Редактирование: Aging genes 60-99 (раздел)

==H2AX==

* {{medline-title
|title=Evaluation of Gamma[[H2AX]] in Buccal Cells as a Molecular Biomarker of DNA Damage in Alzheimer's Disease in the AIBL Study of Ageing.
|date=06.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32781776
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459751
}}
* {{medline-title
|title=Cisplatin-induced peripheral neuropathy is associated to neuronal senescence-like response.
|date=29.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32597980
|full-text-url=https://sci-hub.do/10.1093/neuonc/noaa151
}}
* {{medline-title
|title=Guanine Deaminase Stimulates Ultraviolet-induced Keratinocyte Senescence in Seborrhoeic Keratosis via Guanine Metabolites.
|date=06.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32215662
|full-text-url=https://sci-hub.do/10.2340/00015555-3473
}}
* {{medline-title
|title=Do BRCA1 and BRCA2 gene mutation carriers have a reduced ovarian reserve? Protocol for a prospective observational study.
|date=25.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31772111
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887091
}}
* {{medline-title
|title=Slower rates of accumulation of DNA damage in leukocytes correlate with longer lifespans across several species of birds and mammals.
|date=15.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31730540
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874430
}}
* {{medline-title
|title=Phosphoproteomic analysis reveals plant DNA damage signalling pathways with a functional role for histone [[H2AX]] phosphorylation in plant growth under genotoxic stress.
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31410901
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900162
}}
* {{medline-title
|title=Rag1 immunodeficiency-induced early aging and senescence in zebrafish are dependent on chronic inflammation and oxidative stress.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31348603
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718522
}}
* {{medline-title
|title=Are There Common Mechanisms Between the Hutchinson-Gilford Progeria Syndrome and Natural Aging?
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156709
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529819
}}
* {{medline-title
|title=Epigallocatechin-3-gallate induces telomere shortening and clastogenic damage in glioblastoma cells.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026358
|full-text-url=https://sci-hub.do/10.1002/em.22295
}}
* {{medline-title
|title=Expression of [[RNF8]] on cochlear apoptosis and aging in mice of different ages.
|date=03-Apr,.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915826

}}
* {{medline-title
|title=Mitochondrial Protection Partly Mitigates Kidney Cellular Senescence in Swine Atherosclerotic Renal Artery Stenosis.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30907989
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519989
}}
* {{medline-title
|title=Old age increases microglial senescence, exacerbates secondary neuroinflammation, and worsens neurological outcomes after acute traumatic brain injury in mice.
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30904769
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486858
}}
* {{medline-title
|title=Avenanthramide A Induces Cellular Senescence via miR-129-3p/Pirh2/p53 Signaling Pathway To Suppress Colon Cancer Growth.
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30888162
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b00833
}}
* {{medline-title
|title=PFG acted as an inducer of premature senescence in TIG-1 normal diploid fibroblast and an inhibitor of mitosis in the HeLa cells.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30836860
|full-text-url=https://sci-hub.do/10.1080/09168451.2019.1585744
}}
* {{medline-title
|title=[[S100A13]] promotes senescence-associated secretory phenotype and cellular senescence via modulation of non-classical secretion of IL-1α.
|date=23.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30670674
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366962
}}
* {{medline-title
|title=Clostridium difficile toxin B induces senescence in enteric glial cells: A potential new mechanism of Clostridium difficile pathogenesis.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30296499
|full-text-url=https://sci-hub.do/10.1016/j.bbamcr.2018.10.007
}}
* {{medline-title
|title=Varenicline reduces DNA damage, tau mislocalization and post surgical cognitive impairment in aged mice.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30273594
|full-text-url=https://sci-hub.do/10.1016/j.neuropharm.2018.09.044
}}
* {{medline-title
|title=The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30235328
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147527
}}
* {{medline-title
|title=Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187775
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180720
}}
* {{medline-title
|title=Acetylation of PGC1α by Histone Deacetylase 1 Downregulation Is Implicated in Radiation-Induced Senescence of Brain Endothelial Cells.
|date=16.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30016403
|full-text-url=https://sci-hub.do/10.1093/gerona/gly167
}}
* {{medline-title
|title=Role of accelerated aging in limb muscle wasting of patients with COPD.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29970961
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022820
}}
* {{medline-title
|title=[Protective effect of Wuzi Yanzong recipe on testicular DNA damage and apoptosis in natural ageing rats].
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29751716
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180115.005
}}
* {{medline-title
|title=Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions.
|date=04.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29249653
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756112
}}
* {{medline-title
|title=Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice.
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29141658
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688691
}}
* {{medline-title
|title=Therapeutic doses of doxorubicin induce premature senescence of human mesenchymal stem cells derived from menstrual blood, bone marrow and adipose tissue.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29022209
|full-text-url=https://sci-hub.do/10.1007/s12185-017-2346-6
}}
* {{medline-title
|title=Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice.
|date=07.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807355
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.08.035
}}
* {{medline-title
|title=The Cytolethal Distending Toxin Subunit CdtB of [i]Helicobacter hepaticus[/i] Promotes Senescence and Endoreplication in Xenograft Mouse Models of Hepatic and Intestinal Cell Lines.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28713773
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491915
}}
* {{medline-title
|title=Increased level of DNA damage in some organs of obese Zucker rats by γ-[[H2AX]] analysis.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28714549
|full-text-url=https://sci-hub.do/10.1002/em.22115
}}
* {{medline-title
|title=[The Role of DNA Double-strain Damage Repairing Mechanisms in Diabetic Atheroscolersis].
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28612525

}}
* {{medline-title
|title=DNA damage marker phosphorylated histone [[H2AX]] is a potential predictive marker for progression of epithelial dysplasia of the oral cavity.
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28543539
|full-text-url=https://sci-hub.do/10.1111/his.13260
}}
* {{medline-title
|title=Tumor stroma with senescence-associated secretory phenotype in steatohepatitic hepatocellular carcinoma.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28273155
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342190
}}
* {{medline-title
|title=Metformin alleviates ageing cellular phenotypes in Hutchinson-Gilford progeria syndrome dermal fibroblasts.
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28192606
|full-text-url=https://sci-hub.do/10.1111/exd.13323
}}
* {{medline-title
|title=Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase ([[GBA]]) and alpha-galactosidase A ([[GLA]]) enzymes.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28098348
|full-text-url=https://sci-hub.do/10.1002/jcp.25807
}}
* {{medline-title
|title=Liver damage and senescence increases in patients developing hepatocellular carcinoma.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28052383
|full-text-url=https://sci-hub.do/10.1111/jgh.13717
}}
* {{medline-title
|title=The Chromatin-Associated Phf12 Protein Maintains Nucleolar Integrity and Prevents Premature Cellular Senescence.
|date=01.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27956701
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311238
}}
* {{medline-title
|title=Axitinib induces senescence-associated cell death and necrosis in glioma cell lines: The proteasome inhibitor, bortezomib, potentiates axitinib-induced cytotoxicity in a p21(Waf/Cip1) dependent manner.
|date=10.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27926485
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356889
}}
* {{medline-title
|title=Detection of Dysfunctional Telomeres in Oncogene-Induced Senescence.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27812868
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-6670-7_6
}}
* {{medline-title
|title=Transgenic expression of cyclooxygenase-2 (COX2) causes premature aging phenotypes in mice.
|date=07.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27750221
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115895
}}
* {{medline-title
|title=Overexpression of catalase in mice reduces age-related oxidative stress and maintains sperm production.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27575890
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.08.012
}}
* {{medline-title
|title=BRCA-1 Gene Expression and Comparative Proteomic Profile of Primordial Follicles from Young and Adult Buffalo (Bubalus bubalis) Ovaries.
|date=03.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27552356
|full-text-url=https://sci-hub.do/10.1080/10495398.2016.1210613
}}
* {{medline-title
|title=In vitro model for DNA double-strand break repair analysis in breast cancer reveals cell type-specific associations with age and prognosis.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27494941
|full-text-url=https://sci-hub.do/10.1096/fj.201600453R
}}
* {{medline-title
|title=Effects of Aging and Oxidative Stress on Spermatozoa of Superoxide-Dismutase 1- and Catalase-Null Mice.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27465136
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333935
}}
* {{medline-title
|title=Growth arrest of lung carcinoma cells (A549) by polyacrylate-anchored peroxovanadate by activating Rac1-NADPH oxidase signalling axis.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27435854
|full-text-url=https://sci-hub.do/10.1007/s11010-016-2761-7
}}
* {{medline-title
|title=p53-Dependent DNA damage response sensitive to editing-defective tRNA synthetase in zebrafish.
|date=26.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27402763
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968768
}}
* {{medline-title
|title=Mesenchymal stromal cells having inactivated [[RB1]] survive following low irradiation and accumulate damaged DNA: Hints for side effects following radiotherapy.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27124644
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323029
}}
* {{medline-title
|title=The impact of autophagy on cell death modalities in CRL-5876 lung adenocarcinoma cells after their exposure to γ-rays and/or erlotinib.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27026538
|full-text-url=https://sci-hub.do/10.1007/s10565-016-9319-z
}}
* {{medline-title
|title=Dehydroleucodine inhibits tumor growth in a preclinical melanoma model by inducing cell cycle arrest, senescence and apoptosis.
|date=01.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26718258
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2015.12.004
}}
* {{medline-title
|title=SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin.
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26663487
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832318
}}
* {{medline-title
|title=Persistent γ[[H2AX]]: A promising molecular marker of DNA damage and aging.
|date=10-12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26596544
|full-text-url=https://sci-hub.do/10.1016/j.mrrev.2015.07.001
}}
* {{medline-title
|title=Axitinib induces DNA damage response leading to senescence, mitotic catastrophe, and increased NK cell recognition in human renal carcinoma cells.
|date=03.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26474283
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742174
}}
* {{medline-title
|title=Comparative proteomic analysis of primordial follicles from ovaries of immature and aged rats.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26391928
|full-text-url=https://sci-hub.do/10.3109/19396368.2015.1077903
}}
* {{medline-title
|title=Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities.
|date=18.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26240351
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547227
}}
* {{medline-title
|title=Impairing the radioresistance of cancer cells by hydrogenated nanodiamonds.
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26010122
|full-text-url=https://sci-hub.do/10.1016/j.biomaterials.2015.05.034
}}
* {{medline-title
|title=Age-related change in γ[[H2AX]] of Drosophila muscle: its significance as a marker for muscle damage and longevity.
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25860864
|full-text-url=https://sci-hub.do/10.1007/s10522-015-9573-0
}}
* {{medline-title
|title=Depletion of [[SI]]RT6 causes cellular senescence, DNA damage, and telomere dysfunction in human chondrocytes.
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25819580
|full-text-url=https://sci-hub.do/10.1016/j.joca.2015.03.024
}}
* {{medline-title
|title=Long-term arsenite exposure induces premature senescence in B cell lymphoma A20 cells.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25787150
|full-text-url=https://sci-hub.do/10.1007/s00204-015-1500-2
}}
* {{medline-title
|title=Changes in the expression of DNA double strand break repair genes in primordial follicles from immature and aged rats.
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25599822
|full-text-url=https://sci-hub.do/10.1016/j.rbmo.2014.11.010
}}
* {{medline-title
|title=Long-term Neuroglial Cocultures as a Brain Aging Model: Hallmarks of Senescence, MicroRNA Expression Profiles, and Comparison With In Vivo Models.
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25568096
|full-text-url=https://sci-hub.do/10.1093/gerona/glu231
}}
* {{medline-title
|title=Loss of Nfkb1 leads to early onset aging.
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25553648
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276787
}}
* {{medline-title
|title=Oxidative Glial Cell Damage Associated with White Matter Lesions in the Aging Human Brain.
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25311358
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861214
}}
* {{medline-title
|title=Gallotannin is a DNA damaging compound that induces senescence independently of p53 and p21 in human colon cancer cells.
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24798519
|full-text-url=https://sci-hub.do/10.1002/mc.22172
}}
* {{medline-title
|title=Oxidative DNA damage causes premature senescence in mouse embryonic fibroblasts deficient for Krüppel-like factor 4.
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24788960
|full-text-url=https://sci-hub.do/10.1002/mc.22161
}}
* {{medline-title
|title=HP1α mediates defective heterochromatin repair and accelerates senescence in Zmpste24-deficient cells.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24584199
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049960
}}
* {{medline-title
|title=Wild-type p53-induced phosphatase 1 (Wip1) forestalls cellular premature senescence at physiological oxygen levels by regulating DNA damage response signaling during DNA replication.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24552809
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984300
}}
* {{medline-title
|title=[Correlation between DNA damage and EB virus infection in nasopharyngeal carcinoma].
|date=02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24491061

}}
* {{medline-title
|title=Phosphorylation of histone [[H2AX]] in the mouse brain from development to senescence.
|date=21.01.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24451138
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907886
}}