Редактирование: HSPB1

Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) [HSP27] [HSP28]

==Publications==

{{medline-entry
|title=The beneficial effects of 15 units of high-intensity circuit training in women is modified by age, baseline insulin resistance and physical capacity.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31102684
|abstract=To investigate the effect of a single and 15 units of high-intensity circuit training (HICT) programme on glucose metabolism, myokines' response and selected genes' expression in women. Thirty-three, non-active women (mean age: 38 ± 12) were split into a HICT (n = 20) or a control group (CON, n = 13). The training protocol included three circuits of nine exercises with own body weight as a workload performed 3 times a week for five weeks. The CON group performed HICT twice. Blood samples were taken before, 1 h and 24 h after the first and last unit to determine IGF-1, myostatin, irisin, decorin, HSP27, interleukin-15 concentrations using the ELISA immunoenzymatic method. To evaluate [[HSPB1]], [[TNF]]-α and [[DCN]] mRNA, real-time PCR was used. Pre- and post-intervention, the oral glucose test and body composition assessment were completed. The following parameters tended to decrease after the 5-week HICT program: insulin and HOMA-IR Training diminished insulin/IGF-1 ratio (51% CI: -63% to -34%) and induced the drop of myostatin concentration but significantly only among middle-aged women and at baseline insulin resistance. Obtained data revealed that HICT improved an insulin sensitivity and diminished myostatin concentration among older, insulin-resistant women with lower baseline physical capacity.
|mesh-terms=* Adult
* Age Factors
* Aging
* Blood Glucose
* Body Composition
* Circuit-Based Exercise
* Decorin
* Energy Metabolism
* Exercise
* Exercise Therapy
* Exercise Tolerance
* Female
* Gene Expression Regulation
* Heat-Shock Proteins
* Humans
* Insulin
* Insulin Resistance
* Insulin-Like Growth Factor I
* Middle Aged
* Myostatin
* Physical Fitness
* Resistance Training
* Young Adult
|keywords=* Decorin
* Heat shock protein
* Insulin growth factors
* Insulin resistance
* Oral glucose tolerance test
|full-text-url=https://sci-hub.do/10.1016/j.diabres.2019.05.009
}}
{{medline-entry
|title=Chicken heat shock protein [[HSPB1]] increases and interacts with αB-crystallin in aged skeletal muscle.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26139560
|abstract=International trading markets of meat require the animal's age information to prevent cross-contamination of ineligible meat products. Individual livestock age is either evaluated from physiological features or verified by breeding history. However, it remains impossible to perform age verification on meat when a suspicion of error occurred in the importing country. To investigate an age-related protein in skeletal muscle of livestock, we compared protein expression among chicken pectoralis major of different ages. Results indicated that the level of expression of chicken [[HSPB1]], one of the small heat shock proteins, was increased in aged muscles. On the other hand, other heat shock proteins, heat shock factors, and myosin heavy chain isoform did not change the expression levels in aged chicken muscle. In addition, we identified that αB-crystallin interacted with [[HSPB1]] in aged chicken muscle. These results suggest that [[HSPB1]] protein forms complexes with αB-crystallin in aged chicken muscle and suppose to become the candidate of age-related bio-marker for verifying the age of chicken meat. 
|mesh-terms=* Aging
* Animals
* Biomarkers
* Chickens
* HSP27 Heat-Shock Proteins
* Humans
* Meat Products
* Muscle, Skeletal
* alpha-Crystallin B Chain
|keywords=* Small heat shock protein
* age-related protein
* poultry
* skeletal muscle
* slaughter age
|full-text-url=https://sci-hub.do/10.1080/09168451.2015.1061419
}}