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Aging genes 30-39
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==WRN== * {{medline-title |title=The Impact of Vitamin C on Different System Models of Werner Syndrome. |date=17.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33202145 |full-text-url=https://sci-hub.do/10.1089/ars.2020.8147 }} * {{medline-title |title=[[WRN]] modulates translation by influencing nuclear mRNA export in HeLa cancer cells. |date=14.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33054770 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557079 }} * {{medline-title |title=[[MIB1]]-mediated degradation of [[WRN]] promotes cellular senescence in response to camptothecin treatment. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32652764 |full-text-url=https://sci-hub.do/10.1096/fj.202000268RRR }} * {{medline-title |title=A Case Report of Werner's Syndrome With a Novel Mutation From India. |date=08.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32528764 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282380 }} * {{medline-title |title=Evidence for premature aging in a Drosophila model of Werner syndrome. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31518666 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935377 }} * {{medline-title |title=Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31259468 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718529 }} * {{medline-title |title=Studying Werner syndrome to elucidate mechanisms and therapeutics of human aging and age-related diseases. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30666569 |full-text-url=https://sci-hub.do/10.1007/s10522-019-09798-2 }} * {{medline-title |title=Werner Syndrome Protein and DNA Replication. |date=02.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400178 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274846 }} * {{medline-title |title=A case report of Werner's syndrome with bilateral juvenile cataracts. |date=14.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30107835 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092780 }} * {{medline-title |title=Genomic instability and DNA replication defects in progeroid syndromes. |date=31.12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29936894 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000143 }} * {{medline-title |title=Nonfunctional mutant Wrn protein leads to neurological deficits, neuronal stress, microglial alteration, and immune imbalance in a mouse model of Werner syndrome. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29908963 |full-text-url=https://sci-hub.do/10.1016/j.bbi.2018.06.007 }} * {{medline-title |title=Acidic domain of [[WRN]]p is critical for autophagy and up-regulates age associated proteins. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29800817 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338341 }} * {{medline-title |title=RECQ helicase disease and related progeroid syndromes: RECQ2018 meeting. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29752965 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217841 }} * {{medline-title |title=Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29476423 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876188 }} * {{medline-title |title=Serum vitamin C levels modulate the lifespan and endoplasmic reticulum stress response pathways in mice synthesizing a nonfunctional mutant [[WRN]] protein. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452565 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998970 }} * {{medline-title |title=Werner syndrome ([[WRN]]) gene variants and their association with altered function and age-associated diseases. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29146545 |full-text-url=https://sci-hub.do/10.1016/j.arr.2017.11.003 }} * {{medline-title |title=Human RecQL4 helicase plays multifaceted roles in the genomic stability of normal and cancer cells. |date=28.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080750 |full-text-url=https://sci-hub.do/10.1016/j.canlet.2017.10.021 }} * {{medline-title |title=Recent Advances in Understanding Werner Syndrome. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29043077 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621106 }} * {{medline-title |title=Systematic analysis of DNA crosslink repair pathways during development and aging in Caenorhabditis elegans. |date=19.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28934497 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766164 }} * {{medline-title |title=The Werner Syndrome Helicase Coordinates Sequential Strand Displacement and [[FEN1]]-Mediated Flap Cleavage during Polymerase δ Elongation. |date=01.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27849570 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247617 }} * {{medline-title |title=Vitamin C alleviates aging defects in a stem cell model for Werner syndrome. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27271327 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930768 }} * {{medline-title |title=Bloom's syndrome: Why not premature aging?: A comparison of the [[BLM]] and [[WRN]] helicases. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27238185 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124422 }} * {{medline-title |title=Understanding Vascular Diseases: Lessons From Premature Aging Syndromes. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26948039 |full-text-url=https://sci-hub.do/10.1016/j.cjca.2015.12.003 }} * {{medline-title |title=Stem Cell Depletion by Global Disorganization of the H3K9me3 Epigenetic Marker in Aging. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26160351 |full-text-url=https://sci-hub.do/10.1089/rej.2015.1742 }} * {{medline-title |title=The Werner Protein Acts as a Coactivator of Nuclear Factor κB (NF-κB) on HIV-1 and Interleukin-8 (IL-8) Promoters. |date=24.07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26037922 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513100 }} * {{medline-title |title=Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging. |date=05.06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25931448 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494668 }} * {{medline-title |title=Werner Syndrome-specific induced pluripotent stem cells: recovery of telomere function by reprogramming. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25688260 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310323 }} * {{medline-title |title=Transient overexpression of Werner protein rescues starvation induced autophagy in Werner syndrome cells. |date=12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25257404 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582615 }} * {{medline-title |title=Senescence induced by [[RECQL4]] dysfunction contributes to Rothmund-Thomson syndrome features in mice. |date=15.05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24832598 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047874 }} * {{medline-title |title=Search and insights into novel genetic alterations leading to classical and atypical Werner syndrome. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24401204 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997596 }} * {{medline-title |title=Hydrogen sulfide restores a normal morphological phenotype in Werner syndrome fibroblasts, attenuates oxidative damage and modulates mTOR pathway. |date=08.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23702336 |full-text-url=https://sci-hub.do/10.1016/j.phrs.2013.04.011 }} * {{medline-title |title=Copy number variations of DNA repair genes and the age-related cataract: Jiangsu Eye Study. |date=01.02.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23329665 |full-text-url=https://sci-hub.do/10.1167/iovs.12-10948 }} * {{medline-title |title=The associations between single nucleotide polymorphisms of DNA repair genes, DNA damage, and age-related cataract: Jiangsu Eye Study. |date=01.02.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23322570 |full-text-url=https://sci-hub.do/10.1167/iovs.12-10940 }} * {{medline-title |title=Aberrant DNA methylation profiles in the premature aging disorders Hutchinson-Gilford Progeria and Werner syndrome. |date=01.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23257959 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549877 }}
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