Редактирование: Aging genes 10-29 (раздел)

==MDM2==

* {{medline-title
|title=SENEBLOC, a long non-coding RNA suppresses senescence via p53-dependent and independent mechanisms.
|date=06.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32030426
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102969
}}
* {{medline-title
|title=Disruption of Robo2-Baiap2 integrated signaling drives cystic disease.
|date=19.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31534052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795383
}}
* {{medline-title
|title=Senescence-induced immunophenotype, gene expression and electrophysiology changes in human amniocytes.
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31478614
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815807
}}
* {{medline-title
|title=Hsp90β interacts with [[MDM2]] to suppress p53-dependent senescence during skeletal muscle regeneration.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31313490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718578
}}
* {{medline-title
|title=TZAP plays an inhibitory role in the self-renewal of porcine mesenchymal stromal cells and is implicated the regulation of premature senescence via the p53 pathway.
|date=07.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30845965
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404308
}}
* {{medline-title
|title=Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells.
|date=28.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30647108
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367206
}}
* {{medline-title
|title=The SCF  ubiquitin ligase complex mediates degradation of the tumor suppressor [[FBXO31]] and thereby prevents premature cellular senescence.
|date=19.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171069
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200945
}}
* {{medline-title
|title=The Dysfunctional [[MDM2]]-p53 Axis in Adipocytes Contributes to Aging-Related Metabolic Complications by Induction of Lipodystrophy.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131393
|full-text-url=https://sci-hub.do/10.2337/db18-0684
}}
* {{medline-title
|title=Effect of [[CCNB1]] silencing on cell cycle, senescence, and apoptosis through the p53 signaling pathway in pancreatic cancer.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30069972
|full-text-url=https://sci-hub.do/10.1002/jcp.26816
}}
* {{medline-title
|title=Boosting [[ATM]] activity alleviates aging and extends lifespan in a mouse model of progeria.
|date=02.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29717979
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957528
}}
* {{medline-title
|title=Acute [[HSF1]] depletion induces cellular senescence through the [[MDM2]]-p53-p21 pathway in human diploid fibroblasts.
|date=08.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29632240
|full-text-url=https://sci-hub.do/10.1242/jcs.210724
}}
* {{medline-title
|title=Relevance of the p53-[[MDM2]] axis to aging.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29192902
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729541
}}
* {{medline-title
|title=Pomegranate peel extract attenuates D-galactose-induced oxidative stress and hearing loss by regulating PNUTS/PP1 activity in the mouse cochlea.
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28837860
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.07.007
}}
* {{medline-title
|title=Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-[[FOXO1]] pathway.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28507478
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427465
}}
* {{medline-title
|title=Monitoring p53 by [[MDM2]] and MDMX is required for endocrine pancreas development and function in a spatio-temporal manner.
|date=01.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28118981
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328981
}}
* {{medline-title
|title=Protection against High-Fat-Diet-Induced Obesity in [[MDM2]]  Mice Due to Reduced p53 Activity and Enhanced Energy Expenditure.
|date=24.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28122227
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560502
}}
* {{medline-title
|title=Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence.
|date=28.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28105936
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249001
}}
* {{medline-title
|title=Roles of [[TP53]] in determining therapeutic sensitivity, growth, cellular senescence, invasion and metastasis.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27776972
|full-text-url=https://sci-hub.do/10.1016/j.jbior.2016.10.001
}}
* {{medline-title
|title=Dynamics of ARF regulation that control senescence and cancer.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27470213
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346319
}}
* {{medline-title
|title=Breaking a paradigm: IL-6/STAT3 signaling suppresses metastatic prostate cancer upon ARF expression.
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27308625
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905394
}}
* {{medline-title
|title=Combined therapies that induce senescence and stabilize p53 block melanoma growth and prompt antitumor immune responses.
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26405565
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570092
}}
* {{medline-title
|title=BI2536--A PLK inhibitor augments paclitaxel efficacy in suppressing tamoxifen induced senescence and resistance in breast cancer cells.
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26349973
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2015.07.005
}}
* {{medline-title
|title=[[NQO1]] Stabilizes p53 in Response to Oncogene-Induced Senescence.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26078718
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466457
}}
* {{medline-title
|title=[[MDM2]] turnover and expression of [[ATR]]X determine the choice between quiescence and senescence in response to [[CDK4]] inhibition.
|date=10.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25803170
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480747
}}
* {{medline-title
|title=Senescence induction in renal carcinoma cells by Nutlin-3: a potential therapeutic strategy based on [[MDM2]] antagonism.
|date=28.10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25067787
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2014.07.024
}}
* {{medline-title
|title=Germline genetics of the p53 pathway affect longevity in a gender specific manner.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24654968
|full-text-url=https://sci-hub.do/10.2174/1874609807666140321150751
}}