Редактирование: Aging genes 60-99 (раздел)

==NLRP3==

* {{medline-title
|title=Innate and Adaptive Immunity in Aging and Longevity: The Foundation of Resilience.
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33269094
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673842
}}
* {{medline-title
|title=TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity.
|date=27.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33113366
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2020.108326
}}
* {{medline-title
|title=Repeated propofol exposure-induced neuronal damage and cognitive impairment in aged rats by activation of NF-κB pathway and [[NLRP3]] inflammasome.
|date=01.01.2021
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33115643
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2020.135461
}}
* {{medline-title
|title=A Small Molecule Stabilizer of the MYC G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma.
|date=13.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066043
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650714
}}
* {{medline-title
|title=Interleukin-1β Drives Cellular Senescence of Rat Astrocytes Induced by Oligomerized Amyloid β Peptide and Oxidative Stress.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013631
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493674
}}
* {{medline-title
|title=Mechanisms of [[NLRP3]] priming in inflammaging and age related diseases.
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32883606
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571497
}}
* {{medline-title
|title=Lamivudine Inhibits [i]Alu[/i] RNA-induced Retinal Pigment Epithelium Degeneration via Anti-inflammatory and Anti-senescence Activities.
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32855848
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422901
}}
* {{medline-title
|title=The [[NLRP3]] Inflammasome: Metabolic Regulation and Contribution to Inflammaging.
|date=30.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32751530
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463618
}}
* {{medline-title
|title=Aging aggravated liver ischemia and reperfusion injury by promoting STING-mediated [[NLRP3]] activation in macrophages.
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32666684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431827
}}
* {{medline-title
|title=Targeting [[NLRP3]] Inflammasome Reduces Age-Related Experimental Alveolar Bone Loss.
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32531176
|full-text-url=https://sci-hub.do/10.1177/0022034520933533
}}
* {{medline-title
|title=Korean Red Ginseng Suppresses the Expression of Oxidative Stress Response and [[NLRP3]] Inflammasome Genes in Aged C57BL/6 Mouse Ovaries.
|date=22.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32331214
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231237
}}
* {{medline-title
|title=Cepharanthine promotes the effect of dexmedetomidine on the deposition of β-amyloid in the old age of the senile dementia rat model by regulating inflammasome expression.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32337948
|full-text-url=https://sci-hub.do/10.5114/fn.2019.89855
}}
* {{medline-title
|title=Ginsenoside Rg1 ameliorates glomerular fibrosis during kidney aging by inhibiting NOX4 and [[NLRP3]] inflammasome activation in SAMP8 mice.
|date=27.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32114413
|full-text-url=https://sci-hub.do/10.1016/j.intimp.2020.106339
}}
* {{medline-title
|title=Blockade of the [[NLRP3]] inflammasome improves metabolic health and lifespan in obese mice.
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31975052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206474
}}
* {{medline-title
|title=Autophagy and [[NLRP3]] inflammasome crosstalk in neuroinflammation in aged bovine brains.
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31903559
|full-text-url=https://sci-hub.do/10.1002/jcp.29426
}}
* {{medline-title
|title=[[NLRP3]] Inflammasome Inhibition by MCC950 in Aged Mice Improves Health via Enhanced Autophagy and PPARα Activity.
|date=13.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31603987
|full-text-url=https://sci-hub.do/10.1093/gerona/glz239
}}
* {{medline-title
|title=[[NLRP3]] inflammasome suppression improves longevity and prevents cardiac aging in male mice.
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31625260
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974709
}}
* {{medline-title
|title=Reduced NRF2 expression suppresses endothelial progenitor cell function and induces senescence during aging.
|date=08.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31494646
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756903
}}
* {{medline-title
|title=Effect of Aging on Taurine Transporter (TauT) Expression in the Mouse Brain Cortex.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31468381
|full-text-url=https://sci-hub.do/10.1007/978-981-13-8023-5_1
}}
* {{medline-title
|title=Tamoxifen-induced, intestinal-specific deletion of [i]Slc5a6[/i] in adult mice leads to spontaneous inflammation: involvement of NF-κB, [[NLRP3]], and gut microbiota.
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31369292
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842991
}}
* {{medline-title
|title=Systemic inflammation impairs microglial Aβ clearance through [[NLRP3]] inflammasome.
|date=02.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31359456
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717897
}}
* {{medline-title
|title=Aging in the Syrian hamster testis: Inflammatory-oxidative status and the impact of photoperiod.
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31276778
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110649
}}
* {{medline-title
|title=[Improved effects of saponins from Panax japonicus on decline of cognitive function in natural aging rats via [[NLRP3]] inflammasome pathway].
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30989956
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180921.001
}}
* {{medline-title
|title=Lack of [[NLRP3]] Inflammasome Activation Reduces Age-Dependent Sarcopenia and Mitochondrial Dysfunction, Favoring the Prophylactic Effect of Melatonin.
|date=04.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30869745
|full-text-url=https://sci-hub.do/10.1093/gerona/glz079
}}
* {{medline-title
|title=Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks.
|date=11.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862067
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429360
}}
* {{medline-title
|title=[[NLRP3]]/IL1β inflammasome associated with the aging bladder triggers bladder dysfunction in female rats.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30720125
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423574
}}
* {{medline-title
|title=Mitochondrial Stress-Initiated Aberrant Activation of the [[NLRP3]] Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging.
|date=22.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30673616
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371804
}}
* {{medline-title
|title=Purple sweet potato color attenuated [[NLRP3]] inflammasome by inducing autophagy to delay endothelial senescence.
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585631
|full-text-url=https://sci-hub.do/10.1002/jcp.28003
}}
* {{medline-title
|title=Inhibiting the [[NLRP3]] Inflammasome With MCC950 Ameliorates Isoflurane-Induced Pyroptosis and Cognitive Impairment in Aged Mice.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30524241
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262296
}}
* {{medline-title
|title=Klotho controls the brain-immune system interface in the choroid plexus.
|date=27.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30413620
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275534
}}
* {{medline-title
|title=[[NLRP3]] inflammasome activation in inflammaging.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30268598
|full-text-url=https://sci-hub.do/10.1016/j.smim.2018.09.001
}}
* {{medline-title
|title=Melatonin and inflammation-Story of a double-edged blade.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30242884
|full-text-url=https://sci-hub.do/10.1111/jpi.12525
}}
* {{medline-title
|title=A response to readers' comments.
|date=14.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217141
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138902
}}
* {{medline-title
|title=[[NLRP3]] inflammasome-dependent pyroptosis is proposed to be involved in the mechanism of age-dependent isoflurane-induced cognitive impairment.
|date=14.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217191
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138927
}}
* {{medline-title
|title=Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30065258
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146930
}}
* {{medline-title
|title=Pro- and Anti-inflammatory Effects of High Cholesterol Diet on Aged Brain.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29896426
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988593
}}
* {{medline-title
|title=Critical role of [[NLRP3]]-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment.
|date=17.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29665808
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904978
}}
* {{medline-title
|title=Decreased [[NLRP3]] inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869149
}}
* {{medline-title
|title=AMP-Activated Protein Kinase Regulation of the [[NLRP3]] Inflammasome during Aging.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29150317
|full-text-url=https://sci-hub.do/10.1016/j.tem.2017.10.009
}}
* {{medline-title
|title=Effects of chronically increased VEGF-A on the aging heart.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29146733
|full-text-url=https://sci-hub.do/10.1096/fj.201700761RR
}}
* {{medline-title
|title=[[NLRP3]] inflammasome activation in aged macrophages is diminished during Streptococcus pneumoniae infection.
|date=01.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29097427
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900358
}}
* {{medline-title
|title=Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing.
|date=05.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28953873
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718149
}}
* {{medline-title
|title=Specific calpain inhibition protects kidney against inflammaging.
|date=14.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28808241
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556007
}}
* {{medline-title
|title=Pressor response to angiotensin II is enhanced in aged mice and associated with inflammation, vasoconstriction and oxidative stress.
|date=28.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28659507
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509458
}}
* {{medline-title
|title=The [[NLRP3]] inflammasome contributes to sarcopenia and lower muscle glycolytic potential in old mice.
|date=01.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28536183
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582883
}}
* {{medline-title
|title=Human Plasma Thioredoxin-80 Increases With Age and in ApoE  Mice Induces Inflammation, Angiogenesis, and Atherosclerosis.
|date=01.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28473446
|full-text-url=https://sci-hub.do/10.1161/CIRCULATIONAHA.117.027612
}}
* {{medline-title
|title=Metaflammation: Tissue-Specific Alterations of the [[NLRP3]] Inflammasome Platform in Metabolic Syndrome.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28403789
|full-text-url=https://sci-hub.do/10.2174/0929867324666170407123522
}}
* {{medline-title
|title=Papilloma-pseudovirus eradicates intestinal tumours and triples the lifespan of Apc  mice.
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28397782
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394268
}}
* {{medline-title
|title=β-Hydroxybutyrate Deactivates Neutrophil [[NLRP3]] Inflammasome to Relieve Gout Flares.
|date=28.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28249154
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527297
}}
* {{medline-title
|title=Vascular endothelial cells senescence is associated with NOD-like receptor family pyrin domain-containing 3 ([[NLRP3]]) inflammasome activation via reactive oxygen species (ROS)/thioredoxin-interacting protein ([[TXNIP]]) pathway.
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28064010
|full-text-url=https://sci-hub.do/10.1016/j.biocel.2017.01.001
}}
* {{medline-title
|title=Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27845246
|full-text-url=https://sci-hub.do/10.1016/j.bbalip.2016.11.003
}}
* {{medline-title
|title=Aging-Associated [[TNF]] Production Primes Inflammasome Activation and [[NLRP3]]-Related Metabolic Disturbances.
|date=01.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27566828
|full-text-url=https://sci-hub.do/10.4049/jimmunol.1501336
}}
* {{medline-title
|title=Hepatic NAD( ) deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27174364
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945761
}}
* {{medline-title
|title=Age-Dependent Susceptibility to Pulmonary Fibrosis Is Associated with [[NLRP3]] Inflammasome Activation.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26933834
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979364
}}
* {{medline-title
|title=Increased VEGF-A promotes multiple distinct aging diseases of the eye through shared pathomechanisms.
|date=01.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912740
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772957
}}
* {{medline-title
|title=Growth Hormone Receptor Deficiency Protects against Age-Related [[NLRP3]] Inflammasome Activation and Immune Senescence.
|date=23.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26876170
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992590
}}
* {{medline-title
|title=Same molecule but different expression: aging and sepsis trigger [[NLRP3]] inflammasome activation, a target of melatonin.
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26681113
|full-text-url=https://sci-hub.do/10.1111/jpi.12303
}}
* {{medline-title
|title=Nod-like receptor pyrin containing 3 ([[NLRP3]]) in the post-mortem frontal cortex from patients with bipolar disorder: A potential mediator between mitochondria and immune-activation.
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26540403
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2015.10.015
}}
* {{medline-title
|title=Gene expression of inflammasome components in peripheral blood mononuclear cells (PBMC) of vascular patients increases with age.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596365
}}
* {{medline-title
|title=A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26379247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575031
}}
* {{medline-title
|title=Purple sweet potato color inhibits endothelial premature senescence by blocking the [[NLRP3]] inflammasome.
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26164602
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2015.04.012
}}
* {{medline-title
|title=Age-related increases in amyloid beta and membrane attack complex: evidence of inflammasome activation in the rodent eye.
|date=24.06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26104676
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486438
}}
* {{medline-title
|title=A chimeric Cfh transgene leads to increased retinal oxidative stress, inflammation, and accumulation of activated subretinal microglia in mice.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26030099
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464010
}}
* {{medline-title
|title=Drivers of age-related inflammation and strategies for healthspan extension.
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25879284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400872
}}
* {{medline-title
|title=DAMPs as mediators of sterile inflammation in aging-related pathologies.
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25641058
|full-text-url=https://sci-hub.do/10.1016/j.arr.2015.01.003
}}
* {{medline-title
|title=Protective effect of telmisartan on neurovascular unit and inflammasome in stroke-resistant spontaneously hypertensive rats.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25591419
|full-text-url=https://sci-hub.do/10.1179/1743132815Y.0000000002
}}