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Aging genes 5-9
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__NOTOC__ * [[Aging genes 300|Genes with 300 and more publications]] * [[Aging genes 200-299|Genes with 200-299 publications]] * [[Aging genes 100-199|Genes with 100-199 publications]] * [[Aging genes 90-99|Genes with 90-99 publications]] * [[Aging genes 80-89|Genes with 80-89 publications]] * [[Aging genes 70-79|Genes with 70-79 publications]] * [[Aging genes 60-69|Genes with 60-69 publications]] * [[Aging genes 50-59|Genes with 50-59 publications]] * [[Aging genes 40-49|Genes with 40-49 publications]] * [[Aging genes 30-39|Genes with 30-39 publications]] * [[Aging genes 20-29|Genes with 20-29 publications]] * [[Aging genes 10-19|Genes with 10-19 publications]] * [[Aging genes 5-9|Genes with 5-9 publications]] * [[Aging genes 3-4|Genes with 3-4 publications]] * [[Aging genes 1-2|Genes with 1-2 publications]] * [[Aging_genes_A-Z_table]] ==ARNT== * {{medline-title |title=Loss of [[ARNT]] in skeletal muscle limits muscle regeneration in aging. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33064329 |full-text-url=https://sci-hub.do/10.1096/fj.202000761RR }} * {{medline-title |title=[Arylhydrocarbon receptor nuclear translocator ([[ARNT]]) in human skin during aging.] |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32593246 }} * {{medline-title |title=The E3 ubiquitin ligase [[STUB1]] attenuates cell senescence by promoting the ubiquitination and degradation of the core circadian regulator BMAL1. |date=03.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32041778 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135990 }} * {{medline-title |title=Deficiency of Bmal1 disrupts the diurnal rhythm of haemostasis. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30610898 |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.12.017 }} * {{medline-title |title=Insulin-like growth factor-1 acts as a zeitgeber on hypothalamic circadian clock gene expression via glycogen synthase kinase-3β signaling. |date=02.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217816 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222112 }} * {{medline-title |title=Aging and chromatoid body assembly: Are these two physiological events linked? |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29958504 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108056 }} * {{medline-title |title=Deficiency of circadian clock protein BMAL1 in mice results in a low bone mass phenotype. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26789548 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755907 }} * {{medline-title |title=Circadian clocks govern calorie restriction-mediated life span extension through BMAL1- and IGF-1-dependent mechanisms. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26700733 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799504 }} * {{medline-title |title=Whole blood thrombin generation in Bmal1-deficient mice. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24740693 |full-text-url=https://sci-hub.do/10.1160/TH13-11-0910 }} ==BMP2== * {{medline-title |title=[[GREM1]] inhibits osteogenic differentiation, senescence and BMP transcription of adipose-derived stem cells. |date=09.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32151168 |full-text-url=https://sci-hub.do/10.1080/03008207.2020.1736054 }} * {{medline-title |title=Interleukin-1β-Induced Senescence Promotes Osteoblastic Transition of Vascular Smooth Muscle Cells. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32126555 |full-text-url=https://sci-hub.do/10.1159/000504298 }} * {{medline-title |title=Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging. |date=03.12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352426 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264619 }} * {{medline-title |title=Synthesis of Extracellular Pyrophosphate Increases in Vascular Smooth Muscle Cells During Phosphate-Induced Calcification. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30002059 |full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.311444 }} * {{medline-title |title=Age-Related Insulin-Like Growth Factor Binding Protein-4 Overexpression Inhibits Osteogenic Differentiation of Rat Mesenchymal Stem Cells. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28595186 |full-text-url=https://sci-hub.do/10.1159/000477873 }} * {{medline-title |title=p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner. |date=06.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28382965 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382695 }} * {{medline-title |title=Vaccination with [[DKK1]]-derived peptides promotes bone formation and bone mass in an aged mouse osteoporosis model. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24907907 |full-text-url=https://sci-hub.do/10.1007/s00223-014-9875-2 }} * {{medline-title |title=Enhanced tissue regeneration potential of juvenile articular cartilage. |date=11.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24043472 |full-text-url=https://sci-hub.do/10.1177/0363546513502945 }} * {{medline-title |title=Age-related CXC chemokine receptor-4-deficiency impairs osteogenic differentiation potency of mouse bone marrow mesenchymal stromal stem cells. |date=08.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23742988 |full-text-url=https://sci-hub.do/10.1016/j.biocel.2013.05.034 }} ==BNIP3== * {{medline-title |title=Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training. |date=01.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31306740 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707857 }} * {{medline-title |title=Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training. |date=01.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30030137 |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.07.011 }} * {{medline-title |title=Effects of β-hydroxy-β-methylbutyrate on skeletal muscle mitochondrial content and dynamics, and lipids after 10 days of bed rest in older adults. |date=01.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28705993 |full-text-url=https://sci-hub.do/10.1152/japplphysiol.00192.2017 }} * {{medline-title |title=Akt2 ablation prolongs life span and improves myocardial contractile function with adaptive cardiac remodeling: role of Sirt1-mediated autophagy regulation. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28681509 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595687 }} * {{medline-title |title=In Brief: Mitophagy: mechanisms and role in human disease. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27453450 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071152 }} * {{medline-title |title=Mfn2 deficiency links age-related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway. |date=01.08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27334614 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969577 }} * {{medline-title |title=Interfacing mitochondrial biogenesis and elimination to enhance host pathogen defense and longevity. |date=07-09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26430570 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588546 }} * {{medline-title |title=Coupling mitogenesis and mitophagy for longevity. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26083448 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590656 }} * {{medline-title |title=Dying myofibers in elderly mouse skeletal muscles are characterized by the appearance of dystrophin-encircled vacuoles. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25758773 |full-text-url=https://sci-hub.do/10.1007/s10522-015-9565-0 }} ==BPIFB4== * {{medline-title |title=New Insights for [[BPIFB4]] in Cardiovascular Therapy. |date=28.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32998388 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583974 }} * {{medline-title |title=High TARC plasma levels confer protection to long living individuals by inducing M2 profile. |date=01.2021 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33002742 |full-text-url=https://sci-hub.do/10.1016/j.cyto.2020.155305 }} * {{medline-title |title=Circulating [[BPI]]FB4 Levels Associate With and Influence the Abundance of Reparative Monocytes and Macrophages in Long Living Individuals. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32547549 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272600 }} * {{medline-title |title=Transfer of a human gene variant associated with exceptional longevity improves cardiac function in obese type 2 diabetic mice through induction of the SDF-1/[[CXCR4]] signalling pathway. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32384208 |full-text-url=https://sci-hub.do/10.1002/ejhf.1840 }} * {{medline-title |title=LAV-[[BPIFB4]] associates with reduced frailty in humans and its transfer prevents frailty progression in old mice. |date=28.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31461407 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738439 }} * {{medline-title |title=Longevity-Associated Variant of [[BPIFB4]] Mitigates Monocyte-Mediated Acquired Immune Response. |date=13.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074771 |full-text-url=https://sci-hub.do/10.1093/gerona/glz036 }} * {{medline-title |title=A Model of Evolutionary Selection: The Cardiovascular Protective Function of the Longevity Associated Variant of [[BPIFB4]]. |date=19.10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30347645 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214030 }} * {{medline-title |title=The expression of the [[BPI]]FB4 and [[CXCR4]] associates with sustained health in long-living individuals from Cilento-Italy. |date=22.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28121621 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361669 }} * {{medline-title |title=Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis. |date=31.07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26034043 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496930 }} ==CCN1== * {{medline-title |title=Sodium tanshinone IIA sulfonate restrains fibrogenesis through induction of senescence in mice with induced deep endometriosis. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32651107 |full-text-url=https://sci-hub.do/10.1016/j.rbmo.2020.04.006 }} * {{medline-title |title=Inhibition of cellular communication network factor 1 ([[CCN1]])-driven senescence slows down cartilage inflammaging and osteoarthritis. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32622876 |full-text-url=https://sci-hub.do/10.1016/j.bone.2020.115522 }} * {{medline-title |title=[Aging of skin fibroblasts: genetic and epigenetic factors.] |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32160428 }} * {{medline-title |title=The senescence-associated matricellular protein [[CCN1]] in plasma of human subjects with idiopathic pulmonary fibrosis. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31765873 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023981 }} * {{medline-title |title=[[CCN1]] (CYR61) and [[CCN3]] (NOV) signaling drives human trophoblast cells into senescence and stimulates migration properties. |date=03.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26744771 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853050 }} * {{medline-title |title=Aging increases [[CCN1]] expression leading to muscle senescence. |date=01.01.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24196529 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919975 }} * {{medline-title |title=Impaired intervertebral disc development and premature disc degeneration in mice with notochord-specific deletion of [[CCN2]]. |date=10.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23839921 |full-text-url=https://sci-hub.do/10.1002/art.38075 }} * {{medline-title |title=The matricellular protein [[CCN1]] suppresses lung cancer cell growth by inducing senescence via the p53/p21 pathway. |date=09.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23553737 |full-text-url=https://sci-hub.do/10.1002/jcb.24557 }} * {{medline-title |title=Cysteine-rich protein 61 ([[CCN1]]) domain-specific stimulation of matrix metalloproteinase-1 expression through αVβ3 integrin in human skin fibroblasts. |date=26.04.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23504324 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636922 }} ==CCR5== * {{medline-title |title=The Puzzling Role of Neuron-Specific PMCA Isoforms in the Aging Process. |date=16.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31888192 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941135 }} * {{medline-title |title=[Enhancement can do harm]. |date=08-09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31532388 |full-text-url=https://sci-hub.do/10.1051/medsci/2019136 }} * {{medline-title |title=[[CCR5]]-∆32 is deleterious in the homozygous state in humans. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160814 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613792 }} * {{medline-title |title=[[CCR5]] chemokine receptor gene polymorphisms in ocular toxoplasmosis. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29221851 |full-text-url=https://sci-hub.do/10.1016/j.actatropica.2017.12.012 }} * {{medline-title |title=Peripheral loss of CD8( ) CD161( ) TCRVα7·2( ) mucosal-associated invariant T cells in chronic hepatitis C virus-infected patients. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26681320 |full-text-url=https://sci-hub.do/10.1111/eci.12581 }} * {{medline-title |title=Increased susceptibility of [[CD4]] T cells from elderly individuals to HIV-1 infection and apoptosis is associated with reduced [[CD4]] and enhanced [[CXCR4]] and [[FAS]] surface expression levels. |date=09.10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26452480 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600300 }} * {{medline-title |title=Aging-associated subpopulations of human CD8 T-lymphocytes identified by their [[CD28]] and CD57 phenotypes. |date=11-12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26277688 |full-text-url=https://sci-hub.do/10.1016/j.archger.2015.08.007 }} * {{medline-title |title=Cutting edge: Central memory CD8 T cells in aged mice are virtual memory cells. |date=15.12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24227783 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858473 }} * {{medline-title |title=[[[CCR5]], [[CCR2]], apoe, p53, [[ITGB3]] and [[HFE]] gene polymorphism in Western Siberia long-livers]. |date=2012 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23289212 }} ==CDA== * {{medline-title |title=Cumulative Dis/Advantage and Health Pattern in Late Life: A Comparison between Genders and Welfare State Regimes. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31771483 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367435 }} * {{medline-title |title=Does numerical similarity alter age-related distractibility in working memory? |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31483830 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726243 }} * {{medline-title |title=Can working memory capacity be expanded by boosting working memory updating efficiency in older adults? |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30475011 |full-text-url=https://sci-hub.do/10.1037/pag0000311 }} * {{medline-title |title=Negative Affect Influences Electrophysiological Markers of Visual Working Memory in Mildly Stressed Older Adults. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29872391 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972212 }} * {{medline-title |title=EEG correlates of visual short-term memory in older age vary with adult lifespan cognitive development. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175710 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.10.018 }} * {{medline-title |title=Mini dental assessment: a simple screening test for non-dental staff. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27401181 |full-text-url=https://sci-hub.do/10.1007/s00784-016-1906-0 }} * {{medline-title |title=Electrophysiological Correlates of Subitizing in Healthy Aging. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26098959 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476746 }} * {{medline-title |title=Understanding age-related reductions in visual working memory capacity: examining the stages of change detection. |date=10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24420648 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098047 }} * {{medline-title |title=Retrospective attention enhances visual working memory in the young but not the old: an ERP study. |date=05.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23445536 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618566 }} ==CTCF== * {{medline-title |title=New targeted approaches for epigenetic age predictions. |date=24.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32580727 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315536 }} * {{medline-title |title=Blood DNA Methylation and Aging: A Cross-Sectional Analysis and Longitudinal Validation in the InCHIANTI Study. |date=15.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32147700 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566335 }} * {{medline-title |title=In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31520345 |full-text-url=https://sci-hub.do/10.1007/s10522-019-09834-1 }} * {{medline-title |title=Genetic Insights Into Frailty: Association of 9p21-23 Locus With Frailty. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29765957 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938407 }} * {{medline-title |title=[[HMGB2]] Loss upon Senescence Entry Disrupts Genomic Organization and Induces [[CTCF]] Clustering across Cell Types. |date=17.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29706538 |full-text-url=https://sci-hub.do/10.1016/j.molcel.2018.03.030 }} * {{medline-title |title=Polycomb repressive complex 2 epigenomic signature defines age-associated hypermethylation and gene expression changes. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25880792 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623031 }} * {{medline-title |title=Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24034465 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053985 }} * {{medline-title |title=Chromatin remodeling of human subtelomeres and TERRA promoters upon cellular senescence: commonalities and differences between chromosomes. |date=05.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23644601 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741221 }} * {{medline-title |title=Long-lasting alterations to DNA methylation and ncRNAs could underlie the effects of fetal alcohol exposure in mice. |date=07.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23580197 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701217 }} ==CXCL2== * {{medline-title |title=Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33041998 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525127 }} * {{medline-title |title=Inflammatory and Senescent Phenotype of Pancreatic Stellate Cells Induced by Sqstm1 Downregulation Facilitates Pancreatic Cancer Progression. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182922 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535784 }} * {{medline-title |title=Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice. |date=02.05.2019 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regulates senescence in an Rb-dependent manner in cancer cell lines. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26176204 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825635 }} * {{medline-title |title=A dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24400780 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032615 }} * {{medline-title |title=Integrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24314125 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059541 }} * {{medline-title |title=PPARβ/δ promotes [[HRAS]]-induced senescence and tumor suppression by potentiating p-ERK and repressing p-AKT signaling. |date=13.11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24213576 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Promote the Clearance of Aβ<sub>1-42</sub> in SAMP8 Mice: Mechanism Research of a Traditional Chinese Formula Against Alzheimer's Disease. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32496993 |full-text-url=https://sci-hub.do/10.2174/1871527319666200604174223 }} * {{medline-title |title=Dysregulations of mitochondrial quality control and autophagic flux at an early age lead to progression of sarcopenia in SAMP8 mice. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32130580 |full-text-url=https://sci-hub.do/10.1007/s10522-020-09867-x }} * {{medline-title |title=Deacetylation of [[LAMP1]] drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31544977 |full-text-url=https://sci-hub.do/10.1002/jcp.29182 }} * {{medline-title |title=A pH probe inhibits senescence in mesenchymal stem cells. |date=07.12.2018 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|title=Association between a Deficit Accumulation Frailty Index and Mobility Outcomes in Older Adults: Secondary Analysis of the Lifestyle Interventions and Independence for Elders (LIFE) Study. |date=22.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33266358 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700674 }} * {{medline-title |title=Impact of Anticholinergic Medication Burden on Mobility and Falls in the Lifestyle Interventions for Elders (LIFE) Study. |date=16.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32947839 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564216 }} * {{medline-title |title=Impact and Lessons From the Lifestyle Interventions and Independence for Elders (LIFE) Clinical Trials of Physical Activity to Prevent Mobility Disability. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32105353 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187344 }} * {{medline-title |title=Lactobacillus rescues postnatal 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|date=13.02.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23408054 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130338 }} ==MSTN== * {{medline-title |title=Age- and stage-dependent variations of muscle-specific gene expression in brown trout Salmo trutta L. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28408166 |full-text-url=https://sci-hub.do/10.1016/j.cbpb.2017.04.001 }} * {{medline-title |title=Activity of metabolic enzymes and muscle-specific gene expression in parr and smolts Atlantic salmon Salmo salar L. of different age groups. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28315163 |full-text-url=https://sci-hub.do/10.1007/s10695-017-0357-0 }} * {{medline-title |title=miR-30e is negatively regulated by myostatin in skeletal muscle and is functionally related to fiber-type composition. |date=01.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28338991 |full-text-url=https://sci-hub.do/10.1093/abbs/gmx019 }} * {{medline-title |title=Muscle-Related Polymorphisms ([[MSTN]] rs1805086 and [[ACTN3]] rs1815739) Are Not Associated with Exceptional Longevity in Japanese Centenarians. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27861536 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115755 }} * {{medline-title |title=Temporal and spatial expression of Smads and their correlation with [[YAP1]] expression in sheep. |date=26.08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27706608 |full-text-url=https://sci-hub.do/10.4238/gmr.15037715 }} * {{medline-title |title=Quantification of [[GDF11]] and Myostatin in Human Aging and Cardiovascular Disease. |date=14.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27304512 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913514 }} * {{medline-title |title=Morphological analysis and muscle-associated gene expression during different muscle growth phases of Megalobrama amblycephala. |date=28.09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26436405 |full-text-url=https://sci-hub.do/10.4238/2015.September.28.16 }} * {{medline-title |title=The effect of exercise mode on the acute response of satellite cells in old men. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26367861 |full-text-url=https://sci-hub.do/10.1111/apha.12601 }} * {{medline-title |title=Association of the K153R polymorphism in the myostatin gene and extreme longevity. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23354683 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825013 }} ==PNN== * {{medline-title |title=Hyaluronan degradation and release of a hyaluronan-aggrecan complex from perineuronal nets in the aged mouse brain. |date=28.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33253804 |full-text-url=https://sci-hub.do/10.1016/j.bbagen.2020.129804 }} * {{medline-title |title=Maturation of [[PNN]] and ErbB4 Signaling in Area [[CA2]] during Adolescence Underlies the 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|full-text-url=https://sci-hub.do/10.1016/j.neuint.2017.11.001 }} * {{medline-title |title=Brain ageing changes proteoglycan sulfation, rendering perineuronal nets more inhibitory. |date=28.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28657900 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509459 }} * {{medline-title |title=Removal of Perineuronal Nets Unlocks Juvenile Plasticity Through Network Mechanisms of Decreased Inhibition and Increased Gamma Activity. |date=01.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28039374 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596863 }} * {{medline-title |title=Age-Related Deterioration of Perineuronal Nets in the Primary Auditory Cortex of Mice. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27877127 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099154 }} * {{medline-title |title=Spatio-temporal differences in perineuronal net expression in the mouse hippocampus, with reference to 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to the other human RecQ helicase proteins. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26717024 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903426 }} ==SMAD2== * {{medline-title |title=Effects of Tenascin C on the Integrity of Extracellular Matrix and Skin Aging. |date=18.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33217999 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698786 }} * {{medline-title |title=The effects and mechanism of collagen peptide and elastin peptide on skin aging induced by D-galactose combined with ultraviolet radiation. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32717457 |full-text-url=https://sci-hub.do/10.1016/j.jphotobiol.2020.111964 }} * {{medline-title |title=Prostate epithelial-specific expression of activated PI3K drives stromal collagen production and accumulation. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31674011 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histone deacetylase functions as a potential oncogene in human melanoma. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 }} * {{medline-title |title=[[SQSTM1]]/p62 mediates crosstalk between autophagy and the UPS in DNA repair. |date=02.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27391408 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391493 }} * {{medline-title |title=Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis. |date=02.11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26391655 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824610 }} ==VHL== * {{medline-title |title=Hypoxic response regulators RHY-1 and EGL-9/PHD promote longevity through a [[VHL]]-1-independent transcriptional response. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32399915 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|title=BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence. |date=15.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27794120 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135304 }} * {{medline-title |title=Increased bone morphogenetic protein signaling contributes to age-related declines in neurogenesis and cognition. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26827654 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735642 }} * {{medline-title |title=Control of the Normal and Pathological Development of Neural Stem and Progenitor Cells by the PC3/Tis21/Btg2 and Btg1 Genes. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25967096 |full-text-url=https://sci-hub.do/10.1002/jcp.25038 }} * {{medline-title |title=FSH-FSHR3-stem cells in ovary surface epithelium: basis for adult ovarian biology, failure, aging, and cancer. |date=01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25269615 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{{medline-title |title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827 }} * {{medline-title |title=Rare variants in [[CFI]], [[C3]] and [[C9]] are associated with high risk of advanced age-related macular degeneration. |date=11.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24036952 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902040 }} ==CCL4== * {{medline-title |title=Microglial translational profiling reveals a convergent [[APOE]] pathway from aging, amyloid, and tau. |date=03.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30082275 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122978 }} * {{medline-title |title=Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound 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enhances vulnerability to THC reward in adolescent female mice. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32095523 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015690 }} * {{medline-title |title=Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30911178 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548519 }} * {{medline-title |title=Stimulation of brain glucose uptake by cannabinoid CB2 receptors and its therapeutic potential in Alzheimer's disease. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26976670 |full-text-url=https://sci-hub.do/10.1016/j.neuropharm.2016.03.015 }} * {{medline-title |title=Sustained Endocannabinoid Signaling Compromises Decidual Function and Promotes Inflammation-induced Preterm Birth. |date=08.04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26900150 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|title=Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31310445 |full-text-url=https://sci-hub.do/10.1111/pcmr.12811 }} * {{medline-title |title=H O promotes the aging process of melanogenesis through modulation of [[MITF]] and Nrf2. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805890 |full-text-url=https://sci-hub.do/10.1007/s11033-019-04708-8 }} * {{medline-title |title=Deregulated [[MITF]] sumoylation: A route to melanoma. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28868345 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540212 }} * {{medline-title |title=Phosphorylation of [[MITF]] by AKT affects its downstream targets and causes [[TP53]]-dependent cell senescence. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27702651 |full-text-url=https://sci-hub.do/10.1016/j.biocel.2016.09.029 }} * {{medline-title |title=Parthenolide induces [[MITF]]-M downregulation and senescence in patient-derived [[MITF]]-M(high) melanoma cell populations. |date=23.02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26824319 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891023 }} * {{medline-title |title=Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanoma. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25030625 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198745 }} ==NNT== * {{medline-title |title=Yoga, Health-Related Quality of Life and Mental Well-Being: A Re-analysis of a Meta-analysis Using the Quality Effects Model. |date=16.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31814012 |full-text-url=https://sci-hub.do/10.1093/gerona/glz284 }} * {{medline-title |title=Statins After Myocardial Infarction in the Oldest: A Cohort Study in the Clinical Practice Research Datalink Database. 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from Pancreatic Resection for Adenocarcinoma in the Elderly. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27826771 |full-text-url=https://sci-hub.do/10.1007/s00268-016-3793-6 }} * {{medline-title |title=Restoration of Mitochondrial NAD Levels Delays Stem Cell Senescence and Facilitates Reprogramming of Aged Somatic Cells. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27428041 |full-text-url=https://sci-hub.do/10.1002/stem.2460 }} * {{medline-title |title=Relative importance of redox buffers GSH and NAD(P)H in age-related neurodegeneration and Alzheimer disease-like mouse neurons. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24655393 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116450 }} ==NOS2== * {{medline-title |title=Metformin alters peripheral blood mononuclear cells (PBMC) senescence biomarkers gene expression in type 2 diabetic patients. |date=01.2021 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33187870 |full-text-url=https://sci-hub.do/10.1016/j.jdiacomp.2020.107758 }} * {{medline-title |title=Genetic background, epigenetic factors and dietary interventions which influence human longevity. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31309340 |full-text-url=https://sci-hub.do/10.1007/s10522-019-09824-3 }} * {{medline-title |title=Secreted α-Klotho maintains cartilage tissue homeostasis by repressing [i][[NOS2]][/i] and [i]ZIP8-MMP13[/i] catabolic axis. |date=19.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29920476 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046234 }} * {{medline-title |title=Analysis of molecular networks and targets mining of Chinese herbal medicines on anti-aging. |date=28.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28031022 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198498 }} * {{medline-title |title=All-trans retinoic acid (ATRA) prevents lipopolysaccharide-induced neuroinflammation, amyloidogenesis 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neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging. |date=28.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30923322 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438979 }} * {{medline-title |title=Mild Behavioral Impairment as a Marker of Cognitive Decline in Cognitively Normal Older Adults. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30902566 |full-text-url=https://sci-hub.do/10.1016/j.jagp.2019.01.215 }} * {{medline-title |title=The course of neuropsychiatric symptoms in patients with dementia in primary care. |date=31.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30517631 |full-text-url=https://sci-hub.do/10.1093/fampra/cmy117 }} * {{medline-title |title=Serum calcium levels and neuropsychological performance in depression and matched healthy controls: Reversal of correlation a marker of the aging cognitive clock? |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29587243 |full-text-url=https://sci-hub.do/10.1016/j.psyneuen.2018.03.012 }} * {{medline-title |title=Persistent use of psychotropic drugs in nursing home residents in Norway. |date=13.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28193181 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307887 }} * {{medline-title |title=FDG-PET and Neuropsychiatric Symptoms among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging. |date=14.07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27447426 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981903 }} * {{medline-title |title=Cardiorenal fibrosis and dysfunction in aging: Imbalance in mediators and regulators of collagen. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26774586 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754975 }} * {{medline-title |title=Personalized technology to support older adults with and without cognitive impairment living at home. |date=02.2015 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* {{medline-title |title=Aging of blood can be tracked by DNA methylation changes at just three CpG sites. |date=03.02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24490752 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053864 }} ==PDK1== * {{medline-title |title=Inhibition of 3-phosphoinositide-dependent protein kinase 1 ([[PDK1]]) can revert cellular senescence in human dermal fibroblasts. |date=08.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33229519 |full-text-url=https://sci-hub.do/10.1073/pnas.1920338117 }} * {{medline-title |title=The Impact of the PI3K/Akt Signaling Pathway in Anxiety and Working Memory in Young and Middle-Aged [[PDK1]] K465E Knock-In Mice. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32457586 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225327 }} * {{medline-title |title=Peripheral Circulating Exosomal miRNAs Potentially Contribute to the Regulation of Molecular Signaling Networks in Aging. |date=11.03.2020 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|full-text-url=https://sci-hub.do/10.1016/j.vetimm.2020.110013 }} * {{medline-title |title=Epidemiology of pituitary pars intermedia dysfunction: A systematic literature review of clinical presentation, disease prevalence and risk factors. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29704935 |full-text-url=https://sci-hub.do/10.1016/j.tvjl.2018.03.002 }} * {{medline-title |title=Effect of Age, Season, Body Condition, and Endocrine Status on Serum Free Cortisol Fraction and Insulin Concentration in Horses. |date=03-04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26860336 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913614 }} * {{medline-title |title=Age-related Qualitative Histological and Quantitative Stereological Changes in the Equine Pituitary. |date=02-04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26810844 |full-text-url=https://sci-hub.do/10.1016/j.jcpa.2015.11.006 }} * {{medline-title |title=What's New in Old Horses? Postmortem Diagnoses in Mature and Aged Equids. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26459516 |full-text-url=https://sci-hub.do/10.1177/0300985815608674 }} * {{medline-title |title=Pituitary pars intermedia dysfunction does not necessarily impair insulin sensitivity in old horses. |date=01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25240230 |full-text-url=https://sci-hub.do/10.1016/j.domaniend.2014.07.003 }} * {{medline-title |title=Evaluation of the effects of age and pituitary pars intermedia dysfunction on corneal sensitivity in horses. |date=07.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23802675 |full-text-url=https://sci-hub.do/10.2460/ajvr.74.7.1030 }} * {{medline-title |title=Comparison of hair follicle histology between horses with pituitary pars intermedia dysfunction and excessive hair growth and normal aged horses. |date=02.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23331700 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|full-text-url=https://sci-hub.do/10.3881/j.issn.1000-503X.2015.03.001 }} * {{medline-title |title=DBA/2J genetic background exacerbates spontaneous lethal seizures but lessens amyloid deposition in a mouse model of Alzheimer's disease. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25933409 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416920 }} * {{medline-title |title=Associations between biomarkers and age in the presenilin 1 E280A autosomal dominant Alzheimer disease kindred: a cross-sectional study. |date=03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25580592 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355261 }} * {{medline-title |title=Age-dependent, non-cell-autonomous deposition of amyloid from synthesis of β-amyloid by cells other than excitatory neurons. |date=05.03.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24599465 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942582 }} * {{medline-title |title=Endogenous expression of FAD-linked PS1 impairs proliferation, neuronal differentiation and survival of adult hippocampal progenitors. |date=20.10.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24138759 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853710 }} ==RAD50== * {{medline-title |title=[[ATM]] Deficiency Accelerates DNA Damage, Telomere Erosion, and Premature T Cell Aging in HIV-Infected Individuals on Antiretroviral Therapy. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31781094 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856652 }} * {{medline-title |title=Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells. |date=01.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29775409 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172637 }} * {{medline-title |title=Phosphorylation of WHIRLY1 by CIPK14 Shifts Its Localization and Dual Functions in Arabidopsis. |date=01.05.2017 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technology adoption among older adult veterans: the interplay of social and cognitive factors. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29019416 |full-text-url=https://sci-hub.do/10.1080/13607863.2017.1381946 }} * {{medline-title |title=Repeatability of Choroidal Thickness Measurements on Enhanced Depth Imaging Optical Coherence Tomography Using Different Posterior Boundaries. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27345731 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687829 }} * {{medline-title |title=HIV cure strategies: how good must they be to improve on current antiretroviral therapy? |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25397616 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232561 }} * {{medline-title |title=Quadriceps intramuscular fat fraction rather than muscle size is associated with knee osteoarthritis. |date=02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24361743 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|title=Reducing [[INS]]-[[IGF1]] signaling protects against non-cell autonomous vesicle rupture caused by [[SNCA]] spreading. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31354022 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144869 }} * {{medline-title |title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes. |date=04.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490 }} * {{medline-title |title=Age-dependent accumulation of oligomeric [[SNCA]]/α-synuclein from impaired degradation in mutant [[LRRK2]] knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA). |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30983487 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984454 }} * 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|title=In silico analysis and molecular dynamics simulation of human superoxide dismutase 3 ([[SOD3]]) genetic variants. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30206983 |full-text-url=https://sci-hub.do/10.1002/jcb.27636 }} * {{medline-title |title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277 |full-text-url=https://sci-hub.do/10.1111/rda.13091 }} * {{medline-title |title=Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28767699 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540417 }} * {{medline-title |title=Extracellular superoxide dismutase deficiency impairs wound healing in advanced age by reducing neovascularization and fibroblast function. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26663425 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IL-10 T Cells Initiate Rapid IL-10 Production To Suppress Anamnestic T Cell Responses during Secondary Malaria Infection. |date=15.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27630165 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055201 }} * {{medline-title |title=Combinatorial approach to cancer immunotherapy: strength in numbers. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27256570 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608090 }} ==TIMP1== * {{medline-title |title=Senescence Reprogramming by [[TIMP1]] Deficiency Promotes Prostate Cancer Metastasis. |date=26.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33186519 |full-text-url=https://sci-hub.do/10.1016/j.ccell.2020.10.012 }} * {{medline-title |title=Design, cyclization, and optimization of [[MMP13]]-[[TIMP1]] interaction-derived self-inhibitory peptides against chondrocyte senescence in osteoarthritis. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352228 |full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2018.10.141 }} * {{medline-title |title=Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30142172 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108478 }} * {{medline-title |title=Timing and duration of nursing from birth affect neonatal porcine uterine matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27866058 |full-text-url=https://sci-hub.do/10.1016/j.domaniend.2016.10.002 }} * {{medline-title |title=Effect of [[TIMP1]] transfection on [[PTEN]] expression in human kidney proximal tubular cells. |date=21.12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26782378 |full-text-url=https://sci-hub.do/10.4238/2015.December.21.6 }} * {{medline-title |title=Biological Effects Induced by Specific Advanced Glycation 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bladder responses to capsaicin and GSK-1016790A in retired-breeder female rats with diminished volume sensitivity. |date=01.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30019934 |full-text-url=https://sci-hub.do/10.1152/ajprenal.00198.2018 }} * {{medline-title |title=Cartilage-Specific Knockout of the Mechanosensory Ion Channel [[TRPV4]] Decreases Age-Related Osteoarthritis. |date=08.07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27388701 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937413 }} * {{medline-title |title=Increasing [[TRPV4]] expression restores flow-induced dilation impaired in mesenteric arteries with aging. |date=07.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26947561 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780030 }} * {{medline-title |title=Berberine via suppression of transient receptor potential vanilloid 4 channel improves vascular stiffness in mice. |date=11.2015 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Alzheimer's disease by targeting [[TSC1]]-mTOR-Tau signaling. |date=25.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501742 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.02.201 }} * {{medline-title |title=Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29023667 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716871 }} * {{medline-title |title=Complex inhibition of autophagy by mitochondrial aldehyde dehydrogenase shortens lifespan and exacerbates cardiac aging. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28347844 |full-text-url=https://sci-hub.do/10.1016/j.bbadis.2017.03.016 }} * {{medline-title |title=Autophagy inhibition switches low-dose camptothecin-induced premature senescence to apoptosis in human colorectal cancer cells. |date=01.08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24858802 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* {{medline-title |title=Effect of age on expression of spermatogonial markers in bovine testis and isolated cells. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27180120 |full-text-url=https://sci-hub.do/10.1016/j.anireprosci.2016.04.004 }} * {{medline-title |title=It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and [[UCHL1]] in Alzheimer Disease. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26881020 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736377 }} * {{medline-title |title=Loss of [[UCHL1]] promotes age-related degenerative changes in the enteric nervous system. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24994982 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063237 }} ==VDAC1== * {{medline-title |title=Low abundance of [[NDUFV2]] and [[NDUFS4]] subunits of the hydrophilic complex I domain and [[VDAC1]] predicts mammalian longevity. |date=07.2020 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defect in DNA damage response and anti-oxidative capacity. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30008586 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036081 }} * {{medline-title |title=[[XRCC1]] and XPD genetic polymorphisms and susceptibility to age-related cataract: a meta-analysis. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25873778 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384174 }} * {{medline-title |title=Polymorphisms of DNA repair genes XPD (Lys751Gln) and [[XRCC1]] (Arg399Gln), and the risk of age-related cataract: a meta-analysis. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25285569 |full-text-url=https://sci-hub.do/10.3109/02713683.2014.957325 }} * {{medline-title |title=Association between DNA repair genes (XPD and [[XRCC1]]) polymorphisms and susceptibility to age-related cataract ([[ARC]]): a meta-analysis. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24906341 |full-text-url=https://sci-hub.do/10.1007/s00417-014-2679-2 }} * {{medline-title |title=Polymorphisms in [[ERCC1]] C8092A predict progression-free survival in metastatic/recurrent nasopharyngeal carcinoma treated with cisplatin-based chemotherapy. |date=08.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23712330 |full-text-url=https://sci-hub.do/10.1007/s00280-013-2196-8 }} ==AGA== * {{medline-title |title=Extract of Plumbago zeylanica enhances the growth of hair follicle dermal papilla cells with down-regulation of 5α-reductase type II. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32125089 |full-text-url=https://sci-hub.do/10.1111/jocd.13355 }} * {{medline-title |title=Relationship between androgenic alopecia and white matter hyperintensities in apparently healthy subjects. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31250269 |full-text-url=https://sci-hub.do/10.1007/s11682-019-00147-y }} * {{medline-title |title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756 }} * {{medline-title |title=The Impact of Being Born Preterm or Small for Gestational Age on Early Vascular Aging in Adolescents. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29960764 |full-text-url=https://sci-hub.do/10.1016/j.jpeds.2018.05.056 }} * {{medline-title |title=Adult height of preterm infants: a longitudinal cohort study. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27998884 |full-text-url=https://sci-hub.do/10.1136/archdischild-2016-310469 }} * {{medline-title |title=The telomere attrition rate is not accelerated in women born small for gestational age: A birth cohort study. |date=05.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27871926 |full-text-url=https://sci-hub.do/10.1016/j.gene.2016.11.030 }} * {{medline-title |title=Does prostaglandin D2 hold the cure to male pattern baldness? |date=04.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24521203 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982925 }} ==ALB== * {{medline-title |title=Effects of Age on Inflammatory Profiles and Nutrition/Energy Metabolism in Domestic Cats. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33262938 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695597 }} * {{medline-title |title=Expression of Transferrin and Albumin in the Sperm-Storage Tubules of Japanese Quail and their Possible Involvement in Long-Term Sperm Storage. |date=25.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32174770 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063080 }} * {{medline-title |title=Blood Chemistry Reference Values for Free-Ranging Asiatic Black Bears ( Ursus thibetanus) by Season, Age, and Sex. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29671714 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Lessons from natural fertility populations. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24676403 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389129 }} ==AMPH== * {{medline-title |title=Effects of amphetamine exposure during adolescence on behavior and prelimbic cortex neuron activity in adulthood. |date=01.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29792867 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026035 }} * {{medline-title |title=The effects of amphetamine exposure on juvenile rats on the neuronal morphology of the limbic system at prepubertal, pubertal and postpubertal ages. |date=11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27208629 |full-text-url=https://sci-hub.do/10.1016/j.jchemneu.2016.05.004 }} * {{medline-title |title=Amphetamine modulates brain signal variability and working memory in younger and older adults. |date=16.06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26034283 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on working memory in rats. |date=01.04.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23291159 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566264 }} ==ATF3== * {{medline-title |title=[[ATF3]] represses [[PINK1]] gene transcription in lung epithelial cells to control mitochondrial homeostasis. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29363258 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847866 }} * {{medline-title |title=p38 MAPK inhibits nonsense-mediated RNA decay in response to persistent DNA damage in noncycling cells. |date=15.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28765281 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602387 }} * {{medline-title |title=Aging Triggers Cytoplasmic Depletion and Nuclear Translocation of the E3 Ligase Mahogunin: A Function for Ubiquitin in Neuronal Survival. |date=04.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28475871 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autophagy, and mitochondrial metabolism in murine skeletal and cardiac muscle during aging. |date=26.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28238968 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361683 }} * {{medline-title |title=Autophagic homeostasis is required for the pluripotency of cancer stem cells. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27929731 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324853 }} * {{medline-title |title=Macroautophagy is impaired in old murine brain tissue as well as in senescent human fibroblasts. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27825071 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099282 }} * {{medline-title |title=Follicle-stimulating hormone promotes age-related endometrial atrophy through cross-talk with transforming growth factor beta signal transduction pathway. |date=04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25393561 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364840 }} ==ATRX== * {{medline-title |title=[[ATRX]]-[[DAXX]] Complex Expression Levels and Telomere Length in Normal Young and Elder Autopsy Human Brains. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31361513 |full-text-url=https://sci-hub.do/10.1089/dna.2019.4752 }} * {{medline-title |title=Inactivation of hepatic [[ATRX]] in [i]Atrx[/i] Foxg1cre mice prevents reversal of aging-like phenotypes by thyroxine. |date=07.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883366 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046231 }} * {{medline-title |title=Mechanistic understanding of the role of [[ATRX]] in senescence provides new insight for combinatorial therapies with [[CDK4]] inhibitors. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29404388 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791849 }} * {{medline-title |title=GBM-associated mutations and altered protein expression are more common in young patients. |date=25.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27579614 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342491 }} * {{medline-title |title=Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26577303 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853592 }} * {{medline-title |title=[[MDM2]] turnover and expression of [[ATRX]] determine the choice between quiescence and senescence in response to [[CDK4]] inhibition. |date=10.04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25803170 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480747 }} * {{medline-title |title=Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span. |date=05.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23563309 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635723 }} ==CBL== * {{medline-title |title=Effects of cerebrolysin on nerve growth factor system in the aging rat brain. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172008 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701766 }} * {{medline-title |title=Skeletal Muscle CAP Expression Increases after Dietary Restriction and Aerobic Training in Women with a History of Gestational Diabetes. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28989819 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628746 }} * {{medline-title |title=Intranasal Cerebrolysin Attenuates Learning and Memory Impairments in D-galactose-Induced Senescence in Mice. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27894939 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.11.011 }} * {{medline-title |title=Neuroprotective effects of Cerebrolysin in triple repeat Tau transgenic model of Pick's disease and fronto-temporal tauopathies. |date=26.11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26611895 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662012 }} * {{medline-title |title=Cerebrolysin Accelerates Metamorphosis and Attenuates Aging-Accelerating Effect of High Temperature in Drosophila Melanogaster. |date=01.10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25798213 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367862 }} * {{medline-title |title=Cerebrolysin™ efficacy in a transgenic model of tauopathy: role in regulation of mitochondrial structure. |date=21.07.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25047000 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122761 }} * {{medline-title |title=Association analyses of insulin signaling pathway gene polymorphisms with healthy aging and longevity in Americans of Japanese ancestry. |date=03.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23770741 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968832 }} ==CCL20== * {{medline-title |title=Assessment of neuroinflammation in the aging hippocampus using large-molecule microdialysis: Sex differences and role of purinergic receptors. |date=07.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33166661 |full-text-url=https://sci-hub.do/10.1016/j.bbi.2020.11.013 }} * {{medline-title |title=p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to non-nucleoside reverse transcriptase inhibitors. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32272174 |full-text-url=https://sci-hub.do/10.1016/j.antiviral.2020.104784 }} * {{medline-title |title=Effects of the Consumption of Milk Biofortified with Selenium, Vitamin E, and Different Fatty Acid Profile on Immune Response in the Elderly. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29193757 |full-text-url=https://sci-hub.do/10.1002/mnfr.201700307 }} * {{medline-title |title=Human Monocyte Subsets Are Transcriptionally and Functionally Altered in Aging in Response to Pattern Recognition Receptor Agonists. |date=15.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28696254 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548610 }} * {{medline-title |title=Interferon-gamma deficiency protects against aging-related goblet cell loss. |date=04.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27623073 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323102 }} * {{medline-title |title=Age dependent changes in the LPS induced transcriptome of bovine dermal fibroblasts occurs without major changes in the methylome. |date=27.01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25623529 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312471 }} * {{medline-title |title=Dendritic cells from aged subjects contribute to chronic airway inflammation by activating bronchial epithelial cells under steady state. |date=11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24759206 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205198 }} ==CPD== * {{medline-title |title=Incidental versus clinically diagnosed differentiated thyroid cancer in both adult and elderly subjects: histological characteristics and follow-up in a retrospective analysis from a single institution. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31970586 |full-text-url=https://sci-hub.do/10.1007/s12020-020-02200-z }} * {{medline-title |title=Reduced proliferation capacity of lung cells in chronic obstructive pulmonary disease. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29470706 |full-text-url=https://sci-hub.do/10.1007/s00391-018-1377-9 }} * {{medline-title |title=What Do Clinical Supervisors Require to Teach Residents in Family Medicine How to Care for Seniors? |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29310735 |full-text-url=https://sci-hub.do/10.1017/S0714980817000460 }} * {{medline-title |title=Survey of Australasian geriatricians' satisfaction with, and preferences for, continuing professional development. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27087018 |full-text-url=https://sci-hub.do/10.1111/imj.13116 }} * {{medline-title |title=The aging psychiatrist: lessons from our colleagues in surgery and anaesthesia. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912470 |full-text-url=https://sci-hub.do/10.1177/1039856216632401 }} * {{medline-title |title=Effects of donor age and proliferative aging on the phenotype stability of rat aortic smooth muscle cells. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26603458 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673651 }} * {{medline-title |title=Specificity of cytochemical and fluorescence methods of senescence-associated β-galactosidase detection for ageing driven by replication and time. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24878779 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090812 }} ==CSF1R== * {{medline-title |title=[[CSF1R]] blockade induces macrophage ablation and results in mouse choroidal vascular atrophy and [[RPE]] disorganization. |date=01.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32234210 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156269 }} * {{medline-title |title=[[CSF1R]] inhibitor PLX5622 and environmental enrichment additively improve metabolic outcomes in middle-aged female mice. |date=02.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32007953 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041757 }} * {{medline-title |title=Modulation of Microglia by Voluntary Exercise or [[CSF1R]] Inhibition Prevents Age-Related Loss of Functional Motor Units. |date=05.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31693894 |full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.10.003 }} * {{medline-title |title=Forced turnover of aged microglia induces an intermediate phenotype but does not rebalance CNS environmental cues driving priming to immune challenge. |date=26.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30477578 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260864 }} * {{medline-title |title=Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30276955 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260908 }} * {{medline-title |title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]]. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905 }} * {{medline-title |title=Pleiotropic effects of extended blockade of [[CSF1]]R signaling in adult mice. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24652541 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378363 }} ==CTSB== * {{medline-title |title=Myocardial cathepsin D is downregulated in sudden cardiac death. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32176724 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075574 }} * {{medline-title |title=A Free Radical-Generating System Regulates Amyloid Oligomers: Involvement of Cathepsin B. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400084 |full-text-url=https://sci-hub.do/10.3233/JAD-170159 }} * {{medline-title |title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 }} * {{medline-title |title=Involvement of lysosomal dysfunction in autophagosome accumulation and early pathologies in adipose tissue of obese mice. |date=03.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28121218 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388215 }} * {{medline-title |title=Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function. |date=09.08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27345423 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029441 }} * {{medline-title |title=The association of serum cathepsin B concentration with age-related cardiovascular-renal subclinical state in a healthy Chinese population. |date=07-08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27032082 |full-text-url=https://sci-hub.do/10.1016/j.archger.2016.03.015 }} * {{medline-title |title=Decreased serum level of [[HMGB1]] and MyD88 during human aging progress in healthy individuals. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26130428 |full-text-url=https://sci-hub.do/10.1007/s40520-015-0402-8 }} ==CYP2E1== * {{medline-title |title=DNA methylation and histone acetylation changes to cytochrome P450 2E1 regulation in normal aging and impact on rates of drug metabolism in the liver. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32221779 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287002 }} * {{medline-title |title=Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of rats. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396457 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681801 }} * {{medline-title |title=2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms. |date=01.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30939745 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479705 }} * {{medline-title |title=Neuroprotective Effect of Dioscin on the 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}} ==DSP== * {{medline-title |title=Noradrenergic dysfunction accelerates LPS-elicited inflammation-related ascending sequential neurodegeneration and deficits in non-motor/motor functions. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247288 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754798 }} * {{medline-title |title=Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29517586 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895171 }} * {{medline-title |title=Metabolic Syndrome Components Are Associated With Symptomatic Polyneuropathy Independent of Glycemic Status. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26965720 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839175 }} * {{medline-title |title=Analysis of diarrhetic shellfish 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|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392 }} * {{medline-title |title=Effects of β-hydroxy-β-methylbutyrate on skeletal muscle mitochondrial content and dynamics, and lipids after 10 days of bed rest in older adults. |date=01.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28705993 |full-text-url=https://sci-hub.do/10.1152/japplphysiol.00192.2017 }} * {{medline-title |title=Mitochondrial activity and dynamics changes regarding metabolism in ageing and obesity. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27993601 |full-text-url=https://sci-hub.do/10.1016/j.mad.2016.12.005 }} * {{medline-title |title=Inhibition of peroxisome fission, but not mitochondrial fission, increases yeast chronological lifespan. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25840089 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614869 }} ==FOXP3== * {{medline-title |title=Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season. |date=21.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31864349 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925900 }} * {{medline-title |title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663 }} * {{medline-title |title=Enhanced expression of PD-1 and other activation markers by CD4 T cells of young but not old patients with metastatic melanoma. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29546435 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951899 }} * {{medline-title |title=Non-linear patterns in age-related DNA methylation may reflect [[CD4]] T cell differentiation. |date=03.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28387568 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501198 }} * {{medline-title |title=Novel Senescent Regulatory T-Cell Subset with Impaired Suppressive Function in Rheumatoid Arthritis. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28373873 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357868 }} * {{medline-title |title=Age-related changes in CD4 CD25 [[FOXP3]] regulatory T cells and their relationship with lung cancer. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28253320 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333862 }} * {{medline-title |title=Circulating T helper and T regulatory subsets in untreated early rheumatoid arthritis and healthy control subjects. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27190305 |full-text-url=https://sci-hub.do/10.1189/jlb.5A0116-025R }} ==GAP43== * {{medline-title |title=HDAC inhibition leads to age-dependent opposite regenerative effect upon [[PTEN]] deletion in rubrospinal axons after SCI. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32171589 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.02.006 }} * {{medline-title |title=The Puzzling Role of Neuron-Specific PMCA Isoforms in the Aging Process. |date=16.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31888192 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941135 }} * {{medline-title |title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483 }} * {{medline-title |title=Differential expression of synaptic and interneuron genes in the aging human prefrontal cortex. |date=10.2018 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|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935443 }} * {{medline-title |title=Altered expression of hyperpolarization-activated cyclic nucleotide-gated channels and microRNA-1 and -133 in patients with age-associated atrial fibrillation. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26005035 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526032 }} * {{medline-title |title=Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse. |date=27.02.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761792 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352274 }} * {{medline-title |title=Association between reversal in the expression of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel and age-related atrial fibrillation. |date=14.11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25404650 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|title=Impact of Aging on the Phenotype of Invariant Natural Killer T Cells in Mouse Thymus. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33193368 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662090 }} * {{medline-title |title=Redox, immune and genetic biomarker system for personalized treatments in colorectal cancer. |date=15.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30788039 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379753 }} * {{medline-title |title=Low IL-2 Expressing T Cells in Thalassemia Major Patients: Is It Immune Aging. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30369736 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186253 }} * {{medline-title |title=Epigenetic repression of interleukin 2 expression in senescent CD4 T cells during chronic HIV type 1 infection. |date=01.01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25001463 |full-text-url=https://sci-hub.do/10.1093/infdis/jiu376 }} * {{medline-title |title=Cytomegalovirus infection modulates the phenotype and functional profile of the T-cell immune response to mycobacterial antigens in older life. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24370373 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003347 }} * {{medline-title |title=Propolis efficacy on [[TNF]]-α, IFN-γ and [[IL2]] cytokines production in old mice with and without systemic candidiasis. |date=09.2012 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23518081 |full-text-url=https://sci-hub.do/10.1016/j.mycmed.2012.05.004 }} * {{medline-title |title=The polyfunctionality of human memory CD8 T cells elicited by acute and chronic virus infections is not influenced by age. |date=2012 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23271970 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521721 }} ==KEAP1== * {{medline-title |title=Sex-, age-, and race/ethnicity-dependent variations in drug-processing and NRF2-regulated genes in human livers. |date=08.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33162398 |full-text-url=https://sci-hub.do/10.1124/dmd.120.000181 }} * {{medline-title |title=NRF2 pathway activation by [[KEAP1]] inhibition attenuates the manifestation of aging phenotypes in salivary glands. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32590331 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322188 }} * {{medline-title |title=Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds. |date=18.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32424161 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234996 }} * {{medline-title |title=Inflammatory and Senescent Phenotype of Pancreatic Stellate Cells Induced by Sqstm1 Downregulation Facilitates Pancreatic Cancer Progression. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182922 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535784 }} * {{medline-title |title=Systemic overexpression of [[SQSTM1]]/p62 accelerates disease onset in a [[SOD1]] -expressing ALS mouse model. |date=29.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29843805 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975400 }} * {{medline-title |title=Sulfur amino acid restriction-induced changes in redox-sensitive proteins are associated with slow protein synthesis rates. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29377163 |full-text-url=https://sci-hub.do/10.1111/nyas.13556 }} * {{medline-title |title=The Anti-Aging Effect of Erythropoietin via the ERK/Nrf2-ARE Pathway in Aging Rats. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28168414 |full-text-url=https://sci-hub.do/10.1007/s12031-017-0885-1 }} ==LRP1== * {{medline-title |title=Drug Targeting of Plasminogen Activator Inhibitor-1 Inhibits Metabolic Dysfunction and Atherosclerosis in a Murine Model of Metabolic Syndrome. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32268785 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255962 }} * {{medline-title |title=LXR activation protects hippocampal microvasculature in very old triple transgenic mouse model of Alzheimer's disease. |date=16.05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27057732 |full-text-url=https://sci-hub.do/10.1016/j.neulet.2016.04.007 }} * {{medline-title |title=Rescuing effects of RXR agonist bexarotene on aging-related synapse loss depend on neuronal [[LRP1]]. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26688581 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761336 }} * {{medline-title |title=Age-Related Decline in Brain and Hepatic Clearance of Amyloid-Beta is Rectified by the Cholinesterase Inhibitors Donepezil and Rivastigmine in Rats. |date=20.05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25782004 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receptor/nitric oxide pathway in immature female rats. |date=30.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31711775 |full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2019.109898 }} * {{medline-title |title=Genetic background, epigenetic factors and dietary interventions which influence human longevity. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31309340 |full-text-url=https://sci-hub.do/10.1007/s10522-019-09824-3 }} * {{medline-title |title=[[NOS3]] Inhibition Confers Post-Ischemic Protection to Young and Aging White Matter Integrity by Conserving Mitochondrial Dynamics and Miro-2 Levels. |date=11.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891729 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041791 }} * {{medline-title |title=[[NOS1]] and [[SNAP25]] polymorphisms are associated with Attention-Deficit/Hyperactivity Disorder symptoms in adults but not in children. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26821215 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{{medline-title |title=H19 is not hypomethylated or upregulated with age or sex in the aortic valves of mice. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31609547 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778597 }} * {{medline-title |title=Age-related remodelling of oesophageal epithelia by mutated cancer drivers. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30602793 |full-text-url=https://sci-hub.do/10.1038/s41586-018-0811-x }} * {{medline-title |title=Dynamic regulation of [[NOTCH1]] activation and Notch ligand expression in human thymus development. |date=13.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30042180 |full-text-url=https://sci-hub.do/10.1242/dev.165597 }} * {{medline-title |title=Long telomeres protect against age-dependent cardiac disease caused by [[NOTCH1]] haploinsufficiency. |date=01.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28346225 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409071 }} * {{medline-title |title=Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study. |date=09.04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27060904 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826550 }} * {{medline-title |title=Constitutive activation of [[NOTCH1]] signaling in Sertoli cells causes gonocyte exit from quiescence. |date=01.05.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23391689 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630254 }} ==NRAS== * {{medline-title |title=Senescent cholangiocytes release extracellular vesicles that alter target cell phenotype via the epidermal growth factor receptor. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32558183 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669612 }} * {{medline-title |title=[[STAT3]] Relays a Differential Response to Melanoma-Associated [i][[NRAS]][/i] Mutations. |date=02.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31906480 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016650 }} * {{medline-title |title=Cooperation of Dnmt3a R878H with Nras G12D promotes leukemogenesis in knock-in mice: a pilot study. |date=08.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31703632 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842226 }} * {{medline-title |title=Sequential acquisition of mutations in myelodysplastic syndromes. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821 |full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828 }} * {{medline-title |title=ETS Proto-oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin-dependent Kinase Inhibitor 2A. |date=24.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28184004 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377799 }} * {{medline-title |title=Trametinib radiosensitises RAS- and [[BRAF]]-mutated melanoma by perturbing cell cycle and inducing senescence. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26163092 |full-text-url=https://sci-hub.do/10.1016/j.radonc.2015.06.026 }} * {{medline-title |title=Registered report: senescence surveillance of pre-malignant hepatocytes limits liver cancer development. |date=26.01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25621566 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383234 }} ==NTS== * {{medline-title |title=Neuropeptide changes in the suprachiasmatic nucleus are associated with the development of hypertension. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31140326 |full-text-url=https://sci-hub.do/10.1080/07420528.2019.1613424 }} * {{medline-title |title=Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats. |date=01.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29518407 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|date=11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25042027 |full-text-url=https://sci-hub.do/10.1111/apha.12346 }} * {{medline-title |title=Chronic intermittent hypoxia promotes expression of 3-mercaptopyruvate sulfurtransferase in adult rat medulla oblongata. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24051007 |full-text-url=https://sci-hub.do/10.1016/j.autneu.2013.08.066 }} ==OGT== * {{medline-title |title=ELT-2 promotes O-GlcNAc transferase [[OGT]]-1 expression to modulate Caenorhabditis elegans lifespan. |date=06.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32628333 |full-text-url=https://sci-hub.do/10.1002/jcb.29817 }} * {{medline-title |title=Neuronal O-GlcNAcylation Improves Cognitive Function in the Aged Mouse Brain. |date=21.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31588002 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199460 }} * {{medline-title |title=Schwann cell O-GlcNAcylation promotes peripheral nerve remyelination 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{{medline-title |title=Association between lipoprotein (a) and proprotein convertase substilisin/kexin type 9 in patients with heterozygous familial hypercholesterolemia: A case-control study. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129821 |full-text-url=https://sci-hub.do/10.1016/j.metabol.2017.11.004 }} * {{medline-title |title=What's next for dyslipidemia management? The 2013 ACC/AHA Guidelines, the NLA recommendations, and beyond. |date=05-06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27156942 |full-text-url=https://sci-hub.do/10.1016/j.japh.2015.12.017 }} * {{medline-title |title=Impact of age and sex on the development of atherosclerosis and expression of the related genes in apoE deficient mice. |date=15.01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26592663 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.11.064 }} * {{medline-title |title=[[[[PC]]SK9]]: a key modulator of cardiovascular health. |date=14.03.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24625727 |full-text-url=https://sci-hub.do/10.1161/CIRCRESAHA.114.301621 }} ==PIK3CA== * {{medline-title |title=Catalog of Lung Cancer Gene Mutations Among Chinese Patients. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850378 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417348 }} * {{medline-title |title=Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/[[SIRT1]] pathway. |date=10.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182679 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594820 }} * {{medline-title |title=Oncogenic mutations in histologically normal endometrium: the new normal? |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187483 |full-text-url=https://sci-hub.do/10.1002/path.5314 }} * {{medline-title |title=A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30843125 |full-text-url=https://sci-hub.do/10.1007/s00595-019-01789-7 }} * {{medline-title |title=Membrane metallo-endopeptidase mediates cellular senescence induced by oncogenic [[PIK3CA]] accompanied with pro-tumorigenic secretome. |date=01.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30671946 |full-text-url=https://sci-hub.do/10.1002/ijc.32153 }} * {{medline-title |title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688 |full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003 }} * {{medline-title |title=Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26168237 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500567 }} ==PYY== * {{medline-title |title=Age- and diet-specific effects of chronic exposure to chlorpyrifos on hormones, inflammation and gut microbiota in rats. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31400786 |full-text-url=https://sci-hub.do/10.1016/j.pestbp.2019.05.018 }} * {{medline-title |title=Peptide YY ([[PYY]]) Is Expressed in Human Skeletal Muscle Tissue and Expanding Human Muscle Progenitor Cells. |date=2019 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|title=Increased peptide YY blood concentrations, not decreased acyl-ghrelin, are associated with reduced hunger and food intake in healthy older women: Preliminary evidence. |date=01.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27264721 |full-text-url=https://sci-hub.do/10.1016/j.appet.2016.06.002 }} * {{medline-title |title=Anorexigenic postprandial responses of [[PYY]] and GLP1 to slow ice cream consumption: preservation in obese adolescents, but not in obese adults. |date=03.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23239758 |full-text-url=https://sci-hub.do/10.1530/EJE-12-0867 }} ==RIPK3== * {{medline-title |title=Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3. |date=18.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33206046 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673785 }} * {{medline-title |title=Crucial role of the terminal complement complex in chondrocyte death and hypertrophy 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single nucleotide variants in the brain-derived neurotrophic factor ([[BDNF]]) and oxytocin receptor ([[OXTR]]) genes are associated with anxiety/depression in older women. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26175754 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485183 }} * {{medline-title |title=Role of the serotonin transporter gene locus in the response to SSRI treatment of major depressive disorder in late life. |date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25827644 |full-text-url=https://sci-hub.do/10.1177/0269881115578159 }} * {{medline-title |title=The Impact of Genetics on Physical Resilience and Successful Aging. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25818147 |full-text-url=https://sci-hub.do/10.1177/0898264315577586 }} * {{medline-title |title=Serotonin transporter polymorphism modifies the association between depressive symptoms and sleep onset latency complaint in elderly people: results from the 'InveCe.Ab' 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|title=Screening for a suitable cell membrane anchoring tag for Pseudomonas aeruginosa and applying it in cell membrane real-time tracking to investigate membrane aging. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32561163 |full-text-url=https://sci-hub.do/10.1016/j.mimet.2020.105984 }} * {{medline-title |title=Internalization of the [[TAT]]-[[PBX1]] fusion protein significantly enhances the proliferation of human hair follicle-derived mesenchymal stem cells and delays their senescence. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32436118 |full-text-url=https://sci-hub.do/10.1007/s10529-020-02909-x }} * {{medline-title |title=Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31024341 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467974 }} * {{medline-title |title=Effects of HIV-1 gp120 and [[TAT]]-derived microvesicles on endothelial cell function. |date=01.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789287 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589811 }} * {{medline-title |title=Sumoylation-deficient Prdx6 gains protective function by amplifying enzymatic activity and stability and escapes oxidative stress-induced aberrant Sumoylation. |date=05.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28055018 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386354 }} * {{medline-title |title=Characteristics, tissue-specific expression, and hormonal regulation of expression of tyrosine aminotransferase in the avian female reproductive tract. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27295280 |full-text-url=https://sci-hub.do/10.1016/j.domaniend.2016.05.001 }} * {{medline-title |title=Nanog induces suppression of senescence through downregulation of p27KIP1 expression. |date=01.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26795560 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|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326939 }} ==TRIM59== * {{medline-title |title=DNA methylation of the [[ELOVL2]], [[FHL2]], [[KLF14]], C1orf132/MIR29B2C, and [[TRIM59]] genes for age prediction from blood, saliva, and buccal swab samples. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30300865 |full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.09.010 }} * {{medline-title |title=Proof of concept study of age-dependent DNA methylation markers across different tissues by massive parallel sequencing. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30031222 |full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.07.007 }} * {{medline-title |title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467 |full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015 }} * {{medline-title |title=DNA methylation in 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|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2015.05.001 }} ==TSC1== * {{medline-title |title=[i]Tsc1[/i] Regulates the Proliferation Capacity of Bone-Marrow Derived Mesenchymal Stem Cells. |date=10.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32927859 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565438 }} * {{medline-title |title=mTORC1 underlies age-related muscle fiber damage and loss by inducing oxidative stress and catabolism. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30924297 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516169 }} * {{medline-title |title=[[FTO]] is involved in Alzheimer's disease by targeting [[TSC1]]-mTOR-Tau signaling. |date=25.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501742 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.02.201 }} * {{medline-title |title=Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent 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}} ==UCP3== * {{medline-title |title=Altered miRNA and mRNA Expression in Sika Deer Skeletal Muscle with Age. |date=06.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32041309 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073773 }} * {{medline-title |title=Age-related sex differences in the expression of important disease-linked mitochondrial proteins in mice. |date=05.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31806023 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896328 }} * {{medline-title |title=Integrated study on comparative transcriptome and skeletal muscle function in aged rats. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325930 |full-text-url=https://sci-hub.do/10.1016/j.mad.2018.01.001 }} * {{medline-title |title=Pleiotropic effects of [[UCP2]]-[[UCP3]] variability on leucocyte telomere length and glucose homeostasis. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28281015 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of rat brown adipose tissue prolonged the ovarian lifespan of aging mice by improving follicle survival. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31389140 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826128 }} * {{medline-title |title=Antioxidant hesperetin improves the quality of porcine oocytes during aging in vitro. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30358012 |full-text-url=https://sci-hub.do/10.1002/mrd.23079 }} * {{medline-title |title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model. |date=18.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463 }} * {{medline-title |title=Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25786490 |full-text-url=https://sci-hub.do/10.1071/RD14472 }} * {{medline-title |title=Interactions between genetic variants in [[AMH]] and [[[[AMH]]R2]] may modify age at natural menopause. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23544102 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609726 }} ==BRD4== * {{medline-title |title=Inhibition of [[BRD4]] triggers cellular senescence through suppressing aurora kinases in oesophageal cancer cells. |date=20.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32954665 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701500 }} * {{medline-title |title=[[BRD4]] contributes to LPS-induced macrophage senescence and promotes progression of atherosclerosis-associated lipid uptake. |date=11.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32392533 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288959 }} * {{medline-title |title=BET Proteins Are Required for Transcriptional Activation of the Senescent Islet Cell Secretome in Type 1 Diabetes. |date=26.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31561444 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801956 }} * {{medline-title |title=Interference with the bromodomain epigenome readers drives p21 expression and tumor senescence. |date=01.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31265875 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159039 }} * {{medline-title |title=Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872008 |full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.03.004 }} * {{medline-title |title=Bromodomain and Extraterminal Protein Inhibition Blocks Growth of Triple-negative Breast Cancers through the Suppression of Aurora Kinases. |date=04.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27650498 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095428 }} ==CCR6== * 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medicine and osteoporosis: a systematic review. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27873024 |full-text-url=https://sci-hub.do/10.1007/s00508-016-1125-3 }} * {{medline-title |title=Expression profile analysis of new candidate genes for the therapy of primary osteoporosis. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26914116 }} ==CYP11A1== * {{medline-title |title=Prepubertal exposure to perfluorononanoic acid interferes with spermatogenesis and steroidogenesis in male mice. |date=15.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576894 |full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.12.034 }} * {{medline-title |title=Morphological rearrangement of the cortical region, in aging ovaries. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30589059 |full-text-url=https://sci-hub.do/10.14670/HH-18-078 }} * {{medline-title |title=Peroxiredoxin 2 deficiency accelerates age-related ovarian failure through the reactive oxygen species-mediated JNK pathway in mice. |date=01.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29778464 |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.05.059 }} * {{medline-title |title=Systemic analysis of gene expression profiles in porcine granulosa cells during aging. |date=14.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228554 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722506 }} * {{medline-title |title=Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio). |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29197246 |full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.11.128 }} * {{medline-title |title=Testicular gene expression of steroidogenesis-related factors in prepubertal, postpubertal, and aging dogs. |date=01.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28166986 |full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2016.11.007 }} ==CYP17A1== * {{medline-title |title=Intratumoral heterogeneity of the tumor cells based on in situ cortisol excess in cortisol-producing adenomas; ∼An association among morphometry, genotype and cellular senescence∼. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33002589 |full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2020.105764 }} * {{medline-title |title=Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio). |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29197246 |full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.11.128 }} * {{medline-title |title=Testicular gene expression of steroidogenesis-related factors in prepubertal, postpubertal, and aging dogs. |date=01.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28166986 |full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2016.11.007 }} * {{medline-title |title=[[CYP17A1]] Enzyme Activity Is Linked to Ambulatory Blood Pressure in a Family-Based Population Study. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26297028 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886492 }} * {{medline-title |title=Sequence analysis of six blood pressure candidate regions in 4,178 individuals: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25275628 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183565 }} * {{medline-title |title=Of mice and men--warning: intact versus castrated adult male mice as xenograft hosts are equivalent to hypogonadal versus abiraterone treated aging human males, respectively. |date=09.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23775398 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009979 }} ==DKK1== * {{medline-title |title=Low Serum Levels of [[DKK2]] Predict Incident Low-Impact Fracture in Older Women. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31372588 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659448 }} * {{medline-title |title=Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling. |date=11.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31080114 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565990 }} * {{medline-title |title=[Role and alterations of DNA methylation during the aging and cancer]. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647 |full-text-url=https://sci-hub.do/10.1556/650.2018.30927 }} * {{medline-title |title=Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-[[FOXO1]] pathway. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28507478 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427465 }} * {{medline-title |title=Circulating sclerostin and dickkopf-1 levels in ossification of the posterior longitudinal ligament of the spine. |date=05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26040409 |full-text-url=https://sci-hub.do/10.1007/s00774-015-0671-5 }} * {{medline-title |title=Vaccination with [[DKK1]]-derived peptides promotes bone formation and bone mass in an aged mouse osteoporosis model. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24907907 |full-text-url=https://sci-hub.do/10.1007/s00223-014-9875-2 }} ==FGF19== * {{medline-title |title=Bile acid receptor agonists in primary biliary cholangitis: Regulation of the cholangiocyte secretome and downstream T cell differentiation. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32123836 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996327 }} * {{medline-title |title=Kotho and aging. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30557478 }} * {{medline-title |title=The Klotho proteins in health and disease. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30455427 |full-text-url=https://sci-hub.do/10.1038/s41581-018-0078-3 }} * {{medline-title |title=Peroxisomal Acyl-CoA Oxidase Type 1: Anti-Inflammatory and Anti-Aging Properties with a Special Emphasis on Studies with LPS and Argan Oil as a Model Transposable to Aging. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29765501 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889864 }} * {{medline-title |title=A Genetic Screen Identifies Hypothalamic Fgf15 as a Regulator of Glucagon Secretion. |date=08.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27829151 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120348 }} * {{medline-title |title=A preliminary candidate approach identifies the combination of chemerin, fetuin-A, and fibroblast growth factors 19 and 21 as a potential biomarker panel of successful aging. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25911468 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409588 }} ==GCLM== * {{medline-title |title=Silencing Bach1 alters aging-related changes in the expression of Nrf2-regulated genes in primary human bronchial epithelial cells. |date=15.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31422075 |full-text-url=https://sci-hub.do/10.1016/j.abb.2019.108074 }} * {{medline-title |title=Ontogeny and aging of Nrf2 pathway genes in livers of rats. |date=15.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29689272 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2018.04.018 }} * {{medline-title |title=Sulfur amino acid restriction-induced changes in redox-sensitive proteins are associated with slow protein synthesis rates. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29377163 |full-text-url=https://sci-hub.do/10.1111/nyas.13556 }} * {{medline-title |title=Aging-related decline in the induction of Nrf2-regulated antioxidant genes in human bronchial epithelial cells. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28863281 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576992 }} * {{medline-title |title=Nrf2 signaling is impaired in the aging [[RPE]] given an oxidative insult. |date=02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24216314 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946784 }} * {{medline-title |title=Competition of nuclear factor-erythroid 2 factors related transcription factor isoforms, Nrf1 and Nrf2, in antioxidant enzyme induction. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24024152 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757680 }} ==GEM== * {{medline-title |title=The Impact of Geriatric Emergency Management Nurses on the Care of Frail Older Patients in the Emergency Department: a Systematic Review. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32904804 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458600 }} * {{medline-title |title=Cytosolic and mitochondrial Ca concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553 |full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055 }} * {{medline-title |title=Understanding of diagnosis and medications among non-English-speaking older patients. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29377482 |full-text-url=https://sci-hub.do/10.1111/ajag.12503 }} * {{medline-title |title=Increased gait variability may not imply impaired stride-to-stride control of walking in healthy older adults: Winner: 2013 Gait and Clinical Movement Analysis Society Best Paper Award. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28454071 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869351 }} * {{medline-title |title=The development and evaluation of mini-[[GEM]]s - short, focused, online e-learning videos in geriatric medicine. |date=04-06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27050439 |full-text-url=https://sci-hub.do/10.1080/02701960.2016.1165217 }} * {{medline-title |title=Neoplastic and nonneoplastic lesions in aging mice of unique and common inbred strains contribution to modeling of human neoplastic diseases. |date=05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24019352 |full-text-url=https://sci-hub.do/10.1177/0300985813501334 }} ==GLS== * {{medline-title |title=Normal Values and Growth-Related Changes of Left Ventricular Volumes, Stress, and Strain in Healthy Children Measured by 3-Dimensional Echocardiography. |date=15.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29784576 |full-text-url=https://sci-hub.do/10.1016/j.amjcard.2018.03.355 }} * {{medline-title |title=Future Perspectives for Management of Stage A Heart Failure. |date=01.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29731506 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055033 }} * {{medline-title |title=Reference Ranges of Left Ventricular Strain Measures by Two-Dimensional Speckle-Tracking Echocardiography in Children: A Systematic Review and Meta-Analysis. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26747685 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779733 }} * {{medline-title |title=Cardiorespiratory fitness modifies the relationship between myocardial function and cerebral blood flow in older adults. |date=01.05.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26032886 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029275 }} * {{medline-title |title=Left ventricular strain examination of different aged adults with 3D speckle tracking echocardiography. |date=03.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24028413 |full-text-url=https://sci-hub.do/10.1111/echo.12367 }} * {{medline-title |title=Left ventricular three-dimensional global systolic strain by real-time three-dimensional speckle-tracking in children: feasibility, reproducibility, maturational changes, and normal ranges. |date=08.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23791113 |full-text-url=https://sci-hub.do/10.1016/j.echo.2013.05.002 }} ==GSTP1== * {{medline-title |title=DCAF1 regulates Treg senescence via the ROS axis during immunological aging. |date=02.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32730228 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598062 }} * {{medline-title |title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684 }} * {{medline-title |title=Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27584680 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008632 }} * {{medline-title |title=Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway. |date=04.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462499 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050201 }} * {{medline-title |title=Epigenetic susceptibility factors for prostate cancer with aging. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23999928 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237278 }} * {{medline-title |title=The age-related change of glutathione antioxidant system in mice liver. |date=07.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23343351 |full-text-url=https://sci-hub.do/10.3109/15376516.2013.769655 }} ==HAL== * {{medline-title |title=Comparison of haloperidol, non-haloperidol antipsychotics, and no pharmacotherapy for the management of delirium in an inpatient geriatric palliative care population. |date=06-09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31066639 |full-text-url=https://sci-hub.do/10.1080/15360288.2018.1513434 }} * {{medline-title |title=Acute and long-term effects of haloperidol on surgery-induced neuroinflammation and cognitive deficits in aged rats. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31049689 |full-text-url=https://sci-hub.do/10.1007/s00540-019-02646-0 }} * {{medline-title |title=Histone deacetylase inhibitors reverse age-related increases in side effects of haloperidol in mice. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28421257 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538925 }} * {{medline-title |title=Differential effects of intermittent versus continuous haloperidol treatment throughout adolescence on haloperidol sensitization and social behavior in adulthood. |date=03.10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24942467 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134967 }} * {{medline-title |title=HDAC inhibitors restore the capacity of aged mice to respond to haloperidol through modulation of histone acetylation. |date=05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24366052 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988551 }} * {{medline-title |title=Selective matrix (hyaluronan) interaction with [[CD44]] and RhoGTPase signaling promotes keratinocyte functions and overcomes age-related epidermal dysfunction. |date=10.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23790635 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775883 }} ==HBP1== * {{medline-title |title=Suppression of p38/[[HBP1]] pathway alleviates hyperosmotic stress-induced senescent progression of chondrocyte senescence. |date=03-04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32549582 |full-text-url=https://sci-hub.do/10.23812/20-63-A-6 }} * {{medline-title |title=Transcription factor [[HBP1]]: A regulator of senescence and apoptosis of preadipocytes. |date=17.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331641 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.07.048 }} * {{medline-title |title=A positive feedback loop between Pim-1 kinase and [[HBP1]] transcription factor contributes to hydrogen peroxide-induced premature senescence and apoptosis. |date=19.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28348080 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437229 }} * {{medline-title |title=Focused screening of mitochondrial metabolism reveals a crucial role for a tumor suppressor Hbp1 in ovarian reserve. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27206316 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041189 }} * {{medline-title |title=[[HBP1]]-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/[[EZH2]] Pathways and Its Impact on Cell Senescence and Tumorigenesis. |date=10.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27129219 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933444 }} * {{medline-title |title=Absence of AMPKα2 accelerates cellular senescence via p16 induction in mouse embryonic fibroblasts. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26718972 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720555 }} ==HCN1== * {{medline-title |title=Protein expression changes of [[HCN1]] and [[HCN2]] in hippocampal subregions of gerbils during the normal aging process. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32128096 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038419 }} * {{medline-title |title=HCN as a Mediator of Urinary Homeostasis: Age-Associated Changes in Expression and Function in Adrenergic Detrusor Relaxation. |date=15.02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30124776 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376092 }} * {{medline-title |title=Dopaminergic Neurons Exhibit an Age-Dependent Decline in Electrophysiological Parameters in the MitoPark Mouse Model of Parkinson's Disease. |date=06.04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27053209 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821912 }} * {{medline-title |title=Characteristics of hyperpolarization-activated cyclic nucleotide-gated channels in dorsal root ganglion neurons at different ages and sizes. |date=11.11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26379059 |full-text-url=https://sci-hub.do/10.1097/WNR.0000000000000455 }} * {{medline-title |title=Age-associated expression of HCN channel isoforms in rat sinoatrial node. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26341471 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935443 }} * {{medline-title |title=Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse. |date=27.02.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761792 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352274 }} ==HDAC6== * {{medline-title |title=Inhibition of [[HDAC6]] Attenuates Diabetes-Induced Retinal Redox Imbalance and Microangiopathy. |date=09.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32660051 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402090 }} * {{medline-title |title=Cellular senescence is associated with reorganization of the microtubule cytoskeleton. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30599068 |full-text-url=https://sci-hub.do/10.1007/s00018-018-2999-1 }} * {{medline-title |title=2,4‑Di‑tert‑butylphenol, a potential [[HDAC6]] inhibitor, induces senescence and mitotic catastrophe in human gastric adenocarcinoma AGS cells. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29427610 |full-text-url=https://sci-hub.do/10.1016/j.bbamcr.2018.02.003 }} * {{medline-title |title=[[HDAC6]] Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of [[PLIN2]] in Drosophila. |date=09.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28966044 |full-text-url=https://sci-hub.do/10.1016/j.devcel.2017.09.001 }} * {{medline-title |title=The Deacetylase [[HDAC6]] Mediates Endogenous Neuritic Tau Pathology. |date=29.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854366 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578720 }} * {{medline-title |title=Declined Expression of Histone Deacetylase 6 Contributes to Periodontal Ligament Stem Cell Aging. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27562218 |full-text-url=https://sci-hub.do/10.1902/jop.2016.160338 }} ==HMGA2== * {{medline-title |title=4D Genome Rewiring during Oncogene-Induced and Replicative Senescence. |date=07.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32220303 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208559 }} * {{medline-title |title=The protective effects of [[HMGA2]] in the senescence process of bone marrow-derived mesenchymal stromal cells. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32068957 |full-text-url=https://sci-hub.do/10.1002/term.3023 }} * {{medline-title |title=Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells. |date=05.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30194939 |full-text-url=https://sci-hub.do/10.1016/j.ejphar.2018.09.005 }} * {{medline-title |title=Molecular differences between stromal cell populations from deciduous and permanent human teeth. |date=18.04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25927523 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417277 }} * {{medline-title |title=Rb protein is essential to the senescence-associated heterochromatic foci formation induced by [[HMGA2]] in primary WI38 cells. |date=20.08.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23969248 |full-text-url=https://sci-hub.do/10.1016/j.jgg.2013.05.007 }} * {{medline-title |title=MYCN/[[LIN28B]]/Let-7/[[HMGA2]] pathway implicated by meta-analysis of GWAS in suppression of post-natal proliferation thereby potentially contributing to aging. |date=07-08.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23639551 |full-text-url=https://sci-hub.do/10.1016/j.mad.2013.04.006 }} ==HMGB2== * {{medline-title |title=Loss of Endogenous [[HMGB2]] Promotes Cardiac Dysfunction and Pressure Overload-Induced Heart Failure in Mice. |date=25.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30487376 |full-text-url=https://sci-hub.do/10.1253/circj.CJ-18-0925 }} * {{medline-title |title=[[HMGB2]] Loss upon Senescence Entry Disrupts Genomic Organization and Induces [[CTCF]] Clustering across Cell Types. |date=17.05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29706538 |full-text-url=https://sci-hub.do/10.1016/j.molcel.2018.03.030 }} * {{medline-title |title=Correlations between age, functional status, and the senescence-associated proteins [[HMGB2]] and p16 . |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29651745 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964056 }} * {{medline-title |title=Transcriptional Repression of High-Mobility Group Box 2 by p21 in Radiation-Induced Senescence. |date=30.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487276 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935093 }} * {{medline-title |title=Loss of Endometrial Plasticity in Recurrent Pregnancy Loss. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26418742 |full-text-url=https://sci-hub.do/10.1002/stem.2222 }} * {{medline-title |title=Quantitative proteomic profiling of tumor cell response to telomere dysfunction using isotope-coded protein labeling (ICPL) reveals interaction network of candidate senescence markers. |date=08.10.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23969227 |full-text-url=https://sci-hub.do/10.1016/j.jprot.2013.08.007 }} ==IGF2== * {{medline-title |title=Paternal Insulin-like Growth Factor 2 (Igf2) Regulates Stem Cell Activity During Adulthood. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28007480 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233811 }} * {{medline-title |title=Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27294501 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983298 }} * {{medline-title |title=Autocrine Action of [[IGF2]] Regulates Adult β-Cell Mass and Function. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26384384 |full-text-url=https://sci-hub.do/10.2337/db14-1735 }} * {{medline-title |title=Enhanced memory consolidation in mice lacking the circadian modulators Sharp1 and -2 caused by elevated Igf2 signaling in the cortex. |date=07.07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26100875 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500222 }} * {{medline-title |title=miR-30e targets [[IGF2]]-regulated osteogenesis in bone marrow-derived mesenchymal stem cells, aortic smooth muscle cells, and ApoE-/- mice. |date=01.04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25678587 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375408 }} * {{medline-title |title=Epigenetic susceptibility factors for prostate cancer with aging. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23999928 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237278 }} ==IL4== * {{medline-title |title=Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia. |date=01.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29122767 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756472 }} * {{medline-title |title=Aging Affects Bone Marrow Macrophage Polarization: Relevance to Bone Healing. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28138512 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270653 }} * {{medline-title |title=[[IL4]]/[[STAT6]] Signaling Activates Neural Stem Cell Proliferation and Neurogenesis upon Amyloid-β42 Aggregation in Adult Zebrafish Brain. |date=18.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27760324 |full-text-url=https://sci-hub.do/10.1016/j.celrep.2016.09.075 }} * {{medline-title |title=[[IL10]]-driven [[STAT3]] signalling in senescent macrophages promotes pathological eye angiogenesis. |date=11.08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26260587 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918330 }} * {{medline-title |title=LIPID PROFILE AND CYTOKINES INTERACTIONS DURING SUCCESSFUL AGING. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26087730 }} * {{medline-title |title=Ageing related periostin expression increase from cardiac fibroblasts promotes cardiomyocytes senescent. |date=26.09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25173938 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2014.08.109 }} ==IRF8== * {{medline-title |title=Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33112891 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592753 }} * {{medline-title |title=Hyperglycemia-induced inflamm-aging accelerates gingival senescence via [[NLRC4]] phosphorylation. |date=06.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31676687 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901307 }} * {{medline-title |title=[[IRF8]] induces senescence of lung cancer cells to exert its tumor suppressive function. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31594449 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927690 }} * {{medline-title |title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. |date=10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812 }} * {{medline-title |title=Aging impairs both primary and secondary [[RIG]]-I signaling for interferon induction in human monocytes. |date=12.12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29233916 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429941 }} * {{medline-title |title=Microglia recapitulate a hematopoietic master regulator network in the aging human frontal cortex. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26002684 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503803 }} ==JAK1== * {{medline-title |title=Implication of [[JAK1]]/[[STAT3]]/[[SOCS3]] Pathway in Aging of Cerebellum of Male Rat: Histological and Molecular study. |date=01.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32483368 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264275 }} * {{medline-title |title=Irradiation-induced senescence of bone marrow mesenchymal stem cells aggravates osteogenic differentiation dysfunction via paracrine signaling. |date=01.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32233952 |full-text-url=https://sci-hub.do/10.1152/ajpcell.00520.2019 }} * {{medline-title |title=The Upregulation of Toll-Like Receptor 3 via Autocrine IFN-β Signaling Drives the Senescence of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Through [[JAK1]]. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396213 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6665952 }} * {{medline-title |title=Influence of age and renal impairment on the steady state pharmacokinetics of filgotinib, a selective [[JAK1]] inhibitor. |date=12.2018 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reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171024 |full-text-url=https://sci-hub.do/10.1002/jcp.26231 }} * {{medline-title |title=Comparison of Changes in the Interstitial Cells of Cajal and Neuronal Nitric Oxide Synthase-positive Neuronal Cells With Aging Between the Ascending and Descending Colon of F344 Rats. |date=30.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28774159 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628993 }} * {{medline-title |title=Leukocyte telomere length in mastocytosis: correlations with depression and perceived stress. |date=01.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23917070 |full-text-url=https://sci-hub.do/10.1016/j.bbi.2013.07.009 }} * {{medline-title |title=Changes of number of cells expressing proliferation and progenitor cell markers with age in rabbit intervertebral discs. |date=05.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23449074 |full-text-url=https://sci-hub.do/10.1093/abbs/gmt019 }} * {{medline-title |title=Systemic mastocytosis in the elderly. |date=05.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23436294 |full-text-url=https://sci-hub.do/10.1002/ajh.23426 }} ==LAMP2== * {{medline-title |title=An In-Vitro Cell Model of Intracellular Protein Aggregation Provides Insights into [[RPE]] Stress Associated with Retinopathy. |date=11.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32932802 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555953 }} * {{medline-title |title=Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells. |date=01.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32244623 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235898 }} * {{medline-title |title=Genetic [[LAMP2]] deficiency accelerates the age-associated formation of basal laminar deposits in the retina. |date=19.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31699817 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876195 }} * {{medline-title |title=[[SQSTM1]]/p62 and [[PPARGC1A]]/PGC-1alpha at the interface of autophagy and vascular senescence. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31441382 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469683 }} * {{medline-title |title=A pH probe inhibits senescence in mesenchymal stem cells. |date=07.12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526663 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286523 }} * {{medline-title |title=Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203401 |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.022 }} ==MAPK1== * {{medline-title |title=Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850814 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413062 }} * {{medline-title |title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. |date=15.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220 |full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063 }} * {{medline-title |title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201 }} * {{medline-title |title=iTRAQ-based proteomic profiling of granulosa cells from lamb and ewe after superstimulation. |date=01.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28708522 |full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2017.06.014 }} * {{medline-title |title=Crosstalk from cAMP to ERK1/2 emerges during postnatal maturation of nociceptive neurons and is maintained during aging. |date=01.07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28515230 |full-text-url=https://sci-hub.do/10.1242/jcs.197327 }} * {{medline-title |title=Maternal immune activation induces changes in myelin and metabolic proteins, some of which can be prevented with risperidone in adolescence. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25592202 |full-text-url=https://sci-hub.do/10.1159/000368305 }} ==MCU== * {{medline-title |title=A rare case of Epstein-Barr virus-positive mucocutaneous ulcer that developed into an intestinal obstruction: a case report. |date=13.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31931725 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958744 }} * {{medline-title |title=Inhibition of Mitochondrial Calcium Overload by [[SIRT3]] Prevents Obesity- or Age-Related Whitening of Brown Adipose Tissue. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31712319 |full-text-url=https://sci-hub.do/10.2337/db19-0526 }} * {{medline-title |title=Cytosolic and mitochondrial Ca concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553 |full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055 }} * {{medline-title |title=The nuclear receptor [[RXRA]] controls cellular senescence by regulating calcium signaling. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216632 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260923 }} * {{medline-title |title=Physical exercise in aging human skeletal muscle increases mitochondrial calcium uniporter expression levels and affects mitochondria dynamics. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28039397 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with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study. |date=01.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27616567 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837042 }} * {{medline-title |title=Dynamic Phosphorylation of the Myocyte Enhancer Factor 2Cα1 Splice Variant Promotes Skeletal Muscle Regeneration and Hypertrophy. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27612437 |full-text-url=https://sci-hub.do/10.1002/stem.2495 }} * {{medline-title |title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889 }} * {{medline-title |title=Postnatal expression patterns and polymorphism analysis of the bovine myocyte enhancer factor 2C (Mef2C) gene. |date=12.2014 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longitudinal changes of parameters in rabbit VX2 liver tumors. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26878263 |full-text-url=https://sci-hub.do/10.1002/jmri.25179 }} * {{medline-title |title=[Expression of vascular endothelial growth factor and microvessel density in different brain regions in aged rats]. |date=07.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25080903 |full-text-url=https://sci-hub.do/10.11817/j.issn.1672-7347.2014.07.005 }} ==NDUFB8== * {{medline-title |title=Older Adults with Physical Frailty and Sarcopenia Show Increased Levels of Circulating Small Extracellular Vesicles with a Specific Mitochondrial Signature. |date=15.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32326435 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227017 }} * {{medline-title |title=Mitochondrial Signatures in Circulating Extracellular Vesicles of Older Adults with Parkinson's Disease: Results from the EXosomes in PArkiNson's Disease (EXPAND) Study. 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}} * {{medline-title |title=Reduced levels of mitochondrial complex I subunit [[NDUFB8]] and linked complex I III oxidoreductase activity in the TgCRND8 mouse model of Alzheimer's disease. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24217272 |full-text-url=https://sci-hub.do/10.3233/JAD-131499 }} ==NF1== * {{medline-title |title=Conditional reprograming culture conditions facilitate growth of lower grade glioma models. |date=01.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33258947 |full-text-url=https://sci-hub.do/10.1093/neuonc/noaa263 }} * {{medline-title |title=Circular RNA [[NF1]]-419 enhances autophagy to ameliorate senile dementia by binding Dynamin-1 and Adaptor protein 2 B1 in AD-like mice. |date=20.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31860870 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949063 }} * {{medline-title |title=[[NF1]] loss induces senescence during human melanocyte differentiation in an iPSC-based model. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25824590 |full-text-url=https://sci-hub.do/10.1111/pcmr.12369 }} * {{medline-title |title=TGF-β/[[NF1]]/Smad4-mediated suppression of ANT2 contributes to oxidative stress in cellular senescence. |date=12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25220407 |full-text-url=https://sci-hub.do/10.1016/j.cellsig.2014.08.029 }} * {{medline-title |title=Neuropsychological impairments in elderly Neurofibromatosis type 1 patients. |date=04.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24556498 |full-text-url=https://sci-hub.do/10.1016/j.ejmg.2014.02.004 }} * {{medline-title |title=Long-term prognosis of patients with pediatric pheochromocytoma. |date=02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24169644 |full-text-url=https://sci-hub.do/10.1530/ERC-13-0415 }} ==NOS3== * {{medline-title |title=Application of Oxidative Stress to a Tissue-Engineered Vascular Aging Model Induces Endothelial Cell Senescence and Activation. |date=22.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32455928 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290800 }} * {{medline-title |title=Hypertension and longevity: role of genetic polymorphisms in renin-angiotensin-aldosterone system and endothelial nitric oxide synthase. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30460536 |full-text-url=https://sci-hub.do/10.1007/s11010-018-3470-1 }} * {{medline-title |title=[[NOS3]] Inhibition Confers Post-Ischemic Protection to Young and Aging White Matter Integrity by Conserving Mitochondrial Dynamics and Miro-2 Levels. |date=11.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891729 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041791 }} * {{medline-title |title=Vascular senescence and ageing: a role for the MEOX proteins in promoting endothelial dysfunction. |date=10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28727928 |full-text-url=https://sci-hub.do/10.1139/cjpp-2017-0149 }} * {{medline-title |title=Fetal programming of blood pressure in a transgenic mouse model of altered intrauterine environment. |date=01.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27506899 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134377 }} * {{medline-title |title=Common polymorphisms in nitric oxide synthase (NOS) genes influence quality of aging and longevity in humans. |date=04.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23572278 |full-text-url=https://sci-hub.do/10.1007/s10522-013-9421-z }} ==NPR1== * {{medline-title |title=The [[NPR1]]-WRKY46-WRKY6 signaling cascade mediates probenazole/salicylic acid-elicited leaf senescence in Arabidopsis thaliana. |date=03.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33270345 |full-text-url=https://sci-hub.do/10.1111/jipb.13044 }} * {{medline-title |title=Loss of proton/calcium exchange 1 results in the activation of plant defense and accelerated senescence in Arabidopsis. |date=07.2020 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dissection of the effects of ethylene, H2O2 and high irradiance on antioxidants and several genes associated with stress and senescence in tobacco leaves. |date=15.02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24119414 |full-text-url=https://sci-hub.do/10.1016/j.jplph.2013.08.007 }} ==NRK== * {{medline-title |title=[Molecular mechanisms of mycelium of Cordyceps sinensis ameliorating renal tubular epithelial cells aging induced by D-galactose via inhibiting autophagy-related AMPK/[[ULK1]] signaling activation]. |date=03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30989992 |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20181205.001 }} * {{medline-title |title=Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-[[ULK1]] signaling-mediated autophagy. |date=24.12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585174 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326678 }} * {{medline-title |title=Fascin2 regulates cisplatin-induced apoptosis in [[NRK]]-52E cells. |date=15.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27989596 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074922 }} * {{medline-title |title=2,3,5,4'-Tetrahydroxystilbene-2-O-[i]β[/i]-D-glucoside Promotes Expression of the Longevity Gene Klotho. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27885332 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112329 }} * {{medline-title |title=A role for the age-dependent loss of α(E)-catenin in regulation of N-cadherin expression and cell migration. |date=01.06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24920123 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208646 }} * {{medline-title |title=Overexpression of MMP-7 Increases Collagen 1A2 in the Aging Kidney. |date=10.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24273653 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834982 }} ==PAK1== * {{medline-title |title=1,2,3-Triazolyl ester of ketorolac (15K): Boosting both heat-endurance and lifespan of C. elegans by down-regulating [[PAK1]] at nM levels. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760342 |full-text-url=https://sci-hub.do/10.5582/ddt.2018.01018 }} * {{medline-title |title=From bench (laboratory) to bed (hospital/home): How to explore effective natural and synthetic [[PAK1]]-blockers/longevity-promoters for cancer therapy. |date=15.12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28814374 |full-text-url=https://sci-hub.do/10.1016/j.ejmech.2017.07.043 }} * {{medline-title |title=Effect of Okinawa Propolis on [[PAK1]] Activity, Caenorhabditis elegans Longevity, Melanogenesis, and Growth of Cancer Cells. |date=13.07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27337169 |full-text-url=https://sci-hub.do/10.1021/acs.jafc.6b01785 }} * {{medline-title |title=Several herbal compounds in Okinawa plants directly inhibit the oncogenic/aging kinase [[PAK1]]. |date=12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25639302 |full-text-url=https://sci-hub.do/10.5582/ddt.2014.01045 }} * {{medline-title |title=Herbal therapeutics that block the oncogenic kinase [[PAK1]]: a practical approach towards [[PAK1]]-dependent diseases and longevity. |date=05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23943274 |full-text-url=https://sci-hub.do/10.1002/ptr.5054 }} * {{medline-title |title=[[PAK1]]-deficiency/down-regulation reduces brood size, activates HSP16.2 gene and extends lifespan in Caenorhabditis elegans. |date=02.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23524941 |full-text-url=https://sci-hub.do/10.5582/ddt.2013.v7.1.29 }} ==PGP== * {{medline-title |title=Age-associated changes of the intrinsic nervous system in relation with interstitial cells in the pre-weaning goat rumen. |date=14.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31305258 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660047 }} * {{medline-title |title=Changes in the interstitial cells of Cajal and neuronal nitric oxide synthase positive neuronal cells with aging in the esophagus of F344 rats. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29182640 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705109 }} * {{medline-title |title=Change in the Interstitial Cells of Cajal and nNOS Positive Neuronal Cells with Aging in the Stomach of F344 Rats. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28045993 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207530 }} * {{medline-title |title=The matrikine N-acetylated proline-glycine-proline induces premature senescence of nucleus pulposus cells via [[CXCR1]]-dependent ROS accumulation and DNA damage and reinforces the destructive effect of these cells on homeostasis of intervertebral discs. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27769935 |full-text-url=https://sci-hub.do/10.1016/j.bbadis.2016.10.011 }} * {{medline-title |title=[CHANGES IN [[TH]]E PANCREATIC ISLETS AND NERVOUS ELEMENTS IN RATS DURING AGING (AN IMMUNOHISTOCHEMICAL STUDY)]. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27141588 }} * {{medline-title |title=Associations between xerostomia, histopathological alterations, and autonomic innervation of labial salivary glands in men in late midlife. |date=09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24905142 |full-text-url=https://sci-hub.do/10.1016/j.exger.2014.06.004 }} ==POR== * {{medline-title |title=The Ventricular System Enlarges Abnormally in the Seventies, Earlier in Men, and First in the Frontal Horn: A Study Based on More Than 3,000 Scans. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31749695 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848156 }} * {{medline-title |title=Clinical findings associated with development of postoperative reflux and short-term survival after small intestinal surgery in geriatric and mature nongeriatric horses. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31002397 |full-text-url=https://sci-hub.do/10.1111/vsu.13217 }} * {{medline-title |title=Effect of Age and Allele Variants of [[CYP3A5]], [[CYP3A4]], and [[POR]] Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135906 |full-text-url=https://sci-hub.do/10.1097/FTD.0000000000000442 }} * {{medline-title |title=Phosphorylation of WHIRLY1 by CIPK14 Shifts Its Localization and Dual Functions in Arabidopsis. |date=01.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28412544 |full-text-url=https://sci-hub.do/10.1016/j.molp.2017.03.011 }} * {{medline-title |title=Endometriosis has no negative impact on outcomes of in vitro fertilisation in women with poor ovarian response. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27627604 |full-text-url=https://sci-hub.do/10.1111/1471-0528.14018 }} * {{medline-title |title=Short-term complications after colic surgery in geriatric versus mature non-geriatric horses. |date=02.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25289944 |full-text-url=https://sci-hub.do/10.1111/j.1532-950X.2014.12281.x }} ==POT1== * {{medline-title |title=Decreased expression of [[TERT]] and telomeric proteins as human ovaries age may cause telomere shortening. |date=27.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32856217 |full-text-url=https://sci-hub.do/10.1007/s10815-020-01932-1 }} * {{medline-title |title=MiR-185 targets [[POT1]] to induce telomere dysfunction and cellular senescence. |date=18.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32687062 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425516 }} * {{medline-title |title=Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. |date=05.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32109421 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058826 }} * {{medline-title |title=Seryl tRNA synthetase cooperates with [[POT1]] to regulate telomere length and cellular senescence. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31815007 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882858 }} * {{medline-title |title=A newly identified berberine derivative induces cancer cell senescence by stabilizing endogenous G-quadruplexes and sparking a DNA damage response at the telomere region. |date=03.11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26462146 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742130 }} * {{medline-title |title=Caenorhabditis elegans POT-1 and POT-2 repress telomere maintenance pathways. |date=02.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23390606 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564990 }} ==PRC1== * {{medline-title |title=Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development. |date=24.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32979540 |full-text-url=https://sci-hub.do/10.1016/j.bone.2020.115659 }} * {{medline-title |title=Timosaponin A-III inhibits oncogenic phenotype via regulation of PcG protein [[BMI1]] in breast cancer cells. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29528145 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986597 }} * {{medline-title |title=Epigenetic factors Polycomb (Pc) and Suppressor of zeste (Su(z)2) negatively regulate longevity in Drosophila melanogaster. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177687 |full-text-url=https://sci-hub.do/10.1007/s10522-017-9737-1 }} * {{medline-title |title=The Polycomb Group Protein Pcgf1 Is Dispensable in Zebrafish but Involved in Early Growth and Aging. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27442247 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956247 }} * {{medline-title |title=[[CBX7]] and miR-9 are part of an autoregulatory loop controlling p16(INK) (4a). |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26416703 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693451 }} * {{medline-title |title=Mitogen-activated protein kinase signaling mediates phosphorylation of polycomb ortholog Cbx7. |date=20.12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24194518 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868753 }} ==PROC== * {{medline-title |title=Does midlife aging impact women's sleep duration, continuity, and timing?: A longitudinal analysis from the Study of Women's Health Across the Nation. |date=15.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31633180 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157190 }} * {{medline-title |title=Effects of feeding frequency of an elevated plane of milk replacer and calf age on behavior, and glucose and insulin kinetics in male Holstein calves. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30419975 |full-text-url=https://sci-hub.do/10.1017/S175173111800294X }} * {{medline-title |title=Age-related effects on markers of inflammation and cartilage metabolism in response to an intra-articular lipopolysaccharide challenge in horses. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28380609 |full-text-url=https://sci-hub.do/10.2527/jas.2016.1078 }} * {{medline-title |title=Normative data for rotational chair stratified by age. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26227880 |full-text-url=https://sci-hub.do/10.1002/lary.25497 }} * {{medline-title |title=Day-to-Day Impact of Vaginal Aging questionnaire: a multidimensional measure of the impact of vaginal symptoms on functioning and well-being in postmenopausal women. |date=02.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24983271 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280352 }} * {{medline-title |title=Growth and feed conversion efficiency of Dorper and Rambouillet lambs. |date=10.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23893989 |full-text-url=https://sci-hub.do/10.2527/jas.2012-6226 }} ==PTGS2== * {{medline-title |title=Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31811565 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062590 }} * {{medline-title |title=Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism. |date=21.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31113465 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528237 }} * {{medline-title |title=Analysis of molecular networks and targets mining of Chinese herbal medicines on anti-aging. |date=28.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28031022 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198498 }} * {{medline-title |title=Coordinated gene expression of neuroinflammatory and cell signaling markers in dorsolateral prefrontal cortex during human brain development and aging. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25329999 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203852 }} * {{medline-title |title=Coordination of gene expression of arachidonic and docosahexaenoic acid cascade enzymes during human brain development and aging. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24963629 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070994 }} * {{medline-title |title=Nodes and biological processes identified on the basis of network analysis in the brain of the senescence accelerated mice as an Alzheimer's disease animal model. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24194717 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810591 }} ==PTX3== * {{medline-title |title=Aerobic Training Down-Regulates Pentraxin 3 and Pentraxin 3/Toll-Like Receptor 4 Ratio, Irrespective of Oxidative Stress Response, in Elderly Subjects. |date=27.01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32012711 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070734 }} * {{medline-title |title=Sex Differences in the Association Between Pentraxin 3 and Cognitive Decline: The Cardiovascular Health Study. |date=13.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31808814 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357589 }} * {{medline-title |title=Changes in Proteomic Profiles are Related to Changes in BMI and Fat Distribution During 10 Years of Aging. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31804015 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986305 }} * {{medline-title |title=Inflammatory Long Pentraxin 3 is Associated with Leukocyte Telomere Length in Night-Shift Workers. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28536575 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422482 }} * {{medline-title |title=Age-dependent cellular reactions of the human immune system of humanized NOD scid gamma mice on LPS stimulus. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28162006 |full-text-url=https://sci-hub.do/10.1177/1753425917690814 }} * {{medline-title |title=Elevated pentraxin 3 level at the early stage of exercise training is associated with reduction of arterial stiffness in middle-aged and older adults. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26467819 |full-text-url=https://sci-hub.do/10.1038/jhh.2015.105 }} ==RB1== * {{medline-title |title=Expression of p16 in nodular fasciitis: an implication for self-limited and inflammatory nature of the lesion. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31933915 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945175 }} * {{medline-title |title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. |date=15.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352 }} * {{medline-title |title=Mesenchymal stromal cells having inactivated [[RB1]] survive following low irradiation and accumulate damaged DNA: Hints for side effects following radiotherapy. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27124644 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323029 }} * {{medline-title |title=Suppression of [[RAD21]] Induces Senescence of MDA-[[MB]]-231 Human Breast Cancer Cells Through [[RB1]] Pathway Activation Via c-Myc Downregulation. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26529363 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|title=Age-dependent changes in inflammation and extracellular matrix in bovine oviduct epithelial cells during the post-ovulatory phase. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27580129 |full-text-url=https://sci-hub.do/10.1002/mrd.22693 }} * {{medline-title |title=A transcriptional roadmap to the senescence and differentiation of human oral keratinocytes. |date=01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24398559 |full-text-url=https://sci-hub.do/10.1093/gerona/glt212 }} ==SERPINE1== * {{medline-title |title=Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33041998 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525127 }} * {{medline-title |title=p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to non-nucleoside reverse transcriptase inhibitors. |date=06.2020 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|date=10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26184673 |full-text-url=https://sci-hub.do/10.1002/pros.23045 }} ==ABCG2== * {{medline-title |title=Contribution of senescence in human endometrial stromal cells during proliferative phase to embryo receptivity†. |date=23.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32285109 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313258 }} * {{medline-title |title=[[ABCG2]] rs2231142 variant in hyperuricemia is modified by [[SLC2A9]] and [[SLC22A12]] polymorphisms and cardiovascular risk factors in an elderly community-dwelling population. |date=17.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32183743 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077001 }} * {{medline-title |title=Morphological and immunohistochemical characteristics of the equine corneal epithelium. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30767359 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Preventing Progression of Age-Related Macular Degeneration. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27866147 |full-text-url=https://sci-hub.do/10.1177/1060028016680643 }} * {{medline-title |title=A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging. |date=14.07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27500671 |full-text-url=https://sci-hub.do/10.3791/54136 }} * {{medline-title |title=Mesopic Pelli-Robson contrast sensitivity and MP-1 microperimetry in healthy ageing and age-related macular degeneration. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27225020 |full-text-url=https://sci-hub.do/10.1111/aos.13112 }} * {{medline-title |title=[Age-related Macular Degeneration in the Japanese]. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27164756 }} * {{medline-title |title=Prevalence and Genetic Characteristics of Geographic Atrophy among Elderly Japanese with Age-Related Macular 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markers in the lung of a senescence-accelerated mice model. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26656745 |full-text-url=https://sci-hub.do/10.1016/j.exger.2015.11.021 }} * {{medline-title |title=Melatonin Counteracts at a Transcriptional Level the Inflammatory and Apoptotic Response Secondary to Ischemic Brain Injury Induced by Middle Cerebral Artery Blockade in Aging Rats. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26594596 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642830 }} ==BMPR2== * {{medline-title |title=Human placenta-derived mesenchymal stem cells stimulate ovarian function via miR-145 and bone morphogenetic protein signaling in aged rats. |date=05.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33153492 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643421 }} * {{medline-title |title=Centenarians Overexpress Pluripotency-Related Genes. |date=16.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797 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Differences and similarities to adult disease. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24152725 |full-text-url=https://sci-hub.do/10.1253/circj.cj-13-1180 }} ==BPI== * {{medline-title |title=High TARC plasma levels confer protection to long living individuals by inducing M2 profile. |date=01.2021 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33002742 |full-text-url=https://sci-hub.do/10.1016/j.cyto.2020.155305 }} * {{medline-title |title=Circulating [[BPI]]FB4 Levels Associate With and Influence the Abundance of Reparative Monocytes and Macrophages in Long Living Individuals. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32547549 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272600 }} * {{medline-title |title=The effect of postural deformities on back function and pain in patients with Parkinson's disease. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31177242 |full-text-url=https://sci-hub.do/10.3233/NRE-182637 }} * {{medline-title |title=The expression of the [[BPI]]FB4 and [[CXCR4]] associates with sustained health in long-living individuals from Cilento-Italy. |date=22.01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28121621 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361669 }} * {{medline-title |title=Age-dependent expression of the [[BPI]] gene in Sutai piglets. |date=28.06.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23661399 |full-text-url=https://sci-hub.do/10.4238/2012.April.12.1 }} ==CCL3== * {{medline-title |title=Assessment of neuroinflammation in the aging hippocampus using large-molecule microdialysis: Sex differences and role of purinergic receptors. |date=07.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33166661 |full-text-url=https://sci-hub.do/10.1016/j.bbi.2020.11.013 }} * {{medline-title |title=Microglial translational profiling reveals a convergent [[APOE]] pathway from aging, amyloid, and tau. |date=03.09.2018 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vitro. |date=12.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32777912 |full-text-url=https://sci-hub.do/10.5713/ajas.20.0046 }} * {{medline-title |title=Antioxidant hesperetin improves the quality of porcine oocytes during aging in vitro. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30358012 |full-text-url=https://sci-hub.do/10.1002/mrd.23079 }} * {{medline-title |title=Effect of [[CCNB1]] silencing on cell cycle, senescence, and apoptosis through the p53 signaling pathway in pancreatic cancer. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30069972 |full-text-url=https://sci-hub.do/10.1002/jcp.26816 }} * {{medline-title |title=Hypoxia Upregulates Mitotic Cyclins Which Contribute to the Multipotency of Human Mesenchymal Stem Cells by Expanding Proliferation Lifespan. |date=31.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29463071 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881094 }} * {{medline-title |title=Age-specific gene 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|title=Increased production of functional small extracellular vesicles in senescent endothelial cells. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32101370 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176858 }} * {{medline-title |title=Mitochondrial Signatures in Circulating Extracellular Vesicles of Older Adults with Parkinson's Disease: Results from the EXosomes in PArkiNson's Disease (EXPAND) Study. |date=12.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32059608 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074517 }} * {{medline-title |title=Extracellular Vesicles Derived from Senescent Fibroblasts Attenuate the Dermal Effect on Keratinocyte Differentiation. |date=04.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32033114 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037765 }} ==CES1== * {{medline-title |title=[Comparative Study of Hydrolase Activity in Skin with Liver and Intestine, and Its Aging Relation of Carboxylesterase Expression in Cynomolgus Monkey and Beagle Dog]. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31061351 |full-text-url=https://sci-hub.do/10.1248/yakushi.18-00228 }} * {{medline-title |title=Age-Dependent Absolute Abundance of Hepatic Carboxylesterases ([[CES1]] and [[CES2]]) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27895113 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267516 }} * {{medline-title |title=Identifying clinically relevant sources of variability: The clopidogrel challenge. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27557470 |full-text-url=https://sci-hub.do/10.1002/cpt.459 }} * {{medline-title |title=Age-Dependent Human Hepatic Carboxylesterase 1 ([[CES1]]) and Carboxylesterase 2 ([[CES2]]) Postnatal Ontogeny. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26825642 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potential oncogene in human melanoma. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 }} * {{medline-title |title=Age-dependent alterations in neuronal activity in the hippocampus and visual cortex in a mouse model of Juvenile Neuronal Ceroid Lipofuscinosis ([[CLN3]]). |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28042098 |full-text-url=https://sci-hub.do/10.1016/j.nbd.2016.12.022 }} * {{medline-title |title=Photoreceptor phagosome processing defects and disturbed autophagy in retinal pigment epithelium of Cln3Δex1-6 mice modelling juvenile neuronal ceroid lipofuscinosis (Batten disease). |date=15.12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26450516 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654058 }} * {{medline-title |title=Finding the most appropriate mouse model of juvenile [[CLN3]] (Batten) disease for therapeutic studies: the importance of genetic background and gender. |date=04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26035843 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381334 }} * {{medline-title |title=Xbp1 directs global repression of budding yeast transcription during the transition to quiescence and is important for the longevity and reversibility of the quiescent state. |date=10.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24204289 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814307 }} ==CXCR1== * {{medline-title |title=Harmful neutrophil subsets in patients with ischemic stroke: Association with disease severity. |date=07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31355307 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624098 }} * {{medline-title |title=Knockdown of IL-8 Provoked Premature Senescence of Placenta-Derived Mesenchymal Stem Cells. |date=15.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28418782 |full-text-url=https://sci-hub.do/10.1089/scd.2016.0324 }} * {{medline-title |title=The matrikine N-acetylated proline-glycine-proline induces premature senescence of nucleus pulposus cells via [[CXCR1]]-dependent ROS accumulation and DNA damage and reinforces the destructive effect of these cells on homeostasis of intervertebral discs. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27769935 |full-text-url=https://sci-hub.do/10.1016/j.bbadis.2016.10.011 }} * {{medline-title |title=Habitual physical activity is associated with the maintenance of neutrophil migratory dynamics in healthy older adults. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26928196 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929133 }} * {{medline-title |title=Activation profile of [[CXCL8]]-stimulated neutrophils and aging. |date=03.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23433787 |full-text-url=https://sci-hub.do/10.1016/j.cyto.2013.01.016 }} ==DKC1== * {{medline-title |title=CD8 T-cell senescence and skewed lymphocyte subsets in young Dyskeratosis Congenita patients with [[PARN]] and [[DKC1]] mutations. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32452087 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521304 }} * {{medline-title |title=Successful liver transplantation in short telomere syndromes without bone marrow failure due to [[DKC1]] mutation. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32166868 |full-text-url=https://sci-hub.do/10.1111/petr.13695 }} * {{medline-title |title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655 }} * {{medline-title |title=Cinnamaldehyde and eugenol change the expression folds of [[AKT1]] and [[DKC1]] genes and decrease the telomere length of human adipose-derived stem cells (hASCs): An experimental and in silico study. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28392905 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378970 }} * {{medline-title |title=Molecular adaptation of telomere associated genes in mammals. |date=15.11.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24237966 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833184 }} ==DMP1== * {{medline-title |title=[[GREM1]] inhibits osteogenic differentiation, senescence and BMP transcription of adipose-derived stem cells. |date=09.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32151168 |full-text-url=https://sci-hub.do/10.1080/03008207.2020.1736054 }} * {{medline-title |title=Cx43 overexpression in osteocytes prevents osteocyte apoptosis and preserves cortical bone quality in aging mice. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29978155 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029870 }} * {{medline-title |title=[i]Dmp1[/i] Null Mice Develop a Unique Osteoarthritis-like Phenotype. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27766035 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069442 }} * {{medline-title |title=Decline in calcitonin receptor expression in osteocytes with age. |date=05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24516262 |full-text-url=https://sci-hub.do/10.1530/JOE-13-0524 }} * {{medline-title |title=Novel sandwich ELISAs for rat [[DMP1]]: age-related decrease of circulatory [[DMP1]] levels in male rats. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24076023 |full-text-url=https://sci-hub.do/10.1016/j.bone.2013.09.013 }} ==DRD4== * {{medline-title |title=ADHD risk genes involved in dopamine signaling and metabolism are associated with reduced estimated life expectancy at young adult follow-up in hyperactive and control children. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637915 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|title=Depression-like behavior is dependent on age in male SAMP8 mice. |date=04.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23559311 |full-text-url=https://sci-hub.do/10.1007/s10522-013-9420-0 }} * {{medline-title |title=Swallowing disorders in nursing home residents: how can the problem be explained? |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23449951 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581290 }} ==E2F3== * {{medline-title |title=Time-course transcriptome analysis of medullary thymic epithelial cells in the early phase of thymic involution. |date=07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29730547 |full-text-url=https://sci-hub.do/10.1016/j.molimm.2018.04.010 }} * {{medline-title |title=miR-34a promotes fibrosis in aged lungs by inducing alveolarepithelial dysfunctions. |date=01.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27979858 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374304 }} * {{medline-title |title=Global transcriptional profiling reveals distinct functions of thymic stromal subsets and age-related changes during thymic involution. |date=09.10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25284794 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194175 }} * {{medline-title |title=Tumor-suppressive microRNA-449a induces growth arrest and senescence by targeting [[E2F3]] in human lung cancer cells. |date=28.03.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24211326 |full-text-url=https://sci-hub.do/10.1016/j.canlet.2013.10.031 }} * {{medline-title |title=Elevated miR-34c-5p mediates dermal fibroblast senescence by ultraviolet irradiation. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23983607 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753410 }} ==ERAS== * {{medline-title |title=Enhanced Recovery After Surgery: Are the Principles Applicable to Adult and Geriatric Acute Care and Trauma Surgery? |date=03.2019 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Undergoing Elective Colorectal Laparoscopic Surgery within an [[ERAS]] Protocol. |date=11-12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28044948 |full-text-url=https://sci-hub.do/10.21614/chirurgia.111.6.476 }} ==FBL== * {{medline-title |title=APPLICATION OF A NOVEL QUANTITATIVE TRACTOGRAPHY-BASED ANALYSIS OF DIFFUSION TENSOR IMAGING TO EXAMINE FIBER BUNDLE LENGTH IN HUMAN CEREBRAL WHITE MATTER. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27721932 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055128 }} * {{medline-title |title=Cognitive reserve moderates the relationship between neuropsychological performance and white matter fiber bundle length in healthy older adults. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26961092 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083104 }} * {{medline-title |title=Fiber bundle length and cognition: a length-based tractography MRI study. |date=12.2015 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|date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31547780 |full-text-url=https://sci-hub.do/10.1177/0164027519876125 }} * {{medline-title |title=Association of tenacious goal pursuit and flexible goal adjustment with out-of-home mobility among community-dwelling older people. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30449015 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682663 }} * {{medline-title |title=Assimilative and accommodative coping in older adults with and without sensory impairment: four-year change and prospective relations with affective well-being. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30407084 |full-text-url=https://sci-hub.do/10.1080/13607863.2018.1479833 }} * {{medline-title |title=Age stereotypes, flexible goal adjustment, and well-being among Chinese older adults. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28635315 |full-text-url=https://sci-hub.do/10.1080/13548506.2017.1344253 }} ==FOXA1== * {{medline-title |title=Analyses of an epigenetic switch involved in the activation of pioneer factor [[FOXA1]] leading to the prognostic value of estrogen receptor and [[FOXA1]] co-expression in breast cancer. |date=28.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31562808 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782010 }} * {{medline-title |title=The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese. |date=05.06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883365 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046244 }} * {{medline-title |title=[[FOXA1]] and [[SOX9]] Expression in the Developing Urogenital Sinus of the Tammar Wallaby (Macropus eugenii). |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26406875 |full-text-url=https://sci-hub.do/10.1159/000439499 }} * {{medline-title |title=Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells. |date=03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761685 |full-text-url=https://sci-hub.do/10.1134/S0006297915030062 }} * {{medline-title |title=Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-[[MADD]] locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951664 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066205 }} ==FOXN1== * {{medline-title |title=Thymic rejuvenation via [[FOXN1]]-reprogrammed embryonic fibroblasts (FREFs) to counteract age-related inflammation. |date=17.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32790650 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526556 }} * {{medline-title |title=Role of Bone Marrow Maturity, Insulin-Like Growth Factor 1 Receptor, and Forkhead Box Protein N1 in Thymic Involution and Rejuvenation. |date=10.2016 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adaptogenic effects of herbal extracts on isolated brain cells using systems biology. |date=15.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 |full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 }} * {{medline-title |title=Introduction to FOXO Biology. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30414140 |full-text-url=https://sci-hub.do/10.1007/978-1-4939-8900-3_1 }} * {{medline-title |title=FOXO in Neural Cells and Diseases of the Nervous System. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29433734 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881381 }} * {{medline-title |title=FOXO Transcriptional Factors and Long-Term Living. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28894507 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574317 }} * {{medline-title |title=Long live FOXO: unraveling the role of FOXO proteins in aging and longevity. |date=04.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26643314 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783344 }} ==GDF9== * {{medline-title |title=Prediction of ovarian aging using ovarian expression of [[BMP15]], [[GDF9]], and C-[[KIT]]. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32223330 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221484 }} * {{medline-title |title=Single xenotransplant of rat brown adipose tissue prolonged the ovarian lifespan of aging mice by improving follicle survival. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31389140 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826128 }} * {{medline-title |title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model. |date=18.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463 }} * {{medline-title |title=Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25786490 |full-text-url=https://sci-hub.do/10.1071/RD14472 }} * {{medline-title |title=Identification of a mutation in [[GDF9]] as a novel cause of diminished ovarian reserve in young women. |date=09.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23851219 |full-text-url=https://sci-hub.do/10.1093/humrep/det291 }} ==GGCT== * {{medline-title |title=Blockade of γ-Glutamylcyclotransferase Enhances Docetaxel Growth Inhibition of Prostate Cancer Cells. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31519583 |full-text-url=https://sci-hub.do/10.21873/anticanres.13666 }} * {{medline-title |title=Mechanisms of Tumor Growth Inhibition by Depletion of γ-Glutamylcyclotransferase ([[GGCT]]): A Novel Molecular Target for Anticancer Therapy. |date=14.07.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30011933 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073726 }} * {{medline-title |title=Depletion of gamma-glutamylcyclotransferase in cancer cells induces autophagy followed by cellular senescence. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29736310 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934555 }} * {{medline-title |title=Prohibitin-2 is a novel regulator of p21 induced by depletion of γ-glutamylcyclotransferase. |date=29.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29307834 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.01.029 }} * {{medline-title |title=Depletion of γ-glutamylcyclotransferase inhibits breast cancer cell growth via cellular senescence induction mediated by CDK inhibitor upregulation. |date=22.09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27658708 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034417 }} ==GIT2== * {{medline-title |title=The [[RXFP3]] receptor is functionally associated with cellular responses to oxidative stress and DNA damage. |date=03.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31794429 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932917 }} * {{medline-title |title=Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic [[GIT2]] in aging trajectories. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31574270 |full-text-url=https://sci-hub.do/10.1016/j.mad.2019.111150 }} * {{medline-title |title=[[GIT2]]-A keystone in ageing and age-related disease. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452267 |full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.002 }} * {{medline-title |title=Genomic deletion of [[GIT2]] induces a premature age-related thymic dysfunction and systemic immune system disruption. |date=04.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28260693 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391227 }} * {{medline-title |title=[[GIT2]] Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26834700 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716144 }} ==GPX4== * {{medline-title |title=l-carnitine supplementation during in vitro culture regulates oxidative stress in embryos from bovine aged oocytes. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31837632 |full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2019.11.036 }} * {{medline-title |title=Dietary Selenium Supplementation Ameliorates Female Reproductive Efficiency in Aging Mice. |date=11.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31835711 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969897 }} * {{medline-title |title=Resveratrol improves in vitro maturation of oocytes in aged mice and humans. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29778389 |full-text-url=https://sci-hub.do/10.1016/j.fertnstert.2018.01.020 }} * {{medline-title |title=Differential menopause- versus aging-induced changes in oxidative stress and circadian rhythm gene markers. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28408140 |full-text-url=https://sci-hub.do/10.1016/j.mad.2017.04.002 }} * {{medline-title |title=Maternal obesity in the rat impairs male offspring aging of the testicular antioxidant defence system. |date=09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28063465 |full-text-url=https://sci-hub.do/10.1071/RD16277 }} ==GRK2== * {{medline-title |title=G protein-coupled receptor kinase 2 modifies the ability of Caenorhabditis elegans to survive oxidative stress. |date=16.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33064264 |full-text-url=https://sci-hub.do/10.1007/s12192-020-01168-z }} * {{medline-title |title=G protein coupled receptor kinases modulate Caenorhabditis elegans reactions to heat stresses. |date=01.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32768194 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.07.121 }} * {{medline-title |title=Loss of dynamic regulation of G protein-coupled receptor kinase 2 by nitric oxide leads to cardiovascular dysfunction with aging. |date=01.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32216616 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346533 }} * {{medline-title |title=Senescent Cells Differentially Translate Senescence-Related mRNAs Via Ribosome Heterogeneity. |date=18.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30285098 |full-text-url=https://sci-hub.do/10.1093/gerona/gly228 }} * {{medline-title |title=Effects of exercise training on cardiovascular adrenergic system. |date=28.11.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24348425 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842896 }} ==HAS2== * {{medline-title |title=Sodium tanshinone IIA sulfonate restrains fibrogenesis through induction of senescence in mice with induced deep endometriosis. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32651107 |full-text-url=https://sci-hub.do/10.1016/j.rbmo.2020.04.006 }} * {{medline-title |title=Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063508 |full-text-url=https://sci-hub.do/10.1007/s13577-017-0185-7 }} * {{medline-title |title=Microvasculature of the Mouse Cerebral Cortex Exhibits Increased Accumulation and Synthesis of Hyaluronan With Aging. |date=01.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28482035 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075594 }} * {{medline-title |title=Hyaluronan synthase 2 regulates fibroblast senescence in pulmonary fibrosis. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26987798 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383204 }} * {{medline-title |title=Age-associated changes in gene expression of goat oocytes. |date=01.09.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23746875 |full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2013.04.019 }} ==HCN2== * {{medline-title |title=Protein expression changes of [[HCN1]] and [[HCN2]] in hippocampal subregions of gerbils during the normal aging process. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32128096 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038419 }} * {{medline-title |title=Characteristics of hyperpolarization-activated cyclic nucleotide-gated channels in dorsal root ganglion neurons at different ages and sizes. |date=11.11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26379059 |full-text-url=https://sci-hub.do/10.1097/WNR.0000000000000455 }} * {{medline-title |title=Age-associated expression of HCN channel isoforms in rat sinoatrial node. |date=02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26341471 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935443 }} * {{medline-title |title=Altered expression of hyperpolarization-activated cyclic nucleotide-gated channels and microRNA-1 and -133 in patients with age-associated atrial fibrillation. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26005035 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526032 }} * {{medline-title |title=Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse. |date=27.02.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761792 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352274 }} ==HSPA8== * {{medline-title |title=Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31733664 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939615 }} * {{medline-title |title=Influence of Normal Aging on Brain Autophagy: A Complex Scenario. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30914945 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421305 }} * {{medline-title |title=Nitric oxide contributes to protein homeostasis by S-nitrosylations of the chaperone [[HSPA8]] and the ubiquitin ligase UBE2D. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30368041 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202877 }} * {{medline-title |title=Cerebrospinal Fluid Concentration of Key Autophagy Protein Lamp2 Changes Little During Normal Aging. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29867441 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952035 }} * {{medline-title |title=Age-Related Decrease in Heat Shock 70-kDa Protein 8 in Cerebrospinal Fluid Is Associated with Increased Oxidative Stress. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27507943 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in Adult Rats Brain Following Intracerebral Hemorrhage. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27568302 |full-text-url=https://sci-hub.do/10.1007/s10571-016-0421-9 }} * {{medline-title |title=2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling. |date=01.09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26190651 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663076 }} ==IRS2== * {{medline-title |title=Effects of Heshouwuyin on gene expression of the insulin/IGF signalling pathway in rat testis and spermatogenic cells. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33264567 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717869 }} * {{medline-title |title=Involvement of insulin receptor substrates in cognitive impairment and Alzheimer's disease. |date=08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30964050 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524492 }} * {{medline-title |title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014 }} * {{medline-title |title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688 |full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003 }} * {{medline-title |title=Analysis of [[MTNR1B]] gene polymorphisms in relationship with [[IRS2]] gene variants, epicardial fat thickness, glucose homeostasis and cognitive performance in the elderly. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28708046 |full-text-url=https://sci-hub.do/10.1080/07420528.2017.1340894 }} ==KCNB1== * {{medline-title |title=Oxidation of [[KCNB1]] potassium channels in the murine brain during aging is associated with cognitive impairment. |date=14.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30922570 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471606 }} * {{medline-title |title=Oxidation of [[KCNB1]] Potassium Channels Causes Neurotoxicity and Cognitive Impairment in a Mouse Model of Traumatic Brain Injury. |date=26.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27798188 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098843 }} * {{medline-title |title=Oxidation of K( ) Channels in Aging and Neurodegeneration. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27114846 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809605 }} * {{medline-title |title=Oxidation of [[KCNB1]] K( ) channels in central nervous system and beyond. |date=26.05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24921000 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050120 }} * {{medline-title |title=Molecular mechanisms underlying the apoptotic effect of [[KCNB1]] K channel oxidation. |date=08.02.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23275378 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567663 }} ==KISS1== * {{medline-title |title=In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31520345 |full-text-url=https://sci-hub.do/10.1007/s10522-019-09834-1 }} * {{medline-title |title=Kisspeptin level in the aging ovary is regulated by the sympathetic nervous system. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27856623 |full-text-url=https://sci-hub.do/10.1530/JOE-16-0181 }} * {{medline-title |title=Kisspeptin across the human lifespan:evidence from animal studies and beyond. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27340201 |full-text-url=https://sci-hub.do/10.1530/JOE-15-0538 }} * {{medline-title |title=Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25765287 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475460 }} * {{medline-title |title=[Profiles of reproduction-related mRNA expressions in hypothalamus of female mice with advancing age]. |date=17.12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24548401 }} ==LIF== * {{medline-title |title=Use of the Reversible Myogenic to Lipogenic Transdifferentiation Switch for the Design of Pre-clinical Drug Screening in Idiopathic Pulmonary Fibrosis. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33042971 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523217 }} * {{medline-title |title=Aminopeptidase N expression in the endometrium could affect endometrial receptivity. |date=25.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31056265 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.04.174 }} * {{medline-title |title=Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats. |date=15.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30445025 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814304 }} * {{medline-title |title=Assaying human neutrophil elastase activity by capillary zone electrophoresis combined with laser-induced fluorescence. |date=06.11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26454788 |full-text-url=https://sci-hub.do/10.1016/j.chroma.2015.09.084 }} * {{medline-title |title=iPSCs, aging and age-related diseases. |date=25.09.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24784583 |full-text-url=https://sci-hub.do/10.1016/j.nbt.2014.04.004 }} ==LONP1== * {{medline-title |title=Improved mitochondrial stress response in long-lived Snell dwarf mice. |date=12.2019 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key enzyme controlling mitochondrial bioenergetics in cancer. |date=10-12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27308364 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905204 }} ==MAPK14== * {{medline-title |title=Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31811565 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062590 }} * {{medline-title |title=Chlorella vulgaris modulates the expression of senescence-associated genes in replicative senescence of human diploid fibroblasts. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31642042 |full-text-url=https://sci-hub.do/10.1007/s11033-019-05140-8 }} * {{medline-title |title=Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway. |date=10.2018 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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225354 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140116 }} * {{medline-title |title=[[MARCKS]] contributes to stromal cancer-associated fibroblast activation and facilitates ovarian cancer metastasis. |date=21.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27081703 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122339 }} * {{medline-title |title=[[MARCKS]]-dependent mucin clearance and lipid metabolism in ependymal cells are required for maintenance of forebrain homeostasis during aging. |date=10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26010231 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568964 }} * {{medline-title |title=The novel protein kinase C epsilon isoform at the adult neuromuscular synapse: location, regulation by synaptic activity-dependent muscle contraction through TrkB signaling and coupling to ACh release. |date=10.02.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761522 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348107 }} * {{medline-title |title=Low hippocampal PI(4,5)P₂ contributes to reduced cognition in old mice as a result of loss of [[MARCKS]]. |date=04.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23434911 |full-text-url=https://sci-hub.do/10.1038/nn.3342 }} ==MGP== * {{medline-title |title=Circulating Vitamin K Is Inversely Associated with Incident Cardiovascular Disease Risk among Those Treated for Hypertension in the Health, Aging, and Body Composition Study (Health ABC). |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28356433 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404216 }} * {{medline-title |title=Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma. |date=21.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28058013 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|title=Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31476350 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059097 }} * {{medline-title |title=The underlying mechanism of proinflammatory NF-κB activation by the mTORC2/Akt/IKKα pathway during skin aging. |date=16.08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27486771 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288141 }} * {{medline-title |title=Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan. |date=10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25059582 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172536 }} * {{medline-title |title=Genetic analysis of TOR complex gene variation with human longevity: a nested case-control study of American men of Japanese ancestry. |date=02.2015 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|title=[Role and alterations of DNA methylation during the aging and cancer]. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647 |full-text-url=https://sci-hub.do/10.1556/650.2018.30927 }} * {{medline-title |title=Age-related increase in Wnt inhibitor causes a senescence-like phenotype in human cardiac stem cells. |date=03.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28435069 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.04.110 }} * {{medline-title |title=Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma. |date=21.12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28058013 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175245 }} * {{medline-title |title=The intrinsic stiffness of human trabecular meshwork cells increases with senescence. |date=20.06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25915531 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558157 }} * {{medline-title |title=Effects of age on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in humans. |date=02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24184314 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877168 }} ==SMAD4== * {{medline-title |title=A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30843125 |full-text-url=https://sci-hub.do/10.1007/s00595-019-01789-7 }} * {{medline-title |title=E47 Governs the [[MYC]]-CDKN1B/p27 -RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16 and Wild-Type p53. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003124 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039985 }} * {{medline-title |title=iTRAQ-based proteomic profiling of granulosa cells from lamb and ewe after superstimulation. |date=01.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28708522 |full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2017.06.014 }} * {{medline-title |title=miR-431 promotes differentiation and regeneration of old skeletal muscle by targeting Smad4. |date=01.08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26215566 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536309 }} * {{medline-title |title=Loss of smad4 in Sertoli and Leydig cells leads to testicular dysgenesis and hemorrhagic tumor formation in mice. |date=03.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24501173 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076392 }} ==SMN2== * {{medline-title |title=Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment. |date=01.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31589162 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819103 }} * {{medline-title |title=Type 0 Spinal Muscular Atrophy: Further Delineation of Prenatal and Postnatal Features in 16 Patients. |date=29.11.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27911332 |full-text-url=https://sci-hub.do/10.3233/JND-160177 }} * {{medline-title |title=Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy. |date=27.09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27621445 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047168 }} * {{medline-title |title=Motor neuron disease. [[SMN2]] splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy. |date=08.08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25104390 |full-text-url=https://sci-hub.do/10.1126/science.1250127 }} * {{medline-title |title=Development and characterization of an [[SMN2]]-based intermediate mouse model of Spinal Muscular Atrophy. |date=01.05.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23390132 |full-text-url=https://sci-hub.do/10.1093/hmg/ddt037 }} ==SMS== * {{medline-title |title=Does a Live Performance Impact Synchronization to Musical Rhythm in Cognitively Impaired Elderly? |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33104027 |full-text-url=https://sci-hub.do/10.3233/JAD-200521 }} * {{medline-title |title=Testing the effectiveness of physical activity advice delivered via text messaging vs. human phone advisors in a Latino population: The On The Move randomized controlled trial design and methods. |date=08.2020 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combined effects of salinity and lipopolysaccharides on the immune response of juvenile Takifugu fasciatus. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30656452 |full-text-url=https://sci-hub.do/10.1007/s10695-018-0607-9 }} * {{medline-title |title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes. |date=28.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680560 }} * {{medline-title |title=Daily Socs1 rhythms alter with aging differentially in peripheral clocks in male Wistar rats: therapeutic effects of melatonin. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28331994 |full-text-url=https://sci-hub.do/10.1007/s10522-017-9687-7 }} * {{medline-title |title=Differential response to intrahippocampal interleukin-4/interleukin-13 in aged and exercise mice. |date=20.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27916728 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800496 }} * {{medline-title |title=Aging diminishes the resistance of AO rats to EAE: putative role of enhanced generation of GM-CSF Expressing CD4 T cells in aged rats. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448779 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596406 }} ==SP1== * {{medline-title |title=The effects and mechanism of collagen peptide and elastin peptide on skin aging induced by D-galactose combined with ultraviolet radiation. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32717457 |full-text-url=https://sci-hub.do/10.1016/j.jphotobiol.2020.111964 }} * {{medline-title |title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. |date=15.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220 |full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063 }} * {{medline-title |title=Downregulation of [[CITED2]] contributes to TGFβ-mediated senescence of tendon-derived stem cells. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28084522 |full-text-url=https://sci-hub.do/10.1007/s00441-016-2552-1 }} * {{medline-title |title=Homocysteine accelerates senescence of endothelial cells via DNA hypomethylation of human telomerase reverse transcriptase. |date=01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25359865 |full-text-url=https://sci-hub.do/10.1161/ATVBAHA.114.303899 }} * {{medline-title |title=A functional and genetic analysis of [[SOD2]] promoter variants and their contribution to age-related hearing loss. |date=07-08.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23500038 |full-text-url=https://sci-hub.do/10.1016/j.mad.2013.02.009 }} ==SSB== * {{medline-title |title=Modelling the Effects of Beverage Substitution during Adolescence on Later Obesity Outcomes in Early Adulthood: Results from the Raine Study. |date=03.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31816850 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950484 }} * {{medline-title |title=WHIRLY1 Occupancy Affects Histone Lysine Modification and [i]WRKY53[/i] Transcription in [i]Arabidopsis[/i] Developmental Manner. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30405658 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202938 }} * {{medline-title |title=Modelled health benefits of a sugar-sweetened beverage tax across different socioeconomic groups in Australia: A cost-effectiveness and equity analysis. |date=06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28654688 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486958 }} * {{medline-title |title=Reduction of Sugar-Sweetened Beverage Consumption in Elementary School Students Using an Educational Curriculum of Beverage Sugar Content. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28620628 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464517 }} * {{medline-title |title=Interannual and Spatial Variability in Maturity of Walleye Pollock Gadus chalcogrammus and Implications for Spawning Stock Biomass Estimates in the Gulf of Alaska. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27736982 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063383 }} ==TBC1D1== * {{medline-title |title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. |date=02.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688 |full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003 }} * {{medline-title |title=Calorie restriction leads to greater Akt2 activity and glucose uptake by insulin-stimulated skeletal muscle from old rats. |date=01.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26739650 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796740 }} * {{medline-title |title=Insulin Signaling and Glucose Uptake in the Soleus Muscle of 30-Month-Old Rats After Calorie Restriction With or Without Acute Exercise. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26341783 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864161 }} * {{medline-title |title=Effects of sex and age on chicken [[TBC1D1]] gene mRNA expression. |date=13.07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26214451 |full-text-url=https://sci-hub.do/10.4238/2015.July.13.16 }} * {{medline-title |title=AMPK and insulin action--responses to ageing and high fat diet. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23671593 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645997 }} ==TGFB1== * {{medline-title |title=Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season. |date=21.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31864349 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925900 }} * {{medline-title |title=[[TGFB1]]-Mediated Gliosis in Multiple Sclerosis Spinal Cords Is Favored by the Regionalized Expression of [[HOXA5]] and the Age-Dependent Decline in Androgen Receptor Ligands. |date=26.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31779094 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928867 }} * {{medline-title |title=Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease. |date=11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28812215 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665708 }} * {{medline-title |title=Seminal plasma transforming growth factor-β, activin A and follistatin fluctuate within men over time. |date=10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27609985 |full-text-url=https://sci-hub.do/10.1093/humrep/dew185 }} * {{medline-title |title=No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes. |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26946122 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841709 }} ==TLR1== * {{medline-title |title=Effects of aging and lifelong aerobic exercise on expression of innate immune components in human skeletal muscle. |date=01.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32969782 |full-text-url=https://sci-hub.do/10.1152/japplphysiol.00615.2020 }} * {{medline-title |title=Association of TLR gene variants in a Czech Red Pied cattle population with reproductive traits. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31901560 |full-text-url=https://sci-hub.do/10.1016/j.vetimm.2019.109997 }} * {{medline-title |title=Decreased [[NLRP3]] inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203400 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869149 }} * {{medline-title |title=Changes in the expression of the Toll-like receptor system in the aging rat kidneys. |date=2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24810370 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014502 }} * {{medline-title |title=Reduced bioenergetics and toll-like receptor 1 function in human polymorphonuclear leukocytes in aging. |date=02.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24595889 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969281 }} ==TLR8== * {{medline-title |title=Effects of aging and lifelong aerobic exercise on expression of innate immune components in human skeletal muscle. |date=01.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32969782 |full-text-url=https://sci-hub.do/10.1152/japplphysiol.00615.2020 }} * {{medline-title |title=[[TLR8]]-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy. |date=08.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30344014 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050437 }} * {{medline-title |title=Controlling T cell senescence in the tumor microenvironment for tumor immunotherapy. |date=03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25949919 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404789 }} * {{medline-title |title=Cathelicidin related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25834936 |full-text-url=https://sci-hub.do/10.1016/j.patbio.2015.03.002 }} * {{medline-title |title=[[TLR8]] signaling enhances tumor immunity by preventing tumor-induced T-cell senescence. |date=10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25231413 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287933 }} ==TMPRSS2== * {{medline-title |title=[[ACE2]]/[[ADAM17]]/[[TMPRSS2]] Interplay May Be the Main Risk Factor for COVID-19. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33117379 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575774 }} * {{medline-title |title=Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 [[ACE2]]-[[TMPRSS2]]-Furin-[[DPP4]] Axis. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013423 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510459 }} * {{medline-title |title=Susceptibility to COVID-19 in populations with health disparities: Posited involvement of mitochondrial disorder, socioeconomic stress, and pollutants. |date=09.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32905655 |full-text-url=https://sci-hub.do/10.1002/jbt.22626 }} * {{medline-title |title=Expression of the SARS-CoV-2 Entry Proteins, [[ACE2]] and [[TMPRSS2]], in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age. |date=03.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32379417 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241737 }} * {{medline-title |title=SARS-CoV-2 receptor [[ACE2]] and [[TMPRSS2]] are primarily expressed in bronchial transient secretory cells. |date=18.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32246845 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232010 }} ==TRH== * {{medline-title |title=Neonatal exposure to bisphenol A alters the hypothalamic-pituitary-thyroid axis in female rats. |date=15.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29305326 |full-text-url=https://sci-hub.do/10.1016/j.toxlet.2017.12.029 }} * {{medline-title |title=Effect of dietary carbohydrates and time of year on ACTH and cortisol concentrations in adult and aged horses. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29195115 |full-text-url=https://sci-hub.do/10.1016/j.domaniend.2017.10.005 }} * {{medline-title |title=The role of Thyrotropin Releasing Hormone in aging and neurodegenerative diseases. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24199031 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817016 }} * {{medline-title |title=Aging-reversing properties of thyrotropin-releasing hormone. |date=02.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23895526 |full-text-url=https://sci-hub.do/10.2174/1874609811306010012 }} * {{medline-title |title=Cancer-related fatigue, inflammation and thyrotropin-releasing hormone. |date=12.2012 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23387883 |full-text-url=https://sci-hub.do/10.2174/1874609811205030005 }} ==TRPM8== * {{medline-title |title=Morphological and functional changes in [[TRPM8]]-expressing corneal cold thermoreceptor neurons during aging and their impact on tearing in mice. |date=01.08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29664111 |full-text-url=https://sci-hub.do/10.1002/cne.24454 }} * {{medline-title |title=A comparative study on the therapeutic effect of [[TRPV1]], [[TRPA1]], and [[TRPM8]] agonists on swallowing dysfunction associated with aging and neurological diseases. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28799699 |full-text-url=https://sci-hub.do/10.1111/nmo.13185 }} * {{medline-title |title=Roles of [[TRPM8]] Ion Channels in Cancer: Proliferation, Survival, and Invasion. |date=23.10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26512697 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695882 }} * {{medline-title |title=Function and postnatal changes of dural afferent fibers expressing [[TRPM8]] channels. |date=26.06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26111800 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480580 }} * {{medline-title |title=Induction of oxidative stress causes functional alterations in mouse urothelium via a [[TRPM8]]-mediated mechanism: implications for aging. |date=06.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24593692 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326884 }} ==VCP== * {{medline-title |title=The role of air pollution and lung function in cognitive impairment. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29467204 |full-text-url=https://sci-hub.do/10.1183/13993003.01963-2017 }} * {{medline-title |title=Better parameters of ventilation-CO₂output relationship predict death in CHF patients. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27215018 }} * {{medline-title |title=Valosin-containing protein is a key mediator between autophagic cell death and apoptosis in adult hippocampal neural stem cells following insulin withdrawal. |date=22.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27000202 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802725 }} * {{medline-title |title=Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis. |date=24.02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912063 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765225 }} * {{medline-title |title=Characterization of C-terminal adaptors, UFD-2 and UFD-3, of CDC-48 on the polyglutamine aggregation in C. elegans. |date=27.03.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25721663 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.02.088 }} ==WAS== * {{medline-title |title=Psychological stress exposure to aged mice causes abnormal feeding patterns with changes in the bout number. |date=09.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129830 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723686 }} * {{medline-title |title=Measuring Work Ability with Its Antecedents: Evaluation of the Work Ability Survey. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28741256 |full-text-url=https://sci-hub.do/10.1007/s10926-017-9720-3 }} * {{medline-title |title=CONSTANCES: a general prospective population-based cohort for occupational and environmental epidemiology: cohort profile. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27884936 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241503 }} * {{medline-title |title=Age-Dependent Defects of Regulatory B Cells in Wiskott-Aldrich Syndrome Gene Knockout Mice. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448644 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598155 }} * {{medline-title |title=Long-term anticoagulation in the extreme elderly with the newer antithrombotics: safe or sorry? |date=05.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23755073 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675301 }}
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