxO1 pathway. |date=31.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30967498 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509061 }} * {{medline-title |title=Photobiomodulation and Coenzyme Q Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30983970 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434313 }} * {{medline-title |title=The role of [[SIRT1]] in neuroinflammation and cognitive dysfunction in aged rats after anesthesia and surgery. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30972182 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456566 }} * {{medline-title |title=NAD supplementation rejuvenates aged gut adult stem cells. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30917412 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516145 }} * {{medline-title |title=[[NMNAT2]]-mediated NAD generation is essential for quality control of aged oocytes. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30909324 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516161 }} * {{medline-title |title=Mitochondrial dysfunction in neurodegenerative diseases and the potential countermeasure. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30889315 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566063 }} * {{medline-title |title=Drugs targeting [[SIRT1]], a new generation of therapeutics for osteoporosis and other bone related disorders? |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862606 |full-text-url=https://sci-hub.do/10.1016/j.phrs.2019.03.007 }} * {{medline-title |title=Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks. |date=11.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862067 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429360 }} * {{medline-title |title=Knockout of receptor for advanced glycation end-products attenuates age-related renal lesions. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30794349 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413655 }} * {{medline-title |title=Stress-induced precocious aging in PD-patient iPSC-derived NSCs may underlie the pathophysiology of Parkinson's disease. |date=04.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30718471 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362163 }} * {{medline-title |title=Bone Marrow Mesenchymal Stem Cells-Derived Exosomal MiR-29b-3p Regulates Aging-Associated Insulin Resistance. |date=26.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30715852 |full-text-url=https://sci-hub.do/10.1021/acsnano.8b09375 }} * {{medline-title |title=Strength training and aerobic exercise alter mitochondrial parameters in brown adipose tissue and equally reduce body adiposity in aged rats. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30712161 |full-text-url=https://sci-hub.do/10.1007/s13105-019-00663-x }} * {{medline-title |title=Novel biomolecules of ageing, sex differences and potential underlying mechanisms of telomere shortening in coronary artery disease. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30684534 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.020 }} * {{medline-title |title=Generation of a novel model of primary human cell senescence through Tenovin-6 mediated inhibition of sirtuins. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30666570 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535423 }} * {{medline-title |title=Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30659954 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.016 }} * {{medline-title |title=Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism. |date=23.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30673631 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366955 }} * {{medline-title |title=Protective Role of Endogenous Kallistatin in Vascular Injury and Senescence by Inhibiting Oxidative Stress and Inflammation. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30622668 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304815 }} * {{medline-title |title=NKT-like cells reveal higher than T lymphocytes expression of cellular protective proteins HSP70 and [[SOD2]] and comparably increased expression of [[SIRT1]] in the oldest seniors. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30633320 |full-text-url=https://sci-hub.do/10.5603/FHC.a2018.0025 }} * {{medline-title |title=Melatonin regulates the activities of ovary and delays the fertility decline in female animals via MT1/AMPK pathway. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30597622 |full-text-url=https://sci-hub.do/10.1111/jpi.12550 }} * {{medline-title |title=Exercise training augments Sirt1-signaling and attenuates cardiac inflammation in D-galactose induced-aging rats. |date=23.12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30582744 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326662 }} * {{medline-title |title=Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30537739 |full-text-url=https://sci-hub.do/10.1159/000495895 }} * {{medline-title |title=Diesel exhaust exposure intensifies inflammatory and structural changes associated with lung aging in mice. |date=15.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30530184 |full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.11.139 }} * {{medline-title |title=CD56bright cells respond to stimulation until very advanced age revealing increased expression of cellular protective proteins [[SIRT1]], HSP70 and [[SOD2]]. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30534181 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262966 }} * {{medline-title |title=Amentoflavone Induces Autophagy and Modulates p53. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30507085 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275431 }} * {{medline-title |title=Induction of a senescent like phenotype and loss of gap junctional intercellular communication by carbon nanoparticle exposure of lung epithelial cells. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30476532 |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.017 }} * {{medline-title |title=Sirtuins: Developing Innovative Treatments for Aged-Related Memory Loss and Alzheimer's Disease. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30484407 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538488 }} * {{medline-title |title=N-acetylcysteine ameliorates cisplatin-induced renal senescence and renal interstitial fibrosis through sirtuin1 activation and p53 deacetylation. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30447351 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.11.006 }} * {{medline-title |title=Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice. |date=20.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463018 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296764 }} * {{medline-title |title=Metformin Is a Direct [[SIRT1]]-Activating Compound: Computational Modeling and Experimental Validation. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30459716 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232372 }} * {{medline-title |title=Hsp90 Stabilizes [[SIRT1]] Orthologs in Mammalian Cells and [i]C. elegans[/i]. |date=20.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463299 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274930 }} * {{medline-title |title=Sirtuins and NAD in the Development and Treatment of Metabolic and Cardiovascular Diseases. |date=14.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30355082 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206880 }} * {{medline-title |title=[[SIRT1]] deacetylase in aging-induced neuromuscular degeneration and amyotrophic lateral sclerosis. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30295421 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260920 }} * {{medline-title |title=Prevention of Senescence in Vasculature Through Quiescence. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30259779 |full-text-url=https://sci-hub.do/10.1089/rej.2018.2138 }} * {{medline-title |title=Melatonin and inflammation-Story of a double-edged blade. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30242884 |full-text-url=https://sci-hub.do/10.1111/jpi.12525 }} * {{medline-title |title=[[ALDH2]] mediates the dose-response protection of chronic ethanol against endothelial senescence through [[SIRT1]]/p53 pathway. |date=12.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217444 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.08.081 }} * {{medline-title |title=Resveratrol-loaded nanoemulsion prevents cognitive decline after abdominal surgery in aged rats. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30196020 |full-text-url=https://sci-hub.do/10.1016/j.jphs.2018.08.006 }} * {{medline-title |title=Endothelial [[SIRT1]] prevents age-induced impairment of vasodilator responses by enhancing the expression and activity of soluble guanylyl cyclase in smooth muscle cells. |date=01.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30165439 |full-text-url=https://sci-hub.do/10.1093/cvr/cvy212 }} * {{medline-title |title=Effects of Ginsenoside Rg3 on fatigue resistance and [[SIRT1]] in aged rats. |date=01.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30144466 |full-text-url=https://sci-hub.do/10.1016/j.tox.2018.08.010 }} * {{medline-title |title=[[PARP1]] inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD levels and increasing [[SIRT1]] activity. |date=23.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30139380 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107962 }} * {{medline-title |title=Moderate calorie restriction attenuates age‑associated alterations and improves cardiac function by increasing [[SIRT1]] and [[SIRT3]] expression. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30132522 |full-text-url=https://sci-hub.do/10.3892/mmr.2018.9390 }} * {{medline-title |title=Liver regeneration in aged mice: new insights. |date=28.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30157472 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128415 }} * {{medline-title |title=Phenolic Plant Extracts Induce Sirt1 Activity and Increase Antioxidant Levels in the Rabbit's Heart and Liver. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30116475 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079382 }} * {{medline-title |title=Defect of [[SIRT1]]-FoxO3a axis is associated with the production of reactive oxygen species during protein kinase CK2 downregulation-mediated cellular senescence and nematode aging. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30103847 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507845 }} * {{medline-title |title=Master athletes have higher miR-7, [[SIRT3]] and [[SOD2]] expression in skeletal muscle than age-matched sedentary controls. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30107294 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092475 }} * {{medline-title |title=Tenovin-1 Induces Senescence and Decreases Wound-Healing Activity in Cultured Rat Primary Astrocytes. |date=01.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30092626 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513186 }} * {{medline-title |title=[[PGC]]-1α Protects [[RPE]] Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis. |date=07.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30087287 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121367 }} * {{medline-title |title=Effect of oral appliance on circulating leukocyte telomere length and [[SIRT1]] in obstructive sleep apnea. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30030618 |full-text-url=https://sci-hub.do/10.1007/s00784-018-2560-5 }} * {{medline-title |title=miR-34a Promotes Vascular Smooth Muscle Cell Calcification by Downregulating [[SIRT1]] (Sirtuin 1) and Axl (AXL Receptor Tyrosine Kinase). |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30026277 |full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.311298 }} * {{medline-title |title=A [[SIRT1]]-centered circuitry regulates breast cancer stemness and metastasis. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30038266 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283862 }} * {{medline-title |title=Apelin/APJ axis improves angiotensin II-induced endothelial cell senescence through AMPK/[[SIRT1]] signaling pathway. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30002688 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040122 }} * {{medline-title |title=Sirtuin 1 and Alzheimer's disease: An up-to-date review. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30007474 |full-text-url=https://sci-hub.do/10.1016/j.npep.2018.07.001 }} * {{medline-title |title=CCAR-1 is a negative regulator of the heat-shock response in Caenorhabditis elegans. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003683 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156500 }} * {{medline-title |title=Kallistatin attenuates endothelial senescence by modulating Let-7g-mediated miR-34a-[[SIRT1]]-eNOS pathway. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29992759 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111868 }} * {{medline-title |title=Serum containing Buyang Huanwu decoction prevents age-associated migration and invasion of human vascular smooth muscle cells by up regulating [[SIRT1]] expression. |date=17.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29952352 |full-text-url=https://sci-hub.do/10.5582/bst.2018.01063 }} * {{medline-title |title=Role of accelerated aging in limb muscle wasting of patients with COPD. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29970961 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022820 }} * {{medline-title |title=Resveratrol promotes oxidative stress to drive [[DLC1]] mediated cellular senescence in cancer cells. |date=15.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29964052 |full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.06.031 }} * {{medline-title |title=Mesenchymal stem cells confer resistance to doxorubicin-induced cardiac senescence by inhibiting microRNA-34a. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29928373 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004710 }} * {{medline-title |title=The circadian clock in adult neural stem cell maintenance. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29886147 |full-text-url=https://sci-hub.do/10.1016/j.pneurobio.2018.05.007 }} * {{medline-title |title=Resveratrol reduces senescence-associated secretory phenotype by [[SIRT1]]/NF-κB pathway in gut of the annual fish Nothobranchius guentheri. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29908321 |full-text-url=https://sci-hub.do/10.1016/j.fsi.2018.06.027 }} * {{medline-title |title=Loss of [[NAMPT]] in aging retinal pigment epithelium reduces NAD availability and promotes cellular senescence. |date=12.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905535 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046249 }} * {{medline-title |title=Mushroom extract inhibits ultraviolet B-induced cellular senescence in human keratinocytes. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29860669 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021292 }} * {{medline-title |title=[[SIRT1]], miR-132 and miR-212 link human longevity to Alzheimer's Disease. |date=31.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29855513 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981646 }} * {{medline-title |title=Endothelial progenitor cells from aged subjects display decreased expression of sirtuin 1, angiogenic functions, and increased senescence. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29851177 |full-text-url=https://sci-hub.do/10.1002/cbin.10999 }} * {{medline-title |title=Rejuvenating Aged Hematopoietic Stem Cells Through Improvement of Mitochondrial Function. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29797808 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973912 }} * {{medline-title |title=Berberine Improves Cognitive Deficiency and Muscular Dysfunction via Activation of the AMPK/[[SIRT1]]/[[PGC]]-1a Pathway in Skeletal Muscle from Naturally Aging Rats. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29806860 |full-text-url=https://sci-hub.do/10.1007/s12603-018-1015-7 }} * {{medline-title |title=[[SIRT1]] reverses senescence via enhancing autophagy and attenuates oxidative stress-induced apoptosis through promoting p53 degradation. |date=01.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29803744 |full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2018.05.174 }} * {{medline-title |title=Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774638 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052398 }} * {{medline-title |title=Dietary polyphenols and neurogenesis: Molecular interactions and implication for brain ageing and cognition. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29753753 |full-text-url=https://sci-hub.do/10.1016/j.neubiorev.2018.05.011 }} * {{medline-title |title=Whey Protein Attenuates Angiotensin II-Primed Premature Senescence of Vascular Smooth Muscle Cells through Upregulation of [[SIRT1]]. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29725214 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932937 }} * {{medline-title |title=Role of hypothalamus in aging and its underlying cellular mechanisms. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29729230 |full-text-url=https://sci-hub.do/10.1016/j.mad.2018.04.008 }} * {{medline-title |title=The variable role of [[SIRT1]] in the maintenance and differentiation of mesenchymal stem cells. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29715067 |full-text-url=https://sci-hub.do/10.2217/rme-2017-0128 }} * {{medline-title |title=Sirtuins in Renal Health and Disease. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29712732 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050939 }} * {{medline-title |title=Physical Exercise Improves Aging-Related Changes in Angiotensin, IGF-1, [[SIRT1]], [[SIRT3]], and VEGF in the Substantia Nigra. |date=10.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659739 |full-text-url=https://sci-hub.do/10.1093/gerona/gly072 }} * {{medline-title |title=MeCP2-mediated epigenetic regulation in senescent endothelial progenitor cells. |date=03.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615114 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883541 }} * {{medline-title |title=Natural products with anti-aging potential: Affected targets and molecular mechanisms. |date=01.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29597027 |full-text-url=https://sci-hub.do/10.1016/j.biotechadv.2018.03.012 }} * {{medline-title |title=[Effect of microRNA-34a/[[SIRT1]]/p53 signal pathway on notoginsenoside R₁ delaying vascular endothelial cell senescence]. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29600625 |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180110.001 }} * {{medline-title |title=[[SIRT1]] and microRNAs: The role in breast, lung and prostate cancers. |date=01.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29574020 |full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.03.023 }} * {{medline-title |title=Leukotriene D4 induces cellular senescence in osteoblasts. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29587204 |full-text-url=https://sci-hub.do/10.1016/j.intimp.2017.12.027 }} * {{medline-title |title=Impairment of an Endothelial NAD -H S Signaling Network Is a Reversible Cause of Vascular Aging. |date=22.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570999 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884172 }} * {{medline-title |title=Differential gene expression of sirtuins between somatotropinomas and nonfunctioning pituitary adenomas. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29564694 |full-text-url=https://sci-hub.do/10.1007/s11102-018-0881-7 }} * {{medline-title |title=Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice. |date=06.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29514072 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854409 }} * {{medline-title |title=Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29476819 |full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.004 }} * {{medline-title |title=[[HGF]] and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the [[SIRT1]]/[[FOXO1]] Signaling Pathway. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29462806 |full-text-url=https://sci-hub.do/10.1159/000487559 }} * {{medline-title |title=The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29407880 |full-text-url=https://sci-hub.do/10.1016/j.atherosclerosis.2018.01.043 }} * {{medline-title |title=Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29366775 |full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.01.018 }} * {{medline-title |title=Antagonism of cysteinyl leukotriene receptor 1 (cysLTR1) by montelukast suppresses cell senescence of chondrocytes. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29331588 |full-text-url=https://sci-hub.do/10.1016/j.cyto.2017.12.021 }} * {{medline-title |title=Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress. |date=20.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325896 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.01.007 }} * {{medline-title |title=Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury. |date=11.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29326403 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811244 }} * {{medline-title |title=Acetylshikonin from Zicao attenuates cognitive impairment and hippocampus senescence in d-galactose-induced aging mouse model via upregulating the expression of [[SIRT1]]. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325995 |full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2018.01.007 }} * {{medline-title |title=Dexamethasone downregulates [[SIRT1]] and [[IL6]] and upregulates [[EDN1]] genes in stem cells derived from gingivae via the AGE/RAGE pathway. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29302812 |full-text-url=https://sci-hub.do/10.1007/s10529-017-2493-0 }} * {{medline-title |title=Sirtuins in Brain Aging and Neurological Disorders. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29283326 |full-text-url=https://sci-hub.do/10.1615/CritRevEukaryotGeneExpr.2017019532 }} * {{medline-title |title=[Aging-related change of erectile function and the expression of [[SIRT1]]]. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29282911 }} * {{medline-title |title=Expression of Sirtuins in the Retinal Neurons of Mice, Rats, and Humans. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29249955 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715387 }} * {{medline-title |title=Maternal aging affects oocyte resilience to carbonyl cyanide-m-chlorophenylhydrazone -induced mitochondrial dysfunction in cows. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29182624 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705080 }} * {{medline-title |title=Nicotinamide phosphoribosyltransferase delays cellular senescence by upregulating [[SIRT1]] activity and antioxidant gene expression in mouse cells. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29178516 |full-text-url=https://sci-hub.do/10.1111/gtc.12542 }} * {{medline-title |title=Stem Cells and Progenitors in Human Peripheral Blood Get Activated by Extremely Active Resveratrol (XAR™). |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177909 |full-text-url=https://sci-hub.do/10.1007/s12015-017-9784-7 }} * {{medline-title |title=Fibroblast growth factor 21 delayed endothelial replicative senescence and protected cells from H O -induced premature senescence through [[SIRT1]]. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29118911 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666058 }} * {{medline-title |title=Tucum-do-Cerrado (Bactris setosa Mart.) May Promote Anti-Aging Effect by Upregulating [[SIRT1]]-Nrf2 Pathway and Attenuating Oxidative Stress and Inflammation. |date=14.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135935 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707715 }} * {{medline-title |title=Maternal high calorie diet induces mitochondrial dysfunction and senescence phenotype in subcutaneous fat of newborn mice. |date=13.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29137352 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663524 }} * {{medline-title |title=O-GlcNAcylation of [[SIRT1]] enhances its deacetylase activity and promotes cytoprotection under stress. |date=14.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29133780 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684413 }} * {{medline-title |title=Aging as an Epigenetic Phenomenon. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081695 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635645 }} * {{medline-title |title=MeCP2 mediated dysfunction in senescent EPCs. |date=03.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29108229 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667962 }} * {{medline-title |title=Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063982 |full-text-url=https://sci-hub.do/10.1007/s10571-017-0557-2 }} * {{medline-title |title=A comparative study of anti-aging properties and mechanism: resveratrol and caloric restriction. |date=12.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29029466 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630366 }} * {{medline-title |title=Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence. |date=17.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29041897 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645932 }} * {{medline-title |title=Negative regulation of Sirtuin 1 by AMP-activated protein kinase promotes metformin-induced senescence in hepatocellular carcinoma xenografts. |date=28.12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28964787 |full-text-url=https://sci-hub.do/10.1016/j.canlet.2017.09.027 }} * {{medline-title |title=Blocking [[SIRT1]] inhibits cell proliferation and promotes aging through the PI3K/AKT pathway. |date=01.12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28962864 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2017.09.037 }} * {{medline-title |title=[[SIRT1]] is a positive regulator of in vivo bone mass and a therapeutic target for osteoporosis. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28937996 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609767 }} * {{medline-title |title=[Protective effect of total saponins of Panax notoginseng combined with total flavonoids of epimedium on D-galactose-incuced senescence of H9c2 cell]. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28952264 |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.2017.0012 }} * {{medline-title |title=[[SIRT1]] is a transcriptional enhancer of the glucocorticoid receptor acting independently to its deacetylase activity. |date=05.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28923345 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756502 }} * {{medline-title |title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. |date=15.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352 }} * {{medline-title |title=The effect of exercise, resveratrol or their combination on Sarcopenia in aged rats via regulation of AMPK/Sirt1 pathway. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847722 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.032 }} * {{medline-title |title=Chronic Silymarin, Quercetin and Naringenin Treatments Increase Monoamines Synthesis and Hippocampal Sirt1 Levels Improving Cognition in Aged Rats. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28808887 |full-text-url=https://sci-hub.do/10.1007/s11481-017-9759-0 }} * {{medline-title |title=Aquatide Activation of [[SIRT1]] Reduces Cellular Senescence through a [[SIRT1]]-[[FOXO1]]-Autophagy Axis. |date=01.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28822991 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590795 }} * {{medline-title |title=Obesity and aging diminish sirtuin 1 ([[SIRT1]])-mediated deacetylation of [[SIRT3]], leading to hyperacetylation and decreased activity and stability of [[SIRT3]]. |date=20.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28808064 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655509 }} * {{medline-title |title=Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging. |date=10.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28802039 |full-text-url=https://sci-hub.do/10.1016/j.cell.2017.07.042 }} * {{medline-title |title=High glucose and free fatty acids induce endothelial progenitor cell senescence via [[PGC]]-1α/[[SIRT1]] signaling pathway. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28786152 |full-text-url=https://sci-hub.do/10.1002/cbin.10833 }} * {{medline-title |title=Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28767699 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540417 }} * {{medline-title |title=Comparing the Effects of Melatonin with Caloric Restriction in the Hippocampus of Aging Mice: Involvement of Sirtuin1 and the FOXOs Pathway. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28770437 |full-text-url=https://sci-hub.do/10.1007/s11064-017-2369-7 }} * {{medline-title |title=Role of Kallistatin Treatment in Aging and Cancer by Modulating miR-34a and miR-21 Expression. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28744338 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506461 }} * {{medline-title |title=Inflammation, Stem Cells, and the Aging Hypothalamus. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28756738 |full-text-url=https://sci-hub.do/10.1089/rej.2017.2002 }} * {{medline-title |title=Myricetin improves endurance capacity and mitochondrial density by activating [[SIRT1]] and [[PGC]]-1α. |date=24.07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28740165 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524912 }} * {{medline-title |title=Moving to the Rhythm with Clock (Circadian) Genes, Autophagy, mTOR, and [[SIRT1]] in Degenerative Disease and Cancer. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28721811 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600856 }} * {{medline-title |title=The emerging role of alternative splicing in senescence and aging. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28703423 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595669 }} * {{medline-title |title=miR-34a and miR-9 are overexpressed and SIRT genes are downregulated in peripheral blood mononuclear cells of aging humans. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28699360 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544174 }} * {{medline-title |title=Regulation of [[SIRT1]]/AMPK axis is critically involved in gallotannin-induced senescence and impaired autophagy leading to cell death in hepatocellular carcinoma cells. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676953 |full-text-url=https://sci-hub.do/10.1007/s00204-017-2021-y }} * {{medline-title |title=[[SIRT1]] and [[SIRT6]] Signaling Pathways in Cardiovascular Disease Protection. |date=10.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28661724 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824538 }} * {{medline-title |title=Effects of Resveratrol and other Polyphenols on Sirt1: Relevance to Brain Function During Aging. |date=30.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676015 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883375 }} * {{medline-title |title=Reduction in podocyte [[SIRT1]] accelerates kidney injury in aging mice. |date=01.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28615249 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625108 }} * {{medline-title |title=Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs. |date=12.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28611316 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509453 }} * {{medline-title |title=Ursolic Acid Mediates Hepatic Protection through Enhancing of anti-aging Biomarkers. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28558631 |full-text-url=https://sci-hub.do/10.2174/1874609810666170531103140 }} * {{medline-title |title=The NAD /[[PARP1]]/[[SIRT1]] Axis in Aging. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28537485 |full-text-url=https://sci-hub.do/10.1089/rej.2017.1980 }} * {{medline-title |title=Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28552621 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581719 }} * {{medline-title |title=Kallistatin reduces vascular senescence and aging by regulating microRNA-34a-[[SIRT1]] pathway. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28544111 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506400 }} * {{medline-title |title=Bushen-Yizhi formula ameliorates cognitive dysfunction through [[SIRT1]]/ER stress pathway in SAMP8 mice. |date=25.07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28521305 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564772 }} * {{medline-title |title=Caveolin-1 deficiency induces premature senescence with mitochondrial dysfunction. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28514055 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506423 }} * {{medline-title |title=Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-[[FOXO1]] pathway. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28507478 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427465 }} * {{medline-title |title=Steroidogenesis decline accompanied with reduced antioxidation and endoplasmic reticulum stress in mice testes during ageing. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28488286 |full-text-url=https://sci-hub.do/10.1111/and.12816 }} * {{medline-title |title=Exogenous nicotinamide supplementation and moderate physical exercise can attenuate the aging process in skeletal muscle of rats. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28477081 |full-text-url=https://sci-hub.do/10.1007/s10522-017-9705-9 }} * {{medline-title |title=Caloric restriction delays early phases of carcinogenesis via effects on the tissue microenvironment. |date=30.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28415598 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482635 }} * {{medline-title |title=During yeast chronological aging resveratrol supplementation results in a short-lived phenotype Sir2-dependent. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28412652 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397018 }} * {{medline-title |title=Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts. |date=01.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28385812 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495944 }} * {{medline-title |title=Regulation of stem cell aging by [[SIRT1]] - Linking metabolic signaling to epigenetic modifications. |date=05.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28392411 |full-text-url=https://sci-hub.do/10.1016/j.mce.2017.03.031 }} * {{medline-title |title=Ampelopsin attenuates the atrophy of skeletal muscle from d-gal-induced aging rats through activating AMPK/[[SIRT1]]/PGC-1α signaling cascade. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28364603 |full-text-url=https://sci-hub.do/10.1016/j.biopha.2017.03.070 }} * {{medline-title |title=[[SIRT1]] Polymorphisms and Serum-Induced [[SIRT1]] Protein Expression in Aging and Frailty: The CHAMP Study. |date=01.07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28329314 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279142 }} * {{medline-title |title=Melatonin reverses H O -induced senescence in SH-SY5Y cells by enhancing autophagy via sirtuin 1 deacetylation of the RelA/p65 subunit of NF-κB. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28295567 |full-text-url=https://sci-hub.do/10.1111/jpi.12407 }} * {{medline-title |title=Alkylresorcinols activate [[SIRT1]] and delay ageing in Drosophila melanogaster. |date=02.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28252007 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333101 }} * {{medline-title |title=Tat-Mediated Induction of miRs-34a
Описание изменений:
Пожалуйста, учтите, что любой ваш вклад в проект «hpluswiki» может быть отредактирован или удалён другими участниками. Если вы не хотите, чтобы кто-либо изменял ваши тексты, не помещайте их сюда.
Вы также подтверждаете, что являетесь автором вносимых дополнений, или скопировали их из источника, допускающего свободное распространение и изменение своего содержимого (см.
Hpluswiki:Авторские права
).
НЕ РАЗМЕЩАЙТЕ БЕЗ РАЗРЕШЕНИЯ ОХРАНЯЕМЫЕ АВТОРСКИМ ПРАВОМ МАТЕРИАЛЫ!
Отменить
Справка по редактированию
(в новом окне)
Навигация
Персональные инструменты
Вы не представились системе
Обсуждение
Вклад
Создать учётную запись
Войти
Пространства имён
Статья
Обсуждение
русский
Просмотры
Читать
Править
История
Ещё
Навигация
Начало
Свежие правки
Случайная страница
Инструменты
Ссылки сюда
Связанные правки
Служебные страницы
Сведения о странице
Дополнительно
Как редактировать
Вики-разметка
Telegram
Вконтакте
backup