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...esult (MAD 3.16 years, RMSE 3.93 years). A reduced model based on only the top 4 markers ([[ELOVL2]], [[F5]], [[KLF14]], and [[TRIM59]]) resulted in a RMS ...nal genome-wide significant associations were observed on 4q35 at [[F11]] (top SNP rs4253399, intronic to [[F11]]) and on 4q28 at [[FGG]] (rs6536024, 9.7 ...

...esult (MAD 3.16 years, RMSE 3.93 years). A reduced model based on only the top 4 markers ([[ELOVL2]], [[F5]], [[KLF14]], and [[TRIM59]]) resulted in a RMS ...model was deterministic for individuals belonging to these two extreme age categories. The developed method was implemented in a freely available online age pred ...

The cover of RAFT 2035 depicts a raft sitting on top of waves of turbulence. * 5. World-class life-preparation education to postgraduate level will be freely available to everyone. ...

...um creatinine level was used as the assessment criterion (serum creatinine level lower than 115 mmol/L is normal). Factors related to graft function such as ...nal genome-wide significant associations were observed on 4q35 at [[F11]] (top SNP rs4253399, intronic to [[F11]]) and on 4q28 at [[FGG]] (rs6536024, 9.7 ...

...CKD. Hospitalization rates per 1,000 person-years according to KDIGO risk categories were 208-223 ("low risk"), 288-376 ("moderately increased risk"), 363-548 ( ...as attenuated by adjustment for [[ACR]] (HR, 1.15; 95% CI, 0.89-1.48). The top quartile of [[ACR]] had a stronger adjusted association with heart failure ...

...e conditions combined with self-reported overall health, and (c) 2 or more top-10 most common comorbidities. Leisure-time PA (LTPA) and total PA (TPA) wer ...RT1]], p-rpS6 and Bcl2 were examined. The [[MET]] mice exhibited increased level of serum E2 hormone and higher percentage of regular estrous cycles after 6 ...

...formin and sodium-glucose cotransporter-2 inhibitors), [[CAD]], and VHD on top of measures that retard cardiovascular aging are the steadfast underpinning ...earson correlation and logistic regression analysis showed that the plasma level of [[MEF2A]] was negatively correlated with [[CAD]], and with age in the co ...

...focal microscopy. We found that hPMSC treatment markedly decreased the ROS level, SA-β-gal-positive cells number, senescence-associated secretory phenotype ...ith level of proteinuria level or glucose control. In age, sex and glucose level-adjusted regression models, stage 3 CKD patients exhibited significantly el ...

...ith level of proteinuria level or glucose control. In age, sex and glucose level-adjusted regression models, stage 3 CKD patients exhibited significantly el ..., LW increased TSH levels in the pituitary, and melatonin increased the GH level in blood. Our findings indicated that LW improved the cognitive decline in ...

...focal microscopy. We found that hPMSC treatment markedly decreased the ROS level, SA-β-gal-positive cells number, senescence-associated secretory phenotype ...ring ageing. It is as if the immune system was more efficient at the basal level, but less efficient after a stimulation in the old compared to young people ...