Редактирование: FMC1

FMC1 homolog (ATP synthase assembly factor FMC1, mitochondrial) (Formation of mitochondrial complex V assembly factor 1 homolog) [C7orf55] [HSPC268]

==Publications==

{{medline-entry
|title=Monoclonal antibody-defined B cell subsets in aging humans and Down's syndrome.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/6240431
|abstract=Peripheral blood from aging and young humans and patients with Down's syndrome, and from age- and sex-matched controls, was studied for the proportions of surface immunoglobulin (SIg ) bearing and monoclonal antibodies [[FMC1]], and FMC7 defined B lymphocytes and B lymphocyte subsets using fluorescent-activated cell sorter. In aging humans, the proportion of SIg  and [[FMC1]]  (that detect all B lymphocytes) were comparable to simultaneously studied healthy young controls. However, FMC7  (that detects a subset of B cells) B cells were significantly (p less than 0.05) increased when compared to young subjects. In aging subjects, the proportions of FMC7  B cells were comparable to their [[FMC1]]  B cells, whereas in young subjects FMC7  B cells were a subset of [[FMC1]]  B cells. In Down's syndrome, a phenomenon similar to aging humans was observed, that is the proportions of FMC7  were increased when compared to age- and sex-matched controls and were comparable to their own [[FMC1]]  B cells. This study demonstrates the abnormality of B lymphocytes in human aging and Down's syndrome. The significance of these findings is discussed.
|mesh-terms=* Adult
* Aged
* Aging
* Antibodies, Monoclonal
* B-Lymphocytes
* Child
* Child, Preschool
* Down Syndrome
* Female
* Humans
* Male
* Receptors, Antigen, B-Cell
* Reference Values

|full-text-url=https://sci-hub.do/10.1159/000212661
}}