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Aging genes 60-99
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==SIRT6== * {{medline-title |title=Association between [[SIRT6]] Methylation and Human Longevity in a Chinese Population. |date=25.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33238266 |full-text-url=https://sci-hub.do/10.1159/000508832 }} * {{medline-title |title=The [[SIRT6]] activator MDL-800 improves genomic stability and pluripotency of old murine-derived iPS cells. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33089974 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431819 }} * {{medline-title |title=Sirtuins as Possible Predictors of Aging and Alzheimer's Disease Development: Verification in the Hippocampus and Saliva. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33098511 |full-text-url=https://sci-hub.do/10.1007/s10517-020-04986-4 }} * {{medline-title |title=Age-related epigenetic drift deregulates [i][[SIRT6]][/i] expression and affects its downstream genes in human peripheral blood mononuclear cells. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32573339 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678931 }} * {{medline-title |title=Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators. |date=07.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32518153 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415977 }} * {{medline-title |title=Age-dependent role of [[SIRT6]] in jawbone via regulating senescence and autophagy of bone marrow stromal cells. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32002721 |full-text-url=https://sci-hub.do/10.1007/s10735-020-09857-w }} * {{medline-title |title=Mechanism of activation for the sirtuin 6 protein deacylase. |date=31.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31822559 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996886 }} * {{medline-title |title=Proteomics of Long-Lived Mammals. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31737995 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117992 }} * {{medline-title |title=Sirtuins and [[SIRT6]] in Carcinogenesis and in Diet. |date=07.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31591350 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801518 }} * {{medline-title |title=[[SIRT6]]-mediated transcriptional suppression of MALAT1 is a key mechanism for endothelial to mesenchymal transition. |date=15.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31399301 |full-text-url=https://sci-hub.do/10.1016/j.ijcard.2019.07.082 }} * {{medline-title |title=[[SIRT6]] Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. |date=18.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31002797 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499390 }} * {{medline-title |title=[[SIRT6]] participates in the quality control of aged oocytes via modulating telomere function. |date=29.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30926765 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503879 }} * {{medline-title |title=LINE1 Derepression in Aged Wild-Type and [[SIRT6]]-Deficient Mice Drives Inflammation. |date=02.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30853213 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449196 }} * {{medline-title |title=Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism. |date=23.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30673631 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366955 }} * {{medline-title |title=Diesel exhaust exposure intensifies inflammatory and structural changes associated with lung aging in mice. |date=15.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30530184 |full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.11.139 }} * {{medline-title |title=Phosphodiesterase 4 inhibitor activates AMPK-[[SIRT6]] pathway to prevent aging-related adipose deposition induced by metabolic disorder. |date=18.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30227388 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188481 }} * {{medline-title |title=MiR-125b attenuates human hepatocellular carcinoma malignancy through targeting [[SIRT6]]. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30034937 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048406 }} * {{medline-title |title=Role of accelerated aging in limb muscle wasting of patients with COPD. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29970961 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022820 }} * {{medline-title |title=A Review of the Recent Advances Made with [[SIRT6]] and its Implications on Aging Related Processes, Major Human Diseases, and Possible Therapeutic Targets. |date=29.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966233 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164879 }} * {{medline-title |title=Application of multivariate longitudinal models in [[SIRT6]], FBS, and BMI analysis of the elderly. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29901417 |full-text-url=https://sci-hub.do/10.1080/13685538.2018.1477933 }} * {{medline-title |title=Sirtuins in Renal Health and Disease. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29712732 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050939 }} * {{medline-title |title=Boosting [[ATM]] activity alleviates aging and extends lifespan in a mouse model of progeria. |date=02.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29717979 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957528 }} * {{medline-title |title=High expression of CPT1b in skeletal muscle in metabolically healthy older subjects. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29657112 |full-text-url=https://sci-hub.do/10.1016/j.diabet.2018.01.018 }} * {{medline-title |title=Haploinsufficiency of [i]Trp53[/i] dramatically extends the lifespan of Sirt6-deficient mice. |date=23.02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29474172 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825207 }} * {{medline-title |title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 }} * {{medline-title |title=Stem Cells and Progenitors in Human Peripheral Blood Get Activated by Extremely Active Resveratrol (XAR™). |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177909 |full-text-url=https://sci-hub.do/10.1007/s12015-017-9784-7 }} * {{medline-title |title=Aging as an Epigenetic Phenomenon. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081695 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635645 }} * {{medline-title |title=Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28767699 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540417 }} * {{medline-title |title=[[SIRT1]] and [[SIRT6]] Signaling Pathways in Cardiovascular Disease Protection. |date=10.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28661724 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824538 }} * {{medline-title |title=Ursolic Acid Mediates Hepatic Protection through Enhancing of anti-aging Biomarkers. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28558631 |full-text-url=https://sci-hub.do/10.2174/1874609810666170531103140 }} * {{medline-title |title=Characterization of physiological defects in adult [[SIRT6]]-/- mice. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28448551 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407791 }} * {{medline-title |title=Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts. |date=01.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28385812 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495944 }} * {{medline-title |title=[[SIRT6]] polymorphism rs117385980 is associated with longevity and healthy aging in Finnish men. |date=11.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28399814 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387321 }} * {{medline-title |title=Neuroprotective Functions for the Histone Deacetylase [[SIRT6]]. |date=28.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28355558 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389893 }} * {{medline-title |title=Cosmeceutical product consisting of biomimetic peptides: antiaging effects in vivo and in vitro. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28123310 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234555 }} * {{medline-title |title=Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27882448 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357501 }} * {{medline-title |title=[[SIRT6]]: Novel Mechanisms and Links to Aging and Disease. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27836583 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326594 }} * {{medline-title |title=Multiple pathways of [[SIRT6]] at the crossroads in the control of longevity, cancer, and cardiovascular diseases. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27829173 |full-text-url=https://sci-hub.do/10.1016/j.arr.2016.10.008 }} * {{medline-title |title=[[SIRT6]] delays cellular senescence by promoting p27Kip1 ubiquitin-proteasome degradation. |date=16.09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27794562 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115890 }} * {{medline-title |title=The protein-interaction network with functional roles in tumorigenesis, neurodegeneration, and aging. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27699588 |full-text-url=https://sci-hub.do/10.1007/s11010-016-2836-5 }} * {{medline-title |title=[[SIRT6]] Overexpression Improves Various Aspects of Mouse Healthspan. |date=01.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27519885 |full-text-url=https://sci-hub.do/10.1093/gerona/glw152 }} * {{medline-title |title=Slowing ageing by design: the rise of NAD and sirtuin-activating compounds. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27552971 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107309 }} * {{medline-title |title=Ursolic acid regulates aging process through enhancing of metabolic sensor proteins level. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27470332 |full-text-url=https://sci-hub.do/10.1016/j.biopha.2016.04.047 }} * {{medline-title |title=Ergothioneine oxidation in the protection against high-glucose induced endothelial senescence: Involvement of [[SIRT1]] and [[SIRT6]]. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27101740 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2016.04.013 }} * {{medline-title |title=Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins. |date=15.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27038700 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.03.015 }} * {{medline-title |title=AMPK/Snf1 signaling regulates histone acetylation: Impact on gene expression and epigenetic functions. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27010499 |full-text-url=https://sci-hub.do/10.1016/j.cellsig.2016.03.009 }} * {{medline-title |title=Calorie restriction-induced [[SIRT6]] activation delays aging by suppressing NF-κB signaling. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26940461 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889297 }} * {{medline-title |title=Sirtuins, Cell Senescence, and Vascular Aging. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26948035 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848124 }} * {{medline-title |title=Lack of association between polymorphisms in the [[SIRT6]] gene and longevity in a Chinese population. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26802595 |full-text-url=https://sci-hub.do/10.1016/j.mcp.2016.01.005 }} * {{medline-title |title=[[SIRT6]], oxidative stress, and aging. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26780861 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746614 }} * {{medline-title |title=Sirt6 regulates dendritic cell differentiation, maturation, and function. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26761436 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761712 }} * {{medline-title |title=The complex role of [[SIRT6]] in carcinogenesis. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26717993 |full-text-url=https://sci-hub.do/10.1093/carcin/bgv167 }} * {{medline-title |title=The expression levels of the sirtuins in patients with BCC. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26631040 |full-text-url=https://sci-hub.do/10.1007/s13277-015-4522-8 }} * {{medline-title |title=Localization of sirtuins ([[SIRT1]]-7) in the aged mouse inner ear. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26472659 |full-text-url=https://sci-hub.do/10.3109/00016489.2015.1093172 }} * {{medline-title |title=Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26471901 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792692 }} * {{medline-title |title=Are sirtuins markers of ovarian aging? |date=10.01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26403315 |full-text-url=https://sci-hub.do/10.1016/j.gene.2015.09.043 }} * {{medline-title |title=Sirtuin-dependent clock control: new advances in metabolism, aging and cancer. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26335311 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610809 }} * {{medline-title |title=[[SIRT6]]/NF-κB signaling axis in ginsenoside Rg1-delayed hematopoietic stem/progenitor cell senescence. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26191269 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503140 }} * {{medline-title |title=Differential expression of sirtuins in the aging rat brain. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26005404 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424846 }} * {{medline-title |title=Scopoletin has a potential activity for anti-aging via autophagy in human lung fibroblasts. |date=15.03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25837273 |full-text-url=https://sci-hub.do/10.1016/j.phymed.2015.01.004 }} * {{medline-title |title=Depletion of [[SI]]RT6 causes cellular senescence, DNA damage, and telomere dysfunction in human chondrocytes. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25819580 |full-text-url=https://sci-hub.do/10.1016/j.joca.2015.03.024 }} * {{medline-title |title=Sirtuin 6 promotes transforming growth factor-β1/H2O2/HOCl-mediated enhancement of hepatocellular carcinoma cell tumorigenicity by suppressing cellular senescence. |date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25683165 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452156 }} * {{medline-title |title=[[SIRT6]] represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age. |date=23.09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25247314 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185372 }} * {{medline-title |title=Changes in human sirtuin 6 gene promoter methylation during aging. |date=07.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24944811 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051482 }} * {{medline-title |title=Sirtuins: guardians of mammalian healthspan. |date=07.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24877878 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077918 }} * {{medline-title |title=Comparative interactomes of [[SIRT6]] and [[SIRT7]]: Implication of functional links to aging. |date=07.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24782448 |full-text-url=https://sci-hub.do/10.1002/pmic.201400001 }} * {{medline-title |title=Chromatin and beyond: the multitasking roles for [[SIRT6]]. |date=02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24438746 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912268 }} * {{medline-title |title=Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and aging. |date=17.01.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24436432 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228987 }}
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