Редактирование: NVL

Nuclear valosin-containing protein-like (NVLp) (Nuclear VCP-like protein) [NVL2]

==Publications==

{{medline-entry
|title=[The effectiveness of non-invasive lung ventilation in lateral amyotrophic sclerosis].
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25345635
|abstract=Lateral amyotrophic sclerosis (LAS) is a very severe neurodegenerative disease with progressive course and terminal respiratory insufficiency. Non-invasive lung ventilation (NLV) is a main method of treatment. We studied the effectiveness of NLV in LAS and assessed patient's adaptation to NLV, life expectancy, compliance and an effect of NLV on spirometric parameters. [[NVL]] was administered to 28 patients, mean age 56.2 ± 9.4 years, including 10 patients with bulbar onset and 16 with spinal onset. The rapid progression of the disease was observed in 15 patients, slow progression in 13 patients. NLV used in regime S extended the life of patients, in particular, patients with spinal onset. The adjustment to the NLV device plays a crucial role. Two types of the adjustment were established: gradual (13 patients) and accelerated (4 patients). The causes of the latter were not found. It should be emphasized that several questions related to the details of [[NVL]] regime should be specified in further research in the field.
|mesh-terms=* Adult
* Aged
* Aged, 80 and over
* Amyotrophic Lateral Sclerosis
* Female
* Humans
* Longevity
* Male
* Middle Aged
* Noninvasive Ventilation
* Pulmonary Ventilation
* Treatment Outcome


}}