Редактирование: CYP21A2 (раздел)

==Publications==

{{medline-entry
|title=Transient hyper-17-OHPnemia unrelated to cross-reactions with residual fetal adrenal cortex products.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/14988602
|abstract=To clarify the pathogenesis of transient hyper-17alpha-hydroxyprogesteronemia, we initiated a laboratory investigation in a pre-term infant with persistently high serum 17alpha-hydroxyprogesterone (17-OHP) until 2 months of age. Serum 17-OHP level was measured by high-performance liquid chromatography and radioimmunoassay, and gene analysis of [[CYP21A2]] (21-hydroxylase) was performed. Serum 17-OHP level on the 29th day of life was 25.4 ng/ml, and the urinary steroid profile showed low pregnanetriolone. Gene analysis of 21-hydroxylase disclosed no mutation, and 17-OHP normalized by 3 months of age without specific treatment. Transient elevations in 17-OHP, which do not appear related to cross-reactions with products of a residual fetal adrenal cortex, may occur in the first few months of life.
|mesh-terms=* 17-alpha-Hydroxyprogesterone
* Adrenal Cortex
* Adrenocorticotropic Hormone
* Aging
* Chromatography, High Pressure Liquid
* Cross Reactions
* Fetus
* Humans
* Infant, Newborn
* Male
* Polymerase Chain Reaction
* Pregnanetriol
* Radioimmunoassay
* Steroid 21-Hydroxylase
* Time Factors

|full-text-url=https://sci-hub.do/10.1159/000076961
}}